-
1
-
-
77952577744
-
Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies
-
Alanio, C., Lemaitre, F., Law, H. K., Hasan, M. and Albert, M. L., Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies. Blood 2010. 115: 3718–3725.
-
(2010)
Blood
, vol.115
, pp. 3718-3725
-
-
Alanio, C.1
Lemaitre, F.2
Law, H.K.3
Hasan, M.4
Albert, M.L.5
-
2
-
-
18744382407
-
Cytolytic T-cell responses of cancer patients vaccinated with a MAGE antigen
-
Coulie, P. G., Karanikas, V., Lurquin, C., Colau, D., Connerotte, T., Hanagiri, T., Van Pel, A. et al., Cytolytic T-cell responses of cancer patients vaccinated with a MAGE antigen. Immunol. Rev. 2002. 188: 33–42.
-
(2002)
Immunol. Rev.
, vol.188
, pp. 33-42
-
-
Coulie, P.G.1
Karanikas, V.2
Lurquin, C.3
Colau, D.4
Connerotte, T.5
Hanagiri, T.6
Van Pel, A.7
-
3
-
-
33646179699
-
Human T cell responses against melanoma
-
Boon, T., Coulie, P. G., Van den Eynde, B. J. and van der Bruggen, P., Human T cell responses against melanoma. Annu. Rev. Immunol. 2006. 24: 175–208.
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 175-208
-
-
Boon, T.1
Coulie, P.G.2
Van den Eynde, B.J.3
van der Bruggen, P.4
-
4
-
-
0033862362
-
High frequencies of circulating melanoma-reactive CD8+ T cells in patients with advanced melanoma
-
Letsch, A., Keilholz, U., Schadendorf, D., Nagorsen, D., Schmittel, A., Thiel, E. and Scheibenbogen, C., High frequencies of circulating melanoma-reactive CD8+ T cells in patients with advanced melanoma. Int. J. Cancer 2000. 87: 659–664.
-
(2000)
Int. J. Cancer
, vol.87
, pp. 659-664
-
-
Letsch, A.1
Keilholz, U.2
Schadendorf, D.3
Nagorsen, D.4
Schmittel, A.5
Thiel, E.6
Scheibenbogen, C.7
-
5
-
-
0037018098
-
Estimating the precursor frequency of naive antigen-specific CD8 T cells
-
Blattman, J. N., Antia, R., Sourdive, D. J., Wang, X., Kaech, S. M., Murali-Krishna, K., Altman, J. D. et al., Estimating the precursor frequency of naive antigen-specific CD8 T cells. J. Exp. Med. 2002. 195: 657–664.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 657-664
-
-
Blattman, J.N.1
Antia, R.2
Sourdive, D.J.3
Wang, X.4
Kaech, S.M.5
Murali-Krishna, K.6
Altman, J.D.7
-
6
-
-
44649127931
-
Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection
-
Obar, J. J., Khanna, K. M. and Lefrancois, L., Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection. Immunity 2008. 28: 859–869.
-
(2008)
Immunity
, vol.28
, pp. 859-869
-
-
Obar, J.J.1
Khanna, K.M.2
Lefrancois, L.3
-
7
-
-
49649116676
-
Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance
-
Kotturi, M. F., Scott, I., Wolfe, T., Peters, B., Sidney, J., Cheroutre, H., von Herrath, M. G. et al., Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance. J. Immunol. 2008. 181: 2124–2133.
-
(2008)
J. Immunol.
, vol.181
, pp. 2124-2133
-
-
Kotturi, M.F.1
Scott, I.2
Wolfe, T.3
Peters, B.4
Sidney, J.5
Cheroutre, H.6
von Herrath, M.G.7
-
8
-
-
0037124362
-
Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells
-
Goldrath, A. W., Sivakumar, P. V., Glaccum, M., Kennedy, M. K., Bevan, M. J., Benoist, C., Mathis, D. et al., Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells. J. Exp. Med. 2002. 195: 1515–1522.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1515-1522
-
-
Goldrath, A.W.1
Sivakumar, P.V.2
Glaccum, M.3
Kennedy, M.K.4
Bevan, M.J.5
Benoist, C.6
Mathis, D.7
-
9
-
-
34548027000
-
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor
-
Joshi, N. S., Cui, W., Chandele, A., Lee, H. K., Urso, D. R., Hagman, J., Gapin, L. et al., Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 2007. 27: 281–295.
-
(2007)
Immunity
, vol.27
, pp. 281-295
-
-
Joshi, N.S.1
Cui, W.2
Chandele, A.3
Lee, H.K.4
Urso, D.R.5
Hagman, J.6
Gapin, L.7
-
10
-
-
55749101748
-
IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response
-
Rubinstein, M. P., Lind, N. A., Purton, J. F., Filippou, P., Best, J. A., McGhee, P. A., Surh, C. D. et al., IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response. Blood 2008. 112: 3704–3712.
-
(2008)
Blood
, vol.112
, pp. 3704-3712
-
-
Rubinstein, M.P.1
Lind, N.A.2
Purton, J.F.3
Filippou, P.4
Best, J.A.5
McGhee, P.A.6
Surh, C.D.7
-
11
-
-
0037074012
-
Molecular and functional profiling of memory CD8 T cell differentiation
-
Kaech, S. M., Hemby, S., Kersh, E. and Ahmed, R., Molecular and functional profiling of memory CD8 T cell differentiation. Cell 2002. 111: 837–851.
-
(2002)
Cell
, vol.111
, pp. 837-851
-
-
Kaech, S.M.1
Hemby, S.2
Kersh, E.3
Ahmed, R.4
-
12
-
-
0347382593
-
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
-
Kaech, S. M., Tan, J. T., Wherry, E. J., Konieczny, B. T., Surh, C. D. and Ahmed, R., Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat. Immunol. 2003. 4: 1191–1198.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1191-1198
-
-
Kaech, S.M.1
Tan, J.T.2
Wherry, E.J.3
Konieczny, B.T.4
Surh, C.D.5
Ahmed, R.6
-
13
-
-
74549162832
-
Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo
-
Kalia, V., Sarkar, S., Subramaniam, S., Haining, W. N., Smith, K. A. and Ahmed, R., Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. Immunity 2010. 32: 91–103.
-
(2010)
Immunity
, vol.32
, pp. 91-103
-
-
Kalia, V.1
Sarkar, S.2
Subramaniam, S.3
Haining, W.N.4
Smith, K.A.5
Ahmed, R.6
-
14
-
-
41149099559
-
Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
-
Sarkar, S., Kalia, V., Haining, W. N., Konieczny, B. T., Subramaniam, S. and Ahmed, R., Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. J. Exp. Med. 2008. 205: 625–640.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 625-640
-
-
Sarkar, S.1
Kalia, V.2
Haining, W.N.3
Konieczny, B.T.4
Subramaniam, S.5
Ahmed, R.6
-
15
-
-
84882603974
-
Environmental cues dictate the fate of individual CD8+ T cells responding to infection
-
Plumlee, C. R., Sheridan, B. S., Cicek, B. B. and Lefrancois, L., Environmental cues dictate the fate of individual CD8+ T cells responding to infection. Immunity 2013. 39: 347–356.
-
(2013)
Immunity
, vol.39
, pp. 347-356
-
-
Plumlee, C.R.1
Sheridan, B.S.2
Cicek, B.B.3
Lefrancois, L.4
-
16
-
-
77953520973
-
One naive T cell, multiple fates in CD8+ T cell differentiation
-
Gerlach, C., van Heijst, J. W., Swart, E., Sie, D., Armstrong, N., Kerkhoven, R. M., Zehn, D. et al., One naive T cell, multiple fates in CD8+ T cell differentiation. J. Exp. Med. 2010. 207: 1235–1246.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1235-1246
-
-
Gerlach, C.1
van Heijst, J.W.2
Swart, E.3
Sie, D.4
Armstrong, N.5
Kerkhoven, R.M.6
Zehn, D.7
-
17
-
-
84877601429
-
Heterogeneous differentiation patterns of individual CD8+ T cells
-
Gerlach, C., Rohr, J. C., Perie, L., van Rooij, N., van Heijst, J. W., Velds, A., Urbanus, J. et al., Heterogeneous differentiation patterns of individual CD8+ T cells. Science 2013. 340: 635–639.
