Emulsion microgel particles: Novel encapsulation strategy for lipophilic molecules

Trends in Food Science and Technology

Volumn 55, Issue , 2016, Pages 98-108

  Torres, Ophelie ^a   Murray, Brent ^a   Sarkar, Anwesha ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Emulsion microgel particle; Filler matrix interaction; Matrix erosion; Swelling; Whey protein

Indexed keywords

EROSION; ESSENTIAL OILS; FATTY ACIDS; FILLERS; GELS; MOLECULES; OILS AND FATS; PROTEINS; SWELLING;

CONTROLLED DELIVERY; FILLER-MATRIX INTERACTION; MATRIX EROSION; MICROGEL PARTICLES; PERSONAL CARE INDUSTRY; PROCESSING CONDITION; TOP DOWN APPROACHES; WHEY PROTEINS;

EMULSIFICATION;

EID: 84979200318     PISSN: 09242244     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tifs.2016.07.006     Document Type: Review

References (100)

1. van Aken, G.A., Oliver, L., Scholten, E., Rheological effect of particle clustering in gelled dispersions. Food Hydrocolloids 48 (2015), 102–109.
2. Alting, A.C., Hamer, R.J., de Kruif, C.G., Visschers, R.W., Cold-set globular protein gels: Interactions, structure and rheology as a function of protein concentration. Journal of Agricultural and Food Chemistry 51 (2003), 3150–3156.
3. Anton, M., Le Denmat, M., Beaumal, V., Pilet, P., Filler effects of oil droplets on the rheology of heat-set emulsion gels prepared with egg yolk and egg yolk fractions. Colloids and Surfaces B: Biointerfaces 21 (2001), 137–147.
4. Atyabi, F., Manoochehri, S., Moghadam, S.H., Dinarvand, R., Cross-linked starch microspheres: Effect of cross-linking condition on the microsphere characteristics. Archives of Pharmacal Research 29 (2006), 1179–1186.
5. Augustin, M.A., Sanguansri, L., 2-Challenges in developing delivery systems for food additives, nutraceuticals and dietary supplements A2-Garti, Nissim. McClements, D.J., (eds.) Encapsulation technologies and delivery systems for food ingredients and nutraceuticals, 2012, Woodhead Publishing, 19–48.
6. Ballauff, M., Lu, Y., “Smart” nanoparticles: Preparation, characterization and applications. Polymer 48 (2007), 1815–1823.
7. Bao, J., Xing, J., Phillips, D.L., Corke, H., Physical properties of octenyl succinic anhydride modified rice, wheat, and potato starches. Journal of Agricultural and Food Chemistry 51 (2003), 2283–2287.
8. Beaulieu, L., Savoie, L., Paquin, P., Subirade, M., Elaboration and characterization of whey protein beads by an emulsification/cold gelation process: Application for the protection of retinol. Biomacromolecules 3 (2002), 239–248.
9. Bhosale, R., Singhal, R., Effect of octenylsuccinylation on physicochemical and functional properties of waxy maize and amaranth starches. Carbohydrate Polymers 68 (2007), 447–456.
10. Boutin, C., Giroux, H.J., Paquin, P., Britten, M., Characterization and acid-induced gelation of butter oil emulsions produced from heated whey protein dispersions. International Dairy Journal 17 (2007), 696–703.
11. Briuglia, M., Urquhart, A.J., Lamprou, D.A., Sustained and controlled release of lipophilic drugs from a self-assembling amphiphilic peptide hydrogel. International Journal of Pharmaceutics 474 (2014), 103–111.
12. Bryant, C.M., McClements, D.J., Molecular basis of protein functionality with special consideration of cold-set gels derived from heat-denatured whey. Trends in Food Science & Technology 9 (1998), 143–151.
13. Chen, J.S., Dickinson, E., Viscoelastic properties of heat-set whey protein emulsion gels. Journal of Texture Studies 29 (1998), 285–304.
14. Chen, J.S., Dickinson, E., Effect of surface character of filler particles on rheology of heat-set whey protein emulsion gels. Colloids and Surfaces B-Biointerfaces 12 (1999), 373–381.
15. Chen, J.S., Dickinson, E., Interfacial ageing effect on the rheology of a heat-set protein emulsion gel. Food Hydrocolloids 13 (1999), 363–369.
