-
1
-
-
85015069067
-
Controlling the double helix
-
Felsenfeld G., Groudine M. Controlling the double helix. Nature 2003, 421:448-453.
-
(2003)
Nature
, vol.421
, pp. 448-453
-
-
Felsenfeld, G.1
Groudine, M.2
-
2
-
-
78650304236
-
Charting histone modifications and the functional organization of mammalian genomes
-
Zhou V.W., Goren A., Bernstein B.E. Charting histone modifications and the functional organization of mammalian genomes. Nat Rev Genet 2011, 12:7-18.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 7-18
-
-
Zhou, V.W.1
Goren, A.2
Bernstein, B.E.3
-
3
-
-
77949874234
-
Histone variants-ancient wrap artists of the epigenome
-
Talbert P.B., Henikoff S. Histone variants-ancient wrap artists of the epigenome. Nat Rev Mol Cell Biol 2010, 11:264-275.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 264-275
-
-
Talbert, P.B.1
Henikoff, S.2
-
4
-
-
0016687530
-
Electron microscopic and biochemical evidence that chromatin structure is a repeating unit
-
Oudet P., Gross-Bellard M., Chambon P. Electron microscopic and biochemical evidence that chromatin structure is a repeating unit. Cell 1975, 4:281-300.
-
(1975)
Cell
, vol.4
, pp. 281-300
-
-
Oudet, P.1
Gross-Bellard, M.2
Chambon, P.3
-
5
-
-
84868690351
-
Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres
-
Fussner E., Strauss M., Djuric U., Li R., Ahmed K., Hart M., et al. Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres. EMBO Rep 2012, 13:992-996.
-
(2012)
EMBO Rep
, vol.13
, pp. 992-996
-
-
Fussner, E.1
Strauss, M.2
Djuric, U.3
Li, R.4
Ahmed, K.5
Hart, M.6
-
6
-
-
84866165052
-
Chromosomes without a 30-nm chromatin fiber
-
Joti Y., Hikima T., Nishino Y., Kamada F., Hihara S., Takata H., et al. Chromosomes without a 30-nm chromatin fiber. Nucleus 2012, 3:404-410.
-
(2012)
Nucleus
, vol.3
, pp. 404-410
-
-
Joti, Y.1
Hikima, T.2
Nishino, Y.3
Kamada, F.4
Hihara, S.5
Takata, H.6
-
7
-
-
84924559967
-
Chromatin fibers are formed by heterogeneous groups of nucleosomes in vivo
-
Ricci M.A., Manzo C., García-Parajo M.F., Lakadamyali M., Cosma M.P. Chromatin fibers are formed by heterogeneous groups of nucleosomes in vivo. Cell 2015, 160:1145-1158.
-
(2015)
Cell
, vol.160
, pp. 1145-1158
-
-
Ricci, M.A.1
Manzo, C.2
García-Parajo, M.F.3
Lakadamyali, M.4
Cosma, M.P.5
-
8
-
-
84902212007
-
The 3D genome in transcriptional regulation and pluripotency
-
Gorkin D.U., Leung D., Ren B. The 3D genome in transcriptional regulation and pluripotency. Cell Stem Cell 2014, 14:762-775.
-
(2014)
Cell Stem Cell
, vol.14
, pp. 762-775
-
-
Gorkin, D.U.1
Leung, D.2
Ren, B.3
-
9
-
-
33847077659
-
Beyond the sequence: cellular organization of genome function
-
Misteli T. Beyond the sequence: cellular organization of genome function. Cell 2007, 128:787-800.
-
(2007)
Cell
, vol.128
, pp. 787-800
-
-
Misteli, T.1
-
10
-
-
84876838711
-
The hierarchy of the 3D genome
-
Gibcus J.H., Dekker J. The hierarchy of the 3D genome. Mol Cell 2013, 49:773-782.
-
(2013)
Mol Cell
, vol.49
, pp. 773-782
-
-
Gibcus, J.H.1
Dekker, J.2
-
11
-
-
84926189204
-
Three-dimensional genome architecture: players and mechanisms
-
Pombo A., Dillon N. Three-dimensional genome architecture: players and mechanisms. Nat Rev Mol Cell Biol 2015, 16:245-257.
-
(2015)
Nat Rev Mol Cell Biol
, vol.16
, pp. 245-257
-
-
Pombo, A.1
Dillon, N.2
-
13
-
-
41949121084
-
Recruitment to the nuclear periphery can alter expression of genes in human cells
-
Finlan L.E., Sproul D., Thomson I., Boyle S., Kerr E., Perry P., et al. Recruitment to the nuclear periphery can alter expression of genes in human cells. PLoS Genet 2008, 4:e1000039.
-
(2008)
PLoS Genet
, vol.4
, pp. e1000039
-
-
Finlan, L.E.1
Sproul, D.2
Thomson, I.3
Boyle, S.4
Kerr, E.5
Perry, P.6
-
14
-
-
84949529403
-
Perinuclear anchoring of H3K9-methylated chromatin stabilizes induced cell fate in C. elegans embryos
-
Gonzalez-Sandoval A., Towbin B.D., Kalck V., Cabianca D.S., Gaidatzis D., Hauer M.H., et al. Perinuclear anchoring of H3K9-methylated chromatin stabilizes induced cell fate in C. elegans embryos. Cell 2015, 163:1333-1347.
-
(2015)
Cell
, vol.163
, pp. 1333-1347
-
-
Gonzalez-Sandoval, A.1
Towbin, B.D.2
Kalck, V.3
Cabianca, D.S.4
Gaidatzis, D.5
Hauer, M.H.6
-
16
-
-
36849074774
-
Dynamics and interplay of nuclear architecture, genome organization, and gene expression
-
Schneider R., Grosschedl R. Dynamics and interplay of nuclear architecture, genome organization, and gene expression. Genes Dev 2007, 21:3027-3043.
-
(2007)
Genes Dev
, vol.21
, pp. 3027-3043
-
-
Schneider, R.1
Grosschedl, R.2
-
17
-
-
84865195601
-
The genome in space and time: does form always follow function? How does the spatial and temporal organization of a eukaryotic genome reflect and influence its functions?
-
Duan Z., Blau C.A. The genome in space and time: does form always follow function? How does the spatial and temporal organization of a eukaryotic genome reflect and influence its functions?. BioEssays 2012, 34:800-810.
-
(2012)
BioEssays
, vol.34
, pp. 800-810
-
-
Duan, Z.1
Blau, C.A.2
-
18
-
-
84939802036
-
Getting the genome in shape: the formation of loops, domains and compartments
-
Bouwman B.A., de Laat W. Getting the genome in shape: the formation of loops, domains and compartments. Genome Biol 2015, 16:154.
-
(2015)
Genome Biol
, vol.16
, pp. 154
-
-
Bouwman, B.A.1
de Laat, W.2
-
19
-
-
84924875394
-
The role of chromosome domains in shaping the functional genome
-
Sexton T., Cavalli G. The role of chromosome domains in shaping the functional genome. Cell 2015, 160:1049-1059.
-
(2015)
Cell
, vol.160
, pp. 1049-1059
-
-
Sexton, T.1
Cavalli, G.2
-
20
-
-
77957932111
-
Genomics tools for unraveling chromosome architecture
-
van Steensel B., Dekker J. Genomics tools for unraveling chromosome architecture. Nat Biotechnol 2010, 28:1089-1095.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 1089-1095
-
-
van Steensel, B.1
Dekker, J.2
-
21
-
-
84855297335
-
A decade of 3C technologies: insights into nuclear organization
-
de Wit E., de Laat W. A decade of 3C technologies: insights into nuclear organization. Genes Dev 2012, 26:11-24.
-
(2012)
Genes Dev
, vol.26
, pp. 11-24
-
-
de Wit, E.1
de Laat, W.2
-
22
-
-
84879264708
-
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
-
Gaj T., Gersbach C.A., Barbas C.F. ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol 2013, 31:397-405.
-
(2013)
Trends Biotechnol
, vol.31
, pp. 397-405
-
-
Gaj, T.1
Gersbach, C.A.2
Barbas, C.F.3
-
23
-
-
84937513337
-
Unraveling the 3D genome: genomics tools for multiscale exploration
-
Risca V.I., Greenleaf W.J. Unraveling the 3D genome: genomics tools for multiscale exploration. Trends Genet 2015, 31:357-372.
-
(2015)
Trends Genet
, vol.31
, pp. 357-372
-
-
Risca, V.I.1
Greenleaf, W.J.2
-
24
-
-
80051582296
-
Electron microscopy and atomic force microscopy studies of chromatin and metaphase chromosome structure
-
Daban J.R. Electron microscopy and atomic force microscopy studies of chromatin and metaphase chromosome structure. Micron 2011, 42:733-750.
-
(2011)
Micron
, vol.42
, pp. 733-750
-
-
Daban, J.R.1
-
25
-
-
84855219582
-
A view of the chromatin landscape
-
Rapkin L.M., Anchel D.R., Li R., Bazett-Jones D.P. A view of the chromatin landscape. Micron 2012, 43:150-158.
