-
1
-
-
0037154963
-
Cooperation between complexes that regulate chromatin structure and transcription
-
G.J. Narlikar, H.Y. Fan, and R.E. Kingston Cooperation between complexes that regulate chromatin structure and transcription Cell 108 2002 475 487
-
(2002)
Cell
, vol.108
, pp. 475-487
-
-
Narlikar, G.J.1
Fan, H.Y.2
Kingston, R.E.3
-
2
-
-
1542358189
-
Multiple roles for ISWI in transcription, chromosome organization and DNA replication
-
D.F. Corona, and J.W. Tamkun Multiple roles for ISWI in transcription, chromosome organization and DNA replication Biochem Biophys Acta 1677 2004 113 119
-
(2004)
Biochem Biophys Acta
, vol.1677
, pp. 113-119
-
-
Corona, D.F.1
Tamkun, J.W.2
-
3
-
-
0036299092
-
The histone variant H3.3 marks active chromatin by replication- independent nucleosome assembly
-
K. Ahmad, and S. Henikoff The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly Mol Cell 9 2002 1191 1200
-
(2002)
Mol Cell
, vol.9
, pp. 1191-1200
-
-
Ahmad, K.1
Henikoff, S.2
-
4
-
-
0037423930
-
Conserved histone variant H2A.Z protects euchromatin from the ectopic spread of silent heterochromatin
-
M.D. Meneghini, M. Wu, and H.D. Madhani Conserved histone variant H2A.Z protects euchromatin from the ectopic spread of silent heterochromatin Cell 112 2003 725 736 Transcription profiling of htz1Δ nulls revealed the silencing of genes near certain telomeres and genes near the silent mating-type cassettes. This silencing was correlated with the acquired occupancy of Sir3, which is likely to have spread from silent telomeres/cassettes. This study was the first to show a role for Htz1 in the formation of a boundary to silent heterochromatin.
-
(2003)
Cell
, vol.112
, pp. 725-736
-
-
Meneghini, M.D.1
Wu, M.2
Madhani, H.D.3
-
5
-
-
0035725036
-
H2A.Z is required for global chromatin integrity and for recruitment of RNA polymerase II under specific conditions
-
M. Adam, F. Robert, M. Larochelle, and L. Gaudreau H2A.Z is required for global chromatin integrity and for recruitment of RNA polymerase II under specific conditions Mol Cell Biol 21 2001 6270 6279
-
(2001)
Mol Cell Biol
, vol.21
, pp. 6270-6279
-
-
Adam, M.1
Robert, F.2
Larochelle, M.3
Gaudreau, L.4
-
6
-
-
0034721645
-
Histone H2A.Z regulates transcription and is partially redundant with nucleosome remodeling complexes
-
M.S. Santisteban, T. Kalashnikova, and M.M. Smith Histone H2A.Z regulates transcription and is partially redundant with nucleosome remodeling complexes Cell 103 2000 411 422
-
(2000)
Cell
, vol.103
, pp. 411-422
-
-
Santisteban, M.S.1
Kalashnikova, T.2
Smith, M.M.3
-
7
-
-
9144269660
-
A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1
-
••].
-
(2003)
Mol Cell
, vol.12
, pp. 1565-1576
-
-
Krogan, N.J.1
Keogh, M.C.2
Datta, N.3
Sawa, C.4
Ryan, O.W.5
Ding, H.6
Haw, R.A.7
Pootoolal, J.8
Tong, A.9
Canadien, V.10
-
9
-
-
19344372948
-
A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin
-
•• ] provide an important set of work establishing the SWR1 complex as the histone H2A.Z variant Htz1 exchanger. All three papers provide a purification of the complex, identification of the subunits, genetic evidence for the function of Swr1 in replacement and chromatin immunoprecipitation experiments to monitor Htz1 replacement at particular genes. This study also provides connections to the NuA4 HAT in this process.
