메뉴 건너뛰기




Volumn 816, Issue , 2014, Pages 259-313

The role of inflammation in sarcoma

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; BRIVANIB; CAPECITABINE; CEDIRANIB; CIXUTUMUMAB; DACARBAZINE; DASATINIB; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; ERIBULIN; EVEROLIMUS; GEMCITABINE; IFOSFAMIDE; IMATINIB; IXABEPILONE; MESNA; MOTESANIB; NILOTINIB; PACLITAXEL; PAZOPANIB; RAPAMYCIN; RETASPIMYCIN; RIDAFOROLIMUS; SORAFENIB; SUNITINIB; TEMSIROLIMUS; TIVANTINIB; TRABECTEDIN; UNINDEXED DRUG; ANGIOGENIN; CELECOXIB; MICRORNA; MICRORNA 155; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOPONTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN H2 SYNTHASE 2; PROSTAGLANDIN SYNTHASE; PROTEIN FOXM1; PROTEIN KINASE B; PROTEIN KINASE LYN; RAF PROTEIN; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; SOMATOMEDIN C RECEPTOR; SONIC HEDGEHOG PROTEIN; THALIDOMIDE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 84959190662     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-348-837-8_11     Document Type: Article
Times cited : (18)

References (393)
  • 1
    • 0025944684 scopus 로고
    • Activation of the NADPH oxidase involves the small GTPbinding protein p21rac1
    • Abo A, Pick E, Hall A et al (1991) Activation of the NADPH oxidase involves the small GTPbinding protein p21rac1. Nature 353:668-670
    • (1991) Nature , vol.353 , pp. 668-670
    • Abo, A.1    Pick, E.2    Hall, A.3
  • 2
    • 79959349882 scopus 로고    scopus 로고
    • Pr eclinical testing of erlotinib in a transgenic alveolar rhabdomyosarcoma mouse model
    • doi:10.1155/2011/130484
    • Abraham J, Nelon LD, Kubicek CB et al (2011) Pr eclinical testing of erlotinib in a transgenic alveolar rhabdomyosarcoma mouse model. Sarcoma 2011:130484. doi:10.1155/2011/130484
    • (2011) Sarcoma , vol.2011 , pp. 130484
    • Abraham, J.1    Nelon, L.D.2    Kubicek, C.B.3
  • 3
    • 68849108869 scopus 로고    scopus 로고
    • Inflammation and cancer: How friendly is the relationship for cancer patients?
    • Aggarwal BB, Gehlot P (2009) Inflammation and cancer: how friendly is the relationship for cancer patients? Curr Opin Pharmacol 9:351-369
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 351-369
    • Aggarwal, B.B.1    Gehlot, P.2
  • 4
    • 84055206678 scopus 로고    scopus 로고
    • New developments in mammalian target of rapamycin inhibitors for the treatment of sarcoma
    • Agulnik M (2012) New developments in mammalian target of rapamycin inhibitors for the treatment of sarcoma. Cancer 118:1486-1497
    • (2012) Cancer , vol.118 , pp. 1486-1497
    • Agulnik, M.1
  • 5
    • 84876506864 scopus 로고    scopus 로고
    • An open-label, multicenter, phase II study of bevacizumab for the treatment of angiosarcoma and epithelioid hemangioendotheliomas
    • Agulnik M, Yarber JL, Okuno SH et al (2013) An open-label, multicenter, phase II study of bevacizumab for the treatment of angiosarcoma and epithelioid hemangioendotheliomas. Ann Oncol 24:257-263
    • (2013) Ann Oncol , vol.24 , pp. 257-263
    • Agulnik, M.1    Yarber, J.L.2    Okuno, S.H.3
  • 6
    • 0033799097 scopus 로고    scopus 로고
    • Acquired and congenital cholesteatoma: Determination of tumor necrosis factor-alpha, intercellular adhesion molecule-1, interleukin-1-alpha and lymphocyte functional antigen-1 in the inflammatory process
    • Akimoto R, Pawankar R, Yagi T et al (2000) Acquired and congenital cholesteatoma: determination of tumor necrosis factor-alpha, intercellular adhesion molecule-1, interleukin-1-alpha and lymphocyte functional antigen-1 in the inflammatory process. ORL J Otorhinolaryngol Relat Spec 62:257-265
    • (2000) ORL J Otorhinolaryngol Relat Spec , vol.62 , pp. 257-265
    • Akimoto, R.1    Pawankar, R.2    Yagi, T.3
  • 7
    • 0033144001 scopus 로고    scopus 로고
    • Analysis of cyclin dependent kinase inhibitors in malignant astrocytomas
    • Alleyne CH Jr, He J, Yang J et al (1999) Analysis of cyclin dependent kinase inhibitors in malignant astrocytomas. Int J Oncol 14:1111-1116
    • (1999) Int J Oncol , vol.14 , pp. 1111-1116
    • Alleyne Jr., C.H.1    He, J.2    Yang, J.3
  • 8
    • 34447506658 scopus 로고    scopus 로고
    • Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis
    • Ancrile B, Lim KH, Counter CM (2007) Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis. Genes Dev 21:1714-1719
    • (2007) Genes Dev , vol.21 , pp. 1714-1719
    • Ancrile, B.1    Lim, K.H.2    Counter, C.M.3
  • 9
    • 78649990580 scopus 로고    scopus 로고
    • Osteopontin is up-regulated and associated with neutrophil and macrophage infiltration in glioblastoma
    • Atai NA Bansal M Lo C et al 2011 Osteopontin is up-regulated and associated with neutrophil and macrophage infiltration in glioblastoma Immunology 132: 39-48
    • (2011) Immunology , vol.132 , pp. 39-48
    • Atai, N.A.1    Bansal, M.2    Lo, C.3
  • 10
    • 34547946896 scopus 로고    scopus 로고
    • Antihyperalg esic effects induced by the IL-1 receptor antagonist anakinra and increased IL-1beta levels in inflamed and osteosarcomabearing mice
    • Baamonde A, Curto-Reyes V, Juarez L et al (2007) Antihyperalg esic effects induced by the IL-1 receptor antagonist anakinra and increased IL-1beta levels in inflamed and osteosarcomabearing mice. Life Sci 81:673-682
    • (2007) Life Sci , vol.81 , pp. 673-682
    • Baamonde, A.1    Curto-Reyes, V.2    Juarez, L.3
  • 11
    • 77952307612 scopus 로고    scopus 로고
    • Elevated tumor and serum levels of the hypoxiaassociated protein osteopontin are associated with prognosis for soft tissue sarcoma patients
    • doi:10.1186/1471-2407-10-132
    • Bache M, Kappler M, Wichmann H et al (2010) Elevated tumor and serum levels of the hypoxiaassociated protein osteopontin are associated with prognosis for soft tissue sarcoma patients. BMC Cancer 10:132. doi:10.1186/1471-2407-10-132
    • (2010) BMC Cancer , vol.10 , pp. 132
    • Bache, M.1    Kappler, M.2    Wichmann, H.3
  • 12
    • 84861158485 scopus 로고    scopus 로고
    • Phosphoproteomics identifies driver tyrosine kinases in sarcoma cell lines and tumors
    • Bai Y, Li J, Fang B et al (2012) Phosphoproteomics identifies driver tyrosine kinases in sarcoma cell lines and tumors. Cancer Res 72:2501-2511
    • (2012) Cancer Res , vol.72 , pp. 2501-2511
    • Bai, Y.1    Li, J.2    Fang, B.3
  • 13
    • 70449091786 scopus 로고    scopus 로고
    • Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
    • Barbie DA, Tamayo P, Boehm JS et al (2009) Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature 462:108-112
    • (2009) Nature , vol.462 , pp. 108-112
    • Barbie, D.A.1    Tamayo, P.2    Boehm, J.S.3
  • 14
    • 0030966101 scopus 로고    scopus 로고
    • The role of Ets transcription factors in the development and function of the mammalian immune system
    • Bassuk AG, Leiden JM (1997) The role of Ets transcription factors in the development and function of the mammalian immune system. Adv Immunol 64:65-104
    • (1997) Adv Immunol , vol.64 , pp. 65-104
    • Bassuk, A.G.1    Leiden, J.M.2
  • 15
    • 33745444832 scopus 로고    scopus 로고
    • Docetaxel and gemcitabine combination in 133 advanced soft-tissue sarcomas: A retrospective analysis
    • Bay JO, Ray-Coquard I, Fayette J et al (2006) Docetaxel and gemcitabine combination in 133 advanced soft-tissue sarcomas: a retrospective analysis. Int J Cancer 119:706-711
    • (2006) Int J Cancer , vol.119 , pp. 706-711
    • Bay, J.O.1    Ray-Coquard, I.2    Fayette, J.3
  • 16
    • 0035136839 scopus 로고    scopus 로고
    • Metalloproteinase expression and prognosis in soft tissue sarcomas
    • Benassi MS, Gamberi G, Magagnoli G et al (2001) Metalloproteinase expression and prognosis in soft tissue sarcomas. Ann Oncol 12:75-80
    • (2001) Ann Oncol , vol.12 , pp. 75-80
    • Benassi, M.S.1    Gamberi, G.2    Magagnoli, G.3
  • 17
    • 84871207566 scopus 로고    scopus 로고
    • Clinical activity of mTOR inhibition in combination with cyclophosphamide in the treatment of recurrent unresectable chondrosarcomas
    • Bernstein-Molho R, Kollender Y, Issakov J et al (2012) Clinical activity of mTOR inhibition in combination with cyclophosphamide in the treatment of recurrent unresectable chondrosarcomas. Cancer Chemother Pharmacol 70:855-860
