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Volumn 207, Issue 3, 2010, Pages 553-564

Dynamic T cell migration program provides resident memory within intestinal epithelium

Author keywords

[No Author keywords available]

Indexed keywords

FINGOLIMOD; IMMUNOGLOBULIN; YELLOW FEVER VACCINE;

EID: 77949506152     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20090858     Document Type: Article
Times cited : (487)

References (46)
  • 1
    • 1642381854 scopus 로고    scopus 로고
    • Immunobiology of mucosal HIV infection and the basis for development of a new generation of mucosal AIDS vaccines
    • doi:10.1016/S1074-7613(04)00053-6
    • Belyakov, I.M., and J.A. Berzofsky. 2004. Immunobiology of mucosal HIV infection and the basis for development of a new generation of mucosal AIDS vaccines. Immunity. 20:247-253. doi:10.1016/S1074-7613(04)00053-6
    • (2004) Immunity , vol.20 , pp. 247-253
    • Belyakov, I.M.1    Berzofsky, J.A.2
  • 2
    • 0032539614 scopus 로고    scopus 로고
    • Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIVvaccinia challenge
    • doi:10.1073/ pnas.95.4.1709
    • Belyakov, I.M., M.A. Derby, J.D. Ahlers, B.L. Kelsall, P. Earl, B. Moss, W. Strober, and J.A. Berzofsky. 1998. Mucosal immunization with HIV-1 peptide vaccine induces mucosal and systemic cytotoxic T lymphocytes and protective immunity in mice against intrarectal recombinant HIVvaccinia challenge. Proc. Natl. Acad. Sci. USA. 95:1709-1714. doi:10.1073/ pnas.95.4.1709
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1709-1714
    • Belyakov, I.M.1    Derby, M.A.2    Ahlers, J.D.3    Kelsall, B.L.4    Earl, P.5    Moss, B.6    Strober, W.7    Berzofsky, J.A.8
  • 3
    • 1642272033 scopus 로고    scopus 로고
    • Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells
    • Belyakov, I.M., S.A. Hammond, J.D. Ahlers, G.M. Glenn, and J.A. Berzofsky. 2004. Transcutaneous immunization induces mucosal CTLs and protective immunity by migration of primed skin dendritic cells. J. Clin. Invest. 113:998-1007.
    • (2004) J. Clin. Invest , vol.113 , pp. 998-1007
    • Belyakov, I.M.1    Hammond, S.A.2    Ahlers, J.D.3    Glenn, G.M.4    Berzofsky, J.A.5
  • 4
    • 24944583626 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics
    • doi:10.1038/ni1240
    • Bromley, S.K., S.Y. Thomas, and A.D. Luster. 2005. Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics. Nat. Immunol. 6:895-901. doi:10.1038/ni1240
    • (2005) Nat. Immunol , vol.6 , pp. 895-901
    • Bromley, S.K.1    Thomas, S.Y.2    Luster, A.D.3
  • 5
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • doi:10.1126/science.272.5258.60
    • Butcher, E.C., and L.J. Picker. 1996. Lymphocyte homing and homeostasis. Science. 272:60-66. doi:10.1126/science.272.5258.60
    • (1996) Science , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, L.J.2
  • 6
    • 0037033376 scopus 로고    scopus 로고
    • + T cells activated in cutaneous or mucosal lymphoid tissues
    • doi:10.1084/jem .20011502
    • + T cells activated in cutaneous or mucosal lymphoid tissues. J. Exp. Med. 195:135-141. doi:10.1084/jem .20011502
    • (2002) J. Exp. Med , vol.195 , pp. 135-141
    • Campbell, D.J.1    Butcher, E.C.2
  • 7
    • 23344451487 scopus 로고    scopus 로고
    • IELs: Enforcing law and order in the court of the intestinal epithelium
    • doi:10.1111/j.0105- 2896.2005.00284.x
    • Cheroutre, H. 2005. IELs: enforcing law and order in the court of the intestinal epithelium. Immunol. Rev. 206:114-131. doi:10.1111/j.0105- 2896.2005.00284.x
    • (2005) Immunol. Rev , vol.206 , pp. 114-131
    • Cheroutre, H.1
  • 9
    • 24944569742 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues
    • doi:10.1038/ni1238
    • Debes, G.F., C.N. Arnold, A.J. Young, S. Krautwald, M. Lipp, J.B. Hay, and E.C. Butcher. 2005. Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues. Nat. Immunol. 6:889-894. doi:10.1038/ni1238
    • (2005) Nat. Immunol , vol.6 , pp. 889-894
    • Debes, G.F.1    Arnold, C.N.2    Young, A.J.3    Krautwald, S.4    Lipp, M.5    Hay, J.B.6    Butcher, E.C.7
  • 10
    • 29644443800 scopus 로고    scopus 로고
    • Memory T cell populations in the lung airways are maintained by continual recruitment
    • Ely, K.H., T. Cookenham, A.D. Roberts, and D.L. Woodland. 2006. Memory T cell populations in the lung airways are maintained by continual recruitment. J. Immunol. 176:537-543.
