-
1
-
-
20144387454
-
Lhermitte-Duclos disease: A report of 31 cases with immunohistochemical analysis of the PTEN/AKT/mTOR pathway
-
Abel, T. W., Baker, S. J., Fraser, M. M., Tihan, T., Nelson, J. S., Yachnis, A. T., et al. (2005). Lhermitte-Duclos disease: a report of 31 cases with immunohistochemical analysis of the PTEN/AKT/mTOR pathway. J. Neuropathol. Exp. Neurol. 64, 341-349. doi: 10.1093/jnen/64.4.341
-
(2005)
J. Neuropathol. Exp. Neurol
, vol.64
, pp. 341-349
-
-
Abel, T.W.1
Baker, S.J.2
Fraser, M.M.3
Tihan, T.4
Nelson, J.S.5
Yachnis, A.T.6
-
2
-
-
84944516901
-
MTORC1 and mTORC2 have largely distinct functions in Purkinje cells
-
Angliker, N., Burri, M., Zaichuk, M., Fritschy, J. M., and Ruegg, M. A. (2015). mTORC1 and mTORC2 have largely distinct functions in Purkinje cells. Eur. J. Neurosci. 42, 2595-2612. doi: 10.1111/ejn.13051
-
(2015)
Eur. J. Neurosci
, vol.42
, pp. 2595-2612
-
-
Angliker, N.1
Burri, M.2
Zaichuk, M.3
Fritschy, J.M.4
Ruegg, M.A.5
-
3
-
-
84937552033
-
Structural components of synaptic plasticity and memory consolidation
-
Bailey, C. H., Kandel, E. R., and Harris, K. M. (2015). Structural components of synaptic plasticity and memory consolidation. Cold Spring Harb. Perspect. Biol. 7:a021758. doi: 10.1101/cshperspect.a021758
-
(2015)
Cold Spring Harb. Perspect. Biol
, vol.7
-
-
Bailey, C.H.1
Kandel, E.R.2
Harris, K.M.3
-
4
-
-
67651055363
-
Establishment of axon-dendrite polarity in developing neurons
-
Barnes, A. P., and Polleux, F. (2009). Establishment of axon-dendrite polarity in developing neurons. Annu. Rev. Neurosci. 32, 347-381. doi: 10.1146/annurev.neuro.31.060407.125536
-
(2009)
Annu. Rev. Neurosci
, vol.32
, pp. 347-381
-
-
Barnes, A.P.1
Polleux, F.2
-
5
-
-
84897840044
-
Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination
-
Bercury, K. K., Dai, J., Sachs, H. H., Ahrendsen, J. T., Wood, T. L., and Macklin, W. B. (2014). Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination. J. Neurosci. 34, 4466-4480. doi: 10.1523/JNEUROSCI.4314-13.2014
-
(2014)
J. Neurosci
, vol.34
, pp. 4466-4480
-
-
Bercury, K.K.1
Dai, J.2
Sachs, H.H.3
Ahrendsen, J.T.4
Wood, T.L.5
Macklin, W.B.6
-
6
-
-
84923226782
-
Dynamics and mechanisms of CNS myelination
-
Bercury, K. K., and Macklin, W. B. (2015). Dynamics and mechanisms of CNS myelination. Dev. Cell 32, 447-458. doi: 10.1016/j.devcel.2015.01.016
-
(2015)
Dev. Cell
, vol.32
, pp. 447-458
-
-
Bercury, K.K.1
Macklin, W.B.2
-
7
-
-
84897535590
-
MTOR signaling contributes to motor skill learning in mice
-
Bergeron, Y., Chagniel, L., Bureau, G., Massicotte, G., and Cyr, M. (2014). mTOR signaling contributes to motor skill learning in mice. Front. Mol. Neurosci. 7:26. doi: 10.3389/fnmol.2014.00026
-
(2014)
Front. Mol. Neurosci
, vol.7
, pp. 26
-
-
Bergeron, Y.1
Chagniel, L.2
Bureau, G.3
Massicotte, G.4
Cyr, M.5
-
8
-
-
72649091698
-
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
-
Bjedov, I., Toivonen, J. M., Kerr, F., Slack, C., Jacobson, J., Foley, A., et al. (2010). Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. Cell Metab. 11, 35-46. doi: 10.1016/j.cmet.2009.11.010
-
(2010)
Cell Metab
, vol.11
, pp. 35-46
-
-
Bjedov, I.1
Toivonen, J.M.2
Kerr, F.3
Slack, C.4
Jacobson, J.5
Foley, A.6
-
9
-
-
84939223134
-
MTOR in brain physiology and pathologies
-
Bockaert, J., and Marin, P. (2015). mTOR in brain physiology and pathologies. Physiol. Rev. 95, 1157-1187. doi: 10.1152/physrev.00038.2014
-
(2015)
Physiol. Rev
, vol.95
, pp. 1157-1187
-
-
Bockaert, J.1
Marin, P.2
-
10
-
-
84900986808
-
Estrogen regulates protein synthesis and actin polymerization in Hippocampal neurons through different molecular mechanisms
-
Briz, V., and Baudry, M. (2014). Estrogen regulates protein synthesis and actin polymerization in Hippocampal neurons through different molecular mechanisms. Front. Endocrinol. (Lausanne) 5:22. doi: 10.3389/fendo.2014.00022
-
(2014)
Front. Endocrinol. (Lausanne)
, vol.5
, pp. 22
-
-
Briz, V.1
Baudry, M.2
-
11
-
-
84936948939
-
Physical biology of human brain development
-
Budday, S., Steinmann, P., and Kuhl, E. (2015). Physical biology of human brain development. Front. Cell. Neurosci. 9:257. doi: 10.3389/fncel.2015.00257
-
(2015)
Front. Cell. Neurosci
, vol.9
, pp. 257
-
-
Budday, S.1
Steinmann, P.2
Kuhl, E.3
-
12
-
-
84923369865
-
NMDA receptor activation regulates sociability by its effect on mTOR signaling activity
-
Burket, J. A., Benson, A. D., Tang, A. H., and Deutsch, S. I. (2015). NMDA receptor activation regulates sociability by its effect on mTOR signaling activity. Prog. Neuropsychopharmacol. Biol. Psychiatry 60, 60-65. doi: 10.1016/j.pnpbp.2015.02.009
-
(2015)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.60
, pp. 60-65
-
-
Burket, J.A.1
Benson, A.D.2
Tang, A.H.3
Deutsch, S.I.4
-
13
-
-
84978955176
-
Building a terminal: Mechanisms of presynaptic development in the CNS
-
Epub ahead of print
-
Bury, L. A., and Sabo, S. L. (2015). Building a terminal: mechanisms of presynaptic development in the CNS. Neuroscientist. doi: 10.1177/1073858415596131 [Epub ahead of print]
-
(2015)
Neuroscientist
-
-
Bury, L.A.1
Sabo, S.L.2
-
14
-
-
84862694395
-
Early events in axon/dendrite polarization
-
Cheng, P. L., and Poo, M. M. (2012). Early events in axon/dendrite polarization. Annu. Rev. Neurosci. 35, 181-201. doi: 10.1146/annurev-neuro-061010-113618
-
(2012)
Annu. Rev. Neurosci
, vol.35
, pp. 181-201
-
-
Cheng, P.L.1
Poo, M.M.2
-
15
-
-
84877124104
-
Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis
-
Cloetta, D., Thomanetz, V., Baranek, C., Lustenberger, R. M., Lin, S., Oliveri, F., et al. (2013). Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis. J. Neurosci. 33, 7799-7810.doi: 10.1523/JNEUROSCI.3294-12.2013
-
(2013)
J. Neurosci
, vol.33
, pp. 7799-7810
-
-
Cloetta, D.1
Thomanetz, V.2
Baranek, C.3
Lustenberger, R.M.4
Lin, S.5