-
(2013)
Science
, vol.340
, pp. 635-639
-
-
Gerlach, C.1
Rohr, J.C.2
Perie, L.3
van Rooij, N.4
van Heijst, J.W.5
Velds, A.6
Urbanus, J.7
-
18
-
-
53349143662
-
Dissecting T cell lineage relationships by cellular barcoding
-
Schepers, K., Swart, E., van Heijst, J. W., Gerlach, C., Castrucci, M., Sie, D., Heimerikx, M. et al., Dissecting T cell lineage relationships by cellular barcoding. J. Exp. Med. 2008. 205: 2309–2318.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2309-2318
-
-
Schepers, K.1
Swart, E.2
van Heijst, J.W.3
Gerlach, C.4
Castrucci, M.5
Sie, D.6
Heimerikx, M.7
-
19
-
-
84904394259
-
Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells
-
Graef, P., Buchholz, V. R., Stemberger, C., Flossdorf, M., Henkel, L., Schiemann, M., Drexler, I. et al., Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells. Immunity 2014. 41: 116–126.
-
(2014)
Immunity
, vol.41
, pp. 116-126
-
-
Graef, P.1
Buchholz, V.R.2
Stemberger, C.3
Flossdorf, M.4
Henkel, L.5
Schiemann, M.6
Drexler, I.7
-
20
-
-
0033554726
-
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
-
Sallusto, F., Lenig, D., Forster, R., Lipp, M. and Lanzavecchia, A., Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999. 401: 708–712.
-
(1999)
Nature
, vol.401
, pp. 708-712
-
-
Sallusto, F.1
Lenig, D.2
Forster, R.3
Lipp, M.4
Lanzavecchia, A.5
-
21
-
-
0035937587
-
Preferential localization of effector memory cells in nonlymphoid tissue
-
Masopust, D., Vezys, V., Marzo, A. L. and Lefrancois, L., Preferential localization of effector memory cells in nonlymphoid tissue. Science 2001. 291: 2413–2417.
-
(2001)
Science
, vol.291
, pp. 2413-2417
-
-
Masopust, D.1
Vezys, V.2
Marzo, A.L.3
Lefrancois, L.4
-
22
-
-
84866735170
-
Paths to stemness: building the ultimate antitumour T cell
-
Gattinoni, L., Klebanoff, C. A. and Restifo, N. P., Paths to stemness: building the ultimate antitumour T cell. Nat. Rev. Cancer 2012. 12: 671–684.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 671-684
-
-
Gattinoni, L.1
Klebanoff, C.A.2
Restifo, N.P.3
-
23
-
-
80053997259
-
A human memory T cell subset with stem cell-like properties
-
Gattinoni, L., Lugli, E., Ji, Y., Pos, Z., Paulos, C. M., Quigley, M. F., Almeida, J. R. et al., A human memory T cell subset with stem cell-like properties. Nat. Med. 2011. 17: 1290–1297.
-
(2011)
Nat. Med.
, vol.17
, pp. 1290-1297
-
-
Gattinoni, L.1
Lugli, E.2
Ji, Y.3
Pos, Z.4
Paulos, C.M.5
Quigley, M.F.6
Almeida, J.R.7
-
24
-
-
0038375013
-
Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines
-
Geginat, J., Lanzavecchia, A. and Sallusto, F., Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines. Blood 2003. 101: 4260–4266.
-
(2003)
Blood
, vol.101
, pp. 4260-4266
-
-
Geginat, J.1
Lanzavecchia, A.2
Sallusto, F.3
-
25
-
-
78149278086
-
Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence
-
Wakim, L. M., Woodward-Davis, A. and Bevan, M. J., Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence. Proc. Natl. Acad. Sci. USA 2010. 107: 17872–17879.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 17872-17879
-
-
Wakim, L.M.1
Woodward-Davis, A.2
Bevan, M.J.3
-
26
-
-
84899553624
-
Lung niches for the generation and maintenance of tissue-resident memory T cells
-
Turner, D. L., Bickham, K. L., Thome, J. J., Kim, C. Y., D'Ovidio, F., Wherry, E. J. and Farber, D. L., Lung niches for the generation and maintenance of tissue-resident memory T cells. Mucosal. Immunol. 2014. 7: 501–510.
-
(2014)
Mucosal. Immunol.
, vol.7
, pp. 501-510
-
-
Turner, D.L.1
Bickham, K.L.2
Thome, J.J.3
Kim, C.Y.4
D'Ovidio, F.5
Wherry, E.J.6
Farber, D.L.7
-
27
-
-
84869082967
-
A vaccine strategy that protects against genital herpes by establishing local memory T cells
-
Shin, H. and Iwasaki, A., A vaccine strategy that protects against genital herpes by establishing local memory T cells. Nature 2012. 491: 463–467.
-
(2012)
Nature
, vol.491
, pp. 463-467
-
-
Shin, H.1
Iwasaki, A.2
-
28
-
-
32044442312
-
Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population
-
Masopust, D., Vezys, V., Wherry, E. J., Barber, D. L. and Ahmed, R., Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population. J. Immunol. 2006. 176: 2079–2083.
-
(2006)
J. Immunol.
, vol.176
, pp. 2079-2083
-
-
Masopust, D.1
Vezys, V.2
Wherry, E.J.3
Barber, D.L.4
Ahmed, R.5
-
29
-
-
77949506152
-
Dynamic T cell migration program provides resident memory within intestinal epithelium
-
Masopust, D., Choo, D., Vezys, V., Wherry, E. J., Duraiswamy, J., Akondy, R., Wang, J. et al., Dynamic T cell migration program provides resident memory within intestinal epithelium. J. Exp. Med. 2010. 207: 553–564.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 553-564
-
-
Masopust, D.1
Choo, D.2
Vezys, V.3
Wherry, E.J.4
Duraiswamy, J.5
Akondy, R.6
Wang, J.7
-
30
-
-
84860788997
-
Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation
-
Mackay, L. K., Stock, A. T., Ma, J. Z., Jones, C. M., Kent, S. J., Mueller, S. N., Heath, W. R. et al., Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation. Proc. Natl. Acad. Sci. USA 2012. 109: 7037–7042.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 7037-7042
-
-
Mackay, L.K.1
Stock, A.T.2
Ma, J.Z.3
Jones, C.M.4
Kent, S.J.5
Mueller, S.N.6
Heath, W.R.7
-
31
-
-
84856072398
-
Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated CTCL patients
-
Clark, R. A., Watanabe, R., Teague, J. E., Schlapbach, C., Tawa, M. C., Adams, N., Dorosario, A. A. et al., Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated CTCL patients. Sci. Transl. Med. 2012. 4: 117ra117.
-
(2012)
Sci. Transl. Med.
, vol.4
, pp. 117ra117
-
-
Clark, R.A.1
Watanabe, R.2
Teague, J.E.3
Schlapbach, C.4
Tawa, M.C.5
Adams, N.6
Dorosario, A.A.7
-
32
-
-
84888008030
-
The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin
-
Mackay, L. K., Rahimpour, A., Ma, J. Z., Collins, N., Stock, A. T., Hafon, M. L., Vega-Ramos, J. et al., The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin. Nat. Immunol. 2013. 14: 1294–1301.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 1294-1301
-
-
Mackay, L.K.1
Rahimpour, A.2
Ma, J.Z.3
Collins, N.4
Stock, A.T.5
Hafon, M.L.6
Vega-Ramos, J.7
-
33
-
-
84885863119
-
Transforming growth factor-beta signaling controls the formation and maintenance of gut-resident memory T cells by regulating migration and retention
-
Zhang, N. and Bevan, M. J., Transforming growth factor-beta signaling controls the formation and maintenance of gut-resident memory T cells by regulating migration and retention. Immunity 2013. 39: 687–696.
-
(2013)
Immunity
, vol.39
, pp. 687-696
-
-
Zhang, N.1
Bevan, M.J.2
-
34
-
-
84861163967
-
Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues
-
Casey, K. A., Fraser, K. A., Schenkel, J. M., Moran, A., Abt, M. C., Beura, L. K., Lucas, P. J. et al., Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues. J. Immunol. 2012. 188: 4866–4875.
-
(2012)
J. Immunol.
, vol.188
, pp. 4866-4875
-
-
Casey, K.A.1
Fraser, K.A.2
Schenkel, J.M.3
Moran, A.4
Abt, M.C.5
Beura, L.K.6
Lucas, P.J.7
-
35
-
-
28644437672
-
Host-reactive CD8+ memory stem cells in graft-versus-host disease
-
Zhang, Y., Joe, G., Hexner, E., Zhu, J. and Emerson, S. G., Host-reactive CD8+ memory stem cells in graft-versus-host disease. Nat. Med. 2005. 11: 1299–1305.
