-
1
-
-
0028881603
-
The pax3-fkhr fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than pax3
-
W.J. Fredericks The pax3-fkhr fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than pax3 Mol. Cell. Biol. 15 1995 1522 1535
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1522-1535
-
-
Fredericks, W.J.1
-
2
-
-
0028867940
-
Structural characterization of the fkhr gene and its rearrangement in alveolar rhabdomyosarcoma
-
R.J. Davis Structural characterization of the fkhr gene and its rearrangement in alveolar rhabdomyosarcoma Hum. Mol. Genet. 4 1995 2355 2362
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 2355-2362
-
-
Davis, R.J.1
-
3
-
-
0035019007
-
Identification and characterization of members of the fkhr (FoxO) subclass of winged-helix transcription factors in the mouse
-
W. Biggs Identification and characterization of members of the fkhr (FoxO) subclass of winged-helix transcription factors in the mouse Mamm. Genome 12 2001 416 425
-
(2001)
Mamm. Genome
, vol.12
, pp. 416-425
-
-
Biggs, W.1
-
4
-
-
0141481091
-
FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics
-
F.M. Jacobs FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics J. Biol. Chem. 278 2003 35959 35967
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35959-35967
-
-
Jacobs, F.M.1
-
5
-
-
2342445654
-
Negative regulation of forkhead transcription factor afx (FOXO4) by CBP-induced acetylation
-
M. Fukuoka Negative regulation of forkhead transcription factor afx (FOXO4) by CBP-induced acetylation Int. J. Mol. Med. 12 2003 503 508
-
(2003)
Int. J. Mol. Med.
, vol.12
, pp. 503-508
-
-
Fukuoka, M.1
-
6
-
-
12144290563
-
Stress-dependent regulation of FoxO transcription factors by the Sirt1 deacetylase
-
A. Brunet Stress-dependent regulation of FoxO transcription factors by the Sirt1 deacetylase Science 303 2004 2011 2015
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
-
7
-
-
1342264308
-
Mammalian Sirt1 represses forkhead transcription factors
-
M.C. Motta Mammalian Sirt1 represses forkhead transcription factors Cell 116 2004 551 563
-
(2004)
Cell
, vol.116
, pp. 551-563
-
-
Motta, M.C.1
-
8
-
-
3042750643
-
Silent information regulator 2 potentiates FOXO1-mediated transcription through its deacetylase activity
-
H. Daitoku Silent information regulator 2 potentiates FOXO1-mediated transcription through its deacetylase activity Proc. Natl. Acad. Sci. U. S. A. 101 2004 10042 10047
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 10042-10047
-
-
Daitoku, H.1
-
9
-
-
3142742707
-
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(Sirt1)
-
A. van der Horst FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(Sirt1) J. Biol. Chem. 279 2004 28873 28879
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28873-28879
-
-
Van Der Horst, A.1
-
10
-
-
85047695408
-
Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells
-
D.L. Mahmud Phosphorylation of forkhead transcription factors by erythropoietin and stem cell factor prevents acetylation and their interaction with coactivator p300 in erythroid progenitor cells Oncogene 21 2002 1556 1562
-
(2002)
Oncogene
, vol.21
, pp. 1556-1562
-
-
Mahmud, D.L.1
-
11
-
-
0035846601
-
Regulation of c. elegans DAF-16 and its human ortholog fkhrl1 by the DAF-2 insulin-like signaling pathway
-
R.Y. Lee Regulation of c. elegans DAF-16 and its human ortholog fkhrl1 by the DAF-2 insulin-like signaling pathway Curr. Biol. 11 2001 1950 1957
-
(2001)
Curr. Biol.
, vol.11
, pp. 1950-1957
-
-
Lee, R.Y.1
-
12
-
-
0030659557
-
The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in c. elegans
-
S. Ogg The fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in c. elegans Nature 389 1997 994 999
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
-
13
-
-
0042161896
-
Control of cell number by Drosophila FoxO: Downstream and feedback regulation of the insulin receptor pathway
-
O. Puig Control of cell number by Drosophila FoxO: downstream and feedback regulation of the insulin receptor pathway Genes Dev. 17 2003 2006 2020
-
(2003)
Genes Dev.
