-
1
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
239-57
-
Kerr J F, Wyllie A H and Currie A R 1972 Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics Br. J. Cancer 26 239-57
-
(1972)
Br. J. Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
2
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
71-94
-
Brenner S 1974 The genetics of Caenorhabditis elegans Genetics 77 71-94
-
(1974)
Genetics
, vol.77
, pp. 71-94
-
-
Brenner, S.1
-
3
-
-
0017618537
-
Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
-
110-56
-
Sulston J E and Horvitz H R 1977 Post-embryonic cell lineages of the nematode, Caenorhabditis elegans Dev. Biol. 56 110-56
-
(1977)
Dev. Biol.
, vol.56
, pp. 110-156
-
-
Sulston, J.E.1
Horvitz, H.R.2
-
5
-
-
0020557883
-
Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans
-
1277-9
-
Hedgecock E M, Sulston J E and Thomson J N 1983 Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans Science 220 1277-9
-
(1983)
Science
, vol.220
, pp. 1277-1279
-
-
Hedgecock, E.M.1
Sulston, J.E.2
Thomson, J.N.3
-
6
-
-
9544246860
-
Mitochondrial permeability transition is a central coordinating event of apoptosis
-
1155-60
-
Marchetti P, Castedo M, Susin S A, Zamzami N, Hirsch T, Macho A, Haeffner A, Hirsch F, Geuskens M and Kroemer G 1996 Mitochondrial permeability transition is a central coordinating event of apoptosis J. Exp. Med. 184 1155-60
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1155-1160
-
-
Marchetti, P.1
Castedo, M.2
Susin, S.A.3
Zamzami, N.4
Hirsch, T.5
MacHo, A.6
Haeffner, A.7
Hirsch, F.8
Geuskens, M.9
Kroemer, G.10
-
7
-
-
84871282941
-
Cell death in parasitic protozoa: Regulated or incidental?
-
58-66
-
Proto W R, Coombs G H and Mottram J C 2013 Cell death in parasitic protozoa: regulated or incidental? Nat. Rev. Microbiol. 11 58-66
-
(2013)
Nat. Rev. Microbiol.
, vol.11
, pp. 58-66
-
-
Proto, W.R.1
Coombs, G.H.2
Mottram, J.C.3
-
9
-
-
0036347029
-
A form of cell death with some features resembling apoptosis in the amitochondrial unicellular organism trichomonas vaginalis
-
32-9
-
Chose O, Noël C, Gerbod D, Brenner C, Viscogliosi E and Roseto A 2002 A form of cell death with some features resembling apoptosis in the amitochondrial unicellular organism trichomonas vaginalis Exp. Cell. Res. 276 32-9
-
(2002)
Exp. Cell. Res.
, vol.276
, pp. 32-39
-
-
Chose, O.1
Noël, C.2
Gerbod, D.3
Brenner, C.4
Viscogliosi, E.5
Roseto, A.6
-
10
-
-
0344430169
-
Programmed cell death in parasitic protozoans that lack mitochondria
-
559-64
-
Chose O, Sarde C O, Gerbod D, Viscogliosi E and Roseto A 2003 Programmed cell death in parasitic protozoans that lack mitochondria Trends Parasitol. 19 559-64
-
(2003)
Trends Parasitol.
, vol.19
, pp. 559-564
-
-
Chose, O.1
Sarde, C.O.2
Gerbod, D.3
Viscogliosi, E.4
Roseto, A.5
-
11
-
-
0029893702
-
The origin of programmed cell death
-
1278-9
-
Ameisen J C 1996 The origin of programmed cell death Science 272 1278-9
-
(1996)
Science
, vol.272
, pp. 1278-1279
-
-
Ameisen, J.C.1
-
12
-
-
84885370080
-
Cell death proteins: An evolutionary role in cellular adaptation before the advent of apoptosis
-
974-83
-
Dick S A and Megeney L A 2013 Cell death proteins: an evolutionary role in cellular adaptation before the advent of apoptosis Bioessays 35 974-83
-
(2013)
Bioessays
, vol.35
, pp. 974-983
-
-
Dick, S.A.1
Megeney, L.A.2
-
13
-
-
0030605023
-
Mitochondria and programmed cell death: Back to the future
-
7-13
-
Petit P, Susin S, Zamzami N, Mignotte B and Kroemer G 1996 Mitochondria and programmed cell death: back to the future FEBS Lett. 396 7-13
-
(1996)
FEBS Lett.
, vol.396
, pp. 7-13
-
-
Petit, P.1
Susin, S.2
Zamzami, N.3
Mignotte, B.4
Kroemer, G.5
-
14
-
-
14044251695
-
Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution
-
443-56
-
Kroemer G 1997 Mitochondrial implication in apoptosis. towards an endosymbiont hypothesis of apoptosis evolution Cell Death Differ. 4 443-56
-
(1997)
Cell Death Differ.
, vol.4
, pp. 443-456
-
-
Kroemer, G.1
-
15
-
-
84890464366
-
Bacterial programmed cell death: Making sense of a paradox
-
63-9
-
Bayles K W 2014 Bacterial programmed cell death: making sense of a paradox Nat. Rev. Microbiol. 12 63-9
-
(2014)
Nat. Rev. Microbiol.
, vol.12
, pp. 63-69
-
-
Bayles, K.W.1
-
16
-
-
5244224827
-
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death
-
335-41
-
Muchmore S W et al 1996 X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death Nature 381 335-41
-
(1996)
Nature
, vol.381
, pp. 335-341
-
-
Muchmore, S.W.1
-
17
-
-
0031008397
-
Channel formation by antiapoptotic protein Bcl-2
-
5113-8
-
Schendel S L, Xie Z, Montal M O, Matsuyama S, Montal M and Reed J C 1997 Channel formation by antiapoptotic protein Bcl-2 Proc. Natl Acad. Sci. USA 94 5113-8
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 5113-5118
-
-
Schendel, S.L.1
Xie, Z.2
Montal, M.O.3
Matsuyama, S.4
Montal, M.5
Reed, J.C.6
-
18
-
-
0031993255
-
Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast
-
337-46
-
Xu Q and Reed J C 1998 Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast Mol. Cell 1 337-46
-
(1998)
Mol. Cell
, vol.1
, pp. 337-346
-
-
Xu, Q.1
Reed, J.C.2
-
19
-
-
3242806002
-
BAX Inhibitor-1, an ancient cell death suppressor in animals and plants with prokaryotic relatives
-
299-307
-
Hückelhoven R 2004 BAX Inhibitor-1, an ancient cell death suppressor in animals and plants with prokaryotic relatives Apoptosis 9 299-307
-
(2004)
Apoptosis
, vol.9
, pp. 299-307
-
-
Hückelhoven, R.1
-
20
-
-
79960216863
-
Bax inhibitor-1: A highly conserved endoplasmic reticulum-resident cell death suppressor
-
1271-8
-
Ishikawa T, Watanabe N, Nagano M, Kawai-Yamada M and Lam E 2011 Bax inhibitor-1: a highly conserved endoplasmic reticulum-resident cell death suppressor Cell Death Differ. 18 1271-8
-
(2011)
Cell Death Differ.
, vol.18
, pp. 1271-1278
-
-
Ishikawa, T.1
Watanabe, N.2
Nagano, M.3
Kawai-Yamada, M.4
Lam, E.5
-
21
-
-
0031239745
-
Origin of eukaryotic programmed cell death: A consequence of aerobic metabolism?