-
(2005)
Nat. Med.
, vol.11
, pp. 1299-1305
-
-
Zhang, Y.1
Joe, G.2
Hexner, E.3
Zhu, J.4
Emerson, S.G.5
-
36
-
-
27144467425
-
Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets
-
Willinger, T., Freeman, T., Hasegawa, H., McMichael, A. J. and Callan, M. F., Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets. J. Immunol. 2005. 175: 5895–5903.
-
(2005)
J. Immunol.
, vol.175
, pp. 5895-5903
-
-
Willinger, T.1
Freeman, T.2
Hasegawa, H.3
McMichael, A.J.4
Callan, M.F.5
-
37
-
-
0036884742
-
Progressive differentiation and selection of the fittest in the immune response
-
Lanzavecchia, A. and Sallusto, F., Progressive differentiation and selection of the fittest in the immune response. Nat. Rev. Immunol. 2002. 2: 982–987.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 982-987
-
-
Lanzavecchia, A.1
Sallusto, F.2
-
38
-
-
33745083070
-
CD8+ T-cell memory in tumor immunology and immunotherapy
-
Klebanoff, C. A., Gattinoni, L. and Restifo, N. P., CD8+ T-cell memory in tumor immunology and immunotherapy. Immunol. Rev. 2006. 211: 214–224.
-
(2006)
Immunol. Rev.
, vol.211
, pp. 214-224
-
-
Klebanoff, C.A.1
Gattinoni, L.2
Restifo, N.P.3
-
39
-
-
84898019055
-
Lineage relationship of effector and memory T cells
-
Restifo, N. P. and Gattinoni, L., Lineage relationship of effector and memory T cells. Curr. Opin. Immunol. 2013. 25: 556–563.
-
(2013)
Curr. Opin. Immunol.
, vol.25
, pp. 556-563
-
-
Restifo, N.P.1
Gattinoni, L.2
-
40
-
-
84875448616
-
Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation
-
Best, J. A., Blair, D. A., Knell, J., Yang, E., Mayya, V., Doedens, A., Dustin, M. L. et al., Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation. Nat. Immunol. 2013. 14: 404–412.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 404-412
-
-
Best, J.A.1
Blair, D.A.2
Knell, J.3
Yang, E.4
Mayya, V.5
Doedens, A.6
Dustin, M.L.7
-
41
-
-
84924301515
-
Initial viral load determines the magnitude of the human CD8 T cell response to yellow fever vaccination
-
Akondy, R. S., Johnson, P. L., Nakaya, H. I., Edupuganti, S., Mulligan, M. J., Lawson, B., Miller, J. D., Pulendran, B., Antia, R. and Ahmed, R. Initial viral load determines the magnitude of the human CD8 T cell response to yellow fever vaccination. Proc Natl Acad Sci U S A 2015. 112: 3050–3055.
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 3050-3055
-
-
Akondy, R.S.1
Johnson, P.L.2
Nakaya, H.I.3
Edupuganti, S.4
Mulligan, M.J.5
Lawson, B.6
Miller, J.D.7
Pulendran, B.8
Antia, R.9
Ahmed, R.10
-
42
-
-
77952313777
-
Differentiation of effector CD4 T cell populations (*)
-
Zhu, J., Yamane, H. and Paul, W. E., Differentiation of effector CD4 T cell populations (*). Annu. Rev. Immunol. 2010. 28: 445–489.
-
(2010)
Annu. Rev. Immunol.
, vol.28
, pp. 445-489
-
-
Zhu, J.1
Yamane, H.2
Paul, W.E.3
-
43
-
-
78650947473
-
Interplay of transcription factors in T-cell differentiation and function: the role of Runx
-
Wong, W. F., Kohu, K., Chiba, T., Sato, T. and Satake, M., Interplay of transcription factors in T-cell differentiation and function: the role of Runx. Immunology 2011. 132: 157–164.
-
(2011)
Immunology
, vol.132
, pp. 157-164
-
-
Wong, W.F.1
Kohu, K.2
Chiba, T.3
Sato, T.4
Satake, M.5
-
44
-
-
80055109080
-
Transcriptional control of T-cell development
-
Naito, T., Tanaka, H., Naoe, Y. and Taniuchi, I., Transcriptional control of T-cell development. Int. Immunol. 2011. 23: 661–668.
-
(2011)
Int. Immunol.
, vol.23
, pp. 661-668
-
-
Naito, T.1
Tanaka, H.2
Naoe, Y.3
Taniuchi, I.4
-
45
-
-
84911201387
-
Molecular regulation of effector and memory T cell differentiation
-
Chang, J. T., Wherry, E. J. and Goldrath, A. W., Molecular regulation of effector and memory T cell differentiation. Nat. Immunol. 2014. 15: 1104–1115.
-
(2014)
Nat. Immunol.
, vol.15
, pp. 1104-1115
-
-
Chang, J.T.1
Wherry, E.J.2
Goldrath, A.W.3
-
46
-
-
84867896903
-
Transcriptional control of effector and memory CD8+ T cell differentiation
-
Kaech, S. M. and Cui, W., Transcriptional control of effector and memory CD8+ T cell differentiation. Nat. Rev. Immunol. 2012. 12: 749–761.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 749-761
-
-
Kaech, S.M.1
Cui, W.2
-
47
-
-
33745345216
-
Unidirectional development of CD8+ central memory T cells into protective Listeria-specific effector memory T cells
-
Huster, K. M., Koffler, M., Stemberger, C., Schiemann, M., Wagner, H. and Busch, D. H., Unidirectional development of CD8+ central memory T cells into protective Listeria-specific effector memory T cells. Eur. J. Immunol. 2006. 36: 1453–1464.
-
(2006)
Eur. J. Immunol.
, vol.36
, pp. 1453-1464
-
-
Huster, K.M.1
Koffler, M.2
Stemberger, C.3
Schiemann, M.4
Wagner, H.5
Busch, D.H.6
-
48
-
-
23944461953
-
Initial T cell frequency dictates memory CD8+ T cell lineage commitment
-
Marzo, A. L., Klonowski, K. D., Le Bon, A., Borrow, P., Tough, D. F. and Lefrancois, L., Initial T cell frequency dictates memory CD8+ T cell lineage commitment. Nat. Immunol. 2005. 6: 793–799.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 793-799
-
-
Marzo, A.L.1
Klonowski, K.D.2
Le Bon, A.3
Borrow, P.4
Tough, D.F.5
Lefrancois, L.6
-
49
-
-
34250877389
-
Cutting edge: migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells
-
Marzo, A. L., Yagita, H. and Lefrancois, L., Cutting edge: migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells. J. Immunol. 2007. 179: 36–40.
-
(2007)
J. Immunol.
, vol.179
, pp. 36-40
-
-
Marzo, A.L.1
Yagita, H.2
Lefrancois, L.3
-
50
-
-
38449086421
-
Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation
-
Sarkar, S., Teichgraber, V., Kalia, V., Polley, A., Masopust, D., Harrington, L. E., Ahmed, R. et al., Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation. J. Immunol. 2007. 179: 6704–6714.
-
(2007)
J. Immunol.
, vol.179
, pp. 6704-6714
-
-
Sarkar, S.1
Teichgraber, V.2
Kalia, V.3
Polley, A.4
Masopust, D.5
Harrington, L.E.6
Ahmed, R.7
-
51
-
-
0037340417
-
Lineage relationship and protective immunity of memory CD8 T cell subsets
-
Wherry, E. J., Teichgraber, V., Becker, T. C., Masopust, D., Kaech, S. M., Antia, R., von Andrian, U. H. et al., Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat. Immunol. 2003. 4: 225–234.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 225-234
-
-
Wherry, E.J.1
Teichgraber, V.2
Becker, T.C.3
Masopust, D.4
Kaech, S.M.5
Antia, R.6
von Andrian, U.H.7
-
52
-
-
77957883572
-
Gene regulation by nucleosome positioning
-
Bai, L. and Morozov, A. V., Gene regulation by nucleosome positioning. Trends Genet. 2010. 26: 476–483.
-
(2010)
Trends Genet.
, vol.26
, pp. 476-483
-
-
Bai, L.1
Morozov, A.V.2
-
53
-
-
79959557189
-
Determinants of nucleosome organization in primary human cells
-
Valouev, A., Johnson, S. M., Boyd, S. D., Smith, C. L., Fire, A. Z. and Sidow, A., Determinants of nucleosome organization in primary human cells. Nature 2011. 474: 516–520.
