Autophagy involving age-related cognitive behavior and hippocampus injury is modulated by different caloric intake in mice

International Journal of Clinical and Experimental Medicine

Volumn 8, Issue 7, 2015, Pages 11843-11853

  Dong, Wen ^a   Wang, Rong ^a   Ma, Li Na ^a   Xu, Bao Lei ^b   Zhang, Jing Shuang ^a   Zhao, Zhi Wei ^a   Wang, Yu Lan ^a   Zhang, Xu ^a  

^a BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Autophagy; Caloric restriction; Cognitive behavior; High caloric intake; Obesity

Indexed keywords

BECLIN 1; CATHEPSIN B; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN P62;

ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CALORIC INTAKE; CELL DENSITY; CONTROLLED STUDY; HIPPOCAMPUS; IMMUNOFLUORESCENCE; LEARNING; MALE; MEMORY; MORRIS WATER MAZE TEST; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RISK FACTOR; WESTERN BLOTTING;

EID: 84940703527     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Van den Berg E, Kloppenborg RP, Kessels RP, Kappelle LJ, Biessels GJ. Type 2 diabetes mellitus, hypertension, dyslipidemia and obesity: A systematic comparison of their impact on cognition. Biochim Biophys Acta 2009; 1792: 470-81.
2. Arnoldussen IA, Kiliaan AJ, Gustafson DR. Obesity and dementia: adipokines interact with the brain. Eur Neuropsychopharmacol 2014; 24: 1982-99.
3. Businaro R, Ippoliti F, Ricci S, Canitano N, Fuso A. Alzheimer's disease promotion by obesity: induced mechanisms-molecular links and perspectives. Curr Gerontol Geriatr Res 2012; 2012: 986823.
4. Gustafson D. A life course of adiposity and dementia. Eur J Pharmacol 2008; 585: 163-75.
5. Schroeder JE, Richardson JC, Virley DJ. Dietary manipulation and caloric restriction in the development of mouse models relevant to neurological diseases. Biochim Biophys Acta 2010; 1802: 840-6.
6. Koyama A, Houston DK, Simonsick EM, Lee JS, Ayonayon HN, Shahar DR, Rosano C, Satterfield S, Yaffe K. Association Between the Mediterranean Diet and Cognitive Decline in a Biracial Population. J Gerontol A Biol Sci Med Sci 2014.
7. Profenno LA, Porsteinsson AP, Faraone SV. Meta-analysis of Alzheimer's disease risk with obesity, diabetes, and related disorders. Biol Psychiatry 2010; 67: 505-12.
8. Herculano B, Tamura M, Ohba A, Shimatani M, Kutsuna N, Hisatsune T. beta-alanyl-L-histidine rescues cognitive deficits caused by feeding a high fat diet in a transgenic mouse model of Alzheimer's disease. J Alzheimers Dis 2013; 33: 983-97.
9. Cui M, Yu H, Wang J, Gao J, Li J. Chronic caloric restriction and exercise improve metabolic conditions of dietary-induced obese mice in autophagy correlated manner without involving AMPK. J Diabetes Res 2013; 2013: 852754.
10. Jiang T, Liebman SE, Lucia MS, Phillips CL, Levi M. Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease. J Am Soc Nephrol 2005; 16: 2385-94.
11. Mager DE, Wan R, Brown M, Cheng A, Wareski P, Abernethy DR, Mattson MP. Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats. FASEB J 2006; 20: 631-7.
12. Nicoletti VG, Marino VM, Cuppari C, Licciardello D, Patti D, Purrello VS, Stella AM. Effect of antioxidant diets on mitochondrial gene expression in rat brain during aging. Neurochem Res 2005; 30: 737-52.
13. Mattson MP. Energy intake, meal frequency, and health: a neurobiological perspective. Annu Rev Nutr 2005; 25: 237-60.
14. Choi AM, Ryter SW, Levine B. Autophagy in human health and disease. N Engl J Med 2013; 368: 1845-6.
15. Rubinsztein DC, Marino G, Kroemer G. Autophagy and aging. Cell 2011; 146: 682-95.
16. Tanaka Y, Kume S, Kitada M, Kanasaki K, Uzu T, Maegawa H, Koya D. Autophagy as a therapeutic target in diabetic nephropathy. Exp Diabetes Res 2012; 2012: 628978.
17. Wolfe DM, Lee JH, Kumar A, Lee S, Orenstein SJ, Nixon RA. Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification. Eur J Neurosci 2013; 37: 1949-61.
18. Nixon RA. Alzheimer neurodegeneration, autophagy, and Abeta secretion: the ins and outs (comment on DOI 10.1002/bies.201400002). Bioessays 2014; 36: 547.
