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Volumn 44, Issue 14, 2016, Pages 6505-6517

Transcriptional gene silencing in humans

Author keywords

[No Author keywords available]

Indexed keywords

LONG UNTRANSLATED RNA; SMALL UNTRANSLATED RNA; COMPLEMENTARY RNA;

EID: 84976649938     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkw139     Document Type: Review
Times cited : (78)

References (177)
  • 1
    • 0000213492 scopus 로고
    • Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants
    • Matzke,M.A., Primig,M., Trnovsky,J. and Matzke,A.J.M. (1989) Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants. EMBO J., 8, 643-649.
    • (1989) EMBO J. , vol.8 , pp. 643-649
    • Matzke, M.A.1    Primig, M.2    Trnovsky, J.3    Matzke, A.J.M.4
  • 2
    • 0034596989 scopus 로고    scopus 로고
    • Transcriptional silencing and promoter methylation triggered by double-stranded RNA
    • Mette,M.F., Aufsatz,W., Van der Winden,J., Matzke,A.J.M. and Matzke,M.A. (2000) Transcriptional silencing and promoter methylation triggered by double-stranded RNA. EMBO J., 19, 5194-5201.
    • (2000) EMBO J. , vol.19 , pp. 5194-5201
    • Mette, M.F.1    Aufsatz, W.2    Van Der Winden, J.3    Matzke, A.J.M.4    Matzke, M.A.5
  • 3
    • 0028031830 scopus 로고
    • RNA-directed de novo methylation of genomic sequences in plants
    • Wassenegger,M., Heimes,S., Riedel,L. and Sänger,H.L. (1994) RNA-directed de novo methylation of genomic sequences in plants. Cell, 76, 567-576.
    • (1994) Cell , vol.76 , pp. 567-576
    • Wassenegger, M.1    Heimes, S.2    Riedel, L.3    Sänger, H.L.4
  • 4
    • 4243085624 scopus 로고    scopus 로고
    • Distinct mechanisms determine transposon inheritance and methylation via small interfering RNA and histone modification
    • Lippman,Z., May,B., Yordan,C., Singer,T. and Martienssen,R. (2003) Distinct mechanisms determine transposon inheritance and methylation via small interfering RNA and histone modification. PLoS Biol., 1, E67.
    • (2003) PLoS Biol. , vol.1 , pp. E67
    • Lippman, Z.1    May, B.2    Yordan, C.3    Singer, T.4    Martienssen, R.5
  • 5
    • 0032506226 scopus 로고    scopus 로고
    • Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA
    • Waterhouse,P.M., Graham,M.W. and Wang,M.B. (1998) Virus resistance and gene silencing in plants can be induced by simultaneous expression of sense and antisense RNA. Proc. Natl. Acad. Sci. U.S.A., 95, 13959-13964.
    • (1998) Proc. Natl. Acad. Sci. U.S.A , vol.95 , pp. 13959-13964
    • Waterhouse, P.M.1    Graham, M.W.2    Wang, M.B.3
  • 6
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire,A., Xu,S., Montgomery,M.K., Kostas,S.A., Driver,S.E. and Mello,C.C. (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 391, 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 7
    • 80051862684 scopus 로고    scopus 로고
    • Small RNA-induced transcriptional gene regulation in mammals mechanisms, therapeutic applications, and scope within the genome
    • Green,V.A. and Weinberg,M.S. (2011) Small RNA-induced transcriptional gene regulation in mammals mechanisms, therapeutic applications, and scope within the genome. Prog. Mol. Biol. Transl. Sci., 102, 11-46.
    • (2011) Prog. Mol. Biol. Transl. Sci. , vol.102 , pp. 11-46
    • Green, V.A.1    Weinberg, M.S.2
  • 8
    • 76749108015 scopus 로고    scopus 로고
    • RNA-directed transcriptional gene silencing and activation in human cells
    • Morris,K.V. (2009) RNA-directed transcriptional gene silencing and activation in human cells. Oligonucleotides, 19, 299-306.
    • (2009) Oligonucleotides , vol.19 , pp. 299-306
    • Morris, K.V.1
  • 9
    • 4344705410 scopus 로고    scopus 로고
    • Small interfering RNA-induced transcriptional gene silencing in human cells
    • Morris,K.V., Chan,S.W., Jacobsen,S.E. and Looney,D.J. (2004) Small interfering RNA-induced transcriptional gene silencing in human cells. Science, 305, 1289-1292.
    • (2004) Science , vol.305 , pp. 1289-1292
    • Morris, K.V.1    Chan, S.W.2    Jacobsen, S.E.3    Looney, D.J.4
  • 10
    • 23044507007 scopus 로고    scopus 로고
    • Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation
    • Ting,A.H., Schuebel,K.E., Herman,J.G. and Baylin,S.B. (2005) Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation. Nat. Genet., 37, 906-910.
    • (2005) Nat. Genet. , vol.37 , pp. 906-910
    • Ting, A.H.1    Schuebel, K.E.2    Herman, J.G.3    Baylin, S.B.4
  • 12
    • 40649125588 scopus 로고    scopus 로고
    • RNA-mediated transcriptional gene silencing in human cells
    • Morris,K.V. (2008) RNA-mediated transcriptional gene silencing in human cells. Curr. Top. Microbiol. Immunol., 320, 211-224.
    • (2008) Curr. Top. Microbiol. Immunol. , vol.320 , pp. 211-224
    • Morris, K.V.1
  • 13
    • 29344463071 scopus 로고    scopus 로고
    • SiRNA-mediated transcriptional gene silencing: The potential mechanism and a possible role in the histone code
    • Morris,K.V. (2005) siRNA-mediated transcriptional gene silencing: the potential mechanism and a possible role in the histone code. Cell Mol. Life Sci., 62, 3057-3066.
    • (2005) Cell Mol. Life Sci. , vol.62 , pp. 3057-3066
    • Morris, K.V.1
  • 14
    • 66249108936 scopus 로고    scopus 로고
    • Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells
    • Hawkins,P.G., Santoso,S., Adams,C., Anest,V. and Morris,K.V. (2009) Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells. Nucleic Acids Res., 2984-2995.
    • (2009) Nucleic Acids Res. , pp. 2984-2995
    • Hawkins, P.G.1    Santoso, S.2    Adams, C.3    Anest, V.4    Morris, K.V.5
  • 15
    • 20844435197 scopus 로고    scopus 로고
    • Short hairpin RNA-directed cytosine (CpG) methylation of the RASSF1A gene promoter in HeLa cells
    • Castanotto,D., Tommasi,S., Li,M., Li,H., Yanow,S., Pfeifer,G.P. and Rossi,J.J. (2005) Short hairpin RNA-directed cytosine (CpG) methylation of the RASSF1A gene promoter in HeLa cells. Mol. Ther., 12, 179-183.
    • (2005) Mol. Ther. , vol.12 , pp. 179-183
    • Castanotto, D.1    Tommasi, S.2    Li, M.3    Li, H.4    Yanow, S.5    Pfeifer, G.P.6    Rossi, J.J.7
  • 16
    • 34547626629 scopus 로고    scopus 로고
    • Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells
    • Han,J., Kim,D. and Morris,K.V. (2007) Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells. Proc. Natl. Acad. Sci. U.S.A., 104, 12422-12427.