    • (2006) J. Immunol , vol.176 , pp. 537-543
    • Ely, K.H.1    Cookenham, T.2    Roberts, A.D.3    Woodland, D.L.4
  • 11
    • 0029809510 scopus 로고    scopus 로고
    • Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization
    • doi:10.1084/jem.184.5.1879
    • Gallichan, W.S., and K.L. Rosenthal. 1996. Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization. J. Exp. Med. 184:1879-1890. doi:10.1084/jem.184.5.1879
    • (1996) J. Exp. Med , vol.184 , pp. 1879-1890
    • Gallichan, W.S.1    Rosenthal, K.L.2
  • 12
    • 65249134069 scopus 로고    scopus 로고
    • Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus
    • doi:10.1038/ni.1718
    • Gebhardt, T., L.M. Wakim, L. Eidsmo, P.C. Reading, W.R. Heath, and F.R. Carbone. 2009. Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus. Nat. Immunol. 10:524-530. doi:10.1038/ni.1718
    • (2009) Nat. Immunol , vol.10 , pp. 524-530
    • Gebhardt, T.1    Wakim, L.M.2    Eidsmo, L.3    Reading, P.C.4    Heath, W.R.5    Carbone, F.R.6
  • 13
    • 0032939934 scopus 로고    scopus 로고
    • Haanen, J.B., M. Toebes, T.A. Cordaro, M.C. Wolkers, A.M. Kruisbeek, and T.N. Schumacher. 1999. Systemic T cell expansion during localized viral infection. Eur. J. Immunol. 29:1168-1174. doi:10.1002/(SICI)1521- 4141(199904)29:04〈1168::AID-IMMU1168〉3.0.CO;2-J
    • Haanen, J.B., M. Toebes, T.A. Cordaro, M.C. Wolkers, A.M. Kruisbeek, and T.N. Schumacher. 1999. Systemic T cell expansion during localized viral infection. Eur. J. Immunol. 29:1168-1174. doi:10.1002/(SICI)1521- 4141(199904)29:04〈1168::AID-IMMU1168〉3.0.CO;2-J
  • 14
    • 25844482131 scopus 로고    scopus 로고
    • Perils at mucosal front lines for HIV and SIV and their hosts
    • Haase, A.T. 2005. Perils at mucosal front lines for HIV and SIV and their hosts. Nat. Rev. Immunol. 5:783-792.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 783-792
    • Haase, A.T.1
  • 15
    • 0035162229 scopus 로고    scopus 로고
    • Intraepithelial lymphocytes: Exploring the third way in immunology
    • doi:10.1038/ni1101-997
    • Hayday, A., E. Theodoridis, E. Ramsburg, and J. Shires. 2001. Intraepithelial lymphocytes: exploring the third way in immunology. Nat. Immunol. 2:997-1003. doi:10.1038/ni1101-997
    • (2001) Nat. Immunol , vol.2 , pp. 997-1003
    • Hayday, A.1    Theodoridis, E.2    Ramsburg, E.3    Shires, J.4
  • 17
    • 33846844985 scopus 로고    scopus 로고
    • Generation of gut-homing T cells and their localization to the small intestinal mucosa
    • doi:10.1111/j.1600-065X.2006.00482.x
    • Johansson-Lindbom, B., and W.W. Agace. 2007. Generation of gut-homing T cells and their localization to the small intestinal mucosa. Immunol. Rev. 215:226-242. doi:10.1111/j.1600-065X.2006.00482.x
    • (2007) Immunol. Rev , vol.215 , pp. 226-242
    • Johansson-Lindbom, B.1    Agace, W.W.2
  • 18
    • 0019409703 scopus 로고
    • Immunological memory to Listeria monocytogenes in rodents. IV. Studies on origin and fate of tissue-positioned T memory cells
    • Jungi, T.W., and R. Jungi. 1981. Immunological memory to Listeria monocytogenes in rodents. IV. Studies on origin and fate of tissue-positioned T memory cells. Immunology. 44:789-798.