-
(2004)
PLoS Biol
, vol.2
, pp. 131
-
-
Kobor, M.S.1
Venkatasubrahmanyam, S.2
Meneghini, M.D.3
Gin, J.W.4
Jennings, J.L.5
Link, A.J.6
Madhani, H.D.7
Rine, J.8
-
10
-
-
0037102562
-
Chromatin remodeling by RSC involves ATP-dependent DNA translocation
-
A. Saha, J. Wittmeyer, and B.R. Cairns Chromatin remodeling by RSC involves ATP-dependent DNA translocation Genes Dev 16 2002 2120 2134
-
(2002)
Genes Dev
, vol.16
, pp. 2120-2134
-
-
Saha, A.1
Wittmeyer, J.2
Cairns, B.R.3
-
11
-
-
0037370303
-
Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme
-
I. Whitehouse, C. Stockdale, A. Flaus, M.D. Szczelkun, and T. Owen-Hughes Evidence for DNA translocation by the ISWI chromatin-remodeling enzyme Mol Cell Biol 23 2003 1935 1945
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1935-1945
-
-
Whitehouse, I.1
Stockdale, C.2
Flaus, A.3
Szczelkun, M.D.4
Owen-Hughes, T.5
-
12
-
-
0034659247
-
DNA helicases: One small step for PcrA, one giant leap for RecBC?
-
D.B. Wigley DNA helicases: one small step for PcrA, one giant leap for RecBC? Curr Biol 10 2000 R444 R446
-
(2000)
Curr Biol
, vol.10
-
-
Wigley, D.B.1
-
13
-
-
0347539781
-
Histone H2A/H2B dimer exchange by ATP-dependent chromatin remodeling activities
-
M. Bruno, A. Flaus, C. Stockdale, C. Rencurel, H. Ferreira, and T. Owen-Hughes Histone H2A/H2B dimer exchange by ATP-dependent chromatin remodeling activities Mol Cell 12 2003 1599 1606 The authors propose that the loss of histone-DNA contacts near the edge of the nucleosome might make the H2A-H2B dimers susceptible to loss. In keeping with this idea, they show dimer loss and exchange with a variety of remodeler complexes.
-
(2003)
Mol Cell
, vol.12
, pp. 1599-1606
-
-
Bruno, M.1
Flaus, A.2
Stockdale, C.3
Rencurel, C.4
Ferreira, H.5
Owen-Hughes, T.6
-
14
-
-
0033664380
-
Crystal structure of a nucleosome core particle containing the variant histone H2A.Z
-
R.K. Suto, M.J. Clarkson, D.J. Tremethick, and K. Luger Crystal structure of a nucleosome core particle containing the variant histone H2A.Z Nat Struct Biol 7 2000 1121 1124
-
(2000)
Nat Struct Biol
, vol.7
, pp. 1121-1124
-
-
Suto, R.K.1
Clarkson, M.J.2
Tremethick, D.J.3
Luger, K.4
-
15
-
-
6344279816
-
The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres
-
H. Zhang, D.O. Richardson, D.N. Roberts, R. Utley, H. Erdjument-Bromage, P. Tempst, J. Cote, and B.R. Cairns The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres Mol Cell Biol 24 2004 9424 9436 A shared component of the NuA4 and SWR1 complexes, Yaf9, is shown to play a central role in boundary formation. Yaf9 is an ortholog of proteins involved in leukaemias (through MLL/HRX fusions) in higher cells, which suggests that MLL-fusion proteins misregulate target genes because of improper recruitment of chromatin remodeling/modifying factors.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9424-9436
-
-
Zhang, H.1
Richardson, D.O.2
Roberts, D.N.3
Utley, R.4
Erdjument-Bromage, H.5
Tempst, P.6
Cote, J.7
Cairns, B.R.8
-
16
-
-
4544262211
-
Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4
-
N.J. Krogan, K. Baetz, M.C. Keogh, N. Datta, C. Sawa, T.C. Kwok, N.J. Thompson, M.G. Davey, J. Pootoolal, and T.R. Hughes Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4 Proc Natl Acad Sci USA 101 2004 13513 13518
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13513-13518
-
-
Krogan, N.J.1
Baetz, K.2
Keogh, M.C.3
Datta, N.4
Sawa, C.5
Kwok, T.C.6
Thompson, N.J.7
Davey, M.G.8
Pootoolal, J.9
Hughes, T.R.10
-
18
-
-
2942574467
-
Removal of promoter nucleosomes by disassembly rather than sliding in vivo
-
••] provide convincing evidence that nucleosome loss can occur during transcriptional activation. The work involved pioneering a remarkable assay where chromatin mini-circles derived from the PHO5 promoter were isolated and then analyzed for nucleosome content. Here, the authors were able to distinguish loss from sliding/reorganization.
