Systemic inhibition of mTOR kinase via rapamycin disrupts consolidation and reconsolidation of auditory fear memory

Neurobiology of Learning and Memory

Volumn 112, Issue , 2014, Pages 176-185

  Mac Callum, Phillip E ^a   Hebert, Mark ^a   Adamec, Robert E ^a   Blundell, Jacqueline ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

Auditory fear memory; Consolidation; MTOR; Posttraumatic stress disorder; Rapamycin; Reconsolidation

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; TARGET OF RAPAMYCIN KINASE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY FEAR MEMORY; AUDITORY MEMORY; CONTROLLED STUDY; DRUG MECHANISM; EMOTIONALITY; ENZYME INHIBITION; FEAR; LONG TERM MEMORY; MALE; MEMORY CONSOLIDATION; MOUSE; NONHUMAN; REGULATORY MECHANISM; SHORT TERM MEMORY; TASK PERFORMANCE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CONDITIONED REFLEX; DRUG EFFECTS; HEARING; PHYSIOLOGY; SIGNAL TRANSDUCTION; TIME;

ANIMALS; AUDITORY PERCEPTION; CONDITIONING, CLASSICAL; FEAR; MALE; MEMORY, LONG-TERM; MICE, INBRED C57BL; SIGNAL TRANSDUCTION; SIROLIMUS; TIME FACTORS; TOR SERINE-THREONINE KINASES;

EID: 84901931997     PISSN: 10747427     EISSN: 10959564     Source Type: Journal    
DOI: 10.1016/j.nlm.2013.08.014     Document Type: Article

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