Oliveri, F.6
-
16
-
-
84877927481
-
MTOR in aging, metabolism, and cancer
-
Cornu, M., Albert, V., and Hall, M. N. (2013). mTOR in aging, metabolism, and cancer. Curr. Opin. Genet. Dev. 23, 53-62. doi: 10.1016/j.gde.2012.12.005
-
(2013)
Curr. Opin. Genet. Dev
, vol.23
, pp. 53-62
-
-
Cornu, M.1
Albert, V.2
Hall, M.N.3
-
17
-
-
84855958205
-
MTOR: A pathogenic signaling pathway in developmental brain malformations
-
Crino, P. B. (2011). mTOR: a pathogenic signaling pathway in developmental brain malformations. Trends Mol. Med. 17, 734-742. doi: 10.1016/j.molmed.2011.07.008
-
(2011)
Trends Mol. Med
, vol.17
, pp. 734-742
-
-
Crino, P.B.1
-
18
-
-
56349168452
-
Autophagy and aging: Keeping that old broom working
-
Cuervo, A. M. (2008). Autophagy and aging: keeping that old broom working. Trends Genet. 24, 604-612. doi: 10.1016/j.tig.2008.10.002
-
(2008)
Trends Genet
, vol.24
, pp. 604-612
-
-
Cuervo, A.M.1
-
19
-
-
84930884119
-
MTORC2/rictor signaling disrupts dopamine-dependent behaviors via defects in striatal dopamine neurotransmission
-
Dadalko, O. I., Siuta, M., Poe, A., Erreger, K., Matthies, H. J., Niswender, K., et al. (2015). mTORC2/rictor signaling disrupts dopamine-dependent behaviors via defects in striatal dopamine neurotransmission. J. Neurosci. 35, 8843-8854. doi: 10.1523/JNEUROSCI.0887-15.2015
-
(2015)
J. Neurosci
, vol.35
, pp. 8843-8854
-
-
Dadalko, O.I.1
Siuta, M.2
Poe, A.3
Erreger, K.4
Matthies, H.J.5
Niswender, K.6
-
20
-
-
84940703527
-
Autophagy involving age-related cognitive behavior and hippocampus injury is modulated by different caloric intake in mice
-
Dong, W., Wang, R., Ma, L. N., Xu, B. L., Zhang, J. S., Zhao, Z. W., et al. (2015a). Autophagy involving age-related cognitive behavior and hippocampus injury is modulated by different caloric intake in mice. Int. J. Clin. Exp. Med. 8, 11843-11853
-
(2015)
Int. J. Clin. Exp. Med
, vol.8
, pp. 11843-11853
-
-
Dong, W.1
Wang, R.2
Ma, L.N.3
Xu, B.L.4
Zhang, J.S.5
Zhao, Z.W.6
-
21
-
-
84961211387
-
Influence of age-related learning and memory capacity of Mice: Different effects of a high and low caloric diet
-
Dong, W., Wang, R., Ma, L. N., Xu, B. L., Zhang, J. S., Zhao, Z. W., et al. (2015b). Influence of age-related learning and memory capacity of mice: different effects of a high and low caloric diet. Aging Clin. Exp. Res. 28, 303-311. doi: 10.1007/s40520-015-0398-0
-
(2015)
Aging Clin. Exp. Res
, vol.28
, pp. 303-311
-
-
Dong, W.1
Wang, R.2
Ma, L.N.3
Xu, B.L.4
Zhang, J.S.5
Zhao, Z.W.6
-
22
-
-
84929179463
-
Ribosomal protein S6 kinase 1 signaling in prefrontal cortex controls depressive behavior
-
Dwyer, J. M., Maldonado-Aviles, J. G., Lepack, A. E., DiLeone, R. J., and Duman, R. S. (2015). Ribosomal protein S6 kinase 1 signaling in prefrontal cortex controls depressive behavior. Proc. Natl. Acad. Sci. U.S.A. 112, 6188-6193. doi: 10.1073/pnas.1505289112
-
(2015)
Proc. Natl. Acad. Sci. U.S.A
, vol.112
, pp. 6188-6193
-
-
Dwyer, J.M.1
Maldonado-Aviles, J.G.2
Lepack, A.E.3
Dileone, R.J.4
Duman, R.S.5
-
23
-
-
84888137923
-
Mechanisms of brain morphogenesis
-
eds G. A. Holzapfel and E. Kuhl (Netherlands: Springer
-
Filas, B. A., Xu, G., and Taber, L. A. (2013). “Mechanisms of brain morphogenesis,” in Computer Models in Biomechanics, eds G. A. Holzapfel and E. Kuhl (Netherlands: Springer), 337-349.
-
(2013)
In Computer Models in Biomechanics
, pp. 337-349
-
-
Filas, B.A.1
Xu, G.2
Taber, L.A.3
-
24
-
-
74749106584
-
Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube
-
Fishwick, K. J., Li, R. A., Halley, P., Deng, P., and Storey, K. G. (2010). Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube. Dev. Biol. 338, 215-225. doi: 10.1016/j.ydbio.2009.12.001
-
(2010)
Dev. Biol
, vol.338
, pp. 215-225
-
-
Fishwick, K.J.1
Li, R.A.2
Halley, P.3
Deng, P.4
Storey, K.G.5
-
25
-
-
84875154348
-
Estradiol-induced object recognition memory consolidation is dependent on activation of mTOR signaling in the dorsal hippocampus
-
Fortress, A. M., Fan, L., Orr, P. T., Zhao, Z., and Frick, K. M. (2013). Estradiol-induced object recognition memory consolidation is dependent on activation of mTOR signaling in the dorsal hippocampus. Learn. Mem. 20, 147-155. doi: 10.1101/lm.026732.112
-
(2013)
Learn. Mem
, vol.20
, pp. 147-155
-
-
Fortress, A.M.1
Fan, L.2
Orr, P.T.3
Zhao, Z.4
Frick, K.M.5
-
26
-
-
84864917404
-
GABAergic interneuron development and function is modulated by the Tsc1 gene
-
Fu, C., Cawthon, B., Clinkscales, W., Bruce, A., Winzenburger, P., and Ess, K. C. (2012). GABAergic interneuron development and function is modulated by the Tsc1 gene. Cereb. Cortex 22, 2111-2119. doi: 10.1093/cercor/bhr300
-
(2012)
Cereb. Cortex
, vol.22
, pp. 2111-2119
-
-
Fu, C.1
Cawthon, B.2
Clinkscales, W.3
Bruce, A.4
Winzenburger, P.5
Ess, K.C.6
-
27
-
-
84866340221
-
Consolidation and translation regulation
-
Gal-Ben-Ari, S., Kenney, J. W., Ounalla-Saad, H., Taha, E., David, O., Levitan, D., et al. (2012). Consolidation and translation regulation. Learn. Mem. 19, 410-422. doi: 10.1101/lm.026849.112
-
(2012)
Learn. Mem
, vol.19
, pp. 410-422
-
-
Gal-Ben-Ari, S.1
Kenney, J.W.2
Ounalla-Saad, H.3
Taha, E.4
David, O.5
Levitan, D.6
-
28
-
-
84899099870
-
SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling
-
Garcia-Rodriguez, J. L., Barbier-Torres, L., Fernandez-Alvarez, S., Gutierrez-de Juan, V., Monte, M. J., Halilbasic, E., et al. (2014). SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling. Hepatology 59, 1972-1983. doi: 10.1002/hep.26971
-
(2014)
Hepatology
, vol.59
, pp. 1972-1983
-
-
Garcia-Rodriguez, J.L.1
Barbier-Torres, L.2
Fernandez-Alvarez, S.3
Gutierrez-De Juan, V.4
Monte, M.J.5
Halilbasic, E.6
-
29
-
-
78751705944
-
TOR on the brain
-
Garelick, M. G., and Kennedy, B. K. (2011). TOR on the brain. Exp. Gerontol. 46, 155-163. doi: 10.1016/j.exger.2010.08.030
-
(2011)
Exp. Gerontol