-
827-32
-
Frade J M and Michaelidis T M 1997 Origin of eukaryotic programmed cell death: a consequence of aerobic metabolism? Bioessays 19 827-32
-
(1997)
Bioessays
, vol.19
, pp. 827-832
-
-
Frade, J.M.1
Michaelidis, T.M.2
-
22
-
-
0035895540
-
Apoptotic molecular machinery: Vastly increased complexity in vertebrates revealed by genome comparisons
-
1279-84
-
Aravind L, Dixit V M and Koonin E V 2001 Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons Science 291 1279-84
-
(2001)
Science
, vol.291
, pp. 1279-1284
-
-
Aravind, L.1
Dixit, V.M.2
Koonin, E.V.3
-
23
-
-
0036316720
-
Origin and evolution of eukaryotic apoptosis: The bacterial connection
-
394-404
-
Koonin E V and Aravind L 2002 Origin and evolution of eukaryotic apoptosis: the bacterial connection Cell Death Differ. 9 394-404
-
(2002)
Cell Death Differ.
, vol.9
, pp. 394-404
-
-
Koonin, E.V.1
Aravind, L.2
-
24
-
-
0037427410
-
Scission, spores, and apoptosis: A proposal for the evolutionary origin of mitochondria in cell death induction
-
481-6
-
Frank S, Robert E G and Youle R J 2003 Scission, spores, and apoptosis: a proposal for the evolutionary origin of mitochondria in cell death induction Biochem. Biophys. Res. Commun. 304 481-6
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 481-486
-
-
Frank, S.1
Robert, E.G.2
Youle, R.J.3
-
25
-
-
0027525104
-
The C. Elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 β-converting enzyme
-
641-52
-
Yuan J, Shaham S, Ledoux S, Ellis H M and Horvitz H R 1993 The C. Elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 β-converting enzyme Cell 75 641-52
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shaham, S.2
Ledoux, S.3
Ellis, H.M.4
Horvitz, H.R.5
-
26
-
-
0028288277
-
C. Elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
-
665-76
-
Hengartner M O and Horvitz H R 1994 C. Elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2 Cell 76 665-76
-
(1994)
Cell
, vol.76
, pp. 665-676
-
-
Hengartner, M.O.1
Horvitz, H.R.2
-
27
-
-
0030745646
-
Apaf-1, a human protein homologous to C. Elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
405-13
-
Zou H, Henzel W J, Liu X, Lutschg A and Wang X 1997 Apaf-1, a human protein homologous to C. Elegans CED-4, participates in cytochrome c-dependent activation of caspase-3 Cell 90 405-13
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
28
-
-
0031731989
-
Genetics of programmed cell death in C. Elegans: Past, present and future
-
410-6
-
Metzstein M M, Stanfield G M and Horvitz H R 1998 Genetics of programmed cell death in C. Elegans: past, present and future Trends Genet. 14 410-6
-
(1998)
Trends Genet.
, vol.14
, pp. 410-416
-
-
Metzstein, M.M.1
Stanfield, G.M.2
Horvitz, H.R.3
-
29
-
-
0032524885
-
The C. Elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9
-
519-29
-
Conradt B and Horvitz H R 1998 The C. Elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9 Cell 93 519-29
-
(1998)
Cell
, vol.93
, pp. 519-529
-
-
Conradt, B.1
Horvitz, H.R.2
-
30
-
-
0020808726
-
Egg-laying defective mutants of the nematode Caenorhabditis elegans
-
619-47
-
Trent C, Tsuing N and Horvitz H R 1983 Egg-laying defective mutants of the nematode Caenorhabditis elegans Genetics 104 619-47
-
(1983)
Genetics
, vol.104
, pp. 619-647
-
-
Trent, C.1
Tsuing, N.2
Horvitz, H.R.3
-
31
-
-
26844485563
-
Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans
-
831-7
-
Yan N et al 2005 Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans Nature 437 831-7
-
(2005)
Nature
, vol.437
, pp. 831-837
-
-
Yan, N.1
-
32
-
-
0034712042
-
Translocation of C. Elegans CED-4 to nuclear membranes during programmed cell death
-
1485-9
-
Chen F, Hersh B M, Conradt B, Zhou Z, Riemer D, Gruenbaum Y and Horvitz H R 2000 Translocation of C. Elegans CED-4 to nuclear membranes during programmed cell death Science 287 1485-9
-
(2000)
Science
, vol.287
, pp. 1485-1489
-
-
Chen, F.1
Hersh, B.M.2
Conradt, B.3
Zhou, Z.4
Riemer, D.5
Gruenbaum, Y.6
Horvitz, H.R.7
-
33
-
-
77951881456
-
Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4
-
446-57
-
Qi S et al 2010 Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4 Cell 141 446-57
-
(2010)
Cell
, vol.141
, pp. 446-457
-
-
Qi, S.1
-
34
-
-
0033596980
-
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
-
11549-56
-
Zou H, Li Y, Liu X and Wang X 1999 An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9 J. Biol. Chem. 274 11549-56
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11549-11556
-
-
Zou, H.1
Li, Y.2
Liu, X.3
Wang, X.4
-
35
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
207-11
-
Soengas M S et al 2001 Inactivation of the apoptosis effector Apaf-1 in malignant melanoma Nature 409 207-11
-
(2001)
Nature
, vol.409
, pp. 207-211
-
-
Soengas, M.S.1
-
36
-
-
0036187036
-
Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
-
423-32
-
Acehan D, Jiang X, Morgan D G, Heuser J E, Wang X and Akey C W 2002 Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation Mol. Cell 9 423-32
-
(2002)
Mol. Cell
, vol.9
, pp. 423-432
-
-
Acehan, D.1
Jiang, X.2
Morgan, D.G.3
Heuser, J.E.4
Wang, X.5
Akey, C.W.6
-
37
-
-
84876173871
-
The first suicides: A legacy inherited by parasitic protozoans from prokaryote ancestors
-
Taylor-Brown E and Hurd H 2013 The first suicides: a legacy inherited by parasitic protozoans from prokaryote ancestors Parasites Vectors 6 108
-
(2013)
Parasites Vectors
, vol.6
, pp. 108
-
-
Taylor-Brown, E.1
Hurd, H.2
-
38
-
-
42449123761
-
Expansion and evolution of cell death programmes
-
378-90
-
Degterev A and Yuan J 2008 Expansion and evolution of cell death programmes Nat. Rev. Mol. Cell Biol. 9 378-90
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 378-390
-
-
Degterev, A.1
Yuan, J.2
-
39
-
-
84894295410
-
An alternative root for the eukaryote tree of life
-
465-70
-
He D, Fiz-Palacios O, Fu C J, Fehling J, Tsai C C and Baldauf S L 2014 An alternative root for the eukaryote tree of life Curr. Biol. 24 465-70
-
(2014)
Curr. Biol.
, vol.24
, pp. 465-470
-
-
He, D.1
Fiz-Palacios, O.2
Fu, C.J.3
Fehling, J.4
Tsai, C.C.5
Baldauf, S.L.6
-
40
-
-
79953111659
-
Evolution of apoptosis-like programmed cell death in unicellular protozoan parasites
-
Kaczanowski S, Sajid M and Reece S E 2011 Evolution of apoptosis-like programmed cell death in unicellular protozoan parasites Parasites Vectors 4 44
-
(2011)
Parasites Vectors
, vol.4
, pp. 44
-
-
Kaczanowski, S.1
Sajid, M.2
Reece, S.E.3
-
41
-
-
84867310470
-
The revised classification of eukaryotes
-
429-93
-
Adl S M et al 2012 The revised classification of eukaryotes J. Eukaryotic Microbiol. 59 429-93
-
(2012)
J. Eukaryotic Microbiol.
, vol.59
, pp. 429-493
-
-
Adl, S.M.1
-
42
-
-
0037022594
-
Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome
-
2800-5
-
Lange C and Hunte C 2002 Crystal structure of the yeast cytochrome bc1 complex with its bound substrate cytochrome c Proc. Natl Acad. Sci. USA 99 2800-5
-
(2002)
C Proc. Natl Acad. Sci. USA
, vol.99
, pp. 2800-2805
-
-
Lange, C.1
Hunte, C.2
-
43
-
-
27444438569
-
Hyperosmotic stress induces metacaspase- and mitochondria-dependent apoptosis in Saccharomyces cerevisiae
-
824-34
-
Silva R D, Sotoca R, Johansson B, Ludovico P, Sansonetty F, Silva M T, Peinado J M and Côrte-Real M 2005 Hyperosmotic stress induces metacaspase- and mitochondria-dependent apoptosis in Saccharomyces cerevisiae Mol. Microbiol. 58 824-34
-
(2005)
Mol. Microbiol.