-
(2004)
Mol Cell
, vol.14
, pp. 667-673
-
-
Boeger, H.1
Griesenbeck, J.2
Strattan, J.S.3
Kornberg, R.D.4
-
19
-
-
0038094502
-
Histones are first hyperacetylated and then lose contact with the activated PHO5 promoter
-
H. Reinke, and W. Horz Histones are first hyperacetylated and then lose contact with the activated PHO5 promoter Mol Cell 11 2003 1599 1607 A set of convincing chromatin immunoprecipitation experiments orders the nucleosome-loss phenomenon at the PHO5 promoter during activation, which suggests that acetylation precedes ejection. Also of interest is that appreciable ejection is not observed over the coding region.
-
(2003)
Mol Cell
, vol.11
, pp. 1599-1607
-
-
Reinke, H.1
Horz, W.2
-
20
-
-
2942550662
-
Chromatin disassembly mediated by the histone chaperone Asf1 is essential for transcriptional activation of the yeast PHO5 and PHO8 genes
-
M.W. Adkins, S.R. Howar, and J.K. Tyler Chromatin disassembly mediated by the histone chaperone Asf1 is essential for transcriptional activation of the yeast PHO5 and PHO8 genes Mol Cell 14 2004 657 666 Careful kinetic experiments are coupled with nucleosome occupancy analysis to show that Asf1 mediates the loss of nucleosomes during activation. Nucleosomes reassociate with the promoter during interphase repression showing replication-independent assembly. Also of interest is that Pho4 activator binding does not require nucleosome loss, which is contrary to previous reports.
-
(2004)
Mol Cell
, vol.14
, pp. 657-666
-
-
Adkins, M.W.1
Howar, S.R.2
Tyler, J.K.3
-
22
-
-
8444245244
-
Global nucleosome occupancy in yeast
-
••] provide a genome-wide view of nucleosome occupancy by combining chromatin immunoprecipitation and genomic microarrays. The former study excels in its analysis of loss at particular genes (GAL and heat shock), whereas this investigation excels in its analysis of particular transcription factors (such as Rap1) and combinations of factors that correlate with nucleosome loss.
-
(2004)
Genome Biol
, vol.5
, pp. 62
-
-
Bernstein, B.E.1
Liu, C.L.2
Humphrey, E.L.3
Perlstein, E.O.4
Schreiber, S.L.5
-
23
-
-
0037369952
-
Collaborative competition mechanism for gene activation in vivo
-
J.A. Miller, and J. Widom Collaborative competition mechanism for gene activation in vivo Mol Cell Biol 23 2003 1623 1632 A clever in vivo assay is developed for examining activator occupancy and competition with nucleosomes at a promoter. Activators with recognition sites within a nucleosome repeat length collaborate for binding and compete effectively with nucleosomes. Also of interest is their observation that the Swi-Snf complex appears to function after activator binding.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1623-1632
-
-
Miller, J.A.1
Widom, J.2
-
24
-
-
0033524939
-
Histone octamer transfer by a chromatin-remodeling complex
-
Y. Lorch, M. Zhang, and R.D. Kornberg Histone octamer transfer by a chromatin-remodeling complex Cell 96 1999 389 392
-
(1999)
Cell
, vol.96
, pp. 389-392
-
-
Lorch, Y.1
Zhang, M.2
Kornberg, R.D.3
-
25
-
-
0037108055
-
Histone chaperone ASF1 cooperates with the Brahma chromatin-remodelling machinery
-
Y.M. Moshkin, J.A. Armstrong, R.K. Maeda, J.W. Tamkun, P. Verrijzer, J.A. Kennison, and F. Karch Histone chaperone ASF1 cooperates with the Brahma chromatin-remodelling machinery Genes Dev 16 2002 2621 2626
-
(2002)
Genes Dev
, vol.16
, pp. 2621-2626
-
-
Moshkin, Y.M.1
Armstrong, J.A.2
Maeda, R.K.3
Tamkun, J.W.4
Verrijzer, P.5
Kennison, J.A.6
Karch, F.7
-
27
-
-
2942561969
-
Topography of the ISW2-nucleosome complex: Insights into nucleosome spacing and chromatin remodelling
-
•] provide a careful and rigorous analysis of how ISWI group remodelers engage the nucleosome substrate. Significant similarities emerge (discussed in the text). These studies will be important for all future work on understanding the ISWI mechanism.
