-
1
-
-
33646807832
-
The P53 pathway: What questions remain to be explored?
-
Levine, A. J., Hu, W. & Feng, Z. The P53 pathway: what questions remain to be explored? Cell Death Differ. 13, 1027-1036 (2006).
-
(2006)
Cell Death Differ.
, vol.13
, pp. 1027-1036
-
-
Levine, A.J.1
Hu, W.2
Feng, Z.3
-
2
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
Vousden, K. H. & Prives, C. Blinded by the light: the growing complexity of p53. Cell 137, 413-431 (2009).
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
3
-
-
70349442548
-
The first 30 years of p53: Growing ever more complex
-
Levine, A. J. & Oren, M. The first 30 years of p53: growing ever more complex. Nat. Rev. Cancer 9, 749-758 (2009).
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 749-758
-
-
Levine, A.J.1
Oren, M.2
-
4
-
-
77649298024
-
Modulation of the vitamin D3 response by cancerassociated mutant p53
-
Stambolsky, P. et al. Modulation of the vitamin D3 response by cancerassociated mutant p53. Cancer Cell 17, 273-285 (2010).
-
(2010)
Cancer Cell
, vol.17
, pp. 273-285
-
-
Stambolsky, P.1
-
5
-
-
72249100428
-
Mutant p53 drives invasion by promoting integrin recycling
-
Muller, P. A. et al. Mutant p53 drives invasion by promoting integrin recycling. Cell 139, 1327-1341 (2009).
-
(2009)
Cell
, vol.139
, pp. 1327-1341
-
-
Muller, P.A.1
-
7
-
-
84862908644
-
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
-
Freed-Pastor, W. A. et al. Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell 148, 244-258 (2012).
-
(2012)
Cell
, vol.148
, pp. 244-258
-
-
Freed-Pastor, W.A.1
-
8
-
-
13644260907
-
Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome
-
DOI 10.1016/j.cell.2004.11.006, PII S0092867404010487
-
Lang, G. A. et al. Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome. Cell 119, 861-872 (2004). (Pubitemid 40017691)
-
(2004)
Cell
, vol.119
, Issue.6
, pp. 861-872
-
-
Lang, G.A.1
Iwakuma, T.2
Suh, Y.-A.3
Liu, G.4
Rao, V.A.5
Parant, J.M.6
Valentin-Vega, Y.A.7
Terzian, T.8
Caldwell, L.C.9
Strong, L.C.10
El-Naggar, A.K.11
Lozano, G.12
-
9
-
-
10944236962
-
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome
-
DOI 10.1016/j.cell.2004.11.004, PII S0092867404010463
-
Olive, K. P. et al. Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell 119, 847-860 (2004). (Pubitemid 40017690)
-
(2004)
Cell
, vol.119
, Issue.6
, pp. 847-860
-
-
Olive, K.P.1
Tuveson, D.A.2
Ruhe, Z.C.3
Yin, B.4
Willis, N.A.5
Bronson, R.T.6
Crowley, D.7
Jacks, T.8
-
10
-
-
77954310492
-
The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein
-
Feng, Z. & Levine, A. J. The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein. Trends Cell Biol. 20, 427-434 (2010).
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 427-434
-
-
Feng, Z.1
Levine, A.J.2
-
11
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan, D. & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell 144, 646-674 (2011).
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
13
-
-
78649711427
-
The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes
-
Levine, A. J. & Puzio-Kuter, A. M. The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes. Science 330, 1340-1344 (2010).
-
(2010)
Science
, vol.330
, pp. 1340-1344
-
-
Levine, A.J.1
Puzio-Kuter, A.M.2
-
14
-
-
12444279265
-
On the origin of cancer cells
-
Warburg, O. On the origin of cancer cells. Science 123, 309-314 (1956).