    • (2007) Proc. Natl. Acad. Sci. U.S.A , vol.104 , pp. 12422-12427
    • Han, J.1    Kim, D.2    Morris, K.V.3
  • 17
    • 33748368912 scopus 로고    scopus 로고
    • Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells
    • Kim,D.H., Villeneuve,L.M.,Morris,K.V. and Rossi,J.J. (2006) Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nat. Struct. Mol. Biol., 13, 793-797.
    • (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 793-797
    • Kim, D.H.1    Villeneuve, L.M.2    Morris, K.V.3    Rossi, J.J.4
  • 18
  • 22
    • 67649537602 scopus 로고    scopus 로고
    • Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells
    • Napoli,S., Pastori,C., Magistri,M., Carbone,G.M. and Catapano,C.V. (2009) Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells. EMBO J., 28, 1708-1719.
    • (2009) EMBO J. , vol.28 , pp. 1708-1719
    • Napoli, S.1    Pastori, C.2    Magistri, M.3    Carbone, G.M.4    Catapano, C.V.5
  • 24
    • 57849109058 scopus 로고    scopus 로고
    • Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters
    • Core,L.J., Waterfall,J.J. and Lis,J.T. (2008) Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters. Science, 322, 1845-1848.
    • (2008) Science , vol.322 , pp. 1845-1848
    • Core, L.J.1    Waterfall, J.J.2    Lis, J.T.3
  • 26
    • 84863229335 scopus 로고    scopus 로고
    • Direct evidence of nuclear Argonaute distribution during transcriptional silencing links the actin cytoskeleton to nuclear RNAi machinery in human cells
    • Ahlenstiel,C.L., Lim,H.G., Cooper,D.A., Ishida,T., Kelleher,A.D. and Suzuki,K. (2012) Direct evidence of nuclear Argonaute distribution during transcriptional silencing links the actin cytoskeleton to nuclear RNAi machinery in human cells. Nucleic Acids Res., 40, 1579-1595.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 1579-1595
    • Ahlenstiel, C.L.1    Lim, H.G.2    Cooper, D.A.3    Ishida, T.4    Kelleher, A.D.5    Suzuki, K.6
  • 27
    • 55849135596 scopus 로고    scopus 로고
    • MicroRNA-directed transcriptional gene silencing in mammalian cells
    • Kim,D.H., Saetrom,P., Snove,O.Jr and Rossi,J.J. (2008) MicroRNA-directed transcriptional gene silencing in mammalian cells. Proc. Natl. Acad. Sci. U.S.A., 105, 16230-16235.
    • (2008) Proc. Natl. Acad. Sci. U.S.A , vol.105 , pp. 16230-16235
    • Kim, D.H.1    Saetrom, P.2    Snove, O.3    Rossi, J.J.4
  • 28
    • 14744297918 scopus 로고    scopus 로고
    • Regulation of human immunodeficiency virus 1 transcription by nef microRNA
    • Omoto,S. and Fujii,Y.R. (2005) Regulation of human immunodeficiency virus 1 transcription by nef microRNA. J. Gen. Virol., 86, 751-755.
    • (2005) J. Gen. Virol. , vol.86 , pp. 751-755
    • Omoto, S.1    Fujii, Y.R.2
  • 29
    • 34548304523 scopus 로고    scopus 로고
    • HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR
    • Klase,Z., Kale,P., Winograd,R., Gupta,M.V., Heydarian,M., Berro,R., McCaffrey,T. and Kashanchi,F. (2007) HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR. BMC Mol. Biol., 8, 63.
    • (2007) BMC Mol. Biol. , vol.8 , pp. 63
    • Klase, Z.1    Kale, P.2    Winograd, R.3    Gupta, M.V.4    Heydarian, M.5    Berro, R.6    McCaffrey, T.7    Kashanchi, F.8
  • 30
    • 65549158866 scopus 로고    scopus 로고
    • Transcriptional inhibition of Hoxd4 expression by noncoding RNAs in human breast cancer cells
    • Tan,Y., Zhang,B., Wu,T., Skogerbo,G., Zhu,X., Guo,X., He,S. and Chen,R. (2009) Transcriptional inhibition of Hoxd4 expression by noncoding RNAs in human breast cancer cells. BMC Mol. Biol., 10, 12.
    • (2009) BMC Mol. Biol. , vol.10 , pp. 12
    • Tan, Y.1    Zhang, B.2    Wu, T.3    Skogerbo, G.4    Zhu, X.5    Guo, X.6    He, S.7    Chen, R.8
  • 33
    • 15544380198 scopus 로고    scopus 로고
    • Naturally occurring antisense: Transcriptional leakage or real overlap
    • Dahary,D., Elroy-Stein,O. and Sorek,R. (2005) Naturally occurring antisense: transcriptional leakage or real overlap? Genome Res., 15, 364-368.
    • (2005) Genome Res , vol.15 , pp. 364-368
    • Dahary, D.1    Elroy-Stein, O.2    Sorek, R.3
  • 35
    • 66349129918 scopus 로고    scopus 로고
    • Regulation of imprinted expression by macro non-coding RNAs
    • Latos,P.A. and Barlow,D.P. (2009) Regulation of imprinted expression by macro non-coding RNAs. RNA Biol., 6, 100-106.
    • (2009) RNA Biol. , vol.6 , pp. 100-106
    • Latos, P.A.1    Barlow, D.P.2
  • 36
    • 77950841042 scopus 로고    scopus 로고
    • Transcriptional gene silencing through epigenetic changes mediated by non-coding RNAs
    • Malecova,B. and Morris,K.V. (2010) Transcriptional gene silencing through epigenetic changes mediated by non-coding RNAs. Curr. Opin. Mol. Ther., 12, 214-222.
    • (2010) Curr. Opin. Mol. Ther. , vol.12 , pp. 214-222
    • Malecova, B.1    Morris, K.V.2
  • 37
    • 79959359296 scopus 로고    scopus 로고
    • Long antisense non-coding RNAs function to direct epigenetic complexes that regulate transcription in human cells
    • Morris,K.V. (2009) Long antisense non-coding RNAs function to direct epigenetic complexes that regulate transcription in human cells. Epigenetics, 4, 296-301.
    • (2009) Epigenetics , vol.4 , pp. 296-301
    • Morris, K.V.1
  • 39
    • 57149110631 scopus 로고    scopus 로고
    • Bidirectional transcription directs both transcriptional gene activation and suppression in human cells
    • Morris,K.V., Santoso,S., Turner,A.M., Pastori,C. and Hawkins,P.G. (2008) Bidirectional transcription directs both transcriptional gene activation and suppression in human cells. PLoS Genet., 4, e1000258.
    • (2008) PLoS Genet , vol.4 , pp. e1000258
    • Morris, K.V.1    Santoso, S.2    Turner, A.M.3    Pastori, C.4    Hawkins, P.G.5
  • 40
    • 0038581890 scopus 로고    scopus 로고
    • Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease
    • Tufarelli,C., Stanley,J.A., Garrick,D., Sharpe,J.A., Ayyub,H., Wood,W.G. and Higgs,D.R. (2003) Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease. Nat. Genet., 34, 157-165.