, vol.46
, pp. 155-163
-
-
Garelick, M.G.1
Kennedy, B.K.2
-
30
-
-
84861049888
-
Plasticity and mTOR: Towards restoration of impaired synaptic plasticity in mTOR-related neurogenetic disorders
-
2012
-
Gipson, T. T., and Johnston, M. V. (2012). Plasticity and mTOR: towards restoration of impaired synaptic plasticity in mTOR-related neurogenetic disorders. Neural Plast. 2012:486402. doi: 10.1155/2012/486402
-
(2012)
Neural Plast
-
-
Gipson, T.T.1
Johnston, M.V.2
-
31
-
-
84878268861
-
Gene silencing and Polycomb group proteins: An overview of their structure, mechanisms and phylogenetics
-
Golbabapour, S., Majid, N. A., Hassandarvish, P., Hajrezaie, M., Abdulla, M. A., and Hadi, A. H. (2013). Gene silencing and Polycomb group proteins: an overview of their structure, mechanisms and phylogenetics. OMICS 17, 283-296. doi: 10.1089/omi.2012.0105
-
(2013)
OMICS
, vol.17
, pp. 283-296
-
-
Golbabapour, S.1
Majid, N.A.2
Hassandarvish, P.3
Hajrezaie, M.4
Abdulla, M.A.5
Hadi, A.H.6
-
32
-
-
84999905115
-
Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (MTOR) pathways
-
Gómez, O., Sanchez-Rodriguez, A., Le, M., Sanchez-Caro, C., Molina-Holgado, F., and Molina-Holgado, E. (2011). Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways. Br. J. Pharmacol. 163, 1520-1532. doi: 10.1111/j.1476-5381.2011.01414.x
-
(2011)
Br. J. Pharmacol
, vol.163
, pp. 1520-1532
-
-
Gómez, O.1
Sanchez-Rodriguez, A.2
Le, M.3
Sanchez-Caro, C.4
Molina-Holgado, F.5
Molina-Holgado, E.6
-
33
-
-
84937902216
-
Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brain
-
Gong, H., Qian, H., Ertl, R., Astle, C. M., Wang, G. G., Harrison, D. E., et al. (2015). Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brain. Oncotarget 6, 15882-15890. doi: 10.18632/oncotarget.4137
-
(2015)
Oncotarget
, vol.6
, pp. 15882-15890
-
-
Gong, H.1
Qian, H.2
Ertl, R.3
Astle, C.M.4
Wang, G.G.5
Harrison, D.E.6
-
34
-
-
80052645243
-
Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling
-
Guo, W., Qian, L., Zhang, J., Zhang, W., Morrison, A., Hayes, P., et al. (2011). Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling. J. Neurosci. Res. 89, 1723-1736. doi: 10.1002/jnr.22725
-
(2011)
J. Neurosci. Res
, vol.89
, pp. 1723-1736
-
-
Guo, W.1
Qian, L.2
Zhang, J.3
Zhang, W.4
Morrison, A.5
Hayes, P.6
-
35
-
-
84904910788
-
Acute systemic rapamycin induces neurobehavioral alterations in rats
-
Hadamitzky, M., Herring, A., Keyvani, K., Doenlen, R., Krugel, U., Bosche, K., et al. (2014). Acute systemic rapamycin induces neurobehavioral alterations in rats. Behav. Brain Res. 273, 16-22. doi: 10.1016/j.bbr.2014.06.056
-
(2014)
Behav. Brain Res
, vol.273
, pp. 16-22
-
-
Hadamitzky, M.1
Herring, A.2
Keyvani, K.3
Doenlen, R.4
Krugel, U.5
Bosche, K.6
-
37
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison, D. E., Strong, R., Sharp, Z. D., Nelson, J. F., Astle, C. M., Flurkey, K., et al. (2009). Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 460, 392-395. doi: 10.1038/nature08221
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle, C.M.5
Flurkey, K.6
-
38
-
-
84887017909
-
MTORC1 targets the translational repressor 4E-BP2, but not S6 kinase 1/2, to regulate neural stem cell self-renewal in vivo
-
Hartman, N. W., Lin, T. V., Zhang, L., Paquelet, G. E., Feliciano, D. M., and Bordey, A. (2013). mTORC1 targets the translational repressor 4E-BP2, but not S6 kinase 1/2, to regulate neural stem cell self-renewal in vivo. Cell Rep. 5, 433-444. doi: 10.1016/j.celrep.2013.09.017
-
(2013)
Cell Rep
, vol.5
, pp. 433-444
-
-
Hartman, N.W.1
Lin, T.V.2
Zhang, L.3
Paquelet, G.E.4
Feliciano, D.M.5
Bordey, A.6
-
39
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay, N., and Sonenberg, N. (2004). Upstream and downstream of mTOR. Genes Dev. 18, 1926-1945. doi: 10.1101/gad.1212704
-
(2004)
Genes Dev
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
40
-
-
84893662851
-
Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neurons
-
Heise, C., Gardoni, F., Culotta, L., di Luca, M., Verpelli, C., and Sala, C. (2014). Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neurons. Front. Cell. Neurosci. 8:35. doi: 10.3389/fncel.2014.00035
-
(2014)
Front. Cell. Neurosci
, vol.8
, pp. 35
-
-
Heise, C.1
Gardoni, F.2
Culotta, L.3
Di Luca, M.4
Verpelli, C.5
Sala, C.6
-
41
-
-
77952678006
-
Epigenetic control of neural precursor cell fate during development
-
Hirabayashi, Y., and Gotoh, Y. (2010). Epigenetic control of neural precursor cell fate during development. Nat. Rev. Neurosci. 11, 377-388. doi: 10.1038/nrn2810
-
(2010)
Nat. Rev. Neurosci
, vol.11
, pp. 377-388
-
-
Hirabayashi, Y.1
Gotoh, Y.2
-
42
-
-
33847038824
-
The growing role of mTOR in neuronal development and plasticity
-
Jaworski, J., and Sheng, M. (2006). The growing role of mTOR in neuronal development and plasticity. Mol. Neurobiol. 34, 205-219. doi: 10.1385/MN:34:3:205
-
(2006)
Mol. Neurobiol
, vol.34
, pp. 205-219
-
-
Jaworski, J.1
Sheng, M.2
-
43
-
-
84907882606
-
Melatonin regulates aging and neurodegeneration through energy metabolism, epigenetics, autophagy and circadian rhythm pathways
-
Jenwitheesuk, A., Nopparat, C., Mukda, S., Wongchitrat, P., and Govitrapong, P. (2014). Melatonin regulates aging and neurodegeneration through energy metabolism, epigenetics, autophagy and circadian rhythm pathways. Int. J. Mol. Sci. 15, 16848-16884. doi: 10.3390/ijms150916848
-
(2014)
Int. J. Mol. Sci
, vol.15
, pp. 16848-16884
-
-
Jenwitheesuk, A.1
Nopparat, C.2
Mukda, S.3
Wongchitrat, P.4
Govitrapong, P.5
-
44
-
-
84938149923
-
Cellular and molecular introduction to brain development
-
Jiang, X., and Nardelli, J. (2015). Cellular and molecular introduction to brain development. Neurobiol. Dis. 92, 3-17. doi: 10.1016/j.nbd.2015.07.007
-
(2015)
Neurobiol. Dis
, vol.92
, pp. 3-17
-
-
Jiang, X.1
Nardelli, J.2
-
45
-
-
84155186458
-
