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Volumn 46, Issue 7, 2016, Pages 1548-1562

Generating long-lived CD8+ T-cell memory: Insights from epigenetic programs

Author keywords

CD8+ T cell; DNA methylation; Epigenetics; Histone modification; Memory; T cell exhaustion

Indexed keywords

DNA; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; HISTONE; HISTONE ACETYLTRANSFERASE;

EID: 84978218294     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201545550     Document Type: Article
Times cited : (32)

References (145)
  • 1
    • 77952577744 scopus 로고    scopus 로고
    • Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies
    • Alanio, C., Lemaitre, F., Law, H. K., Hasan, M. and Albert, M. L., Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies. Blood 2010. 115: 3718–3725.
    • (2010) Blood , vol.115 , pp. 3718-3725
    • Alanio, C.1    Lemaitre, F.2    Law, H.K.3    Hasan, M.4    Albert, M.L.5
  • 6
    • 44649127931 scopus 로고    scopus 로고
    • Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection
    • Obar, J. J., Khanna, K. M. and Lefrancois, L., Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection. Immunity 2008. 28: 859–869.
    • (2008) Immunity , vol.28 , pp. 859-869
    • Obar, J.J.1    Khanna, K.M.2    Lefrancois, L.3
  • 7
    • 49649116676 scopus 로고    scopus 로고
    • Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance
    • Kotturi, M. F., Scott, I., Wolfe, T., Peters, B., Sidney, J., Cheroutre, H., von Herrath, M. G. et al., Naive precursor frequencies and MHC binding rather than the degree of epitope diversity shape CD8+ T cell immunodominance. J. Immunol. 2008. 181: 2124–2133.
    • (2008) J. Immunol. , vol.181 , pp. 2124-2133
    • Kotturi, M.F.1    Scott, I.2    Wolfe, T.3    Peters, B.4    Sidney, J.5    Cheroutre, H.6    von Herrath, M.G.7
  • 8
    • 0037124362 scopus 로고    scopus 로고
    • Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells
    • Goldrath, A. W., Sivakumar, P. V., Glaccum, M., Kennedy, M. K., Bevan, M. J., Benoist, C., Mathis, D. et al., Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells. J. Exp. Med. 2002. 195: 1515–1522.
    • (2002) J. Exp. Med. , vol.195 , pp. 1515-1522
    • Goldrath, A.W.1    Sivakumar, P.V.2    Glaccum, M.3    Kennedy, M.K.4    Bevan, M.J.5    Benoist, C.6    Mathis, D.7
  • 9
    • 34548027000 scopus 로고    scopus 로고
    • Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor
    • Joshi, N. S., Cui, W., Chandele, A., Lee, H. K., Urso, D. R., Hagman, J., Gapin, L. et al., Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 2007. 27: 281–295.
    • (2007) Immunity , vol.27 , pp. 281-295
    • Joshi, N.S.1    Cui, W.2    Chandele, A.3    Lee, H.K.4    Urso, D.R.5    Hagman, J.6    Gapin, L.7
  • 10
    • 55749101748 scopus 로고    scopus 로고
    • IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response
    • Rubinstein, M. P., Lind, N. A., Purton, J. F., Filippou, P., Best, J. A., McGhee, P. A., Surh, C. D. et al., IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response. Blood 2008. 112: 3704–3712.
    • (2008) Blood , vol.112 , pp. 3704-3712
    • Rubinstein, M.P.1    Lind, N.A.2    Purton, J.F.3    Filippou, P.4    Best, J.A.5    McGhee, P.A.6    Surh, C.D.7
  • 11
    • 0037074012 scopus 로고    scopus 로고
    • Molecular and functional profiling of memory CD8 T cell differentiation
    • Kaech, S. M., Hemby, S., Kersh, E. and Ahmed, R., Molecular and functional profiling of memory CD8 T cell differentiation. Cell 2002. 111: 837–851.
    • (2002) Cell , vol.111 , pp. 837-851
    • Kaech, S.M.1    Hemby, S.2    Kersh, E.3    Ahmed, R.4
  • 12
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech, S. M., Tan, J. T., Wherry, E. J., Konieczny, B. T., Surh, C. D. and Ahmed, R., Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat. Immunol. 2003. 4: 1191–1198.
    • (2003) Nat. Immunol. , vol.4 , pp. 1191-1198
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3    Konieczny, B.T.4    Surh, C.D.5    Ahmed, R.6
  • 13
    • 74549162832 scopus 로고    scopus 로고
    • Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo
    • Kalia, V., Sarkar, S., Subramaniam, S., Haining, W. N., Smith, K. A. and Ahmed, R., Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. Immunity 2010. 32: 91–103.
    • (2010) Immunity , vol.32 , pp. 91-103
    • Kalia, V.1    Sarkar, S.2    Subramaniam, S.3    Haining, W.N.4    Smith, K.A.5    Ahmed, R.6
  • 14
    • 41149099559 scopus 로고    scopus 로고
    • Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
    • Sarkar, S., Kalia, V., Haining, W. N., Konieczny, B. T., Subramaniam, S. and Ahmed, R., Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. J. Exp. Med. 2008. 205: 625–640.
    • (2008) J. Exp. Med. , vol.205 , pp. 625-640
    • Sarkar, S.1    Kalia, V.2    Haining, W.N.3    Konieczny, B.T.4    Subramaniam, S.5    Ahmed, R.6
  • 15
    • 84882603974 scopus 로고    scopus 로고
    • Environmental cues dictate the fate of individual CD8+ T cells responding to infection
    • Plumlee, C. R., Sheridan, B. S., Cicek, B. B. and Lefrancois, L., Environmental cues dictate the fate of individual CD8+ T cells responding to infection. Immunity 2013. 39: 347–356.
    • (2013) Immunity , vol.39 , pp. 347-356
    • Plumlee, C.R.1    Sheridan, B.S.2    Cicek, B.B.3    Lefrancois, L.4
  • 19
    • 84904394259 scopus 로고    scopus 로고
    • Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells
    • Graef, P., Buchholz, V. R., Stemberger, C., Flossdorf, M., Henkel, L., Schiemann, M., Drexler, I. et al., Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells. Immunity 2014. 41: 116–126.
    • (2014) Immunity , vol.41 , pp. 116-126
    • Graef, P.1    Buchholz, V.R.2    Stemberger, C.3    Flossdorf, M.4    Henkel, L.5    Schiemann, M.6    Drexler, I.7
  • 20
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto, F., Lenig, D., Forster, R., Lipp, M. and Lanzavecchia, A., Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999. 401: 708–712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 21
    • 0035937587 scopus 로고    scopus 로고
    • Preferential localization of effector memory cells in nonlymphoid tissue
    • Masopust, D., Vezys, V., Marzo, A. L. and Lefrancois, L., Preferential localization of effector memory cells in nonlymphoid tissue. Science 2001. 291: 2413–2417.
