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Volumn 20, Issue 2, 2001, Pages 147-155

Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53

(9) Bacus, Sarah S a Gudkov, Andrei V b Lowe, Michael c Lyass, Ljuba a Yung, Yuval d Komarov, Andrei P b Keyomarsi, Khandan c Yarden, Yosef d Seger, Rony d

a Quantitative Diagnostics Laboratory (United States)

b UNIVERSITY OF ILLINOIS AT CHICAGO (United States)

c STATE UNIVERSITY OF NEW YORK (United States)

d WEIZMANN INSTITUTE OF SCIENCE (Israel)

Author keywords

Apoptosis; Cell cycle; Her 2; MAP kinase; p53; Taxol

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; MITOGEN ACTIVATED PROTEIN KINASE; PACLITAXEL; PROTEIN P53;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE; CELL SURVIVAL; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ANALYSIS; HUMAN; HUMAN CELL; MITOSIS INHIBITION; ONCOGENE NEU; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BREAST NEOPLASMS; CARCINOMA; CDC2-CDC28 KINASES; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; ENZYME INHIBITORS; FEMALE; FLAVONOIDS; G2 PHASE; HUMANS; IMIDAZOLES; MAP KINASE KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MITOSIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PACLITAXEL; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; RATS; RECEPTOR, ERBB-2; RETINOBLASTOMA PROTEIN; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035843123 PISSN: 09509232 EISSN: None Source Type: Journal
DOI: 10.1038/sj.onc.1204062 Document Type: Article

Times cited : (336)

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