메뉴 건너뛰기




Volumn 5, Issue 6, 2008, Pages 357-361

Rapamycin treatment for a child with germline PTEN mutation

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; GROWTH HORMONE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAPAMYCIN; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN C;

EID: 44649203072     PISSN: 17434254     EISSN: 17434262     Source Type: Journal    
DOI: 10.1038/ncponc1112     Document Type: Article
Times cited : (116)

References (22)
  • 1
    • 0032913743 scopus 로고    scopus 로고
    • Proteus syndrome: Diagnostic criteria, differential diagnosis, and patient evaluation
    • Biesecker LG et al. (1999) Proteus syndrome: Diagnostic criteria, differential diagnosis, and patient evaluation. Am J Med Genet 84: 389-395
    • (1999) Am J Med Genet , vol.84 , pp. 389-395
    • Biesecker, L.G.1
  • 2
    • 0035928416 scopus 로고    scopus 로고
    • Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes
    • Zhou X et al. (2001) Association of germline mutation in the PTEN tumour suppressor gene and Proteus and Proteus-like syndromes. Lancet 358: 210-211
    • (2001) Lancet , vol.358 , pp. 210-211
    • Zhou, X.1
  • 3
    • 0036918288 scopus 로고    scopus 로고
    • Germline mutation of the tumour suppressor PTEN in Proteus Syndrome
    • Smith JM et al. (2002) Germline mutation of the tumour suppressor PTEN in Proteus Syndrome. J Med Genet 39: 937-940
    • (2002) J Med Genet , vol.39 , pp. 937-940
    • Smith, J.M.1
  • 4
    • 12344262762 scopus 로고    scopus 로고
    • mTOR, translational control and human disease
    • Tee AR and Blenis J (2005) mTOR, translational control and human disease. Semin Cell Dev Biol 16: 29-37
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 29-37
    • Tee, A.R.1    Blenis, J.2
  • 5
    • 0037182139 scopus 로고    scopus 로고
    • Rapamycin blocks tumor progression: Unlinking immunosuppression from antitumor efficacy
    • Luan FL et al. (2002) Rapamycin blocks tumor progression: unlinking immunosuppression from antitumor efficacy. Transplantation 73: 1565-1572
    • (2002) Transplantation , vol.73 , pp. 1565-1572
    • Luan, F.L.1
  • 6
    • 33845875992 scopus 로고    scopus 로고
    • Cancer phenomics: RET and PTEN as illustrative models
    • Zbuk KM and Eng C (2007) Cancer phenomics: RET and PTEN as illustrative models. Nat Rev Cancer 7: 35-45
    • (2007) Nat Rev Cancer , vol.7 , pp. 35-45
    • Zbuk, K.M.1    Eng, C.2
  • 7
    • 6844252284 scopus 로고    scopus 로고
    • Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation
    • Marsh DJ et al. (1998) Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Hum Mol Genet 7 507-515
    • (1998) Hum Mol Genet , vol.7 , pp. 507-515
    • Marsh, D.J.1
  • 8
    • 33746353046 scopus 로고    scopus 로고
    • LKB1-dependent signaling pathways
    • Alessi DR et al. (2006) LKB1-dependent signaling pathways. Annu Rev Biochem 75: 137-163
    • (2006) Annu Rev Biochem , vol.75 , pp. 137-163
    • Alessi, D.R.1
  • 9
    • 33644827461 scopus 로고    scopus 로고
    • Rapamycin causes regression of astrocytomas in tuberous sclerosis complex
    • Franz DN et al. (2006) Rapamycin causes regression of astrocytomas in tuberous sclerosis complex. Ann Neurol 59: 490-498
    • (2006) Ann Neurol , vol.59 , pp. 490-498
    • Franz, D.N.1
  • 10
    • 33746637660 scopus 로고    scopus 로고
    • Current development of mTOR inhibitors as anticancer agents
    • Faivre S et al. (2006) Current development of mTOR inhibitors as anticancer agents. Nat Rev Drug Discov 5: 671-688
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 671-688
    • Faivre, S.1
  • 11
    • 33947266995 scopus 로고    scopus 로고
    • Upstream signaling inhibition enhances rapamycin effect on growth of kidney cancer cells
    • Costa LJ et al. (2007) Upstream signaling inhibition enhances rapamycin effect on growth of kidney cancer cells. Urology 69 596-602
    • (2007) Urology , vol.69 , pp. 596-602
    • Costa, L.J.1
  • 12
    • 34247370642 scopus 로고    scopus 로고