    • (2001) Science , vol.291 , pp. 2413-2417
    • Masopust, D.1    Vezys, V.2    Marzo, A.L.3    Lefrancois, L.4
  • 22
    • 84866735170 scopus 로고    scopus 로고
    • Paths to stemness: building the ultimate antitumour T cell
    • Gattinoni, L., Klebanoff, C. A. and Restifo, N. P., Paths to stemness: building the ultimate antitumour T cell. Nat. Rev. Cancer 2012. 12: 671–684.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 671-684
    • Gattinoni, L.1    Klebanoff, C.A.2    Restifo, N.P.3
  • 24
    • 0038375013 scopus 로고    scopus 로고
    • Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines
    • Geginat, J., Lanzavecchia, A. and Sallusto, F., Proliferation and differentiation potential of human CD8+ memory T-cell subsets in response to antigen or homeostatic cytokines. Blood 2003. 101: 4260–4266.
    • (2003) Blood , vol.101 , pp. 4260-4266
    • Geginat, J.1    Lanzavecchia, A.2    Sallusto, F.3
  • 25
    • 78149278086 scopus 로고    scopus 로고
    • Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence
    • Wakim, L. M., Woodward-Davis, A. and Bevan, M. J., Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence. Proc. Natl. Acad. Sci. USA 2010. 107: 17872–17879.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 17872-17879
    • Wakim, L.M.1    Woodward-Davis, A.2    Bevan, M.J.3
  • 27
    • 84869082967 scopus 로고    scopus 로고
    • A vaccine strategy that protects against genital herpes by establishing local memory T cells
    • Shin, H. and Iwasaki, A., A vaccine strategy that protects against genital herpes by establishing local memory T cells. Nature 2012. 491: 463–467.
    • (2012) Nature , vol.491 , pp. 463-467
    • Shin, H.1    Iwasaki, A.2
  • 28
    • 32044442312 scopus 로고    scopus 로고
    • Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population
    • Masopust, D., Vezys, V., Wherry, E. J., Barber, D. L. and Ahmed, R., Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population. J. Immunol. 2006. 176: 2079–2083.
    • (2006) J. Immunol. , vol.176 , pp. 2079-2083
    • Masopust, D.1    Vezys, V.2    Wherry, E.J.3    Barber, D.L.4    Ahmed, R.5
  • 29
    • 77949506152 scopus 로고    scopus 로고
    • Dynamic T cell migration program provides resident memory within intestinal epithelium
    • Masopust, D., Choo, D., Vezys, V., Wherry, E. J., Duraiswamy, J., Akondy, R., Wang, J. et al., Dynamic T cell migration program provides resident memory within intestinal epithelium. J. Exp. Med. 2010. 207: 553–564.
    • (2010) J. Exp. Med. , vol.207 , pp. 553-564
    • Masopust, D.1    Choo, D.2    Vezys, V.3    Wherry, E.J.4    Duraiswamy, J.5    Akondy, R.6    Wang, J.7
  • 30
    • 84860788997 scopus 로고    scopus 로고
    • Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation
    • Mackay, L. K., Stock, A. T., Ma, J. Z., Jones, C. M., Kent, S. J., Mueller, S. N., Heath, W. R. et al., Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation. Proc. Natl. Acad. Sci. USA 2012. 109: 7037–7042.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 7037-7042
    • Mackay, L.K.1    Stock, A.T.2    Ma, J.Z.3    Jones, C.M.4    Kent, S.J.5    Mueller, S.N.6    Heath, W.R.7
  • 31
    • 84856072398 scopus 로고    scopus 로고
    • Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated CTCL patients
    • Clark, R. A., Watanabe, R., Teague, J. E., Schlapbach, C., Tawa, M. C., Adams, N., Dorosario, A. A. et al., Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated CTCL patients. Sci. Transl. Med. 2012. 4: 117ra117.
    • (2012) Sci. Transl. Med. , vol.4 , pp. 117ra117
    • Clark, R.A.1    Watanabe, R.2    Teague, J.E.3    Schlapbach, C.4    Tawa, M.C.5    Adams, N.6    Dorosario, A.A.7
  • 33
    • 84885863119 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling controls the formation and maintenance of gut-resident memory T cells by regulating migration and retention
    • Zhang, N. and Bevan, M. J., Transforming growth factor-beta signaling controls the formation and maintenance of gut-resident memory T cells by regulating migration and retention. Immunity 2013. 39: 687–696.
    • (2013) Immunity , vol.39 , pp. 687-696
    • Zhang, N.1    Bevan, M.J.2
  • 34
    • 84861163967 scopus 로고    scopus 로고
    • Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues
    • Casey, K. A., Fraser, K. A., Schenkel, J. M., Moran, A., Abt, M. C., Beura, L. K., Lucas, P. J. et al., Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues. J. Immunol. 2012. 188: 4866–4875.
    • (2012) J. Immunol. , vol.188 , pp. 4866-4875
    • Casey, K.A.1    Fraser, K.A.2    Schenkel, J.M.3    Moran, A.4    Abt, M.C.5    Beura, L.K.6    Lucas, P.J.7
  • 35
    • 28644437672 scopus 로고    scopus 로고
    • Host-reactive CD8+ memory stem cells in graft-versus-host disease
    • Zhang, Y., Joe, G., Hexner, E., Zhu, J. and Emerson, S. G., Host-reactive CD8+ memory stem cells in graft-versus-host disease. Nat. Med. 2005. 11: 1299–1305.
    • (2005) Nat. Med. , vol.11 , pp. 1299-1305
    • Zhang, Y.1    Joe, G.2    Hexner, E.3    Zhu, J.4    Emerson, S.G.5
  • 36
    • 27144467425 scopus 로고    scopus 로고
    • Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets
    • Willinger, T., Freeman, T., Hasegawa, H., McMichael, A. J. and Callan, M. F., Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets. J. Immunol. 2005. 175: 5895–5903.
    • (2005) J. Immunol. , vol.175 , pp. 5895-5903
    • Willinger, T.1    Freeman, T.2    Hasegawa, H.3    McMichael, A.J.4    Callan, M.F.5
  • 37
    • 0036884742 scopus 로고    scopus 로고
    • Progressive differentiation and selection of the fittest in the immune response
    • Lanzavecchia, A. and Sallusto, F., Progressive differentiation and selection of the fittest in the immune response. Nat. Rev. Immunol. 2002. 2: 982–987.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 982-987
    • Lanzavecchia, A.1    Sallusto, F.2
  • 38
    • 33745083070 scopus 로고    scopus 로고
    • CD8+ T-cell memory in tumor immunology and immunotherapy
    • Klebanoff, C. A., Gattinoni, L. and Restifo, N. P., CD8+ T-cell memory in tumor immunology and immunotherapy. Immunol. Rev. 2006. 211: 214–224.
    • (2006) Immunol. Rev. , vol.211 , pp. 214-224
    • Klebanoff, C.A.1    Gattinoni, L.2    Restifo, N.P.3
  • 39
    • 84898019055 scopus 로고    scopus 로고
    • Lineage relationship of effector and memory T cells
    • Restifo, N. P. and Gattinoni, L., Lineage relationship of effector and memory T cells. Curr. Opin. Immunol. 2013. 25: 556–563.