-
(2012)
Micron
, vol.43
, pp. 150-158
-
-
Rapkin, L.M.1
Anchel, D.R.2
Li, R.3
Bazett-Jones, D.P.4
-
26
-
-
78650512639
-
Breaking the diffraction barrier: super-resolution imaging of cells
-
Huang B., Babcock H., Zhuang X. Breaking the diffraction barrier: super-resolution imaging of cells. Cell 2010, 143:1047-1058.
-
(2010)
Cell
, vol.143
, pp. 1047-1058
-
-
Huang, B.1
Babcock, H.2
Zhuang, X.3
-
27
-
-
84941242227
-
The revolution will not be crystallized: a new method sweeps through structural biology
-
Callaway E. The revolution will not be crystallized: a new method sweeps through structural biology. Nature 2015, 525:172-174.
-
(2015)
Nature
, vol.525
, pp. 172-174
-
-
Callaway, E.1
-
28
-
-
84899570718
-
Cryo-EM study of the chromatin fiber reveals a double helix twisted by tetranucleosomal units
-
Song F., Chen P., Sun D., Wang M., Dong L., Liang D., et al. Cryo-EM study of the chromatin fiber reveals a double helix twisted by tetranucleosomal units. Science 2014, 344:376-380.
-
(2014)
Science
, vol.344
, pp. 376-380
-
-
Song, F.1
Chen, P.2
Sun, D.3
Wang, M.4
Dong, L.5
Liang, D.6
-
29
-
-
0020158239
-
Immunological method for mapping genes on Drosophila polytene chromosomes
-
Langer-Safer P.R., Levine M., Ward D.C. Immunological method for mapping genes on Drosophila polytene chromosomes. Proc Natl Acad Sci U S A 1982, 79:4381-4385.
-
(1982)
Proc Natl Acad Sci U S A
, vol.79
, pp. 4381-4385
-
-
Langer-Safer, P.R.1
Levine, M.2
Ward, D.C.3
-
30
-
-
0033672197
-
Visualization of gene activity in living cells
-
Tsukamoto T., Hashiguchi N., Janicki S.M., Tumbar T., Belmont A.S., Spector D.L. Visualization of gene activity in living cells. Nat Cell Biol 2000, 2:871-878.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 871-878
-
-
Tsukamoto, T.1
Hashiguchi, N.2
Janicki, S.M.3
Tumbar, T.4
Belmont, A.S.5
Spector, D.L.6
-
31
-
-
85052429852
-
Multicolor 3D fluorescence in situ hybridization for imaging interphase chromosomes
-
Cremer M., Grasser F., Lanctot C., Muller S., Neusser M., Zinner R., et al. Multicolor 3D fluorescence in situ hybridization for imaging interphase chromosomes. Methods Mol Biol 2008, 463:205-239.
-
(2008)
Methods Mol Biol
, vol.463
, pp. 205-239
-
-
Cremer, M.1
Grasser, F.2
Lanctot, C.3
Muller, S.4
Neusser, M.5
Zinner, R.6
-
32
-
-
43149084361
-
Changes in chromosome organization during PHA-activation of resting human lymphocytes measured by cryo-FISH
-
Branco M.R., Branco T., Ramirez F., Pombo A. Changes in chromosome organization during PHA-activation of resting human lymphocytes measured by cryo-FISH. Chromosome Res 2008, 16:413-426.
-
(2008)
Chromosome Res
, vol.16
, pp. 413-426
-
-
Branco, M.R.1
Branco, T.2
Ramirez, F.3
Pombo, A.4
-
33
-
-
84871822966
-
Versatile design and synthesis platform for visualizing genomes with Oligopaint FISH probes
-
Beliveau B.J., Joyce E.F., Apostolopoulos N., Yilmaz F., Fonseka C.Y., McCole R.B., et al. Versatile design and synthesis platform for visualizing genomes with Oligopaint FISH probes. Proc Natl Acad Sci U S A 2012, 109:21301-21306.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 21301-21306
-
-
Beliveau, B.J.1
Joyce, E.F.2
Apostolopoulos, N.3
Yilmaz, F.4
Fonseka, C.Y.5
McCole, R.B.6
-
34
-
-
84939489844
-
Identification of gene positioning factors using high-throughput imaging mapping
-
Shachar S., Voss T.C., Pegoraro G., Sciascia N., Misteli T. Identification of gene positioning factors using high-throughput imaging mapping. Cell 2015, 162:911-923.
-
(2015)
Cell
, vol.162
, pp. 911-923
-
-
Shachar, S.1
Voss, T.C.2
Pegoraro, G.3
Sciascia, N.4
Misteli, T.5
-
35
-
-
84948461391
-
A high-resolution imaging approach to investigate chromatin architecture in complex tissues
-
Linhoff M.W., Garg S.K., Mandel G. A high-resolution imaging approach to investigate chromatin architecture in complex tissues. Cell 2015, 163:246-255.
-
(2015)
Cell
, vol.163
, pp. 246-255
-
-
Linhoff, M.W.1
Garg, S.K.2
Mandel, G.3
-
37
-
-
84943200169
-
Advanced microscopy methods for visualizing chromatin structure
-
Lakadamyali M., Cosma M.P. Advanced microscopy methods for visualizing chromatin structure. FEBS Lett 2015, 589:3023-3030.
-
(2015)
FEBS Lett
, vol.589
, pp. 3023-3030
-
-
Lakadamyali, M.1
Cosma, M.P.2
-
38
-
-
84859845974
-
The potential of 3D-FISH and super-resolution structured illumination microscopy for studies of 3D nuclear architecture: 3D structured illumination microscopy of defined chromosomal structures visualized by 3D (immuno)-FISH opens new perspectives for studies of nuclear architecture
-
Markaki Y., Smeets D., Fiedler S., Schmid V.J., Schermelleh L., Cremer T., et al. The potential of 3D-FISH and super-resolution structured illumination microscopy for studies of 3D nuclear architecture: 3D structured illumination microscopy of defined chromosomal structures visualized by 3D (immuno)-FISH opens new perspectives for studies of nuclear architecture. BioEssays 2012, 34:412-426.
-
(2012)
BioEssays
, vol.34
, pp. 412-426
-
-
Markaki, Y.1
Smeets, D.2
Fiedler, S.3
Schmid, V.J.4
Schermelleh, L.5
Cremer, T.6
-
39
-
-
45549091077
-
Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy
-
Schermelleh L., Carlton P.M., Haase S., Shao L., Winoto L., Kner P., et al. Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy. Science 2008, 320:1332-1336.
-
(2008)
Science
, vol.320
, pp. 1332-1336
-
-
Schermelleh, L.1
Carlton, P.M.2
Haase, S.3
Shao, L.4
Winoto, L.5
Kner, P.6
-
40
-
-
80052643394
-
Chromosome organization by a nucleoid-associated protein in live bacteria
-
Wang W., Li G.W., Chen C., Xie X.S., Zhuang X. Chromosome organization by a nucleoid-associated protein in live bacteria. Science 2011, 333:1445-1449.
-
(2011)
Science
, vol.333
, pp. 1445-1449
-
-
Wang, W.1
Li, G.W.2
Chen, C.3
Xie, X.S.4
Zhuang, X.5
-
41
-
-
84929673223
-
Imaging live-cell dynamics and structure at the single-molecule level
-
Liu Z., Lavis L.D., Betzig E. Imaging live-cell dynamics and structure at the single-molecule level. Mol Cell 2015, 58:644-659.
-
(2015)
Mol Cell
, vol.58
, pp. 644-659
-
-
Liu, Z.1
Lavis, L.D.2
Betzig, E.3
-
43
-
-
84894063115
-
Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system
-
Chen B., Gilbert L.A., Cimini B.A., Schnitzbauer J., Zhang W., Li G.W., et al. Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell 2013, 155:1479-1491.
-
(2013)
Cell
, vol.155
, pp. 1479-1491
-
-
Chen, B.1
Gilbert, L.A.2
Cimini, B.A.3
Schnitzbauer, J.4
Zhang, W.5
Li, G.W.6
-
44
-
-
84946919064
-
Dynamics of CRISPR-Cas9 genome interrogation in living cells
-
Knight S.C., Xie L., Deng W., Guglielmi B., Witkowsky L.B., Bosanac L., et al. Dynamics of CRISPR-Cas9 genome interrogation in living cells. Science 2015, 350:823-826.
-
(2015)
Science
, vol.350
, pp. 823-826
-
-
Knight, S.C.1
Xie, L.2
Deng, W.3
Guglielmi, B.4
Witkowsky, L.B.5
Bosanac, L.6
-
45
-
-
84869457261
-
The expanding scope of DNA sequencing
-
Shendure J., Lieberman Aiden E. The expanding scope of DNA sequencing. Nat Biotechnol 2012, 30:1084-1094.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 1084-1094
-
-
Shendure, J.1
Lieberman Aiden, E.2
-
46
-
-
84940517744
-
Analysis methods for studying the 3D architecture of the genome
-
Ay F., Noble W.S. Analysis methods for studying the 3D architecture of the genome. Genome Biol 2015, 16:183.