-
(2011)
Nature
, vol.474
, pp. 516-520
-
-
Valouev, A.1
Johnson, S.M.2
Boyd, S.D.3
Smith, C.L.4
Fire, A.Z.5
Sidow, A.6
-
54
-
-
79960563344
-
Determinants and dynamics of genome accessibility
-
Bell, O., Tiwari, V. K., Thoma, N. H. and Schubeler, D., Determinants and dynamics of genome accessibility. Nat. Rev. Genet. 2011. 12: 554–564.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 554-564
-
-
Bell, O.1
Tiwari, V.K.2
Thoma, N.H.3
Schubeler, D.4
-
55
-
-
15744397041
-
Chromatin remodeling complexes: strength in diversity, precision through specialization
-
Cairns, B. R., Chromatin remodeling complexes: strength in diversity, precision through specialization. Curr. Opin. Genet. Dev. 2005. 15: 185–190.
-
(2005)
Curr. Opin. Genet. Dev.
, vol.15
, pp. 185-190
-
-
Cairns, B.R.1
-
56
-
-
0037062922
-
Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes
-
Chi, T. H., Wan, M., Zhao, K., Taniuchi, I., Chen, L., Littman, D. R. and Crabtree, G. R., Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes. Nature 2002. 418: 195–199.
-
(2002)
Nature
, vol.418
, pp. 195-199
-
-
Chi, T.H.1
Wan, M.2
Zhao, K.3
Taniuchi, I.4
Chen, L.5
Littman, D.R.6
Crabtree, G.R.7
-
57
-
-
10244236502
-
A BAF-centred view of the immune system
-
Chi, T., A BAF-centred view of the immune system. Nat. Rev. Immunol. 2004. 4: 965–977.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 965-977
-
-
Chi, T.1
-
58
-
-
33847070442
-
The role of chromatin during transcription
-
Li, B., Carey, M. and Workman, J. L., The role of chromatin during transcription. Cell 2007. 128: 707–719.
-
(2007)
Cell
, vol.128
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
59
-
-
0037179716
-
Active genes are tri-methylated at K4 of histone H3
-
Santos-Rosa, H., Schneider, R., Bannister, A. J., Sherriff, J., Bernstein, B. E., Emre, N. C. T., Schreiber, S. L. et al., Active genes are tri-methylated at K4 of histone H3. Nature 2002. 419: 407–411.
-
(2002)
Nature
, vol.419
, pp. 407-411
-
-
Santos-Rosa, H.1
Schneider, R.2
Bannister, A.J.3
Sherriff, J.4
Bernstein, B.E.5
Emre, N.C.T.6
Schreiber, S.L.7
-
60
-
-
79952534189
-
Regulation of chromatin by histone modifications
-
Bannister, A. J. and Kouzarides, T., Regulation of chromatin by histone modifications. Cell. Res. 2011. 21: 381–395.
-
(2011)
Cell. Res.
, vol.21
, pp. 381-395
-
-
Bannister, A.J.1
Kouzarides, T.2
-
61
-
-
46249112085
-
Combinatorial patterns of histone acetylations and methylations in the human genome
-
Wang, Z., Zang, C., Rosenfeld, J. A., Schones, D. E., Barski, A., Cuddapah, S., Cui, K. et al., Combinatorial patterns of histone acetylations and methylations in the human genome. Nat. Genet. 2008. 40: 897–903.
-
(2008)
Nat. Genet.
, vol.40
, pp. 897-903
-
-
Wang, Z.1
Zang, C.2
Rosenfeld, J.A.3
Schones, D.E.4
Barski, A.5
Cuddapah, S.6
Cui, K.7
-
62
-
-
0036211013
-
Histone acetylation: a switch between repressive and permissive chromatin. Second in review series on chromatin dynamics
-
Eberharter, A. and Becker, P. B., Histone acetylation: a switch between repressive and permissive chromatin. Second in review series on chromatin dynamics. EMBO Rep. 2002. 3: 224–229.
-
(2002)
EMBO Rep.
, vol.3
, pp. 224-229
-
-
Eberharter, A.1
Becker, P.B.2
-
63
-
-
0032030770
-
Histone acetylation and transcriptional regulatory mechanisms
-
Struhl, K., Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 1998. 12: 599–606.
-
(1998)
Genes Dev.
, vol.12
, pp. 599-606
-
-
Struhl, K.1
-
64
-
-
33845198169
-
Histone acetylation in gene regulation
-
Verdone, L., Agricola, E., Caserta, M. and Di Mauro, E., Histone acetylation in gene regulation. Brief. Funct. Genomic. Proteomic 2006. 5: 209–221.
-
(2006)
Brief. Funct. Genomic. Proteomic
, vol.5
, pp. 209-221
-
-
Verdone, L.1
Agricola, E.2
Caserta, M.3
Di Mauro, E.4
-
65
-
-
84863986133
-
Functions of DNA methylation: islands, start sites, gene bodies and beyond
-
Jones, P. A., Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat. Rev. Genet. 2012. 13: 484–492.
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 484-492
-
-
Jones, P.A.1
-
66
-
-
84878260646
-
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
-
Pastor, W. A., Aravind, L. and Rao, A., TETonic shift: biological roles of TET proteins in DNA demethylation and transcription. Nat. Rev. Mol. Cell Biol. 2013. 14: 341–356.
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 341-356
-
-
Pastor, W.A.1
Aravind, L.2
Rao, A.3
-
67
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani, M., Koh, K. P., Shen, Y., Pastor, W. A., Bandukwala, H., Brudno, Y., Agarwal, S. et al., Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 2009. 324: 930–935.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
-
68
-
-
84957922469
-
Dynamics of epigenetic regulation at the single-cell level
-
Bintu, L., Yong, J., Antebi, Y. E., McCue, K., Kazuki, Y., Uno, N., Oshimura, M. et al., Dynamics of epigenetic regulation at the single-cell level. Science 2016. 351: 720–724.
-
(2016)
Science
, vol.351
, pp. 720-724
-
-
Bintu, L.1
Yong, J.2
Antebi, Y.E.3
McCue, K.4
Kazuki, Y.5
Uno, N.6
Oshimura, M.7
-
69
-
-
0037087576
-
Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors
-
Katan-Khaykovich, Y. and Struhl, K., Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors. Genes Dev. 2002. 16: 743–752.
-
(2002)
Genes Dev.
, vol.16
, pp. 743-752
-
-
Katan-Khaykovich, Y.1
Struhl, K.2
-
70
-
-
84888994574
-
Cross-talk between site-specific transcription factors and DNA methylation states
-
Blattler, A. and Farnham, P. J., Cross-talk between site-specific transcription factors and DNA methylation states. J. Biol. Chem. 2013. 288: 34287–34294.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 34287-34294
-
-
Blattler, A.1
Farnham, P.J.2
-
71
-
-
33745811234
-
The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells
-
Li, H., Rauch, T., Chen, Z. X., Szabo, P. E., Riggs, A. D. and Pfeifer, G. P., The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells. J. Biol. Chem. 2006. 281: 19489–19500.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 19489-19500
-
-
Li, H.1
Rauch, T.2
Chen, Z.X.3
Szabo, P.E.4
Riggs, A.D.5
Pfeifer, G.P.6
-
72
-
-
84925546982
-
Epigenetic control of myeloid cell differentiation, identity and function
-
Alvarez-Errico, D., Vento-Tormo, R., Sieweke, M. and Ballestar, E., Epigenetic control of myeloid cell differentiation, identity and function. Nat. Rev. Immunol. 2015. 15: 7–17.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 7-17
-
-
Alvarez-Errico, D.1
Vento-Tormo, R.2
Sieweke, M.3
Ballestar, E.4
-
73
-
-
78049414227
-
Epigenetic reprogramming in plant and animal development
-
Feng, S., Jacobsen, S. E. and Reik, W., Epigenetic reprogramming in plant and animal development. Science 2010. 330: 622–627.
-
(2010)
Science
, vol.330
, pp. 622-627
-
-
Feng, S.1
Jacobsen, S.E.2
Reik, W.3
-
74
-
-
84874194072
-
DNA methylation: roles in mammalian development
-
Smith, Z. D. and Meissner, A., DNA methylation: roles in mammalian development. Nat. Rev. Genet. 2013. 14: 204–220.