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 556-563
    • Restifo, N.P.1    Gattinoni, L.2
  • 40
    • 84875448616 scopus 로고    scopus 로고
    • Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation
    • Best, J. A., Blair, D. A., Knell, J., Yang, E., Mayya, V., Doedens, A., Dustin, M. L. et al., Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation. Nat. Immunol. 2013. 14: 404–412.
    • (2013) Nat. Immunol. , vol.14 , pp. 404-412
    • Best, J.A.1    Blair, D.A.2    Knell, J.3    Yang, E.4    Mayya, V.5    Doedens, A.6    Dustin, M.L.7
  • 42
    • 77952313777 scopus 로고    scopus 로고
    • Differentiation of effector CD4 T cell populations (*)
    • Zhu, J., Yamane, H. and Paul, W. E., Differentiation of effector CD4 T cell populations (*). Annu. Rev. Immunol. 2010. 28: 445–489.
    • (2010) Annu. Rev. Immunol. , vol.28 , pp. 445-489
    • Zhu, J.1    Yamane, H.2    Paul, W.E.3
  • 43
    • 78650947473 scopus 로고    scopus 로고
    • Interplay of transcription factors in T-cell differentiation and function: the role of Runx
    • Wong, W. F., Kohu, K., Chiba, T., Sato, T. and Satake, M., Interplay of transcription factors in T-cell differentiation and function: the role of Runx. Immunology 2011. 132: 157–164.
    • (2011) Immunology , vol.132 , pp. 157-164
    • Wong, W.F.1    Kohu, K.2    Chiba, T.3    Sato, T.4    Satake, M.5
  • 44
    • 80055109080 scopus 로고    scopus 로고
    • Transcriptional control of T-cell development
    • Naito, T., Tanaka, H., Naoe, Y. and Taniuchi, I., Transcriptional control of T-cell development. Int. Immunol. 2011. 23: 661–668.
    • (2011) Int. Immunol. , vol.23 , pp. 661-668
    • Naito, T.1    Tanaka, H.2    Naoe, Y.3    Taniuchi, I.4
  • 45
    • 84911201387 scopus 로고    scopus 로고
    • Molecular regulation of effector and memory T cell differentiation
    • Chang, J. T., Wherry, E. J. and Goldrath, A. W., Molecular regulation of effector and memory T cell differentiation. Nat. Immunol. 2014. 15: 1104–1115.
    • (2014) Nat. Immunol. , vol.15 , pp. 1104-1115
    • Chang, J.T.1    Wherry, E.J.2    Goldrath, A.W.3
  • 46
    • 84867896903 scopus 로고    scopus 로고
    • Transcriptional control of effector and memory CD8+ T cell differentiation
    • Kaech, S. M. and Cui, W., Transcriptional control of effector and memory CD8+ T cell differentiation. Nat. Rev. Immunol. 2012. 12: 749–761.
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 749-761
    • Kaech, S.M.1    Cui, W.2
  • 47
    • 33745345216 scopus 로고    scopus 로고
    • Unidirectional development of CD8+ central memory T cells into protective Listeria-specific effector memory T cells
    • Huster, K. M., Koffler, M., Stemberger, C., Schiemann, M., Wagner, H. and Busch, D. H., Unidirectional development of CD8+ central memory T cells into protective Listeria-specific effector memory T cells. Eur. J. Immunol. 2006. 36: 1453–1464.
    • (2006) Eur. J. Immunol. , vol.36 , pp. 1453-1464
    • Huster, K.M.1    Koffler, M.2    Stemberger, C.3    Schiemann, M.4    Wagner, H.5    Busch, D.H.6
  • 49
    • 34250877389 scopus 로고    scopus 로고
    • Cutting edge: migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells
    • Marzo, A. L., Yagita, H. and Lefrancois, L., Cutting edge: migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells. J. Immunol. 2007. 179: 36–40.
    • (2007) J. Immunol. , vol.179 , pp. 36-40
    • Marzo, A.L.1    Yagita, H.2    Lefrancois, L.3
  • 50
    • 38449086421 scopus 로고    scopus 로고
    • Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation
    • Sarkar, S., Teichgraber, V., Kalia, V., Polley, A., Masopust, D., Harrington, L. E., Ahmed, R. et al., Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation. J. Immunol. 2007. 179: 6704–6714.
    • (2007) J. Immunol. , vol.179 , pp. 6704-6714
    • Sarkar, S.1    Teichgraber, V.2    Kalia, V.3    Polley, A.4    Masopust, D.5    Harrington, L.E.6    Ahmed, R.7
  • 52
    • 77957883572 scopus 로고    scopus 로고
    • Gene regulation by nucleosome positioning
    • Bai, L. and Morozov, A. V., Gene regulation by nucleosome positioning. Trends Genet. 2010. 26: 476–483.
    • (2010) Trends Genet. , vol.26 , pp. 476-483
    • Bai, L.1    Morozov, A.V.2
  • 53
    • 79959557189 scopus 로고    scopus 로고
    • Determinants of nucleosome organization in primary human cells
    • Valouev, A., Johnson, S. M., Boyd, S. D., Smith, C. L., Fire, A. Z. and Sidow, A., Determinants of nucleosome organization in primary human cells. Nature 2011. 474: 516–520.
    • (2011) Nature , vol.474 , pp. 516-520
    • Valouev, A.1    Johnson, S.M.2    Boyd, S.D.3    Smith, C.L.4    Fire, A.Z.5    Sidow, A.6
  • 54
  • 55
    • 15744397041 scopus 로고    scopus 로고
    • Chromatin remodeling complexes: strength in diversity, precision through specialization
    • Cairns, B. R., Chromatin remodeling complexes: strength in diversity, precision through specialization. Curr. Opin. Genet. Dev. 2005. 15: 185–190.
    • (2005) Curr. Opin. Genet. Dev. , vol.15 , pp. 185-190
    • Cairns, B.R.1
  • 56
    • 0037062922 scopus 로고    scopus 로고
    • Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes
    • Chi, T. H., Wan, M., Zhao, K., Taniuchi, I., Chen, L., Littman, D. R. and Crabtree, G. R., Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes. Nature 2002. 418: 195–199.
    • (2002) Nature , vol.418 , pp. 195-199
    • Chi, T.H.1    Wan, M.2    Zhao, K.3    Taniuchi, I.4    Chen, L.5    Littman, D.R.6    Crabtree, G.R.7
  • 57
    • 10244236502 scopus 로고    scopus 로고
    • A BAF-centred view of the immune system
    • Chi, T., A BAF-centred view of the immune system. Nat. Rev. Immunol. 2004. 4: 965–977.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 965-977
    • Chi, T.1
  • 58
    • 33847070442 scopus 로고    scopus 로고
    • The role of chromatin during transcription
    • Li, B., Carey, M. and Workman, J. L., The role of chromatin during transcription. Cell 2007. 128: 707–719.