19. Korolchuk VI, Rubinsztein DC. Regulation of autophagy by lysosomal positioning. Autophagy 2011; 7: 927-8.
20. Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 2009; 460: 392-5.
21. Viscomi MT, D'Amelio M, Cavallucci V, Latini L, Bisicchia E, Nazio F, Fanelli F, Maccarrone M, Moreno S, Cecconi F, Molinari M. Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage. Autophagy 2012; 8: 222-35.
22. Yang Y, Chen S, Zhang J, Li C, Sun Y, Zhang L, Zheng X. Stimulation of autophagy prevents amyloid-beta peptide-induced neuritic degeneration in PC12 cells. J Alzheimers Dis 2014; 40: 929-39.
23. Ma L, Dong W, Wang R, Li Y, Xu B, Zhang J, Zhao Z, Wang Y. Effect of caloric restriction on the SIRT1/mTOR signaling pathways in senile mice. Brain Res Bull 2015; 116: 67-72.
24. Yun HM, Kim HS, Park KR, Shin JM, Kang AR, il Lee K, Song S, Kim YB, Han SB, Chung HM, Hong JT. Placenta-derived mesenchymal stem cells improve memory dysfunction in an Abeta1-42-infused mouse model of Alzheimer's disease. Cell Death Dis 2013; 4: e958.
25. Zhou XM, Zhou ML, Zhang XS, Zhuang Z, Li T, Shi JX, Zhang X. Resveratrol prevents neuronal apoptosis in an early brain injury model. J Surg Res 2014; 189: 159-65.
26. Volpe BT, Davis HP, Towle A, Dunlap WP. Loss of hippocampal CA1 pyramidal neurons correlates with memory impairment in rats with ischemic or neurotoxin lesions. Behav Neurosci 1992; 106: 457-64.
27. Hartman RE, Lee JM, Zipfel GJ, Wozniak DF. Characterizing learning deficits and hippocampal neuron loss following transient global cerebral ischemia in rats. Brain Res 2005; 1043: 48-56.
28. Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, Tanida I, Ueno T, Koike M, Uchiyama Y, Kominami E,Tanaka K. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006; 441: 880-4.
29. Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka K. Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 2007; 131: 1149-63.
30. Ruohonen ST, Vahatalo LH, Savontaus E. Diet-induced obesity in mice overexpressing neuropeptide y in noradrenergic neurons. Int J Pept 2012; 2012: 452524.
31. Lee J, Duan W, Long JM, Ingram DK, Mattson MP. Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats. J Mol Neurosci 2000; 15: 99-108.
32. Lee J, Seroogy KB, Mattson MP. Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice. J Neurochem 2002; 80: 539-47.
33. Yamamoto A, Yue Z. Autophagy and its normal and pathogenic states in the brain. Annu Rev Neurosci 2014; 37: 55-78.
34. Caballero B, Coto-Montes A. An insight into the role of autophagy in cell responses in the aging and neurodegenerative brain. Histol Histopathol 2012; 27: 263-75.
35. Ma L, Zhao Z, Wang R, Zhang X, Zhang J, Dong W, Xu B, Zhang J. Caloric restriction can improve learning ability in C57/BL mice via regulation of the insulin-PI3K/Akt signaling pathway. Neurol Sci 2014.
36. Dal-Pan A, Pifferi F, Marchal J, Picq JL, Aujard F, Consortium R. Cognitive performances are selectively enhanced during chronic caloric restriction or resveratrol supplementation in a primate. PLoS One 2011; 6: e16581.
37. Gottlieb RA, Carreira RS. Autophagy in health and disease. 5. Mitophagy as a way of life. Am J Physiol Cell Physiol 2010; 299: C203-10.
38. Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell 2012; 149: 274-93.
39. Yang F, Chu X, Yin M, Liu X, Yuan H, Niu Y, Fu L. mTOR and autophagy in normal brain aging and caloric restriction ameliorating age-related cognition deficits. Behav Brain Res 2014; 264: 82-90.
40. Blagosklonny MV. Calorie restriction: decelerating mTOR-driven aging from cells to organisms (including humans). Cell Cycle 2010; 9: 683-8.
41. Tzatsos A, Kandror KV. Nutrients suppress phosphatidylinositol 3-kinase/Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation. Mol Cell Biol 2006; 26: 63-76.
42. Ning YC, Cai GY, Zhuo L, Gao JJ, Dong D, Cui S, Feng Z, Shi SZ, Bai XY, Sun XF, Chen XM. Short-term calorie restriction protects against renal senescence of aged rats by increasing autophagic activity and reducing oxidative damage. Mech Ageing Dev 2013; 134: 570-9.