    • (2003) Nat. Genet , vol.34 , pp. 157-165
    • Tufarelli, C.1    Stanley, J.A.2    Garrick, D.3    Sharpe, J.A.4    Ayyub, H.5    Wood, W.G.6    Higgs, D.R.7
  • 41
    • 84869016176 scopus 로고    scopus 로고
    • Activity-dependent human brain coding/noncoding gene regulatory networks
    • Lipovich,L., Dachet,F., Cai,J., Bagla,S., Balan,K., Jia,H. and Loeb,J.A. (2012) Activity-dependent human brain coding/noncoding gene regulatory networks. Genetics, 192, 1133-1148.
    • (2012) Genetics , vol.192 , pp. 1133-1148
    • Lipovich, L.1    Dachet, F.2    Cai, J.3    Bagla, S.4    Balan, K.5    Jia, H.6    Loeb, J.A.7
  • 44
    • 84865553575 scopus 로고    scopus 로고
    • AS1DHRS4, a head-to-head natural antisense transcript, silences the DHRS4 gene cluster in cis and trans
    • Li,Q., Su,Z., Xu,X., Liu,G., Song,X., Wang,R., Sui,X., Liu,T., Chang,X. and Huang,D. (2012) AS1DHRS4, a head-to-head natural antisense transcript, silences the DHRS4 gene cluster in cis and trans. Proc. Natl. Acad. Sci. U.S.A., 109, 14110-14115.
    • (2012) Proc. Natl. Acad. Sci. U.S.A , vol.109 , pp. 14110-14115
    • Li, Q.1    Su, Z.2    Xu, X.3    Liu, G.4    Song, X.5    Wang, R.6    Sui, X.7    Liu, T.8    Chang, X.9    Huang, D.10
  • 45
    • 79957552432 scopus 로고    scopus 로고
    • Kcnq1ot1: A chromatin regulatory RNA
    • Kanduri,C. (2011) Kcnq1ot1: a chromatin regulatory RNA. Semin. Cell Dev. Biol., 22, 343-350.
    • (2011) Semin. Cell Dev. Biol. , vol.22 , pp. 343-350
    • Kanduri, C.1
  • 46
    • 44349115087 scopus 로고    scopus 로고
    • Kcnq1ot1/Lit1 noncoding RNA mediates transcriptional silencing by targeting to the perinucleolar region
    • Mohammad,F., Pandey,R.R., Nagano,T., Chakalova,L., Mondal,T., Fraser,P. and Kanduri,C. (2008) Kcnq1ot1/Lit1 noncoding RNA mediates transcriptional silencing by targeting to the perinucleolar region. Mol. Cell Biol., 28, 3713-3728.
    • (2008) Mol. Cell Biol. , vol.28 , pp. 3713-3728
    • Mohammad, F.1    Pandey, R.R.2    Nagano, T.3    Chakalova, L.4    Mondal, T.5    Fraser, P.6    Kanduri, C.7
  • 48
    • 84912070710 scopus 로고    scopus 로고
    • The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation
    • Pandey,G.K., Mitra,S., Subhash,S., Hertwig,F., Kanduri,M., Mishra,K., Fransson,S., Ganeshram,A., Mondal,T., Bandaru,S. et al. (2014) The risk-associated long noncoding RNA NBAT-1 controls neuroblastoma progression by regulating cell proliferation and neuronal differentiation. Cancer Cell, 26, 722-737.
    • (2014) Cancer Cell , vol.26 , pp. 722-737
    • Pandey, G.K.1    Mitra, S.2    Subhash, S.3    Hertwig, F.4    Kanduri, M.5    Mishra, K.6    Fransson, S.7    Ganeshram, A.8    Mondal, T.9    Bandaru, S.10
  • 50
    • 33751324105 scopus 로고    scopus 로고
    • Human immunodeficiency virus-Type 1 LTR DNA contains an intrinsic gene producing antisense RNA and protein products
    • Ludwig,L.B., Ambrus,J.L. Jr, Krawczyk,K.A., Sharma,S., Brooks,S., Hsiao,C.B. and Schwartz,S.A. (2006) Human immunodeficiency virus-Type 1 LTR DNA contains an intrinsic gene producing antisense RNA and protein products. Retrovirology, 3, 80.
    • (2006) Retrovirology , vol.3 , pp. 80
    • Ludwig, L.B.1    Ambrus, K.A.2    Krawczyk, L.J.3    Sharma, S.4    Brooks, S.5    Hsiao, C.B.6    Schwartz, S.A.7
  • 51
    • 0023898366 scopus 로고
    • Human immunodeficiency virus may encode a novel protein on the genomic DNA plus strand
    • Miller,R.H. (1988) Human immunodeficiency virus may encode a novel protein on the genomic DNA plus strand. Science, 239, 1420-1422.
    • (1988) Science , vol.239 , pp. 1420-1422
    • Miller, R.H.1
  • 54
    • 79952255050 scopus 로고    scopus 로고
    • Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5
    • Hawkins,P.G. and Morris,K.V. (2010) Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5. Transcription, 1, 165-175.
    • (2010) Transcription , vol.1 , pp. 165-175
    • Hawkins, P.G.1    Morris, K.V.2
  • 55
    • 84869129894 scopus 로고    scopus 로고
    • Long noncoding RNA-mediated maintenance of DNA methylation and transcriptional gene silencing
    • Mohammad,F., Pandey,G.K., Mondal,T., Enroth,S., Redrup,L., Gyllensten,U. and Kanduri,C. (2012) Long noncoding RNA-mediated maintenance of DNA methylation and transcriptional gene silencing. Development, 139, 2792-2803.
    • (2012) Development , vol.139 , pp. 2792-2803
    • Mohammad, F.1    Pandey, G.K.2    Mondal, T.3    Enroth, S.4    Redrup, L.5    Gyllensten, U.6    Kanduri, C.7
  • 56
    • 80052394416 scopus 로고    scopus 로고
    • Noncoding transcripts in sense and antisense orientation regulate the epigenetic state of ribosomal RNA genes
    • Bierhoff,H., Schmitz,K., Maass,F., Ye,J. and Grummt,I. (2010) Noncoding transcripts in sense and antisense orientation regulate the epigenetic state of ribosomal RNA genes. Cold Spring Harb. Symp. Quant. Biol., 75, 357-364.
    • (2010) Cold Spring Harb. Symp. Quant. Biol. , vol.75 , pp. 357-364
    • Bierhoff, H.1    Schmitz, K.2    Maass, F.3    Ye, J.4    Grummt, I.5
  • 58
    • 84938200351 scopus 로고    scopus 로고
    • A long non-coding RNA, LncMyoD, regulates skeletal muscle differentiation by blocking IMP2-mediated mRNA translation
    • Gong,C., Li,Z., Ramanujan,K., Clay,I., Zhang,Y., Lemire-Brachat,S. and Glass,D.J. (2015) A long non-coding RNA, LncMyoD, regulates skeletal muscle differentiation by blocking IMP2-mediated mRNA translation. Dev. Cell, 34, 181-191.
