MTOR Inhibition Ameliorates Cognitive and Affective Deficits Caused by Disc1 Knockdown in Adult-Born Dentate Granule Neurons

Neuron

Volumn 77, Issue 4, 2013, Pages 647-654

  Zhou, Miou ^a   Li, Weidong ^a,b,c   Huang, Shan ^a   Song, Juan ^e   Kim, Ju Young ^e   Tian, Xiaoli ^d   Kang, Eunchai ^e   Sano, Yoshitake ^a   Liu, Cindy ^e   Balaji, J ^a   Wu, Shumin ^d   Zhou, Yu ^a,f   Zhou, Ying ^b,c   Parivash, Sherveen N ^a   Ehninger, Dan ^a,g   He, Lin ^b   Song, Hongjun ^e   Ming, Guo li ^e   Silva, Alcino J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c SHANDONG MENTAL HEALTH CENTER   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^g GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; SHORT HAIRPIN RNA;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE GYRUS; DRUG APPROVAL; DRUG MECHANISM; EMOTIONAL DISORDER; FOOD AND DRUG ADMINISTRATION; GENE DISRUPTION; GENE SILENCING; GRANULE CELL; MAZE TEST; MOUSE; NERVE CELL EXCITABILITY; NEUROANATOMY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TASK PERFORMANCE;

AGING; ANIMALS; COGNITION; DENTATE GYRUS; GENE KNOCKDOWN TECHNIQUES; MICE; NERVE TISSUE PROTEINS; NEUROGENESIS; NEURONS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84874284862     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2012.12.033     Document Type: Article

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