    • (2007) Cell , vol.128 , pp. 707-719
    • Li, B.1    Carey, M.2    Workman, J.L.3
  • 60
    • 79952534189 scopus 로고    scopus 로고
    • Regulation of chromatin by histone modifications
    • Bannister, A. J. and Kouzarides, T., Regulation of chromatin by histone modifications. Cell. Res. 2011. 21: 381–395.
    • (2011) Cell. Res. , vol.21 , pp. 381-395
    • Bannister, A.J.1    Kouzarides, T.2
  • 61
    • 46249112085 scopus 로고    scopus 로고
    • Combinatorial patterns of histone acetylations and methylations in the human genome
    • Wang, Z., Zang, C., Rosenfeld, J. A., Schones, D. E., Barski, A., Cuddapah, S., Cui, K. et al., Combinatorial patterns of histone acetylations and methylations in the human genome. Nat. Genet. 2008. 40: 897–903.
    • (2008) Nat. Genet. , vol.40 , pp. 897-903
    • Wang, Z.1    Zang, C.2    Rosenfeld, J.A.3    Schones, D.E.4    Barski, A.5    Cuddapah, S.6    Cui, K.7
  • 62
    • 0036211013 scopus 로고    scopus 로고
    • Histone acetylation: a switch between repressive and permissive chromatin. Second in review series on chromatin dynamics
    • Eberharter, A. and Becker, P. B., Histone acetylation: a switch between repressive and permissive chromatin. Second in review series on chromatin dynamics. EMBO Rep. 2002. 3: 224–229.
    • (2002) EMBO Rep. , vol.3 , pp. 224-229
    • Eberharter, A.1    Becker, P.B.2
  • 63
    • 0032030770 scopus 로고    scopus 로고
    • Histone acetylation and transcriptional regulatory mechanisms
    • Struhl, K., Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 1998. 12: 599–606.
    • (1998) Genes Dev. , vol.12 , pp. 599-606
    • Struhl, K.1
  • 65
    • 84863986133 scopus 로고    scopus 로고
    • Functions of DNA methylation: islands, start sites, gene bodies and beyond
    • Jones, P. A., Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat. Rev. Genet. 2012. 13: 484–492.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 484-492
    • Jones, P.A.1
  • 66
    • 84878260646 scopus 로고    scopus 로고
    • TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
    • Pastor, W. A., Aravind, L. and Rao, A., TETonic shift: biological roles of TET proteins in DNA demethylation and transcription. Nat. Rev. Mol. Cell Biol. 2013. 14: 341–356.
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 341-356
    • Pastor, W.A.1    Aravind, L.2    Rao, A.3
  • 67
    • 66149146320 scopus 로고    scopus 로고
    • Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
    • Tahiliani, M., Koh, K. P., Shen, Y., Pastor, W. A., Bandukwala, H., Brudno, Y., Agarwal, S. et al., Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 2009. 324: 930–935.
    • (2009) Science , vol.324 , pp. 930-935
    • Tahiliani, M.1    Koh, K.P.2    Shen, Y.3    Pastor, W.A.4    Bandukwala, H.5    Brudno, Y.6    Agarwal, S.7
  • 69
    • 0037087576 scopus 로고    scopus 로고
    • Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors
    • Katan-Khaykovich, Y. and Struhl, K., Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors. Genes Dev. 2002. 16: 743–752.
    • (2002) Genes Dev. , vol.16 , pp. 743-752
    • Katan-Khaykovich, Y.1    Struhl, K.2
  • 70
    • 84888994574 scopus 로고    scopus 로고
    • Cross-talk between site-specific transcription factors and DNA methylation states
    • Blattler, A. and Farnham, P. J., Cross-talk between site-specific transcription factors and DNA methylation states. J. Biol. Chem. 2013. 288: 34287–34294.
    • (2013) J. Biol. Chem. , vol.288 , pp. 34287-34294
    • Blattler, A.1    Farnham, P.J.2
  • 71
    • 33745811234 scopus 로고    scopus 로고
    • The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells
    • Li, H., Rauch, T., Chen, Z. X., Szabo, P. E., Riggs, A. D. and Pfeifer, G. P., The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells. J. Biol. Chem. 2006. 281: 19489–19500.
    • (2006) J. Biol. Chem. , vol.281 , pp. 19489-19500
    • Li, H.1    Rauch, T.2    Chen, Z.X.3    Szabo, P.E.4    Riggs, A.D.5    Pfeifer, G.P.6
  • 73
    • 78049414227 scopus 로고    scopus 로고
    • Epigenetic reprogramming in plant and animal development
    • Feng, S., Jacobsen, S. E. and Reik, W., Epigenetic reprogramming in plant and animal development. Science 2010. 330: 622–627.
    • (2010) Science , vol.330 , pp. 622-627
    • Feng, S.1    Jacobsen, S.E.2    Reik, W.3
  • 74
    • 84874194072 scopus 로고    scopus 로고
    • DNA methylation: roles in mammalian development
    • Smith, Z. D. and Meissner, A., DNA methylation: roles in mammalian development. Nat. Rev. Genet. 2013. 14: 204–220.
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 204-220
    • Smith, Z.D.1    Meissner, A.2
  • 75
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
    • Jaenisch, R. and Bird, A., Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 2003. 33 (Suppl): 245–254.
    • (2003) Nat. Genet. , vol.33 , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 76
    • 84862824246 scopus 로고    scopus 로고
    • Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol
    • Chen, Y. F., Tseng, C. Y., Wang, H. W., Kuo, H. C., Yang, V. W. and Lee, O. K., Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol. Hepatology 2012. 55: 1193–1203.
    • (2012) Hepatology , vol.55 , pp. 1193-1203
    • Chen, Y.F.1    Tseng, C.Y.2    Wang, H.W.3    Kuo, H.C.4    Yang, V.W.5    Lee, O.K.6
  • 77
    • 84355166561 scopus 로고    scopus 로고
    • Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
    • Kriks, S., Shim, J. W., Piao, J., Ganat, Y. M., Wakeman, D. R., Xie, Z., Carrillo-Reid, L. et al., Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 2011. 480: 547–551.
    • (2011) Nature , vol.480 , pp. 547-551
    • Kriks, S.1    Shim, J.W.2    Piao, J.3    Ganat, Y.M.4    Wakeman, D.R.5    Xie, Z.6    Carrillo-Reid, L.7
  • 78
    • 84861937125 scopus 로고    scopus 로고
    • One-step derivation of cardiomyocytes and mesenchymal stem cells from human pluripotent stem cells
    • Wei, H., Tan, G., Manasi, Qiu, S., Kong, G., Yong, P., Koh, C. et al., One-step derivation of cardiomyocytes and mesenchymal stem cells from human pluripotent stem cells. Stem Cell Res. 2012. 9: 87–100.