    • (2015) Dev. Cell , vol.34 , pp. 181-191
    • Gong, C.1    Li, Z.2    Ramanujan, K.3    Clay, I.4    Zhang, Y.5    Lemire-Brachat, S.6    Glass, D.J.7
  • 59
    • 84899486799 scopus 로고    scopus 로고
    • The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation
    • Wang,P., Xue,Y., Han,Y., Lin,L., Wu,C., Xu,S., Jiang,Z., Xu,J., Liu,Q. and Cao,X. (2014) The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation. Science, 344, 310-313.
    • (2014) Science , vol.344 , pp. 310-313
    • Wang, P.1    Xue, Y.2    Han, Y.3    Lin, L.4    Wu, C.5    Xu, S.6    Jiang, Z.7    Xu, J.8    Liu, Q.9    Cao, X.10
  • 62
    • 84881503516 scopus 로고    scopus 로고
    • Pseudogene OCT4-pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for miR-145 in hepatocellular carcinoma
    • Wang,L., Guo,Z.Y., Zhang,R., Xin,B., Chen,R., Zhao,J., Wang,T., Wen,W.H., Jia,L.T., Yao,L.B. et al. (2013) Pseudogene OCT4-pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for miR-145 in hepatocellular carcinoma. Carcinogenesis, 34, 1773-1781.
    • (2013) Carcinogenesis , vol.34 , pp. 1773-1781
    • Wang, L.1    Guo, Z.Y.2    Zhang, R.3    Xin, B.4    Chen, R.5    Zhao, J.6    Wang, T.7    Wen, W.H.8    Jia, L.T.9    Yao, L.B.10
  • 63
    • 84876367541 scopus 로고    scopus 로고
    • Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal
    • Wang,Y., Xu,Z., Jiang,J., Xu,C., Kang,J., Xiao,L., Wu,M., Xiong,J., Guo,X. and Liu,H. (2013) Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal. Dev. Cell, 25, 69-80.
    • (2013) Dev. Cell , vol.25 , pp. 69-80
    • Wang, Y.1    Xu, Z.2    Jiang, J.3    Xu, C.4    Kang, J.5    Xiao, L.6    Wu, M.7    Xiong, J.8    Guo, X.9    Liu, H.10
  • 64
    • 77953957633 scopus 로고    scopus 로고
    • A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
    • Poliseno,L., Salmena,L., Zhang,J., Carver,B., Haveman,W.J. and Pandolfi,P.P. (2010) A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature, 465, 1033-1038.
    • (2010) Nature , vol.465 , pp. 1033-1038
    • Poliseno, L.1    Salmena, L.2    Zhang, J.3    Carver, B.4    Haveman, W.J.5    Pandolfi, P.P.6
  • 65
    • 84893210532 scopus 로고    scopus 로고
    • Regulation of alternative splicing by local histone modifications: Potential roles for RNA-guided mechanisms
    • Zhou,H.L., Luo,G., Wise,J.A. and Lou,H. (2014) Regulation of alternative splicing by local histone modifications: potential roles for RNA-guided mechanisms. Nucleic Acids Res., 42, 701-713.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 701-713
    • Zhou, H.L.1    Luo, G.2    Wise, J.A.3    Lou, H.4
  • 66
    • 84911377275 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extract
    • Liu,Y., Luo,F., Xu,Y., Wang,B., Zhao,Y., Xu,W., Shi,L., Lu,X. and Liu,Q. (2015) Epithelial-mesenchymal transition and cancer stem cells, mediated by a long non-coding RNA, HOTAIR, are involved in cell malignant transformation induced by cigarette smoke extract. Toxicol. Appl. Pharmacol., 282, 9-19.
    • (2015) Toxicol. Appl. Pharmacol. , vol.282 , pp. 9-19
    • Liu, Y.1    Luo, F.2    Xu, Y.3    Wang, B.4    Zhao, Y.5    Xu, W.6    Shi, L.7    Lu, X.8    Liu, Q.9
  • 67
    • 84905039941 scopus 로고    scopus 로고
    • Urothelial carcinoma associated 1 is a hypoxia-inducible factor-1alpha-targeted long noncoding RNA that enhances hypoxic bladder cancer cell proliferation, migration, and invasion
    • Xue,M., Li,X., Li,Z. and Chen,W. (2014) Urothelial carcinoma associated 1 is a hypoxia-inducible factor-1alpha-targeted long noncoding RNA that enhances hypoxic bladder cancer cell proliferation, migration, and invasion. Tumour Biol., 35, 6901-6912.
    • (2014) Tumour Biol. , vol.35 , pp. 6901-6912
    • Xue, M.1    Li, X.2    Li, Z.3    Chen, W.4
  • 75
    • 79955468280 scopus 로고    scopus 로고
    • Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene
    • Kotake,Y., Nakagawa,T., Kitagawa,K., Suzuki,S., Liu,N., Kitagawa,M. and Xiong,Y. (2011) Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene. Oncogene, 30, 1956-1962.
    • (2011) Oncogene , vol.30 , pp. 1956-1962
    • Kotake, Y.1    Nakagawa, T.2    Kitagawa, K.3    Suzuki, S.4    Liu, N.5    Kitagawa, M.6    Xiong, Y.7
  • 76
    • 84901004299 scopus 로고    scopus 로고
    • The rise of regulatory RNA
    • Morris,K.V. and Mattick,J.S. (2014) The rise of regulatory RNA. Nat. Rev. Genet., 15, 423-437.
    • (2014) Nat. Rev. Genet , vol.15 , pp. 423-437
    • Morris, K.V.1    Mattick, J.S.2
  • 77
    • 84866889114 scopus 로고    scopus 로고
    • RNA modulation of the human DNA methyltransferase 3A
    • Holz-Schietinger,C. and Reich,N.O. (2012) RNA modulation of the human DNA methyltransferase 3A. Nucleic Acids Res., 40, 8550-8557.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 8550-8557
    • Holz-Schietinger, C.1    Reich, N.O.2
  • 78
    • 78649543210 scopus 로고    scopus 로고
    • Recombinant mammalian DNA methyltransferase activity on model transcriptional gene silencing short RNA-DNA heteroduplex substrates
    • Ross,J.P., Suetake,I., Tajima,S. and Molloy,P.L. (2010) Recombinant mammalian DNA methyltransferase activity on model transcriptional gene silencing short RNA-DNA heteroduplex substrates. Biochem. J., 432, 323-332.
    • (2010) Biochem. J. , vol.432 , pp. 323-332
    • Ross, J.P.1    Suetake, I.2    Tajima, S.3    Molloy, P.L.4
  • 80
    • 84861670544 scopus 로고    scopus 로고
    • Characterization of an HIV-targeted transcriptional gene-silencing RNA in primary cells
    • Turner,A.M., Ackley,A.M., Matrone,M.A. and Morris,K.V. (2012) Characterization of an HIV-targeted transcriptional gene-silencing RNA in primary cells. Hum. Gene Ther., 23, 473-483.
    • (2012) Hum. Gene Ther. , vol.23 , pp. 473-483
    • Turner, A.M.1    Ackley, A.M.2    Matrone, M.A.3    Morris, K.V.4
  • 81
    • 84901041535 scopus 로고    scopus 로고
    • RNA-directed DNA methylation: An epigenetic pathway of increasing complexity
    • Matzke,M.A. and Mosher,R.A. (2014) RNA-directed DNA methylation: an epigenetic pathway of increasing complexity. Nat. Rev. Genet., 15, 394-408.