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
15
-
-
33744783432
-
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
-
DOI 10.1016/j.ccr.2006.04.023, PII S1535610806001450
-
Fantin, V. R., St-Pierre, J. & Leder, P. Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell 9, 425-434 (2006). (Pubitemid 43832190)
-
(2006)
Cancer Cell
, vol.9
, Issue.6
, pp. 425-434
-
-
Fantin, V.R.1
St-Pierre, J.2
Leder, P.3
-
16
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
DOI 10.1038/nature06734, PII NATURE06734
-
Christofk, H. R. et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 452, 230-233 (2008). (Pubitemid 351380249)
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
Fleming, M.D.7
Schreiber, S.L.8
Cantley, L.C.9
-
18
-
-
84861973567
-
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
-
Li, T. et al. Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence. Cell 149, 1269-1283 (2012).
-
(2012)
Cell
, vol.149
, pp. 1269-1283
-
-
Li, T.1
-
19
-
-
33745918951
-
TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis
-
DOI 10.1016/j.cell.2006.05.036, PII S0092867406007628
-
Bensaad, K. et al. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 126, 107-120 (2006). (Pubitemid 44040989)
-
(2006)
Cell
, vol.126
, Issue.1
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.C.4
Nakano, K.5
Bartrons, R.6
Gottlieb, E.7
Vousden, K.H.8
-
20
-
-
33745149291
-
P53 regulates mitochondrial respiration
-
DOI 10.1126/science.1126863
-
Matoba, S. et al. p53 regulates mitochondrial respiration. Science 312, 1650-1653 (2006). (Pubitemid 43902663)
-
(2006)
Science
, vol.312
, Issue.5780
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.-G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
Hurley, P.J.7
Bunz, F.8
Hwang, P.M.9
-
21
-
-
80053635472
-
Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect
-
Zhang, C. et al. Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect. Proc. Natl Acad. Sci. USA 108, 16259-16264 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 16259-16264
-
-
Zhang, C.1
-
22
-
-
77952212178
-
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
-
Hu, W. et al. Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function. Proc. Natl Acad. Sci. USA 107, 7455-7460 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 7455-7460
-
-
Hu, W.1
-
23
-
-
84859215796
-
Systemic elevation of PTEN induces a tumor-suppressive metabolic state
-
Garcia-Cao, I. et al. Systemic elevation of PTEN induces a tumor-suppressive metabolic state. Cell 149, 49-62 (2012).
-
(2012)
Cell
, vol.149
, pp. 49-62
-
-
Garcia-Cao, I.1
-
24
-
-
79952775519
-
Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance
-
Fang, S. et al. Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance. Proc. Natl Acad. Sci. USA 108, 3412-3417 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 3412-3417
-
-
Fang, S.1
-
25
-
-
84861890085
-
Regulation of glucose transporter translocation in health and diabetes.
-
Bogan, J. S. Regulation of glucose transporter translocation in health and diabetes. Annu. Rev. Biochem. 81, 507-532 (2012).
-
(2012)
Annu. Rev. Biochem.
, vol.81
, pp. 507-532
-
-
Bogan, J.S.1
-
26
-
-
57749111596
-
Nutrient transporters in cancer: Relevance to Warburg hypothesis and beyond.
-
Ganapathy, V., Thangaraju, M. & Prasad, P. D. Nutrient transporters in cancer: relevance to Warburg hypothesis and beyond. Pharmacol. Ther. 121, 29-40 (2009).
-
(2009)
Pharmacol. Ther.
, vol.121
, pp. 29-40
-
-
Ganapathy, V.1
Thangaraju, M.2
Prasad, P.D.3
-
27
-
-
84872478184
-
Expression of glucose transporters in cancers.
-
Szablewski, L. Expression of glucose transporters in cancers. Biochim. Biophys. Acta 1835, 164-169 (2012).