, vol.58
, pp. 824-834
-
-
Silva, R.D.1
Sotoca, R.2
Johansson, B.3
Ludovico, P.4
Sansonetty, F.5
Silva, M.T.6
Peinado, J.M.7
Côrte-Real, M.8
-
44
-
-
0031037897
-
The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
-
1132-6
-
Kluck R, Bossy-Wetzel E, Green D and Newmeyer D 1997 The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis Science 275 1132-6
-
(1997)
Science
, vol.275
, pp. 1132-1136
-
-
Kluck, R.1
Bossy-Wetzel, E.2
Green, D.3
Newmeyer, D.4
-
45
-
-
69149109036
-
AIF: Not just an apoptosis-inducing factor
-
2-11
-
Joza N, Pospisilik J A, Hangen E, Hanada T, Modjtahedi N, Penninger J M and Kroemer G 2009 AIF: not just an apoptosis-inducing factor Ann. NY Acad. Sci. 1171 2-11
-
(2009)
Ann. NY Acad. Sci.
, vol.1171
, pp. 2-11
-
-
Joza, N.1
Pospisilik, J.A.2
Hangen, E.3
Hanada, T.4
Modjtahedi, N.5
Penninger, J.M.6
Kroemer, G.7
-
46
-
-
21244436773
-
Molecular cloning and characterization of a human AIF-like gene with ability to induce apoptosis
-
19673-81
-
Xie Q, Lin T, Zhang Y, Zheng J and Bonanno J A 2005 Molecular cloning and characterization of a human AIF-like gene with ability to induce apoptosis J. Biol. Chem. 280 19673-81
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 19673-19681
-
-
Xie, Q.1
Lin, T.2
Zhang, Y.3
Zheng, J.4
Bonanno, J.A.5
-
47
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
441-6
-
Susin S A et al 1999 Molecular characterization of mitochondrial apoptosis-inducing factor Nature 397 441-6
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
-
48
-
-
0037067694
-
AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis
-
25617-23
-
Wu M, Xu L G, Li X, Zhai Z and Shu H B 2002 AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis J. Biol. Chem. 277 25617-23
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25617-25623
-
-
Wu, M.1
Xu, L.G.2
Li, X.3
Zhai, Z.4
Shu, H.B.5
-
49
-
-
4644246439
-
An AIF orthologue regulates apoptosis in yeast
-
969-74
-
Wissing S et al 2004 An AIF orthologue regulates apoptosis in yeast J. Cell Biol. 166 969-74
-
(2004)
J. Cell Biol.
, vol.166
, pp. 969-974
-
-
Wissing, S.1
-
50
-
-
0035166350
-
On the evolutionary conservation of the cell death pathway: Mitochondrial release of an apoptosis-inducing factor during Dictyostelium discoideum cell death
-
3016-30
-
Arnoult D et al 2001 On the evolutionary conservation of the cell death pathway: mitochondrial release of an apoptosis-inducing factor during Dictyostelium discoideum cell death Mol. Biol. Cell. 12 3016-30
-
(2001)
Mol. Biol. Cell.
, vol.12
, pp. 3016-3030
-
-
Arnoult, D.1
-
51
-
-
77649165911
-
Role of apoptosis-inducing factor (AIF) in programmed nuclear death during conjugation in Tetrahymena thermophila
-
Akematsu T and Endoh H 2010 Role of apoptosis-inducing factor (AIF) in programmed nuclear death during conjugation in Tetrahymena thermophila BMC Cell Biol. 11 13
-
(2010)
BMC Cell Biol.
, vol.11
, pp. 13
-
-
Akematsu, T.1
Endoh, H.2
-
52
-
-
0037205746
-
A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF)
-
163-71
-
Ohiro Y et al 2002 A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF) FEBS Lett. 524 163-71
-
(2002)
FEBS Lett.
, vol.524
, pp. 163-171
-
-
Ohiro, Y.1
-
53
-
-
13044305983
-
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia
-
5752-7
-
Krajewski S et al 1999 Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia Proc. Natl Acad. Sci. USA 96 5752-7
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 5752-5757
-
-
Krajewski, S.1
-
54
-
-
0034194338
-
Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis
-
603-12
-
Mancini M, Machamer C E, Roy S, Nicholson D W, Thornberry N A, Casciola-Rosen L A and Rosen A 2000 Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis J. Cell Biol. 149 603-12
-
(2000)
J. Cell Biol.
, vol.149
, pp. 603-612
-
-
Mancini, M.1
MacHamer, C.E.2
Roy, S.3
Nicholson, D.W.4
Thornberry, N.A.5
Casciola-Rosen, L.A.6
Rosen, A.7
-
55
-
-
0034785591
-
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
-
613-21
-
Suzuki Y, Imai Y, Nakayama H, Takahashi K, Takio K and Takahashi R 2001 A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death Mol. Cell. 8 613-21
-
(2001)
Mol. Cell.
, vol.8
, pp. 613-621
-
-
Suzuki, Y.1
Imai, Y.2
Nakayama, H.3
Takahashi, K.4
Takio, K.5
Takahashi, R.6
-
56
-
-
80053369271
-
Nma111p, the pro-apoptotic HtrA-like nuclear serine protease in Saccharomyces cerevisiae: A short survey
-
1499-501
-
Fahrenkrog B 2011 Nma111p, the pro-apoptotic HtrA-like nuclear serine protease in Saccharomyces cerevisiae: a short survey Biochem. Soc. Trans. 39 1499-501
-
(2011)
Biochem. Soc. Trans.
, vol.39
, pp. 1499-1501
-
-
Fahrenkrog, B.1
-
57
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
95-9
-
Li L Y, Luo X and Wang X 2001 Endonuclease G is an apoptotic DNase when released from mitochondria Nature 412 95-9
-
(2001)
Nature
, vol.412
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
58
-
-
84896730602
-
A novel mitochondrial nuclease-associated protein: A major executor of the programmed nuclear death in Tetrahymena thermophila
-
97-109
-
Osada E, Akematsu T, Asano T and Endoh H 2014 A novel mitochondrial nuclease-associated protein: a major executor of the programmed nuclear death in Tetrahymena thermophila Biol. Cell 106 97-109
-
(2014)
Biol. Cell
, vol.106
, pp. 97-109
-
-
Osada, E.1
Akematsu, T.2
Asano, T.3
Endoh, H.4
-
59
-
-
0034636713
-
The C. Elegans apoptotic nuclease NUC-1 is related in sequence and activity to mammalian DNase II
-
147-54
-
Lyon C, Evans C, Bill B, Otsuka A and Aguilera R 2000 The C. Elegans apoptotic nuclease NUC-1 is related in sequence and activity to mammalian DNase II Gene 252 147-54
-
(2000)
Gene
, vol.252
, pp. 147-154
-
-
Lyon, C.1
Evans, C.2
Bill, B.3
Otsuka, A.4
Aguilera, R.5
-
60
-
-
0344009629
-
DNase II genes, enzymes and function
-
1-15
-
Evans C J and Aguilera R J 2003 DNase II genes, enzymes and function Gene 322 1-15
-
(2003)
Gene
, vol.322
, pp. 1-15
-
-
Evans, C.J.1
Aguilera, R.J.2
-
61
-
-
2342620831
-
Metacaspase-dependent programmed cell death is essential for plant embryogenesis
-
R339-40
-
Suarez M F, Filonova L H, Smertenko A, Savenkov E I, Clapham D H, von Arnold S, Zhivotovsky B and Bozhkov P V 2004 Metacaspase-dependent programmed cell death is essential for plant embryogenesis Curr. Biol. 14 R339-40
-
(2004)
Curr. Biol.