    • (2014) Nat. Rev. Genet , vol.15 , pp. 394-408
    • Matzke, M.A.1    Mosher, R.A.2
  • 82
    • 36048951040 scopus 로고    scopus 로고
    • Antisense RNA stabilization induces transcriptional gene silencing via histone deacetylation in S
    • Camblong,J., Iglesias,N., Fickentscher,C., Dieppois,G. and Stutz,F. (2007) Antisense RNA stabilization induces transcriptional gene silencing via histone deacetylation in S. cerevisiae. Cell, 131, 706-717.
    • (2007) Cerevisiae. Cell , vol.131 , pp. 706-717
    • Camblong, J.1    Iglesias, N.2    Fickentscher, C.3    Dieppois, G.4    Stutz, F.5
  • 83
    • 67649666831 scopus 로고    scopus 로고
    • Trans-acting antisense RNAs mediate transcriptional gene cosuppression in S.cerevisiae
    • Camblong,J., Beyrouthy,N., Guffanti,E., Schlaepfer,G., Steinmetz,L.M. and Stutz,F. (2009) Trans-acting antisense RNAs mediate transcriptional gene cosuppression in S. cerevisiae. Genes Dev., 23, 1534-1545.
    • (2009) Genes Dev. , vol.23 , pp. 1534-1545
    • Camblong, J.1    Beyrouthy, N.2    Guffanti, E.3    Schlaepfer, G.4    Steinmetz, L.M.5    Stutz, F.6
  • 84
    • 0026704195 scopus 로고
    • Characterization of an endogenous RNA transcript with homology to the antisense strand of the human c-myc gene
    • Celano,P., Berchtold,C.M., Kizer,D.L.,Weeraratna,A., Nelkin,B.D., Baylin,S.B. and Casero,R.A. Jr (1992) Characterization of an endogenous RNA transcript with homology to the antisense strand of the human c-myc gene. J. Biol. Chem., 267, 15092-15096.
    • (1992) J. Biol. Chem. , vol.267 , pp. 15092-15096
    • Celano, P.1    Berchtold, C.M.2    Kizer, D.L.3    Weeraratna, A.4    Nelkin, B.D.5    Baylin, S.B.6    Casero, R.A.7
  • 85
    • 0026526181 scopus 로고
    • An antisense promoter of the murine c-myc gene is localized within intron 2
    • Spicer,D.B. and Sonenshein,G.E. (1992) An antisense promoter of the murine c-myc gene is localized within intron 2. Mol. Cell. Biol., 12, 1324-1329.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1324-1329
    • Spicer, D.B.1    Sonenshein, G.E.2
  • 89
    • 0033753779 scopus 로고    scopus 로고
    • The DNA methyltransferases of mammals
    • Bestor,T.H. (2000) The DNA methyltransferases of mammals. Hum. Mol. Genet., 9, 2395-2402.
    • (2000) Hum. Mol. Genet , vol.9 , pp. 2395-2402
    • Bestor, T.H.1
  • 90
    • 10344250458 scopus 로고    scopus 로고
    • Components of the DNA methylation system of chromatin control are RNA-binding proteins
    • Jeffery,L. and Nakielny,S. (2004) Components of the DNA methylation system of chromatin control are RNA-binding proteins. J. Biol. Chem., 279, 49479-49487.
    • (2004) J. Biol. Chem. , vol.279 , pp. 49479-49487
    • Jeffery, L.1    Nakielny, S.2
  • 91
    • 84924449774 scopus 로고    scopus 로고
    • LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration
    • Wang,L., Zhao,Y., Bao,X., Zhu,X., Kwok,Y.K., Sun,K., Chen,X., Huang,Y., Jauch,R., Esteban,M.A. et al. (2015) LncRNA Dum interacts with Dnmts to regulate Dppa2 expression during myogenic differentiation and muscle regeneration. Cell Res., 25, 335-350.
    • (2015) Cell Res. , vol.25 , pp. 335-350
    • Wang, L.1    Zhao, Y.2    Bao, X.3    Zhu, X.4    Kwok, Y.K.5    Sun, K.6    Chen, X.7    Huang, Y.8    Jauch, R.9    Esteban, M.A.10
  • 92
    • 0038412822 scopus 로고    scopus 로고
    • The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase
    • Fuks,F., Hurd,P.J., Deplus,R. and Kouzarides,T. (2003) The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res., 31, 2305-2312.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 2305-2312
    • Fuks, F.1    Hurd, P.J.2    Deplus, R.3    Kouzarides, T.4
  • 93
    • 0035873225 scopus 로고    scopus 로고
    • Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
    • Fuks,F., Burgers,W.A., Godin,N., Kasai,M. and Kouzarides,T. (2001) Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. EMBO J., 20, 2536-2544.
    • (2001) EMBO J. , vol.20 , pp. 2536-2544
    • Fuks, F.1    Burgers, W.A.2    Godin, N.3    Kasai, M.4    Kouzarides, T.5
  • 95
    • 0016692220 scopus 로고
    • X inactivation, differentiation, and DNA methylation
    • Riggs,A.D. (1975) X inactivation, differentiation, and DNA methylation. Cytogenet. Cell Genet., 14, 9-25.
    • (1975) Cytogenet. Cell Genet , vol.14 , pp. 9-25
    • Riggs, A.D.1
  • 96
    • 79959346470 scopus 로고    scopus 로고
    • Non-coding RNAs, epigenetic memory, and the passage of information to progeny
    • Morris,K.V. (2009) Non-coding RNAs, epigenetic memory, and the passage of information to progeny. RNA Biol., 6, 242-247.
    • (2009) RNA Biol. , vol.6 , pp. 242-247
    • Morris, K.V.1
  • 98
    • 78751580427 scopus 로고    scopus 로고
    • Stable suppression of gene expression by short interfering RNAs targeted to promoter in a mouse embryonal carcinoma stem cell line
    • Esmaeili,F., Bamdad,T. and Ghasemi,S. (2010) Stable suppression of gene expression by short interfering RNAs targeted to promoter in a mouse embryonal carcinoma stem cell line. In Vitro Cell. Dev. Biol. Anim., 46, 834-840.
    • (2010) Vitro Cell. Dev. Biol. Anim. , vol.46 , pp. 834-840
    • Esmaeili, F.1    Bamdad, T.2    Ghasemi, S.3
  • 100
    • 39849098733 scopus 로고    scopus 로고
    • Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro
    • Lim,H.G., Suzuki,K., Cooper,D.A. and Kelleher,A.D. (2008) Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro. Mol. Ther., 16, 565-570.
    • (2008) Mol. Ther. , vol.16 , pp. 565-570
    • Lim, H.G.1    Suzuki, K.2    Cooper, D.A.3    Kelleher, A.D.4
  • 101
    • 84958087384 scopus 로고    scopus 로고
    • RNA-directed epigenetic silencing of periostin inhibits cell motility
    • Lister,N.C., Clemson,M. and Morris,K.V. (2015) RNA-directed epigenetic silencing of periostin inhibits cell motility. R. Soc. Open Sci., 2, 140545.