-
(2012)
Biochim. Biophys. Acta
, vol.1835
, pp. 164-169
-
-
Szablewski, L.1
-
28
-
-
0141891296
-
Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface
-
DOI 10.1074/jbc.M305689200
-
Bentley, J. et al. Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface. J. Biol. Chem. 278, 39337-39348 (2003). (Pubitemid 37248489)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.41
, pp. 39337-39348
-
-
Bentley, J.1
Itchayanan, D.2
Barnes, K.3
McIntosh, E.4
Tang, X.5
Downes, C.P.6
Holman, G.D.7
Whetton, A.D.8
Owen-Lynch, P.J.9
Baldwin, S.A.10
-
29
-
-
33748994545
-
Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking
-
DOI 10.1016/j.tcb.2006.08.006, PII S0962892406002236, Membrane Dynamics
-
Ridley, A. J. Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol. 16, 522-529 (2006). (Pubitemid 44444995)
-
(2006)
Trends in Cell Biology
, vol.16
, Issue.10
, pp. 522-529
-
-
Ridley, A.J.1
-
30
-
-
70349187211
-
Rho GTPase function in tumorigenesis
-
Karlsson, R., Pedersen, E. D., Wang, Z. & Brakebusch, C. Rho GTPase function in tumorigenesis. Biochim. Biophys. Acta 1796, 91-98 (2009).
-
(2009)
Biochim. Biophys. Acta
, vol.1796
, pp. 91-98
-
-
Karlsson, R.1
Pedersen, E.D.2
Wang, Z.3
Brakebusch, C.4
-
32
-
-
37249087851
-
Small G proteins in insulin action: Rab and Rho families at the crossroads of signal transduction and GLUT4 vesicle traffic
-
DOI 10.1111/j.1748-1716.2007.01778.x
-
Ishikura, S., Koshkina, A. & Klip, A. Small G proteins in insulin action: Rab and Rho families at the crossroads of signal transduction and GLUT4 vesicle traffic. Acta Physiol. (Oxf) 192, 61-74, 2008). (Pubitemid 350265359)
-
(2008)
Acta Physiologica
, vol.192
, Issue.1
, pp. 61-74
-
-
Ishikura, S.1
Koshkina, A.2
Klip, A.3
-
33
-
-
0032571004
-
Comparative effects of GTPγS and insulin on the activation of Rho, phosphatidylinositol 3-kinase, and protein kinase N in Rat adipocytes. Relationship to glucose transport
-
DOI 10.1074/jbc.273.13.7470
-
Standaert, M. et al. Comparative effects of GTPgammaS and insulin on the activation of Rho, phosphatidylinositol 3-kinase, and protein kinase N in rat adipocytes. Relationship to glucose transport. J. Biol. Chem. 273, 7470-7477 (1998). (Pubitemid 28152770)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.13
, pp. 7470-7477
-
-
Standaert, M.1
Bandyopadhyay, G.2
Galloway, L.3
Ono, Y.4
Mukai, H.5
Farese, R.6
-
34
-
-
47249116180
-
Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy
-
Bossi, G. et al. Conditional RNA interference in vivo to study mutant p53 oncogenic gain of function on tumor malignancy. Cell Cycle 7, 1870-1879 (2008). (Pubitemid 351988754)
-
(2008)
Cell Cycle
, vol.7
, Issue.12
, pp. 1870-1879
-
-
Bossi, G.1
Marampon, F.2
Maor-Aloni, R.3
Zani, B.4
Rotter, V.5
Oren, M.6
Strano, S.7
Blandino, G.8
Sacchi, A.9
-
35
-
-
78951475020
-
P53 and its mutants in tumor cell migration and invasion
-
Muller, P. A., Vousden, K. H. & Norman, J. C. p53 and its mutants in tumor cell migration and invasion. J. Cell Biol. 192, 209-218 (2011).
