Cross-linked starch microspheres: Effect of cross-linking condition on the microsphere characteristics

Archives of Pharmacal Research

Volumn 29, Issue 12, 2006, Pages 1179-1186

  Atyabi, Fatemeh ^a,b   Manoochehri, Saeed ^a   Moghadam, Shadi H ^a,b   Dinarvand, Rassoul ^a,b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cross linking; Enzymatic degradation; Microspheres; Starch

Indexed keywords

EID: 33846017646     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02969311     Document Type: Article

References (21)

1. Atyabi, F., Inanloo, K., and Dinarvand, R., Bovine serum albumin-loaded pectinate beads as colonic peptide delivery system: Preparation and in vitro characterization. Drug Deliv., 12, 367-375 (2005a).
2. Atyabi, F., Majzoob, S., Iman, M., Salehi, M., and Dorkoosh, F., In vitro evaluation and modification of pectinate gel beads containing trimethyl chitosan, as a multi-particulate system for delivery of water-soluble macromolecules to colon. Carbohydr. Polym., 61, 39-51 (2005b).
3. Azevedo, H. S., Gama, F. M., and Reis, R. L., In vitro assessment of the enzymatic degradation of several starch based biomaterials. Biomacromolecules, 4, 1703-1712 (2003).
4. Brena, B. M., Pazos, C., Franco-Fraguas, L., and Batista-Viera, F., Chromatographic methods for amylases. J. Chromatogr. B. Biomed. Appl., 684, 217-237 (1996).
5. Chawla, V., Tiwary, A. K., and Gupta, S., Characterization of polyvinylalcohol microspheres of diclofenac sodium: Application of statistical design. Drug Dev. Ind. Pharm., 26, 675-680 (2000).
6. Dumoulin, Y., Carriere, F., and Ingenito, A., Manufacture of cross-linked amylose useful as a excipient for control release of active compounds. U.S. Patents, US5807575 (1998).
7. Hamdi, G. and Ponchel, G., Enzymatic degradation of epichlorohydrin crosslinked starch microspheres by α-amylase. Pharmaceutical Research, 16, 867-875 (1999).
8. Hamdi, G., Ponchel, G., and Duche?Ne, D., An original method for studying in vitro the enzymatic degradation of cross-linked starch microspheres. J. Control. Release, 55, 193-201 (1998).
9. Hamdi, G., Ponchel, G., and Duchene, D., Formulation of epichlorohydrin cross-linked starch microspheres. J. Microencapsul., 18, 373-383 (2001).
10. Kost, J. and Shefer, S., Chemically-modified polysaccharides for enzymatically-controlled oral drug delivery. Biomaterials, 11, 695-698 (1990).
11. Lee, S. J., and Rosenberg, M., Preparation and properties of glutaraldehyde cross-linked whey protein-based microcapsules containing theophylline. J. Control. Release, 61, 123-136 (1999).
12. Lenaerts, V., Chouinard, F., Mateescu, M. A., and Ispas-Szabo, P., Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds. U.S. Patents, US6284273 (2001).
13. Lenaerts, V., Moussa, I., Dumoulin, Y., Mebsout, F., Chouinard, F., Szabo, P., Mateescu, M. A., Cartilier, L., and Marchessault, R., Cross-linked high amylose starch for controlled release of drugs: Recent advances. J. Control. Release, 53, 225-234 (1998).
14. Mulhbacher, J., Ispas-Szabo, P., Lenaerts, V., and Mateescu, M. A., Cross-linked high amylose starch derivatives as matrices for controlled release of high drug loadings. J. Control. Release, 76, 51-58 (2001).
15. Mulhbacher, J., Ispas-Szabo, P., and Mateescu, M. A., Cross-linked high amylose starch derivatives for drug release: II. Swelling properties and mechanistic study. Int. J. Pharm., 278, 231-238 (2004).
16. Mulhbacher, J. and Mateescu, M. A., Cross-linked high amylose starch derivatives for drug release: III. Diffusion properties. Int. J. Pharm., 297, 22-29 (2005).
17. Rahmouni, M., Chouinard, F., Nekka, F., Lenaerts, V., and Leroux, J. C., Enzymatic degradation of cross-linked high amylose starch tablets and its effect on in vitro release of sodium diclofenac. Eur. J. Pharm. Biopharm., 51, 191-198 (2001).
18. Rahmouni, M., Lenaerts, V., Massuelle, D., Doelker, E., Johnson, M., and Leroux, J. C., Characterization of Binary Mixtures Consisting of Cross-Linked High Amylose Starch and Hydroxypropylmethylcellulose Used in the Preparation of Controlled Release Tablets. Pharm. Dev. Technol., 8, 335-348 (2003).
19. Soppirnath, K. S. and Aminabhavi, T. M., Water transport and drug release study from cross-linked polyacrylamide grafted guar gum hydrogel microspheres for the controlled release application. Eur. J. Pharm. Biopharm., 53, 87-98 (2002).
20. Vincent, L., Chouinard, F., Mateescu, M. A., and Ispas-Szabo, P., Cross-linked high amylose starch having functional groups as a matrix for the slow release of pharmaceutical agents. European Patents, EP1059915 (2000).
21. Watts, P., Colonic drug delivery composition. U.S. Patents, US6228396 (2001).