Epigenetic upregulation of endogenous VEGF-A reduces myocardial infarct size in mice

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Turunen, Mikko P ^a   Husso, Tiia ^a   Musthafa, Haja ^a   Laidinen, Svetlana ^a   Dragneva, Galina ^a   Laham Karam, Nihay ^a   Honkanen, Sanna ^a   Paakinaho, Anne ^a   Laakkonen, Johanna P ^a   Gao, Erhe ^b   Vihinen Ranta, Maija ^c   Liimatainen, Timo ^a   Ylä Herttuala, Seppo ^a,d  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF JYVÄSKYLÄ   (Finland)

^d KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; LENTIVIRUS VECTOR; MESSENGER RNA; SHORT HAIRPIN RNA; VASCULOTROPIN A;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; EPIGENETHERAPY; EPIGENETICS; GENE ACTIVITY; GENE CONTROL; GENE EXPRESSION REGULATION; GENE THERAPY; HEART INFARCTION; HEART INFARCTION SIZE; HISTOPATHOLOGY; IN VIVO STUDY; MALE; MOUSE; MULTIPHOTON MICROSCOPY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PROMOTER REGION; PROTEIN EXPRESSION; RNA STRUCTURE; UPREGULATION; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BASE SEQUENCE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA METHYLATION; EPIGENESIS, GENETIC; GENE SILENCING; INVERTED REPEAT SEQUENCES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; PHOSPHOPROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN ISOFORMS; RNA, SMALL INTERFERING; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84896354119     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089979     Document Type: Article

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