메뉴 건너뛰기




Volumn 60, Issue , 2015, Pages 60-65

NMDA receptor activation regulates sociability by its effect on mTOR signaling activity

Author keywords

D Cycloserine; mTOR; NMDA receptor; Sociability; Tuberous sclerosis

Indexed keywords

ARGININE; CYCLOSERINE; GLUTAMIC ACID; GLYCINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE; RAPAMYCIN; STRIATAL ENRICHED PROTEIN TYROSINE PHOSPHATASE; TUBERIN; UNCLASSIFIED DRUG; TARGET OF RAPAMYCIN KINASE;

EID: 84923369865     PISSN: 02785846     EISSN: 18784216     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2015.02.009     Document Type: Review
Times cited : (49)

References (58)
  • 1
    • 84887176861 scopus 로고    scopus 로고
    • Balb/c mice treated with D-cycloserine arouse increased social interest in conspecifics
    • [Oct]
    • Benson A.D., Burket J.A., Deutsch S.I. Balb/c mice treated with D-cycloserine arouse increased social interest in conspecifics. Brain Res Bull 2013, 99:95-99. [Oct].
    • (2013) Brain Res Bull , vol.99 , pp. 95-99
    • Benson, A.D.1    Burket, J.A.2    Deutsch, S.I.3
  • 3
    • 33845319742 scopus 로고    scopus 로고
    • BALB/c mice: low sociability and other phenotypes that may be relevant to autism
    • [Jan 10]
    • Brodkin E.S. BALB/c mice: low sociability and other phenotypes that may be relevant to autism. Behav Brain Res 2007, 176(1):53-65. [Jan 10].
    • (2007) Behav Brain Res , vol.176 , Issue.1 , pp. 53-65
    • Brodkin, E.S.1
  • 4
    • 43449090970 scopus 로고    scopus 로고
    • Social behavior phenotypes in fragile X syndrome, autism, and the Fmr1 knockout mouse: theoretical comment on McNaughton et al. (2008)
    • [Apr]
    • Brodkin E.S. Social behavior phenotypes in fragile X syndrome, autism, and the Fmr1 knockout mouse: theoretical comment on McNaughton et al. (2008). Behav Neurosci 2008, 122(2):483-489. [Apr].
    • (2008) Behav Neurosci , vol.122 , Issue.2 , pp. 483-489
    • Brodkin, E.S.1
  • 5
    • 78149285467 scopus 로고    scopus 로고
    • MK-801, a noncompetitive NMDA receptor antagonist, elicits circling behavior in the genetically inbred Balb/c mouse strain
    • Burket J.A., Cannon W.R., Jacome L.F., Deutsch S.I. MK-801, a noncompetitive NMDA receptor antagonist, elicits circling behavior in the genetically inbred Balb/c mouse strain. Brain Res Bull 2010 Nov 20, 83(6):337-339.
    • (2010) Brain Res Bull , vol.83 , Issue.6 , pp. 337-339
    • Burket, J.A.1    Cannon, W.R.2    Jacome, L.F.3    Deutsch, S.I.4
  • 6
    • 77957655037 scopus 로고    scopus 로고
    • Locomotor activity of the genetically inbred Balb/c mouse strain is suppressed by a socially salient stimulus
    • Burket J.A., Herndon A.L., Deutsch S.I. Locomotor activity of the genetically inbred Balb/c mouse strain is suppressed by a socially salient stimulus. Brain Res Bull 2010 Oct 30, 83(5):255-256.
    • (2010) Brain Res Bull , vol.83 , Issue.5 , pp. 255-256
    • Burket, J.A.1    Herndon, A.L.2    Deutsch, S.I.3
  • 7
    • 84878804982 scopus 로고    scopus 로고
    • D-Cycloserine improves sociability in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders with altered Ras/Raf/ERK1/2 signaling
    • [Jul]
    • Burket J.A., Benson A.D., Tang A.H., Deutsch S.I. D-Cycloserine improves sociability in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders with altered Ras/Raf/ERK1/2 signaling. Brain Res Bull 2013, 96:62-70. [Jul].
