Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

Journal of Virology

Volumn 77, Issue 8, 2003, Pages 4911-4927

  Wherry, E John ^a   Blattman, Joseph N ^a,b   Murali Krishna, Kaja ^a,c   Van Der Most, Robbert ^a,d   Ahmed, Rafi ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d Faculty of Veterinary Medicine   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; EPITOPE; GAMMA INTERFERON; INTERLEUKIN 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; CORRELATION ANALYSIS; EXHAUSTION; FEMALE; FUNCTIONAL DISEASE; GENE DELETION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; LYMPHOID TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TARGET CELL; TISSUE DISTRIBUTION; VIRUS INFECTION; VIRUS LOAD;

ANIMALS; BRAIN; CD8-POSITIVE T-LYMPHOCYTES; CHRONIC DISEASE; EPITOPES, T-LYMPHOCYTE; FEMALE; IMMUNODOMINANT EPITOPES; LIVER; LUNG; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; LYMPHOID TISSUE; MICE; MICE, INBRED C57BL; VIRAL LOAD;

EID: 0037383592     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.8.4911-4927.2003     Document Type: Article

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