The Radial Positioning of Chromatin Is Not Inherited through Mitosis but Is Established de Novo in Early G1

Current Biology

Volumn 14, Issue 2, 2004, Pages 166-172

  Thomson, Inga ^a   Gilchrist, Susan ^a   Bickmore, Wendy A ^a   Chubb, Jonathan R ^a,b  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 1142281997     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2003.12.024     Document Type: Article

References (16)

1. Csink A.K., Henikoff S. Genetic modification of heterochromatic association and nuclear organization in Drosophila. Nature. 381:1996;529-531.
2. Brown K.E., Guest S.S., Smale S.T., Hahm K., Merkenschlager M., Fisher A.G. Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin. Cell. 91:1997;845-854.
3. Andrulis E.D., Neiman A.M., Zappulla D.C., Sternglanz R. Perinuclear localization of chromatin facilitates transcriptional silencing. Nature. 394:1998;592-595.
4. Walter J., Schermelleh L., Cremer M., Tashiro S., Cremer T. Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages. J. Cell Biol. 160:2003;685-697.
5. Gerlich D., Beaudouin J., Kalbfuss B., Daigle N., Eils R., Ellenberg J. Global chromosome positions are transmitted through mitosis in mammalian cells. Cell. 112:2003;751-764.
6. Bickmore W.A., Chubb J.R. Chromosome position. Now where was I? Curr. Biol. 13:2003;R357-R359.
7. Williams R.R., Fisher A.G. Chromosomes, positions please! Nat. Cell Biol. 5:2003;388-390.
8. Parada L.A., Roix J.L., Misteli T. An uncertainty principle in chromosome positioning. Trends Cell Biol. 13:2003;393-396.
9. Chubb J.R., Boyle S., Perry P., Bickmore W.A. Chromatin motion is constrained by association with nuclear compartments in human cells. Curr. Biol. 12:2002;439-445.
10. Marshall W.F., Straight A., Marko J.F., Swedlow J., Dernburg A., Belmont A., Murray A.W., Agard D.A., Sedat J.W. Interphase chromosomes undergo constrained diffusional motion in living cells. Curr. Biol. 7:1997;930-939.
11. Vazquez J., Belmont A., Sedat J.W. Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus. Curr. Biol. 11:2001;1227-1239.
12. Shelby R.D., Hahn K.M., Sullivan K.F. Dynamic elastic behavior of alpha-satellite DNA domains visualized in situ in living human cells. J. Cell Biol. 135:1996;545-557.
13. Dimitrova D.S., Gilbert D.M. The spatial position and timing of chromosomal domains are both established in early G1 phase. Mol. Cell. 4:1999;983-993.
14. Bridger J.M., Boyle S., Kill I.R., Bickmore W.A. Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts. Curr. Biol. 10:2000;149-152.
15. Li G., Sudlow G., Belmont A.S. Interphase cell cycle dynamics of a late-replicating, heterochromatic homogenously staining region. precise choreography of condensation/decondensation and nuclear positioning J. Cell Biol. 140:1998;975-989.
16. Tumbar T., Belmont A.S. Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator. Nat. Cell Biol. 2:2001;134-139.