    • (2015) R. Soc. Open Sci. , vol.2 , pp. 140545
    • Lister, N.C.1    Clemson, M.2    Morris, K.V.3
  • 102
    • 34249930701 scopus 로고    scopus 로고
    • Short hairpin RNA causes the methylation of transforming growth factor-beta receptor II promoter and silencing of the target gene in rat hepatic stellate cells
    • Kim,J.W., Zhang,Y.H., Zern,M.A., Rossi,J.J. and Wu,J. (2007) Short hairpin RNA causes the methylation of transforming growth factor-beta receptor II promoter and silencing of the target gene in rat hepatic stellate cells. Biochem. Biophys. Res. Commun., 359, 292-297.
    • (2007) Biochem. Biophys. Res. Commun. , vol.359 , pp. 292-297
    • Kim, J.W.1    Zhang, Y.H.2    Zern, M.A.3    Rossi, J.J.4    Wu, J.5
  • 103
    • 77956107879 scopus 로고    scopus 로고
    • Effect of chemical modifications on modulation of gene expression by duplex antigene RNAs that are complementary to non-coding transcripts at gene promoters
    • Watts,J.K., Yu,D., Charisse,K., Montaillier,C., Potier,P., Manoharan,M. and Corey,D.R. (2010) Effect of chemical modifications on modulation of gene expression by duplex antigene RNAs that are complementary to non-coding transcripts at gene promoters. Nucleic Acids Res., 38, 5242-5259.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 5242-5259
    • Watts, J.K.1    Yu, D.2    Charisse, K.3    Montaillier, C.4    Potier, P.5    Manoharan, M.6    Corey, D.R.7
  • 104
    • 84868347414 scopus 로고    scopus 로고
    • Chemically modified oligonucleotides modulate an epigenetically varied and transient form of transcription silencing of HIV-1 in human cells
    • Knowling,S.S.K., Turner,A.M., Uhlmann,E., Lehmann,T., Vollmer,J. and Morris,K.V. (2012) Chemically modified oligonucleotides modulate an epigenetically varied and transient form of transcription silencing of HIV-1 in human cells. Mol. Ther. Nucleic Acids, 1, e16.
    • (2012) Mol. Ther. Nucleic Acids , vol.1 , pp. e16
    • Knowling, S.S.K.1    Turner, A.M.2    Uhlmann, E.3    Lehmann, T.4    Vollmer, J.5    Morris, K.V.6
  • 105
    • 84925037469 scopus 로고    scopus 로고
    • Cell-specific RNA aptamer against human CCR5 specifically targets HIV-1 susceptible cells and inhibits HIV-1 infectivity
    • Zhou,J., Satheesan,S., Li,H., Weinberg,M.S., Morris,K.V., Burnett,J.C. and Rossi,J.J. (2015) Cell-specific RNA aptamer against human CCR5 specifically targets HIV-1 susceptible cells and inhibits HIV-1 infectivity. Chem. Biol., 22, 379-390.
    • (2015) Chem. Biol. , vol.22 , pp. 379-390
    • Zhou, J.1    Satheesan, S.2    Li, H.3    Weinberg, M.S.4    Morris, K.V.5    Burnett, J.C.6    Rossi, J.J.7
  • 107
    • 70349239135 scopus 로고    scopus 로고
    • Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: A novel example of epigenetherapy
    • Turunen,M.P., Lehtola,T., Heinonen,S.E., Assefa,G.S., Korpisalo,P., Girnary,R., Glass,C.K., Vaisanen,S. and Yla-Herttuala,S. (2009) Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy. Circ. Res., 105, 604-609.
    • (2009) Circ. Res. , vol.105 , pp. 604-609
    • Turunen, M.P.1    Lehtola, T.2    Heinonen, S.E.3    Assefa, G.S.4    Korpisalo, P.5    Girnary, R.6    Glass, C.K.7    Vaisanen, S.8    Yla-Herttuala, S.9
  • 110
    • 84890852686 scopus 로고    scopus 로고
    • Evolutionary conservation of long noncoding RNAs; Sequence, structure, function
    • Johnsson,P., Lipovich,L., Grander,D. and Morris,K.V. (2013) Evolutionary conservation of long noncoding RNAs; sequence, structure, function. Biochim. Biophys. Acta, 1840, 1063-1071.
    • (2013) Biochim. Biophys. Acta , vol.1840 , pp. 1063-1071
    • Johnsson, P.1    Lipovich, L.2    Grander, D.3    Morris, K.V.4
  • 121
    • 40349094597 scopus 로고    scopus 로고
    • MicroRNA-373 induces expression of genes with complementary promoter sequences
    • Place,R.F., Li,L.C., Pookot,D., Noonan,E.J. and Dahiya,R. (2008) MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc. Natl. Acad. Sci. U.S.A., 105, 1608-1613.
    • (2008) Proc. Natl. Acad. Sci. U.S.A , vol.105 , pp. 1608-1613
    • Place, R.F.1    Li, L.C.2    Pookot, D.3    Noonan, E.J.4    Dahiya, R.5
  • 123
    • 0014690698 scopus 로고
    • Gene regulation for higher cells: A theory
    • Britten,R.J. and Davidson,E.H. (1969) Gene regulation for higher cells: a theory. Science, 165, 349-357.
    • (1969) Science , vol.165 , pp. 349-357
    • Britten, R.J.1    Davidson, E.H.2
  • 124
    • 0015070886 scopus 로고
    • Repetitive and non-repetitive DNA sequences and a speculation on the origins of evolutionary novelty
    • Britten,R.J. and Davidson,E.H. (1971) Repetitive and non-repetitive DNA sequences and a speculation on the origins of evolutionary novelty. Q. Rev. Biol., 66, 111-138.
    • (1971) Q. Rev. Biol. , vol.66 , pp. 111-138
    • Britten, R.J.1    Davidson, E.H.2
  • 125
    • 78649540637 scopus 로고    scopus 로고
    • Induction of DNA methylation and gene silencing by short interfering RNAs in human cells
    • Taira,K. (2006) Induction of DNA methylation and gene silencing by short interfering RNAs in human cells. Nature, 441, 1176.
    • (2006) Nature , vol.441 , pp. 1176
    • Taira, K.1
  • 127
    • 44149126227 scopus 로고    scopus 로고
    • A multifunctional human Argonaute2-specific monoclonal antibody
    • Rudel,S., Flatley,A., Weinmann,L., Kremmer,E. and Meister,G. (2008) A multifunctional human Argonaute2-specific monoclonal antibody. RNA, 14, 1244-1253.
    • (2008) RNA , vol.14 , pp. 1244-1253
    • Rudel, S.1    Flatley, A.2    Weinmann, L.3    Kremmer, E.4    Meister, G.5
  • 130
    • 84907030636 scopus 로고    scopus 로고
    • Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading
    • Gagnon,K.T., Li,L., Janowski,B.A. and Corey,D.R. (2014) Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading. Nat. Protoc., 9, 2045-2060.
    • (2014) Nat. Protoc. , vol.9 , pp. 2045-2060
    • Gagnon, K.T.1    Li, L.2    Janowski, B.A.3    Corey, D.R.4
  • 131
    • 84892544892 scopus 로고    scopus 로고
    • RNAi factors are present and active in human cell nuclei
    • Gagnon,K.T., Li,L., Chu,Y., Janowski,B.A. and Corey,D.R. (2014) RNAi factors are present and active in human cell nuclei. Cell Rep., 6, 211-221.
