Inhibition of mTOR by rapamycin in the amygdala or hippocampus impairs formation and reconsolidation of inhibitory avoidance memory

Neurobiology of Learning and Memory

Volumn 97, Issue 1, 2012, Pages 105-112

  Jobim, Paulo F C ^a,b   Pedroso, Thiago R ^a,b   Christoff, Raissa R ^a   Werenicz, Aline ^a   Maurmann, Natasha ^a,b   Reolon, Gustavo K ^a,b   Roesler, Rafael ^a,b,c  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b National Institute for Translational Medicine INCT TM   (Brazil)

^c HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Consolidation; Inhibitory avoidance; MTOR; Protein synthesis; Rapamycin; Reconsolidation

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVOIDANCE BEHAVIOR; BASOLATERAL AMYGDALA; BRAIN REGION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LOCALIZATION; HIPPOCAMPUS; INHIBITORY AVOIDANCE; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; NEUROTOXICITY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT;

AMYGDALA; ANIMALS; AVOIDANCE LEARNING; ELECTROSHOCK; HIPPOCAMPUS; MALE; MEMORY; NEURONS; RATS; RATS, WISTAR; RETENTION (PSYCHOLOGY); SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84155186458     PISSN: 10747427     EISSN: 10959564     Source Type: Journal    
DOI: 10.1016/j.nlm.2011.10.002     Document Type: Article

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