-
(2011)
J. Cell Biol.
, vol.192
, pp. 209-218
-
-
Muller, P.A.1
Vousden, K.H.2
Norman, J.C.3
-
36
-
-
33745700179
-
Mutant p53 induces the GEF-H1 oncogene, a guanine nucleotide exchange factor-H1 for RhoA, resulting in accelerated cell proliferation in tumor cells
-
Mizuarai, S., Yamanaka, K. & Kotani, H. Mutant p53 induces the GEF-H1 oncogene, a guanine nucleotide exchange factor-H1 for RhoA, resulting in accelerated cell proliferation in tumor cells. Cancer Res. 66, 6319-6326 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 6319-6326
-
-
Mizuarai, S.1
Yamanaka, K.2
Kotani, H.3
-
37
-
-
79551561001
-
Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53
-
Timpson, P. et al. Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53. Cancer Res. 71, 747-757 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 747-757
-
-
Timpson, P.1
-
39
-
-
84859412056
-
Regulation of glucose transport by ROCK1 differs from that of ROCK2 and is controlled by actin polymerization
-
Chun, K. H. et al. Regulation of glucose transport by ROCK1 differs from that of ROCK2 and is controlled by actin polymerization. Endocrinology 153, 1649-1662 (2012).
-
(2012)
Endocrinology
, vol.153
, pp. 1649-1662
-
-
Chun, K.H.1
-
40
-
-
25144500035
-
Role of Rho-kinase in regulation of insulin action and glucose homeostasis
-
Furukawa, N. et al. Role of Rho-kinase in regulation of insulin action and glucose homeostasis. Cell Metab. 2, 119-129 (2005).
-
(2005)
Cell Metab.
, vol.2
, pp. 119-129
-
-
Furukawa, N.1
-
41
-
-
66449126949
-
Targeted disruption of ROCK1 causes insulin resistance in vivo
-
Lee, D. H. et al. Targeted disruption of ROCK1 causes insulin resistance in vivo. J. Biol. Chem. 284, 11776-11780 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 11776-11780
-
-
Lee, D.H.1
-
42
-
-
0034017744
-
Pharmacological properties of Y-27632, a specific inhibitor of Rho- associated kinases
-
Ishizaki, T. et al. Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases. Mol. Pharmacol. 57, 976-983 (2000). (Pubitemid 30253382)
-
(2000)
Molecular Pharmacology
, vol.57
, Issue.5
, pp. 976-983
-
-
Ishizaki, T.1
Uehata, M.2
Tamechika, I.3
Keel, J.4
Nonomura, K.5
Maekawa, M.6
Narumiya, S.7
-
43
-
-
0036632368
-
The phosphatidylinositol 3-kinase-AKT pathway in human cancer
-
Vivanco, I. & Sawyers, C. L. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat. Rev. Cancer 2, 489-501 (2002). (Pubitemid 37328931)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.7
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
44
-
-
34248591612
-
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
-
DOI 10.1038/sj.onc.1210422, PII 1210422
-
Roberts, P. J. & Der, C. J. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 26, 3291-3310 (2007). (Pubitemid 46763022)
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3291-3310
-
-
Roberts, P.J.1
Der, C.J.2
-
45
-
-
75849118878
-
Targeting the PI3K signaling pathway in cancer
-
Wong, K. K., Engelman, J. A. & Cantley, L. C. Targeting the PI3K signaling pathway in cancer. Curr. Opin. Genet. Dev. 20, 87-90 (2010).
-
(2010)
Curr. Opin. Genet. Dev.
, vol.20
, pp. 87-90
-
-
Wong, K.K.1
Engelman, J.A.2
Cantley, L.C.3
-
46
-
-
84880302677
-
Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis
-
Hanel, W. et al. Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis. Cell Death Differ. 20, 898-909 (2013).
-
(2013)
Cell Death Differ.