, vol.17
, pp. 2006-2020
-
-
Puig, O.1
-
14
-
-
2942689828
-
Expression of Drosophila FoxO regulates growth and can phenocopy starvation
-
J.M. Kramer Expression of Drosophila FoxO regulates growth and can phenocopy starvation BMC Dev. Biol. 3 2003 5
-
(2003)
BMC Dev. Biol.
, vol.3
, pp. 5
-
-
Kramer, J.M.1
-
15
-
-
0242539698
-
The Drosophila forkhead transcription factor FoxO mediates the reduction in cell number associated with reduced insulin signaling
-
M.A. Junger The Drosophila forkhead transcription factor FoxO mediates the reduction in cell number associated with reduced insulin signaling J. Biol. 2 2003 20
-
(2003)
J. Biol.
, vol.2
, pp. 20
-
-
Junger, M.A.1
-
16
-
-
0036787607
-
Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor FOXO1
-
J. Nakae Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor FOXO1 Nat. Genet. 32 2002 245 253
-
(2002)
Nat. Genet.
, vol.32
, pp. 245-253
-
-
Nakae, J.1
-
17
-
-
1542267804
-
Disruption of forkhead transcription factor (FoxO) family members in mice reveals their functional diversification
-
T. Hosaka Disruption of forkhead transcription factor (FoxO) family members in mice reveals their functional diversification Proc. Natl. Acad. Sci. U. S. A. 101 2004 2975 2980
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 2975-2980
-
-
Hosaka, T.1
-
18
-
-
0037237279
-
The forkhead transcription factor FOXO1 regulates adipocyte differentiation
-
J. Nakae The forkhead transcription factor FOXO1 regulates adipocyte differentiation Dev. Cell 4 2003 119 129
-
(2003)
Dev. Cell
, vol.4
, pp. 119-129
-
-
Nakae, J.1
-
19
-
-
0036950665
-
The forkhead transcription factor FOXO1 links insulin signaling to PDX1 regulation of pancreatic β cell growth
-
T. Kitamura The forkhead transcription factor FOXO1 links insulin signaling to PDX1 regulation of pancreatic β cell growth J. Clin. Invest. 110 2002 1839 1847
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1839-1847
-
-
Kitamura, T.1
-
20
-
-
0038152845
-
Suppression of ovarian follicle activation in mice by the transcription factor FOXO3a
-
D.H. Castrillon Suppression of ovarian follicle activation in mice by the transcription factor FOXO3a Science 301 2003 215 218
-
(2003)
Science
, vol.301
, pp. 215-218
-
-
Castrillon, D.H.1
-
21
-
-
2942726155
-
The ins and outs of FoxO shuttling: Mechanisms of FoxO translocation and transcriptional regulation
-
L.P. Van Der Heide The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation Biochem. J. 380 2004 297 309
-
(2004)
Biochem. J.
, vol.380
, pp. 297-309
-
-
Van Der Heide, L.P.1
-
22
-
-
0034161544
-
Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR
-
J. Nakae Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR EMBO J. 19 2000 989 996
-
(2000)
EMBO J.
, vol.19
, pp. 989-996
-
-
Nakae, J.1
-
23
-
-
0035868368
-
Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting
-
G. Rena Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting Biochem. J. 354 2001 605 612
-
(2001)
Biochem. J.