    • (2013) Brain Res Bull , vol.96 , pp. 62-70
    • Burket, J.A.1    Benson, A.D.2    Tang, A.H.3    Deutsch, S.I.4
  • 8
    • 84890811053 scopus 로고    scopus 로고
    • Rapamycin improves sociability in the BTBR T(+)Itpr3(tf)/J mouse model of autism spectrum disorders
    • [Jan]
    • Burket J.A., Benson A.D., Tang A.H., Deutsch S.I. Rapamycin improves sociability in the BTBR T(+)Itpr3(tf)/J mouse model of autism spectrum disorders. Brain Res Bull 2014, 100:70-75. [Jan].
    • (2014) Brain Res Bull , vol.100 , pp. 70-75
    • Burket, J.A.1    Benson, A.D.2    Tang, A.H.3    Deutsch, S.I.4
  • 10
    • 84873325835 scopus 로고    scopus 로고
    • Behavioural and EEG effects of chronic rapamycin treatment in a mouse model of tuberous sclerosis complex
    • [Apr]
    • Cambiaghi M., Cursi M., Magri L., Castoldi V., Comi G., Minicucci F., et al. Behavioural and EEG effects of chronic rapamycin treatment in a mouse model of tuberous sclerosis complex. Neuropharmacology 2013, 67:1-7. [Apr].
    • (2013) Neuropharmacology , vol.67 , pp. 1-7
    • Cambiaghi, M.1    Cursi, M.2    Magri, L.3    Castoldi, V.4    Comi, G.5    Minicucci, F.6
  • 11
    • 84908673831 scopus 로고    scopus 로고
    • New experimental treatments for core social domain in autism spectrum disorders
    • Canitano R. New experimental treatments for core social domain in autism spectrum disorders. Front Pediatr 2014, 2:61.
    • (2014) Front Pediatr , vol.2 , pp. 61
    • Canitano, R.1
  • 12
    • 84855958205 scopus 로고    scopus 로고
    • MTOR: a pathogenic signaling pathway in developmental brain malformations
    • [Dec]
    • Crino P.B. mTOR: a pathogenic signaling pathway in developmental brain malformations. Trends Mol Med 2011, 17(12):734-742. [Dec].
    • (2011) Trends Mol Med , vol.17 , Issue.12 , pp. 734-742
    • Crino, P.B.1
  • 13
    • 65449139457 scopus 로고    scopus 로고
    • Autism-specific copy number variants further implicate the phosphatidylinositol signaling pathway and the glutamatergic synapse in the etiology of the disorder
    • [May 15]
    • Cuscó I., Medrano A., Gener B., Vilardell M., Gallastegui F., Villa O., et al. Autism-specific copy number variants further implicate the phosphatidylinositol signaling pathway and the glutamatergic synapse in the etiology of the disorder. Hum Mol Genet 2009, 18(10):1795-1804. [May 15].
    • (2009) Hum Mol Genet , vol.18 , Issue.10 , pp. 1795-1804
    • Cuscó, I.1    Medrano, A.2    Gener, B.3    Vilardell, M.4    Gallastegui, F.5    Villa, O.6
  • 14
    • 84888434839 scopus 로고    scopus 로고
    • Prescriptive variables for d-cycloserine augmentation of exposure therapy for posttraumatic stress disorder
    • [Jan]
    • De Kleine R.A., Hendriks G.-J., Smits J.A.J., Broekman T.G., van Minnen A. Prescriptive variables for d-cycloserine augmentation of exposure therapy for posttraumatic stress disorder. J Psychiatr Res 2014, 48(1):40-46. [Jan].
    • (2014) J Psychiatr Res , vol.48 , Issue.1 , pp. 40-46
    • De Kleine, R.A.1    Hendriks, G.-J.2    Smits, J.A.J.3    Broekman, T.G.4    van Minnen, A.5
  • 15
    • 0030983012 scopus 로고    scopus 로고
    • Inbred mouse strains differ in sensitivity to "popping" behavior elicited by MK-801
    • [Jun]
    • Deutsch S.I., Rosse R.B., Paul S.M., Riggs R.L., Mastropaolo J. Inbred mouse strains differ in sensitivity to "popping" behavior elicited by MK-801. Pharmacol Biochem Behav 1997, 57(1-2):315-317. [Jun].