-
(2015)
Genome Biol
, vol.16
, pp. 183
-
-
Ay, F.1
Noble, W.S.2
-
47
-
-
70349312354
-
ChIP-seq: advantages and challenges of a maturing technology
-
Park P.J. ChIP-seq: advantages and challenges of a maturing technology. Nat Rev Genet 2009, 10:669-680.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 669-680
-
-
Park, P.J.1
-
48
-
-
0034007256
-
Identification of in vivo DNA targets of chromatin proteins using tethered dam methyltransferase
-
van Steensel B., Henikoff S. Identification of in vivo DNA targets of chromatin proteins using tethered dam methyltransferase. Nat Biotechnol 2000, 18:424-428.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 424-428
-
-
van Steensel, B.1
Henikoff, S.2
-
49
-
-
77950375276
-
Initial genomics of the human nucleolus
-
Nemeth A., Conesa A., Santoyo-Lopez J., Medina I., Montaner D., Peterfia B., et al. Initial genomics of the human nucleolus. PLoS Genet 2010, 6:e1000889.
-
(2010)
PLoS Genet
, vol.6
, pp. e1000889
-
-
Nemeth, A.1
Conesa, A.2
Santoyo-Lopez, J.3
Medina, I.4
Montaner, D.5
Peterfia, B.6
-
50
-
-
45149084413
-
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
-
Guelen L., Pagie L., Brasset E., Meuleman W., Faza M.B., Talhout W., et al. Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions. Nature 2008, 453:948-951.
-
(2008)
Nature
, vol.453
, pp. 948-951
-
-
Guelen, L.1
Pagie, L.2
Brasset, E.3
Meuleman, W.4
Faza, M.B.5
Talhout, W.6
-
51
-
-
84875703872
-
Single-cell dynamics of genome-nuclear lamina interactions
-
Kind J., Pagie L., Ortabozkoyun H., Boyle S., de Vries S.S., Janssen H., et al. Single-cell dynamics of genome-nuclear lamina interactions. Cell 2013, 153:178-192.
-
(2013)
Cell
, vol.153
, pp. 178-192
-
-
Kind, J.1
Pagie, L.2
Ortabozkoyun, H.3
Boyle, S.4
de Vries, S.S.5
Janssen, H.6
-
52
-
-
84948587544
-
Genome-wide maps of nuclear lamina interactions in single human cells
-
Kind J., Pagie L., de Vries S.S., Nahidiazar L., Dey S.S., Bienko M., et al. Genome-wide maps of nuclear lamina interactions in single human cells. Cell 2015, 163:134-147.
-
(2015)
Cell
, vol.163
, pp. 134-147
-
-
Kind, J.1
Pagie, L.2
de Vries, S.S.3
Nahidiazar, L.4
Dey, S.S.5
Bienko, M.6
-
53
-
-
80054756754
-
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions
-
Chu C., Qu K., Zhong F.L., Artandi S.E., Chang H.Y. Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. Mol Cell 2011, 44:667-678.
-
(2011)
Mol Cell
, vol.44
, pp. 667-678
-
-
Chu, C.1
Qu, K.2
Zhong, F.L.3
Artandi, S.E.4
Chang, H.Y.5
-
54
-
-
84890549512
-
High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation
-
Simon M.D., Pinter S.F., Fang R., Sarma K., Rutenberg-Schoenberg M., Bowman S.K., et al. High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation. Nature 2013, 504:465-469.
-
(2013)
Nature
, vol.504
, pp. 465-469
-
-
Simon, M.D.1
Pinter, S.F.2
Fang, R.3
Sarma, K.4
Rutenberg-Schoenberg, M.5
Bowman, S.K.6
-
55
-
-
84879642373
-
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome
-
Engreitz J.M., Pandya-Jones A., McDonel P., Shishkin A., Sirokman K., Surka C., et al. The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome. Science 2013, 341:1237973.
-
(2013)
Science
, vol.341
, pp. 1237973
-
-
Engreitz, J.M.1
Pandya-Jones, A.2
McDonel, P.3
Shishkin, A.4
Sirokman, K.5
Surka, C.6
-
56
-
-
84906322449
-
Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification
-
Quinn J.J., Ilik I.A., Qu K., Georgiev P., Chu C., Akhtar A., et al. Revealing long noncoding RNA architecture and functions using domain-specific chromatin isolation by RNA purification. Nat Biotechnol 2014, 32:933-940.
-
(2014)
Nat Biotechnol
, vol.32
, pp. 933-940
-
-
Quinn, J.J.1
Ilik, I.A.2
Qu, K.3
Georgiev, P.4
Chu, C.5
Akhtar, A.6
-
57
-
-
0037083376
-
Capturing chromosome conformation
-
Dekker J., Rippe K., Dekker M., Kleckner N. Capturing chromosome conformation. Science 2002, 295:1306-1311.
-
(2002)
Science
, vol.295
, pp. 1306-1311
-
-
Dekker, J.1
Rippe, K.2
Dekker, M.3
Kleckner, N.4
-
58
-
-
70349873824
-
Comprehensive mapping of long-range interactions reveals folding principles of the human genome
-
Lieberman-Aiden E., van Berkum N.L., Williams L., Imakaev M., Ragoczy T., Telling A., et al. Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science 2009, 326:289-293.
-
(2009)
Science
, vol.326
, pp. 289-293
-
-
Lieberman-Aiden, E.1
van Berkum, N.L.2
Williams, L.3
Imakaev, M.4
Ragoczy, T.5
Telling, A.6
-
59
-
-
84862917808
-
Genome architectures revealed by tethered chromosome conformation capture and population-based modeling
-
Kalhor R., Tjong H., Jayathilaka N., Alber F., Chen L. Genome architectures revealed by tethered chromosome conformation capture and population-based modeling. Nat Biotechnol 2012, 30:90-98.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 90-98
-
-
Kalhor, R.1
Tjong, H.2
Jayathilaka, N.3
Alber, F.4
Chen, L.5
-
60
-
-
84885617426
-
Single-cell Hi-C reveals cell-to-cell variability in chromosome structure
-
Nagano T., Lubling Y., Stevens T.J., Schoenfelder S., Yaffe E., Dean W., et al. Single-cell Hi-C reveals cell-to-cell variability in chromosome structure. Nature 2013, 502:59-64.
-
(2013)
Nature
, vol.502
, pp. 59-64
-
-
Nagano, T.1
Lubling, Y.2
Stevens, T.J.3
Schoenfelder, S.4
Yaffe, E.5
Dean, W.6
-
61
-
-
84926177361
-
Fine-scale chromatin interaction maps reveal the cis-regulatory landscape of human lincRNA genes
-
Ma W., Ay F., Lee C., Gulsoy G., Deng X., Cook S., et al. Fine-scale chromatin interaction maps reveal the cis-regulatory landscape of human lincRNA genes. Nat Methods 2015, 12:71-78.
-
(2015)
Nat Methods
, vol.12
, pp. 71-78
-
-
Ma, W.1
Ay, F.2
Lee, C.3
Gulsoy, G.4
Deng, X.5
Cook, S.6
-
62
-
-
84919949716
-
A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping
-
Rao S.S., Huntley M.H., Durand N.C., Stamenova E.K., Bochkov I.D., Robinson J.T., et al. A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping. Cell 2014, 159:1665-1680.
-
(2014)
Cell
, vol.159
, pp. 1665-1680
-
-
Rao, S.S.1
Huntley, M.H.2
Durand, N.C.3
Stamenova, E.K.4
Bochkov, I.D.5
Robinson, J.T.6
-
63
-
-
84939483651
-
Bipartite structure of the inactive mouse X chromosome
-
Deng X., Ma W., Ramani V., Hill A., Yang F., Ay F., et al. Bipartite structure of the inactive mouse X chromosome. Genome Biol 2015, 16:152.
-
(2015)
Genome Biol
, vol.16
, pp. 152
-
-
Deng, X.1
Ma, W.2
Ramani, V.3
Hill, A.4
Yang, F.5
Ay, F.6
-
64
-
-
84934435162
-
Mapping nucleosome resolution chromosome folding in yeast by Micro-C
-
Hsieh T.H., Weiner A., Lajoie B., Dekker J., Friedman N., Rando O.J. Mapping nucleosome resolution chromosome folding in yeast by Micro-C. Cell 2015, 162:108-119.
-
(2015)
Cell
, vol.162
, pp. 108-119
-
-
Hsieh, T.H.1
Weiner, A.2
Lajoie, B.3
Dekker, J.4
Friedman, N.5
Rando, O.J.6
-
65
-
-
11244328520
-
Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome
-
Horike S., Cai S., Miyano M., Cheng J.F., Kohwi-Shigematsu T. Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Nat Genet 2005, 37:31-40.
-
(2005)
Nat Genet
, vol.37
, pp. 31-40
-
-
Horike, S.1
Cai, S.2
Miyano, M.3
Cheng, J.F.4
Kohwi-Shigematsu, T.5
-
66
-
-
33750212321
-
Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C)
-
Simonis M., Klous P., Splinter E., Moshkin Y., Willemsen R., de Wit E., et al. Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C). Nat Genet 2006, 38:1348-1354.
-
(2006)
Nat Genet
, vol.38
, pp. 1348-1354
-
-
Simonis, M.1
Klous, P.2
Splinter, E.3
Moshkin, Y.4
Willemsen, R.5
de Wit, E.6
-
67
-
-
33750203582
-
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions
-
Zhao Z., Tavoosidana G., Sjolinder M., Gondor A., Mariano P., Wang S., et al. Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions. Nat Genet 2006, 38:1341-1347.
