Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells

Molecular and Cellular Biology

Volumn 24, Issue 20, 2004, Pages 8862-8871

  Jackson, Melany ^a   Krassowska, Anna ^a   Gilbert, Nick ^b   Chevassut, Timothy ^a   Forrester, Lesley ^a   Ansell, John ^a   Ramsahoye, Bernard ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; DNA METHYLTRANSFERASE 1; HISTONE;

ACETYLATION; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL STRUCTURE; CONTROLLED STUDY; DNA METHYLATION; EMBRYO CELL; HEART MUSCLE CELL; HEMATOPOIESIS; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACETYLATION; ANIMALS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA-BINDING PROTEINS; EMBRYO; HEMATOPOIETIC STEM CELLS; HISTONE DEACETYLASES; HISTONES; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; LYSINE; MICE; MICE, KNOCKOUT; MYOCYTES, CARDIAC; OCTAMER TRANSCRIPTION FACTOR-3; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STEM CELLS; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSGENES;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 4744372577     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.20.8862-8871.2004     Document Type: Article

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