Inhibition of mTOR by rapamycin in the amygdala or hippocampus impairs formation and reconsolidation of inhibitory avoidance memory
-
Jobim, P. F., Pedroso, T. R., Christoff, R. R., Werenicz, A., Maurmann, N., Reolon, G. K., et al. (2012a). Inhibition of mTOR by rapamycin in the amygdala or hippocampus impairs formation and reconsolidation of inhibitory avoidance memory. Neurobiol. Learn. Mem. 97, 105-112. doi: 10.1016/j.nlm.2011.10.002
-
(2012)
Neurobiol. Learn. Mem
, vol.97
, pp. 105-112
-
-
Jobim, P.F.1
Pedroso, T.R.2
Christoff, R.R.3
Werenicz, A.4
Maurmann, N.5
Reolon, G.K.6
-
46
-
-
84155173414
-
Impairment of object recognition memory by rapamycin inhibition of mTOR in the amygdala or hippocampus around the time of learning or reactivation
-
Jobim, P. F., Pedroso, T. R., Werenicz, A., Christoff, R. R., Maurmann, N., Reolon, G. K., et al. (2012b). Impairment of object recognition memory by rapamycin inhibition of mTOR in the amygdala or hippocampus around the time of learning or reactivation. Behav. Brain Res. 228, 151-158. doi: 10.1016/j.bbr.2011.12.004
-
(2012)
Behav. Brain Res
, vol.228
, pp. 151-158
-
-
Jobim, P.F.1
Pedroso, T.R.2
Werenicz, A.3
Christoff, R.R.4
Maurmann, N.5
Reolon, G.K.6
-
47
-
-
84908042198
-
MTOR regulates brain morphogenesis by mediating GSK3 signaling
-
Ka, M., Condorelli, G., Woodgett, J. R., and Kim, W. Y. (2014). mTOR regulates brain morphogenesis by mediating GSK3 signaling. Development 141, 4076-4086. doi: 10.1242/dev.108282
-
(2014)
Development
, vol.141
, pp. 4076-4086
-
-
Ka, M.1
Condorelli, G.2
Woodgett, J.R.3
Kim, W.Y.4
-
48
-
-
27744511769
-
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
-
Kaeberlein, M., Powers, R. W. III, Steffen, K. K., Westman, E. A., Hu, D., Dang, N. et al. (2005). Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science 310, 1193-1196. doi: 10.1126/science.1115535
-
(2005)
Science
, vol.310
, pp. 1193-1196
-
-
Kaeberlein, M.1
Powers, R.2
Steffen, K.K.3
Westman, E.A.4
Hu, D.5
Dang, N.6
-
49
-
-
0035798238
-
The molecular biology of memory storage: A dialogue between genes and synapses
-
Kandel, E. R. (2001). The molecular biology of memory storage: a dialogue between genes and synapses. Science 294, 1030-1038. doi: 10.1126/science.1067020
-
(2001)
Science
, vol.294
, pp. 1030-1038
-
-
Kandel, E.R.1
-
50
-
-
84893460020
-
BMAL1-dependent regulation of the mTOR signaling pathway delays aging
-
Khapre, R. V., Kondratova, A. A., Patel, S., Dubrovsky, Y., Wrobel, M., Antoch, M. P., et al. (2014). BMAL1-dependent regulation of the mTOR signaling pathway delays aging. Aging (Albany NY) 6, 48-57. doi: 10.18632/aging.100633
-
(2014)
Aging (Albany NY)
, vol.6
, pp. 48-57
-
-
Khapre, R.V.1
Kondratova, A.A.2
Patel, S.3
Dubrovsky, Y.4
Wrobel, M.5
Antoch, M.P.6
-
51
-
-
79959409830
-
Amino acid signaling in TOR activation
-
Kim, J., and Guan, K. L. (2011). Amino acid signaling in TOR activation. Annu. Rev. Biochem. 80, 1001-1032. doi: 10.1146/annurev-biochem-062209-094414
-
(2011)
Annu. Rev. Biochem
, vol.80
, pp. 1001-1032
-
-
Kim, J.1
Guan, K.L.2
-
52
-
-
70349130726
-
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212
-
Kim, J. Y., Duan, X., Liu, C. Y., Jang, M. H., Guo, J. U., Pow-anpongkul, N., et al. (2009). DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212. Neuron 63, 761-773. doi: 10.1016/j.neuron.2009.08.008
-
(2009)
Neuron
, vol.63
, pp. 761-773
-
-
Kim, J.Y.1
Duan, X.2
Liu, C.Y.3
Jang, M.H.4
Guo, J.U.5
Pow-Anpongkul, N.6
-
53
-
-
0036469897
-
Neurogenesis in embryos and in adult neural stem cells
-
Kintner, C. (2002). Neurogenesis in embryos and in adult neural stem cells. J. Neurosci. 22, 639-643.
-
(2002)
J. Neurosci
, vol.22
, pp. 639-643
-
-
Kintner, C.1
-
54
-
-
9944229967
-
Biochemical mechanisms for translational regulation in synaptic plasticity
-
Klann, E., and Dever, T. E. (2004). Biochemical mechanisms for translational regulation in synaptic plasticity. Nat. Rev. Neurosci. 5, 931-942. doi: 10.1038/nrn1557
-
(2004)
Nat. Rev. Neurosci
, vol.5
, pp. 931-942
-
-
Klann, E.1
Dever, T.E.2
-
55
-
-
79960016949
-
Insulin promotes dendritic spine and synapse formation by the PI3K/Akt/mTOR and Rac1 signaling pathways
-
Lee, C. C., Huang, C. C., and Hsu, K. S. (2011). Insulin promotes dendritic spine and synapse formation by the PI3K/Akt/mTOR and Rac1 signaling pathways. Neuropharmacology 61, 867-879. doi: 10.1016/j.neuropharm.2011.06.003
-
(2011)
Neuropharmacology
, vol.61
, pp. 867-879
-
-
Lee, C.C.1
Huang, C.C.2
Hsu, K.S.3
-
56
-
-
85011045053
-
Roles of mTOR signaling in brain development
-
Lee da, Y. (2015). Roles of mTOR signaling in brain development. Exp. Neurobiol. 24, 177-185. doi: 10.5607/en.2015.24.3.177
-
(2015)
Exp. Neurobiol
, vol.24
, pp. 177-185
-
-
Lee Da, Y.1
-
57
-
-
77958537034
-
Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner
-
Lee da, Y., Yeh, T. H., Emnett, R. J., White, C. R., and Gutmann, D. H. (2010). Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner. Genes Dev. 24, 2317-2329. doi: 10.1101/gad.1957110
-
(2010)
Genes Dev
, vol.24
, pp. 2317-2329
-
-
Lee Da, Y.1
Yeh, T.H.2
Emnett, R.J.3
White, C.R.4
Gutmann, D.H.5
-
58
-
-
84937815930
-
The mitochondrial uncoupler DNP triggers brain cell mTOR signaling network reprogramming and CREB pathway up-regulation
-
Liu, D., Zhang, Y., Gharavi, R., Park, H. R., Lee, J., Siddiqui, S., et al. (2015). The mitochondrial uncoupler DNP triggers brain cell mTOR signaling network reprogramming and CREB pathway up-regulation. J. Neurochem. 134, 677-692. doi: 10.1111/jnc.13176
-
(2015)
J. Neurochem
, vol.134
, pp. 677-692
-
-
Liu, D.1
Zhang, Y.2
Gharavi, R.3
Park, H.R.4
Lee, J.5
Siddiqui, S.6
-
59
-
-
84901931997
-
Systemic inhibition of mTOR kinase via rapamycin disrupts consolidation and reconsolidation of auditory fear memory
-