    • Combining an mTOR antagonist and receptor tyrosine kinase inhibitors for the treatment of prostate cancer
    • Masiello D et al. (2007) Combining an mTOR antagonist and receptor tyrosine kinase inhibitors for the treatment of prostate cancer. Cancer Biol Ther 6: 195-201
    • (2007) Cancer Biol Ther , vol.6 , pp. 195-201
    • Masiello, D.1
  • 13
    • 33746807790 scopus 로고    scopus 로고
    • Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas
    • Doherty L et al. (2006) Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas. Neurology 67 156-158
    • (2006) Neurology , vol.67 , pp. 156-158
    • Doherty, L.1
  • 14
    • 34548332487 scopus 로고    scopus 로고
    • Cancer drugs to treat birth defects
    • Wilkie AO (2007) Cancer drugs to treat birth defects. Nat Genet 39: 1057-1059
    • (2007) Nat Genet , vol.39 , pp. 1057-1059
    • Wilkie, A.O.1
  • 15
    • 0033565956 scopus 로고    scopus 로고
    • Hemangiomas in children
    • Drolet BA et al. (1999) Hemangiomas in children. N Engl J Med 341: 173-181
    • (1999) N Engl J Med , vol.341 , pp. 173-181
    • Drolet, B.A.1
  • 16
    • 0036905115 scopus 로고    scopus 로고
    • Cellular actions of the insulin-like growth factor binding proteins
    • Firth SM and Baxter RC (2002) Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev 23: 824-854
    • (2002) Endocr Rev , vol.23 , pp. 824-854
    • Firth, S.M.1    Baxter, R.C.2
  • 17
    • 1842533011 scopus 로고    scopus 로고
    • Elevated serum insulin-like growth factor binding protein-2 as a prognostic marker in patients with ovarian cancer
    • Baron-Hay S et al. (2004) Elevated serum insulin-like growth factor binding protein-2 as a prognostic marker in patients with ovarian cancer. Clin Cancer Res 10: 1796-1806
    • (2004) Clin Cancer Res , vol.10 , pp. 1796-1806
    • Baron-Hay, S.1
  • 18
    • 0030982864 scopus 로고    scopus 로고
    • Insulin-like growth factor-binding protein-2 in patients with prostate carcinoma and benign prostatic hyperpasia
    • Ho PJ and Baxter RC (1997) Insulin-like growth factor-binding protein-2 in patients with prostate carcinoma and benign prostatic hyperpasia. Clin Endocrinol (Oxf) 46: 145-154
    • (1997) Clin Endocrinol (Oxf) , vol.46 , pp. 145-154
    • Ho, P.J.1    Baxter, R.C.2
  • 19
    • 25644446718 scopus 로고    scopus 로고
    • PTEN-induction in U251 glioma cells decreases the expression of insulin-like growth factor binding protein-2
    • Levitt RJ et al. (2005) PTEN-induction in U251 glioma cells decreases the expression of insulin-like growth factor binding protein-2. Biochem Biophys Res Commun 336: 1056-1061
    • (2005) Biochem Biophys Res Commun , vol.336 , pp. 1056-1061
    • Levitt, R.J.1
  • 20
    • 34249804521 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor binding protein-2(IGFBP-2) by MCF-7 breast cancer cells is regulated through the P13-kinase/AKT/mTOR pathway
    • Martin JL and Baxter RC (2007) Expression of insulin-like growth factor binding protein-2(IGFBP-2) by MCF-7 breast cancer cells is regulated through the P13-kinase/AKT/mTOR pathway. Endocrinology 148: 2532-2541
    • (2007) Endocrinology , vol.148 , pp. 2532-2541
    • Martin, J.L.1    Baxter, R.C.2
  • 21
    • 34248363956 scopus 로고    scopus 로고
    • (2607) Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and P13K/Akt pathway activation in glioblastoma and prostate cancer
    • Mehrian-Shai R et al. (2607) Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and P13K/Akt pathway activation in glioblastoma and prostate cancer. Proc Natl Acad Sci USA 104: 5563-5568
    • Proc Natl Acad Sci USA , vol.104 , pp. 5563-5568
    • Mehrian-Shai, R.1
  • 22
    • 0033621042 scopus 로고    scopus 로고
    • The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region
    • Georgescu MM et al. (1999) The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region. Proc Natl Acad Sci USA 96: 10182-10187
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10182-10187
    • Georgescu, M.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.