Neurofibromatosis-1 regulates neuroglial progenitor proliferation and glial differentiation in a brain region-specific manner

Genes and Development

Volumn 24, Issue 20, 2010, Pages 2317-2329

  Lee, Da Yong ^a   Yeh, Tu Hsueh ^a,b   Emnett, Ryan J ^a   White, Crystal R ^a   Gutmann, David H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Akt; Gliogenesis; mTOR; Neural stem cell; Neurofibromin; Regional heterogeneity

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; NEUROFIBROMIN; PROTEIN KINASE B; PROTEIN P27;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN REGION; CELL CULTURE; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CELL RENEWAL; CELL SPECIFICITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; FEMALE; GENE INACTIVATION; GLIA CELL; GLIOGENESIS; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MOUSE; NEOCORTEX; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; STEM CELL; TRANSGENIC ORGANISM;

ANIMALS; BLOTTING, WESTERN; BRAIN; BRAIN STEM; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CEREBRAL CORTEX; FEMALE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUROFIBROMIN 1; NEUROGENESIS; NEUROGLIA; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; STEM CELLS;

MAMMALIA; MUS;

EID: 77958537034     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1957110     Document Type: Article

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