    • (2012) Stem Cell Res. , vol.9 , pp. 87-100
    • Wei, H.1    Tan, G.2    Manasi3    Qiu, S.4    Kong, G.5    Yong, P.6    Koh, C.7
  • 79
    • 84878292277 scopus 로고    scopus 로고
    • Transcriptional and epigenetic dynamics during specification of human embryonic stem cells
    • Gifford, C. A., Ziller, M. J., Gu, H., Trapnell, C., Donaghey, J., Tsankov, A., Shalek, A. K. et al., Transcriptional and epigenetic dynamics during specification of human embryonic stem cells. Cell 2013. 153: 1149–1163.
    • (2013) Cell , vol.153 , pp. 1149-1163
    • Gifford, C.A.1    Ziller, M.J.2    Gu, H.3    Trapnell, C.4    Donaghey, J.5    Tsankov, A.6    Shalek, A.K.7
  • 80
    • 35348982301 scopus 로고    scopus 로고
    • Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
    • Loh, Y. H., Zhang, W., Chen, X., George, J. and Ng, H. H., Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. Genes Dev. 2007. 21: 2545–2557.
    • (2007) Genes Dev. , vol.21 , pp. 2545-2557
    • Loh, Y.H.1    Zhang, W.2    Chen, X.3    George, J.4    Ng, H.H.5
  • 81
    • 33745865934 scopus 로고    scopus 로고
    • Chromatin in pluripotent embryonic stem cells and differentiation
    • Meshorer, E. and Misteli, T., Chromatin in pluripotent embryonic stem cells and differentiation. Nat. Rev. Mol. Cell Biol. 2006. 7: 540–546.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 540-546
    • Meshorer, E.1    Misteli, T.2
  • 82
    • 4944245398 scopus 로고    scopus 로고
    • Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
    • Vaquero, A., Scher, M., Lee, D., Erdjument-Bromage, H., Tempst, P. and Reinberg, D., Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol. Cell 2004. 16: 93–105.
    • (2004) Mol. Cell , vol.16 , pp. 93-105
    • Vaquero, A.1    Scher, M.2    Lee, D.3    Erdjument-Bromage, H.4    Tempst, P.5    Reinberg, D.6
  • 83
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein, B. E., Mikkelsen, T. S., Xie, X., Kamal, M., Huebert, D. J., Cuff, J., Fry, B. et al., A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 2006. 125: 315–326.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3    Kamal, M.4    Huebert, D.J.5    Cuff, J.6    Fry, B.7
  • 84
    • 67349169780 scopus 로고    scopus 로고
    • Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells
    • Araki, Y., Wang, Z., Zang, C., Wood, W. H., 3rd, Schones, D., Cui, K., Roh, T. Y. et al., Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8+ T cells. Immunity 2009. 30: 912–925.
    • (2009) Immunity , vol.30 , pp. 912-925
    • Araki, Y.1    Wang, Z.2    Zang, C.3    Wood, W.H.4    Schones, D.5    Cui, K.6    Roh, T.Y.7
  • 87
    • 0036145567 scopus 로고    scopus 로고
    • Dynamic reprogramming of DNA methylation in the early mouse embryo
    • Santos, F., Hendrich, B., Reik, W. and Dean, W., Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev. Biol. 2002. 241: 172–182.
    • (2002) Dev. Biol. , vol.241 , pp. 172-182
    • Santos, F.1    Hendrich, B.2    Reik, W.3    Dean, W.4
  • 88
    • 84978291409 scopus 로고    scopus 로고
    • The epigenetics of embryo development
    • O'Neill, C., The epigenetics of embryo development. Anim. Front. 2015. 5: 42–49.
    • (2015) Anim. Front. , vol.5 , pp. 42-49
    • O'Neill, C.1
  • 89
    • 84900300766 scopus 로고    scopus 로고
    • Programming and inheritance of parental DNA methylomes in mammals
    • Wang, L., Zhang, J., Duan, J., Gao, X., Zhu, W., Lu, X., Yang, L. et al., Programming and inheritance of parental DNA methylomes in mammals. Cell 2014. 157: 979–991.
    • (2014) Cell , vol.157 , pp. 979-991
    • Wang, L.1    Zhang, J.2    Duan, J.3    Gao, X.4    Zhu, W.5    Lu, X.6    Yang, L.7
  • 90
    • 58149088296 scopus 로고    scopus 로고
    • Dynamic transition of Dnmt3b expression in mouse pre- and early post-implantation embryos
    • Hirasawa, R. and Sasaki, H., Dynamic transition of Dnmt3b expression in mouse pre- and early post-implantation embryos. Gene Expr. Patterns 2009. 9: 27–30.
    • (2009) Gene Expr. Patterns , vol.9 , pp. 27-30
    • Hirasawa, R.1    Sasaki, H.2
  • 91
    • 0042132027 scopus 로고    scopus 로고
    • Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
    • Chen, T., Ueda, Y., Dodge, J. E., Wang, Z. and Li, E., Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol. Cell Biol. 2003. 23: 5594–5605.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 5594-5605
    • Chen, T.1    Ueda, Y.2    Dodge, J.E.3    Wang, Z.4    Li, E.5
  • 92
    • 4744372577 scopus 로고    scopus 로고
    • Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells
    • Jackson, M., Krassowska, A., Gilbert, N., Chevassut, T., Forrester, L., Ansell, J. and Ramsahoye, B., Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol. Cell Biol. 2004. 24: 8862–8871.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 8862-8871
    • Jackson, M.1    Krassowska, A.2    Gilbert, N.3    Chevassut, T.4    Forrester, L.5    Ansell, J.6    Ramsahoye, B.7
  • 93
    • 33847293264 scopus 로고    scopus 로고
    • Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
    • Chen, T., Hevi, S., Gay, F., Tsujimoto, N., He, T., Zhang, B., Ueda, Y. et al., Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells. Nat. Genet. 2007. 39: 391–396.
    • (2007) Nat. Genet. , vol.39 , pp. 391-396
    • Chen, T.1    Hevi, S.2    Gay, F.3    Tsujimoto, N.4    He, T.5    Zhang, B.6    Ueda, Y.7
  • 94
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li, E., Bestor, T. H. and Jaenisch, R., Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992. 69: 915–926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 95
    • 84857160311 scopus 로고    scopus 로고
    • Trophoblast-specific DNA methylation occurs after the segregation of the trophectoderm and inner cell mass in the mouse periimplantation embryo
    • Nakanishi, M. O., Hayakawa, K., Nakabayashi, K., Hata, K., Shiota, K. and Tanaka, S., Trophoblast-specific DNA methylation occurs after the segregation of the trophectoderm and inner cell mass in the mouse periimplantation embryo. Epigenetics 2012. 7: 173–182.
    • (2012) Epigenetics , vol.7 , pp. 173-182
    • Nakanishi, M.O.1    Hayakawa, K.2    Nakabayashi, K.3    Hata, K.4    Shiota, K.5    Tanaka, S.6
  • 96
    • 84921468426 scopus 로고    scopus 로고
    • Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation
    • Mayle, A., Yang, L., Rodriguez, B., Zhou, T., Chang, E., Curry, C. V., Challen, G. A. et al., Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation. Blood 2015. 125: 629–638.