-
(2013)
Nat. Rev. Genet.
, vol.14
, pp. 204-220
-
-
Smith, Z.D.1
Meissner, A.2
-
75
-
-
0037372003
-
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
-
Jaenisch, R. and Bird, A., Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 2003. 33 (Suppl): 245–254.
-
(2003)
Nat. Genet.
, vol.33
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
76
-
-
84862824246
-
Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol
-
Chen, Y. F., Tseng, C. Y., Wang, H. W., Kuo, H. C., Yang, V. W. and Lee, O. K., Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol. Hepatology 2012. 55: 1193–1203.
-
(2012)
Hepatology
, vol.55
, pp. 1193-1203
-
-
Chen, Y.F.1
Tseng, C.Y.2
Wang, H.W.3
Kuo, H.C.4
Yang, V.W.5
Lee, O.K.6
-
77
-
-
84355166561
-
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
-
Kriks, S., Shim, J. W., Piao, J., Ganat, Y. M., Wakeman, D. R., Xie, Z., Carrillo-Reid, L. et al., Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 2011. 480: 547–551.
-
(2011)
Nature
, vol.480
, pp. 547-551
-
-
Kriks, S.1
Shim, J.W.2
Piao, J.3
Ganat, Y.M.4
Wakeman, D.R.5
Xie, Z.6
Carrillo-Reid, L.7
-
78
-
-
84861937125
-
One-step derivation of cardiomyocytes and mesenchymal stem cells from human pluripotent stem cells
-
Wei, H., Tan, G., Manasi, Qiu, S., Kong, G., Yong, P., Koh, C. et al., One-step derivation of cardiomyocytes and mesenchymal stem cells from human pluripotent stem cells. Stem Cell Res. 2012. 9: 87–100.
-
(2012)
Stem Cell Res.
, vol.9
, pp. 87-100
-
-
Wei, H.1
Tan, G.2
Manasi3
Qiu, S.4
Kong, G.5
Yong, P.6
Koh, C.7
-
79
-
-
84878292277
-
Transcriptional and epigenetic dynamics during specification of human embryonic stem cells
-
Gifford, C. A., Ziller, M. J., Gu, H., Trapnell, C., Donaghey, J., Tsankov, A., Shalek, A. K. et al., Transcriptional and epigenetic dynamics during specification of human embryonic stem cells. Cell 2013. 153: 1149–1163.
-
(2013)
Cell
, vol.153
, pp. 1149-1163
-
-
Gifford, C.A.1
Ziller, M.J.2
Gu, H.3
Trapnell, C.4
Donaghey, J.5
Tsankov, A.6
Shalek, A.K.7
-
80
-
-
35348982301
-
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
-
Loh, Y. H., Zhang, W., Chen, X., George, J. and Ng, H. H., Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. Genes Dev. 2007. 21: 2545–2557.
-
(2007)
Genes Dev.
, vol.21
, pp. 2545-2557
-
-
Loh, Y.H.1
Zhang, W.2
Chen, X.3
George, J.4
Ng, H.H.5
-
81
-
-
33745865934
-
Chromatin in pluripotent embryonic stem cells and differentiation
-
Meshorer, E. and Misteli, T., Chromatin in pluripotent embryonic stem cells and differentiation. Nat. Rev. Mol. Cell Biol. 2006. 7: 540–546.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 540-546
-
-
Meshorer, E.1
Misteli, T.2
-
82
-
-
4944245398
-
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
-
Vaquero, A., Scher, M., Lee, D., Erdjument-Bromage, H., Tempst, P. and Reinberg, D., Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol. Cell 2004. 16: 93–105.
-
(2004)
Mol. Cell
, vol.16
, pp. 93-105
-
-
Vaquero, A.1
Scher, M.2
Lee, D.3
Erdjument-Bromage, H.4
Tempst, P.5
Reinberg, D.6
-
83
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein, B. E., Mikkelsen, T. S., Xie, X., Kamal, M., Huebert, D. J., Cuff, J., Fry, B. et al., A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 2006. 125: 315–326.
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
-
84
-
-
67349169780
-
Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells
-
Araki, Y., Wang, Z., Zang, C., Wood, W. H., 3rd, Schones, D., Cui, K., Roh, T. Y. et al., Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells. Immunity 2009. 30: 912–925.
-
(2009)
Immunity
, vol.30
, pp. 912-925
-
-
Araki, Y.1
Wang, Z.2
Zang, C.3
Wood, W.H.4
Schones, D.5
Cui, K.6
Roh, T.Y.7
-
85
-
-
17444409344
-
Epigenetic reprogramming in mammals
-
Morgan, H. D., Santos, F., Green, K., Dean, W. and Reik, W., Epigenetic reprogramming in mammals. Hum. Mol. Genet. 2005. 14 (Spec No 1): R47–R58.
-
(2005)
Hum. Mol. Genet.
, vol.14
, Issue.Spec No 1
, pp. R47-R58
-
-
Morgan, H.D.1
Santos, F.2
Green, K.3
Dean, W.4
Reik, W.5
-
86
-
-
0034176639
-
Active demethylation of the paternal genome in the mouse zygote
-
Oswald, J., Engemann, S., Lane, N., Mayer, W., Olek, A., Fundele, R., Dean, W. et al., Active demethylation of the paternal genome in the mouse zygote. Curr. Biol. 2000. 10: 475–478.
-
(2000)
Curr. Biol.
, vol.10
, pp. 475-478
-
-
Oswald, J.1
Engemann, S.2
Lane, N.3
Mayer, W.4
Olek, A.5
Fundele, R.6
Dean, W.7
-
87
-
-
0036145567
-
Dynamic reprogramming of DNA methylation in the early mouse embryo
-
Santos, F., Hendrich, B., Reik, W. and Dean, W., Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev. Biol. 2002. 241: 172–182.
-
(2002)
Dev. Biol.
, vol.241
, pp. 172-182
-
-
Santos, F.1
Hendrich, B.2
Reik, W.3
Dean, W.4
-
88
-
-
84978291409
-
The epigenetics of embryo development
-
O'Neill, C., The epigenetics of embryo development. Anim. Front. 2015. 5: 42–49.
-
(2015)
Anim. Front.
, vol.5
, pp. 42-49
-
-
O'Neill, C.1
-
89
-
-
84900300766
-
Programming and inheritance of parental DNA methylomes in mammals
-
Wang, L., Zhang, J., Duan, J., Gao, X., Zhu, W., Lu, X., Yang, L. et al., Programming and inheritance of parental DNA methylomes in mammals. Cell 2014. 157: 979–991.
-
(2014)
Cell
, vol.157
, pp. 979-991
-
-
Wang, L.1
Zhang, J.2
Duan, J.3
Gao, X.4
Zhu, W.5
Lu, X.6
Yang, L.7
-
90
-
-
58149088296
-
Dynamic transition of Dnmt3b expression in mouse pre- and early post-implantation embryos
-
Hirasawa, R. and Sasaki, H., Dynamic transition of Dnmt3b expression in mouse pre- and early post-implantation embryos. Gene Expr. Patterns 2009. 9: 27–30.
-
(2009)
Gene Expr. Patterns
, vol.9
, pp. 27-30
-
-
Hirasawa, R.1
Sasaki, H.2
-
91
-
-
0042132027
-
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
-
Chen, T., Ueda, Y., Dodge, J. E., Wang, Z. and Li, E., Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol. Cell Biol. 2003. 23: 5594–5605.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 5594-5605
-
-
Chen, T.1
Ueda, Y.2
Dodge, J.E.3
Wang, Z.4
Li, E.5
-
92
-
-
4744372577
-
Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells
-
Jackson, M., Krassowska, A., Gilbert, N., Chevassut, T., Forrester, L., Ansell, J. and Ramsahoye, B., Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol. Cell Biol. 2004. 24: 8862–8871.
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 8862-8871
-
-
Jackson, M.1
Krassowska, A.2
Gilbert, N.3
Chevassut, T.4
Forrester, L.5
Ansell, J.6
Ramsahoye, B.7
-
93
-
-
33847293264
-
Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
-
Chen, T., Hevi, S., Gay, F., Tsujimoto, N., He, T., Zhang, B., Ueda, Y. et al., Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells. Nat. Genet. 2007. 39: 391–396.
-
(2007)
Nat. Genet.