-
(2004)
EMBO J
, vol.23
, pp. 2092-2104
-
-
Kagalwala, M.N.1
Glaus, B.J.2
Dang, W.3
Zofall, M.4
Bartholomew, B.5
-
28
-
-
0035137666
-
Critical role for the histone H4 N terminus in nucleosome remodeling by ISWI
-
C.R. Clapier, G. Langst, D.F. Corona, P.B. Becker, and K.P. Nightingale Critical role for the histone H4 N terminus in nucleosome remodeling by ISWI Mol Cell Biol 21 2001 875 883
-
(2001)
Mol Cell Biol
, vol.21
, pp. 875-883
-
-
Clapier, C.R.1
Langst, G.2
Corona, D.F.3
Becker, P.B.4
Nightingale, K.P.5
-
29
-
-
0141922979
-
Crystal structure and functional analysis of a nucleosome recognition module of the remodeling factor ISWI
-
T. Grune, J. Brzeski, A. Eberharter, C.R. Clapier, D.F. Corona, P.B. Becker, and C.W. Muller Crystal structure and functional analysis of a nucleosome recognition module of the remodeling factor ISWI Mol Cell 12 2003 449 460 The structure of two adjacent domains in the ISWI ATPase, SANT and SLIDE, are determined. The two domains have remarkably similar overall structures, strongly resembling the c-myb DNA binding domain; however, whereas the SLIDE domain retains important charged residues for DNA binding, they are altered in the SANT domain, which instead might recognize histone tails.
-
(2003)
Mol Cell
, vol.12
, pp. 449-460
-
-
Grune, T.1
Brzeski, J.2
Eberharter, A.3
Clapier, C.R.4
Corona, D.F.5
Becker, P.B.6
Muller, C.W.7
-
30
-
-
0033603212
-
Nucleosome movement by CHRAC and ISWI without disruption or trans-displacement of the histone octamer
-
G. Langst, E.J. Bonte, D.F. Corona, and P.B. Becker Nucleosome movement by CHRAC and ISWI without disruption or trans-displacement of the histone octamer Cell 97 1999 843 852
-
(1999)
Cell
, vol.97
, pp. 843-852
-
-
Langst, G.1
Bonte, E.J.2
Corona, D.F.3
Becker, P.B.4
-
31
-
-
12144286656
-
Nucleosome binding by the bromodomain and PHD finger of the transcriptional cofactor p300
-
A. Ragvin, H. Valvatne, S. Erdal, V. Arskog, K.R. Tufteland, K. Breen, O.Y. AM, A. Eberharter, T.J. Gibson, and P.B. Becker Nucleosome binding by the bromodomain and PHD finger of the transcriptional cofactor p300 J Mol Biol 337 2004 773 788 The PHD finger is shown to bind the core domain of histones. As this motif is found in so many chromatin proteins, a histone binding function is significant and will inspire further studies.
