Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

Nature

Volumn 401, Issue 6754, 1999, Pages 708-712

  Sallusto, Federica ^a   Lenig, Danielle ^a   Förster, Reinhold ^b   Lipp, Martin ^b   Lanzavecchia, Antonio ^a  

^a BASEL INSTITUTE FOR IMMUNOLOGY   (Switzerland)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; IMMUNOLOGICAL MEMORY; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE MIGRATION; LYMPHOCYTE PROLIFERATION; MEMORY CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION;

CELLS, CULTURED; HUMANS; IMMUNOLOGIC MEMORY; INTERFERON TYPE II; L-SELECTIN; LEUKOPOIESIS; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; RECEPTORS, CHEMOKINE; RECEPTORS, LYMPHOCYTE HOMING; T-LYMPHOCYTE SUBSETS;

EID: 0033554726     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/44385     Document Type: Article

References (29)

1. Butcher, E. C. & Picker, L. J. Lymphocyte homing and homeostasis. Science 272, 60-66 (1996).
2. Banchereau, J. & Steinman, R. M. Dendritic cells and the control of immunity. Nature 392, 245-252 (1998).
3. MacLennan, I. C. et al. The changing preference of T and B cells for partners as T-dependent antibody responses develop. Immunol. Rev. 156, 53-66 (1997).
4. Garside, P. et al. Visualization of specific B and T lymphocyte interactions in the lymph node. Science 281, 96-99 (1998).
5. Mackay, C. R. Homing of naive, memory and effector lymphocytes. Curr. Opin. Immunol. 5, 423-427 (1993).
6. Austrup, F. et al. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues. Nature 385, 81-83 (1997).
7. Ahmed, R. & Gray, D. Immunological memory and protective immunity: understanding their relation. Science 272, 54-60 (1996).
8. Zinkernagel, R. M. et al. On immunological memory. Annu. Rev. Immunol. 14, 333-367 (1996).
9. Dutton, R. W., Bradley, L. M. & Swain, S. L. T cell memory. Annu. Rev. Immunol. 16, 201-223 (1998).
10. Gunn, M. D. et al. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc. Natl Acad. Sci USA 95, 258-263 (1998).
11. Campbell, J. J. et al. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science 279, 381-384 (1998).
12. Campbell, J. J. et al. 6-C-kine (SLC), a lymphocyte adhesion-triggering chemokine expressed by high endothelium, is an agonist for the MIP-3β receptor CCR7. J. Cell Biol. 141, 1053-1059 (1998).
13. Mackay, C. R., Marston, W. L. & Dudler, L. Naive and memory T cells show distinct pathways of lymphocyte recirculation. J. Exp. Med. 171, 801-817 (1990).
14. Baggiolini, M. Chemokines and leukocyte traffic. Nature 392, 565-568 (1998).
15. Gunn, M. D. et al. Mice lacing expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J. Exp. Med. 189, 451-460 (1999).
16. Michie, C. A., McLean, A., Alcock, C. & Beverley, P. C. Lifespan of human lymphocyte subsets defined by CD45 isoforms. Nature 360, 264-265 (1992).
17. Baron, J. L., Madri, J. A., Ruddle, N. H., Hashim, G. & Janeway, C. A. Jr Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma. J. Exp. Med. 177, 57-68 (1993).
18. Wu, L. et al. CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro. J. Exp. Med. 185, 1681-1691 (1997).
19. Sallusto, F., Mackay, C. R. & Lanzavecchia, A. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 277, 2005-2007 (1997).
20. Tang, H. L. & Cyster, J. G. Chemokine up-regulation and activated T cell attraction by maturing dendritic cells. Science 284, 819-822 (1999).
21. Sallusto, F., Lenig, D., Mackay, C. R. & Lanzavecchia, A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J. Exp. Med. 187, 875-883 (1998).
22. Grewal, I. S, & Flavell, R. A. CD40 and CD154 in cell-mediated immunity. Annu. Rev. Immunol. 16, 111-135 (1998).
23. Abbas, A. K., Murphy, K. M. & Sher, A. Functional diversity of helper T lymphocytes. Nature 383, 787-793 (1996).
24. Kagi, D., Ledermann, B., Burki, K., Zinkernagel, R. M. & Hengartner, H. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu. Rev. Immunol 14, 207-232 (1996).
25. Casamayor-Palleja, M., Khan, M. & MacLennan, I. C. A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex. J. Exp. Med. 181, 1293-1301 (1995).
26. Hamann, D. et al. Phenotypic and functional separation of memory and effector human CD8+ T cells. J. Exp. Med. 186, 1407-1418 (1997).
27. Sprent, J., Tough, D. F. & Sun, S. Factors controlling the turnover of T memory cells. Immunol. Rev. 156, 79-85 (1997).
28. Tanchot, C. & Rocha, B. The organization of mature T-cell pools. Immunol. Today 19, 575-579 (1998).
29. Weng, N. P., Hathcock, K. S. & Hodes, R. J. Regulation of telomere length and telomerase in T and B cells: a mechanism for maintaining replicative potential. Immunity 9, 151-157 (1998).