MTORC1 Targets the Translational Repressor 4E-BP2, but Not S6 Kinase 1/2, to Regulate Neural Stem Cell Self-Renewal InVivo

Cell Reports

Volumn 5, Issue 2, 2013, Pages 433-444

  Hartman, Nathaniel W ^a   Lin, Tiffany V ^a   Zhang, Longbo ^a   Paquelet, Grace E ^a   Feliciano, David M ^a   Bordey, Angélique ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4E BP2 PROTEIN; INITIATION FACTOR 4E BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; S6 KINASE; UNCLASSIFIED DRUG; CARRIER PROTEIN; EIF4EBP1 PROTEIN, MOUSE; EIF4EBP2 PROTEIN, MOUSE; INITIATION FACTOR; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MULTIPROTEIN COMPLEX; NEUROPEPTIDE; PHOSPHOPROTEIN; RAPAMYCIN; RHEB PROTEIN, MOUSE; RIBOSOMAL PROTEIN S6 KINASE, 90KDA, POLYPEPTIDE 3; RPS6KA1 PROTEIN, MOUSE; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ARTICLE; CELL LINEAGE; CELL RENEWAL; CONTROLLED STUDY; GENE ACTIVITY; GENE INDUCTION; GENE TARGETING; IN VIVO STUDY; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEWBORN; NONHUMAN; PERINATAL DEVELOPMENT; PRIORITY JOURNAL; STEM CELL EXPANSION; TRANSLATION REGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; PHOSPHORYLATION; RNA INTERFERENCE;

MAMMALIA;

ANIMALS; CARRIER PROTEINS; CELL DIFFERENTIATION; CELLS, CULTURED; EUKARYOTIC INITIATION FACTORS; MICE; MONOMERIC GTP-BINDING PROTEINS; MULTIPROTEIN COMPLEXES; NEURAL STEM CELLS; NEUROPEPTIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84887017909     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2013.09.017     Document Type: Article

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