    • (1981) Immunology , vol.44 , pp. 789-798
    • Jungi, T.W.1    Jungi, R.2
  • 19
    • 0032875664 scopus 로고    scopus 로고
    • Induction and visualization of mucosal memory CD8 T cells following systemic virus infection
    • Kim, S.K., K.S. Schluns, and L. Lefrançois. 1999. Induction and visualization of mucosal memory CD8 T cells following systemic virus infection. J. Immunol. 163:4125-4132.
    • (1999) J. Immunol , vol.163 , pp. 4125-4132
    • Kim, S.K.1    Schluns, K.S.2    Lefrançois, L.3
  • 20
  • 21
    • 0034605043 scopus 로고    scopus 로고
    • Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity
    • doi:10.1084/jem.192.5.761
    • Kunkel, E.J., J.J. Campbell, G. Haraldsen, J. Pan, J. Boisvert, A.I. Roberts, E.C. Ebert, M.A. Vierra, S.B. Goodman, M.C. Genovese, et al. 2000. Lymphocyte CC chemokine receptor 9 and epithelial thymus-expressed chemokine (TECK) expression distinguish the small intestinal immune compartment: Epithelial expression of tissue-specific chemokines as an organizing principle in regional immunity. J. Exp. Med. 192:761-768. doi:10.1084/jem.192.5.761
    • (2000) J. Exp. Med , vol.192 , pp. 761-768
    • Kunkel, E.J.1    Campbell, J.J.2    Haraldsen, G.3    Pan, J.4    Boisvert, J.5    Roberts, A.I.6    Ebert, E.C.7    Vierra, M.A.8    Goodman, S.B.9    Genovese, M.C.10
  • 22
    • 0035498997 scopus 로고    scopus 로고
    • Lymphocytes in the bronchoalveolar space reenter the lung tissue by means of the alveolar epithelium, migrate to regional lymph nodes, and subsequently rejoin the systemic immune system
    • doi:10.1002/ar.1163
    • Lehmann, C., A. Wilkening, D. Leiber, A. Markus, N. Krug, R. Pabst, and T. Tschernig. 2001. Lymphocytes in the bronchoalveolar space reenter the lung tissue by means of the alveolar epithelium, migrate to regional lymph nodes, and subsequently rejoin the systemic immune system. Anat. Rec. 264:229-236. doi:10.1002/ar.1163
    • (2001) Anat. Rec , vol.264 , pp. 229-236
    • Lehmann, C.1    Wilkening, A.2    Leiber, D.3    Markus, A.4    Krug, N.5    Pabst, R.6    Tschernig, T.7
  • 23
    • 33748449719 scopus 로고    scopus 로고
    • Dynamic programming of CD8+ T cell trafficking after live viral immunization
    • doi:10.1016/j.immuni.2006 .06.019
    • Liu, L., R.C. Fuhlbrigge, K. Karibian, T. Tian, and T.S. Kupper. 2006. Dynamic programming of CD8+ T cell trafficking after live viral immunization. Immunity. 25:511-520. doi:10.1016/j.immuni.2006 .06.019
    • (2006) Immunity , vol.25 , pp. 511-520
    • Liu, L.1    Fuhlbrigge, R.C.2    Karibian, K.3    Tian, T.4    Kupper, T.S.5
  • 24
    • 0025343120 scopus 로고
    • Naive and memory T cells show distinct pathways of lymphocyte recirculation
    • doi:10.1084/jem.171.3.801
    • Mackay, C.R., W.L. Marston, and L. Dudler. 1990. Naive and memory T cells show distinct pathways of lymphocyte recirculation. J. Exp. Med. 171:801-817. doi:10.1084/jem.171.3.801
    • (1990) J. Exp. Med , vol.171 , pp. 801-817