    • (2012) Cancer Chemother Pharmacol , vol.70 , pp. 855-860
    • Bernstein-Molho, R.1    Kollender, Y.2    Issakov, J.3
  • 19
    • 8844278362 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
    • Bond GL, Hu W, Bond EE et al (2004) A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans. Cell 119:591-602
    • (2004) Cell , vol.119 , pp. 591-602
    • Bond, G.L.1    Hu, W.2    Bond, E.E.3
  • 20
    • 35348928702 scopus 로고    scopus 로고
    • The effect of monohydroxyethylrutoside on doxorubicin-induced cardiotoxicity in patients treated for metastatic cancer in a phase II study
    • Bruynzeel AM, Niessen HW, Bronzwaer JG et al (2007) The effect of monohydroxyethylrutoside on doxorubicin-induced cardiotoxicity in patients treated for metastatic cancer in a phase II study. Br J Cancer 97:10 84-1089
    • (2007) Br J Cancer , vol.97 , pp. 1084-1089
    • Bruynzeel, A.M.1    Niessen, H.W.2    Bronzwaer, J.G.3
  • 21
    • 84872307434 scopus 로고    scopus 로고
    • The epidemiology of sarcoma
    • doi:10.1186/2045-3329-2-14
    • Burningham Z, Hashibe M, Spector L et al (2012) The epidemiology of sarcoma. Clin Sarcoma Res 2:14. doi:10.1186/2045-3329-2-14
    • (2012) Clin Sarcoma Res , vol.2 , pp. 14
    • Burningham, Z.1    Hashibe, M.2    Spector, L.3
  • 22
    • 78049428879 scopus 로고    scopus 로고
    • Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor
    • Butrynski JE, D'Adamo DR, Hornick JL et al (2010) Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor. N Engl J Med 363:1727-1733
    • (2010) N Engl J Med , vol.363 , pp. 1727-1733
    • Butrynski, J.E.1    D'Adamo, D.R.2    Hornick, J.L.3
  • 23
    • 77957782177 scopus 로고    scopus 로고
    • Down-regulation of Wee1 kinase by a specific subset of microRNA in human sporadic pituitary adenomas
    • Butz H, Liko I, Czirjak S et al (2010) Down-regulation of Wee1 kinase by a specific subset of microRNA in human sporadic pituitary adenomas. J Clin Endocrinol Metab 95:E181-E191
    • (2010) J Clin Endocrinol Metab , vol.95
    • Butz, H.1    Liko, I.2    Czirjak, S.3
  • 24
    • 84859706280 scopus 로고    scopus 로고
    • At-risk populations for osteosarcoma: The syndromes and beyond
    • doi:10.1155/2012/152382
    • Calvert GT, Randall RL, Jones KB et al (2012) At-risk populations for osteosarcoma: the syndromes and beyond. Sarcoma 2012:152382. doi:10.1155/2012/152382
    • (2012) Sarcoma , vol.2012 , pp. 152382
    • Calvert, G.T.1    Randall, R.L.2    Jones, K.B.3
  • 25
    • 80053518938 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is not associated with clinical outcome in synovial sarcoma
    • Carmody Soni EE, Miller BJ, Scarborough MT et al (2011) Cyclooxygenase-2 expression is not associated with clinical outcome in synovial sarcoma. Oncol Rep 26:1513-1517
    • (2011) Oncol Rep , vol.26 , pp. 1513-1517
    • Carmody Soni, E.E.1    Miller, B.J.2    Scarborough, M.T.3
  • 26
    • 33646358695 scopus 로고    scopus 로고
    • The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans
    • Carrasco DR, Fenton T, Sukhdeo K et al (2006) The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans. Cancer C ell 9:379-390
    • (2006) Cancer C Ell , vol.9 , pp. 379-390
    • Carrasco, D.R.1    Fenton, T.2    Sukhdeo, K.3
  • 27
    • 78649993667 scopus 로고    scopus 로고
    • Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma
    • Castilla MA, Moreno-Bueno G, Romero-Perez L et al (2011) Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma. J Pathol 223:72-80
    • (2011) J Pathol , vol.223 , pp. 72-80
    • Castilla, M.A.1    Moreno-Bueno, G.2    Romero-Perez, L.3
  • 28
    • 84861820085 scopus 로고    scopus 로고
    • Inhibition of nuclear factor-kappaB by dehydroxymethylepoxyquinomicin induces schedule-dependent chemosensitivity to anticancer drugs and enhances chemoinduced apoptosis in osteosarcoma cells
    • Castro-Gamero AM, Borges KS, da Silva Silveira V et al (2012) Inhibition of nuclear factor-kappaB by dehydroxymethylepoxyquinomicin induces schedule-dependent chemosensitivity to anticancer drugs and enhances chemoinduced apoptosis in osteosarcoma cells. Anticancer Drugs 23:638-650
    • (2012) Anticancer Drugs , vol.23 , pp. 638-650
    • Castro-Gamero, A.M.1    Borges, K.S.2    Da Silva Silveira, V.3
  • 29
    • 34548598298 scopus 로고    scopus 로고
    • PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound
    • Cen L, Hsieh FC, Lin HJ et al (2007) PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound. Br J Cancer 97:785-791
    • (2007) Br J Cancer , vol.97 , pp. 785-791
    • Cen, L.1    Hsieh, F.C.2    Lin, H.J.3
  • 30
    • 34249709906 scopus 로고    scopus 로고
    • Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process
    • doi:10.1186/1471-2407-7-64
    • Chandran UR, Ma C, Dhir R et al (2007) Gene expression profiles of prostate cancer reveal involvement of multiple molecular pathways in the metastatic process. BMC Cancer 7:64. doi:10.1186/1471-2407-7-64
    • (2007) BMC Cancer , vol.7 , pp. 64
    • Chandran, U.R.1    Ma, C.2    Dhir, R.3
  • 31
    • 0242475362 scopus 로고    scopus 로고
    • Osteopontin induction is required for tumor promoter-induced transformation of preneoplastic mouse cells
    • Chang PL, Cao M, Hicks P (2003) Osteopontin induction is required for tumor promoter-induced transformation of preneoplastic mouse cells. Carcinogenesis 24:1749-1758
    • (2003) Carcinogenesis , vol.24 , pp. 1749-1758
    • Chang, P.L.1    Cao, M.2    Hicks, P.3
  • 33
    • 84855556875 scopus 로고    scopus 로고
    • Phase i I study of the mammalian target of rapamycin inhibitor ridaforolimus in patients with advanced bone and soft tissue sarcomas
    • Chawla SP, Staddon AP, Baker LH et al (2012) Phase I I study of the mammalian target of rapamycin inhibitor ridaforolimus in patients with advanced bone and soft tissue sarcomas. J Clin Oncol 30:78-84
    • (2012) J Clin Oncol , vol.30 , pp. 78-84
    • Chawla, S.P.1    Staddon, A.P.2    Baker, L.H.3
  • 34
    • 0027518307 scopus 로고
    • Differential effects of tumor necrosis factor-alpha on proliferation, cell surface antigen expression, and cytokine interactions in malignant gliomas
    • Chen TC, Hinton DR, Apuzzo ML et al (1993) Differential effects of tumor necrosis factor-alpha on proliferation, cell surface antigen expression, and cytokine interactions in malignant gliomas. Neurosurgery 32:85-94
    • (1993) Neurosurgery , vol.32 , pp. 85-94
    • Chen, T.C.1    Hinton, D.R.2    Apuzzo, M.L.3
  • 35
    • 33947146500 scopus 로고    scopus 로고
    • Mutation and expression analyses of the MET and CDKN2A genes in rhabdomyosarcoma with emphasis on MET overexpression
    • Chen Y, Takita J, Mizuguchi M et al (2007) Mutation and expression analyses of the MET and CDKN2A genes in rhabdomyosarcoma with emphasis on MET overexpression. Genes Chromosom Cancer 46:348-358
    • (2007) Genes Chromosom Cancer , vol.46 , pp. 348-358
    • Chen, Y.1    Takita, J.2    Mizuguchi, M.3
  • 36
    • 69249235848 scopus 로고    scopus 로고
    • Osteopontin increases migration and MMP-9 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cells
    • Chen YJ, Wei YY, Chen HT et al (2009) Osteopontin increases migration and MMP-9 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma cells. J Cell Physiol 2 21:98-108
    • (2009) J Cell Physiol , vol.221 , pp. 98-108
    • Chen, Y.J.1    Wei, Y.Y.2    Chen, H.T.3
  • 37
    • 33749165933 scopus 로고    scopus 로고
    • RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival
    • Chien Y, Kim S, Bumeister R et al (2006) RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival. Cell 127:157-170
    • (2006) Cell , vol.127 , pp. 157-170
    • Chien, Y.1    Kim, S.2    Bumeister, R.3
  • 38
    • 34249807879 scopus 로고    scopus 로고
    • Signal transduction pathways of GM-CSF in neural cell lines
    • Choi JK, Choi BH, Ha Y et al (2007) Signal transduction pathways of GM-CSF in neural cell lines. Neurosci Lett 420:217-222
    • (2007) Neurosci Lett , vol.420 , pp. 217-222
    • Choi, J.K.1    Choi, B.H.2    Ha, Y.3
  • 39
    • 84872869719 scopus 로고    scopus 로고
    • FOXM1 is an oncogenic mediator in Ewing sarcoma
    • Christensen L, Joo J, Lee S et al (2013) FOXM1 Is an oncogenic mediator in Ewing sarcoma. PLoS ONE 8:e54556