, vol.14
, pp. R339-R340
-
-
Suarez, M.F.1
Filonova, L.H.2
Smertenko, A.3
Savenkov, E.I.4
Clapham, D.H.5
Von Arnold, S.6
Zhivotovsky, B.7
Bozhkov, P.V.8
-
62
-
-
18344374857
-
A caspase-related protease regulates apoptosis in yeast
-
911-7
-
Madeo F et al 2002 A caspase-related protease regulates apoptosis in yeast Mol. Cell 9 911-7
-
(2002)
Mol. Cell
, vol.9
, pp. 911-917
-
-
Madeo, F.1
-
63
-
-
70449529844
-
Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome
-
1347-54
-
Sundström J et al 2009 Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome Nat. Cell Biol. 11 1347-54
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1347-1354
-
-
Sundström, J.1
-
64
-
-
84877873912
-
The non-death role of metacaspase proteases
-
Shrestha A and Megeney L A 2012 The non-death role of metacaspase proteases Frontiers Oncol. 2 78
-
(2012)
Frontiers Oncol.
, vol.2
, pp. 78
-
-
Shrestha, A.1
Megeney, L.A.2
-
65
-
-
84873411033
-
Caspase signalling in the absence of apoptosis drives Jnk-dependent invasion
-
172-7
-
Rudrapatna V A, Bangi E and Cagan R L 2013 Caspase signalling in the absence of apoptosis drives Jnk-dependent invasion EMBO Rep. 14 172-7
-
(2013)
EMBO Rep.
, vol.14
, pp. 172-177
-
-
Rudrapatna, V.A.1
Bangi, E.2
Cagan, R.L.3
-
66
-
-
56549114782
-
Leishmania infantum expresses a mitochondrial nuclease homologous to EndoG that migrates to the nucleus in response to an apoptotic stimulus
-
28-38
-
Rico E, Alzate J F, Arias A A, Moreno D, Clos J, Gago F, Moreno I, Domínguez M and Jiménez-Ruiz A 2009 Leishmania infantum expresses a mitochondrial nuclease homologous to EndoG that migrates to the nucleus in response to an apoptotic stimulus Mol. Biochem. Parasitol. 163 28-38
-
(2009)
Mol. Biochem. Parasitol.
, vol.163
, pp. 28-38
-
-
Rico, E.1
Alzate, J.F.2
Arias, A.A.3
Moreno, D.4
Clos, J.5
Gago, F.6
Moreno, I.7
Domínguez, M.8
Jiménez-Ruiz, A.9
-
67
-
-
33846223232
-
Endonuclease G regulates budding yeast life and death
-
233-46
-
Büttner S et al 2007 Endonuclease G regulates budding yeast life and death Mol. Cell 25 233-46
-
(2007)
Mol. Cell
, vol.25
, pp. 233-246
-
-
Büttner, S.1
-
68
-
-
39449083014
-
Conservation of the pro-apoptotic nuclease activity of endonuclease G in unicellular trypanosomatid parasites
-
99-109
-
Gannavaram S, Vedvyas C and Debrabant A 2008 Conservation of the pro-apoptotic nuclease activity of endonuclease G in unicellular trypanosomatid parasites J. Cell Sci. 121 99-109
-
(2008)
J. Cell Sci.
, vol.121
, pp. 99-109
-
-
Gannavaram, S.1
Vedvyas, C.2
Debrabant, A.3
-
69
-
-
0036915257
-
ZEN1 is a key enzyme in the degradation of nuclear DNA during programmed cell death of tracheary elements
-
3201-11
-
Ito J and Fukuda H 2002 ZEN1 is a key enzyme in the degradation of nuclear DNA during programmed cell death of tracheary elements Plant Cell 14 3201-11
-
(2002)
Plant Cell
, vol.14
, pp. 3201-3211
-
-
Ito, J.1
Fukuda, H.2
-
70
-
-
0037159784
-
Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans
-
1587-92
-
Wang X, Yang C, Chai J, Shi Y and Xue D 2002 Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans Science 298 1587-92
-
(2002)
Science
, vol.298
, pp. 1587-1592
-
-
Wang, X.1
Yang, C.2
Chai, J.3
Shi, Y.4
Xue, D.5
-
71
-
-
0031889132
-
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
-
96-9
-
Sakahira H, Enari M and Nagata S 1998 Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis Nature 391 96-9
-
(1998)
Nature
, vol.391
, pp. 96-99
-
-
Sakahira, H.1
Enari, M.2
Nagata, S.3
-
72
-
-
0034724949
-
A novel activation mechanism of caspase-activated DNase from Drosophila melanogaster
-
12978-86
-
Yokoyama H, Mukae N, Sakahira H, Okawa K, Iwamatsu A and Nagata S 2000 A novel activation mechanism of caspase-activated DNase from Drosophila melanogaster J. Biol. Chem. 275 12978-86
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 12978-12986
-
-
Yokoyama, H.1
Mukae, N.2
Sakahira, H.3
Okawa, K.4
Iwamatsu, A.5
Nagata, S.6
-
73
-
-
84888203866
-
Programmed cell death in the marine cyanobacterium Trichodesmium mediates carbon and nitrogen export
-
2340-8
-
Bar-Zeev E, Avishay I, Bidle K D and Berman-Frank I 2013 Programmed cell death in the marine cyanobacterium Trichodesmium mediates carbon and nitrogen export ISME J. 7 2340-8
-
(2013)
ISME J.
, vol.7
, pp. 2340-2348
-
-
Bar-Zeev, E.1
Avishay, I.2
Bidle, K.D.3
Berman-Frank, I.4
-
74
-
-
84858952029
-
Two programmed cell death systems in Escherichia coli: An apoptotic-like death is inhibited by the mazEF-mediated death pathway
-
Erental A, Sharon I and Engelberg-Kulka H 2012 Two programmed cell death systems in Escherichia coli: an apoptotic-like death is inhibited by the mazEF-mediated death pathway PLoS Biol. 10 e1001281
-
(2012)
PLoS Biol.