    • Mackay, C.R.1    Marston, W.L.2    Dudler, L.3
  • 26
    • 0035865371 scopus 로고    scopus 로고
    • Direct analysis of the dynamics of the intestinal mucosa CD8 T cell response to systemic virus infection
    • Masopust, D., J. Jiang, H. Shen, and L. Lefrançois. 2001a. Direct analysis of the dynamics of the intestinal mucosa CD8 T cell response to systemic virus infection. J. Immunol. 166:2348-2356.
    • (2001) J. Immunol , vol.166 , pp. 2348-2356
    • Masopust, D.1    Jiang, J.2    Shen, H.3    Lefrançois, L.4
  • 27
    • 0035937587 scopus 로고    scopus 로고
    • Preferential localization of effector memory cells in nonlymphoid tissue
    • doi:10.1126/science.1058867
    • Masopust, D., V. Vezys, A.L. Marzo, and L. Lefrançois. 2001b. Preferential localization of effector memory cells in nonlymphoid tissue. Science. 291:2413-2417. doi:10.1126/science.1058867
    • (2001) Science , vol.291 , pp. 2413-2417
    • Masopust, D.1    Vezys, V.2    Marzo, A.L.3    Lefrançois, L.4
  • 29
    • 32044442312 scopus 로고    scopus 로고
    • Cutting edge: Gut microenvironment promotes differentiation of a unique memory CD8 T cell population
    • Masopust, D., V. Vezys, E.J. Wherry, D.L. Barber, and R. Ahmed. 2006. Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population. J. Immunol. 176:2079-2083.
    • (2006) J. Immunol , vol.176 , pp. 2079-2083
    • Masopust, D.1    Vezys, V.2    Wherry, E.J.3    Barber, D.L.4    Ahmed, R.5
  • 32
    • 13244275187 scopus 로고    scopus 로고
    • Reciprocal and dynamic control of CD8 T cell homing by dendritic cells from skin- and gut-associated lymphoid tissues
    • doi:10.1084/jem.20041645
    • Mora, J.R., G. Cheng, D. Picarella, M. Briskin, N. Buchanan, and U.H. von Andrian. 2005. Reciprocal and dynamic control of CD8 T cell homing by dendritic cells from skin- and gut-associated lymphoid tissues. J. Exp. Med. 201:303-316. doi:10.1084/jem.20041645
    • (2005) J. Exp. Med , vol.201 , pp. 303-316
    • Mora, J.R.1    Cheng, G.2    Picarella, D.3    Briskin, M.4    Buchanan, N.5    von Andrian, U.H.6
  • 33
    • 0035495399 scopus 로고    scopus 로고
    • Man the barrier! Strategic defences in the intestinal mucosa
    • doi:10.1038/35095573
    • Nagler-Anderson, C. 2001. Man the barrier! Strategic defences in the intestinal mucosa. Nat. Rev. Immunol. 1:59-67. doi:10.1038/35095573
    • (2001) Nat. Rev. Immunol , vol.1 , pp. 59-67
    • Nagler-Anderson, C.1
  • 34
    • 33644836224 scopus 로고    scopus 로고
    • Mucosal vaccines: The promise and the challenge
    • doi:10.1038/ nri1777
    • Neutra, M.R., and P.A. Kozlowski. 2006. Mucosal vaccines: the promise and the challenge. Nat. Rev. Immunol. 6:148-158. doi:10.1038/ nri1777
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 148-158
    • Neutra, M.R.1    Kozlowski, P.A.2
  • 35
    • 0030821281 scopus 로고    scopus 로고
    • Treatment with either anti-CD4 or anti-CD8 monoclonal antibodies blocks alphabeta T cell-mediated rejection of intestinal allografts in mice