    • (2013) PLoS ONE , vol.8
    • Christensen, L.1    Joo, J.2    Lee, S.3
  • 40
    • 84871637412 scopus 로고    scopus 로고
    • Phase i study of doxorubicin D) plus anti-insulin-like growth factor 1 receptor (IGF-1R) a ntibody cixutumumab (IMC-A12) in advanced soft tissue sarcoma (STS
    • Chugh R, Griffith KA, Brockstein B et al (2012) Phase I study of doxorubicin (D) plus anti-insulin-like growth factor 1 receptor (IGF-1R) a ntibody cixutumumab (IMC-A12) in advanced soft tissue sarcoma (STS). J Clin Oncol 30:10028
    • (2012) J Clin Oncol , vol.30 , pp. 10028
    • Chugh, R.1    Griffith, K.A.2    Brockstein, B.3
  • 41
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
    • Colotta F, Allavena P, Sica A et al (2009) Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 30:1073-1081
    • (2009) Carcinogenesis , vol.30 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3
  • 42
    • 0026541255 scopus 로고
    • Differential expression of transforming growth factor-beta 1,-beta 2, and-beta 3 by glioblastoma cells, ast rocytes, and microglia
    • Constam DB, Philipp J, Malipiero UV et al (1992) Differential expression of transforming growth factor-beta 1,-beta 2, and-beta 3 by glioblastoma cells, ast rocytes, and microglia. J Immunol 148:1404-1410
    • (1992) J Immunol , vol.148 , pp. 1404-1410
    • Constam, D.B.1    Philipp, J.2    Malipiero, U.V.3
  • 43
    • 0028098165 scopus 로고
    • Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
    • Cordon-Cardo C, Latres E, Drobnjak M et al (1994) Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res 54:794-799
    • (1994) Cancer Res , vol.54 , pp. 794-799
    • Cordon-Cardo, C.1    Latres, E.2    Drobnjak, M.3
  • 44
    • 84856341746 scopus 로고    scopus 로고
    • Eribulin mesylate, a novel microtubule inhibitor in the treatment of breast cancer
    • Cortes J, Montero AJ, Gluck S (2012) Eribulin mesylate, a novel microtubule inhibitor in the treatment of breast cancer. Cancer Treat Rev 38:143-151
    • (2012) Cancer Treat Rev , vol.38 , pp. 143-151
    • Cortes, J.1    Montero, A.J.2    Gluck, S.3
  • 45
    • 79952487463 scopus 로고    scopus 로고
    • Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): A phase 3 open-label randomised study
    • Cortes J, O'Shaughnessy J, Loesch D et al (2011) Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study. Lancet 377:914-923
    • (2011) Lancet , vol.377 , pp. 914-923
    • Cortes, J.1    O'Shaughnessy, J.2    Loesch, D.3
  • 46
    • 79958857301 scopus 로고    scopus 로고
    • Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma
    • Crago AM, Singe r S (2011) Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma. Curr Opin Oncol 23:373-378
    • (2011) Curr Opin Oncol , vol.23 , pp. 373-378
    • Crago, A.M.1    Singe, R.S.2
  • 47
    • 80051617751 scopus 로고    scopus 로고
    • GM-CSF production by glioblastoma cel ls has a functional role in eosinophil survival, activation, and growth factor production for enhanced tumor cell proliferation
    • Curran CS, Evans MD, Bertics PJ (2011) GM-CSF production by glioblastoma cel ls has a functional role in eosinophil survival, activation, and growth factor production for enhanced tumor cell proliferation. J Immunol 187:1254-1263
    • (2011) J Immunol , vol.187 , pp. 1254-1263
    • Curran, C.S.1    Evans, M.D.2    Bertics, P.J.3
  • 48
    • 27244450145 scopus 로고    scopus 로고
    • Phase II study of doxorubicin and bevacizumab for patients with metastatic soft-tissue sarcomas
    • D'Adamo DR, Anderson SE, Albritton K et al (2005) Phase II study of doxorubicin and bevacizumab for patients with metastatic soft-tissue sarcomas. J Clin Oncol 23:7135-7142
    • (2005) J Clin Oncol , vol.23 , pp. 7135-7142
    • D'Adamo, D.R.1    Anderson, S.E.2    Albritton, K.3
  • 49
    • 34249010878 scopus 로고    scopus 로고
    • High prevalence of p53 exon 4 mutations in soft tissue sarcoma
    • Das P, Kotilinga m D, Korchin B et al (2007) High prevalence of p53 exon 4 mutations in soft tissue sarcoma. Cancer 109:2323-2333
    • (2007) Cancer , vol.109 , pp. 2323-2333
    • Das, P.1    Kotilinga, M.D.2    Korchin, B.3
  • 50
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta SR, Brunet A, Greenberg ME (1999) Cellular survival: a play in three Akts. Genes Dev 13:2905-2927
    • (1999) Genes Dev , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 51
    • 20944438542 scopus 로고    scopus 로고
    • Late radiation morbidity following randomization to preoperative versus postoperative radiotherapy in extremity soft tissue sa rcoma
    • Davis AM, O'Sullivan B, Turcotte R et al (2005) Late radiation morbidity following randomization to preoperative versus postoperative radiotherapy in extremity soft tissue sa rcoma. Radiother Oncol 75:48-53
    • (2005) Radiother Oncol , vol.75 , pp. 48-53
    • Davis, A.M.1    O'Sullivan, B.2    Turcotte, R.3
  • 52
    • 12144291080 scopus 로고    scopus 로고
    • Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointe stinal stromal tumours entered on phase i and II studies of the EORTC Soft Tissue and Bone Sarcoma Group
    • Debiec-Rychter M Dumez H Judson I et al 2004 Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointe stinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma Group Eur J Cancer 40:689-695
    • (2004) Eur J Cancer , vol.40 , pp. 689-695
    • Debiec-Rychter, M.1    Dumez, H.2    Judson, I.3
  • 53
    • 70249101414 scopus 로고    scopus 로고
    • Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: Results of a randomized phase II study of two different schedules
    • Demetri GD, Chawla SP, von Mehren M et al (2009a ) Efficacy and safety of trabectedin in patients with advanced or metastatic liposarcoma or leiomyosarcoma after failure of prior anthracyclines and ifosfamide: results of a randomized phase II study of two different schedules. J Clin Oncol 27:4188-4196
    • (2009) J Clin Oncol , vol.27 , pp. 4188-4196
    • Demetri, G.D.1    Chawla, S.P.2    Von Mehren, M.3
  • 54
    • 70349471245 scopus 로고    scopus 로고
    • Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure
    • Demetri GD, Heinrich MC, Fletcher JA et al (2009b ) Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure. Clin Cancer R es 15:5902-5909
    • (2009) Clin Cancer R Es , vol.15 , pp. 5902-5909
    • Demetri, G.D.1    Heinrich, M.C.2    Fletcher, J.A.3
  • 55
    • 0037103424 scopus 로고    scopus 로고
    • Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors
    • Demetri GD, von Mehren M, Blanke CD et al (2002) Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med 347:472-480
    • (2002) N Engl J Med , vol.347 , pp. 472-480
    • Demetri, G.D.1    Von Mehren, M.2    Blanke, C.D.3
  • 56
    • 65949118505 scopus 로고    scopus 로고
    • Mirk/Dyrk1B maintains the viability of quiescent pancreatic cancer cells by reducing levels of reactive oxygen species
    • Deng X, Ewton DZ, Friedman E (2009) Mirk/Dyrk1B maintains the viability of quiescent pancreatic cancer cells by reducing levels of reactive oxygen species. Cancer Res 69:3317-3324
    • (2009) Cancer Res , vol.69 , pp. 3317-3324
    • Deng, X.1    Ewton, D.Z.2    Friedman, E.3
  • 57
    • 84871563835 scopus 로고    scopus 로고
    • Phase II study of the HSP90-inhibitor BIIB021 in gastrointestinal stromal tumors
    • Dickson MA, Okuno SH , Keohan ML et al (2013) Phase II study of the HSP90-inhibitor BIIB021 in gastrointestinal stromal tumors. Ann Oncol 24:252-257
    • (2013) Ann Oncol , vol.24 , pp. 252-257
    • Dickson, M.A.1    Okuno, S.H.2    Keohan, M.L.3
  • 58
    • 41649100471 scopus 로고    scopus 로고
    • Mitogen-acti vated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma
    • Ding Y, Boguslawski EA, Berghuis BD et al (2008) Mitogen-acti vated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma. Mol Cancer Ther 7:648-658
    • (2008) Mol Cancer Ther , vol.7 , pp. 648-658
    • Ding, Y.1    Boguslawski, E.A.2    Berghuis, B.D.3
  • 59
    • 80051793013 scopus 로고    scopus 로고
    • MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1
    • doi:10.1186/1476-4598-10-99
    • Dong P, Kaneuchi M, Watari H et al (2011) MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1. Mol Cancer 10:99. doi:10.1186/1476-4598-10-99