, vol.10
-
-
Erental, A.1
Sharon, I.2
Engelberg-Kulka, H.3
-
75
-
-
84861978322
-
Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis
-
561-72
-
Dwyer D J, Camacho D M, Kohanski M A, Callura J M and Collins J J 2012 Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis Mol. Cell 46 561-72
-
(2012)
Mol. Cell
, vol.46
, pp. 561-572
-
-
Dwyer, D.J.1
Camacho, D.M.2
Kohanski, M.A.3
Callura, J.M.4
Collins, J.J.5
-
76
-
-
10744230830
-
Chronological aging leads to apoptosis in yeast
-
501-7
-
Herker E, Jungwirth H, Lehmann K A, Maldener C, Fröhlich K U, Wissing S, Büttner S, Fehr M, Sigrist S and Madeo F 2004 Chronological aging leads to apoptosis in yeast J. Cell Biol. 164 501-7
-
(2004)
J. Cell Biol.
, vol.164
, pp. 501-507
-
-
Herker, E.1
Jungwirth, H.2
Lehmann, K.A.3
Maldener, C.4
Fröhlich, K.U.5
Wissing, S.6
Büttner, S.7
Fehr, M.8
Sigrist, S.9
Madeo, F.10
-
77
-
-
4744375969
-
Starvation for an essential amino acid induces apoptosis and oxidative stress in yeast
-
345-53
-
Eisler H, Fröhlich K U and Heidenreich E 2004 Starvation for an essential amino acid induces apoptosis and oxidative stress in yeast Exp. Cell Res. 300 345-53
-
(2004)
Exp. Cell Res.
, vol.300
, pp. 345-353
-
-
Eisler, H.1
Fröhlich, K.U.2
Heidenreich, E.3
-
78
-
-
0037007151
-
Pheromone induces programmed cell death in S. Cerevisiae
-
R233-5
-
Severin F F and Hyman A A 2002 Pheromone induces programmed cell death in S. cerevisiae Curr. Biol. 12 R233-5
-
(2002)
Curr. Biol.
, vol.12
, pp. R233-R235
-
-
Severin, F.F.1
Hyman, A.A.2
-
79
-
-
77950857972
-
Apoptosis in yeast: Triggers, pathways, subroutines
-
763-73
-
Carmona-Gutierrez D, Eisenberg T, Büttner S, Meisinger C, Kroemer G and Madeo F 2010 Apoptosis in yeast: triggers, pathways, subroutines Cell Death Differ. 17 763-73
-
(2010)
Cell Death Differ.
, vol.17
, pp. 763-773
-
-
Carmona-Gutierrez, D.1
Eisenberg, T.2
Büttner, S.3
Meisinger, C.4
Kroemer, G.5
Madeo, F.6
-
81
-
-
84855266765
-
The meaning of death: Evolution and ecology of apoptosis in protozoan parasites
-
Reece S E, Pollitt L C, Colegrave N and Gardner A 2011 The meaning of death: evolution and ecology of apoptosis in protozoan parasites PLoS Pathogens 7 e1002320
-
(2011)
PLoS Pathogens
, vol.7
-
-
Reece, S.E.1
Pollitt, L.C.2
Colegrave, N.3
Gardner, A.4
-
82
-
-
0000055057
-
Pleiotropy, natural selection, and the evolution of senescence
-
398-411
-
George C C W 1957 Pleiotropy, natural selection, and the evolution of senescence Evolution 11 398-411
-
(1957)
Evolution
, vol.11
, pp. 398-411
-
-
George, C.C.W.1
-
83
-
-
7744246367
-
Life's smile, death's grin: Vital functions of apoptosis-executing proteins
-
639-46
-
Garrido C and Kroemer G 2004 Life's smile, death's grin: vital functions of apoptosis-executing proteins Curr. Opin. Cell Biol. 16 639-46
-
(2004)
Curr. Opin. Cell Biol.
, vol.16
, pp. 639-646
-
-
Garrido, C.1
Kroemer, G.2
-
84
-
-
33750341991
-
Apoptosis-like death as a feature of malaria infection in mosquitoes
-
S33-47
-
Hurd H, Grant K and Arambage S 2006 Apoptosis-like death as a feature of malaria infection in mosquitoes Parasitology 132 S33-47
-
(2006)
Parasitology
, vol.132
, pp. S33-S47
-
-
Hurd, H.1
Grant, K.2
Arambage, S.3
-
85
-
-
84948614578
-
The molecular ecophysiology of programmed cell death in marine phytoplankton
-
341-75
-
Bidle K D 2015 The molecular ecophysiology of programmed cell death in marine phytoplankton Annu. Rev. Mar. Sci. 7 341-75
-
(2015)
Annu. Rev. Mar. Sci.
, vol.7
, pp. 341-375
-
-
Bidle, K.D.1
-
86
-
-
0033598203
-
Programmed cell death of the dinoflagellate Peridinium gatunense is mediated by CO(2) limitation and oxidative stress
-
1061-4
-
Vardi A, Berman-Frank I, Rozenberg T, Hadas O, Kaplan A and Levine A 1999 Programmed cell death of the dinoflagellate Peridinium gatunense is mediated by CO(2) limitation and oxidative stress Curr. Biol. 9 1061-4
-
(1999)
Curr. Biol.
, vol.9
, pp. 1061-1064
-
-
Vardi, A.1
Berman-Frank, I.2
Rozenberg, T.3
Hadas, O.4
Kaplan, A.5
Levine, A.6
-
87
-
-
79751479263
-
How an organism dies affects the fitness of its neighbors
-
224-32
-
Durand P M, Rashidi A and Michod R E 2011 How an organism dies affects the fitness of its neighbors Am. Nat. 177 224-32
-
(2011)
Am. Nat.
, vol.177
, pp. 224-232
-
-
Durand, P.M.1
Rashidi, A.2
Michod, R.E.3
-
88
-
-
84896534612
-
Programmed death in a unicellular organism has species-specific fitness effects
-
Durand P M, Choudhury R, Rashidi A and Michod R E 2014 Programmed death in a unicellular organism has species-specific fitness effects Biol. Lett. 10 20131088
-
(2014)
Biol. Lett.
, vol.10
-
-
Durand, P.M.1
Choudhury, R.2
Rashidi, A.3
Michod, R.E.4
-
89
-
-
84875296529
-
Altruism can evolve when relatedness is low: Evidence from bacteria committing suicide upon phage infection
-
Refardt D, Bergmiller T and Kümmerli R 2013 Altruism can evolve when relatedness is low: evidence from bacteria committing suicide upon phage infection Proc. Biol. Sci. 280 20123035
-
(2013)
Proc. Biol. Sci.
, vol.280
-
-
Refardt, D.1
Bergmiller, T.2
Kümmerli, R.3
-
90
-
-
34347226350
-
Viral activation and recruitment of metacaspases in the unicellular coccolithophore, Emiliania huxleyi
-
6049-54
-
Bidle K D, Haramaty L, Barcelos E, Ramos J and Falkowski P 2007 Viral activation and recruitment of metacaspases in the unicellular coccolithophore, Emiliania huxleyi Proc. Natl Acad. Sci. USA 104 6049-54
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 6049-6054
-
-
Bidle, K.D.1
Haramaty, L.2
Barcelos, E.3
Ramos, J.4
Falkowski, P.5
-
91
-
-
0013915372
-
The structural gene for yeast cytochrome C
-
1498-504
-
Sherman F, Stewart J W, Margoliash E, Parker J and Campbell W 1966 The structural gene for yeast cytochrome C Proc. Natl Acad. Sci. USA 55 1498-504
-
(1966)
Proc. Natl Acad. Sci. USA
, vol.55
, pp. 1498-1504
-
-
Sherman, F.1
Stewart, J.W.2
Margoliash, E.3
Parker, J.4
Campbell, W.5
-
92
-
-
77955791979
-
Metacaspase Yca1 is required for clearance of insoluble protein aggregates
-
13348-53
-
Lee R E, Brunette S, Puente L G and Megeney L A 2010 Metacaspase Yca1 is required for clearance of insoluble protein aggregates Proc. Natl Acad. Sci. USA 107 13348-53
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 13348-13353
-
-
Lee, R.E.1
Brunette, S.2
Puente, L.G.3
Megeney, L.A.4
-
93
-
-
51849114272
-
A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics
-
Lee R E, Puente L G, Kaern M and Megeney L A 2008 A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics PLoS One 3 e2956
-
(2008)
PLoS One
, vol.3
-
-
Lee, R.E.1
Puente, L.G.2
Kaern, M.3
Megeney, L.A.4
-
95
-
-
0026470567
-
Programmed nuclear death: Apoptotic-like degradation of specific nuclei in conjugating Tetrahymena
-
419-32
-
Davis M C, Ward J G, Herrick G and Allis C D 1992 Programmed nuclear death: apoptotic-like degradation of specific nuclei in conjugating Tetrahymena Dev. Biol. 154 419-32
-
(1992)
Dev. Biol.