-
(2006)
Nat Genet
, vol.38
, pp. 1341-1347
-
-
Zhao, Z.1
Tavoosidana, G.2
Sjolinder, M.3
Gondor, A.4
Mariano, P.5
Wang, S.6
-
68
-
-
73349090560
-
Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells
-
Schoenfelder S., Sexton T., Chakalova L., Cope N.F., Horton A., Andrews S., et al. Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells. Nat Genet 2010, 42:53-61.
-
(2010)
Nat Genet
, vol.42
, pp. 53-61
-
-
Schoenfelder, S.1
Sexton, T.2
Chakalova, L.3
Cope, N.F.4
Horton, A.5
Andrews, S.6
-
69
-
-
33749400168
-
Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements
-
Dostie J., Richmond T.A., Arnaout R.A., Selzer R.R., Lee W.L., Honan T.A., et al. Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elements. Genome Res 2006, 16:1299-1309.
-
(2006)
Genome Res
, vol.16
, pp. 1299-1309
-
-
Dostie, J.1
Richmond, T.A.2
Arnaout, R.A.3
Selzer, R.R.4
Lee, W.L.5
Honan, T.A.6
-
70
-
-
70449103609
-
An oestrogen-receptor-alpha-bound human chromatin interactome
-
Fullwood M.J., Liu M.H., Pan Y.F., Liu J., Xu H., Mohamed Y.B., et al. An oestrogen-receptor-alpha-bound human chromatin interactome. Nature 2009, 462:58-64.
-
(2009)
Nature
, vol.462
, pp. 58-64
-
-
Fullwood, M.J.1
Liu, M.H.2
Pan, Y.F.3
Liu, J.4
Xu, H.5
Mohamed, Y.B.6
-
71
-
-
84951567954
-
CTCF-mediated human 3D genome architecture reveals chromatin topology for transcription
-
Tang Z., Luo O.J., Li X., Zheng M., Zhu J.J., Szalaj P., et al. CTCF-mediated human 3D genome architecture reveals chromatin topology for transcription. Cell 2015, 163:1611-1627.
-
(2015)
Cell
, vol.163
, pp. 1611-1627
-
-
Tang, Z.1
Luo, O.J.2
Li, X.3
Zheng, M.4
Zhu, J.J.5
Szalaj, P.6
-
72
-
-
84895832107
-
Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment
-
Hughes J.R., Roberts N., McGowan S., Hay D., Giannoulatou E., Lynch M., et al. Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment. Nat Genet 2014, 46:205-212.
-
(2014)
Nat Genet
, vol.46
, pp. 205-212
-
-
Hughes, J.R.1
Roberts, N.2
McGowan, S.3
Hay, D.4
Giannoulatou, E.5
Lynch, M.6
-
73
-
-
84930092058
-
Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C
-
Mifsud B., Tavares-Cadete F., Young A.N., Sugar R., Schoenfelder S., Ferreira L., et al. Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C. Nat Genet 2015, 47:598-606.
-
(2015)
Nat Genet
, vol.47
, pp. 598-606
-
-
Mifsud, B.1
Tavares-Cadete, F.2
Young, A.N.3
Sugar, R.4
Schoenfelder, S.5
Ferreira, L.6
-
74
-
-
84887322004
-
High-resolution mapping of the spatial organization of a bacterial chromosome
-
Le T.B., Imakaev M.V., Mirny L.A., Laub M.T. High-resolution mapping of the spatial organization of a bacterial chromosome. Science 2013, 342:731-734.
-
(2013)
Science
, vol.342
, pp. 731-734
-
-
Le, T.B.1
Imakaev, M.V.2
Mirny, L.A.3
Laub, M.T.4
-
75
-
-
84904548768
-
Species-level deconvolution of metagenome assemblies with Hi-C-based contact probability maps
-
Burton J.N., Liachko I., Dunham M.J., Shendure J. Species-level deconvolution of metagenome assemblies with Hi-C-based contact probability maps. G3 (Bethesda) 2014, 4:1339-1346.
-
(2014)
G3 (Bethesda)
, vol.4
, pp. 1339-1346
-
-
Burton, J.N.1
Liachko, I.2
Dunham, M.J.3
Shendure, J.4
-
76
-
-
84939550260
-
Condensin- and replication-mediated bacterial chromosome folding and origin condensation revealed by Hi-C and Super-resolution imaging
-
Marbouty M., Le Gall A., Cattoni D.I., Cournac A., Koh A., Fiche J.B., et al. Condensin- and replication-mediated bacterial chromosome folding and origin condensation revealed by Hi-C and Super-resolution imaging. Mol Cell 2015, 59:588-602.
-
(2015)
Mol Cell
, vol.59
, pp. 588-602
-
-
Marbouty, M.1
Le Gall, A.2
Cattoni, D.I.3
Cournac, A.4
Koh, A.5
Fiche, J.B.6
-
77
-
-
77952744854
-
A three-dimensional model of the yeast genome
-
Duan Z., Andronescu M., Schutz K., McIlwain S., Kim Y.J., Lee C., et al. A three-dimensional model of the yeast genome. Nature 2010, 465:363-367.
-
(2010)
Nature
, vol.465
, pp. 363-367
-
-
Duan, Z.1
Andronescu, M.2
Schutz, K.3
McIlwain, S.4
Kim, Y.J.5
Lee, C.6
-
78
-
-
84923169410
-
Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe
-
Mizuguchi T., Fudenberg G., Mehta S., Belton J.M., Taneja N., Folco H.D., et al. Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe. Nature 2014, 516:432-435.
-
(2014)
Nature
, vol.516
, pp. 432-435
-
-
Mizuguchi, T.1
Fudenberg, G.2
Mehta, S.3
Belton, J.M.4
Taneja, N.5
Folco, H.D.6
-
79
-
-
84900465317
-
Three-dimensional modeling of the P. falciparum genome during the erythrocytic cycle reveals a strong connection between genome architecture and gene expression
-
Ay F., Bunnik E.M., Varoquaux N., Bol S.M., Prudhomme J., Vert J.P., et al. Three-dimensional modeling of the P. falciparum genome during the erythrocytic cycle reveals a strong connection between genome architecture and gene expression. Genome Res 2014, 24:974-988.
-
(2014)
Genome Res
, vol.24
, pp. 974-988
-
-
Ay, F.1
Bunnik, E.M.2
Varoquaux, N.3
Bol, S.M.4
Prudhomme, J.5
Vert, J.P.6
-
80
-
-
84921685857
-
Genome-wide Hi-C analyses in wild-type and mutants reveal high-resolution chromatin interactions in Arabidopsis
-
Feng S., Cokus S.J., Schubert V., Zhai J., Pellegrini M., Jacobsen S.E. Genome-wide Hi-C analyses in wild-type and mutants reveal high-resolution chromatin interactions in Arabidopsis. Mol Cell 2014, 55:694-707.
-
(2014)
Mol Cell
, vol.55
, pp. 694-707
-
-
Feng, S.1
Cokus, S.J.2
Schubert, V.3
Zhai, J.4
Pellegrini, M.5
Jacobsen, S.E.6
-
81
-
-
84921643810
-
Hi-C analysis in Arabidopsis identifies the KNOT, a structure with similarities to the flamenco locus of Drosophila
-
Grob S., Schmid M.W., Grossniklaus U. Hi-C analysis in Arabidopsis identifies the KNOT, a structure with similarities to the flamenco locus of Drosophila. Mol Cell 2014, 55:678-693.
-
(2014)
Mol Cell
, vol.55
, pp. 678-693
-
-
Grob, S.1
Schmid, M.W.2
Grossniklaus, U.3
-
82
-
-
84936945257
-
Condensin-driven remodelling of X chromosome topology during dosage compensation
-
Crane E., Bian Q., McCord R.P., Lajoie B.R., Wheeler B.S., Ralston E.J., et al. Condensin-driven remodelling of X chromosome topology during dosage compensation. Nature 2015, 523:240-244.
-
(2015)
Nature
, vol.523
, pp. 240-244
-
-
Crane, E.1
Bian, Q.2
McCord, R.P.3
Lajoie, B.R.4
Wheeler, B.S.5
Ralston, E.J.6
-
83
-
-
84869003748
-
Gene density, transcription, and insulators contribute to the partition of the Drosophila genome into physical domains
-
Hou C., Li L., Qin Z.S., Corces V.G. Gene density, transcription, and insulators contribute to the partition of the Drosophila genome into physical domains. Mol Cell 2012, 48:471-484.
-
(2012)
Mol Cell
, vol.48
, pp. 471-484
-
-
Hou, C.1
Li, L.2
Qin, Z.S.3
Corces, V.G.4
-
84
-
-
84856747483
-
Three-dimensional folding and functional organization principles of the Drosophila genome
-
Sexton T., Yaffe E., Kenigsberg E., Bantignies F., Leblanc B., Hoichman M., et al. Three-dimensional folding and functional organization principles of the Drosophila genome. Cell 2012, 148:458-472.