    • (2011) Mol Cancer , vol.10 , pp. 99
    • Dong, P.1    Kaneuchi, M.2    Watari, H.3
  • 60
    • 84859642925 scopus 로고    scopus 로고
    • Kaposi sarcoma pathogenesis: A triad of viral infection, oncogenesis and chronic inflammation
    • Douglas JL, Gustin JK, Moses AV et al (2010) Kaposi sarcoma pathogenesis: a triad of viral infection, oncogenesis and chronic inflammation. Transl Biomed 1:pii 172
    • (2010) Transl Biomed , vol.1
    • Douglas, J.L.1    Gustin, J.K.2    Moses, A.V.3
  • 61
    • 70449096105 scopus 로고    scopus 로고
    • Cancer: A tumour gen e's fatal flaws
    • Downward J (2009) Cancer: a tumour gen e's fatal flaws. Nature 462:44-45
    • (2009) Nature , vol.462 , pp. 44-45
    • Downward, J.1
  • 62
    • 84874471799 scopus 로고    scopus 로고
    • Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth
    • Edris B, Wi llingham SB, Weiskopf K et al (2013) Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth. Proc Natl Acad Sci USA 110:3501-3506
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 3501-3506
    • Edris, B.1    Wi Llingham, S.B.2    Weiskopf, K.3
  • 63
    • 77951231349 scopus 로고    scopus 로고
    • MT or and cancer: Many loops in one pathway
    • Efeyan A, Sabatini DM (2010) mT OR and cancer: many loops in one pathway. Curr Opin Cell Biol 22:169-176
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 169-176
    • Efeyan, A.1    Sabatini, D.M.2
  • 64
    • 79952770962 scopus 로고    scopus 로고
    • Diamond Blackfan anemia: Ribosomal proteins going rogue
    • Ellis SR, Gleizes PE (2011) Diamond Blackfan anemia: ribosomal proteins going rogue. Semin Hematol 48:89-96
    • (2011) Semin Hematol , vol.48 , pp. 89-96
    • Ellis, S.R.1    Gleizes, P.E.2
  • 65
    • 77952016845 scopus 로고    scopus 로고
    • Gauchos and ochos: A Wee1-Cdk tango regulating mitotic entry
    • doi:10.1186/1747-1028-5-12
    • Enders GH (2010) Gauchos and ochos: a Wee1-Cdk tango regulating mitotic entry. Cell Div 5:12. doi:10.1186/1747-1028-5-12
    • (2010) Cell Div , vol.5 , pp. 12
    • Enders, G.H.1
  • 66
    • 84872546604 scopus 로고    scopus 로고
    • Prognostic Significance of AKT/mTO R and MAPK Pathways and Antitumor Effect of mTOR Inhibitor in NF1-Related and Sporadic Malignant Peripheral Nerve Sheath Tumors
    • Endo M, Yamamoto H, Setsu N et al (2013) Prognostic Significance of AKT/mTO R and MAPK Pathways and Antitumor Effect of mTOR Inhibitor in NF1-Related and Sporadic Malignant Peripheral Nerve Sheath Tumors. Clin Cancer Res 19:450-461
    • (2013) Clin Cancer Res , vol.19 , pp. 450-461
    • Endo, M.1    Yamamoto, H.2    Setsu, N.3
  • 67
    • 64549149292 scopus 로고    scopus 로고
    • Notch signaling contributes to the pathogenesis of human osteosarcomas
    • Engin F, Bertin T, Ma O et al (2009) Notch signaling contributes to the pathogenesis of human osteosarcomas. Hum Mol Genet 18:1464-1470
    • (2009) Hum Mol Genet , vol.18 , pp. 1464-1470
    • Engin, F.1    Bertin, T.2    Ma, O.3
  • 68
    • 72949097617 scopus 로고    scopus 로고
    • Regulation of the endothelial cell cycle by the ubiquitin-proteasome system
    • Fasanaro P, Capogrossi MC, Martelli F (2010) Regulation of the endothelial cell cycle by the ubiquitin-proteasome system. Cardiovasc Res 85:272-280
    • (2010) Cardiovasc Res , vol.85 , pp. 272-280
    • Fasanaro, P.1    Capogrossi, M.C.2    Martelli, F.3
  • 69
    • 0033571557 scopus 로고    scopus 로고
    • Paclitaxel in the treatment of patients with angiosarcoma of the scalp or face
    • Fata F, O'Reilly E, Ilson D et al (1999) Paclitaxel in the treatment of patients with angiosarcoma of the scalp or face. Cancer 86:2034-2037
    • (1999) Cancer , vol.86 , pp. 2034-2037
    • Fata, F.1    O'Reilly, E.2    Ilson, D.3
  • 70
    • 0035871306 scopus 로고    scopus 로고
    • Serum endostatin levels are elevated in patients with soft tissue sarcoma
    • Feldman AL, Pak H, Yang JC et al (2001) Serum endostatin levels are elevated in patients with soft tissue sarcoma. Cancer 91:1525-1529
    • (2001) Cancer , vol.91 , pp. 1525-1529
    • Feldman, A.L.1    Pak, H.2    Yang, J.C.3
  • 71
    • 84872448128 scopus 로고    scopus 로고
    • A pilot study of low-dose anti-angiogenic chemotherapy in combination with standard multiagent chemotherapy for patients with newly diagnosed metastatic Ewing sarcoma family of tumors: A Children's Oncology Group (COG) Phase II study NCT00061893
    • Felgenhauer JL, Nieder ML, Krailo MD et al (2013) A pilot study of low-dose anti-angiogenic chemotherapy in combination with standard multiagent chemotherapy for patients with newly diagnosed metastatic Ewing sarcoma family of tumors: A Children's Oncology Group (COG) Phase II study NCT00061893. Pediatr Bl ood Cancer 60:409-414
    • (2013) Pediatr Bl Ood Cancer , vol.60 , pp. 409-414
    • Felgenhauer, J.L.1    Nieder, M.L.2    Krailo, M.D.3
  • 72
    • 77957143607 scopus 로고    scopus 로고
    • The increased expression of receptor activator of nuclear-kappaB ligand (RANKL) of multiple myeloma bone marrow stromal cells is inhibited by th e bisphosphonate ibandronate
    • Fernandez M, Pino AM, Figueroa P et al (2010) The increased expression of receptor activator of nuclear-kappaB ligand (RANKL) of multiple myeloma bone marrow stromal cells is inhibited by th e bisphosphonate ibandronate. J Cell Biochem 111:130-137
    • (2010) J Cell Biochem , vol.111 , pp. 130-137
    • Fernandez, M.1    Pino, A.M.2    Figueroa, P.3
  • 73
  • 74
    • 80052664254 scopus 로고    scopus 로고
    • Soft tissue sarcoma across the age spectrum: A populationbased study from the surveillance epidemiology and end results database
    • Ferrari A, Sultan I, Huang TT et al (2011) Soft tissue sarcoma across the age spectrum: a populationbased study from the surveillance epidemiology and end results database. Pediatr Blood Cancer 57:943-949
    • (2011) Pediatr Blood Cancer , vol.57 , pp. 943-949
    • Ferrari, A.1    Sultan, I.2    Huang, T.T.3
  • 75
    • 1542318327 scopus 로고    scopus 로고
    • Lifetime risks of common cancers among retinoblastoma survivors
    • Fletcher O, Easton D, Anderson K et al (2004) Lifetime risks of common cancers among retinoblastoma survivors. J Natl Cancer Inst 96:357-363
    • (2004) J Natl Cancer Inst , vol.96 , pp. 357-363
    • Fletcher, O.1    Easton, D.2    Anderson, K.3
  • 76
    • 0021344432 scopus 로고
    • Glioblastoma cells release interleukin 1 and factors inhibiting interleukin 2-mediated effects
    • Fontana A, Hengartner H, de Tribolet N et al (1984) Glioblastoma cells release interleukin 1 and factors inhibiting interleukin 2-mediated effects. J Immunol 132:1837-1844
    • (1984) J Immunol , vol.132 , pp. 1837-1844
    • Fontana, A.1    Hengartner, H.2    De Tribolet, N.3
  • 77
    • 78651330430 scopus 로고    scopus 로고
    • COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
    • Forbes SA, Bind al N, Bamford S et al (2011) COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res 39:D945-D950
    • (2011) Nucleic Acids Res , vol.39
    • Forbes, S.A.1    Bindal, N.2    Bamford, S.3
  • 78
    • 0029785175 scopus 로고    scopus 로고
    • Kaposi's sarcoma tumor cells preferentially express Bcl-xL
    • Foreman KE, Wrone-Smith T, Boise LH et al (1996) Kaposi's sarcoma tumor cells preferentially express Bcl-xL. Am J Pathol 149:795-803
    • (1996) Am J Pathol , vol.149 , pp. 795-803
    • Foreman, K.E.1    Wrone-Smith, T.2    Boise, L.H.3
  • 79
    • 0026506708 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor (GM-CSF) production by glioblas toma cells. Despite the presence of inducing signals GM-CSF is not expressed in vivo
    • Frei K, Piani D, Malipiero UV et al (1992) Granulocyte-macrophage colony-stimulating factor (GM-CSF) production by glioblas toma cells. Despite the presence of inducing signals GM-CSF is not expressed in vivo. J Immunol 148:3140-3146
    • (1992) J Immunol , vol.148 , pp. 3140-3146
    • Frei, K.1    Piani, D.2    Malipiero, U.V.3
  • 80
    • 79959368860 scopus 로고    scopus 로고
    • The role of mirk kinase in sarcomas
    • doi:10.1155/2011/260757
    • Friedman E (2011) The role of mirk kinase in sarcomas. Sarcoma 2011:260757. doi:10.1155/2011/260757
    • (2011) Sarcoma , vol.2011 , pp. 260757
    • Friedman, E.1
  • 81