    • (2014) Cell Rep. , vol.6 , pp. 211-221
    • Gagnon, K.T.1    Li, L.2    Chu, Y.3    Janowski, B.A.4    Corey, D.R.5
  • 133
    • 84865812140 scopus 로고    scopus 로고
    • Genomics. ENCODE project writes eulogy for junk DNA
    • Pennisi,E. (2012) Genomics. ENCODE project writes eulogy for junk DNA. Science, 337, 1159, 1161.
    • (2012) Science , vol.337 , pp. 1159-1161
    • Pennisi, E.1
  • 138
    • 7444260846 scopus 로고    scopus 로고
    • The ENCODE (ENCyclopedia of DNA Elements) Project
    • Consortium,E.P. (2004) The ENCODE (ENCyclopedia Of DNA Elements) Project. Science, 306, 636-640.
    • (2004) Science , vol.306 , pp. 636-640
    • Consortium, E.P.1
  • 139
    • 84861904178 scopus 로고    scopus 로고
    • Genome regulation by long noncoding RNAs
    • Rinn,J.L. and Chang,H.Y. (2012) Genome regulation by long noncoding RNAs. Annu. Rev. Biochem., 81, 145-166.
    • (2012) Annu. Rev. Biochem. , vol.81 , pp. 145-166
    • Rinn, J.L.1    Chang, H.Y.2
  • 141
    • 63649088662 scopus 로고    scopus 로고
    • Mobilization-competent lentiviral vector-mediated sustained transcriptional modulation of HIV-1 expression
    • Turner,A.M., De La Cruz,J. and Morris,K.V. (2009) Mobilization-competent Lentiviral Vector-mediated Sustained Transcriptional Modulation of HIV-1 Expression. Mol. Ther., 17, 360-368.
    • (2009) Mol. Ther. , vol.17 , pp. 360-368
    • Turner, A.M.1    De La Cruz, J.2    Morris, K.V.3
  • 142
    • 77954098792 scopus 로고    scopus 로고
    • Controlling transcription with noncoding RNAs in mammalian cells
    • Turner,A.M. and Morris,K.V. (2010) Controlling transcription with noncoding RNAs in mammalian cells. Biotechniques, 48, ix-xvi.
    • (2010) Biotechniques , vol.48 , pp. ix-xvi
    • Turner, A.M.1    Morris, K.V.2
  • 146
    • 34548155531 scopus 로고    scopus 로고
    • Directing DNA methylation to inhibit gene expression
    • Hoffman,A.R. and Hu,J.F. (2006) Directing DNA methylation to inhibit gene expression. Cell. Mol. Neurobiol., 26, 425-438.
    • (2006) Cell. Mol. Neurobiol. , vol.26 , pp. 425-438
    • Hoffman, A.R.1    Hu, J.F.2
  • 148
    • 4444314502 scopus 로고    scopus 로고
    • Double-stranded siRNA targeted to the huntingtin gene does not induce DNA methylation
    • Park,C.W., Chen,Z., Kren,B.T. and Steer,C.J. (2004) Double-stranded siRNA targeted to the huntingtin gene does not induce DNA methylation. Biochem. Biophys. Res. Commun., 323, 275-280.
    • (2004) Biochem. Biophys. Res. Commun. , vol.323 , pp. 275-280
    • Park, C.W.1    Chen, Z.2    Kren, B.T.3    Steer, C.J.4
  • 149
    • 20844434177 scopus 로고    scopus 로고
    • Transcriptional silencing of nonsense codon-containing immunoglobulin minigenes
    • Buhler,M., Mohn,F., Stalder,L. and Muhlemann,O. (2005) Transcriptional silencing of nonsense codon-containing immunoglobulin minigenes. Mol. Cell, 18, 307-317.
    • (2005) Mol. Cell , vol.18 , pp. 307-317
    • Buhler, M.1    Mohn, F.2    Stalder, L.3    Muhlemann, O.4
  • 150
    • 49749133953 scopus 로고    scopus 로고
    • Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs
    • Gonzalez,S., Pisano,D.G. and Serrano,M. (2008) Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs. Cell Cycle, 7, 2601-2608.
    • (2008) Cell Cycle , vol.7 , pp. 2601-2608
    • Gonzalez, S.1    Pisano, D.G.2    Serrano, M.3
  • 151
    • 34250212156 scopus 로고    scopus 로고
    • The proximal GC-rich region of p16(INK4a) gene promoter plays a role in its transcriptional regulation
    • Wang,X., Feng,Y., Pan,L., Wang,Y., Xu,X., Lu,J. and Huang,B. (2007) The proximal GC-rich region of p16(INK4a) gene promoter plays a role in its transcriptional regulation. Mol. Cell. Biochem., 301, 259-266.
    • (2007) Mol. Cell. Biochem. , vol.301 , pp. 259-266
    • Wang, X.1    Feng, Y.2    Pan, L.3    Wang, Y.4    Xu, X.5    Lu, J.6    Huang, B.7
  • 152
    • 34547095270 scopus 로고    scopus 로고
    • Small interfering RNA directed reversal of urokinase plasminogen activator demethylation inhibits prostate tumor growth and metastasis
    • Pulukuri,S.M. and Rao,J.S. (2007) Small interfering RNA directed reversal of urokinase plasminogen activator demethylation inhibits prostate tumor growth and metastasis. Cancer Res., 67, 6637-6646.
    • (2007) Cancer Res. , vol.67 , pp. 6637-6646
    • Pulukuri, S.M.1    Rao, J.S.2
  • 154
    • 78649874963 scopus 로고    scopus 로고
    • Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter
    • Chu,Y., Yue,X., Younger,S.T., Janowski,B.A. and Corey,D.R. (2010) Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter. Nucleic Acids Res., 38, 7736-7748.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 7736-7748
    • Chu, Y.1    Yue, X.2    Younger, S.T.3    Janowski, B.A.4    Corey, D.R.5
  • 155
    • 84927628063 scopus 로고    scopus 로고
    • AGO2 and SETDB1 cooperate in promoter-targeted transcriptional silencing of the androgen receptor gene
    • Cho,S., Park,J.S. and Kang,Y.K. (2014) AGO2 and SETDB1 cooperate in promoter-targeted transcriptional silencing of the androgen receptor gene. Nucleic Acids Res., 42, 13545-13556.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 13545-13556
    • Cho, S.1    Park, J.S.2    Kang, Y.K.3
  • 156
    • 84880281261 scopus 로고    scopus 로고
    • An algorithm for generating small RNAs capable of epigenetically modulating transcriptional gene silencing and activation in human cells
    • Ackley,A., Lenox,A., Stapleton,K., Knowling,S., Lu,T., Sabir,K.S., Vogt,P.K. and Morris,K.V. (2013) An algorithm for generating small RNAs capable of epigenetically modulating transcriptional gene silencing and activation in human cells. Mol. Ther. Nucleic Acids, 2, e104.