, vol.39
, pp. 391-396
-
-
Chen, T.1
Hevi, S.2
Gay, F.3
Tsujimoto, N.4
He, T.5
Zhang, B.6
Ueda, Y.7
-
94
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li, E., Bestor, T. H. and Jaenisch, R., Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992. 69: 915–926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
95
-
-
84857160311
-
Trophoblast-specific DNA methylation occurs after the segregation of the trophectoderm and inner cell mass in the mouse periimplantation embryo
-
Nakanishi, M. O., Hayakawa, K., Nakabayashi, K., Hata, K., Shiota, K. and Tanaka, S., Trophoblast-specific DNA methylation occurs after the segregation of the trophectoderm and inner cell mass in the mouse periimplantation embryo. Epigenetics 2012. 7: 173–182.
-
(2012)
Epigenetics
, vol.7
, pp. 173-182
-
-
Nakanishi, M.O.1
Hayakawa, K.2
Nakabayashi, K.3
Hata, K.4
Shiota, K.5
Tanaka, S.6
-
96
-
-
84921468426
-
Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation
-
Mayle, A., Yang, L., Rodriguez, B., Zhou, T., Chang, E., Curry, C. V., Challen, G. A. et al., Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation. Blood 2015. 125: 629–638.
-
(2015)
Blood
, vol.125
, pp. 629-638
-
-
Mayle, A.1
Yang, L.2
Rodriguez, B.3
Zhou, T.4
Chang, E.5
Curry, C.V.6
Challen, G.A.7
-
97
-
-
70349469788
-
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
-
Trowbridge, J. J., Snow, J. W., Kim, J. and Orkin, S. H., DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell 2009. 5: 442–449.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 442-449
-
-
Trowbridge, J.J.1
Snow, J.W.2
Kim, J.3
Orkin, S.H.4
-
98
-
-
70350654370
-
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
-
Broske, A. M., Vockentanz, L., Kharazi, S., Huska, M. R., Mancini, E., Scheller, M., Kuhl, C. et al., DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat. Genet. 2009. 41: 1207–1215.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1207-1215
-
-
Broske, A.M.1
Vockentanz, L.2
Kharazi, S.3
Huska, M.R.4
Mancini, E.5
Scheller, M.6
Kuhl, C.7
-
99
-
-
79960064353
-
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
Moran-Crusio, K., Reavie, L., Shih, A., Abdel-Wahab, O., Ndiaye-Lobry, D., Lobry, C., Figueroa, M. E. et al., Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 2011. 20: 11–24.
-
(2011)
Cancer Cell
, vol.20
, pp. 11-24
-
-
Moran-Crusio, K.1
Reavie, L.2
Shih, A.3
Abdel-Wahab, O.4
Ndiaye-Lobry, D.5
Lobry, C.6
Figueroa, M.E.7
-
100
-
-
79960062301
-
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
-
Quivoron, C., Couronne, L., Della Valle, V., Lopez, C. K., Plo, I., Wagner-Ballon, O., Do Cruzeiro, M. et al., TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 2011. 20: 25–38.
-
(2011)
Cancer Cell
, vol.20
, pp. 25-38
-
-
Quivoron, C.1
Couronne, L.2
Della Valle, V.3
Lopez, C.K.4
Plo, I.5
Wagner-Ballon, O.6
Do Cruzeiro, M.7
-
101
-
-
80052284526
-
Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
-
Ko, M., Bandukwala, H. S., An, J., Lamperti, E. D., Thompson, E. C., Hastie, R., Tsangaratou, A. et al., Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proc. Natl. Acad. Sci. USA 2011. 108: 14566–14571.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 14566-14571
-
-
Ko, M.1
Bandukwala, H.S.2
An, J.3
Lamperti, E.D.4
Thompson, E.C.5
Hastie, R.6
Tsangaratou, A.7
-
102
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
Figueroa, M. E., Abdel-Wahab, O., Lu, C., Ward, P. S., Patel, J., Shih, A., Li, Y. et al., Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 2010. 18: 553–567.
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
Ward, P.S.4
Patel, J.5
Shih, A.6
Li, Y.7
-
103
-
-
84897995314
-
An epigenetic profile of early T-cell development from multipotent progenitors to committed T-cell descendants
-
Vigano, M. A., Ivanek, R., Balwierz, P., Berninger, P., van Nimwegen, E., Karjalainen, K. and Rolink, A., An epigenetic profile of early T-cell development from multipotent progenitors to committed T-cell descendants. Eur. J. Immunol. 2014. 44: 1181–1193.
-
(2014)
Eur. J. Immunol.
, vol.44
, pp. 1181-1193
-
-
Vigano, M.A.1
Ivanek, R.2
Balwierz, P.3
Berninger, P.4
van Nimwegen, E.5
Karjalainen, K.6
Rolink, A.7
-
104
-
-
77953809032
-
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells
-
Hawkins, R. D., Hon, G. C., Lee, L. K., Ngo, Q., Lister, R., Pelizzola, M., Edsall, L. E. et al., Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell 2010. 6: 479–491.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 479-491
-
-
Hawkins, R.D.1
Hon, G.C.2
Lee, L.K.3
Ngo, Q.4
Lister, R.5
Pelizzola, M.6
Edsall, L.E.7
-
105
-
-
18244365863
-
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
-
Lee, P. P., Fitzpatrick, D. R., Beard, C., Jessup, H. K., Lehar, S., Makar, K. W., Perez-Melgosa, M. et al., A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 2001. 15: 763–774.
-
(2001)
Immunity
, vol.15
, pp. 763-774
-
-
Lee, P.P.1
Fitzpatrick, D.R.2
Beard, C.3
Jessup, H.K.4
Lehar, S.5
Makar, K.W.6
Perez-Melgosa, M.7
-
106
-
-
0032143821
-
Helper T cell differentiation is controlled by the cell cycle
-
Bird, J. J., Brown, D. R., Mullen, A. C., Moskowitz, N. H., Mahowald, M. A., Sider, J. R., Gajewski, T. F. et al., Helper T cell differentiation is controlled by the cell cycle. Immunity 1998. 9: 229–237.
-
(1998)
Immunity
, vol.9
, pp. 229-237
-
-
Bird, J.J.1
Brown, D.R.2
Mullen, A.C.3
Moskowitz, N.H.4
Mahowald, M.A.5
Sider, J.R.6
Gajewski, T.F.7
-
107
-
-
58849088509
-
T-bet dependent removal of Sin3A-histone deacetylase complexes at the Ifng locus drives Th1 differentiation
-
Chang, S., Collins, P. L. and Aune, T. M., T-bet dependent removal of Sin3A-histone deacetylase complexes at the Ifng locus drives Th1 differentiation. J. Immunol. 2008. 181: 8372–8381.
-
(2008)
J. Immunol.
, vol.181
, pp. 8372-8381
-
-
Chang, S.1
Collins, P.L.2
Aune, T.M.3
-
108
-
-
84870027825
-
STATs shape the active enhancer landscape of T cell populations
-
Vahedi, G., Takahashi, H., Nakayamada, S., Sun, H. W., Sartorelli, V., Kanno, Y. and O'Shea, J. J., STATs shape the active enhancer landscape of T cell populations. Cell 2012. 151: 981–993.
-
(2012)
Cell
, vol.151
, pp. 981-993
-
-
Vahedi, G.1
Takahashi, H.2
Nakayamada, S.3
Sun, H.W.4
Sartorelli, V.5
Kanno, Y.6
O'Shea, J.J.7
-
109
-
-
4644231710
-
DNA methylation is a nonredundant repressor of the Th2 effector program
-
Makar, K. W. and Wilson, C. B., DNA methylation is a nonredundant repressor of the Th2 effector program. J. Immunol. 2004. 173: 4402–4406.
-
(2004)
J. Immunol.
, vol.173
, pp. 4402-4406
-
-
Makar, K.W.1
Wilson, C.B.2
-
110
-
-
76749133610
-
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
-
Zheng, Y., Josefowicz, S., Chaudhry, A., Peng, X. P., Forbush, K. and Rudensky, A. Y., Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 2010. 463: 808–812.
-
(2010)
Nature
, vol.463
, pp. 808-812
-
-
Zheng, Y.1
Josefowicz, S.2
Chaudhry, A.3
Peng, X.P.4
Forbush, K.5
Rudensky, A.Y.6
-
111
-
-
33644854871
-
A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory
-
Murayama, A., Sakura, K., Nakama, M., Yasuzawa-Tanaka, K., Fujita, E., Tateishi, Y., Wang, Y. et al., A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory. EMBO J. 2006. 25: 1081–1092.
