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Volumn 111, Issue 6, 2014, Pages 2349-2354

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells

Author keywords

Imbruvica; PCI 32765; Translational research

Indexed keywords

IMBRUVICA; PCI-32765; TRANSLATIONAL RESEARCH;

EID: 84893825160     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1311846111     Document Type: Article
Times cited : (319)

References (52)
  • 1
    • 77957200763 scopus 로고    scopus 로고
    • Long-term outcome of patients in the LNH-98. 5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: A study by the Groupe d'Etudes des Lymphomes de l'Adulte
    • Coiffier B, et al. (2010) Long-term outcome of patients in the LNH-98.5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: A study by the Groupe d'Etudes des Lymphomes de l'Adulte. Blood 116(12):2040-2045.
    • (2010) Blood , vol.116 , Issue.12 , pp. 2040-2045
    • Coiffier, B.1
  • 2
    • 84863651163 scopus 로고    scopus 로고
    • Combinatorial drug therapy for cancer in the post-genomic era
    • Al-Lazikani B, Banerji U, Workman P (2012) Combinatorial drug therapy for cancer in the post-genomic era. Nat Biotechnol 30(7):679-692.
    • (2012) Nat Biotechnol , vol.30 , Issue.7 , pp. 679-692
    • Al-Lazikani, B.1    Banerji, U.2    Workman, P.3
  • 3
    • 78049457409 scopus 로고    scopus 로고
    • Utilizing targeted cancer therapeutic agents in combination: Novel approaches and urgent requirements
    • Kummar S, et al. (2010) Utilizing targeted cancer therapeutic agents in combination: Novel approaches and urgent requirements. Nat Rev Drug Discov 9(11):843-856.
    • (2010) Nat Rev Drug Discov , vol.9 , Issue.11 , pp. 843-856
    • Kummar, S.1
  • 4
    • 84859169877 scopus 로고    scopus 로고
    • The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
    • Barretina J, et al. (2012) The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 483(7391):603-607.
    • (2012) Nature , vol.483 , Issue.7391 , pp. 603-607
    • Barretina, J.1
  • 5
    • 84859187259 scopus 로고    scopus 로고
    • Systematic identification of genomic markers of drug sensitivity in cancer cells
    • Garnett MJ, et al. (2012) Systematic identification of genomic markers of drug sensitivity in cancer cells. Nature 483(7391):570-575.
    • (2012) Nature , vol.483 , Issue.7391 , pp. 570-575
    • Garnett, M.J.1
  • 6
    • 58149398623 scopus 로고    scopus 로고
    • Translation of the Philadelphia chromosome into therapy for CML
    • Druker BJ (2008) Translation of the Philadelphia chromosome into therapy for CML. Blood 112(13):4808-4817.
    • (2008) Blood , vol.112 , Issue.13 , pp. 4808-4817
    • Druker, B.J.1
  • 7
    • 84868224906 scopus 로고    scopus 로고
    • Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations
    • Flaherty KT, et al. (2012) Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations. N Engl J Med 367(18):1694-1703.
    • (2012) N Engl J Med , vol.367 , Issue.18 , pp. 1694-1703
    • Flaherty, K.T.1
  • 9
    • 84875185728 scopus 로고    scopus 로고
    • Targeting pathological B cell receptor signalling in lymphoid malignancies
    • Young RM, Staudt LM (2013) Targeting pathological B cell receptor signalling in lymphoid malignancies. Nat Rev Drug Discov 12(3):229-243.
    • (2013) Nat Rev Drug Discov , vol.12 , Issue.3 , pp. 229-243
    • Young, R.M.1    Staudt, L.M.2
  • 10
    • 73849145729 scopus 로고    scopus 로고
    • Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
    • Davis RE, et al. (2010) Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma. Nature 463(7277):88-92.
    • (2010) Nature , vol.463 , Issue.7277 , pp. 88-92
    • Davis, R.E.1
  • 11
    • 41149136296 scopus 로고    scopus 로고
    • Oncogenic CARD11 mutations in human diffuse large B cell lymphoma
    • Lenz G, et al. (2008) Oncogenic CARD11 mutations in human diffuse large B cell lymphoma. Science 319(5870):1676-1679.