    • (1997) Pharmacol Biochem Behav , vol.57 , Issue.1-2 , pp. 315-317
    • Deutsch, S.I.1    Rosse, R.B.2    Paul, S.M.3    Riggs, R.L.4    Mastropaolo, J.5
  • 16
    • 0031818591 scopus 로고    scopus 로고
    • Inbred mouse strains differ in their sensitivity to an antiseizure effect of MK-801
    • [Aug]
    • Deutsch S.I., Mastropaolo J., Powell D.G., Rosse R.B., Bachus S.E. Inbred mouse strains differ in their sensitivity to an antiseizure effect of MK-801. Clin Neuropharmacol 1998, 21(4):255-257. [Aug].
    • (1998) Clin Neuropharmacol , vol.21 , Issue.4 , pp. 255-257
    • Deutsch, S.I.1    Mastropaolo, J.2    Powell, D.G.3    Rosse, R.B.4    Bachus, S.E.5
  • 17
    • 78650311460 scopus 로고    scopus 로고
    • D-Cycloserine improves the impaired sociability of the Balb/c mouse
    • [Jan 15]
    • Deutsch S.I., Burket J.A., Jacome L.F., Cannon W.R., Herndon A.L. D-Cycloserine improves the impaired sociability of the Balb/c mouse. Brain Res Bull 2011, 84(1):8-11. [Jan 15].
    • (2011) Brain Res Bull , vol.84 , Issue.1 , pp. 8-11
    • Deutsch, S.I.1    Burket, J.A.2    Jacome, L.F.3    Cannon, W.R.4    Herndon, A.L.5
  • 18
    • 84923377193 scopus 로고    scopus 로고
    • Impaired sociability of the Balb/c mouse, an animal model of autism spectrum disorders, is attenuated by NMDA receptor agonist interventions: clinical implications
    • InTech, M. Mohammad-Reza (Ed.)
    • Deutsch S.I., Burket J.A., Urbano M.R., Herndon A.L., Winebarger E.E. Impaired sociability of the Balb/c mouse, an animal model of autism spectrum disorders, is attenuated by NMDA receptor agonist interventions: clinical implications. Compr Book Autism Spectr Disord [Internet] 2011, InTech, [Available from: http://www.intechopen.com/articles/show/title/impaired-sociability-of-the-Balb-c-mouse-an-animal-model-of-autism-spectrum-disorders-is-attenuated-]. M. Mohammad-Reza (Ed.).
    • (2011) Compr Book Autism Spectr Disord [Internet]
    • Deutsch, S.I.1    Burket, J.A.2    Urbano, M.R.3    Herndon, A.L.4    Winebarger, E.E.5
  • 19
    • 84856615330 scopus 로고    scopus 로고
    • D-cycloserine improves sociability and spontaneous stereotypic behaviors in 4-week old mice
    • [Feb 23]
    • Deutsch S.I., Pepe G.J., Burket J.A., Winebarger E.E., Herndon A.L., Benson A.D. D-cycloserine improves sociability and spontaneous stereotypic behaviors in 4-week old mice. Brain Res 2012, 1439:96-107. [Feb 23].
    • (2012) Brain Res , vol.1439 , pp. 96-107
    • Deutsch, S.I.1    Pepe, G.J.2    Burket, J.A.3    Winebarger, E.E.4    Herndon, A.L.5    Benson, A.D.6
  • 20
    • 84896388390 scopus 로고    scopus 로고
    • D-cycloserine augmentation of exposure therapy for post-traumatic stress disorder: a pilot randomized clinical trial
    • [Apr]
    • Difede J., Cukor J., Wyka K., Olden M., Hoffman H., Lee F.S., et al. D-cycloserine augmentation of exposure therapy for post-traumatic stress disorder: a pilot randomized clinical trial. Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol 2014, 39(5):1052-1058. [Apr].
    • (2014) Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol , vol.39 , Issue.5 , pp. 1052-1058
    • Difede, J.1    Cukor, J.2    Wyka, K.3    Olden, M.4    Hoffman, H.5    Lee, F.S.6
  • 21
    • 84875210974 scopus 로고    scopus 로고
    • From genes to cognition in tuberous sclerosis: implications for mTOR inhibitor-based treatment approaches
    • [May]
    • Ehninger D. From genes to cognition in tuberous sclerosis: implications for mTOR inhibitor-based treatment approaches. Neuropharmacology 2013, 68:97-105. [May].