, vol.154
, pp. 419-432
-
-
Davis, M.C.1
Ward, J.G.2
Herrick, G.3
Allis, C.D.4
-
96
-
-
1642442429
-
Developmental cell death in dictyostelium does not require paracaspase
-
11489-94
-
Roisin-Bouffay C, Luciani M F, Klein G, Levraud J P, Adam M and Golstein P 2004 Developmental cell death in dictyostelium does not require paracaspase J. Biol. Chem. 279 11489-94
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 11489-11494
-
-
Roisin-Bouffay, C.1
Luciani, M.F.2
Klein, G.3
Levraud, J.P.4
Adam, M.5
Golstein, P.6
-
97
-
-
0031419356
-
Programmed cell death in plants
-
1157-68
-
Pennell R I and Lamb C 1997 Programmed cell death in plants Plant Cell 9 1157-68
-
(1997)
Plant Cell
, vol.9
, pp. 1157-1168
-
-
Pennell, R.I.1
Lamb, C.2
-
98
-
-
0034162885
-
Programmed cell death and aerenchyma formation in roots
-
123-7
-
Drew M C, He C J and Morgan P W 2000 Programmed cell death and aerenchyma formation in roots Trends Plant Sci. 5 123-7
-
(2000)
Trends Plant Sci.
, vol.5
, pp. 123-127
-
-
Drew, M.C.1
He, C.J.2
Morgan, P.W.3
-
99
-
-
27744587203
-
Programmed cell death progressively models the development of anther sporophytic tissues from the tapetum and is triggered in pollen grains during maturation
-
118-28
-
Varnier A L, Mazeyrat-Gourbeyre F, Sangwan R S and Clément C 2005 Programmed cell death progressively models the development of anther sporophytic tissues from the tapetum and is triggered in pollen grains during maturation J. Struct. Biol. 152 118-28
-
(2005)
J. Struct. Biol.
, vol.152
, pp. 118-128
-
-
Varnier, A.L.1
Mazeyrat-Gourbeyre, F.2
Sangwan, R.S.3
Clément, C.4
-
100
-
-
0035211891
-
Apoptosis - A death-inducing mechanism tightly linked with morphogenesis in Hydractina echinata (Cnidaria, Hydrozoa)
-
4891-8
-
Seipp S, Schmich J and Leitz T 2001 Apoptosis - a death-inducing mechanism tightly linked with morphogenesis in Hydractina echinata (Cnidaria, Hydrozoa) Development 128 4891-8
-
(2001)
Development
, vol.128
, pp. 4891-4898
-
-
Seipp, S.1
Schmich, J.2
Leitz, T.3
-
101
-
-
31344452957
-
Metamorphosis of Hydractinia echinata (Cnidaria) is caspase-dependent
-
63-70
-
Seipp S, Wittig K, Stiening B, Böttger A and Leitz T 2006 Metamorphosis of Hydractinia echinata (Cnidaria) is caspase-dependent Int. J. Dev. Biol. 50 63-70
-
(2006)
Int. J. Dev. Biol.
, vol.50
, pp. 63-70
-
-
Seipp, S.1
Wittig, K.2
Stiening, B.3
Böttger, A.4
Leitz, T.5
-
102
-
-
1642514774
-
Men are but worms: Neuronal cell death in C. Elegans and vertebrates
-
38-48
-
Putcha G V and Johnson E M 2004 Men are but worms: neuronal cell death in C. Elegans and vertebrates Cell Death Differ. 11 38-48
-
(2004)
Cell Death Differ.
, vol.11
, pp. 38-48
-
-
Putcha, G.V.1
Johnson, E.M.2
-
103
-
-
38049125671
-
Apoptosis in the development of the immune system
-
234-42
-
Opferman J T 2008 Apoptosis in the development of the immune system Cell Death Differ. 15 234-42
-
(2008)
Cell Death Differ.
, vol.15
, pp. 234-242
-
-
Opferman, J.T.1
-
105
-
-
13944272143
-
Aging and death in an organism that reproduces by morphologically symmetric division
-
Stewart E J, Madden R, Paul G and Taddei F 2005 Aging and death in an organism that reproduces by morphologically symmetric division PLoS Biol. 3 e45
-
(2005)
PLoS Biol.
, vol.3
, pp. e45
-
-
Stewart, E.J.1
Madden, R.2
Paul, G.3
Taddei, F.4
-
106
-
-
42949100420
-
Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation
-
3076-81
-
Lindner A B, Madden R, Demarez A, Stewart E J and Taddei F 2008 Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation Proc. Natl Acad. Sci. USA 105 3076-81
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 3076-3081
-
-
Lindner, A.B.1
Madden, R.2
Demarez, A.3
Stewart, E.J.4
Taddei, F.5
-
107
-
-
27744471409
-
A comparison of the aging and apoptotic transcriptome of Saccharomyces cerevisiae
-
1261-72
-
Laun P et al 2005 A comparison of the aging and apoptotic transcriptome of Saccharomyces cerevisiae FEMS Yeast Res. 5 1261-72
-
(2005)
FEMS Yeast Res.
, vol.5
, pp. 1261-1272
-
-
Laun, P.1
-
109
-
-
34548727395
-
The chronological life span of Saccharomyces cerevisiae
-
89-95
-
Fabrizio P and Longo V D 2007 The chronological life span of Saccharomyces cerevisiae Methods Mol. Biol. 371 89-95
-
(2007)
Methods Mol. Biol.
, vol.371
, pp. 89-95
-
-
Fabrizio, P.1
Longo, V.D.2
-
110
-
-
77950214581
-
Lessons on longevity from budding yeast
-
513-9
-
Kaeberlein M 2010 Lessons on longevity from budding yeast Nature 464 513-9
-
(2010)
Nature
, vol.464
, pp. 513-519
-
-
Kaeberlein, M.1
-
111
-
-
33745377897
-
Yeast AMID homologue Ndi1p displays respiration-restricted apoptotic activity and is involved in chronological aging
-
1802-11
-
Li W, Sun L, Liang Q, Wang J, Mo W and Zhou B 2006 Yeast AMID homologue Ndi1p displays respiration-restricted apoptotic activity and is involved in chronological aging Mol. Biol. Cell 17 1802-11
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 1802-1811
-
-
Li, W.1
Sun, L.2
Liang, Q.3
Wang, J.4
Mo, W.5
Zhou, B.6
-
112
-
-
0035961329
-
The structural basis of protein folding and its links with human disease
-
133-45
-
Dobson C M 2001 The structural basis of protein folding and its links with human disease Phil. Trans. R. Soc. London B 356 133-45
-
(2001)
Phil. Trans. R. Soc. London
, vol.356
, pp. 133-145
-
-
Dobson, C.M.1
-
113
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
481-4
-
Kujoth G C et al 2005 Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging Science 309 481-4
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
-
114
-
-
84876245548
-
Mitochondria and the evolutionary roots of cancer
-
Davila A F and Zamorano P 2013 Mitochondria and the evolutionary roots of cancer Phys. Biol. 10 026008
-
(2013)
Phys. Biol.