    • (2008) Science , vol.319 , Issue.5870 , pp. 1676-1679
    • Lenz, G.1
  • 12
    • 79551686422 scopus 로고    scopus 로고
    • Oncogenically active MYD88 mutations in human lymphoma
    • Ngo VN, et al. (2011) Oncogenically active MYD88 mutations in human lymphoma. Nature 470(7332):115-119.
    • (2011) Nature , vol.470 , Issue.7332 , pp. 115-119
    • Ngo, V.N.1
  • 13
    • 84862152044 scopus 로고    scopus 로고
    • Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma
    • Yang Y, et al. (2012) Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma. Cancer Cell 21(6):723-737.
    • (2012) Cancer Cell , vol.21 , Issue.6 , pp. 723-737
    • Yang, Y.1
  • 14
    • 43549097394 scopus 로고    scopus 로고
    • Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-κB pathways in subtypes of diffuse large B-cell lymphoma
    • Lam LT, et al. (2008) Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-κB pathways in subtypes of diffuse large B-cell lymphoma. Blood 111(7):3701-3713.
    • (2008) Blood , vol.111 , Issue.7 , pp. 3701-3713
    • Lam, L.T.1
  • 15
    • 0038610570 scopus 로고    scopus 로고
    • Systematic discovery of multicomponent therapeutics
    • Borisy AA, et al. (2003) Systematic discovery of multicomponent therapeutics. Proc Natl Acad Sci USA 100(13):7977-7982.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.13 , pp. 7977-7982
    • Borisy, A.A.1
  • 16
    • 81355127286 scopus 로고    scopus 로고
    • Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing
    • Small BG, et al. (2011) Efficient discovery of anti-inflammatory small-molecule combinations using evolutionary computing. Nat Chem Biol 7(12):902-908.
    • (2011) Nat Chem Biol , vol.7 , Issue.12 , pp. 902-908
    • Small, B.G.1
  • 17
    • 67650488269 scopus 로고    scopus 로고
    • Synergistic drug combinations tend to improve therapeutically relevant selectivity
    • Lehár J, et al. (2009) Synergistic drug combinations tend to improve therapeutically relevant selectivity. Nat Biotechnol 27(7):659-666.
    • (2009) Nat Biotechnol , vol.27 , Issue.7 , pp. 659-666
    • Lehár, J.1
  • 19
    • 0842279636 scopus 로고    scopus 로고
    • Transfer of low nanoliter volumes between microplates using focused acoustics-Automation considerations
    • Ellson R, et al. (2003) Transfer of low nanoliter volumes between microplates using focused acoustics-Automation considerations. J Lab Auto 8(3):29-34.
    • (2003) J Lab Auto , vol.8 , Issue.3 , pp. 29-34
    • Ellson, R.1
  • 20
    • 84946384873 scopus 로고
    • The toxicity of poisons applied jointly
    • Bliss CI (1939) The toxicity of poisons applied jointly. Ann Appl Biol 26:585-615.
    • (1939) Ann Appl Biol , vol.26 , pp. 585-615
    • Bliss, C.I.1
  • 21
    • 4243191446 scopus 로고    scopus 로고
    • Isobolographic analysis for combinations of a full and partial agonist: Curved isoboles
    • Grabovsky Y, Tallarida RJ (2004) Isobolographic analysis for combinations of a full and partial agonist: Curved isoboles. J Pharmacol Exp Ther 310(3):981-986.
    • (2004) J Pharmacol Exp Ther , vol.310 , Issue.3 , pp. 981-986
    • Grabovsky, Y.1    Tallarida, R.J.2
  • 22
    • 33847643207 scopus 로고    scopus 로고
    • Chemical combination effects predict connectivity in biological systems
    • Lehár J, et al. (2007) Chemical combination effects predict connectivity in biological systems. Mol Syst Biol 3:80.