-
(2006)
EMBO J.
, vol.25
, pp. 1081-1092
-
-
Murayama, A.1
Sakura, K.2
Nakama, M.3
Yasuzawa-Tanaka, K.4
Fujita, E.5
Tateishi, Y.6
Wang, Y.7
-
112
-
-
33645770934
-
DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion
-
Chappell, C., Beard, C., Altman, J., Jaenisch, R. and Jacob, J., DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion. J. Immunol. 2006. 176: 4562–4572.
-
(2006)
J. Immunol.
, vol.176
, pp. 4562-4572
-
-
Chappell, C.1
Beard, C.2
Altman, J.3
Jaenisch, R.4
Jacob, J.5
-
113
-
-
84931301873
-
DNA methylation secures CD4(+) and CD8(+) T cell lineage borders
-
Feng, Y. and Rudensky, A. Y., DNA methylation secures CD4(+) and CD8(+) T cell lineage borders. Nat. Immunol. 2015. 16: 681–683.
-
(2015)
Nat. Immunol.
, vol.16
, pp. 681-683
-
-
Feng, Y.1
Rudensky, A.Y.2
-
114
-
-
84931327865
-
Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages
-
Sellars, M., Huh, J. R., Day, K., Issuree, P. D., Galan, C., Gobeil, S., Absher, D. et al., Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages. Nat. Immunol. 2015. 16: 746–754.
-
(2015)
Nat. Immunol.
, vol.16
, pp. 746-754
-
-
Sellars, M.1
Huh, J.R.2
Day, K.3
Issuree, P.D.4
Galan, C.5
Gobeil, S.6
Absher, D.7
-
115
-
-
65549100376
-
Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1
-
Josefowicz, S. Z., Wilson, C. B. and Rudensky, A. Y., Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1. J. Immunol. 2009. 182: 6648–6652.
-
(2009)
J. Immunol.
, vol.182
, pp. 6648-6652
-
-
Josefowicz, S.Z.1
Wilson, C.B.2
Rudensky, A.Y.3
-
116
-
-
80053086090
-
Differentiation-dependent functional and epigenetic landscapes for cytokine genes in virus-specific CD8+ T cells
-
Denton, A. E., Russ, B. E., Doherty, P. C., Rao, S. and Turner, S. J., Differentiation-dependent functional and epigenetic landscapes for cytokine genes in virus-specific CD8+ T cells. Proc. Natl. Acad. Sci. USA 2011. 108: 15306–15311.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 15306-15311
-
-
Denton, A.E.1
Russ, B.E.2
Doherty, P.C.3
Rao, S.4
Turner, S.J.5
-
117
-
-
73349112246
-
Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression
-
Juelich, T., Sutcliffe, E. L., Denton, A., He, Y., Doherty, P. C., Parish, C. R., Turner, S. J. et al., Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression. J. Immunol. 2009. 183: 7063–7072.
-
(2009)
J. Immunol.
, vol.183
, pp. 7063-7072
-
-
Juelich, T.1
Sutcliffe, E.L.2
Denton, A.3
He, Y.4
Doherty, P.C.5
Parish, C.R.6
Turner, S.J.7
-
118
-
-
79952756708
-
Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status
-
Zediak, V. P., Johnnidis, J. B., Wherry, E. J. and Berger, S. L., Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status. J. Immunol. 2011. 186: 2705–2709.
-
(2011)
J. Immunol.
, vol.186
, pp. 2705-2709
-
-
Zediak, V.P.1
Johnnidis, J.B.2
Wherry, E.J.3
Berger, S.L.4
-
119
-
-
33745861718
-
Epigenetic remodeling of the IL-2 and IFN-gamma loci in memory CD8 T cells is influenced by CD4 T cells
-
Northrop, J. K., Thomas, R. M., Wells, A. D. and Shen, H., Epigenetic remodeling of the IL-2 and IFN-gamma loci in memory CD8 T cells is influenced by CD4 T cells. J. Immunol. 2006. 177: 1062–1069.
-
(2006)
J. Immunol.
, vol.177
, pp. 1062-1069
-
-
Northrop, J.K.1
Thomas, R.M.2
Wells, A.D.3
Shen, H.4
-
120
-
-
49049110982
-
Cutting edge: chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells
-
Northrop, J. K., Wells, A. D. and Shen, H., Cutting edge: chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells. J. Immunol. 2008. 181: 865–868.
-
(2008)
J. Immunol.
, vol.181
, pp. 865-868
-
-
Northrop, J.K.1
Wells, A.D.2
Shen, H.3
-
121
-
-
50949127683
-
Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B)
-
Araki, Y., Fann, M., Wersto, R. and Weng, N. P., Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B). J. Immunol. 2008. 180: 8102–8108.
-
(2008)
J. Immunol.
, vol.180
, pp. 8102-8108
-
-
Araki, Y.1
Fann, M.2
Wersto, R.3
Weng, N.P.4
-
122
-
-
84912096136
-
Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8(+) T cell differentiation
-
Russ, B. E., Olshanksy, M., Smallwood, H. S., Li, J., Denton, A. E., Prier, J. E., Stock, A. T. et al., Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8(+) T cell differentiation. Immunity 2014. 41: 853–865.
-
(2014)
Immunity
, vol.41
, pp. 853-865
-
-
Russ, B.E.1
Olshanksy, M.2
Smallwood, H.S.3
Li, J.4
Denton, A.E.5
Prier, J.E.6
Stock, A.T.7
-
123
-
-
84977536611
-
Lineage relationship of CD8 T cell subsets is revealed by progressive changes in the epigenetic landscape
-
Crompton, J. G., Narayanan, M., Cuddapah, S., Roychoudhuri, R., Ji, Y., Yang, W., Patel, S. J. et al., Lineage relationship of CD8 T cell subsets is revealed by progressive changes in the epigenetic landscape. Cell Mol. Immunol. 2015.
-
(2015)
Cell Mol. Immunol.
-
-
Crompton, J.G.1
Narayanan, M.2
Cuddapah, S.3
Roychoudhuri, R.4
Ji, Y.5
Yang, W.6
Patel, S.J.7
-
124
-
-
84956825522
-
Dynamic regulation of permissive histone modifications and GATA3 binding underpin acquisition of granzyme A expression by virus-specific CD8(+) T cells
-
Nguyen, M. L., Hatton, L., Li, J., Olshansky, M., Kelso, A., Russ, B. E. and Turner, S. J., Dynamic regulation of permissive histone modifications and GATA3 binding underpin acquisition of granzyme A expression by virus-specific CD8(+) T cells. Eur. J. Immunol. 2016. 46: 307–318.
-
(2016)
Eur. J. Immunol.
, vol.46
, pp. 307-318
-
-
Nguyen, M.L.1
Hatton, L.2
Li, J.3
Olshansky, M.4
Kelso, A.5
Russ, B.E.6
Turner, S.J.7
-
125
-
-
84928019813
-
Memory CD8 T cell transcriptional plasticity
-
Youngblood, B., Hale, J. S. and Ahmed, R., Memory CD8 T cell transcriptional plasticity. F1000Prime Rep. 2015. 7: 38.
-
(2015)
F1000Prime Rep.
, vol.7
, pp. 38
-
-
Youngblood, B.1
Hale, J.S.2
Ahmed, R.3
-
126
-
-
84905984263
-
The interface between transcriptional and epigenetic control of effector and memory CD8(+) T-cell differentiation
-
Gray, S. M., Kaech, S. M. and Staron, M. M., The interface between transcriptional and epigenetic control of effector and memory CD8(+) T-cell differentiation. Immunol. Rev. 2014. 261: 157–168.
-
(2014)
Immunol. Rev.
, vol.261
, pp. 157-168
-
-
Gray, S.M.1
Kaech, S.M.2
Staron, M.M.3
-
127
-
-
33646058925
-
Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells
-
Kersh, E. N., Fitzpatrick, D. R., Murali-Krishna, K., Shires, J., Speck, S. H., Boss, J. M. and Ahmed, R., Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells. J. Immunol. 2006. 176: 4083–4093.
-
(2006)
J. Immunol.
, vol.176
, pp. 4083-4093
-
-
Kersh, E.N.1
Fitzpatrick, D.R.2
Murali-Krishna, K.3
Shires, J.4
Speck, S.H.5
Boss, J.M.6
Ahmed, R.7
-
128
-
-
84884256121
-
Global DNA methylation remodeling accompanies CD8 T cell effector function
-
Scharer, C. D., Barwick, B. G., Youngblood, B. A., Ahmed, R. and Boss, J. M., Global DNA methylation remodeling accompanies CD8 T cell effector function. J. Immunol. 2013. 191: 3419–3429.