-
(2012)
Cell
, vol.148
, pp. 458-472
-
-
Sexton, T.1
Yaffe, E.2
Kenigsberg, E.3
Bantignies, F.4
Leblanc, B.5
Hoichman, M.6
-
85
-
-
84861095603
-
Topological domains in mammalian genomes identified by analysis of chromatin interactions
-
Dixon J.R., Selvaraj S., Yue F., Kim A., Li Y., Shen Y., et al. Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature 2012, 485:376-380.
-
(2012)
Nature
, vol.485
, pp. 376-380
-
-
Dixon, J.R.1
Selvaraj, S.2
Yue, F.3
Kim, A.4
Li, Y.5
Shen, Y.6
-
86
-
-
84923366733
-
Chromatin architecture reorganization during stem cell differentiation
-
Dixon J.R., Jung I., Selvaraj S., Shen Y., Antosiewicz-Bourget J.E., Lee A.Y., et al. Chromatin architecture reorganization during stem cell differentiation. Nature 2015, 518:331-336.
-
(2015)
Nature
, vol.518
, pp. 331-336
-
-
Dixon, J.R.1
Jung, I.2
Selvaraj, S.3
Shen, Y.4
Antosiewicz-Bourget, J.E.5
Lee, A.Y.6
-
87
-
-
84878011578
-
Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data
-
Dekker J., Marti-Renom M.A., Mirny L.A. Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data. Nat Rev Genet 2013, 14:390-403.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 390-403
-
-
Dekker, J.1
Marti-Renom, M.A.2
Mirny, L.A.3
-
88
-
-
84946545109
-
Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state
-
Rotem A., Ram O., Shoresh N., Sperling R.A., Goren A., Weitz D.A., et al. Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state. Nat Biotechnol 2015, 33:1165-1172.
-
(2015)
Nat Biotechnol
, vol.33
, pp. 1165-1172
-
-
Rotem, A.1
Ram, O.2
Shoresh, N.3
Sperling, R.A.4
Goren, A.5
Weitz, D.A.6
-
89
-
-
84947906613
-
Single-cell Hi-C for genome-wide detection of chromatin interactions that occur simultaneously in a single cell
-
Nagano T., Lubling Y., Yaffe E., Wingett S.W., Dean W., Tanay A., et al. Single-cell Hi-C for genome-wide detection of chromatin interactions that occur simultaneously in a single cell. Nat Protoc 2015, 10:1986-2003.
-
(2015)
Nat Protoc
, vol.10
, pp. 1986-2003
-
-
Nagano, T.1
Lubling, Y.2
Yaffe, E.3
Wingett, S.W.4
Dean, W.5
Tanay, A.6
-
90
-
-
77955867185
-
Genome editing with engineered zinc finger nucleases
-
Urnov F.D., Rebar E.J., Holmes M.C., Zhang H.S., Gregory P.D. Genome editing with engineered zinc finger nucleases. Nat Rev Genet 2010, 11:636-646.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 636-646
-
-
Urnov, F.D.1
Rebar, E.J.2
Holmes, M.C.3
Zhang, H.S.4
Gregory, P.D.5
-
91
-
-
84890048526
-
Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins
-
Maeder M.L., Angstman J.F., Richardson M.E., Linder S.J., Cascio V.M., Tsai S.Q., et al. Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins. Nat Biotechnol 2013, 31:1137-1142.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 1137-1142
-
-
Maeder, M.L.1
Angstman, J.F.2
Richardson, M.E.3
Linder, S.J.4
Cascio, V.M.5
Tsai, S.Q.6
-
92
-
-
84886084801
-
Locus-specific editing of histone modifications at endogenous enhancers
-
Mendenhall E.M., Williamson K.E., Reyon D., Zou J.Y., Ram O., Joung J.K., et al. Locus-specific editing of histone modifications at endogenous enhancers. Nat Biotechnol 2013, 31:1133-1136.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 1133-1136
-
-
Mendenhall, E.M.1
Williamson, K.E.2
Reyon, D.3
Zou, J.Y.4
Ram, O.5
Joung, J.K.6
-
93
-
-
84918539650
-
Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells
-
Therizols P., Illingworth R.S., Courilleau C., Boyle S., Wood A.J., Bickmore W.A. Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells. Science 2014, 346:1238-1242.
-
(2014)
Science
, vol.346
, pp. 1238-1242
-
-
Therizols, P.1
Illingworth, R.S.2
Courilleau, C.3
Boyle, S.4
Wood, A.J.5
Bickmore, W.A.6
-
94
-
-
84930091577
-
Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions
-
Lupianez D.G., Kraft K., Heinrich V., Krawitz P., Brancati F., Klopocki E., et al. Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions. Cell 2015, 161:1012-1025.
-
(2015)
Cell
, vol.161
, pp. 1012-1025
-
-
Lupianez, D.G.1
Kraft, K.2
Heinrich, V.3
Krawitz, P.4
Brancati, F.5
Klopocki, E.6
-
95
-
-
84949100864
-
Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
-
Thakore P.I., D'Ippolito A.M., Song L., Safi A., Shivakumar N.K., Kabadi A.M., et al. Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements. Nat Methods 2015, 12:1143-1149.
-
(2015)
Nat Methods
, vol.12
, pp. 1143-1149
-
-
Thakore, P.I.1
D'Ippolito, A.M.2
Song, L.3
Safi, A.4
Shivakumar, N.K.5
Kabadi, A.M.6
-
96
-
-
84939246295
-
CRISPR Inversion of CTCF sites alters genome topology and enhancer/promoter function
-
Guo Y., Xu Q., Canzio D., Shou J., Li J., Gorkin D.U., et al. CRISPR Inversion of CTCF sites alters genome topology and enhancer/promoter function. Cell 2015, 162:900-910.
-
(2015)
Cell
, vol.162
, pp. 900-910
-
-
Guo, Y.1
Xu, Q.2
Canzio, D.3
Shou, J.4
Li, J.5
Gorkin, D.U.6
-
97
-
-
84929135130
-
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
-
Hilton I.B., D'Ippolito A.M., Vockley C.M., Thakore P.I., Crawford G.E., Reddy T.E., et al. Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. Nat Biotechnol 2015, 33:510-517.
-
(2015)
Nat Biotechnol
, vol.33
, pp. 510-517
-
-
Hilton, I.B.1
D'Ippolito, A.M.2
Vockley, C.M.3
Thakore, P.I.4
Crawford, G.E.5
Reddy, T.E.6
-
98
-
-
84948403758
-
Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes
-
Sanborn A.L., Rao S.S., Huang S.C., Durand N.C., Huntley M.H., Jewett A.I., et al. Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes. Proc Natl Acad Sci U S A 2015, 112:E6456-E6465.
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. E6456-E6465
-
-
Sanborn, A.L.1
Rao, S.S.2
Huang, S.C.3
Durand, N.C.4
Huntley, M.H.5
Jewett, A.I.6
-
99
-
-
84890206727
-
Manipulating nuclear architecture
-
Deng W., Blobel G.A. Manipulating nuclear architecture. Curr Opin Genet Dev 2014, 25:1-7.
-
(2014)
Curr Opin Genet Dev
, vol.25
, pp. 1-7
-
-
Deng, W.1
Blobel, G.A.2
-
100
-
-
84943200502
-
The 4D nucleome: evidence for a dynamic nuclear landscape based on co-aligned active and inactive nuclear compartments
-
Cremer T., Cremer M., Hubner B., Strickfaden H., Smeets D., Popken J., et al. The 4D nucleome: evidence for a dynamic nuclear landscape based on co-aligned active and inactive nuclear compartments. FEBS Lett 2015, 589:2931-2943.
-
(2015)
FEBS Lett
, vol.589
, pp. 2931-2943
-
-
Cremer, T.1
Cremer, M.2
Hubner, B.3
Strickfaden, H.4
Smeets, D.5
Popken, J.6
-
101
-
-
0035253606
-
The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells
-
Boyle S., Gilchrist S., Bridger J.M., Mahy N.L., Ellis J.A., Bickmore W.A. The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells. Hum Mol Genet 2001, 10:211-219.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 211-219
-
-
Boyle, S.1
Gilchrist, S.2
Bridger, J.M.3
Mahy, N.L.4
Ellis, J.A.5
Bickmore, W.A.6
-
102
-
-
0033553877
-
Differences in the localization and morphology of chromosomes in the human nucleus
-
Croft J.A., Bridger J.M., Boyle S., Perry P., Teague P., Bickmore W.A. Differences in the localization and morphology of chromosomes in the human nucleus. J Cell Biol 1999, 145:1119-1131.
-
(1999)
J Cell Biol
, vol.145
, pp. 1119-1131
-
-
Croft, J.A.1
Bridger, J.M.2
Boyle, S.3
Perry, P.4
Teague, P.5
Bickmore, W.A.6
-
103
-
-
46749122714
-
Replication-timing-correlated spatial chromatin arrangements in cancer and in primate interphase nuclei
-
Grasser F., Neusser M., Fiegler H., Thormeyer T., Cremer M., Carter N.P., et al. Replication-timing-correlated spatial chromatin arrangements in cancer and in primate interphase nuclei. J Cell Sci 2008, 121:1876-1886.