Mac Callum, P. E., Hebert, M., Adamec, R. E., and Blundell, J. (2014). Systemic inhibition of mTOR kinase via rapamycin disrupts consolidation and reconsolidation of auditory fear memory. Neurobiol. Learn. Mem. 112, 176-185. doi: 10.1016/j.nlm.2013.08.014
-
(2014)
Neurobiol. Learn. Mem
, vol.112
, pp. 176-185
-
-
Mac Callum, P.E.1
Hebert, M.2
Adamec, R.E.3
Blundell, J.4
-
60
-
-
84870703044
-
Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascade
-
Maiese, K., Chong, Z. Z., Wang, S., and Shang, Y. C. (2012). Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascade. Int. J. Mol. Sci. 13, 13830-13866. doi: 10.3390/ijms131113830
-
(2012)
Int. J. Mol. Sci
, vol.13
, pp. 13830-13866
-
-
Maiese, K.1
Chong, Z.Z.2
Wang, S.3
Shang, Y.C.4
-
61
-
-
27644485874
-
Oxidative stress in brain aging, neurodegenerative and vascular diseases: An overview
-
Mariani, E., Polidori, M. C., Cherubini, A., and Mecocci, P. (2005). Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 827, 65-75. doi: 10.1016/j.jchromb.2005.04.023
-
(2005)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci
, vol.827
, pp. 65-75
-
-
Mariani, E.1
Polidori, M.C.2
Cherubini, A.3
Mecocci, P.4
-
62
-
-
84946210175
-
MTORC2 and metabolic reprogramming in GBM: At the interface of genetics and environment
-
Masui, K., Cavenee, W. K., and Mischel, P. S. (2015). mTORC2 and metabolic reprogramming in GBM: at the interface of genetics and environment. Brain Pathol. 25, 755-759. doi: 10.1111/bpa.12307
-
(2015)
Brain Pathol
, vol.25
, pp. 755-759
-
-
Masui, K.1
Cavenee, W.K.2
Mischel, P.S.3
-
63
-
-
84908349843
-
Synaptic plasticity under learning challenge
-
Middei, S., Ammassari-Teule, M., and Marie, H. (2014). Synaptic plasticity under learning challenge. Neurobiol. Learn. Mem. 115, 108-115. doi: 10.1016/j.nlm.2014.08.001
-
(2014)
Neurobiol. Learn. Mem
, vol.115
, pp. 108-115
-
-
Middei, S.1
Ammassari-Teule, M.2
Marie, H.3
-
64
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima, N., Levine, B., Cuervo, A. M., and Klionsky, D. J. (2008). Autophagy fights disease through cellular self-digestion. Nature 451, 1069-1075. doi: 10.1038/nature06639
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
65
-
-
84930869090
-
Astrocyte development: A Guide for the Perplexed
-
Molofsky, A.V., and Deneen, B. (2015). Astrocyte development: a Guide for the Perplexed. Glia 63, 1320-1329. doi: 10.1002/glia.22836
-
(2015)
Glia
, vol.63
, pp. 1320-1329
-
-
Molofsky, A.V.1
Deneen, B.2
-
66
-
-
79955629005
-
Akt/mammalian target of rapamycin signaling pathway regulates neurite outgrowth in cerebellar granule neurons stimulated by methylcobalamin
-
Okada, K., Tanaka, H., Temporin, K., Okamoto, M., Kuroda, Y., Moritomo, H., et al. (2011). Akt/mammalian target of rapamycin signaling pathway regulates neurite outgrowth in cerebellar granule neurons stimulated by methylcobalamin. Neurosci. Lett. 495, 201-204. doi: 10.1016/j.neulet.2011.03.065
-
(2011)
Neurosci. Lett
, vol.495
, pp. 201-204
-
-
Okada, K.1
Tanaka, H.2
Temporin, K.3
Okamoto, M.4
Kuroda, Y.5
Moritomo, H.6
-
67
-
-
84859100570
-
The progesterone-induced enhancement of object recognition memory consolidation involves activation of the extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin (mTOR) pathways in the dorsal hippocampus
-
Orr, P. T., Rubin, A. J., Fan, L., Kent, B. A., and Frick, K. M. (2012). The progesterone-induced enhancement of object recognition memory consolidation involves activation of the extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin (mTOR) pathways in the dorsal hippocampus. Horm. Behav. 61, 487-495. doi: 10.1016/j.yhbeh.2012.01.004
-
(2012)
Horm. Behav
, vol.61
, pp. 487-495
-
-
Orr, P.T.1
Rubin, A.J.2
Fan, L.3
Kent, B.A.4
Frick, K.M.5
-
68
-
-
84867753129
-
Mammalian target of rapamycin signaling is a key regulator of the transit-amplifying progenitor pool in the adult and aging forebrain
-
Paliouras, G. N., Hamilton, L. K., Aumont, A., Joppe, S. E., Barnabe-Heider, F., and Fernandes, K. J. (2012). Mammalian target of rapamycin signaling is a key regulator of the transit-amplifying progenitor pool in the adult and aging forebrain. J. Neurosci. 32, 15012-15026. doi: 10.1523/JNEUROSCI.2248-12.2012
-
(2012)
J. Neurosci
, vol.32
, pp. 15012-15026
-
-
Paliouras, G.N.1
Hamilton, L.K.2
Aumont, A.3
Joppe, S.E.4
Barnabe-Heider, F.5
Fernandes, K.J.6
-
69
-
-
84887247782
-
Inhibition of protein synthesis or mTOR in the basolateral amygdala blocks retrieval-induced memory strengthening
-
Pedroso, T. R., Jobim, P. F., Carvalho, L. M., Christoff, R. R., Maurmann, N., Reolon, G. K., et al. (2013). Inhibition of protein synthesis or mTOR in the basolateral amygdala blocks retrieval-induced memory strengthening. J. Neural. Transm. 120, 1525-1531. doi: 10.1007/s00702-013-1032-y
-
(2013)
J. Neural. Transm
, vol.120
, pp. 1525-1531
-
-
Pedroso, T.R.1
Jobim, P.F.2
Carvalho, L.M.3
Christoff, R.R.4
Maurmann, N.5
Reolon, G.K.6
-
70
-
-
84925436842
-
MTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy
-
Perluigi, M., Di Domenico, F., and Butterfield, D. A. (2015). mTOR signaling in aging and neurodegeneration: at the crossroad between metabolism dysfunction and impairment of autophagy. Neurobiol. Dis. 84, 39-49. doi: 10.1016/j.nbd.2015.03.014
-
(2015)
Neurobiol. Dis
, vol.84
, pp. 39-49
-
-
Perluigi, M.1
Di Domenico, F.2
Butterfield, D.A.3
-
71
-
-
69449095814
-
Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling
-
Puighermanal, E., Marsicano, G., Busquets-Garcia, A., Lutz, B., Maldonado, R., and Ozaita, A. (2009). Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling. Nat. Neurosci. 12, 1152-1158. doi: 10.1038/nn.2369
-
(2009)
Nat. Neurosci
, vol.12
, pp. 1152-1158
-
-
Puighermanal, E.1
Marsicano, G.2
Busquets-Garcia, A.3
Lutz, B.4
Maldonado, R.5
Ozaita, A.6
-
72
-
-
0003631524
-
-
Sunderland, MA: Sinauer Associates
-
Purves, D. (2012). Neuroscience. Sunderland, MA: Sinauer Associates.
