Pharmacological inhibition of the mTOR pathway impairs hippocampal development in mice

Neuroscience Letters

Volumn 541, Issue , 2013, Pages 9-14

  Raman, Lakshmi ^a   Kong, Xiangmei ^a   Kernie, Steven G ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b New York Presbyterian Morgan Stanley Children's Hospital   (United States)

Author keywords

Dentate gyrus; MTOR; Neurogenesis; Rapamycin

Indexed keywords

BROXURIDINE; CASPASE 3; GREEN FLUORESCENT PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN DEVELOPMENT; BRAIN HYPOXIA; CELL COUNT; CELL DEATH; CELL PROLIFERATION; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE GYRUS; ENZYME INHIBITION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LONG TERM EXPOSURE; MICROGLIA; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; ASTROCYTES; DENTATE GYRUS; GREEN FLUORESCENT PROTEINS; INTERMEDIATE FILAMENT PROTEINS; MICE; MICE, TRANSGENIC; MICROGLIA; NERVE TISSUE PROTEINS; NESTIN; NEURAL STEM CELLS; NEUROGENESIS; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84876411019     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.01.045     Document Type: Article

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