16. Chen, J.S., Dickinson, E., Langton, M., Hermansson, A.M., Mechanical properties and microstructure of heat-set whey protein emulsion gels: Effect of emulsifiers. Lebensmittel-Wissenschaft Und-Technologie-Food Science and Technology 33 (2000), 299–307.
17. Chen, J.S., Dickinson, E., Lee, H.S., Lee, W.P., Protein-based emulsion gels: Effects of interfacial properties and temperature. Dickinson, E., Miller, R., (eds.) Food colloids: Fundamentals of formulation, 2001, Royal Soc Chemistry, Cambridge, 384–391.
18. Ching, S.H., Bansal, N., Bhandari, B., Physical stability of emulsion encapsulated in alginate microgel particles by the impinging aerosol technique. Food Research International 75 (2015), 182–193.
19. Ching, S.H., Bansal, N., Bhandari, B., Rheology of emulsion-filled alginate microgel suspensions. Food Research International 80 (2016), 50–60.
20. Chivero, P., Gohtani, S., Yoshii, H., Nakamura, A., Assessment of soy soluble polysaccharide, gum arabic and OSA-Starch as emulsifiers for mayonnaise-like emulsions. LWT - Food Science and Technology 69 (2016), 59–66.
21. Chung, C., Degner, B., Decker, E.A., McClements, D.J., Oil-filled hydrogel particles for reduced-fat food applications: Fabrication, characterization, and properties. Innovative Food Science & Emerging Technologies 20 (2013), 324–334.
22. Dang, H.V., Loisel, C., Desrumaux, A., Doublier, J.L., Rheology and microstructure of cross-linked waxy maize starch/whey protein suspensions. Food Hydrocolloids 23 (2009), 1678–1686.
23. Dickinson, E., Structure formation in casein-based gels, foams, and emulsions. Colloids and Surfaces A: Physicochemical and Engineering Aspects 288 (2006), 3–11.
24. Dickinson, E., Emulsion gels: The structuring of soft solids with protein-stabilized oil droplets. Food Hydrocolloids 28 (2012), 224–241.
25. Dickinson, E., Microgels - An alternative colloidal ingredient for stabilization of food emulsions. Trends in Food Science & Technology 43 (2015), 178–188.
26. Dickinson, E., Chen, J.S., Heat-Set Whey Protein Emulsion Gels: Role of Active and Inactive Filler Particles. Journal of Dispersion Science and Technology 20 (1999), 197–213.
27. Dissanayake, M., Ramchandran, L., Donkor, O.N., Vasiljevic, T., Denaturation of whey proteins as a function of heat, pH and protein concentration. International Dairy Journal 31 (2013), 93–99.
28. Domian, E., Brynda-Kopytowska, A., Oleksza, K., Rheological properties and physical stability of o/w emulsions stabilized by OSA starch with trehalose. Food Hydrocolloids 44 (2015), 49–58.
29. Egan, T., Jacquier, J.C., Rosenberg, Y., Rosenberg, M., Cold-set whey protein microgels for the stable immobilization of lipids. Food Hydrocolloids 31 (2013), 317–324.
30. Egan, T., O'Riordan, D., O'Sullivan, M., Jacquier, J.C., Cold-set whey protein microgels as pH modulated immobilisation matrices for charged bioactives. Food Chemistry 156 (2014), 197–203.
31. Ettelaie, R., Holmes, M., Chen, J., Farshchi, A., Steric stabilising properties of hydrophobically modified starch: Amylose vs. amylopectin. Food Hydrocolloids 58 (2016), 364–377.
32. Fitzsimons, S.M., Mulvihill, D.M., Morris, E.R., Segregative interactions between gelatin and polymerised whey protein. Food Hydrocolloids 22 (2008), 485–491.
33. Garrec, D.A., Norton, I.T., Understanding fluid gel formation and properties. Journal of Food Engineering 112 (2012), 175–182.
34. Gunasekaran, S., Ko, S., Xiao, L., Use of whey proteins for encapsulation and controlled delivery applications. Journal of Food Engineering 83 (2007), 31–40.
35. Gunasekaran, S., Xiao, L., Ould Eleya, M.M., Whey protein concentrate hydrogels as bioactive carriers. Journal of Applied Polymer Science 99 (2006), 2470–2476.
36. Harper, J.M., Clark, J.P., Food extrusion. C R C Critical Reviews in Food Science and Nutrition 11 (1979), 155–215.
37. Hongsprabhas, P., Barbut, S., Protein and salt effects on Ca2+-induced cold gelation of whey protein isolate. Journal of Food Science 62 (1997), 382–385.
