XPKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells

Cell

Volumn 155, Issue 2, 2013, Pages 397-

  Israelsen, William J ^a   Dayton, Talya L ^a   Davidson, Shawn M ^a   Fiske, Brian P ^a   Hosios, Aaron M ^a   Bellinger, Gary ^a   Li, Jie ^b   Yu, Yimin ^a   Sasaki, Mika ^c   Horner, James W ^d,k   Burga, Laura N ^c   Xie, Jianxin ^e   Jurczak, Michael J ^f   Depinho, Ronald A ^b,d   Clish, Clary B ^g   Jacks, Tyler ^a   Kibbey, Richard G ^f   Wulf, Gerburg M ^c   Di Vizio, Dolores ^h,i,j   Mills, Gordon B ^b   Cantley, Lewis C ^c,j   Vander Heiden, Matthew G ^a,b   more..

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e CELL SIGNALING TECHNOLOGY   (United States)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^h CEDARS SINAI MEDICAL CENTER   (United States)

ⁱ BOSTON CHILDREN S HOSPITAL   (United States)

^j HARVARD MEDICAL SCHOOL   (United States)

^k UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; GLUCOSE; ISOENZYME; PYRUVATE KINASE; PYRUVATE KINASE M2; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST TUMOR; CANCER CELL; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; EXON; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GLUCOSE METABOLISM; HUMAN; LIVER METASTASIS; MOUSE; NONHUMAN; POPULATION; PRIORITY JOURNAL; TUMOR CELL; TUMOR GROWTH;

MUS;

EID: 84885589840     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2013.09.025     Document Type: Article

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