    • (2013) Mol. Ther. Nucleic Acids , vol.2 , pp. e104
    • Ackley, A.1    Lenox, A.2    Stapleton, K.3    Knowling, S.4    Lu, T.5    Sabir, K.S.6    Vogt, P.K.7    Morris, K.V.8
  • 157
    • 84907073094 scopus 로고    scopus 로고
    • Combination of hepatocyte specific delivery and transformation dependent expression of shRNA inducing transcriptional gene silencing of c-Myc promoter in hepatocellular carcinoma cells
    • Zakaria,M.K., Khan,I., Mani,P., Chattopadhyay,P., Sarkar,D.P. and Sinha,S. (2014) Combination of hepatocyte specific delivery and transformation dependent expression of shRNA inducing transcriptional gene silencing of c-Myc promoter in hepatocellular carcinoma cells. BMC Cancer, 14, 582.
    • (2014) BMC Cancer , vol.14 , pp. 582
    • Zakaria, M.K.1    Khan, I.2    Mani, P.3    Chattopadhyay, P.4    Sarkar, D.P.5    Sinha, S.6
  • 161
    • 35148864569 scopus 로고    scopus 로고
    • Vitro c-met inhibition by antisense RNA and plasmid-based RNAi down-modulates migration and invasion of hepatocellular carcinoma cells
    • Salvi,A., Arici,B., Portolani,N., Giulini,S.M., De Petro,G. and Barlati,S. (2007) In vitro c-met inhibition by antisense RNA and plasmid-based RNAi down-modulates migration and invasion of hepatocellular carcinoma cells. Int. J. Oncol., 31, 451-460.
    • (2007) Int. J. Oncol. , vol.31 , pp. 451-460
    • Salvi, A.1    Arici, B.2    Portolani, N.3    Giulini, S.M.4    De Petro, G.5    Barlati, S.6
  • 162
    • 84857377246 scopus 로고    scopus 로고
    • Small RNAs targeting transcription start site induce heparanase silencing through interference with transcription initiation in human cancer cells
    • Jiang,G., Zheng,L., Pu,J., Mei,H., Zhao,J., Huang,K., Zeng,F. and Tong,Q. (2012) Small RNAs targeting transcription start site induce heparanase silencing through interference with transcription initiation in human cancer cells. PLoS One, 7, e31379.
    • (2012) PLoS One , vol.7 , pp. e31379
    • Jiang, G.1    Zheng, L.2    Pu, J.3    Mei, H.4    Zhao, J.5    Huang, K.6    Zeng, F.7    Tong, Q.8
  • 164
    • 65549158866 scopus 로고    scopus 로고
    • Transcriptional inhibition of Hoxd4 expression by miRNA-10a in human breast cancer cells
    • Tan,Y., Zhang,B., Wu,T., Skogerbo,G., Zhu,X., Guo,X., He,S. and Chen,R. (2009) Transcriptional inhibition of Hoxd4 expression by miRNA-10a in human breast cancer cells. BMC Mol. Biol., 10, 12.
    • (2009) BMC Mol. Biol. , vol.10 , pp. 12
    • Tan, Y.1    Zhang, B.2    Wu, T.3    Skogerbo, G.4    Zhu, X.5    Guo, X.6    He, S.7    Chen, R.8
  • 166
    • 27644525713 scopus 로고    scopus 로고
    • Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF
    • Cho,D.H., Thienes,C.P., Mahoney,S.E., Analau,E., Filippova,G.N. and Tapscott,S.J. (2005) Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF. Mol. Cell, 20, 483-489.
    • (2005) Mol. Cell , vol.20 , pp. 483-489
    • Cho, D.H.1    Thienes, C.P.2    Mahoney, S.E.3    Analau, E.4    Filippova, G.N.5    Tapscott, S.J.6
  • 167
    • 27644466623 scopus 로고    scopus 로고
    • Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection
    • Wang,Q.Y., Zhou,C., Johnson,K.E., Colgrove,R.C., Coen,D.M. and Knipe,D.M. (2005) Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection. Proc. Natl. Acad. Sci. U.S.A., 102, 16055-16059.
    • (2005) Proc. Natl. Acad. Sci. U.S.A , vol.102 , pp. 16055-16059
    • Wang, Q.Y.1    Zhou, C.2    Johnson, K.E.3    Colgrove, R.C.4    Coen, D.M.5    Knipe, D.M.6
  • 168
    • 77955757309 scopus 로고    scopus 로고
    • Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1
    • Mohammad,F., Mondal,T., Guseva,N., Pandey,G.K. and Kanduri,C. (2010) Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1. Development, 137, 2493-2499.
    • (2010) Development , vol.137 , pp. 2493-2499
    • Mohammad, F.1    Mondal, T.2    Guseva, N.3    Pandey, G.K.4    Kanduri, C.5
  • 170
    • 36949088975 scopus 로고
    • An unstable intermediate carrying information from genes to ribosomes for protein synthesis
    • Brenner,S., Jacob,F. and Meselson,M. (1961) An unstable intermediate carrying information from genes to ribosomes for protein synthesis. Nature, 190, 576-581.
    • (1961) Nature , vol.190 , pp. 576-581
    • Brenner, S.1    Jacob, F.2    Meselson, M.3
  • 171
    • 0344622123 scopus 로고
    • Spliced segments at the 5 terminus of adenovirus 2 late mRNA
    • Berget,S.M., Moore,C. and Sharp,P.A. (1977) Spliced segments at the 5 terminus of adenovirus 2 late mRNA. Proc. Natl. Acad. Sci. U.S.A., 74, 3171-3175.
    • (1977) Proc. Natl. Acad. Sci. U.S.A , vol.74 , pp. 3171-3175
    • Berget, S.M.1    Moore, C.2    Sharp, P.A.3
  • 172
    • 0017688583 scopus 로고
    • An amazing sequence arrangement at the 5 ends of adenovirus 2 messenger RNA
    • Chow,L.T., Gelinas,R.E., Broker,T.R. and Roberts,R.J. (1977) An amazing sequence arrangement at the 5 ends of adenovirus 2 messenger RNA. Cell, 12, 1-8.
    • (1977) Cell , vol.12 , pp. 1-8
    • Chow, L.T.1    Gelinas, R.E.2    Broker, T.R.3    Roberts, R.J.4
  • 174
    • 0026489906 scopus 로고
    • The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus
    • Brockdorff,N., Ashworth,A., Kay,G.F., McCabe,V.M., Norris,D.P., Cooper,P.J., Swift,S. and Rastan,S. (1992) The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell, 71, 515-526.
    • (1992) Cell , vol.71 , pp. 515-526
    • Brockdorff, N.1    Ashworth, A.2    Kay, G.F.3    McCabe, V.M.4    Norris, D.P.5    Cooper, P.J.6    Swift, S.7    Rastan, S.8
  • 175
    • 0027751663 scopus 로고
    • The C.elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee,R.C., Feinbaum,R.L. and Ambros,V. (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell, 75, 843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 176
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C.elegans
    • Wightman,B., Ha,I. and Ruvkun,G. (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell, 75, 855-862.
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 177
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double stranded RNA in Caenorhabditis elegans
    • Fire,A., Xu,S., Montgomery,M.K., Kostas,S.A., Driver,S.E. and Mello,C.C. (1998) Potent and specific genetic interference by double stranded RNA in Caenorhabditis elegans. Nature, 391, 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.