    • doi:10.1097/00007890-199710150-00004
    • Newell, K.A., G. He, J. Hart, and J.R. Thistlethwaite Jr. 1997. Treatment with either anti-CD4 or anti-CD8 monoclonal antibodies blocks alphabeta T cell-mediated rejection of intestinal allografts in mice. Transplantation. 64:959-965. doi:10.1097/00007890-199710150-00004
    • (1997) Transplantation , vol.64 , pp. 959-965
    • Newell, K.A.1    He, G.2    Hart, J.3    Thistlethwaite Jr., J.R.4
  • 36
    • 0029554250 scopus 로고
    • Immune cell traffic from blood through the normal human skin to lymphatics
    • doi:10.1016/0738-081X(95)00087-V
    • Olszewski, W.L., I. Grzelak, A. Ziolkowska, and A. Engeset. 1995. Immune cell traffic from blood through the normal human skin to lymphatics. Clin. Dermatol. 13:473-483. doi:10.1016/0738-081X(95)00087-V
    • (1995) Clin. Dermatol , vol.13 , pp. 473-483
    • Olszewski, W.L.1    Grzelak, I.2    Ziolkowska, A.3    Engeset, A.4
  • 37
    • 1342300522 scopus 로고    scopus 로고
    • Chemokine receptor CCR9 contributes to the localization of plasma cells to the small intestine
    • doi:10.1084/jem.20030996
    • Pabst, O., L. Ohl, M. Wendland, M.A. Wurbel, E. Kremmer, B. Malissen, and R. Förster. 2004. Chemokine receptor CCR9 contributes to the localization of plasma cells to the small intestine. J. Exp. Med. 199:411-416. doi:10.1084/jem.20030996
    • (2004) J. Exp. Med , vol.199 , pp. 411-416
    • Pabst, O.1    Ohl, L.2    Wendland, M.3    Wurbel, M.A.4    Kremmer, E.5    Malissen, B.6    Förster, R.7
  • 39
    • 0035282433 scopus 로고    scopus 로고
    • Visualizing the generation of memory CD4 T cells in the whole body
    • doi:10.1038/35065111
    • Reinhardt, R.L., A. Khoruts, R. Merica, T. Zell, and M.K. Jenkins. 2001. Visualizing the generation of memory CD4 T cells in the whole body. Nature. 410:101-105. doi:10.1038/35065111
    • (2001) Nature , vol.410 , pp. 101-105
    • Reinhardt, R.L.1    Khoruts, A.2    Merica, R.3    Zell, T.4    Jenkins, M.K.5
  • 40
    • 2142730100 scopus 로고    scopus 로고
    • Central memory and effector memory T cell subsets: Function, generation, and maintenance
    • doi:10.1146/annurev.immunol .22.012703.104702
    • Sallusto, F., J. Geginat, and A. Lanzavecchia. 2004. Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu. Rev. Immunol. 22:745-763. doi:10.1146/annurev.immunol .22.012703.104702
    • (2004) Annu. Rev. Immunol , vol.22 , pp. 745-763
    • Sallusto, F.1    Geginat, J.2    Lanzavecchia, A.3
  • 41
    • 36248956701 scopus 로고    scopus 로고
    • Finding a way out: Lymphocyte egress from lymphoid organs
    • doi:10 .1038/ni1545
    • Schwab, S.R., and J.G. Cyster. 2007. Finding a way out: lymphocyte egress from lymphoid organs. Nat. Immunol. 8:1295-1301. doi:10 .1038/ni1545
    • (2007) Nat. Immunol , vol.8 , pp. 1295-1301
    • Schwab, S.R.1    Cyster, J.G.2
  • 42
    • 0036099957 scopus 로고    scopus 로고