, vol.10
, Issue.2
-
-
Davila, A.F.1
Zamorano, P.2
-
115
-
-
0031736203
-
Somatic mutations of the mitochondrial genome in human colorectal tumours
-
291-3
-
Polyak K, Li Y, Zhu H, Lengauer C, Willson J K, Markowitz S D, Trush M A, Kinzler K W and Vogelstein B 1998 Somatic mutations of the mitochondrial genome in human colorectal tumours Nat. Genet. 20 291-3
-
(1998)
Nat. Genet.
, vol.20
, pp. 291-293
-
-
Polyak, K.1
Li, Y.2
Zhu, H.3
Lengauer, C.4
Willson, J.K.5
Markowitz, S.D.6
Trush, M.A.7
Kinzler, K.W.8
Vogelstein, B.9
-
116
-
-
0039250954
-
Facile detection of mitochondrial DNA mutations in tumors and bodily fluids
-
2017-9
-
Fliss M S, Usadel H, Caballero O L, Wu L, Buta M R, Eleff S M, Jen J and Sidransky D 2000 Facile detection of mitochondrial DNA mutations in tumors and bodily fluids Science 287 2017-9
-
(2000)
Science
, vol.287
, pp. 2017-2019
-
-
Fliss, M.S.1
Usadel, H.2
Caballero, O.L.3
Wu, L.4
Buta, M.R.5
Eleff, S.M.6
Jen, J.7
Sidransky, D.8
-
117
-
-
43249112094
-
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis
-
661-4
-
Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H, Nakada K, Honma Y and Hayashi J 2008 ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis Science 320 661-4
-
(2008)
Science
, vol.320
, pp. 661-664
-
-
Ishikawa, K.1
Takenaga, K.2
Akimoto, M.3
Koshikawa, N.4
Yamaguchi, A.5
Imanishi, H.6
Nakada, K.7
Honma, Y.8
Hayashi, J.9
-
118
-
-
84868205667
-
Mitochondria organelle transplantation: Introduction of normal epithelial mitochondria into human cancer cells inhibits proliferation and increases drug sensitivity
-
347-54
-
Elliott R L, Jiang X P and Head J F 2012 Mitochondria organelle transplantation: introduction of normal epithelial mitochondria into human cancer cells inhibits proliferation and increases drug sensitivity Breast Cancer Res. Treat. 136 347-54
-
(2012)
Breast Cancer Res. Treat.
, vol.136
, pp. 347-354
-
-
Elliott, R.L.1
Jiang, X.P.2
Head, J.F.3
-
119
-
-
0035902115
-
Proliferation, cell cycle and apoptosis in cancer
-
342-8
-
Evan G I and Vousden K H 2001 Proliferation, cell cycle and apoptosis in cancer Nature 411 342-8
-
(2001)
Nature
, vol.411
, pp. 342-348
-
-
Evan, G.I.1
Vousden, K.H.2
-
120
-
-
13844280932
-
Apoptosis in the development and treatment of cancer
-
263-70
-
Gerl R and Vaux D L 2005 Apoptosis in the development and treatment of cancer Carcinogenesis 26 263-70
-
(2005)
Carcinogenesis
, vol.26
, pp. 263-270
-
-
Gerl, R.1
Vaux, D.L.2
-
121
-
-
0036463370
-
Apoptosis-based anticancer drugs
-
101-2
-
Zhang J Y 2002 Apoptosis-based anticancer drugs Nat. Rev. Drug Discovery 1 101-2
-
(2002)
Nat. Rev. Drug Discovery
, vol.1
, pp. 101-102
-
-
Zhang, J.Y.1
-
122
-
-
0034662604
-
Mutations of the bak gene in human gastric and colorectal cancers
-
4328-30
-
Kondo S, Shinomura Y, Miyazaki Y, Kiyohara T, Tsutsui S, Kitamura S, Nagasawa Y, Nakahara M, Kanayama S and Matsuzawa Y 2000 Mutations of the bak gene in human gastric and colorectal cancers Cancer Res. 60 4328-30
-
(2000)
Cancer Res.
, vol.60
, pp. 4328-4330
-
-
Kondo, S.1
Shinomura, Y.2
Miyazaki, Y.3
Kiyohara, T.4
Tsutsui, S.5
Kitamura, S.6
Nagasawa, Y.7
Nakahara, M.8
Kanayama, S.9
Matsuzawa, Y.10
-
123
-
-
9244224723
-
Intrinsic tumour suppression
-
307-15
-
Lowe S W, Cepero E and Evan G 2004 Intrinsic tumour suppression Nature 432 307-15
-
(2004)
Nature
, vol.432
, pp. 307-315
-
-
Lowe, S.W.1
Cepero, E.2
Evan, G.3
-
124
-
-
84879165160
-
Oxidative stress: The mitochondria-dependent and mitochondria-independent pathways of apoptosis
-
1157-80
-
Sinha K, Das J, Pal P B and Sil P C 2013 Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis Arch. Toxicol. 87 1157-80
-
(2013)
Arch. Toxicol.
, vol.87
, pp. 1157-1180
-
-
Sinha, K.1
Das, J.2
Pal, P.B.3
Sil, P.C.4
-
125
-
-
74049135504
-
Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris
-
1-84
-
Boveri T 2008 Concerning the origin of malignant tumours by Theodor Boveri. Translated and annotated by Henry Harris J. Cell Sci. 121 1-84
-
(2008)
J. Cell Sci.
, vol.121
, pp. 1-84
-
-
Boveri, T.1
-
126
-
-
0035902108
-
Genome maintenance mechanisms for preventing cancer
-
366-74
-
Hoeijmakers J H 2001 Genome maintenance mechanisms for preventing cancer Nature 411 366-74
-
(2001)
Nature
, vol.411
, pp. 366-374
-
-
Hoeijmakers, J.H.1
-
127
-
-
10444226461
-
The role of p53-mediated apoptosis as a crucial anti-tumor response to genomic instability: Lessons from mouse models
-
145-57
-
Attardi L D 2005 The role of p53-mediated apoptosis as a crucial anti-tumor response to genomic instability: lessons from mouse models Mutat. Res. 569 145-57
-
(2005)
Mutat. Res.
, vol.569
, pp. 145-157
-
-
Attardi, L.D.1
-
128
-
-
34547121206
-
Hypoxia in cancer: Significance and impact on clinical outcome
-
225-39
-
Vaupel P and Mayer A 2007 Hypoxia in cancer: significance and impact on clinical outcome Cancer Metastasis Rev. 26 225-39
-
(2007)
Cancer Metastasis Rev.
, vol.26
, pp. 225-239
-
-
Vaupel, P.1
Mayer, A.2
-
130
-
-
0035843123
-
Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53
-
147-55
-
Bacus S S, Gudkov A V, Lowe M, Lyass L, Yung Y, Komarov A P, Keyomarsi K, Yarden Y and Seger R 2001 Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53 Oncogene 20 147-55
-
(2001)
Oncogene
, vol.20
, pp. 147-155
-
-
Bacus, S.S.1
Gudkov, A.V.2
Lowe, M.3
Lyass, L.4
Yung, Y.5
Komarov, A.P.6
Keyomarsi, K.7
Yarden, Y.8
Seger, R.9
-
131
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
433-9
-
Zhou B B and Elledge S J 2000 The DNA damage response: putting checkpoints in perspective Nature 408 433-9
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
132
-
-
12444279265
-
On the origin of cancer cells
-
309-14
-
Warburg O 1956 On the origin of cancer cells Science 123 309-14
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
134
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
230-3
-
Christofk H R, Vander Heiden M G, Harris M H, Ramanathan A, Gerszten R E, Wei R, Fleming M D, Schreiber S L and Cantley L C 2008 The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth Nature 452 230-3
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
135
-
-
84885589840
-
PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells
-
397-409
-
Israelsen W J et al 2013 PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells Cell 155 397-409
-
(2013)
Cell
, vol.155
, pp. 397-409
-
-
Israelsen, W.J.1
-
136
-
-
84890695935
-
Tumour-associated mutant p53 drives the Warburg effect
-
Zhang C et al 2013 Tumour-associated mutant p53 drives the Warburg effect Nat. Commun. 4 2935
-
(2013)
Nat. Commun.