    • (2013) Neuropharmacology , vol.68 , pp. 97-105
    • Ehninger, D.1
  • 22
    • 79651475390 scopus 로고    scopus 로고
    • Rapamycin for treating tuberous sclerosis and autism spectrum disorders
    • [Feb]
    • Ehninger D., Silva A.J. Rapamycin for treating tuberous sclerosis and autism spectrum disorders. Trends Mol Med 2011, 17(2):78-87. [Feb].
    • (2011) Trends Mol Med , vol.17 , Issue.2 , pp. 78-87
    • Ehninger, D.1    Silva, A.J.2
  • 23
    • 84862992452 scopus 로고    scopus 로고
    • The role of striatal-enriched protein tyrosine phosphatase (STEP) in cognition
    • Fitzpatrick C.J., Lombroso P.J. The role of striatal-enriched protein tyrosine phosphatase (STEP) in cognition. Front Neuroanat 2011, 5:47.
    • (2011) Front Neuroanat , vol.5 , pp. 47
    • Fitzpatrick, C.J.1    Lombroso, P.J.2
  • 25
    • 84866703056 scopus 로고    scopus 로고
    • D-cycloserine: an evolving role in learning and neuroplasticity in schizophrenia
    • [Sep]
    • Goff D.C. D-cycloserine: an evolving role in learning and neuroplasticity in schizophrenia. Schizophr Bull 2012, 38(5):936-941. [Sep].
    • (2012) Schizophr Bull , vol.38 , Issue.5 , pp. 936-941
    • Goff, D.C.1
  • 26
    • 56049099989 scopus 로고    scopus 로고
    • Once-weekly D-cycloserine effects on negative symptoms and cognition in schizophrenia: an exploratory study
    • [Dec]
    • Goff D.C., Cather C., Gottlieb J.D., Evins A.E., Walsh J., Raeke L., et al. Once-weekly D-cycloserine effects on negative symptoms and cognition in schizophrenia: an exploratory study. Schizophr Res 2008, 106(2-3):320-327. [Dec].
    • (2008) Schizophr Res , vol.106 , Issue.2-3 , pp. 320-327
    • Goff, D.C.1    Cather, C.2    Gottlieb, J.D.3    Evins, A.E.4    Walsh, J.5    Raeke, L.6
  • 27
    • 70349136132 scopus 로고    scopus 로고
    • Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia
    • [Oct]
    • Halene T.B., Ehrlichman R.S., Liang Y., Christian E.P., Jonak G.J., Gur T.L., et al. Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia. Genes Brain Behav 2009, 8(7):661-675. [Oct].
    • (2009) Genes Brain Behav , vol.8 , Issue.7 , pp. 661-675
    • Halene, T.B.1    Ehrlichman, R.S.2    Liang, Y.3    Christian, E.P.4    Jonak, G.J.5    Gur, T.L.6
  • 28
    • 75749114797 scopus 로고    scopus 로고
    • MTOR signaling: at the crossroads of plasticity, memory and disease
    • [Feb]
    • Hoeffer C.A., Klann E. mTOR signaling: at the crossroads of plasticity, memory and disease. Trends Neurosci 2010, 33(2):67-75. [Feb].
    • (2010) Trends Neurosci , vol.33 , Issue.2 , pp. 67-75
    • Hoeffer, C.A.1    Klann, E.2
  • 29
    • 33846444928 scopus 로고    scopus 로고
    • The cationic amino acid transporters CAT1 and CAT3 mediate NMDA receptor activation-dependent changes in elaboration of neuronal processes via the mammalian target of rapamycin mTOR pathway
    • [Jan 17]
    • Huang Y., Kang B.N., Tian J., Liu Y., Luo H.R., Hester L., et al. The cationic amino acid transporters CAT1 and CAT3 mediate NMDA receptor activation-dependent changes in elaboration of neuronal processes via the mammalian target of rapamycin mTOR pathway. J Neurosci 2007, 27(3):449-458. [Jan 17].
    • (2007) J Neurosci , vol.27 , Issue.3 , pp. 449-458
    • Huang, Y.1    Kang, B.N.2    Tian, J.3    Liu, Y.4    Luo, H.R.5    Hester, L.6
  • 30
    • 78650308610 scopus 로고    scopus 로고
    • D-serine improves dimensions of the sociability deficit of the genetically-inbred Balb/c mouse strain
    • [Jan 15]
    • Jacome L.F., Burket J.A., Herndon A.L., Cannon W.R., Deutsch S.I. D-serine improves dimensions of the sociability deficit of the genetically-inbred Balb/c mouse strain. Brain Res Bull 2011, 84(1):12-16. [Jan 15].