    • (2015) Blood , vol.125 , pp. 629-638
    • Mayle, A.1    Yang, L.2    Rodriguez, B.3    Zhou, T.4    Chang, E.5    Curry, C.V.6    Challen, G.A.7
  • 97
    • 70349469788 scopus 로고    scopus 로고
    • DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
    • Trowbridge, J. J., Snow, J. W., Kim, J. and Orkin, S. H., DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell 2009. 5: 442–449.
    • (2009) Cell Stem Cell , vol.5 , pp. 442-449
    • Trowbridge, J.J.1    Snow, J.W.2    Kim, J.3    Orkin, S.H.4
  • 98
    • 70350654370 scopus 로고    scopus 로고
    • DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
    • Broske, A. M., Vockentanz, L., Kharazi, S., Huska, M. R., Mancini, E., Scheller, M., Kuhl, C. et al., DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat. Genet. 2009. 41: 1207–1215.
    • (2009) Nat. Genet. , vol.41 , pp. 1207-1215
    • Broske, A.M.1    Vockentanz, L.2    Kharazi, S.3    Huska, M.R.4    Mancini, E.5    Scheller, M.6    Kuhl, C.7
  • 100
    • 79960062301 scopus 로고    scopus 로고
    • TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
    • Quivoron, C., Couronne, L., Della Valle, V., Lopez, C. K., Plo, I., Wagner-Ballon, O., Do Cruzeiro, M. et al., TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 2011. 20: 25–38.
    • (2011) Cancer Cell , vol.20 , pp. 25-38
    • Quivoron, C.1    Couronne, L.2    Della Valle, V.3    Lopez, C.K.4    Plo, I.5    Wagner-Ballon, O.6    Do Cruzeiro, M.7
  • 101
    • 80052284526 scopus 로고    scopus 로고
    • Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
    • Ko, M., Bandukwala, H. S., An, J., Lamperti, E. D., Thompson, E. C., Hastie, R., Tsangaratou, A. et al., Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proc. Natl. Acad. Sci. USA 2011. 108: 14566–14571.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 14566-14571
    • Ko, M.1    Bandukwala, H.S.2    An, J.3    Lamperti, E.D.4    Thompson, E.C.5    Hastie, R.6    Tsangaratou, A.7
  • 102
    • 78650019179 scopus 로고    scopus 로고
    • Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
    • Figueroa, M. E., Abdel-Wahab, O., Lu, C., Ward, P. S., Patel, J., Shih, A., Li, Y. et al., Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 2010. 18: 553–567.
    • (2010) Cancer Cell , vol.18 , pp. 553-567
    • Figueroa, M.E.1    Abdel-Wahab, O.2    Lu, C.3    Ward, P.S.4    Patel, J.5    Shih, A.6    Li, Y.7
  • 103
    • 84897995314 scopus 로고    scopus 로고
    • An epigenetic profile of early T-cell development from multipotent progenitors to committed T-cell descendants
    • Vigano, M. A., Ivanek, R., Balwierz, P., Berninger, P., van Nimwegen, E., Karjalainen, K. and Rolink, A., An epigenetic profile of early T-cell development from multipotent progenitors to committed T-cell descendants. Eur. J. Immunol. 2014. 44: 1181–1193.
    • (2014) Eur. J. Immunol. , vol.44 , pp. 1181-1193
    • Vigano, M.A.1    Ivanek, R.2    Balwierz, P.3    Berninger, P.4    van Nimwegen, E.5    Karjalainen, K.6    Rolink, A.7
  • 105
    • 18244365863 scopus 로고    scopus 로고
    • A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
    • Lee, P. P., Fitzpatrick, D. R., Beard, C., Jessup, H. K., Lehar, S., Makar, K. W., Perez-Melgosa, M. et al., A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 2001. 15: 763–774.
    • (2001) Immunity , vol.15 , pp. 763-774
    • Lee, P.P.1    Fitzpatrick, D.R.2    Beard, C.3    Jessup, H.K.4    Lehar, S.5    Makar, K.W.6    Perez-Melgosa, M.7
  • 107
    • 58849088509 scopus 로고    scopus 로고
    • T-bet dependent removal of Sin3A-histone deacetylase complexes at the Ifng locus drives Th1 differentiation
    • Chang, S., Collins, P. L. and Aune, T. M., T-bet dependent removal of Sin3A-histone deacetylase complexes at the Ifng locus drives Th1 differentiation. J. Immunol. 2008. 181: 8372–8381.
    • (2008) J. Immunol. , vol.181 , pp. 8372-8381
    • Chang, S.1    Collins, P.L.2    Aune, T.M.3
  • 109
    • 4644231710 scopus 로고    scopus 로고
    • DNA methylation is a nonredundant repressor of the Th2 effector program
    • Makar, K. W. and Wilson, C. B., DNA methylation is a nonredundant repressor of the Th2 effector program. J. Immunol. 2004. 173: 4402–4406.
    • (2004) J. Immunol. , vol.173 , pp. 4402-4406
    • Makar, K.W.1    Wilson, C.B.2
  • 110
    • 76749133610 scopus 로고    scopus 로고
    • Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
    • Zheng, Y., Josefowicz, S., Chaudhry, A., Peng, X. P., Forbush, K. and Rudensky, A. Y., Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 2010. 463: 808–812.
    • (2010) Nature , vol.463 , pp. 808-812
    • Zheng, Y.1    Josefowicz, S.2    Chaudhry, A.3    Peng, X.P.4    Forbush, K.5    Rudensky, A.Y.6
  • 111
    • 33644854871 scopus 로고    scopus 로고
    • A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory
    • Murayama, A., Sakura, K., Nakama, M., Yasuzawa-Tanaka, K., Fujita, E., Tateishi, Y., Wang, Y. et al., A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory. EMBO J. 2006. 25: 1081–1092.
    • (2006) EMBO J. , vol.25 , pp. 1081-1092
    • Murayama, A.1    Sakura, K.2    Nakama, M.3    Yasuzawa-Tanaka, K.4    Fujita, E.5    Tateishi, Y.6    Wang, Y.7
  • 112
    • 33645770934 scopus 로고    scopus 로고
    • DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion
    • Chappell, C., Beard, C., Altman, J., Jaenisch, R. and Jacob, J., DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion. J. Immunol. 2006. 176: 4562–4572.
    • (2006) J. Immunol. , vol.176 , pp. 4562-4572
    • Chappell, C.1    Beard, C.2    Altman, J.3    Jaenisch, R.4    Jacob, J.5
  • 113
    • 84931301873 scopus 로고    scopus 로고
    • DNA methylation secures CD4(+) and CD8(+) T cell lineage borders
    • Feng, Y. and Rudensky, A. Y., DNA methylation secures CD4(+) and CD8(+) T cell lineage borders. Nat. Immunol. 2015. 16: 681–683.