, vol.20
, pp. 898-909
-
-
Hanel, W.1
-
47
-
-
34848845313
-
Modifying IGF1 activity: An approach to treat endocrine disorders, atherosclerosis and cancer
-
DOI 10.1038/nrd2359, PII NRD2359
-
Clemmons, D. R. Modifying IGF1 activity: an approach to treat endocrine disorders, atherosclerosis and cancer. Nature reviews. Drug Discov. 6, 821-833 (2007). (Pubitemid 47500506)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.10
, pp. 821-833
-
-
Clemmons, D.R.1
-
48
-
-
34547959158
-
Actin in membrane trafficking
-
DOI 10.1016/j.ceb.2007.04.017, PII S0955067407000786
-
Lanzetti, L. Actin in membrane trafficking. Curr. Opin. Cell Biol. 19, 453-458 (2007). (Pubitemid 47268758)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.4
, pp. 453-458
-
-
Lanzetti, L.1
-
49
-
-
0033529620
-
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase
-
DOI 10.1126/science.285.5429.895
-
Maekawa, M. et al. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 285, 895-898 (1999). (Pubitemid 29381991)
-
(1999)
Science
, vol.285
, Issue.5429
, pp. 895-898
-
-
Maekawa, M.1
Ishizaki, T.2
Boku, S.3
Watanabe, N.4
Fujita, A.5
Iwamatsu, A.6
Obinata, T.7
Ohashi, K.8
Mizuno, K.9
Narumiya, S.10
-
50
-
-
0035065418
-
Effects of cytochalasin D and latrunculin B on mechanical properties of cells
-
Wakatsuki, T., Schwab, B., Thompson, N. C. & Elson, E. L. Effects of cytochalasin D and latrunculin B on mechanical properties of cells. J. Cell Sci. 114, 1025-1036 (2001). (Pubitemid 32266272)
-
(2001)
Journal of Cell Science
, vol.114
, Issue.5
, pp. 1025-1036
-
-
Wakatsuki, T.1
Schwab, B.2
Thompson, N.C.3
Elson, E.L.4
-
51
-
-
0023007962
-
Actin polymerization. The mechanism of action of cytochalasin D
-
Goddette, D. W. & Frieden, C. Actin polymerization. The mechanism of action of cytochalasin D. J. Biol. Chem. 261, 15974-15980 (1986). (Pubitemid 17202846)
-
(1986)
Journal of Biological Chemistry
, vol.261
, Issue.34
, pp. 15974-15980
-
-
Goddette, D.W.1
Frieden, C.2
-
52
-
-
79952501323
-
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization
-
Finley, L. W. et al. SIRT3 opposes reprogramming of cancer cell metabolism through HIF1alpha destabilization. Cancer cell 19, 416-428 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 416-428
-
-
Finley, L.W.1
-
53
-
-
77952737658
-
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
-
Weinberg, F. et al. Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity. Proc. Natl Acad. Sci. USA 107, 8788-8793 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 8788-8793
-
-
Weinberg, F.1
-
54
-
-
84862636275
-
Mutant p53: One name, many proteins
-
Freed-Pastor, W. A. & Prives, C. Mutant p53: one name, many proteins. Genes Dev. 26, 1268-1286 (2012).
-
(2012)
Genes Dev.
, vol.26
, pp. 1268-1286
-
-
Freed-Pastor, W.A.1
Prives, C.2
-
55
-
-
36749081541
-
P53 regulates maternal reproduction through LIF
-
DOI 10.1038/nature05993, PII NATURE05993
-
Hu, W., Feng, Z., Teresky, A. K. & Levine, A. J. p53 regulates maternal reproduction through LIF. Nature 450, 721-724 (2007). (Pubitemid 350207678)
-
(2007)
Nature
, vol.450
, Issue.7170
, pp. 721-724
-
-
Hu, W.1
Feng, Z.2
Teresky, A.K.3
Levine, A.J.4
-
56
-
-
33646462136
-
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
-
Haemmerle, G. et al. Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science 312, 734-737 (2006).