38. Joye, I.J., McClements, D.J., Biopolymer-based nanoparticles and microparticles: Fabrication, characterization, and application. Current Opinion in Colloid & Interface Science 19 (2014), 417–427.
39. Kakran, M., Antipina, M.N., Emulsion-based techniques for encapsulation in biomedicine, food and personal care. Current Opinion in Pharmacology 18 (2014), 47–55.
40. Kananen, A., Savolainen, J., Mäkinen, J., Perttilä, U., Myllykoski, L., Pihlanto-Leppälä, A., Influence of chemical modification of whey protein conformation on hydrolysis with pepsin and trypsin. International Dairy Journal 10 (2000), 691–697.
41. Kawaguchi, H., Thermoresponsive microhydrogels: Preparation, properties and applications. Polymer International 63 (2014), 925–932.
42. Kerner, E.H., The elastic and thermo-elastic properties of composite media. Proceedings of the Physical Society. Section B, 69, 1956, 808.
43. Kuhn, K.R., Cavallieri, Â.L.F., Da Cunha, R.L., Cold-set whey protein gels induced by calcium or sodium salt addition. International Journal of Food Science & Technology 45 (2010), 348–357.
44. Liang, L., Leung Sok Line, V., Remondetto, G.E., Subirade, M., In vitro release of α-tocopherol from emulsion-loaded β-lactoglobulin gels. International Dairy Journal 20 (2010), 176–181.
45. Livney, Y.D., Milk proteins as vehicles for bioactives. Current Opinion in Colloid & Interface Science 15 (2010), 73–83.
46. Loveday, S.M., Sarkar, A., Singh, H., Innovative yoghurts: Novel processing technologies for improving acid milk gel texture. Trends in Food Science & Technology 33 (2013), 5–20.
47. Lucey, J.A., Singh, H., Formation and physical properties of acid milk gels: A review. Food Research International 30 (1997), 529–542.
48. Malone, M.E., Appelqvist, I.A.M., Gelled emulsion particles for the controlled release of lipophilic volatiles during eating. Journal of Controlled Release 90 (2003), 227–241.
49. Malone, M.E., Appelqvist, I.A.M., Norton, I.T., Oral behaviour of food hydrocolloids and emulsions. Part 2. Taste and aroma release. Food Hydrocolloids 17 (2003), 775–784.
50. Mao, L.K., Miao, S., Structuring food emulsions to improve nutrient delivery during digestion. Food Engineering Reviews 7 (2015), 439–451.
51. Matalanis, A., Jones, O.G., McClements, D.J., Structured biopolymer-based delivery systems for encapsulation, protection, and release of lipophilic compounds. Food Hydrocolloids 25 (2011), 1865–1880.
52. McClements, D.J., Mechanical particle fabrication methods. Nanoparticle- and microparticle-based delivery systems, 2014, CRC Press, 123–148.
53. McClements, D.J., Encapsulation, protection, and release of hydrophilic active components: Potential and limitations of colloidal delivery systems. Advances in Colloid and Interface Science 219 (2015), 27–53.
54. McClements, D.J., Li, Y., Structured emulsion-based delivery systems: Controlling the digestion and release of lipophilic food components. Advances in Colloid and Interface Science 159 (2010), 213–228.
55. McClements, D.J., Monahan, F.J., Kinsella, J.E., Effect of emulsion droplets on the rheology of whey-protein isolate gels. Journal of Texture Studies 24 (1993), 411–422.
56. Moakes, R.J.A., Sullo, A., Norton, I.T., Preparation and characterisation of whey protein fluid gels: The effects of shear and thermal history. Food Hydrocolloids 45 (2015), 227–235.
57. Moakes, R.J.A., Sullo, A., Norton, I.T., Preparation and rheological properties of whey protein emulsion fluid gels. RSC Advances 5 (2015), 60786–60795.
58. Monahan, F.J., McClements, D.J., German, J.B., Disulfide-mediated polymerization reactions and physical properties of heated WPI-stabilized emulsions. Journal of Food Science 61 (1996), 504–509.
59. Mun, S., Kim, Y.R., McClements, D.J., Control of beta-carotene bioaccessibility using starch-based filled hydrogels. Food Chemistry 173 (2015), 454–461.