    • 57149093206 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma
    • Friedrichs N, Kuchler J, Endl E et al (2008) Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma. J Pathol 216:428-439
    • (2008) J Pathol , vol.216 , pp. 428-439
    • Friedrichs, N.1    Kuchler, J.2    Endl, E.3
  • 82
    • 79958716819 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor SCH 727965 (dinacliclib) induces the apoptosis of osteosarcoma cells
    • Fu W, Ma L, Chu B et al (2011) The cyclin-dependent kinase inhibitor SCH 727965 (dinacliclib) induces the apoptosis of osteosarcoma cells. Mol Cancer Ther 10:1018-1027
    • (2011) Mol Cancer Ther , vol.10 , pp. 1018-1027
    • Fu, W.1    Ma, L.2    Chu, B.3
  • 83
    • 0034777791 scopus 로고    scopus 로고
    • Ovarian fibrosarcoma producing multiple cytokines
    • Fukuda T, Yamaguchi T, Yamaki T et al (2001) Ovarian fibrosarcoma producing multiple cytokines. Pathol Int 51:739-743
    • (2001) Pathol Int , vol.51 , pp. 739-743
    • Fukuda, T.1    Yamaguchi, T.2    Yamaki, T.3
  • 84
    • 77956717395 scopus 로고    scopus 로고
    • Dramatic improvement of inoperable angiosarcoma with combination paclitaxel an d bevacizumab chemotherapy
    • Fuller CK, Charlson JA, Dankle SK et al (2010) Dramatic improvement of inoperable angiosarcoma with combination paclitaxel an d bevacizumab chemotherapy. J Am Acad Dermatol 63:e83-e84
    • (2010) J Am Acad Dermatol , vol.63
    • Fuller, C.K.1    Charlson, J.A.2    Dankle, S.K.3
  • 85
    • 70349783544 scopus 로고    scopus 로고
    • Tyrosines in the kinesin-5 head domain are necessary for phosphorylation by Wee1 and for mitotic spin dle integrity
    • Garcia K, Stumpff J, Duncan T et al (2009) Tyrosines in the kinesin-5 head domain are necessary for phosphorylation by Wee1 and for mitotic spin dle integrity. Curr Biol 19:1670-1676
    • (2009) Curr Biol , vol.19 , pp. 1670-1676
    • Garcia, K.1    Stumpff, J.2    Duncan, T.3
  • 86
    • 2342461682 scopus 로고    scopus 로고
    • Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues re fractory to chemotherapy
    • Garcia-Carbonero R, Supko JG, Manola J et al (2004) Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues re fractory to chemotherapy. J Clin Oncol 22:1480-1490
    • (2004) J Clin Oncol , vol.22 , pp. 1480-1490
    • Garcia-Carbonero, R.1    Supko, J.G.2    Manola, J.3
  • 87
    • 76749118404 scopus 로고    scopus 로고
    • Activity of cediranib, a highly potent and selective VEGF signaling inhibitor, in alveolar soft part sarcoma
    • Gardner K, Judson I, Leahy M et al (2009) Activity of cediranib, a highly potent and selective VEGF signaling inhibitor, in alveolar soft part sarcoma . J Clin Oncol 27:10523. http://meeting.ascopubs.org/cgi/content/abstract/27/15S/ 10523?sid=cbb7 71a3-21c0-4634-955b-60ff724c1f3a
    • (2009) J Clin Oncol , vol.27 , pp. 10523
    • Gardner, K.1    Judson, I.2    Leahy, M.3
  • 88
    • 78751527395 scopus 로고    scopus 로고
    • Selective inhibition of cyclo oxygenase-2 suppresses metastatic disease without affecting primary tumor growth in a murine model of Ewing sarcoma
    • Gendy AS, Lipskar A, Glick RD et al (2011) Selective inhibition of cyclo oxygenase-2 suppresses metastatic disease without affecting primary tumor growth in a murine model of Ewing sarcoma. J Pediatr Surg 46:108-114
    • (2011) J Pediatr Surg , vol.46 , pp. 108-114
    • Gendy, A.S.1    Lipskar, A.2    Glick, R.D.3
  • 89
    • 84869160236 scopus 로고    scopus 로고
    • Successful treat ment with the mTOR inhibitor everolimus in a patient with perivascular epithelioid cell tumor
    • Gennatas C, Michalaki V, Kairi PV et al (2012) Successful treat ment with the mTOR inhibitor everolimus in a patient with perivascular epithelioid cell tumor. World J Surg Oncol 10:181
    • (2012) World J Surg Oncol , vol.10 , pp. 181
    • Gennatas, C.1    Michalaki, V.2    Kairi, P.V.3
  • 90
    • 67249147869 scopus 로고    scopus 로고
    • Clinical evaluation of continuous daily dosing of sunitinib malate in patients with advanced gastrointestinal stromal tumour after imatinib failure
    • George S, Blay JY, Casali PG et al (2009) Clinical evaluation of continuous daily dosing of sunitinib malate in patients with advanced gastrointestinal stromal tumour after imatinib failure. Eur J Cancer 45:19 59-1968
    • (2009) Eur J Cancer , vol.45 , pp. 1959-1968
    • George, S.1    Blay, J.Y.2    Casali, P.G.3
  • 91
    • 18244383816 scopus 로고    scopus 로고
    • Differentially amplified chromosome 12 sequences in low-and high-grade osteosarcoma
    • Gisselsson D, Palsson E, Hoglund M et al (2002) Differentially amplified chromosome 12 sequences in low-and high-grade osteosarcoma. Genes Chromosom Cancer 33:133-140
    • (2002) Genes Chromosom Cancer , vol.33 , pp. 133-140
    • Gisselsson, D.1    Palsson, E.2    Hoglund, M.3
  • 92
    • 70350061991 scopus 로고    scopus 로고
    • Chondrosarcoma in the United States 1973-2003): An analysis of 2,890 cases from the SEER database
    • Giuffrida A Y, Burgueno JE, Koniaris LG et al (2009) Chondrosarcoma in the United States (1973-2003): an analysis of 2,890 cases from the SEER database. J Bone Joint Surg Am 91:1063-1072
    • (2009) J Bone Joint Surg Am , vol.91 , pp. 1063-1072
    • Giuffrida, A.Y.1    Burgueno, J.E.2    Koniaris, L.G.3
  • 93
    • 84856343533 scopus 로고    scopus 로고
    • A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: An Italian Sarcoma Group study
    • Grignani G, Palmer ini E, Dileo P et al (2012) A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study. Ann Oncol 23:508-516
    • (2012) Ann Oncol , vol.23 , pp. 508-516
    • Grignani, G.1    Palmer Ini, E.2    Dileo, P.3
  • 94
    • 79952215751 scopus 로고    scopus 로고
    • UK guidelines for the management of bone sarcomas
    • doi:10.1155/2010/317462
    • Grimer R, Athanasou N, Gerrand C et al (2010a) UK guidelines for the management of bone sarcomas. Sarcoma 2010:317462. doi:10.1155/2010/317462
    • (2010) Sarcoma , vol.2010 , pp. 317462
    • Grimer, R.1    Athanasou, N.2    Gerrand, C.3
  • 95
    • 77953502245 scopus 로고    scopus 로고
    • Guidelines for the management of soft tissue sarcomas
    • doi:10.1155/2010/506182
    • Grimer R, Judson I, Peake D et al (2010b) Guidelines for the management of soft tissue sarcomas. Sarcoma 2010:506182. doi:10.1155/2010/506182
    • (2010) Sarcoma , vol.2010 , pp. 506182
    • Grimer, R.1    Judson, I.2    Peake, D.3
  • 96
    • 77951007582 scopus 로고    scopus 로고
    • The role of high-dose imatinib in the management of patients with gastrointestinal stromal tumor
    • Gronchi A, Blay JY, Trent JC (2010) The role of high-dose imatinib in the management of patients with gastrointestinal stromal tumor. Cancer 116:1847-1858
    • (2010) Cancer , vol.116 , pp. 1847-1858
    • Gronchi, A.1    Blay, J.Y.2    Trent, J.C.3
  • 97
    • 84857530639 scopus 로고    scopus 로고
    • Phase II clinical trial of neoadjuvant trabectedin in patients with advanced localized myxoid liposarcoma
    • Gronchi A, Bui BN, Bonvalot S et al (2012) Phase II clinical trial of neoadjuvant trabectedin in patients with advanced localized myxoid liposarcoma. Ann Oncol 23:771-776
    • (2012) Ann Oncol , vol.23 , pp. 771-776
    • Gronchi, A.1    Bui, B.N.2    Bonvalot, S.3
  • 98
    • 51049114726 scopus 로고    scopus 로고
    • Targeting Lyn inhibits tumor growth and metastasis in Ewing's sarcoma
    • Guan H, Zhou Z, Gallick GE et al (2008) Targeting Lyn inhibits tumor growth and metastasis in Ewing's sarcoma. Mol Cancer Ther 7:1807-1816
    • (2008) Mol Cancer Ther , vol.7 , pp. 1807-1816
    • Guan, H.1    Zhou, Z.2    Gallick, G.E.3
  • 99
    • 23144467910 scopus 로고    scopus 로고
    • An expanding role for mTOR in cancer
    • Guertin DA, Sabatini DM (2005) An expanding role for mTOR in cancer. Trends Mol Med 11:353-361
    • (2005) Trends Mol Med , vol.11 , pp. 353-361
    • Guertin, D.A.1    Sabatini, D.M.2
  • 100
    • 84877113871 scopus 로고    scopus 로고
    • Systematic chemotherapy for inoperable, locally advanced, recurrent, or metastatic uterine leiomyosarcoma: A systematic review
    • Gupta AA, Yao X, Verma S et al (2013) Systematic chemotherapy for inoperable, locally advanced, recurrent, or metastatic uterine leiomyosarcoma: a systematic review. Clin Oncol (R Coll Radiol) 25:346-355