-
(2006)
Science
, vol.312
, pp. 734-737
-
-
Haemmerle, G.1
-
57
-
-
36049022385
-
Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice
-
DOI 10.1172/JCI31929
-
Hofmann, S. M. et al. Adipocyte LDL receptor-related protein-1 expression modulates postprandial lipid transport and glucose homeostasis in mice. J. Clin. Invest. 117, 3271-3282 (2007). (Pubitemid 350096984)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.11
, pp. 3271-3282
-
-
Hofmann, S.M.1
Zhou, L.2
Perez-Tilve, D.3
Greer, T.4
Grant, E.5
Wancata, L.6
Thomas, A.7
Pfluger, P.T.8
Basford, J.E.9
Gilham, D.10
Herz, J.11
Tschop, M.H.12
Hui, D.Y.13
-
58
-
-
0025815205
-
Differential regulation of the GLUT-1 and GLUT-4 glucose transport systems by glucose and insulin in L6 muscle cells in culture
-
Koivisto, U. M. et al. Differential regulation of the GLUT-1 and GLUT-4 glucose transport systems by glucose and insulin in L6 muscle cells in culture. J. Biol. Chem. 266, 2615-2621 (1991).
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 2615-2621
-
-
Koivisto, U.M.1
-
59
-
-
74549184087
-
G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin 'outside-in' signaling
-
Gong, H. et al. G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin 'outside-in' signaling. Science 327, 340-343 (2010).
-
(2010)
Science
, vol.327
, pp. 340-343
-
-
Gong, H.1
-
60
-
-
0021016035
-
Insulin-stimulated translocation of glucose transporters in the isolated rat adipose cells: Characterization of subcellular fractions
-
DOI 10.1016/0167-4889(83)90101-5
-
Simpson, I. A. et al. Insulin-stimulated translocation of glucose transporters in the isolated rat adipose cells: characterization of subcellular fractions. Biochim. Biophys. Acta 763, 393-407 (1983). (Pubitemid 14211378)
-
(1983)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.763
, Issue.4
, pp. 393-407
-
-
Simpson, I.A.1
Yver, D.R.2
Hissin, P.J.3
-
61
-
-
9144238702
-
Dehydroepiandrosterone Stimulates Glucose Uptake in Human and Murine Adipocytes by Inducing GLUT1 and GLUT4 Translocation to the Plasma Membrane
-
DOI 10.2337/diabetes.53.1.41
-
Perrini, S. et al. Dehydroepiandrosterone stimulates glucose uptake in human and murine adipocytes by inducing GLUT1 and GLUT4 translocation to the plasma membrane. Diabetes 53, 41-52 (2004). (Pubitemid 38044696)
-
(2004)
Diabetes
, vol.53
, Issue.1
, pp. 41-52
-
-
Perrini, S.1
Natalicchio, A.2
Laviola, L.3
Belsanti, G.4
Montrone, C.5
Cignarelli, A.6
Minielli, V.7
Grano, M.8
De Pergola, G.9
Giorgino, R.10
Giorgino, F.11
-
62
-
-
81055126129
-
Estrogen-related receptor-alpha is a metabolic regulator of effector T-cell activation and differentiation.
-
Michalek, R. D. et al. Estrogen-related receptor-alpha is a metabolic regulator of effector T-cell activation and differentiation. Proc. Natl Acad. Sci. USA 108, 18348-18353 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 18348-18353
-
-
Michalek, R.D.1
-
63
-
-
34247184208
-
Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking
-
DOI 10.1091/mbc.E06-07-0593
-
Wieman, H. L., Wofford, J. A. & Rathmell, J. C. Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking. Mol. Biol. Cell 18, 1437-1446 (2007). (Pubitemid 46626638)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.4
, pp. 1437-1446
-
-
Wieman, H.L.1
Wofford, J.A.2
Rathmell, J.C.3
-
64
-
-
79955683477
-
Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes
-
Miyamoto, K., Pasque, V., Jullien, J. & Gurdon, J. B. Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes. Genes Dev. 25, 946-958.
-
Genes Dev.
, vol.25
, pp. 946-958
-
-
Miyamoto, K.1
Pasque, V.2
Jullien, J.3
Gurdon, J.B.4
-
65
-
-
77953096272
-
Negative regulation of tumor suppressor p53 by microRNA miR-504
-
Hu, W. et al. Negative regulation of tumor suppressor p53 by microRNA miR-504. Mol. Cell 38, 689-699 (2010).
-
(2010)
Mol. Cell
, vol.38
, pp. 689-699
-
-
Hu, W.1
|