    • (2011) Brain Res Bull , vol.84 , Issue.1 , pp. 12-16
    • Jacome, L.F.1    Burket, J.A.2    Herndon, A.L.3    Cannon, W.R.4    Deutsch, S.I.5
  • 31
    • 79957840285 scopus 로고    scopus 로고
    • D-Cycloserine enhances social exploration in the Balb/c mouse
    • [May 30]
    • Jacome L.F., Burket J.A., Herndon A.L., Deutsch S.I. D-Cycloserine enhances social exploration in the Balb/c mouse. Brain Res Bull 2011, 85(3-4):141-144. [May 30].
    • (2011) Brain Res Bull , vol.85 , Issue.3-4 , pp. 141-144
    • Jacome, L.F.1    Burket, J.A.2    Herndon, A.L.3    Deutsch, S.I.4
  • 32
    • 83355175807 scopus 로고    scopus 로고
    • Genetically inbred Balb/c mice differ from outbred Swiss Webster mice on discrete measures of sociability: relevance to a genetic mouse model of autism spectrum disorders
    • Jacome L.F., Burket J.A., Herndon A.L., Deutsch S.I. Genetically inbred Balb/c mice differ from outbred Swiss Webster mice on discrete measures of sociability: relevance to a genetic mouse model of autism spectrum disorders. Autism Res 2011, 4(6):393-400.
    • (2011) Autism Res , vol.4 , Issue.6 , pp. 393-400
    • Jacome, L.F.1    Burket, J.A.2    Herndon, A.L.3    Deutsch, S.I.4
  • 34
    • 84923362559 scopus 로고    scopus 로고
    • Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1
    • Kim E., Wang Y., Kim S.-J., Bornhorst M., Jecrois E.S., Anthony T.E., et al. Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1. eLife 2015, 4.
    • (2015) eLife , vol.4
    • Kim, E.1    Wang, Y.2    Kim, S.-J.3    Bornhorst, M.4    Jecrois, E.S.5    Anthony, T.E.6
  • 35
    • 51249083462 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia
    • [Oct]
    • Labrie V., Lipina T., Roder J.C. Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia. Psychopharmacology (Berl) 2008, 200(2):217-230. [Oct].
    • (2008) Psychopharmacology (Berl) , vol.200 , Issue.2 , pp. 217-230
    • Labrie, V.1    Lipina, T.2    Roder, J.C.3
  • 36
    • 65249140471 scopus 로고    scopus 로고
    • The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders
    • [Apr]
    • Levitt P., Campbell D.B. The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders. J Clin Invest 2009, 119(4):747-754. [Apr].
    • (2009) J Clin Invest , vol.119 , Issue.4 , pp. 747-754
    • Levitt, P.1    Campbell, D.B.2
  • 37
    • 0027986609 scopus 로고
    • D-cycloserine enhances social behaviour in individually-housed mice in the resident-intruder test
    • [Nov]
    • McAllister K.H. D-cycloserine enhances social behaviour in individually-housed mice in the resident-intruder test. Psychopharmacology (Berl) 1994, 116(3):317-325. [Nov].
    • (1994) Psychopharmacology (Berl) , vol.116 , Issue.3 , pp. 317-325
    • McAllister, K.H.1
  • 39
    • 34250626014 scopus 로고    scopus 로고
    • A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival
    • [May 23]
    • Meikle L., Talos D.M., Onda H., Pollizzi K., Rotenberg A., Sahin M., et al. A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival. J Neurosci 2007, 27(21):5546-5558. [May 23].
    • (2007) J Neurosci , vol.27 , Issue.21 , pp. 5546-5558
    • Meikle, L.1    Talos, D.M.2    Onda, H.3    Pollizzi, K.4    Rotenberg, A.5    Sahin, M.6
  • 40
    • 45849110311 scopus 로고    scopus 로고
    • Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function
    • [May 21]
    • Meikle L., Pollizzi K., Egnor A., Kramvis I., Lane H., Sahin M., et al. Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function. J Neurosci 2008, 28(21):5422-5432. [May 21].