    • (2013) Clin Oncol (R Coll Radiol , vol.25 , pp. 346-355
    • Gupta, A.A.1    Yao, X.2    Verma, S.3
  • 101
    • 39049183044 scopus 로고    scopus 로고
    • Regulation and function of IKK and IKK-related kinases
    • Hacker H, Karin M (2006) Regulation and function of IKK and IKK-related kinases. Sci STKE 2006:re13
    • (2006) Sci STKE , vol.2006
    • Hacker, H.1    Karin, M.2
  • 102
    • 33748751685 scopus 로고    scopus 로고
    • Green tea polyphenols-induced apoptosis in human osteosarco ma SAOS-2 cells involves a caspase-dependent mechanism with downregulation of nuclear factor-kappaB
    • Hafeez BB, Ahmed S, Wang N et al (2006) Green tea polyphenols-induced apoptosis in human osteosarco ma SAOS-2 cells involves a caspase-dependent mechanism with downregulation of nuclear factor-kappaB. Toxicol Appl Pharmacol 216:11-19
    • (2006) Toxicol Appl Pharmacol , vol.216 , pp. 11-19
    • Hafeez, B.B.1    Ahmed, S.2    Wang, N.3
  • 103
    • 84859133038 scopus 로고    scopus 로고
    • Prognostic impact of mRNA levels of osteopontin splice variants in soft tissue sarcoma patients
    • doi:10.1186/1471-2407-12-131
    • Hahnel A, Wichmann H, Greither T et al (2012) Prognostic impact of mRNA levels of osteopontin splice variants in soft tissue sarcoma patients. BMC Cancer 12:131. doi:10.1186/1471-2407-12-131
    • (2012) BMC Cancer , vol.12 , pp. 131
    • Hahnel, A.1    Wichmann, H.2    Greither, T.3
  • 104
    • 0022402666 scopus 로고
    • Osteosarcoma and retinoblastoma: A shared chromosomal mechanism revealing recessive predisposition
    • Hansen MF, Koufos A, Gallie BL et al (1985) Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition. Proc Natl Acad Sci USA 82:6216-6220
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 6216-6220
    • Hansen, M.F.1    Koufos, A.2    Gallie, B.L.3
  • 105
    • 84979129316 scopus 로고
    • Chronische und akute Entzündungen als Ursache für Sarkom
    • Harbitz F (1924) Chronische und akute Entzündungen als Ursache für Sarkom. Acta Pathol Microbiol Scand 1:438-447
    • (1924) Acta Pathol Microbiol Scand , vol.1 , pp. 438-447
    • Harbitz, F.1
  • 106
    • 0034762772 scopus 로고    scopus 로고
    • Molecular basis of low-penetrance retinoblastoma
    • Harbour JW (2001) Molecular basis of low-penetrance retinoblastoma. Arch Ophthalmol 119:1699-1704
    • (2001) Arch Ophthalmol , vol.119 , pp. 1699-1704
    • Harbour, J.W.1
  • 107
    • 33846608696 scopus 로고    scopus 로고
    • Cell cycle regulation by the Wee1 inhibitor PD0166285, pyrido [2,3-d] pyimidine, in the B16 mouse melanoma cell line
    • doi:10.1186/1471-2407-6-292
    • Hashimoto O, Shinkawa M, To rimura T et al (2006) Cell cycle regulation by the Wee1 inhibitor PD0166285, pyrido [2,3-d] pyimidine, in the B16 mouse melanoma cell line. BMC Cancer 6:292. doi:10.1186/1471-2407-6-292
    • (2006) BMC Cancer , vol.6 , pp. 292
    • Hashimoto, O.1    Shinkawa, M.2    To Rimura, T.3
  • 108
    • 84856220447 scopus 로고    scopus 로고
    • Cell surface receptor expression patterns in osteosarcoma
    • Hassan SE, Beka rev M, Kim MY et al (2012) Cell surface receptor expression patterns in osteosarcoma. Cancer 118:740-749
    • (2012) Cancer , vol.118 , pp. 740-749
    • Hassan, S.E.1    Beka Rev, M.2    Kim, M.Y.3
  • 109
    • 0026555721 scopus 로고
    • Retroviral infection accelerates T lymphomagenesis in e mu-N-ras transgenic mice by activating c-myc or N-myc
    • Haupt Y, Harris AW, Adams JM (1992) Retroviral infection accelerates T lymphomagenesis in E mu-N-ras transgenic mice by activating c-myc or N-myc. Oncogene 7:981-986
    • (1992) Oncogene , vol.7 , pp. 981-986
    • Haupt, Y.1    Harris, A.W.2    Adams, J.M.3
  • 110
    • 84862813636 scopus 로고    scopus 로고
    • Effective oncolytic vaccinia therapy for human sarcomas
    • He S, Li P, Chen CH et al (2012) Effective oncolytic vaccinia therapy for human sarcomas. J Surg Res 175:e53-e60
    • (2012) J Surg Res , vol.175
    • He, S.1    Li, P.2    Chen, C.H.3
  • 111
    • 0642368571 scopus 로고    scopus 로고
    • Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
    • Heinrich MC, Corless CL, Demetri GD et al (2003a ) Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J Clin Oncol 21:4342-4349
    • (2003) J Clin Oncol , vol.21 , pp. 4342-4349
    • Heinrich, M.C.1    Corless, C.L.2    Demetri, G.D.3
  • 112
    • 0242670019 scopus 로고    scopus 로고
    • PDGFRA activating mutations in gastrointestinal stromal tumors
    • Heinrich MC, Corless CL, Duensing A et al (2003b ) PDGFRA activating mutations in gastrointestinal stromal tumors. Science 299:708-710
    • (2003) Science , vol.299 , pp. 708-710
    • Heinrich, M.C.1    Corless, C.L.2    Duensing, A.3
  • 113
    • 56749098278 scopus 로고    scopus 로고
    • Primary an d secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor
    • Heinrich MC, Maki RG, Corless CL et al (2008) Primary an d secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor. J Clin Oncol 26:5352-5359
    • (2008) J Clin Oncol , vol.26 , pp. 5352-5359
    • Heinrich, M.C.1    Maki, R.G.2    Corless, C.L.3
  • 114
    • 34447326491 scopus 로고    scopus 로고
    • Determination of the prognostic value of loss of heterozygosity at the retinoblastoma gene in osteosarcoma
    • Heinsohn S, Evermann U, Zur SU et al (2007) Determination of the prognostic value of loss of heterozygosity at the retinoblastoma gene in osteosarcoma. Int J Oncol 30:1205-1214
    • (2007) Int J Oncol , vol.30 , pp. 1205-1214
    • Heinsohn, S.1    Evermann, U.2    Zur, S.U.3
  • 115
    • 44449135941 scopus 로고    scopus 로고
    • Fixe d-dose rate gemcitabine plus docetaxel as second-line therapy for metastatic uterine leiomyosarcoma: A Gynecologic Oncology Group phase II study
    • Hensley ML, Blessing JA, Degeest K et al (2008a ) Fixe d-dose rate gemcitabine plus docetaxel as second-line therapy for metastatic uterine leiomyosarcoma: a Gynecologic Oncology Group phase II study. Gynecol Oncol 109:323-328
    • (2008) Gynecol Oncol , vol.109 , pp. 323-328
    • Hensley, M.L.1    Blessing, J.A.2    Degeest, K.3
  • 116
    • 44449096592 scopus 로고    scopus 로고
    • Fixed-dose rate gemcitabine plus docetaxel as first-line therapy for metastatic uterine leiomyosarcoma: A Gynecologic Oncology Group phase II trial
    • Hensley ML, Blessing JA, Mannel R et al (2008b ) Fixed-dose rate gemcitabine plus docetaxel as first-line therapy for metastatic uterine leiomyosarcoma: a Gynecologic Oncology Group phase II trial. Gynecol Oncol 109:329-334
    • (2008) Gynecol Oncol , vol.109 , pp. 329-334
    • Hensley, M.L.1    Blessing, J.A.2    Mannel, R.3
  • 117
    • 34250013899 scopus 로고    scopus 로고
    • The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas
    • Hernando E Charytonowicz E Dudas ME et al 2007 The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas Nat Med 13: 748-753
    • (2007) Nat Med , vol.13 , pp. 748-753
    • Hernando, E.1    Charytonowicz, E.2    Dudas, M.E.3
  • 118
    • 84055178989 scopus 로고    scopus 로고
    • Sarcomas induced in discrete subsets of prospectively isolated skeletal muscle cells
    • Hettmer S, Liu J, Miller CM et al (2011) Sarcomas induced in discrete subsets of prospectively isolated skeletal muscle cells. Proc Natl Acad Sci USA 108:20002-20007
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 20002-20007
    • Hettmer, S.1    Liu, J.2    Miller, C.M.3
  • 119
    • 77956247365 scopus 로고    scopus 로고
    • Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft model
    • Hillegass JM, Shukla A, Lathrop SA et al (2010a) Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft model. Ann NY Acad Sci 1203:7-14
    • (2010) Ann NY Acad Sci , vol.1203 , pp. 7-14
    • Hillegass, J.M.1    Shukla, A.2    Lathrop, S.A.3
  • 120
    • 77149177975 scopus 로고    scopus 로고
    • Utilization of gene profiling and proteomics to determine mineral pathogenicity in a human mesothelial cell line (LP9/TERT-1
    • Hillegass JM, Shukla A, MacPherson MB et al (2010b) Utilization of gene profiling and proteomics to determine mineral pathogenicity in a human mesothelial cell line (LP9/TERT-1). J Toxicol Environ Health A 73:423-436