    • (2007) Mol Syst Biol , vol.3 , pp. 80
    • Lehár, J.1
  • 23
    • 80855124963 scopus 로고    scopus 로고
    • Systematic exploration of synergistic drug pairs
    • Cokol M, et al. (2011) Systematic exploration of synergistic drug pairs. Mol Syst Biol 7:544.
    • (2011) Mol Syst Biol , vol.7 , pp. 544
    • Cokol, M.1
  • 24
    • 0035905313 scopus 로고    scopus 로고
    • Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells
    • Davis RE, Brown KD, Siebenlist U, Staudt LM (2001) Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells. J Exp Med 194(12):1861-1874.
    • (2001) J Exp Med , vol.194 , Issue.12 , pp. 1861-1874
    • Davis, R.E.1    Brown, K.D.2    Siebenlist, U.3    Staudt, L.M.4
  • 25
    • 1042268879 scopus 로고    scopus 로고
    • Gene expression profiling of diffuse large B-cell lymphoma
    • Rosenwald A, Staudt LM (2003) Gene expression profiling of diffuse large B-cell lymphoma. Leuk Lymphoma 44(Suppl 3):S41-S47.
    • (2003) Leuk Lymphoma , vol.44 , Issue.SUPPL. 3
    • Rosenwald, A.1    Staudt, L.M.2
  • 26
    • 66649127621 scopus 로고    scopus 로고
    • Mutations of multiple genes cause deregulation of NFkappaB in diffuse large B-cell lymphoma
    • Compagno M, et al. (2009) Mutations of multiple genes cause deregulation of NFkappaB in diffuse large B-cell lymphoma. Nature 459(7247):717-721.
    • (2009) Nature , vol.459 , Issue.7247 , pp. 717-721
    • Compagno, M.1
  • 28
    • 77649189887 scopus 로고    scopus 로고
    • Identification of known drugs that act as inhibitors of NFkappaB signaling and their mechanism of action
    • Miller SC, et al. (2010) Identification of known drugs that act as inhibitors of NFkappaB signaling and their mechanism of action. Biochem Pharmacol 79(9):1272-1280.
    • (2010) Biochem Pharmacol , vol.79 , Issue.9 , pp. 1272-1280
    • Miller, S.C.1
  • 29
    • 77950852364 scopus 로고    scopus 로고
    • Therapeutic efficacy of the pan-cdk inhibitor PHA-793887 in vitro and in vivo in engraftment and high-burden leukemia models
    • e2
    • Alzani R, et al. (2010) Therapeutic efficacy of the pan-cdk inhibitor PHA-793887 in vitro and in vivo in engraftment and high-burden leukemia models. Exp Hematol 38(4):259-269, e2.
    • (2010) Exp Hematol , vol.38 , Issue.4 , pp. 259-269
    • Alzani, R.1
  • 30
    • 33751111683 scopus 로고    scopus 로고
    • Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IkappaB kinase (IKK)
    • Qing G, Yan P, Xiao G (2006) Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IkappaB kinase (IKK). Cell Res 16(11):895-901.
    • (2006) Cell Res , vol.16 , Issue.11 , pp. 895-901
    • Qing, G.1    Yan, P.2    Xiao, G.3
  • 31
    • 0028879819 scopus 로고
    • Role of transcriptional activation of i kappa B alpha in mediation of immunosuppression by glucocorticoids
    • Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS, Jr. (1995) Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270(5234):283-286.
    • (1995) Science , vol.270 , Issue.5234 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin Jr., A.S.4
  • 32
    • 78751483373 scopus 로고    scopus 로고
    • Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-kappaB signaling pathway
    • Jane EP, Premkumar DR, Pollack IF (2011) Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-kappaB signaling pathway. Mol Cancer Ther 10(1):198-208.
    • (2011) Mol Cancer Ther , vol.10 , Issue.1 , pp. 198-208
    • Jane, E.P.1    Premkumar, D.R.2    Pollack, I.F.3
  • 33
    • 33845976705 scopus 로고    scopus 로고
    • Triterpenoid CDDO-Me blocks the NF-kappaB pathway by direct inhibition of IKKbeta on Cys-179
    • Ahmad R, Raina D, Meyer C, Kharbanda S, Kufe D (2006) Triterpenoid CDDO-Me blocks the NF-kappaB pathway by direct inhibition of IKKbeta on Cys-179. J Biol Chem 281(47):35764-35769.