    • Stagg, A.J., M.A. Kamm, and S.C. Knight. 2002. Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin. Eur. J. Immunol. 32:1445-1454. doi:10.1002/1521-4141(200205)32:5〈1445::AID-IMMU1445〉 3.0.CO;2-E
    • Stagg, A.J., M.A. Kamm, and S.C. Knight. 2002. Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin. Eur. J. Immunol. 32:1445-1454. doi:10.1002/1521-4141(200205)32:5〈1445::AID-IMMU1445〉 3.0.CO;2-E
  • 43
    • 0036827820 scopus 로고    scopus 로고
    • Both mucosal and systemic routes of immunization with the live, attenuated NYVAC/simian immunodeficiency virus SIV(gpe) recombinant vaccine result in gag-specific CD8(+) T-cell responses in mucosal tissues of macaques
    • doi:10.1128/JVI.76.22 .11659-11676.2002
    • Stevceva, L., X. Alvarez, A.A. Lackner, E. Tryniszewska, B. Kelsall, J. Nacsa, J. Tartaglia, W. Strober, and G. Franchini. 2002. Both mucosal and systemic routes of immunization with the live, attenuated NYVAC/simian immunodeficiency virus SIV(gpe) recombinant vaccine result in gag-specific CD8(+) T-cell responses in mucosal tissues of macaques. J. Virol. 76:11659-11676. doi:10.1128/JVI.76.22 .11659-11676.2002
    • (2002) J. Virol , vol.76 , pp. 11659-11676
    • Stevceva, L.1    Alvarez, X.2    Lackner, A.A.3    Tryniszewska, E.4    Kelsall, B.5    Nacsa, J.6    Tartaglia, J.7    Strober, W.8    Franchini, G.9
  • 44
    • 0034609968 scopus 로고    scopus 로고
    • T-cell function and migration. Two sides of the same coin
    • doi:10.1056/NEJM200010053431407
    • von Andrian, U.H., and C.R. Mackay. 2000. T-cell function and migration. Two sides of the same coin. N. Engl. J. Med. 343:1020-1034. doi:10.1056/NEJM200010053431407
    • (2000) N. Engl. J. Med , vol.343 , pp. 1020-1034
    • von Andrian, U.H.1    Mackay, C.R.2
  • 45
    • 33750024198 scopus 로고    scopus 로고
    • Donor lymphoid organs are a major site of alloreactive T-cell priming following intestinal transplantation
    • doi:10.1111/j.1600-6143.2006.01516.x
    • Wang, J., Y. Dong, J.Z. Sun, R.T. Taylor, C. Guo, M.L. Alegre, I.R. Williams, and K.A. Newell. 2006. Donor lymphoid organs are a major site of alloreactive T-cell priming following intestinal transplantation. Am. J. Transplant. 6:2563-2571. doi:10.1111/j.1600-6143.2006.01516.x
    • (2006) Am. J. Transplant , vol.6 , pp. 2563-2571
    • Wang, J.1    Dong, Y.2    Sun, J.Z.3    Taylor, R.T.4    Guo, C.5    Alegre, M.L.6    Williams, I.R.7    Newell, K.A.8
  • 46
    • 0033231492 scopus 로고    scopus 로고
    • Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis
    • doi:10.1084/jem.190.9.1241
    • Zabel, B.A., W.W. Agace, J.J. Campbell, H.M. Heath, D. Parent, A.I. Roberts, E.C. Ebert, N. Kassam, S. Qin, M. Zovko, et al. 1999. Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis. J. Exp. Med. 190:1241-1256. doi:10.1084/jem.190.9.1241
    • (1999) J. Exp. Med , vol.190 , pp. 1241-1256
    • Zabel, B.A.1    Agace, W.W.2    Campbell, J.J.3    Heath, H.M.4    Parent, D.5    Roberts, A.I.6    Ebert, E.C.7    Kassam, N.8    Qin, S.9    Zovko, M.10


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