    • (2010) J Toxicol Environ Health A , vol.73 , pp. 423-436
    • Hillegass, J.M.1    Shukla, A.2    Macpherson, M.B.3
  • 121
    • 0029859402 scopus 로고    scopus 로고
    • Overexpression of bcl-2 protein in synovial sarcoma: A comparative study of other soft tissue spindle cell sarcomas and an additional analysis by fluorescence in situ hybridization
    • Hirakaw a N, Naka T, Yamamoto I et al (1996) Overexpression of bcl-2 protein in synovial sarcoma: a comparative study of other soft tissue spindle cell sarcomas and an additional analysis by fluorescence in situ hybridization. Hum Pathol 27:1060-1065
    • (1996) Hum Pathol , vol.27 , pp. 1060-1065
    • Hirakaw, A.N.1    Naka, T.2    Yamamoto, I.3
  • 122
    • 0142026839 scopus 로고    scopus 로고
    • Osteopontin overproduced by tumor cells acts as a potent angiogenic factor contributing to tumor growth
    • Hirama M, Takahashi F, Takahashi K et al (2003) Osteopontin overproduced by tumor cells acts as a potent angiogenic factor contributing to tumor growth. Cancer Lett 198:107-117
    • (2003) Cancer Lett , vol.198 , pp. 107-117
    • Hirama, M.1    Takahashi, F.2    Takahashi, K.3
  • 123
    • 0033104753 scopus 로고    scopus 로고
    • Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1
    • Hiromura K, Pippin JW, Fero ML et al (1999) Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1). J Clin Invest 103:597-604
    • (1999) J Clin Invest , vol.103 , pp. 597-604
    • Hiromura, K.1    Pippin, J.W.2    Fero, M.L.3
  • 124
    • 78650958694 scopus 로고    scopus 로고
    • Identification of altered MicroRNA expression patterns in synovial sarcoma
    • Hisaoka M, Matsuyama A, Nagao Y et al (2011) Identification of altered MicroRNA expression patterns in synovial sarcoma. Genes Chromosom Cancer 50:137-145
    • (2011) Genes Chromosom Cancer , vol.50 , pp. 137-145
    • Hisaoka, M.1    Matsuyama, A.2    Nagao, Y.3
  • 125
    • 84865722534 scopus 로고    scopus 로고
    • PDGF receptor alpha is an alternati ve mediator of rapamycin-induced Akt activation: Implications for combination targeted therapy of synovial sarcoma
    • Ho AL, Vasudeva SD, Lae M et al (2012) PDGF receptor alpha is an alternati ve mediator of rapamycin-induced Akt activation: implications for combination targeted therapy of synovial sarcoma. Cancer Res 72:4515-4525
    • (2012) Cancer Res , vol.72 , pp. 4515-4525
    • Ho, A.L.1    Vasudeva, S.D.2    Lae, M.3
  • 126
    • 3142647035 scopus 로고    scopus 로고
    • Changing concepts in the pathological basis of soft tissue and bone sarcoma treatment
    • Hogendoorn PC, Collin F, Daugaard S et al (2004) Changing concepts in the pathological basis of soft tissue and bone sarcoma treatment. Eur J Cancer 40:1644-1654
    • (2004) Eur J Cancer , vol.40 , pp. 1644-1654
    • Hogendoorn, P.C.1    Collin, F.2    Daugaard, S.3
  • 127
    • 33845609557 scopus 로고    scopus 로고
    • INOS-dependent DNA damage in patients with malignant fibrous histiocytoma in relation to prognosis
    • Hoki Y, Hiraku Y, Ma N et al (2007a ) iNOS-dependent DNA damage in patients with malignant fibrous histiocytoma in relation to prognosis. Cancer Sci 98:163-168
    • (2007) Cancer Sci , vol.98 , pp. 163-168
    • Hoki, Y.1    Hiraku, Y.2    Ma, N.3
  • 128
    • 38449111153 scopus 로고    scopus 로고
    • 8-Nitroguanine as a potential biomarker for progression of malignant fibrous histiocytoma, a model of inflammation-related cancer
    • Hoki Y, Murata M, Hiraku Y et al (2007b ) 8-Nitroguanine as a potential biomarker for progression of malignant fibrous histiocytoma, a model of inflammation-related cancer. Oncol Rep 18:1165-1169
    • (2007) Oncol Rep , vol.18 , pp. 1165-1169
    • Hoki, Y.1    Murata, M.2    Hiraku, Y.3
  • 129
    • 84863582759 scopus 로고    scopus 로고
    • Combined administration of EGCG and IL-1 receptor antagonist efficiently downregulates IL-1-induced tumorigenic factors in U-2 OS human osteosarcoma cells
    • Hö nicke AS, Ender SA, Radons J (2012) Combined administration of EGCG and IL-1 receptor antagonist efficiently downregulates IL-1-induced tumorigenic factors in U-2 OS human osteosarcoma cells. Int J Oncol 41:753-758
    • (2012) Int J Oncol , vol.41 , pp. 753-758
    • Hö Nicke, A.S.1    Ender, S.A.2    Radons, J.3
  • 130
    • 33645869265 scopus 로고    scopus 로고
    • Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases
    • Honma M, Higuchi O, Shirakata M et al (2006) Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases. Genes Cells 11:143-151
    • (2006) Genes Cells , vol.11 , pp. 143-151
    • Honma, M.1    Higuchi, O.2    Shirakata, M.3
  • 131
    • 40449091406 scopus 로고    scopus 로고
    • Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program
    • Houghton PJ, Morton CL, Kolb EA et al (2008) Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program. Pediatr Blood Cancer 50:799-805
    • (2008) Pediatr Blood Cancer , vol.50 , pp. 799-805
    • Houghton, P.J.1    Morton, C.L.2    Kolb, E.A.3
  • 132
    • 31544465982 scopus 로고    scopus 로고
    • Skp2 overexpression is highly representative of intrinsic biological aggressiveness and independently associated with poor prognosis in primary localized myxofibrosarc omas
    • Huang HY, Kang HY, Li CF et al (2006) Skp2 overexpression is highly representative of intrinsic biological aggressiveness and independently associated with poor prognosis in primary localized myxofibrosarc omas. Clin Cancer Res 12:487-498
    • (2006) Clin Cancer Res , vol.12 , pp. 487-498
    • Huang, H.Y.1    Kang, H.Y.2    Li, C.F.3
  • 133
    • 34247877666 scopus 로고    scopus 로고
    • GM-CSF inhibits apoptosis of neural cells via regulating the expression of apoptosis-related proteins
    • Huang X, Choi JK, Park SR et al (2007) GM-CSF inhibits apoptosis of neural cells via regulating the expression of apoptosis-related proteins. Neurosci Res 58:50-57
    • (2007) Neurosci Res , vol.58 , pp. 50-57
    • Huang, X.1    Choi, J.K.2    Park, S.R.3
  • 134
    • 35648983903 scopus 로고    scopus 로고
    • Inflammation and cancer: An ancient link with novel potentials
    • Hussain SP, Harris CC (2007) Inflammation and cancer: an ancient link with novel potentials. Int J Cancer 121:2373-2380
    • (2007) Int J Cancer , vol.121 , pp. 2373-2380
    • Hussain, S.P.1    Harris, C.C.2
  • 135
    • 0025857198 scopus 로고
    • Prognosis of children with virus-associated hemophagocytic syndrome and malignant histiocytosis: Correlation with levels of serum interleukin-1 and tumor necrosis factor
    • Ishii E, Ohga S, Aoki T et al (1991) Prognosis of children with virus-associated hemophagocytic syndrome and malignant histiocytosis: correlation with levels of serum interleukin-1 and tumor necrosis factor. Acta Haematol 85:93-99
    • (1991) Acta Haematol , vol.85 , pp. 93-99
    • Ishii, E.1    Ohga, S.2    Aoki, T.3
  • 136
    • 77953341782 scopus 로고    scopus 로고
    • Treatment with the mTOR inhibitor temsirolimus in patients with malignant PEComa
    • Italiano A, Delcambre C, Hostein I et al (2010) Treatment with the mTOR inhibitor temsirolimus in patients with malignant PEComa. Ann Oncol 21:1135-1137
    • (2010) Ann Oncol , vol.21 , pp. 1135-1137
    • Italiano, A.1    Delcambre, C.2    Hostein, I.3
  • 137
    • 64049117132 scopus 로고    scopus 로고
    • Tumorigenic properties of alternative osteopontin isoforms in mesothelioma
    • Ivanov SV, Ivanova AV, Goparaju CM et al (2009) Tumorigenic properties of alternative osteopontin isoforms in mesothelioma. Biochem Biophys Res Commun 382:514-518
    • (2009) Biochem Biophys Res Commun , vol.382 , pp. 514-518
    • Ivanov, S.V.1    Ivanova, A.V.2    Goparaju, C.M.3
  • 138
    • 68249145205 scopus 로고    scopus 로고
    • Pathology of soft-tissue tumors: Daily diagnosis, molecular cytogenetics and experimental approach
    • Iwasaki H Nabeshima K Nishio J et al 2009 Pathology of soft-tissue tumors: daily diagnosis, molecular cytogenetics and experimental approachi Pathol Int 59: 501-521
    • (2009) Pathol Int , vol.59 , pp. 501-521
    • Iwasaki, H.1    Nabeshima, K.2    Nishio, J.3
  • 139
    • 0035796023 scopus 로고    scopus 로고
    • The contribution of endogenous sources of DNA damage to the multiple mutations in cancer