60. Mun, S., Kim, Y.R., Shin, M., McClements, D.J., Control of lipid digestion and nutraceutical bioaccessibility using starch-based filled hydrogels: Influence of starch and surfactant type. Food Hydrocolloids 44 (2015), 380–389.
61. Nicolai, T., Britten, M., Schmitt, C., β-Lactoglobulin and WPI aggregates: Formation, structure and applications. Food Hydrocolloids 25 (2011), 1945–1962.
62. Oliver, L., Berndsen, L., van Aken, G.A., Scholten, E., Influence of droplet clustering on the rheological properties of emulsion-filled gels. Food Hydrocolloids 50 (2015), 74–83.
63. Oliver, L., Scholten, E., van Aken, G.A., Effect of fat hardness on large deformation rheology of emulsion-filled gels. Food Hydrocolloids 43 (2015), 299–310.
64. Ortega-Ojeda, F.E., Larsson, H., Eliasson, A., Gel formation in mixtures of hydrophobically modified potato and high amylopectin potato starch. Carbohydrate Polymers 59 (2005), 313–327.
65. Paulsson, M., Edsman, K., Controlled drug release from gels using lipophilic interactions of charged substances with surfactants and polymers. Journal of Colloid and Interface Science 248 (2002), 194–200.
66. Pizzoni, D., Compagnone, D., Di Natale, C., D'Alessandro, N., Pittia, P., Evaluation of aroma release of gummy candies added with strawberry flavours by gas-chromatography/mass-spectrometry and gas sensors arrays. Journal of Food Engineering 167 (2015), 77–86 Part A.
67. van der Poel, C., On the rheology of concentrated dispersions. Rheologica Acta 1 (1958), 198–205.
68. Puyol, P., Pérez, M.D., Horne, D.S., Heat-induced gelation of whey protein isolates (WPI): Effect of NaCl and protein concentration. Food Hydrocolloids 15 (2001), 233–237.
69. Ritger, P.L., Peppas, N.A., A simple equation for description of solute release II. Fickian and anomalous release from swellable devices. Journal of Controlled Release 5 (1987), 37–42.
70. Ruffin, E., Schmit, T., Lafitte, G., Dollat, J., Chambin, O., The impact of whey protein preheating on the properties of emulsion gel bead. Food Chemistry 151 (2014), 324–332.
71. Sala, G., de Wijk, R.A., van de Velde, F., van Aken, G.A., Matrix properties affect the sensory perception of emulsion-filled gels. Food Hydrocolloids 22 (2008), 353–363.
72. Sala, G., Van Aken, G.A., Stuart, M.A.C., Van De Velde, F., Effect of droplet-matrix interactions on large deformation properties of emulsion-filled gels. Journal of Texture Studies 38 (2007), 511–535.
73. Sala, G., van Vliet, T., Cohen Stuart, M.A., van de Velde, F., van Aken, G.A., Deformation and fracture of emulsion-filled gels: Effect of gelling agent concentration and oil droplet size. Food Hydrocolloids 23 (2009), 1853–1863.
74. Sarkar, A., Arfsten, J., Golay, P., Acquistapace, S., Heinrich, E., Microstructure and long-term stability of spray dried emulsions with ultra-high oil content. Food Hydrocolloids 52 (2016), 857–867.
75. Sarkar, A., Goh, K.K.T., Singh, R.P., Singh, H., Behaviour of an oil-in-water emulsion stabilized by β-lactoglobulin in an in vitro gastric model. Food Hydrocolloids 23 (2009), 1563–1569.
76. Sarkar, A., Juan, J.M., Kolodziejczyk, E., Acquistapace, S., Donato-Capel, L., Wooster, T.J., Impact of protein gel porosity on the digestion of lipid emulsions. Journal of Agricultural and Food Chemistry 63 (2015), 8829–8837.
77. Sarkar, A., Kamaruddin, H., Bentley, A., Wang, S., Emulsion stabilization by tomato seed protein isolate: Influence of pH, ionic strength and thermal treatment. Food Hydrocolloids 57 (2016), 160–168.
78. Sarkar, A., Murray, B.M., Holmes, M., Ettelaie, R., Abdalla, A., Yang, X., In vitro digestion of pickering emulsions stabilized by soft whey protein microgel particles: Influence of thermal treatment. Soft Matter 12 (2016), 3558–3569.
79. Sarkar, A., Singh, H., Emulsions and foams stabilised by milk proteins. McSweeney, P.L.H., O'Mahony, J.A., (eds.) Advanced dairy chemistry, 2016, Springer, New York, 133–153.