-
(2004)
J Mol Biol
, vol.337
, pp. 773-788
-
-
Ragvin, A.1
Valvatne, H.2
Erdal, S.3
Arskog, V.4
Tufteland, K.R.5
Breen, K.6
Am, O.Y.7
Eberharter, A.8
Gibson, T.J.9
Becker, P.B.10
-
32
-
-
6344285336
-
Reaction cycle of the yeast Isw2 chromatin remodeling complex
-
D.J. Fitzgerald, C. DeLuca, I. Berger, H. Gaillard, R. Sigrist, K. Schimmele, and T.J. Richmond Reaction cycle of the yeast Isw2 chromatin remodeling complex EMBO J 23 2004 3836 3843 This study uses gel shift and sedimentation analysis to provide the first clear evidence that a conformational change occurs in a remodeler during ATP binding and hydrolysis. How this is used for the mechanism will be of considerable interest.
-
(2004)
EMBO J
, vol.23
, pp. 3836-3843
-
-
Fitzgerald, D.J.1
Deluca, C.2
Berger, I.3
Gaillard, H.4
Sigrist, R.5
Schimmele, K.6
Richmond, T.J.7
-
33
-
-
0037291695
-
Different sensitivities of bromodomain factors 1 and 2 to histone H4 acetylation
-
O. Matangkasombut, and S. Buratowski Different sensitivities of bromodomain factors 1 and 2 to histone H4 acetylation Mol Cell 11 2003 353 363 See annotation 34.
-
(2003)
Mol Cell
, vol.11
, pp. 353-363
-
-
Matangkasombut, O.1
Buratowski, S.2
-
34
-
-
0037291760
-
Bromodomains mediate an acetyl-histone encoded antisilencing function at heterochromatin boundaries
-
•] show that the tandem bromodomain protein Bdf1 binds to the acetylated histone H4 tail. Interestingly, mutations in Bdf1 show repression of telomere-proximal genes, which is similar to what is observed in Htz1 mutants and consistent with a role for Bdf1 in SWR1 complex.
-
(2003)
Mol Cell
, vol.11
, pp. 365-376
-
-
Ladurner, A.G.1
Inouye, C.2
Jain, R.3
Tjian, R.4
-
35
-
-
2942518343
-
Mapping global histone acetylation patterns to gene expression
-
S.K. Kurdistani, S. Tavazoie, and M. Grunstein Mapping global histone acetylation patterns to gene expression Cell 117 2004 721 733 This work clarifies the Bdf1 binding determinant, showing a preference for acetylation at H4K5,8,12 and a lack of acetylation at K16 (see text). Apart from the work on Bdf1 or remodeling, this paper is a landmark in chromatin genomics as it presents the first genome-wide view of histone acetylation with important insights on how acetylation correlates with activation in promoters and coding regions.
-
(2004)
Cell
, vol.117
, pp. 721-733
-
-
Kurdistani, S.K.1
Tavazoie, S.2
Grunstein, M.3
-
36
-
-
2442672951
-
Bromodomain factor 1 (Bdf1) is phosphorylated by protein kinase CK2
-
C. Sawa, E. Nedea, N. Krogan, T. Wada, H. Handa, J. Greenblatt, and S. Buratowski Bromodomain factor 1 (Bdf1) is phosphorylated by protein kinase CK2 Mol Cell Biol 24 2004 4734 4742
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4734-4742
-
-
Sawa, C.1
Nedea, E.2
Krogan, N.3
Wada, T.4
Handa, H.5
Greenblatt, J.6
Buratowski, S.7
-
37
-
-
1942535223
-
Tandem bromodomains in the chromatin remodeler RSC recognize acetylated histone H3 Lys14
-
M. Kasten, H. Szerlong, H. Erdjument-Bromage, P. Tempst, M. Werner, and B.R. Cairns Tandem bromodomains in the chromatin remodeler RSC recognize acetylated histone H3 Lys14 EMBO J 23 2004 1348 1359 This paper provides the first evidence that a bromodomain in a SWI/SNF group remodeler subunit (Rsc4) binds a specific tail modified at a specific position - H3K14. The specificity and genetic interactions are the opposite/complement to the Bdf1/2 group, which prefers H4.