-
(2008)
J Cell Sci
, vol.121
, pp. 1876-1886
-
-
Grasser, F.1
Neusser, M.2
Fiegler, H.3
Thormeyer, T.4
Cremer, M.5
Carter, N.P.6
-
104
-
-
2942679507
-
Form follows function: the genomic organization of cellular differentiation
-
Kosak S.T., Groudine M. Form follows function: the genomic organization of cellular differentiation. Genes Dev 2004, 18:1371-1384.
-
(2004)
Genes Dev
, vol.18
, pp. 1371-1384
-
-
Kosak, S.T.1
Groudine, M.2
-
106
-
-
78649730557
-
Distance between homologous chromosomes results from chromosome positioning constraints
-
Heride C., Ricoul M., Kieu K., Hase von J., Guillemot V., Cremer C., et al. Distance between homologous chromosomes results from chromosome positioning constraints. J Cell Sci 2010, 123:4063-4075.
-
(2010)
J Cell Sci
, vol.123
, pp. 4063-4075
-
-
Heride, C.1
Ricoul, M.2
Kieu, K.3
Hase von, J.4
Guillemot, V.5
Cremer, C.6
-
107
-
-
0345039879
-
Global chromosome positions are transmitted through mitosis in mammalian cells
-
Gerlich D., Beaudouin J., Kalbfuss B., Daigle N., Eils R., Ellenberg J. Global chromosome positions are transmitted through mitosis in mammalian cells. Cell 2003, 112:751-764.
-
(2003)
Cell
, vol.112
, pp. 751-764
-
-
Gerlich, D.1
Beaudouin, J.2
Kalbfuss, B.3
Daigle, N.4
Eils, R.5
Ellenberg, J.6
-
108
-
-
0037416135
-
Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages
-
Walter J., Schermelleh L., Cremer M., Tashiro S., Cremer T. Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages. J Cell Biol 2003, 160:685-697.
-
(2003)
J Cell Biol
, vol.160
, pp. 685-697
-
-
Walter, J.1
Schermelleh, L.2
Cremer, M.3
Tashiro, S.4
Cremer, T.5
-
109
-
-
1142281997
-
The radial positioning of chromatin is not inherited through mitosis but is established de novo in early G1
-
Thomson I., Gilchrist S., Bickmore W.A., Chubb J.R. The radial positioning of chromatin is not inherited through mitosis but is established de novo in early G1. Curr Biol 2004, 14:166-172.
-
(2004)
Curr Biol
, vol.14
, pp. 166-172
-
-
Thomson, I.1
Gilchrist, S.2
Bickmore, W.A.3
Chubb, J.R.4
-
111
-
-
0037007044
-
Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates
-
Tanabe H., Muller S., Neusser M., Hase von J., Calcagno E., Cremer M., et al. Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates. Proc Natl Acad Sci U S A 2002, 99:4424-4429.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 4424-4429
-
-
Tanabe, H.1
Muller, S.2
Neusser, M.3
Hase von, J.4
Calcagno, E.5
Cremer, M.6
-
112
-
-
80052402894
-
Transcription factories and nuclear organization of the genome
-
Eskiw C.H., Cope N.F., Clay I., Schoenfelder S., Nagano T., Fraser P. Transcription factories and nuclear organization of the genome. Cold Spring Harb Symp Quant Biol 2010, 75:501-506.
-
(2010)
Cold Spring Harb Symp Quant Biol
, vol.75
, pp. 501-506
-
-
Eskiw, C.H.1
Cope, N.F.2
Clay, I.3
Schoenfelder, S.4
Nagano, T.5
Fraser, P.6
-
113
-
-
77952994784
-
Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types
-
Ryba T., Hiratani I., Lu J., Itoh M., Kulik M., Zhang J., et al. Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types. Genome Res 2010, 20:761-770.
-
(2010)
Genome Res
, vol.20
, pp. 761-770
-
-
Ryba, T.1
Hiratani, I.2
Lu, J.3
Itoh, M.4
Kulik, M.5
Zhang, J.6
-
114
-
-
84940090291
-
Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data
-
Fortin J.P., Hansen K.D. Reconstructing A/B compartments as revealed by Hi-C using long-range correlations in epigenetic data. Genome Biol 2015, 16:180.
-
(2015)
Genome Biol
, vol.16
, pp. 180
-
-
Fortin, J.P.1
Hansen, K.D.2
-
115
-
-
84925636391
-
Chromatin-driven behavior of topologically associating domains
-
Ciabrelli F., Cavalli G. Chromatin-driven behavior of topologically associating domains. J Mol Biol 2015, 427:608-625.
-
(2015)
J Mol Biol
, vol.427
, pp. 608-625
-
-
Ciabrelli, F.1
Cavalli, G.2
-
116
-
-
84943358862
-
Structural and functional diversity of Topologically Associating Domains
-
Dekker J., Heard E. Structural and functional diversity of Topologically Associating Domains. FEBS Lett 2015, 589:2877-2884.
-
(2015)
FEBS Lett
, vol.589
, pp. 2877-2884
-
-
Dekker, J.1
Heard, E.2
-
117
-
-
84861100147
-
Spatial partitioning of the regulatory landscape of the X-inactivation centre
-
Nora E.P., Lajoie B.R., Schulz E.G., Giorgetti L., Okamoto I., Servant N., et al. Spatial partitioning of the regulatory landscape of the X-inactivation centre. Nature 2012, 485:381-385.
-
(2012)
Nature
, vol.485
, pp. 381-385
-
-
Nora, E.P.1
Lajoie, B.R.2
Schulz, E.G.3
Giorgetti, L.4
Okamoto, I.5
Servant, N.6
-
118
-
-
84956674594
-
Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains
-
Ulianov S.V., Khrameeva E.E., Gavrilov A.A., Flyamer I.M., Kos P., Mikhaleva E.A., et al. Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains. Genome Res 2015, 26:70-84.
-
(2015)
Genome Res
, vol.26
, pp. 70-84
-
-
Ulianov, S.V.1
Khrameeva, E.E.2
Gavrilov, A.A.3
Flyamer, I.M.4
Kos, P.5
Mikhaleva, E.A.6
-
119
-
-
0016764484
-
Supercoils in human DNA
-
Cook P.R., Brazell I.A. Supercoils in human DNA. J Cell Sci 1975, 19:261-279.
-
(1975)
J Cell Sci
, vol.19
, pp. 261-279
-
-
Cook, P.R.1
Brazell, I.A.2
-
120
-
-
84946208311
-
Stable chromosome condensation revealed by chromosome conformation capture
-
Eagen K.P., Hartl T.A., Kornberg R.D. Stable chromosome condensation revealed by chromosome conformation capture. Cell 2015, 163:934-946.
-
(2015)
Cell
, vol.163
, pp. 934-946
-
-
Eagen, K.P.1
Hartl, T.A.2
Kornberg, R.D.3
-
121
-
-
84953924597
-
Insulator dysfunction and oncogene activation in IDH mutant gliomas
-
Flavahan W.A., Drier Y., Liau B.B., Gillespie S.M., Venteicher A.S., Stemmer-Rachamimov A.O., et al. Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature 2016, 529:110-114.
-
(2016)
Nature
, vol.529
, pp. 110-114
-
-
Flavahan, W.A.1
Drier, Y.2
Liau, B.B.3
Gillespie, S.M.4
Venteicher, A.S.5
Stemmer-Rachamimov, A.O.6
-
122
-
-
70450222694
-
A model for all genomes: the role of transcription factories
-
Cook P.R. A model for all genomes: the role of transcription factories. J Mol Biol 2010, 395:1-10.
-
(2010)
J Mol Biol
, vol.395
, pp. 1-10
-
-
Cook, P.R.1
-
123
-
-
80255137474
-
The proteomes of transcription factories containing RNA polymerases I, II or III
-
Melnik S., Deng B., Papantonis A., Baboo S., Carr I.M., Cook P.R. The proteomes of transcription factories containing RNA polymerases I, II or III. Nat Methods 2011, 8:963-968.
-
(2011)
Nat Methods
, vol.8
, pp. 963-968
-
-
Melnik, S.1
Deng, B.2
Papantonis, A.3
Baboo, S.4
Carr, I.M.5
Cook, P.R.6
-
124
-
-
84899873434
-
Imaging RNA Polymerase II transcription sites in living cells
-
Buckley M.S., Lis J.T. Imaging RNA Polymerase II transcription sites in living cells. Curr Opin Genet Dev 2014, 25:126-130.
-
(2014)
Curr Opin Genet Dev
, vol.25
, pp. 126-130
-
-
Buckley, M.S.1
Lis, J.T.2
-
125
-
-
84940473396
-
An overview of genome organization and how we got there: from FISH to Hi-C
-
Fraser J., Williamson I., Bickmore W.A., Dostie J. An overview of genome organization and how we got there: from FISH to Hi-C. Microbiol Mol Biol Rev 2015, 79:347-372.