    • (2006) J Biol Chem , vol.281 , Issue.47 , pp. 35764-35769
    • Ahmad, R.1    Raina, D.2    Meyer, C.3    Kharbanda, S.4    Kufe, D.5
  • 34
    • 33947530134 scopus 로고    scopus 로고
    • Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity
    • Kaileh M, et al. (2007) Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity. J Biol Chem 282(7):4253-4264.
    • (2007) J Biol Chem , vol.282 , Issue.7 , pp. 4253-4264
    • Kaileh, M.1
  • 35
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, et al. (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403(6769):503-511.
    • (2000) Nature , vol.403 , Issue.6769 , pp. 503-511
    • Alizadeh, A.A.1
  • 36
    • 51649111684 scopus 로고    scopus 로고
    • Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways
    • Lenz G, et al. (2008) Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways. Proc Natl Acad Sci USA 105(36):13520-13525.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.36 , pp. 13520-13525
    • Lenz, G.1
  • 37
    • 78651066552 scopus 로고    scopus 로고
    • Critical role of PI3K signaling for NF-kappaB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells
    • Kloo B, et al. (2011) Critical role of PI3K signaling for NF-kappaB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells. Proc Natl Acad Sci USA 108(1):272-277.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.1 , pp. 272-277
    • Kloo, B.1
  • 38
    • 78751553221 scopus 로고    scopus 로고
    • CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability
    • Lannutti BJ, et al. (2011) CAL-101, a p110δ selective phosphatidylinositol-3-kinase inhibitor for the treatment of B-cell malignancies, inhibits PI3K signaling and cellular viability. Blood 117(2):591-594.
    • (2011) Blood , vol.117 , Issue.2 , pp. 591-594
    • Lannutti, B.J.1
  • 39
    • 84856826293 scopus 로고    scopus 로고
    • Identification and characterization of NVP-BKM120, an orally available pan-class i PI3-kinase inhibitor
    • Maira S-M, et al. (2012) Identification and characterization of NVP-BKM120, an orally available pan-class I PI3-kinase inhibitor. Mol Cancer Ther 11(2):317-328.
    • (2012) Mol Cancer Ther , vol.11 , Issue.2 , pp. 317-328
    • Maira, S.-M.1
  • 40
    • 51049109033 scopus 로고    scopus 로고
    • Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
    • Maira S-M, et al. (2008) Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity. Mol Cancer Ther 7(7):1851-1863.
    • (2008) Mol Cancer Ther , vol.7 , Issue.7 , pp. 1851-1863
    • Maira, S.-M.1
  • 41
    • 83355163329 scopus 로고    scopus 로고
    • GDC-0980 is a novel class i PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway
    • Wallin JJ, et al. (2011) GDC-0980 is a novel class I PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway. Mol Cancer Ther 10(12):2426-2436.
    • (2011) Mol Cancer Ther , vol.10 , Issue.12 , pp. 2426-2436
    • Wallin, J.J.1
  • 42
    • 77954615408 scopus 로고    scopus 로고
    • MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo
    • Hirai H, et al. (2010) MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo. Mol Cancer Ther 9(7):1956-1967.
    • (2010) Mol Cancer Ther , vol.9 , Issue.7 , pp. 1956-1967
    • Hirai, H.1
  • 44
    • 84863781222 scopus 로고    scopus 로고
    • Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration
    • Hoellenriegel J, et al. (2012) Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration. Leukemia 26(7):1576-1583.
    • (2012) Leukemia , vol.26 , Issue.7 , pp. 1576-1583
    • Hoellenriegel, J.1
  • 45
    • 20444486559 scopus 로고    scopus 로고
    • An inhibitor of Bcl-2 family proteins induces regression of solid tumours
    • Oltersdorf T, et al. (2005) An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 435(7042):677-681.