-
(2012)
Neuroscience
-
-
Purves, D.1
-
73
-
-
77956275001
-
Activation of mammalian target of rapamycin signaling in spatial learning
-
Qi, S., Mizuno, M., Yonezawa, K., Nawa, H., and Takei, N. (2010). Activation of mammalian target of rapamycin signaling in spatial learning. Neurosci. Res. 68, 88-93. doi: 10.1016/j.neures.2010.06.008
-
(2010)
Neurosci. Res
, vol.68
, pp. 88-93
-
-
Qi, S.1
Mizuno, M.2
Yonezawa, K.3
Nawa, H.4
Takei, N.5
-
74
-
-
0038457891
-
BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells
-
Rajan, P., Panchision, D. M., Newell, L. F., and McKay, R. D. (2003). BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells. J. Cell Biol. 161, 911-921. doi: 10.1083/jcb.200211021
-
(2003)
J. Cell Biol
, vol.161
, pp. 911-921
-
-
Rajan, P.1
Panchision, D.M.2
Newell, L.F.3
McKay, R.D.4
-
75
-
-
84876411019
-
Pharmacological inhibition of the mTOR pathway impairs hippocampal development in mice
-
Raman, L., Kong, X., and Kernie, S. G. (2013). Pharmacological inhibition of the mTOR pathway impairs hippocampal development in mice. Neurosci. Lett. 541, 9-14. doi: 10.1016/j.neulet.2013.01.045
-
(2013)
Neurosci. Lett
, vol.541
, pp. 9-14
-
-
Raman, L.1
Kong, X.2
Kernie, S.G.3
-
76
-
-
84942549317
-
FASTKD2 is associated with memory and hippocampal structure in older adults
-
Ramanan, V. K., Nho, K., Shen, L., Risacher, S. L., Kim, S., McDonald, B. C., et al. (2015). FASTKD2 is associated with memory and hippocampal structure in older adults. Mol. Psychiatry 20, 1197-1204. doi: 10.1038/mp.2014.142
-
(2015)
Mol. Psychiatry
, vol.20
, pp. 1197-1204
-
-
Ramanan, V.K.1
Nho, K.2
Shen, L.3
Risacher, S.L.4
Kim, S.5
McDonald, B.C.6
-
77
-
-
84926367856
-
Differential effects of dopamine signalling on longterm memory formation and consolidation in rodent brain
-
Reichenbach, N., Herrmann, U., Kahne, T., Schicknick, H., Pielot, R., Naumann, M., et al. (2015). Differential effects of dopamine signalling on longterm memory formation and consolidation in rodent brain. Proteome Sci. 13:13. doi: 10.1186/s12953-015-0069-2
-
(2015)
Proteome Sci
, vol.13
, pp. 13
-
-
Reichenbach, N.1
Herrmann, U.2
Kahne, T.3
Schicknick, H.4
Pielot, R.5
Naumann, M.6
-
78
-
-
84925306388
-
The proliferation of amplifying neural progenitor cells is impaired in the aging brain and restored by the mTOR pathway activation
-
Romine, J., Gao, X., Xu, X. M., So, K. F., and Chen, J. (2015). The proliferation of amplifying neural progenitor cells is impaired in the aging brain and restored by the mTOR pathway activation. Neurobiol. Aging 36, 1716-1726. doi: 10.1016/j.neurobiolaging.2015.01.003
-
(2015)
Neurobiol. Aging
, vol.36
, pp. 1716-1726
-
-
Romine, J.1
Gao, X.2
Xu, X.M.3
So, K.F.4
Chen, J.5
-
79
-
-
84926296597
-
The roles of protein expression in synaptic plasticity and memory consolidation
-
Rosenberg, T., Gal-Ben-Ari, S., Dieterich, D. C., Kreutz, M. R., Ziv, N. E., Gundelfinger, E. D., et al. (2014). The roles of protein expression in synaptic plasticity and memory consolidation. Front. Mol. Neurosci. 7:86. doi: 10.3389/fnmol.2014.00086
-
(2014)
Front. Mol. Neurosci
, vol.7
, pp. 86
-
-
Rosenberg, T.1
Gal-Ben-Ari, S.2
Dieterich, D.C.3
Kreutz, M.R.4
Ziv, N.E.5
Gundelfinger, E.D.6
-
80
-
-
17844387589
-
Embryology of neural tube development
-
Sadler, T. W. (2005). Embryology of neural tube development. Am. J. Med. Genet. C Semin. Med. Genet. 135C, 2-8. doi: 10.1002/ajmg.c.30049
-
(2005)
Am. J. Med. Genet. C Semin. Med. Genet
, vol.135C
, pp. 2-8
-
-
Sadler, T.W.1
-
81
-
-
59749087582
-
Rag proteins regulate amino-acid-induced mTORC1 signalling
-
Sancak, Y., and Sabatini, D. M. (2009). Rag proteins regulate amino-acid-induced mTORC1 signalling. Biochem. Soc. Trans. 37, 289-290. doi: 10.1042/BST0370289
-
(2009)
Biochem. Soc. Trans
, vol.37
, pp. 289-290
-
-
Sancak, Y.1
Sabatini, D.M.2
-
82
-
-
34447119468
-
Mammalian target of rapamycin: Master regulator of cell growth in the nervous system
-
Sandsmark, D. K., Pelletier, C., Weber, J. D., and Gutmann, D. H. (2007). Mammalian target of rapamycin: master regulator of cell growth in the nervous system. Histol. Histopathol. 22, 895-903.
-
(2007)
Histol. Histopathol
, vol.22
, pp. 895-903
-
-
Sandsmark, D.K.1
Pelletier, C.2
Weber, J.D.3
Gutmann, D.H.4
-
83
-
-
84904497998
-
Phosphorylation of eukaryotic translation initiation factor 4E and eukaryotic translation initiation factor 4E-binding protein (4EBP) and their upstream signaling components undergo diurnal oscillation in the mouse hippocampus: Implications for memory persistence
-
Saraf, A., Luo, J., Morris, D. R., and Storm, D. R. (2014). Phosphorylation of eukaryotic translation initiation factor 4E and eukaryotic translation initiation factor 4E-binding protein (4EBP) and their upstream signaling components undergo diurnal oscillation in the mouse hippocampus: implications for memory persistence. J. Biol. Chem. 289, 20129-20138. doi: 10.1074/jbc.M114.552638
-
(2014)
J. Biol. Chem
, vol.289
, pp. 20129-20138
-
-
Saraf, A.1
Luo, J.2
Morris, D.R.3
Storm, D.R.4
-
84
-
-
27544500981
-
Growing roles for the mTOR pathway
-
Sarbassov, D. D., Ali, S. M., and Sabatini, D. M. (2005). Growing roles for the mTOR pathway. Curr. Opin. Cell Biol. 17, 596-603. doi: 10.1016/j.ceb.2005.09.009
-
(2005)
Curr. Opin. Cell Biol
, vol.17
, pp. 596-603
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sabatini, D.M.3
-
85
-
-
84887789491
-
Effects of melatonin on nervous system aging: Neurogenesis and neurodegeneration
-
Sarlak, G., Jenwitheesuk, A., Chetsawang, B., and Govitrapong, P. (2013). Effects of melatonin on nervous system aging: neurogenesis and neurodegeneration. J. Pharmacol. Sci. 123, 9-24. doi: 10.1254/jphs.13R01SR
-
(2013)
J. Pharmacol. Sci
, vol.123
, pp. 9-24
-
-
Sarlak, G.1
Jenwitheesuk, A.2
Chetsawang, B.3
Govitrapong, P.4
-
86
-
-
54149109584
-
Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR
-
Schicknick, H., Schott, B. H., Budinger, E., Smalla, K. H., Riedel, A., Seidenbecher, C. I., et al. (2008). Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR. Cereb. Cortex 18, 2646-2658. doi: 10.1093/cercor/bhn026
-
(2008)
Cereb. Cortex
, vol.18
, pp. 2646-2658
-
-
Schicknick, H.1
Schott, B.H.2
Budinger, E.3
Smalla, K.H.4
Riedel, A.5
Seidenbecher, C.I.6
-
87
-
-
84884205500
-
Learning to learn -intrinsic plasticity as a metaplasticity mechanism for memory formation
-
Sehgal, M., Song, C., Ehlers, V. L., and Moyer, J. R. Jr. (2013). Learning to learn -intrinsic plasticity as a metaplasticity mechanism for memory formation. Neurobiol. Learn. Mem. 105, 186-199. doi: 10.1016/j.nlm.2013.07.008
-
(2013)
Neurobiol. Learn. Mem
, vol.105
, pp. 186-199
-
-
Sehgal, M.1
Song, C.2
Ehlers, V.L.3
Moyer, J.R.4
-
88
-
-
67650289960
-
BDNF activates mTOR to regulate GluR1 expression required for memory formation
-
Slipczuk, L., Bekinschtein, P., Katche, C., Cammarota, M., Izquierdo, I., and Medina, J. H. (2009). BDNF activates mTOR to regulate GluR1 expression required for memory formation. PLoS ONE 4:e6007. doi: 10.1371/journal.pone.0006007
-
(2009)
Plos ONE
, vol.4
-
-
Slipczuk, L.1
Bekinschtein, P.2
Katche, C.3
Cammarota, M.4
Izquierdo, I.5
Medina, J.H.6
-
89
-
-
84941309097
-
Mammalian target of rapamycin (MTOR) tagging promotes dendritic branch variability through the capture of Ca2+/Calmodulin-dependent protein kinase II alpha (CaMKIIalpha) mRNAs by the RNA-binding protein HuD
-