-
(2015)
Microbiol Mol Biol Rev
, vol.79
, pp. 347-372
-
-
Fraser, J.1
Williamson, I.2
Bickmore, W.A.3
Dostie, J.4
-
127
-
-
78149295090
-
High-resolution whole-genome sequencing reveals that specific chromatin domains from most human chromosomes associate with nucleoli
-
van Koningsbruggen S., Gierlinski M., Schofield P., Martin D., Barton G.J., Ariyurek Y., et al. High-resolution whole-genome sequencing reveals that specific chromatin domains from most human chromosomes associate with nucleoli. Mol Biol Cell 2010, 21:3735-3748.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 3735-3748
-
-
van Koningsbruggen, S.1
Gierlinski, M.2
Schofield, P.3
Martin, D.4
Barton, G.J.5
Ariyurek, Y.6
-
128
-
-
77952576224
-
Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation
-
Peric-Hupkes D., Meuleman W., Pagie L., Bruggeman S.W., Solovei I., Brugman W., et al. Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation. Mol Cell 2010, 38:603-613.
-
(2010)
Mol Cell
, vol.38
, pp. 603-613
-
-
Peric-Hupkes, D.1
Meuleman, W.2
Pagie, L.3
Bruggeman, S.W.4
Solovei, I.5
Brugman, W.6
-
129
-
-
0022545056
-
DNA loops induced by cooperative binding of γ repressor
-
Griffith J., Hochschild A., Ptashne M. DNA loops induced by cooperative binding of γ repressor. Nature 1986, 322:750-752.
-
(1986)
Nature
, vol.322
, pp. 750-752
-
-
Griffith, J.1
Hochschild, A.2
Ptashne, M.3
-
130
-
-
84900297485
-
Predictive polymer modeling reveals coupled fluctuations in chromosome conformation and transcription
-
Giorgetti L., Galupa R., Nora E.P., Piolot T., Lam F., Dekker J., et al. Predictive polymer modeling reveals coupled fluctuations in chromosome conformation and transcription. Cell 2014, 157:950-963.
-
(2014)
Cell
, vol.157
, pp. 950-963
-
-
Giorgetti, L.1
Galupa, R.2
Nora, E.P.3
Piolot, T.4
Lam, F.5
Dekker, J.6
-
131
-
-
0036923833
-
Looping and interaction between hypersensitive sites in the active beta-globin locus
-
Tolhuis B., Palstra R.J., Splinter E., Grosveld F., de Laat W. Looping and interaction between hypersensitive sites in the active beta-globin locus. Mol Cell 2002, 10:1453-1465.
-
(2002)
Mol Cell
, vol.10
, pp. 1453-1465
-
-
Tolhuis, B.1
Palstra, R.J.2
Splinter, E.3
Grosveld, F.4
de Laat, W.5
-
132
-
-
84887620842
-
A high-resolution map of the three-dimensional chromatin interactome in human cells
-
Jin F., Li Y., Dixon J.R., Selvaraj S., Ye Z., Lee A.Y., et al. A high-resolution map of the three-dimensional chromatin interactome in human cells. Nature 2013, 503:290-294.
-
(2013)
Nature
, vol.503
, pp. 290-294
-
-
Jin, F.1
Li, Y.2
Dixon, J.R.3
Selvaraj, S.4
Ye, Z.5
Lee, A.Y.6
-
133
-
-
84862908850
-
Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation
-
Li G., Ruan X., Auerbach R.K., Sandhu K.S., Zheng M., Wang P., et al. Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation. Cell 2012, 148:84-98.
-
(2012)
Cell
, vol.148
, pp. 84-98
-
-
Li, G.1
Ruan, X.2
Auerbach, R.K.3
Sandhu, K.S.4
Zheng, M.5
Wang, P.6
-
134
-
-
84865800494
-
The long-range interaction landscape of gene promoters
-
Sanyal A., Lajoie B.R., Jain G., Dekker J. The long-range interaction landscape of gene promoters. Nature 2012, 489:109-113.
-
(2012)
Nature
, vol.489
, pp. 109-113
-
-
Sanyal, A.1
Lajoie, B.R.2
Jain, G.3
Dekker, J.4
-
135
-
-
84890432056
-
Chromatin connectivity maps reveal dynamic promoter-enhancer long-range associations
-
Zhang Y., Wong C.H., Birnbaum R.Y., Li G., Favaro R., Ngan C.Y., et al. Chromatin connectivity maps reveal dynamic promoter-enhancer long-range associations. Nature 2013, 504:306-310.
-
(2013)
Nature
, vol.504
, pp. 306-310
-
-
Zhang, Y.1
Wong, C.H.2
Birnbaum, R.Y.3
Li, G.4
Favaro, R.5
Ngan, C.Y.6
-
136
-
-
84905593782
-
Enhancer loops appear stable during development and are associated with paused polymerase
-
Ghavi-Helm Y., Klein F.A., Pakozdi T., Ciglar L., Noordermeer D., Huber W., et al. Enhancer loops appear stable during development and are associated with paused polymerase. Nature 2014, 512:96-100.
-
(2014)
Nature
, vol.512
, pp. 96-100
-
-
Ghavi-Helm, Y.1
Klein, F.A.2
Pakozdi, T.3
Ciglar, L.4
Noordermeer, D.5
Huber, W.6
-
137
-
-
84861964135
-
Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor
-
Deng W., Lee J., Wang H., Miller J., Reik A., Gregory P.D., et al. Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor. Cell 2012, 149:1233-1244.
-
(2012)
Cell
, vol.149
, pp. 1233-1244
-
-
Deng, W.1
Lee, J.2
Wang, H.3
Miller, J.4
Reik, A.5
Gregory, P.D.6
-
138
-
-
84908439526
-
Reactivation of developmentally silenced globin genes by forced chromatin looping
-
Deng W., Rupon J.W., Krivega I., Breda L., Motta I., Jahn K.S., et al. Reactivation of developmentally silenced globin genes by forced chromatin looping. Cell 2014, 158:849-860.
-
(2014)
Cell
, vol.158
, pp. 849-860
-
-
Deng, W.1
Rupon, J.W.2
Krivega, I.3
Breda, L.4
Motta, I.5
Jahn, K.S.6
-
140
-
-
84871069553
-
Epigenetic regulation by long noncoding RNAs
-
Lee J.T. Epigenetic regulation by long noncoding RNAs. Science 2012, 338:1435-1439.
-
(2012)
Science
, vol.338
, pp. 1435-1439
-
-
Lee, J.T.1
-
141
-
-
84893767092
-
Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre
-
Hacisuleyman E., Goff L.A., Trapnell C., Williams A., Henao-Mejia J., Sun L., et al. Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre. Nat Struct Mol Biol 2014, 21:198-206.
-
(2014)
Nat Struct Mol Biol
, vol.21
, pp. 198-206
-
-
Hacisuleyman, E.1
Goff, L.A.2
Trapnell, C.3
Williams, A.4
Henao-Mejia, J.5
Sun, L.6
-
142
-
-
84938412430
-
The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation
-
Yang F., Deng X., Ma W., Berletch J.B., Rabaia N., Wei G., et al. The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation. Genome Biol 2015, 16:52.
-
(2015)
Genome Biol
, vol.16
, pp. 52
-
-
Yang, F.1
Deng, X.2
Ma, W.3
Berletch, J.B.4
Rabaia, N.5
Wei, G.6
-
143
-
-
79953748673
-
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
-
Wang K.C., Yang Y.W., Liu B., Sanyal A., Corces-Zimmerman R., Chen Y., et al. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature 2011, 472:120-124.
-
(2011)
Nature
, vol.472
, pp. 120-124
-
-
Wang, K.C.1
Yang, Y.W.2
Liu, B.3
Sanyal, A.4
Corces-Zimmerman, R.5
Chen, Y.6
-
144
-
-
67549119096
-
CTCF: master weaver of the genome
-
Phillips J.E., Corces V.G. CTCF: master weaver of the genome. Cell 2009, 137:1194-1211.
-
(2009)
Cell
, vol.137
, pp. 1194-1211
-
-
Phillips, J.E.1
Corces, V.G.2
-
145
-
-
0025675441
-
A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5'-flanking sequence of the chicken c-myc gene
-
Lobanenkov V.V., Nicolas R.H., Adler V.V., Paterson H., Klenova E.M., Polotskaja A.V., et al. A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5'-flanking sequence of the chicken c-myc gene. Oncogene 1990, 5:1743-1753.
-
(1990)
Oncogene
, vol.5
, pp. 1743-1753
-
-
Lobanenkov, V.V.1
Nicolas, R.H.2
Adler, V.V.3
Paterson, H.4
Klenova, E.M.5
Polotskaja, A.V.6
-
146
-
-
0033529654
-
The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
-
Bell A.C., West A.G., Felsenfeld G. The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell 1999, 98:387-396.
-
(1999)
Cell
, vol.98
, pp. 387-396
-
-
Bell, A.C.1
West, A.G.2
Felsenfeld, G.3
-
147
-
-
77952563068
-
Condensin and cohesin complexity: the expanding repertoire of functions
-
Wood A.J., Severson A.F., Meyer B.J. Condensin and cohesin complexity: the expanding repertoire of functions. Nat Rev Genet 2010, 11:391-404.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 391-404
-
-
Wood, A.J.1
Severson, A.F.2
Meyer, B.J.3
-
148
-
-
84916880365
-
Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes
-
Dowen J.M., Fan Z.P., Hnisz D., Ren G., Abraham B.J., Zhang L.N., et al. Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes. Cell 2014, 159:374-387.