    • (2005) Nature , vol.435 , Issue.7042 , pp. 677-681
    • Oltersdorf, T.1
  • 46
    • 84873540049 scopus 로고    scopus 로고
    • ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
    • Souers AJ, et al. (2013) ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets. Nat Med 19(2):202-208.
    • (2013) Nat Med , vol.19 , Issue.2 , pp. 202-208
    • Souers, A.J.1
  • 47
    • 84860573088 scopus 로고    scopus 로고
    • A Cancer and Leukemia Group B multi-center study of DA-EPOCH-rituximab in untreated diffuse large B-cell lymphoma with analysis of outcome by molecular subtype
    • Cancer Leukemia Group B
    • Wilson WH, et al.; Cancer Leukemia Group B (2012) A Cancer and Leukemia Group B multi-center study of DA-EPOCH-rituximab in untreated diffuse large B-cell lymphoma with analysis of outcome by molecular subtype. Haematologica 97(5):758-765.
    • (2012) Haematologica , vol.97 , Issue.5 , pp. 758-765
    • Wilson, W.H.1
  • 48
    • 84877597290 scopus 로고    scopus 로고
    • Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) has significant activity in patients with relapsed/refractory B cell malignancies
    • Advani RH, et al. (2012) Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) has significant activity in patients with relapsed/refractory B cell malignancies. J Clin Oncol 42:7906-7915.
    • (2012) J Clin Oncol , vol.42 , pp. 7906-7915
    • Advani, R.H.1
  • 49
    • 84874585216 scopus 로고    scopus 로고
    • The Bruton's tyrosine kinase (BTK) inhibitor, ibrutinib (PCI-32765), has preferential activity in the ABC subtype of relapsed/refractory de novo diffuse large B cell lymphoma (DLBCL): Interim results of a multicenter, open-label, phase 2 study
    • December (American Society of Hematology, Atlanta, GA), abstr 686
    • Wilson WH, et al. The Bruton's tyrosine kinase (BTK) inhibitor, ibrutinib (PCI-32765), has preferential activity in the ABC subtype of relapsed/refractory de novo diffuse large B cell lymphoma (DLBCL): Interim results of a multicenter, open-label, phase 2 study. 54th Annual Meeting and Exposition, December 2012 (American Society of Hematology, Atlanta, GA), abstr 686.
    • (2012) 54th Annual Meeting and Exposition
    • Wilson, W.H.1
  • 50
    • 84907280382 scopus 로고    scopus 로고
    • The Bruton's tyrosine kinase (BTK) inhibitor ibrutinib (PCI-32765) promotes high response rate, durable remissions, and is tolerable in treatment naïve (TN) and relapsed or refractory (RR) chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) patients including patients with high-risk (HR) disease: New and updated results of 116 patients in a phase Ib/II study
    • December 2012 (American Society of Hematology, Atlanta, GA), abstr 189
    • Byrd JC, et al. (2012) The Bruton's tyrosine kinase (BTK) inhibitor ibrutinib (PCI-32765) promotes high response rate, durable remissions, and is tolerable in treatment naïve (TN) and relapsed or refractory (RR) chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) patients including patients with high-risk (HR) disease: New and updated results of 116 patients in a phase Ib/II study. 54th Annual Meeting and Exposition, December 2012 (American Society of Hematology, Atlanta, GA), abstr 189.
    • (2012) 54th Annual Meeting and Exposition
    • Byrd, J.C.1
  • 51
    • 78649630259 scopus 로고    scopus 로고
    • Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: A phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity
    • Wilson WH, et al. (2010) Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: A phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity. Lancet Oncol 11(12):1149-1159.
    • (2010) Lancet Oncol , vol.11 , Issue.12 , pp. 1149-1159
    • Wilson, W.H.1
  • 52
    • 84858722471 scopus 로고    scopus 로고
    • DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out
    • McCool KW, Miyamoto S (2012) DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out. Immunol Rev 246(1):311-326.
    • (2012) Immunol Rev , vol.246 , Issue.1 , pp. 311-326
    • McCool, K.W.1    Miyamoto, S.2


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