    • (2015) Nat. Immunol. , vol.16 , pp. 681-683
    • Feng, Y.1    Rudensky, A.Y.2
  • 114
    • 84931327865 scopus 로고    scopus 로고
    • Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages
    • Sellars, M., Huh, J. R., Day, K., Issuree, P. D., Galan, C., Gobeil, S., Absher, D. et al., Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages. Nat. Immunol. 2015. 16: 746–754.
    • (2015) Nat. Immunol. , vol.16 , pp. 746-754
    • Sellars, M.1    Huh, J.R.2    Day, K.3    Issuree, P.D.4    Galan, C.5    Gobeil, S.6    Absher, D.7
  • 115
    • 65549100376 scopus 로고    scopus 로고
    • Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1
    • Josefowicz, S. Z., Wilson, C. B. and Rudensky, A. Y., Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1. J. Immunol. 2009. 182: 6648–6652.
    • (2009) J. Immunol. , vol.182 , pp. 6648-6652
    • Josefowicz, S.Z.1    Wilson, C.B.2    Rudensky, A.Y.3
  • 116
    • 80053086090 scopus 로고    scopus 로고
    • Differentiation-dependent functional and epigenetic landscapes for cytokine genes in virus-specific CD8+ T cells
    • Denton, A. E., Russ, B. E., Doherty, P. C., Rao, S. and Turner, S. J., Differentiation-dependent functional and epigenetic landscapes for cytokine genes in virus-specific CD8+ T cells. Proc. Natl. Acad. Sci. USA 2011. 108: 15306–15311.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 15306-15311
    • Denton, A.E.1    Russ, B.E.2    Doherty, P.C.3    Rao, S.4    Turner, S.J.5
  • 117
    • 73349112246 scopus 로고    scopus 로고
    • Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression
    • Juelich, T., Sutcliffe, E. L., Denton, A., He, Y., Doherty, P. C., Parish, C. R., Turner, S. J. et al., Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression. J. Immunol. 2009. 183: 7063–7072.
    • (2009) J. Immunol. , vol.183 , pp. 7063-7072
    • Juelich, T.1    Sutcliffe, E.L.2    Denton, A.3    He, Y.4    Doherty, P.C.5    Parish, C.R.6    Turner, S.J.7
  • 118
    • 79952756708 scopus 로고    scopus 로고
    • Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status
    • Zediak, V. P., Johnnidis, J. B., Wherry, E. J. and Berger, S. L., Cutting edge: persistently open chromatin at effector gene loci in resting memory CD8+ T cells independent of transcriptional status. J. Immunol. 2011. 186: 2705–2709.
    • (2011) J. Immunol. , vol.186 , pp. 2705-2709
    • Zediak, V.P.1    Johnnidis, J.B.2    Wherry, E.J.3    Berger, S.L.4
  • 119
    • 33745861718 scopus 로고    scopus 로고
    • Epigenetic remodeling of the IL-2 and IFN-gamma loci in memory CD8 T cells is influenced by CD4 T cells
    • Northrop, J. K., Thomas, R. M., Wells, A. D. and Shen, H., Epigenetic remodeling of the IL-2 and IFN-gamma loci in memory CD8 T cells is influenced by CD4 T cells. J. Immunol. 2006. 177: 1062–1069.
    • (2006) J. Immunol. , vol.177 , pp. 1062-1069
    • Northrop, J.K.1    Thomas, R.M.2    Wells, A.D.3    Shen, H.4
  • 120
    • 49049110982 scopus 로고    scopus 로고
    • Cutting edge: chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells
    • Northrop, J. K., Wells, A. D. and Shen, H., Cutting edge: chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells. J. Immunol. 2008. 181: 865–868.
    • (2008) J. Immunol. , vol.181 , pp. 865-868
    • Northrop, J.K.1    Wells, A.D.2    Shen, H.3
  • 121
    • 50949127683 scopus 로고    scopus 로고
    • Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B)
    • Araki, Y., Fann, M., Wersto, R. and Weng, N. P., Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B). J. Immunol. 2008. 180: 8102–8108.
    • (2008) J. Immunol. , vol.180 , pp. 8102-8108
    • Araki, Y.1    Fann, M.2    Wersto, R.3    Weng, N.P.4
  • 122
    • 84912096136 scopus 로고    scopus 로고
    • Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8(+) T cell differentiation
    • Russ, B. E., Olshanksy, M., Smallwood, H. S., Li, J., Denton, A. E., Prier, J. E., Stock, A. T. et al., Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8(+) T cell differentiation. Immunity 2014. 41: 853–865.
    • (2014) Immunity , vol.41 , pp. 853-865
    • Russ, B.E.1    Olshanksy, M.2    Smallwood, H.S.3    Li, J.4    Denton, A.E.5    Prier, J.E.6    Stock, A.T.7
  • 124
    • 84956825522 scopus 로고    scopus 로고
    • Dynamic regulation of permissive histone modifications and GATA3 binding underpin acquisition of granzyme A expression by virus-specific CD8(+) T cells
    • Nguyen, M. L., Hatton, L., Li, J., Olshansky, M., Kelso, A., Russ, B. E. and Turner, S. J., Dynamic regulation of permissive histone modifications and GATA3 binding underpin acquisition of granzyme A expression by virus-specific CD8(+) T cells. Eur. J. Immunol. 2016. 46: 307–318.
    • (2016) Eur. J. Immunol. , vol.46 , pp. 307-318
    • Nguyen, M.L.1    Hatton, L.2    Li, J.3    Olshansky, M.4    Kelso, A.5    Russ, B.E.6    Turner, S.J.7
  • 125
    • 84928019813 scopus 로고    scopus 로고
    • Memory CD8 T cell transcriptional plasticity
    • Youngblood, B., Hale, J. S. and Ahmed, R., Memory CD8 T cell transcriptional plasticity. F1000Prime Rep. 2015. 7: 38.
    • (2015) F1000Prime Rep. , vol.7 , pp. 38
    • Youngblood, B.1    Hale, J.S.2    Ahmed, R.3
  • 126
    • 84905984263 scopus 로고    scopus 로고
    • The interface between transcriptional and epigenetic control of effector and memory CD8(+) T-cell differentiation
    • Gray, S. M., Kaech, S. M. and Staron, M. M., The interface between transcriptional and epigenetic control of effector and memory CD8(+) T-cell differentiation. Immunol. Rev. 2014. 261: 157–168.
    • (2014) Immunol. Rev. , vol.261 , pp. 157-168
    • Gray, S.M.1    Kaech, S.M.2    Staron, M.M.3
  • 128
    • 84884256121 scopus 로고    scopus 로고
    • Global DNA methylation remodeling accompanies CD8 T cell effector function
    • Scharer, C. D., Barwick, B. G., Youngblood, B. A., Ahmed, R. and Boss, J. M., Global DNA methylation remodeling accompanies CD8 T cell effector function. J. Immunol. 2013. 191: 3419–3429.
    • (2013) J. Immunol. , vol.191 , pp. 3419-3429
    • Scharer, C.D.1    Barwick, B.G.2    Youngblood, B.A.3    Ahmed, R.4    Boss, J.M.5
  • 129
    • 84879211454 scopus 로고    scopus 로고
    • T-cell memory differentiation: insights from transcriptional signatures and epigenetics
    • Youngblood, B., Hale, J. S. and Ahmed, R., T-cell memory differentiation: insights from transcriptional signatures and epigenetics. Immunology 2013. 139: 277–284.