-
(2004)
EMBO J
, vol.23
, pp. 1348-1359
-
-
Kasten, M.1
Szerlong, H.2
Erdjument-Bromage, H.3
Tempst, P.4
Werner, M.5
Cairns, B.R.6
-
38
-
-
0037459376
-
Chromosomal cohesin forms a ring
-
S. Gruber, C.H. Haering, and K. Nasmyth Chromosomal cohesin forms a ring Cell 112 2003 765 777
-
(2003)
Cell
, vol.112
, pp. 765-777
-
-
Gruber, S.1
Haering, C.H.2
Nasmyth, K.3
-
39
-
-
0035230592
-
Splitting the chromosome: Cutting the ties that bind sister chromatids
-
K. Nasmyth, J.M. Peters, and F. Uhlmann Splitting the chromosome: cutting the ties that bind sister chromatids Novartis Found Symp 237 2001 113 133 discussion 133-138, 158-163
-
(2001)
Novartis Found Symp
, vol.237
, pp. 113-133
-
-
Nasmyth, K.1
Peters, J.M.2
Uhlmann, F.3
-
40
-
-
0037194787
-
A chromatin remodelling complex that loads cohesin onto human chromosomes
-
M.A. Hakimi, D.A. Bochar, J.A. Schmiesing, Y. Dong, O.G. Barak, D.W. Speicher, K. Yokomori, and R. Shiekhattar A chromatin remodelling complex that loads cohesin onto human chromosomes Nature 418 2002 994 998
-
(2002)
Nature
, vol.418
, pp. 994-998
-
-
Hakimi, M.A.1
Bochar, D.A.2
Schmiesing, J.A.3
Dong, Y.4
Barak, O.G.5
Speicher, D.W.6
Yokomori, K.7
Shiekhattar, R.8
-
41
-
-
1642499365
-
The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion
-
K.K. Baetz, N.J. Krogan, A. Emili, J. Greenblatt, and P. Hieter The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion Mol Cell Biol 24 2004 1232 1244 An impressive use of genetic array technology and molecular biology is combined to demonstrate a defect in cohesion in rsc mutants resulting in increased rates of chromosome loss.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1232-1244
-
-
Baetz, K.K.1
Krogan, N.J.2
Emili, A.3
Greenblatt, J.4
Hieter, P.5
-
42
-
-
1642266517
-
The RSC nucleosome-remodeling complex is required for cohesin's association with chromosome arms
-
J. Huang, J.M. Hsu, and B.C. Laurent The RSC nucleosome-remodeling complex is required for cohesin's association with chromosome arms Mol Cell 13 2004 739 750 This work excels in its use of chromatin immunoprecipitation from synchronized cells to show that RSC associates with particular sites before the loading of cohesin.
-
(2004)
Mol Cell
, vol.13
, pp. 739-750
-
-
Huang, J.1
Hsu, J.M.2
Laurent, B.C.3
-
43
-
-
0029759928
-
Activator-dependent regulation of transcriptional pausing on nucleosomal templates
-
S.A. Brown, A.N. Imbalzano, and R.E. Kingston Activator-dependent regulation of transcriptional pausing on nucleosomal templates Genes Dev 10 1996 1479 1490
-
(1996)
Genes Dev
, vol.10
, pp. 1479-1490
-
-
Brown, S.A.1
Imbalzano, A.N.2
Kingston, R.E.3
-
44
-
-
0038623298
-
Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation
-
L.L. Corey, C.S. Weirich, I.J. Benjamin, and R.E. Kingston Localized recruitment of a chromatin-remodeling activity by an activator in vivo drives transcriptional elongation Genes Dev 17 2003 1392 1401
-
(2003)
Genes Dev
, vol.17
, pp. 1392-1401
-
-
Corey, L.L.1
Weirich, C.S.2
Benjamin, I.J.3
Kingston, R.E.4
-
45
-
-
0036928142
-
A role for chromatin remodeling in transcriptional termination by RNA polymerase II
-
C. Alen, N.A. Kent, H.S. Jones, J. O'Sullivan, A. Aranda, and N.J. Proudfoot A role for chromatin remodeling in transcriptional termination by RNA polymerase II Mol Cell 10 2002 1441 1452
-
(2002)
Mol Cell
, vol.10
, pp. 1441-1452
-
-
Alen, C.1
Kent, N.A.2
Jones, H.S.3
O'Sullivan, J.4
Aranda, A.5
Proudfoot, N.J.6
-
46
-
-
0038771223
-
Regulated displacement of TBP from the PHO8 promoter in vivo requires Cbf1 and the Isw1 chromatin remodeling complex
-
J.L. Moreau, M. Lee, N. Mahachi, J. Vary, J. Mellor, T. Tsukiyama, and C.R. Goding Regulated displacement of TBP from the PHO8 promoter in vivo requires Cbf1 and the Isw1 chromatin remodeling complex Mol Cell 11 2003 1609 1620 The authors show that the basal level of PHO8 transcription is kept low by the concerted action of Cbf1 and the remodeler ISWI. Cbf1 is the DNA-binding protein that recruits ISWI, whose activity is required for keeping the TATA-binding protein off the promoter.