Sosanya, N. M., Cacheaux, L. P., Workman, E. R., Niere, F., Perrone-Bizzozero, N. I., and Raab-Graham, K. F. (2015). Mammalian target of rapamycin (mTOR) tagging promotes dendritic branch variability through the capture of Ca2+/Calmodulin-dependent protein kinase II alpha (CaMKIIalpha) mRNAs by the RNA-binding protein HuD. J. Biol. Chem. 290, 16357-16371. doi: 10.1074/jbc.M114.599399
-
(2015)
J. Biol. Chem
, vol.290
, pp. 16357-16371
-
-
Sosanya, N.M.1
Cacheaux, L.P.2
Workman, E.R.3
Niere, F.4
Perrone-Bizzozero, N.I.5
Raab-Graham, K.F.6
-
90
-
-
84939514534
-
Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics
-
Speranza, L., Giuliano, T., Volpicelli, F., De Stefano, M. E., Lombardi, L., Chambery, A., et al. (2015). Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics. Front. Behav. Neurosci. 9:62. doi: 10.3389/fnbeh.2015.00062
-
(2015)
Front. Behav. Neurosci
, vol.9
, pp. 62
-
-
Speranza, L.1
Giuliano, T.2
Volpicelli, F.3
De Stefano, M.E.4
Lombardi, L.5
Chambery, A.6
-
91
-
-
84897395530
-
Dynamic learning and memory, synaptic plasticity and neurogenesis: An update
-
Stuchlik, A. (2014). Dynamic learning and memory, synaptic plasticity and neurogenesis: an update. Front. Behav. Neurosci. 8:106. doi: 10.3389/fnbeh.2014.00106
-
(2014)
Front. Behav. Neurosci
, vol.8
, pp. 106
-
-
Stuchlik, A.1
-
92
-
-
84929606536
-
Postnatal high-protein diet improves learning and memory in premature rats via activation of mTOR signaling
-
Su, Z. W., Liao, J. Y., Zhang, H., Zhang, T., Wu, F., Tian, X. H., et al. (2015). Postnatal high-protein diet improves learning and memory in premature rats via activation of mTOR signaling. Brain Res. 1611, 1-7. doi: 10.1016/j.brainres.2015.01.052
-
(2015)
Brain Res
, vol.1611
, pp. 1-7
-
-
Su, Z.W.1
Liao, J.Y.2
Zhang, H.3
Zhang, T.4
Wu, F.5
Tian, X.H.6
-
93
-
-
53549099115
-
Role of the phosphoinositide 3-kinase-Akt-mammalian target of the rapamycin signaling pathway in long-term potentiation and trace fear conditioning memory in rat medial prefrontal cortex
-
Sui, L., Wang, J., and Li, B. M. (2008). Role of the phosphoinositide 3-kinase-Akt-mammalian target of the rapamycin signaling pathway in long-term potentiation and trace fear conditioning memory in rat medial prefrontal cortex. Learn. Mem. 15, 762-776. doi: 10.1101/lm.1067808
-
(2008)
Learn. Mem
, vol.15
, pp. 762-776
-
-
Sui, L.1
Wang, J.2
Li, B.M.3
-
94
-
-
38149062059
-
Role of mTOR in physiology and pathology of the nervous system
-
Swiech, L., Perycz, M., Malik, A., and Jaworski, J. (2008). Role of mTOR in physiology and pathology of the nervous system. Biochim. Biophys. Acta 1784, 116-132. doi: 10.1016/j.bbapap.2007.08.015
-
(2008)
Biochim. Biophys. Acta
, vol.1784
, pp. 116-132
-
-
Swiech, L.1
Perycz, M.2
Malik, A.3
Jaworski, J.4
-
95
-
-
84884141166
-
The role of eEF2 pathway in learning and synaptic plasticity
-
Taha, E., Gildish, I., Gal-Ben-Ari, S., and Rosenblum, K. (2013). The role of eEF2 pathway in learning and synaptic plasticity. Neurobiol. Learn. Mem. 105, 100-106. doi: 10.1016/j.nlm.2013.04.015
-
(2013)
Neurobiol. Learn. Mem
, vol.105
, pp. 100-106
-
-
Taha, E.1
Gildish, I.2
Gal-Ben-Ari, S.3
Rosenblum, K.4
-
96
-
-
84961209822
-
The role of mTOR signalling in neurogenesis, insights from tuberous sclerosis complex
-
Tee, A. R., Sampson, J. R., Pal, D. K., and Bateman, J. M. (2016). The role of mTOR signalling in neurogenesis, insights from tuberous sclerosis complex. Semin. Cell Dev. Biol. 52, 12-20. doi: 10.1016/j.semcdb.2016.01.040
-
(2016)
Semin. Cell Dev. Biol
, vol.52
, pp. 12-20
-
-
Tee, A.R.1
Sampson, J.R.2
Pal, D.K.3
Bateman, J.M.4
-
97
-
-
33745287476
-
Normal brain ageing: Models and mechanisms
-
Toescu, E. C. (2005). Normal brain ageing: models and mechanisms. Philos. Trans. R. Soc. Lond. B Biol. Sci. 360, 2347-2354. doi: 10.1098/rstb.2005.1771
-
(2005)
Philos. Trans. R. Soc. Lond. B Biol. Sci
, vol.360
, pp. 2347-2354
-
-
Toescu, E.C.1
-
98
-
-
84939431103
-
Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity
-
Triplett, J. C., Tramutola, A., Swomley, A., Kirk, J., Grimes, K., Lewis, K., et al. (2015). Age-related changes in the proteostasis network in the brain of the naked mole-rat: implications promoting healthy longevity. Biochim. Biophys. Acta 1852, 2213-2224. doi: 10.1016/j.bbadis.2015.08.002
-
(2015)
Biochim. Biophys. Acta
, vol.1852
, pp. 2213-2224
-
-
Triplett, J.C.1
Tramutola, A.2
Swomley, A.3
Kirk, J.4
Grimes, K.5
Lewis, K.6
-
99
-
-
33846569938
-
Targeting mammalian target of rapamycin (MTOR) for health and diseases
-
Tsang, C. K., Qi, H., Liu, L. F., and Zheng, X. F. (2007). Targeting mammalian target of rapamycin (mTOR) for health and diseases. Drug Discov. Today 12, 112-124. doi: 10.1016/j.drudis.2006.12.008
-
(2007)
Drug Discov. Today
, vol.12
, pp. 112-124
-
-
Tsang, C.K.1
Qi, H.2
Liu, L.F.3
Zheng, X.F.4
-
100
-
-
84912527821
-
Neurogenesis in the embryonic and adult brain: Same regulators, different roles
-
Urban, N., and Guillemot, F. (2014). Neurogenesis in the embryonic and adult brain: same regulators, different roles. Front. Cell. Neurosci. 8:396. doi: 10.3389/fncel.2014.00396
-
(2014)
Front. Cell. Neurosci
, vol.8
, pp. 396
-
-
Urban, N.1
Guillemot, F.2
-
101
-
-
84865761062
-
Mammalian target of rapamycin complex 1 (MTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neurons
-
Urbanska, M., Gozdz, A., Swiech, L. J., and Jaworski, J. (2012). Mammalian target of rapamycin complex 1 (mTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neurons. J. Biol. Chem. 287, 30240-30256. doi: 10.1074/jbc.M112.374405
-
(2012)
J. Biol. Chem
, vol.287
, pp. 30240-30256
-
-
Urbanska, M.1
Gozdz, A.2
Swiech, L.J.3
Jaworski, J.4
-
102
-
-
0642367846
-
Genetics: Influence of TOR Kinase on lifespan in C. Elegans
-
Vellai, T., Takacs-Vellai, K., Zhang, Y., Kovacs, A. L., Orosz, L., and Muller, F. (2003). Genetics: influence of TOR kinase on lifespan in C. elegans. Nature 426:620. doi: 10.1038/426620a
-
(2003)
Nature
, vol.426
, pp. 620
-
-
Vellai, T.1
Takacs-Vellai, K.2
Zhang, Y.3
Kovacs, A.L.4
Orosz, L.5
Muller, F.6
-
103
-
-
84903985731
-
PI3K-p110-alpha-subtype signalling mediates survival, proliferation and neurogenesis of cortical progenitor cells via activation of mTORC2
-
Wahane, S. D., Hellbach, N., Prentzell, M. T., Weise, S. C., Vezzali, R., Kreutz, C., et al. (2014). PI3K-p110-alpha-subtype signalling mediates survival, proliferation and neurogenesis of cortical progenitor cells via activation of mTORC2. J. Neurochem. 130, 255-267. doi: 10.1111/jnc.12718
-
(2014)
J. Neurochem
, vol.130
, pp. 255-267
-
-
Wahane, S.D.1
Hellbach, N.2
Prentzell, M.T.3
Weise, S.C.4
Vezzali, R.5
Kreutz, C.6
-
104
-
-
46649087778
-
Nogo-66 promotes the differentiation of neural progenitors into astroglial lineage cells through mTOR-STAT3 pathway
-
Wang, B., Xiao, Z., Chen, B., Han, J., Gao, Y., Zhang, J., et al. (2008). Nogo-66 promotes the differentiation of neural progenitors into astroglial lineage cells through mTOR-STAT3 pathway. PLoS ONE 3:e1856. doi: 10.1371/journal.pone.0001856
-
(2008)
Plos ONE
, vol.3
-
-
Wang, B.1
Xiao, Z.2
Chen, B.3
Han, J.4
Gao, Y.5
Zhang, J.6
-
105
-
-
0035881470
-
Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase
-
Wang, X., Li, W., Williams, M., Terada, N., Alessi, D. R., and Proud, C. G. (2001). Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase. EMBO J. 20, 4370-4379. doi: 10.1093/emboj/20.16.4370.
