Targeting mTOR for the treatment of B cell malignancies

British Journal of Clinical Pharmacology

Volumn , Issue , 2016, Pages 1213-1228

  Lee, Jong Hoon Scott ^a   Vo, Thanh Trang ^a   Fruman, David A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

leukemia; lymphoma; mTOR; rapalogs; rapamycin; TOR KIs

Indexed keywords

2 (4 AMINO 1 ISOPROPYL 1H PYRAZOLO[3,4 D]PYRIMIDIN 3 YL) 1H INDOL 5 OL; 5 [2 (2,6 DIMETHYLMORPHOLINO) 4 MORPHOLINOPYRIDO[2,3 D]PYRIMIDIN 7 YL] 2 METHOXYBENZENEMETHANOL; ASPARAGINASE MACROGOL; AZD 8055; BENDAMUSTINE; BORTEZOMIB; CC 115; CC 223; CLADRIBINE; CYCLOPHOSPHAMIDE; DOXORUBICIN; ETOPOSIDE; EVEROLIMUS; INOTUZUMAB OZOGAMICIN; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MITOXANTRONE; PANOBINOSTAT; PQR 309; PREDNISONE; RAPAMYCIN; RAPAMYCIN DERIVATIVE; RIDAFOROLIMUS; RITUXIMAB; SAPANISERTIB; TEMSIROLIMUS; TORIN 1; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE; VISTUSERTIB;

ACUTE LYMPHOBLASTIC LEUKEMIA; APOPTOSIS; B CELL ACUTE LYMPHOBLASTIC LEUKEMIA; B CELL LEUKEMIA; DRUG MECHANISM; DRUG POTENTIATION; DRUG TARGETING; FOLLICULAR LYMPHOMA; HEMATOLOGIC MALIGNANCY; HUMAN; LARGE CELL LYMPHOMA; MANTLE CELL LYMPHOMA; NONHODGKIN LYMPHOMA; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION;

EID: 84991220105     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/bcp.12888     Document Type: Review

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