    • (2008) J Neurosci , vol.28 , Issue.21 , pp. 5422-5432
    • Meikle, L.1    Pollizzi, K.2    Egnor, A.3    Kramvis, I.4    Lane, H.5    Sahin, M.6
  • 41
    • 17744399498 scopus 로고    scopus 로고
    • N-Methyl-D-aspartate receptors as a target for improved antipsychotic agents: novel insights and clinical perspectives
    • [Apr]
    • Millan M.J. N-Methyl-D-aspartate receptors as a target for improved antipsychotic agents: novel insights and clinical perspectives. Psychopharmacology (Berl) 2005, 179(1):30-53. [Apr].
    • (2005) Psychopharmacology (Berl) , vol.179 , Issue.1 , pp. 30-53
    • Millan, M.J.1
  • 42
    • 84899858579 scopus 로고    scopus 로고
    • Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment
    • [May]
    • Millan M.J., Fone K., Steckler T., Horan W.P. Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment. Eur Neuropsychopharmacol J Eur Coll Neuropsychopharmacol 2014, 24(5):645-692. [May].
    • (2014) Eur Neuropsychopharmacol J Eur Coll Neuropsychopharmacol , vol.24 , Issue.5 , pp. 645-692
    • Millan, M.J.1    Fone, K.2    Steckler, T.3    Horan, W.P.4
  • 43
    • 77954705583 scopus 로고    scopus 로고
    • NR2B-NMDA receptor-mediated increases in intracellular Ca2+ concentration regulate the tyrosine phosphatase, STEP, and ERK MAP kinase signaling
    • [Aug]
    • Paul S., Connor J.A. NR2B-NMDA receptor-mediated increases in intracellular Ca2+ concentration regulate the tyrosine phosphatase, STEP, and ERK MAP kinase signaling. J Neurochem 2010, 114(4):1107-1118. [Aug].
    • (2010) J Neurochem , vol.114 , Issue.4 , pp. 1107-1118
    • Paul, S.1    Connor, J.A.2
  • 44
    • 0037220735 scopus 로고    scopus 로고
    • NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling
    • [Jan]
    • Paul S., Nairn A.C., Wang P., Lombroso P.J. NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling. Nat Neurosci 2003, 6(1):34-42. [Jan].
    • (2003) Nat Neurosci , vol.6 , Issue.1 , pp. 34-42
    • Paul, S.1    Nairn, A.C.2    Wang, P.3    Lombroso, P.J.4
  • 45
    • 84867426528 scopus 로고    scopus 로고
    • Cellular and synaptic network defects in autism
    • Peça J., Feng G. Cellular and synaptic network defects in autism. Curr Opin Neurobiol 2012, 22(5):866-872.
    • (2012) Curr Opin Neurobiol , vol.22 , Issue.5 , pp. 866-872
    • Peça, J.1    Feng, G.2
  • 46
    • 84868200593 scopus 로고    scopus 로고
    • Targeted treatment trials for tuberous sclerosis and autism: no longer a dream
    • [Oct]
    • Sahin M. Targeted treatment trials for tuberous sclerosis and autism: no longer a dream. Curr Opin Neurobiol 2012, 22(5):895-901. [Oct].
    • (2012) Curr Opin Neurobiol , vol.22 , Issue.5 , pp. 895-901
    • Sahin, M.1
  • 47
    • 84897441592 scopus 로고    scopus 로고
    • Randomized placebo-controlled D-cycloserine with cognitive behavior therapy for pediatric posttraumatic stress
    • [Mar]
    • Scheeringa M.S., Weems C.F. Randomized placebo-controlled D-cycloserine with cognitive behavior therapy for pediatric posttraumatic stress. J Child Adolesc Psychopharmacol 2014, 24(2):69-77. [Mar].
    • (2014) J Child Adolesc Psychopharmacol , vol.24 , Issue.2 , pp. 69-77
    • Scheeringa, M.S.1    Weems, C.F.2
  • 50
    • 84860491069 scopus 로고    scopus 로고
    • The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway
    • Talos D.M., Sun H., Zhou X., Fitzgerald E.C., Jackson M.C., Klein P.M., et al. The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway. PLoS One 2012, 7(5):e35885.