80. Satapathy, S., Singh, V.K., Sagiri, S.S., Agarwal, T., Banerjee, I., Bhattacharya, M.K., et al. Development and characterization of gelatin-based hydrogels, emulsion hydrogels, and bigels: A comparative study. Journal of Applied Polymer Science, 132, 2015.
81. Shewan, H.M., Stokes, J.R., Review of techniques to manufacture micro-hydrogel particles for the food industry and their applications. Journal of Food Engineering 119 (2013), 781–792.
82. Shogren, R.L., Viswanathan, A., Felker, F., Gross, R.A., Distribution of octenyl succinate groups in octenyl succinic anhydride modified waxy maize starch. Starch - Stärke 52 (2000), 196–204.
83. Singh, H., Sarkar, A., Behaviour of protein-stabilised emulsions under various physiological conditions. Advances in Colloid and Interface Science 165 (2011), 47–57.
84. Sok, L.V.L., Remondetto, G.E., Subirade, M., Cold gelation of β-lactoglobulin oil-in-water emulsions. Food Hydrocolloids 19 (2005), 269–278.
85. Sung, M.R., Xiao, H., Decker, E.A., McClements, D.J., Fabrication, characterization and properties of filled hydrogel particles formed by the emulsion-template method. Journal of Food Engineering 155 (2015), 16–21.
86. Sweedman, M.C., Tizzotti, M.J., Schäfer, C., Gilbert, R.G., Structure and physicochemical properties of octenyl succinic anhydride modified starches: A review. Carbohydrate Polymers 92 (2013), 905–920.
87. Tangsrianugul, N., Suphantharika, M., McClements, D.J., Simulated gastrointestinal fate of lipids encapsulated in starch hydrogels: Impact of normal and high amylose corn starch. Food Research International 78 (2015), 79–87.
88. Tesch, S., Gerhards, C., Schubert, H., Stabilization of emulsions by OSA starches. Journal of Food Engineering 54 (2002), 167–174.
89. Thirathumthavorn, D., Charoenrein, S., Thermal and pasting properties of native and acid-treated starches derivatized by 1-octenyl succinic anhydride. Carbohydrate Polymers 66 (2006), 258–265.
90. Thorne, J.B., Vine, G.J., Snowden, M.J., Microgel applications and commercial considerations. Colloid and Polymer Science 289 (2011), 625–646.
91. Velikov, K.P., Pelan, E., Colloidal delivery systems for micronutrients and nutraceuticals. Soft Matter 4 (2008), 1964–1980.
92. van Vliet, T., Rheological properties of filled gels. Influence of filler matrix interaction. Colloid and Polymer Science 266 (1988), 518–524.
93. Wang, X.Y., Li, X.X., Chen, L., Xie, F.W., Yu, L., Li, B., Preparation and characterisation of octenyl succinate starch as a delivery carrier for bioactive food components. Food Chemistry 126 (2011), 1218–1225.
94. Wei, J., Li, Y., Ngai, T., Tailor-made microgel particles: Synthesis and characterization. Colloids and Surfaces A: Physicochemical and Engineering Aspects 489 (2016), 122–127.
95. Wijayanti, H.B., Bansal, N., Deeth, H.C., Stability of whey proteins during thermal processing: A review. Comprehensive Reviews in Food Science and Food Safety 13 (2014), 1235–1251.
96. Wolz, M., Kulozik, U., Thermal denaturation kinetics of whey proteins at high protein concentrations. International Dairy Journal 49 (2015), 95–101.
97. Yost, R.A., Kinsella, J.E., Microstructure of whey-protein isolate gels containing emulsified butterfat droplets. Journal of Food Science 57 (1992), 892–897.
98. Zhang, Z., Zhang, R., Chen, L., Tong, Q., McClements, D.J., Designing hydrogel particles for controlled or targeted release of lipophilic bioactive agents in the gastrointestinal tract. European Polymer Journal 72 (2015), 698–716.
99. Zhang, Z., Zhang, R., Decker, E.A., McClements, D.J., Development of food-grade filled hydrogels for oral delivery of lipophilic active ingredients: pH-triggered release. Food Hydrocolloids 44 (2015), 345–352.
100. Zhang, Z., Zhang, R., Tong, Q., Decker, E.A., McClements, D.J., Food-grade filled hydrogels for oral delivery of lipophilic active ingredients: Temperature-triggered release microgels. Food Research International 69 (2015), 274–280.