-
(2014)
Cell
, vol.159
, pp. 374-387
-
-
Dowen, J.M.1
Fan, Z.P.2
Hnisz, D.3
Ren, G.4
Abraham, B.J.5
Zhang, L.N.6
-
149
-
-
79959699992
-
CTCF-mediated functional chromatin interactome in pluripotent cells
-
Handoko L., Xu H., Li G., Ngan C.Y., Chew E., Schnapp M., et al. CTCF-mediated functional chromatin interactome in pluripotent cells. Nat Genet 2011, 43:630-638.
-
(2011)
Nat Genet
, vol.43
, pp. 630-638
-
-
Handoko, L.1
Xu, H.2
Li, G.3
Ngan, C.Y.4
Chew, E.5
Schnapp, M.6
-
150
-
-
84957850407
-
3D chromosome regulatory landscape of human pluripotent cells
-
Ji X., Dadon D.B., Powell B.E., Fan Z.P., Borges-Rivera D., Shachar S., et al. 3D chromosome regulatory landscape of human pluripotent cells. Cell Stem Cell 2015.
-
(2015)
Cell Stem Cell
-
-
Ji, X.1
Dadon, D.B.2
Powell, B.E.3
Fan, Z.P.4
Borges-Rivera, D.5
Shachar, S.6
-
151
-
-
77957139539
-
Mediator and cohesin connect gene expression and chromatin architecture
-
Kagey M.H., Newman J.J., Bilodeau S., Zhan Y., Orlando D.A., van Berkum N.L., et al. Mediator and cohesin connect gene expression and chromatin architecture. Nature 2010, 467:430-435.
-
(2010)
Nature
, vol.467
, pp. 430-435
-
-
Kagey, M.H.1
Newman, J.J.2
Bilodeau, S.3
Zhan, Y.4
Orlando, D.A.5
van Berkum, N.L.6
-
152
-
-
84947765898
-
CTCF binding polarity determines chromatin looping
-
de Wit E., Vos E.S., Holwerda S.J., Valdes-Quezada C., Verstegen M.J., Teunissen H., et al. CTCF binding polarity determines chromatin looping. Mol Cell 2015, 60:676-684.
-
(2015)
Mol Cell
, vol.60
, pp. 676-684
-
-
de Wit, E.1
Vos, E.S.2
Holwerda, S.J.3
Valdes-Quezada, C.4
Verstegen, M.J.5
Teunissen, H.6
-
153
-
-
84871208196
-
Self-organization of domain structures by DNA-loop-extruding enzymes
-
Alipour E., Marko J.F. Self-organization of domain structures by DNA-loop-extruding enzymes. Nucleic Acids Res 2012, 40:11202-11212.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 11202-11212
-
-
Alipour, E.1
Marko, J.F.2
-
154
-
-
84892934183
-
Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells
-
Zuin J., Dixon J.R., van der Reijden M.I.J.A., Ye Z., Kolovos P., Brouwer R.W.W., et al. Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells. Proc Natl Acad Sci U S A 2014, 111:996-1001.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 996-1001
-
-
Zuin, J.1
Dixon, J.R.2
van der Reijden, M.I.J.A.3
Ye, Z.4
Kolovos, P.5
Brouwer, R.W.W.6
-
155
-
-
84892765883
-
Genome-scale CRISPR-Cas9 knockout screening in human cells
-
Shalem O., Sanjana N.E., Hartenian E., Shi X., Scott D.A., Mikkelsen T.S., et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 2014, 343:84-87.
-
(2014)
Science
, vol.343
, pp. 84-87
-
-
Shalem, O.1
Sanjana, N.E.2
Hartenian, E.3
Shi, X.4
Scott, D.A.5
Mikkelsen, T.S.6
-
156
-
-
84892749369
-
Genetic screens in human cells using the CRISPR-Cas9 system
-
Wang T., Wei J.J., Sabatini D.M., Lander E.S. Genetic screens in human cells using the CRISPR-Cas9 system. Science 2014, 343:80-84.
-
(2014)
Science
, vol.343
, pp. 80-84
-
-
Wang, T.1
Wei, J.J.2
Sabatini, D.M.3
Lander, E.S.4
-
157
-
-
84947471999
-
Identification and characterization of essential genes in the human genome
-
Wang T., Birsoy K., Hughes N.W., Krupczak K.M., Post Y., Wei J.J., et al. Identification and characterization of essential genes in the human genome. Science 2015, 350:1096-1101.
-
(2015)
Science
, vol.350
, pp. 1096-1101
-
-
Wang, T.1
Birsoy, K.2
Hughes, N.W.3
Krupczak, K.M.4
Post, Y.5
Wei, J.J.6
-
158
-
-
84907257107
-
Saturation editing of genomic regions by multiplex homology-directed repair
-
Findlay G.M., Boyle E.A., Hause R.J., Klein J.C., Shendure J. Saturation editing of genomic regions by multiplex homology-directed repair. Nature 2014, 513:120-123.
-
(2014)
Nature
, vol.513
, pp. 120-123
-
-
Findlay, G.M.1
Boyle, E.A.2
Hause, R.J.3
Klein, J.C.4
Shendure, J.5
-
159
-
-
84959104222
-
Functional footprinting of regulatory DNA
-
Vierstra J., Reik A., Chang K.-H., Stehling-Sun S., Zhou Y., Hinkley S.J., et al. Functional footprinting of regulatory DNA. Nat Methods 2015, 12:927-930.
-
(2015)
Nat Methods
, vol.12
, pp. 927-930
-
-
Vierstra, J.1
Reik, A.2
Chang, K.-H.3
Stehling-Sun, S.4
Zhou, Y.5
Hinkley, S.J.6
-
160
-
-
84946925193
-
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis
-
Canver M.C., Smith E.C., Sher F., Pinello L., Sanjana N.E., Shalem O., et al. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature 2015, 527:192-197.
-
(2015)
Nature
, vol.527
, pp. 192-197
-
-
Canver, M.C.1
Smith, E.C.2
Sher, F.3
Pinello, L.4
Sanjana, N.E.5
Shalem, O.6
-
161
-
-
84947617259
-
Single-cell epigenomics: techniques and emerging applications
-
Schwartzman O., Tanay A. Single-cell epigenomics: techniques and emerging applications. Nat Rev Genet 2015, 16:716-726.
-
(2015)
Nat Rev Genet
, vol.16
, pp. 716-726
-
-
Schwartzman, O.1
Tanay, A.2
-
162
-
-
84930006926
-
Epigenetics. Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing
-
Cusanovich D.A., Daza R., Adey A., Pliner H.A., Christiansen L., Gunderson K.L., et al. Epigenetics. Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing. Science 2015, 348:910-914.
-
(2015)
Science
, vol.348
, pp. 910-914
-
-
Cusanovich, D.A.1
Daza, R.2
Adey, A.3
Pliner, H.A.4
Christiansen, L.5
Gunderson, K.L.6
-
163
-
-
84863202666
-
Single-cell systems biology by super-resolution imaging and combinatorial labeling
-
Lubeck E., Cai L. Single-cell systems biology by super-resolution imaging and combinatorial labeling. Nat Methods 2012, 9:743-748.
-
(2012)
Nat Methods
, vol.9
, pp. 743-748
-
-
Lubeck, E.1
Cai, L.2
-
164
-
-
84897452794
-
Single-cell in situ RNA profiling by sequential hybridization
-
Lubeck E., Coskun A.F., Zhiyentayev T., Ahmad M., Cai L. Single-cell in situ RNA profiling by sequential hybridization. Nat Methods 2014, 11:360-361.
-
(2014)
Nat Methods
, vol.11
, pp. 360-361
-
-
Lubeck, E.1
Coskun, A.F.2
Zhiyentayev, T.3
Ahmad, M.4
Cai, L.5
-
165
-
-
84897090228
-
Highly multiplexed subcellular RNA sequencing in situ
-
Lee J.H., Daugharthy E.R., Scheiman J., Kalhor R., Yang J.L., Ferrante T.C., et al. Highly multiplexed subcellular RNA sequencing in situ. Science 2014, 343:1360-1363.
-
(2014)
Science
, vol.343
, pp. 1360-1363
-
-
Lee, J.H.1
Daugharthy, E.R.2
Scheiman, J.3
Kalhor, R.4
Yang, J.L.5
Ferrante, T.C.6
-
166
-
-
84928395184
-
RNA imaging. Spatially resolved, highly multiplexed RNA profiling in single cells
-
aaa6090-0
-
Chen K.H., Boettiger A.N., Moffitt J.R., Wang S., Zhuang X. RNA imaging. Spatially resolved, highly multiplexed RNA profiling in single cells. Science 2015, 348. aaa6090-0.
-
(2015)
Science
, vol.348
-
-
Chen, K.H.1
Boettiger, A.N.2
Moffitt, J.R.3
Wang, S.4
Zhuang, X.5
-
167
-
-
84942940566
-
Defining cell types and states with single-cell genomics
-
Trapnell C. Defining cell types and states with single-cell genomics. Genome Res 2015, 25:1491-1498.
-
(2015)
Genome Res
, vol.25
, pp. 1491-1498
-
-
Trapnell, C.1
|