, vol.354
, pp. 605-612
-
-
Rena, G.1
-
24
-
-
0033546192
-
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence
-
S. Guo Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence J. Biol. Chem. 274 1999 17184 17192
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17184-17192
-
-
Guo, S.1
-
25
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor
-
A. Brunet Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor Cell 96 1999 857 868
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
-
26
-
-
0035918148
-
Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways
-
C.M. Cahill Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways J. Biol. Chem. 276 2001 13402 13410
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 13402-13410
-
-
Cahill, C.M.1
-
27
-
-
0346963162
-
Two 14-3-3 binding motifs are required for stable association of forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding
-
T. Obsil Two 14-3-3 binding motifs are required for stable association of forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding Biochemistry 42 2003 15264 15272
-
(2003)
Biochemistry
, vol.42
, pp. 15264-15272
-
-
Obsil, T.1
-
28
-
-
0035034038
-
Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX
-
A.M. Brownawell Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX Mol. Cell. Biol. 21 2001 3534 3546
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3534-3546
-
-
Brownawell, A.M.1
-
29
-
-
0037018148
-
14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport
-
A. Brunet 14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport J. Cell Biol. 156 2002 817 828
-
(2002)
J. Cell Biol.
, vol.156
, pp. 817-828
-
-
Brunet, A.1
-
30
-
-
0036566003
-
Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion
-
G. Rena Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion EMBO J. 21 2002 2263 2271
-
(2002)
EMBO J.
, vol.21
, pp. 2263-2271
-
-
Rena, G.1
-
31
-
-
12944335299
-
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HEPG2 cells
-
N. Nasrin DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HEPG2 cells Proc. Natl. Acad. Sci. U. S. A. 97 2000 10412 10417
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 10412-10417
-
-
Nasrin, N.1
-
32
-
-
0034051227
-
Acetylation of histones and transcription-related factors
-
D.E. Sterner, and S.L. Berger Acetylation of histones and transcription-related factors Microbiol. Mol. Biol. Rev. 64 2000 435 459
-
(2000)
Microbiol. Mol. Biol. Rev.
, vol.64
, pp. 435-459
-
-
Sterner, D.E.1
Berger, S.L.2
-
33
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
G. Blander, and L. Guarente The Sir2 family of protein deacetylases Annu. Rev. Biochem. 73 2004 417 435
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
34
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
H.A. Tissenbaum, and L. Guarente Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans Nature 410 2001 227 230
-
(2001)
Nature
, vol.410
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
35
-
-
1842475551
-
Protein kinase Bα inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FoxO transcription factors
-
H.S. Kwon Protein kinase Bα inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FoxO transcription factors Diabetes 53 2004 899 910
-
(2004)
Diabetes
, vol.53
, pp. 899-910
-
-
Kwon, H.S.1
-
36
-
-
0242552509
-
The proline repeat domain of p53 binds directly to the transcriptional coactivator p300 and allosterically controls DNA-dependent acetylation of p53
-
D. Dornan The proline repeat domain of p53 binds directly to the transcriptional coactivator p300 and allosterically controls DNA-dependent acetylation of p53 Mol. Cell. Biol. 23 2003 8846 8861
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8846-8861
-
-
Dornan, D.1
-
37
-
-
0036651790
-
A novel mechanism of gene regulation and tumor suppression by the transcription factor fkhr
-
S. Ramaswamy A novel mechanism of gene regulation and tumor suppression by the transcription factor fkhr Cancer Cell 2 2002 81 91
-
(2002)
Cancer Cell
, vol.2
, pp. 81-91
-
-
Ramaswamy, S.1
-
38
-
-
1442330508
-
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo
-
J. Luo Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo Proc. Natl. Acad. Sci. U. S. A. 101 2004 2259 2264
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 2259-2264
-
-
Luo, J.1
-
39
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the Sirt1 deacetylase
-
H.Y. Cohen Calorie restriction promotes mammalian cell survival by inducing the Sirt1 deacetylase Science 305 2004 390 392
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
-
40
-
-
0347128279
-
Calorie restriction extends yeast life span by lowering the level of NADH
-
S.J. Lin Calorie restriction extends yeast life span by lowering the level of NADH Genes Dev. 18 2004 12 16
-
(2004)
Genes Dev.
, vol.18
, pp. 12-16
-
-
Lin, S.J.1
|