    • (2013) Immunology , vol.139 , pp. 277-284
    • Youngblood, B.1    Hale, J.S.2    Ahmed, R.3
  • 131
    • 0037383592 scopus 로고    scopus 로고
    • Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment
    • Wherry, E. J., Blattman, J. N., Murali-Krishna, K., van der Most, R. and Ahmed, R., Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J. Virol. 2003. 77: 4911–4927.
    • (2003) J. Virol. , vol.77 , pp. 4911-4927
    • Wherry, E.J.1    Blattman, J.N.2    Murali-Krishna, K.3    van der Most, R.4    Ahmed, R.5
  • 132
    • 70349569569 scopus 로고    scopus 로고
    • Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
    • Ahmadzadeh, M., Johnson, L. A., Heemskerk, B., Wunderlich, J. R., Dudley, M. E., White, D. E. and Rosenberg, S. A., Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood 2009. 114: 1537–1544.
    • (2009) Blood , vol.114 , pp. 1537-1544
    • Ahmadzadeh, M.1    Johnson, L.A.2    Heemskerk, B.3    Wunderlich, J.R.4    Dudley, M.E.5    White, D.E.6    Rosenberg, S.A.7
  • 133
    • 70349562580 scopus 로고    scopus 로고
    • Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression
    • Mumprecht, S., Schurch, C., Schwaller, J., Solenthaler, M. and Ochsenbein, A. F., Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression. Blood 2009. 114: 1528–1536.
    • (2009) Blood , vol.114 , pp. 1528-1536
    • Mumprecht, S.1    Schurch, C.2    Schwaller, J.3    Solenthaler, M.4    Ochsenbein, A.F.5
  • 134
    • 84941745031 scopus 로고    scopus 로고
    • Magnitude and kinetics of CD8+ T cell activation during hyperacute HIV infection impact viral set point
    • Ndhlovu, Z. M., Kamya, P., Mewalal, N., Kloverpris, H. N., Nkosi, T., Pretorius, K., Laher, F. et al., Magnitude and kinetics of CD8+ T cell activation during hyperacute HIV infection impact viral set point. Immunity 2015. 43: 591–604.
    • (2015) Immunity , vol.43 , pp. 591-604
    • Ndhlovu, Z.M.1    Kamya, P.2    Mewalal, N.3    Kloverpris, H.N.4    Nkosi, T.5    Pretorius, K.6    Laher, F.7
  • 135
    • 84937837169 scopus 로고    scopus 로고
    • Molecular and cellular insights into T cell exhaustion
    • Wherry, E. J. and Kurachi, M., Molecular and cellular insights into T cell exhaustion. Nat. Rev. Immunol. 2015. 15: 486–499.
    • (2015) Nat. Rev. Immunol. , vol.15 , pp. 486-499
    • Wherry, E.J.1    Kurachi, M.2
  • 136
    • 84926528302 scopus 로고    scopus 로고
    • Overcoming T cell exhaustion in infection and cancer
    • Pauken, K. E. and Wherry, E. J., Overcoming T cell exhaustion in infection and cancer. Trends Immunol. 2015. 36: 265–276.
    • (2015) Trends Immunol. , vol.36 , pp. 265-276
    • Pauken, K.E.1    Wherry, E.J.2
  • 138
    • 84857059757 scopus 로고    scopus 로고
    • Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells
    • Youngblood, B., Wherry, E. J. and Ahmed, R., Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells. Curr. Opin. HIV AIDS 2012. 7: 50–57.
    • (2012) Curr. Opin. HIV AIDS , vol.7 , pp. 50-57
    • Youngblood, B.1    Wherry, E.J.2    Ahmed, R.3
  • 139
    • 84864378851 scopus 로고    scopus 로고
    • Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection
    • Angelosanto, J. M., Blackburn, S. D., Crawford, A. and Wherry, E. J., Progressive loss of memory T cell potential and commitment to exhaustion during chronic viral infection. J. Virol. 2012. 86: 8161–8170.
    • (2012) J. Virol. , vol.86 , pp. 8161-8170
    • Angelosanto, J.M.1    Blackburn, S.D.2    Crawford, A.3    Wherry, E.J.4
  • 141
    • 80053137239 scopus 로고    scopus 로고
    • Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells
    • Youngblood, B., Oestreich, K. J., Ha, S. J., Duraiswamy, J., Akondy, R. S., West, E. E., Wei, Z. et al., Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells. Immunity 2011. 35: 400–412.
    • (2011) Immunity , vol.35 , pp. 400-412
    • Youngblood, B.1    Oestreich, K.J.2    Ha, S.J.3    Duraiswamy, J.4    Akondy, R.S.5    West, E.E.6    Wei, Z.7
  • 142
    • 84880119204 scopus 로고    scopus 로고
    • Cutting edge: prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells
    • Youngblood, B., Noto, A., Porichis, F., Akondy, R. S., Ndhlovu, Z. M., Austin, J. W., Bordi, R. et al., Cutting edge: prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells. J. Immunol. 2013. 191: 540–544.
    • (2013) J. Immunol. , vol.191 , pp. 540-544
    • Youngblood, B.1    Noto, A.2    Porichis, F.3    Akondy, R.S.4    Ndhlovu, Z.M.5    Austin, J.W.6    Bordi, R.7
  • 143
    • 84859403357 scopus 로고    scopus 로고
    • Inhibitory receptors on lymphocytes: insights from infections
    • Odorizzi, P. M. and Wherry, E. J., Inhibitory receptors on lymphocytes: insights from infections. J. Immunol. 2012. 188: 2957–2965.
    • (2012) J. Immunol. , vol.188 , pp. 2957-2965
    • Odorizzi, P.M.1    Wherry, E.J.2
  • 144
    • 77954956266 scopus 로고    scopus 로고
    • Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8(+) T cell differentiation
    • Wirth, T. C., Xue, H. H., Rai, D., Sabel, J. T., Bair, T., Harty, J. T. and Badovinac, V. P., Repetitive antigen stimulation induces stepwise transcriptome diversification but preserves a core signature of memory CD8(+) T cell differentiation. Immunity 2010. 33: 128–140.
    • (2010) Immunity , vol.33 , pp. 128-140
    • Wirth, T.C.1    Xue, H.H.2    Rai, D.3    Sabel, J.T.4    Bair, T.5    Harty, J.T.6    Badovinac, V.P.7
  • 145
    • 33745810216 scopus 로고    scopus 로고
    • Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination
    • Masopust, D., Ha, S. J., Vezys, V. and Ahmed, R., Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination. J. Immunol. 2006. 177: 831–839.
    • (2006) J. Immunol. , vol.177 , pp. 831-839
    • Masopust, D.1    Ha, S.J.2    Vezys, V.3    Ahmed, R.4


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