-
(2001)
EMBO J
, vol.20
, pp. 4370-4379
-
-
Wang, X.1
Li, W.2
Williams, M.3
Terada, N.4
Alessi, D.R.5
Proud, C.G.6
-
106
-
-
84856078168
-
Deconvoluting mTOR biology
-
Weber, J. D., and Gutmann, D. H. (2012). Deconvoluting mTOR biology. Cell Cycle 11, 236-248. doi: 10.4161/cc.11.2.19022
-
(2012)
Cell Cycle
, vol.11
, pp. 236-248
-
-
Weber, J.D.1
Gutmann, D.H.2
-
107
-
-
84880302658
-
Thyroid hormone-dependent development of early cortical networks: Temporal specificity and the contribution of trkB and mTOR pathways
-
Westerholz, S., de Lima, A. D., and Voigt, T. (2013). Thyroid hormone-dependent development of early cortical networks: temporal specificity and the contribution of trkB and mTOR pathways. Front. Cell. Neurosci. 7:121. doi: 10.3389/fncel.2013.00121
-
(2013)
Front. Cell. Neurosci
, vol.7
, pp. 121
-
-
Westerholz, S.1
De Lima, A.D.2
Voigt, T.3
-
108
-
-
84876783653
-
MTOR: A link from the extracellular milieu to transcriptional regulation of oligodendrocyte development
-
Wood, T. L., Bercury, K. K., Cifelli, S. E., Mursch, L. E., Min, J., Dai, J., et al. (2013). mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development. ASN Neuro 5:e00108. doi: 10.1042/AN20120092
-
(2013)
ASN Neuro
, vol.5
-
-
Wood, T.L.1
Bercury, K.K.2
Cifelli, S.E.3
Mursch, L.E.4
Min, J.5
Dai, J.6
-
109
-
-
84896722838
-
Niu, Y., et al. (2014). mTOR and autophagy in normal brain aging and caloric restriction ameliorating age-related cognition deficits
-
Yang, F., Chu, X., Yin, M., Liu, X., Yuan, H., Niu, Y., et al. (2014). mTOR and autophagy in normal brain aging and caloric restriction ameliorating age-related cognition deficits. Behav. Brain Res. 264, 82-90. doi: 10.1016/j.bbr.2014.02.005
-
Behav. Brain Res
, vol.264
, pp. 82-90
-
-
Yang, F.1
Chu, X.2
Yin, M.3
Liu, X.4
Yuan, H.5
-
110
-
-
84939781204
-
Subcellular distribution and activity of mechanistic target of rapamycin in aged retinal pigment epithelium
-
Yu, B., Xu, P., Zhao, Z., Cai, J., Sternberg, P., and Chen, Y. (2014). Subcellular distribution and activity of mechanistic target of rapamycin in aged retinal pigment epithelium. Invest. Ophthalmol. Vis. Sci. 55, 8638-8650. doi: 10.1167/iovs.14-14758
-
(2014)
Invest. Ophthalmol. Vis. Sci
, vol.55
, pp. 8638-8650
-
-
Yu, B.1
Xu, P.2
Zhao, Z.3
Cai, J.4
Sternberg, P.5
Chen, Y.6
-
111
-
-
84899479091
-
Ezh2 regulates adult hippocampal neurogenesis and memory
-
Zhang, J., Ji, F., Liu, Y., Lei, X., Li, H., Ji, G., et al. (2014). Ezh2 regulates adult hippocampal neurogenesis and memory. J. Neurosci. 34, 5184-5199. doi: 10.1523/JNEUROSCI.4129-13.2014
-
(2014)
J. Neurosci
, vol.34
, pp. 5184-5199
-
-
Zhang, J.1
Ji, F.2
Liu, Y.3
Lei, X.4
Li, H.5
Ji, G.6
-
112
-
-
39149107803
-
Mechanisms and functional implications of adult neurogenesis
-
Zhao, C., Deng, W., and Gage, F. H. (2008). Mechanisms and functional implications of adult neurogenesis. Cell 132, 645-660. doi: 10.1016/j.cell.2008.01.033.
-
(2008)
Cell
, vol.132
, pp. 645-660
-
-
Zhao, C.1
Deng, W.2
Gage, F.H.3
-
113
-
-
84901571551
-
Pro-neurogenesis and anti-dementia properties of tetradecyl 2,3-dihydroxybenzoate through TrkA receptor-mediated signalling pathways
-
Zhou, L., Lu, Z., Li, L., Chen, L., Qi, J., and Chen, L. (2014). Pro-neurogenesis and anti-dementia properties of tetradecyl 2,3-dihydroxybenzoate through TrkA receptor-mediated signalling pathways. Int. J. Neuropsychopharmacol. 17, 1847-1861. doi: 10.1017/S1461145714000558
-
(2014)
Int. J. Neuropsychopharmacol
, vol.17
, pp. 1847-1861
-
-
Zhou, L.1
Lu, Z.2
Li, L.3
Chen, L.4
Qi, J.5
Chen, L.6
-
114
-
-
84874284862
-
MTOR Inhibition ameliorates cognitive and affective deficits caused by Disc1 knockdown in adult-born dentate granule neurons
-
Zhou, M., Li, W., Huang, S., Song, J., Kim, J. Y., Tian, X., et al. (2013). mTOR Inhibition ameliorates cognitive and affective deficits caused by Disc1 knockdown in adult-born dentate granule neurons. Neuron 77, 647-654. doi: 10.1016/j.neuron.2012.12.033
-
(2013)
Neuron
, vol.77
, pp. 647-654
-
-
Zhou, M.1
Li, W.2
Huang, S.3
Song, J.4
Kim, J.Y.5
Tian, X.6
-
115
-
-
78650510609
-
MTOR: From growth signal integration to cancer, diabetes and ageing
-
Zoncu, R., Efeyan, A., and Sabatini, D. M. (2011). mTOR: from growth signal integration to cancer, diabetes and ageing. Nat. Rev. Mol. Cell Biol. 12, 21-35. doi: 10.1038/nrm3025
-
(2011)
Nat. Rev. Mol. Cell Biol
, vol.12
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.M.3
-
116
-
-
84911443008
-
Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain
-
Zou, Y., Jiang, W., Wang, J., Li, Z., Zhang, J., Bu, J., et al. (2014). Oligodendrocyte precursor cell-intrinsic effect of Rheb1 controls differentiation and mediates mTORC1-dependent myelination in brain. J. Neurosci. 34, 15764-15778. doi: 10.1523/JNEUROSCI.2267-14.2014
-
(2014)
J. Neurosci
, vol.34
, pp. 15764-15778
-
-
Zou, Y.1
Jiang, W.2
Wang, J.3
Li, Z.4
Zhang, J.5
Bu, J.6
-
117
-
-
84887402039
-
Intrinsic and extrinsic control of oligodendrocyte development
-
Zuchero, J. B., and Barres, B. A. (2013). Intrinsic and extrinsic control of oligodendrocyte development. Curr. Opin. Neurobiol. 23, 914-920. doi: 10.1016/j.conb.2013.06.005
-
(2013)
Curr. Opin. Neurobiol
, vol.23
, pp. 914-920
-
-
Zuchero, J.B.1
Barres, B.A.2
|