-
(2013)
J. Immunol.
, vol.191
, pp. 3419-3429
-
-
Scharer, C.D.1
Barwick, B.G.2
Youngblood, B.A.3
Ahmed, R.4
Boss, J.M.5
-
129
-
-
84879211454
-
T-cell memory differentiation: insights from transcriptional signatures and epigenetics
-
Youngblood, B., Hale, J. S. and Ahmed, R., T-cell memory differentiation: insights from transcriptional signatures and epigenetics. Immunology 2013. 139: 277–284.
-
(2013)
Immunology
, vol.139
, pp. 277-284
-
-
Youngblood, B.1
Hale, J.S.2
Ahmed, R.3
-
130
-
-
0032416085
-
Viral immune evasion due to persistence of activated T cells without effector function
-
Zajac, A. J., Blattman, J. N., Murali-Krishna, K., Sourdive, D. J., Suresh, M., Altman, J. D. and Ahmed, R., Viral immune evasion due to persistence of activated T cells without effector function. J. Exp. Med. 1998. 188: 2205–2213.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2205-2213
-
-
Zajac, A.J.1
Blattman, J.N.2
Murali-Krishna, K.3
Sourdive, D.J.4
Suresh, M.5
Altman, J.D.6
Ahmed, R.7
-
131
-
-
0037383592
-
Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
-
Wherry, E. J., Blattman, J. N., Murali-Krishna, K., van der Most, R. and Ahmed, R., Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J. Virol. 2003. 77: 4911–4927.
-
(2003)
J. Virol.
, vol.77
, pp. 4911-4927
-
-
Wherry, E.J.1
Blattman, J.N.2
Murali-Krishna, K.3
van der Most, R.4
Ahmed, R.5
-
132
-
-
70349569569
-
Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
-
Ahmadzadeh, M., Johnson, L. A., Heemskerk, B., Wunderlich, J. R., Dudley, M. E., White, D. E. and Rosenberg, S. A., Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood 2009. 114: 1537–1544.
-
(2009)
Blood
, vol.114
, pp. 1537-1544
-
-
Ahmadzadeh, M.1
Johnson, L.A.2
Heemskerk, B.3
Wunderlich, J.R.4
Dudley, M.E.5
White, D.E.6
Rosenberg, S.A.7
-
133
-
-
70349562580
-
Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression
-
Mumprecht, S., Schurch, C., Schwaller, J., Solenthaler, M. and Ochsenbein, A. F., Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression. Blood 2009. 114: 1528–1536.
-
(2009)
Blood
, vol.114
, pp. 1528-1536
-
-
Mumprecht, S.1
Schurch, C.2
Schwaller, J.3
Solenthaler, M.4
Ochsenbein, A.F.5
-
134
-
-
84941745031
-
Magnitude and kinetics of CD8+ T cell activation during hyperacute HIV infection impact viral set point
-
Ndhlovu, Z. M., Kamya, P., Mewalal, N., Kloverpris, H. N., Nkosi, T., Pretorius, K., Laher, F. et al., Magnitude and kinetics of CD8+ T cell activation during hyperacute HIV infection impact viral set point. Immunity 2015. 43: 591–604.
-
(2015)
Immunity
, vol.43
, pp. 591-604
-
-
Ndhlovu, Z.M.1
Kamya, P.2
Mewalal, N.3
Kloverpris, H.N.4
Nkosi, T.5
Pretorius, K.6
Laher, F.7
-
135
-
-
84937837169
-
Molecular and cellular insights into T cell exhaustion
-
Wherry, E. J. and Kurachi, M., Molecular and cellular insights into T cell exhaustion. Nat. Rev. Immunol. 2015. 15: 486–499.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 486-499
-
-
Wherry, E.J.1
Kurachi, M.2
-
136
-
-
84926528302
-
Overcoming T cell exhaustion in infection and cancer
-
Pauken, K. E. and Wherry, E. J., Overcoming T cell exhaustion in infection and cancer. Trends Immunol. 2015. 36: 265–276.
-
(2015)
Trends Immunol.
, vol.36
, pp. 265-276
-
-
Pauken, K.E.1
Wherry, E.J.2
-
137
-
-
35349014587
-
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
-
Wherry, E. J., Ha, S. J., Kaech, S. M., Haining, W. N., Sarkar, S., Kalia, V., Subramaniam, S. et al., Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity 2007. 27: 670–684.
-
(2007)
Immunity
, vol.27
, pp. 670-684
-
-
Wherry, E.J.1
Ha, S.J.2
Kaech, S.M.3
Haining, W.N.4
Sarkar, S.5
Kalia, V.6
Subramaniam, S.7
-
138
-
-
84857059757
-
Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells
-
Youngblood, B., Wherry, E. J. and Ahmed, R., Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells. Curr. Opin. HIV AIDS 2012. 7: 50–57.
-
(2012)
Curr. Opin. HIV AIDS
, vol.7
, pp. 50-57
-
-
Youngblood, B.1
Wherry, E.J.2
Ahmed, R.3
-
139
-
-
84864378851
-
Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection
-
Angelosanto, J. M., Blackburn, S. D., Crawford, A. and Wherry, E. J., Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection. J. Virol. 2012. 86: 8161–8170.
-
(2012)
J. Virol.
, vol.86
, pp. 8161-8170
-
-
Angelosanto, J.M.1
Blackburn, S.D.2
Crawford, A.3
Wherry, E.J.4
-
140
-
-
84878229777
-
T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion
-
Utzschneider, D. T., Legat, A., Fuertes Marraco, S. A., Carrie, L., Luescher, I., Speiser, D. E. and Zehn, D., T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion. Nat. Immunol. 2013. 14: 603–610.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 603-610
-
-
Utzschneider, D.T.1
Legat, A.2
Fuertes Marraco, S.A.3
Carrie, L.4
Luescher, I.5
Speiser, D.E.6
Zehn, D.7
-
141
-
-
80053137239
-
Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells
-
Youngblood, B., Oestreich, K. J., Ha, S. J., Duraiswamy, J., Akondy, R. S., West, E. E., Wei, Z. et al., Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity 2011. 35: 400–412.
-
(2011)
Immunity
, vol.35
, pp. 400-412
-
-
Youngblood, B.1
Oestreich, K.J.2
Ha, S.J.3
Duraiswamy, J.4
Akondy, R.S.5
West, E.E.6
Wei, Z.7
-
142
-
-
84880119204
-
Cutting edge: prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells
-
Youngblood, B., Noto, A., Porichis, F., Akondy, R. S., Ndhlovu, Z. M., Austin, J. W., Bordi, R. et al., Cutting edge: prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells. J. Immunol. 2013. 191: 540–544.
-
(2013)
J. Immunol.
, vol.191
, pp. 540-544
-
-
Youngblood, B.1
Noto, A.2
Porichis, F.3
Akondy, R.S.4
Ndhlovu, Z.M.5
Austin, J.W.6
Bordi, R.7
-
143
-
-
84859403357
-
Inhibitory receptors on lymphocytes: insights from infections
-
Odorizzi, P. M. and Wherry, E. J., Inhibitory receptors on lymphocytes: insights from infections. J. Immunol. 2012. 188: 2957–2965.
-
(2012)
J. Immunol.
, vol.188
, pp. 2957-2965
-
-
Odorizzi, P.M.1
Wherry, E.J.2
-
144
-
-
77954956266
-
Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8(+) T cell differentiation
-
Wirth, T. C., Xue, H. H., Rai, D., Sabel, J. T., Bair, T., Harty, J. T. and Badovinac, V. P., Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8(+) T cell differentiation. Immunity 2010. 33: 128–140.
-
(2010)
Immunity
, vol.33
, pp. 128-140
-
-
Wirth, T.C.1
Xue, H.H.2
Rai, D.3
Sabel, J.T.4
Bair, T.5
Harty, J.T.6
Badovinac, V.P.7
-
145
-
-
33745810216
-
Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination
-
Masopust, D., Ha, S. J., Vezys, V. and Ahmed, R., Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination. J. Immunol. 2006. 177: 831–839.
-
(2006)
J. Immunol.
, vol.177
, pp. 831-839
-
-
Masopust, D.1
Ha, S.J.2
Vezys, V.3
Ahmed, R.4
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