, vol.4
, pp. 2935
-
-
Zhang, C.1
-
137
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
1029-33
-
Vander Heiden M G, Cantley L C and Thompson C B 2009 Understanding the Warburg effect: the metabolic requirements of cell proliferation Science 324 1029-33
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
138
-
-
84876231133
-
The Warburg effect version 2.0: Metabolic reprogramming of cancer stem cells
-
1166-79
-
Menendez J A, Joven J, Cufí S, Corominas-Faja B, Oliveras-Ferraros C, Cuyàs E, Martin-Castillo B, López-Bonet E, Alarcón T and Vazquez-Martin A 2013 The Warburg effect version 2.0: metabolic reprogramming of cancer stem cells Cell Cycle 12 1166-79
-
(2013)
Cell Cycle
, vol.12
, pp. 1166-1179
-
-
Menendez, J.A.1
Joven, J.2
Cufí, S.3
Corominas-Faja, B.4
Oliveras-Ferraros, C.5
Cuyàs, E.6
Martin-Castillo, B.7
López-Bonet, E.8
Alarcón, T.9
Vazquez-Martin, A.10
-
139
-
-
33644560281
-
Cancer stem cells: An old idea - A paradigm shift
-
1883-90 discussion 1895-1886
-
Wicha M S, Liu S and Dontu G 2006 Cancer stem cells: an old idea - a paradigm shift Cancer Res. 66 1883-90 discussion 1895-1886
-
(2006)
Cancer Res.
, vol.66
, pp. 1883-1890
-
-
Wicha, M.S.1
Liu, S.2
Dontu, G.3
-
141
-
-
0017928819
-
Whole-embryo culture and the study of mammalian embryos during organogenesis
-
81-122
-
New D A 1978 Whole-embryo culture and the study of mammalian embryos during organogenesis Biol. Rev. Camb. Phil. Soc. 53 81-122
-
(1978)
Biol. Rev. Camb. Phil. Soc.
, vol.53
, pp. 81-122
-
-
New, D.A.1
-
142
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
663-76
-
Takahashi K and Yamanaka S 2006 Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 663-76
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
143
-
-
84857407549
-
Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
-
2784-9
-
Conley S J, Gheordunescu E, Kakarala P, Newman B, Korkaya H, Heath A N, Clouthier S G and Wicha M S 2012 Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia Proc. Natl Acad. Sci. USA 109 2784-9
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 2784-2789
-
-
Conley, S.J.1
Gheordunescu, E.2
Kakarala, P.3
Newman, B.4
Korkaya, H.5
Heath, A.N.6
Clouthier, S.G.7
Wicha, M.S.8
-
144
-
-
84873160542
-
Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells
-
30-54
-
Mimeault M and Batra S K 2013 Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells J. Cell Mol. Med. 17 30-54
-
(2013)
J. Cell Mol. Med.
, vol.17
, pp. 30-54
-
-
Mimeault, M.1
Batra, S.K.2
-
145
-
-
33846002728
-
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
-
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth 37-51
-
Bonnet S et al 2007 A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth Cancer Cell 11 37-51
-
(2007)
Cancer Cell
, vol.11
, pp. 37-51
-
-
Bonnet, S.1
-
146
-
-
52649107626
-
Cancer cell metabolism: Warburg and beyond
-
703-7
-
Hsu P P and Sabatini D M 2008 Cancer cell metabolism: Warburg and beyond Cell 134 703-7
-
(2008)
Cell
, vol.134
, pp. 703-707
-
-
Hsu, P.P.1
Sabatini, D.M.2
-
147
-
-
0021811271
-
Low cancer rates among patients with Parkinson's disease
-
505-9
-
Jansson B and Jankovic J 1985 Low cancer rates among patients with Parkinson's disease Ann. Neurol. 17 505-9
-
(1985)
Ann. Neurol.
, vol.17
, pp. 505-509
-
-
Jansson, B.1
Jankovic, J.2
-
148
-
-
84881295894
-
Inverse occurrence of cancer and Alzheimer disease: A population-based incidence study
-
322-8
-
Musicco M, Adorni F, Di Santo S, Prinelli F, Pettenati C, Caltagirone C, Palmer K and Russo A 2013 Inverse occurrence of cancer and Alzheimer disease: a population-based incidence study Neurology 81 322-8
-
(2013)
Neurology
, vol.81
, pp. 322-328
-
-
Musicco, M.1
Adorni, F.2
Di Santo, S.3
Prinelli, F.4
Pettenati, C.5
Caltagirone, C.6
Palmer, K.7
Russo, A.8
-
149
-
-
20744453647
-
To die or grow: Parkinson's disease and cancer
-
348-52
-
West A B, Dawson V L and Dawson T M 2005 To die or grow: Parkinson's disease and cancer Trends Neurosci. 28 348-52
-
(2005)
Trends Neurosci.
, vol.28
, pp. 348-352
-
-
West, A.B.1
Dawson, V.L.2
Dawson, T.M.3
-
150
-
-
84859192682
-
Inverse association between cancer and Alzheimer's disease: Results from the Framingham Heart Study
-
Driver J A, Beiser A, Au R, Kreger B E, Splansky G L, Kurth T, Kiel D P, Lu K P, Seshadri S and Wolf P A 2012 Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study BMJ 344 e1442
-
(2012)
BMJ
, vol.344
-
-
Driver, J.A.1
Beiser, A.2
Au, R.3
Kreger, B.E.4
Splansky, G.L.5
Kurth, T.6
Kiel, D.P.7
Lu, K.P.8
Seshadri, S.9
Wolf, P.A.10
-
151
-
-
84940902321
-
Alzheimer's disease: The amyloid hypothesis and the Inverse Warburg effect
-
Demetrius L A, Magistretti P J and Pellerin L 2014 Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect Frontiers Physiol. 5 522
-
(2014)
Frontiers Physiol.
, vol.5
, pp. 522
-
-
Demetrius, L.A.1
Magistretti, P.J.2
Pellerin, L.3
-
152
-
-
0029942337
-
Histochemical detection of apoptosis in Parkinson's disease
-
120-3
-
Mochizuki H, Goto K, Mori H and Mizuno Y 1996 Histochemical detection of apoptosis in Parkinson's disease J. Neurol. Sci. 137 120-3
-
(1996)
J. Neurol. Sci.
, vol.137
, pp. 120-123
-
-
Mochizuki, H.1
Goto, K.2
Mori, H.3
Mizuno, Y.4
-
153
-
-
0028981717
-
The Alzheimer's A β peptide induces neurodegeneration and apoptotic cell death in transgenic mice
-
21-30
-
LaFerla F M, Tinkle B T, Bieberich C J, Haudenschild C C and Jay G 1995 The Alzheimer's A β peptide induces neurodegeneration and apoptotic cell death in transgenic mice Nat. Genet. 9 21-30
-
(1995)
Nat. Genet.
, vol.9
, pp. 21-30
-
-
LaFerla, F.M.1
Tinkle, B.T.2
Bieberich, C.J.3
Haudenschild, C.C.4
Jay, G.5
|