    • (2012) PLoS One , vol.7 , Issue.5 , pp. e35885
    • Talos, D.M.1    Sun, H.2    Zhou, X.3    Fitzgerald, E.C.4    Jackson, M.C.5    Klein, P.M.6
  • 51
    • 84865508373 scopus 로고    scopus 로고
    • Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice
    • [Aug 30]
    • Tsai P.T., Hull C., Chu Y., Greene-Colozzi E., Sadowski A.R., Leech J.M., et al. Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. Nature 2012, 488(7413):647-651. [Aug 30].
    • (2012) Nature , vol.488 , Issue.7413 , pp. 647-651
    • Tsai, P.T.1    Hull, C.2    Chu, Y.3    Greene-Colozzi, E.4    Sadowski, A.R.5    Leech, J.M.6
  • 52
    • 84901333522 scopus 로고    scopus 로고
    • A trial of D-cycloserine to treat stereotypies in older adolescents and young adults with autism spectrum disorder
    • [Jun]
    • Urbano M., Okwara L., Manser P., Hartmann K., Herndon A., Deutsch S.I. A trial of D-cycloserine to treat stereotypies in older adolescents and young adults with autism spectrum disorder. Clin Neuropharmacol 2014, 37(3):69-72. [Jun].
    • (2014) Clin Neuropharmacol , vol.37 , Issue.3 , pp. 69-72
    • Urbano, M.1    Okwara, L.2    Manser, P.3    Hartmann, K.4    Herndon, A.5    Deutsch, S.I.6
  • 53
    • 84923377629 scopus 로고    scopus 로고
    • A trial of D-cycloserine to treat the social deficit in older adolescents and young adults with autism spectrum disorders
    • [Apr] (in press)
    • Urbano M.R., Okwara L., Manser P., Hartmann K., Deutsch S.I. A trial of D-cycloserine to treat the social deficit in older adolescents and young adults with autism spectrum disorders. J Neuropsychiatry Clin Neurosci 2015, [Apr] (in press).
    • (2015) J Neuropsychiatry Clin Neurosci
    • Urbano, M.R.1    Okwara, L.2    Manser, P.3    Hartmann, K.4    Deutsch, S.I.5
  • 55
    • 42449140233 scopus 로고    scopus 로고
    • Augmentation of behavior therapy with D-cycloserine for obsessive-compulsive disorder
    • [Mar. quiz 409]
    • Wilhelm S., Buhlmann U., Tolin D.F., Meunier S.A., Pearlson G.D., Reese H.E., et al. Augmentation of behavior therapy with D-cycloserine for obsessive-compulsive disorder. Am J Psychiatry 2008, 165(3):335-341. [Mar. quiz 409].
    • (2008) Am J Psychiatry , vol.165 , Issue.3 , pp. 335-341
    • Wilhelm, S.1    Buhlmann, U.2    Tolin, D.F.3    Meunier, S.A.4    Pearlson, G.D.5    Reese, H.E.6
  • 56
    • 78751697098 scopus 로고    scopus 로고
    • Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism
    • [Feb]
    • Wöhr M., Roullet F.I., Crawley J.N. Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism. Genes Brain Behav 2011, 10(1):35-43. [Feb].
    • (2011) Genes Brain Behav , vol.10 , Issue.1 , pp. 35-43
    • Wöhr, M.1    Roullet, F.I.2    Crawley, J.N.3
  • 57
    • 84862297282 scopus 로고    scopus 로고
    • Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function
    • [June 14]
    • Won H., Lee H.-R., Gee H.Y., Mah W., Kim J.-I., Lee J., et al. Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature 2012, 486(7402):261-265. [June 14].
    • (2012) Nature , vol.486 , Issue.7402 , pp. 261-265
    • Won, H.1    Lee, H.-R.2    Gee, H.Y.3    Mah, W.4    Kim, J.-I.5    Lee, J.6
  • 58
    • 36549077053 scopus 로고    scopus 로고
    • Social deficits in BTBR T+tf/J mice are unchanged by cross-fostering with C57BL/6J mothers
    • [Dec]
    • Yang M., Zhodzishsky V., Crawley J.N. Social deficits in BTBR T+tf/J mice are unchanged by cross-fostering with C57BL/6J mothers. Int J Dev Neurosci Off J Int Soc Dev Neurosci 2007, 25(8):515-521. [Dec].
    • (2007) Int J Dev Neurosci Off J Int Soc Dev Neurosci , vol.25 , Issue.8 , pp. 515-521
    • Yang, M.1    Zhodzishsky, V.2    Crawley, J.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.