-
(2003)
Mol Cell
, vol.11
, pp. 1609-1620
-
-
Moreau, J.L.1
Lee, M.2
Mahachi, N.3
Vary, J.4
Mellor, J.5
Tsukiyama, T.6
Goding, C.R.7
-
47
-
-
0345016384
-
Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II
-
A. Morillon, N. Karabetsou, J. O'Sullivan, N. Kent, N. Proudfoot, and J. Mellor Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II Cell 115 2003 425 435 The authors provide the first evidence for a ISWI group remodeler in controlling transcript elongation and termination. The two forms of ISWI complex have different occupancy profiles at target genes: one for the promoter and one for the 3′ end/terminator, which suggests specialization for certain tasks in those locations. Loss of ISWI function has profound effects on RNA polymerase distribution and modification.
-
(2003)
Cell
, vol.115
, pp. 425-435
-
-
Morillon, A.1
Karabetsou, N.2
O'Sullivan, J.3
Kent, N.4
Proudfoot, N.5
Mellor, J.6
-
48
-
-
10944267160
-
Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites
-
J.A. Downs, S. Allard, O. Jobin-Robitaille, A. Javaheri, A. Auger, N. Bouchard, S.J. Kron, S.P. Jackson, and J. Côté Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites Mol Cell 16 2004 979 990 The authors show that a H4 acetyltransferase complex (NuA4) precedes the binding of INO80 complex and SWR1 complex at the break. They also show that the Arp4 component of these complexes binds directly to phospho-H2A.
-
(2004)
Mol Cell
, vol.16
, pp. 979-990
-
-
Downs, J.A.1
Allard, S.2
Jobin-Robitaille, O.3
Javaheri, A.4
Auger, A.5
Bouchard, N.6
Kron, S.J.7
Jackson, S.P.8
Côté, J.9
-
49
-
-
10944224673
-
INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair
-
A.J. Morrison, J. Highland, N.J. Krogan, A. Arbel-Eden, J.F. Greenblatt, J.E. Haber, and X. Shen INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair Cell 119 2004 767 775 INO80 copurifies with phospho-H2A and is rapidly recruited to a double-stranded break.
-
(2004)
Cell
, vol.119
, pp. 767-775
-
-
Morrison, A.J.1
Highland, J.2
Krogan, N.J.3
Arbel-Eden, A.4
Greenblatt, J.F.5
Haber, J.E.6
Shen, X.7
-
50
-
-
10944233962
-
Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair
-
H. van Attikum, O. Fritsch, B. Hohn, and S.M. Gasser Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair Cell 119 2004 777 788 INO80 complex mutants are shown to lack the 3′ single-stranded DNA at the break, suggesting that INO80 removes and/or slides nucleosomes from broken ends to facilitate 5′-3′ DNA resection.
-
(2004)
Cell
, vol.119
, pp. 777-788
-
-
Van Attikum, H.1
Fritsch, O.2
Hohn, B.3
Gasser, S.M.4
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