    • Jackson AL, Loeb LA (2001) The contribution of endogenous sources of DNA damage to the multiple mutations in cancer. Mutat Res 477:7-21
    • (2001) Mutat Res , vol.477 , pp. 7-21
    • Jackson, A.L.1    Loeb, L.A.2
  • 140
    • 79551590694 scopus 로고    scopus 로고
    • The semisynthetic flavonoid monoHER sensitises human soft tissue sarcoma cells to doxorubicin-induced apoptosis via inhibition of nuc lear factor-kappaB
    • Jacobs H, Bast A, Peters GJ et al (2011) The semisynthetic flavonoid monoHER sensitises human soft tissue sarcoma cells to doxorubicin-induced apoptosis via inhibition of nuc lear factor-kappaB. Br J Cancer 104:437-440
    • (2011) Br J Cancer , vol.104 , pp. 437-440
    • Jacobs, H.1    Bast, A.2    Peters, G.J.3
  • 141
    • 34547630697 scopus 로고    scopus 로고
    • The survival kinase Mirk/Dyrk1B is a downstream effector of oncogenic K-ras in pancreatic cancer
    • Jin K, Park S, Ewton DZ et al (2007) The survival kinase Mirk/Dyrk1B is a downstream effector of oncogenic K-ras in pancreatic cancer. Cancer Res 67:7247-7255
    • (2007) Cancer Res , vol.67 , pp. 7247-7255
    • Jin, K.1    Park, S.2    Ewton, D.Z.3
  • 142
    • 80053062871 scopus 로고    scopus 로고
    • Preliminary efficacy of the anti-insulin-like growth factor type 1 receptor antibody figitumumab in patients with refractory Ewing sarcoma
    • Juergens H, Daw NC, Geoerger B et al (2011) Preliminary efficacy of the anti-insulin-like growth factor type 1 receptor antibody figitumumab in patients with refractory Ewing sarcoma. J Clin Oncol 29:4534-4540
    • (2011) J Clin Oncol , vol.29 , pp. 4534-4540
    • Juergens, H.1    Daw, N.C.2    Geoerger, B.3
  • 143
    • 11144353897 scopus 로고    scopus 로고
    • Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor
    • Kalinichenko VV, Major ML, Wang X et al (2004) Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. Genes Dev 18:830-850
    • (2004) Genes Dev , vol.18 , pp. 830-850
    • Kalinichenko, V.V.1    Major, M.L.2    Wang, X.3
  • 144
    • 33846882630 scopus 로고    scopus 로고
    • Molecular pathogenesis of osteosarcoma
    • Kansara M, Thomas DM (2007) Molecular pathogenesis of osteosarcoma. DNA Cell Biol 26:1-18
    • (2007) DNA Cell Biol , vol.26 , pp. 1-18
    • Kansara, M.1    Thomas, D.M.2
  • 145
    • 84872104838 scopus 로고    scopus 로고
    • Progno stic factors in adolescents and young adults (AYA) with high risk soft tissue sarcoma (STS) treated by adjuvant chemotherapy: A study based on pooled European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62771 and 62931
    • Kasper B, Ouali M, van Glabbeke M et al (2013) Progno stic factors in adolescents and young adults (AYA) with high risk soft tissue sarcoma (STS) treated by adjuvant chemotherapy: a study based on pooled European Organisation for Research and Treatment of Cancer (EORTC) clinical trials 62771 and 62931. Eur J Cancer 49:449-456
    • (2013) Eur J Cancer , vol.49 , pp. 449-456
    • Kasper, B.1    Ouali, M.2    Van Glabbeke, M.3
  • 146
    • 33645748053 scopus 로고    scopus 로고
    • NF-kappaB is essential for the progression of KSHV-and EBV-infected lymphomas in vivo
    • Keller SA, Hernandez-Hopkins D, Vider J et al (2006) NF-kappaB is essential for the progression of KSHV-and EBV-infected lymphomas in vivo. Blood 107:3295-3302
    • (2006) Blood , vol.107 , pp. 3295-3302
    • Keller, S.A.1    Hernandez-Hopkins, D.2    Vider, J.3
  • 147
    • 0037301976 scopus 로고    scopus 로고
    • Low expression of p27 indicates a poor prognosis in patients with high-grade astrocytomas
    • Kirla RM, Haapasalo HK, Kalimo H et al (2003) Low expression of p27 indicates a poor prognosis in patients with high-grade astrocytomas. Cancer 97:644-648
    • (2003) Cancer , vol.97 , pp. 644-648
    • Kirla, R.M.1    Haapasalo, H.K.2    Kalimo, H.3
  • 148
    • 34547660321 scopus 로고    scopus 로고
    • A spatially and temporally restricted mouse model of soft tissue sarcoma
    • Kirsch DG, Dinulescu DM, Mille r JB et al (2007) A spatially and temporally restricted mouse model of soft tissue sarcoma. Nat Med 13:992-997
    • (2007) Nat Med , vol.13 , pp. 992-997
    • Kirsch, D.G.1    Dinulescu, D.M.2    Mille, R.J.B.3
  • 149
    • 13244264730 scopus 로고    scopus 로고
    • Endogenous angiogenin in endothelial cells is a general requirement for cell proliferation and angiogenesis
    • Kishimoto K, Liu S, Tsuji T et al (2005) Endogenous angiogenin in endothelial cells is a general requirement for cell proliferation and angiogenesis. Oncogene 24:445-456
    • (2005) Oncogene , vol.24 , pp. 445-456
    • Kishimoto, K.1    Liu, S.2    Tsuji, T.3
  • 150
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • Knudson AG Jr (1971) Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 68:820-823
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 820-823
    • Knudson Jr., A.G.1
  • 151
    • 28544447468 scopus 로고    scopus 로고
    • Suppression of urokinase receptor expression by thalidomide is associated with inhibition of nuclear factor kappaB activation and subsequently suppressed ovarian cancer dissemination
    • Kobayashi H, Yagyu T, Kondo T et al (2005) Suppression of urokinase receptor expression by thalidomide is associated with inhibition of nuclear factor kappaB activation and subsequently suppressed ovarian cancer dissemination. Cancer Res 65:10464-10471
    • (2005) Cancer Res , vol.65 , pp. 10464-10471
    • Kobayashi, H.1    Yagyu, T.2    Kondo, T.3
  • 152
    • 40549093336 scopus 로고    scopus 로고
    • Malignant tumors of blood vessels: Angiosarcomas, hemangioendotheliomas, and hemangioperictyomas
    • Koch M, Nielsen GP, Yoon SS (2008) Malignant tumors of blood vessels: angiosarcomas, hemangioendotheliomas, and hemangioperictyomas. J Surg Oncol 97:321-329
    • (2008) J Surg Oncol , vol.97 , pp. 321-329
    • Koch, M.1    Nielsen, G.P.2    Yoon, S.S.3
  • 153
    • 33846562011 scopus 로고    scopus 로고
    • Emmprin in epithelioid sarcoma: Expression in tumor cell membrane and stimulation of MMP-2 production in tumor-associated fibroblasts
    • Koga K, Nabeshima K, Aoki M et al (2007) Emmprin in epithelioid sarcoma: expression in tumor cell membrane and stimulation of MMP-2 production in tumor-associated fibroblasts. Int J Cancer 120:761-768
    • (2007) Int J Cancer , vol.120 , pp. 761-768
    • Koga, K.1    Nabeshima, K.2    Aoki, M.3
  • 154
    • 28244462756 scopus 로고    scopus 로고
    • Microvessel density and HIF-1alpha expression correlate with malignant potential in fibrohistiocytic tumors
    • Koga K, Nabeshima K, Nishimura N et al (2005) Microvessel density and HIF-1alpha expression correlate with malignant potential in fibrohistiocytic tumors. Eur J Dermatol 15:465-469
    • (2005) Eur J Dermatol , vol.15 , pp. 465-469
    • Koga, K.1    Nabeshima, K.2    Nishimura, N.3
  • 155
    • 50249102179 scopus 로고    scopus 로고
    • Alterations of RB1 gene in embryonal and alveolar rhabdomyosarcoma: Special reference to utility of pRB immunoreactivity in differential diagnosis of rhabdomyosarcoma subtype
    • Kohashi K, Oda Y, Yamamoto H et al (2008) Alterations of RB1 gene in embryonal and alveolar rhabdomyosarcoma: special reference to utility of pRB immunoreactivity in differential diagnosis of rhabdomyosarcoma subtype. J Cance r Res Clin Oncol 134:1097-1103
    • (2008) J Cance R Res Clin Oncol , vol.134 , pp. 1097-1103
    • Kohashi, K.1    Oda, Y.2    Yamamoto, H.3
  • 156
    • 15244344206 scopus 로고    scopus 로고
    • HIF-1α induces genetic instability by transcriptionally downregulating MutSalpha expression
    • Koshiji M, To KK, Hammer S et al (2005) HIF-1α induces genetic instability by transcriptionally downregulating MutSalpha expression. Mol Cell 17:793-803
    • (2005) Mol Cell , vol.17 , pp. 793-803
    • Koshiji, M.1    To, K.K.2    Hammer, S.3
  • 157
    • 79951798883 scopus 로고    scopus 로고
    • Metastasis: New perspectives on an old problem
    • doi:10.1186/1476-4598-10-22
    • Kraljevic Pavelic S, Sedic M, Bosnjak H et al (2011) Metastasis: new perspectives on an old problem. Mol Cancer 10:22. doi:10.1186/1476-4598-10-22
    • (2011) Mol Cancer , vol.10 , pp. 22
    • Kraljevic Pavelic, S.1    Sedic, M.2    Bosnjak, H.3
  • 158
    • 0033795924 scopus 로고    scopus 로고
    • Beta-catenin in soft tissue sarcomas: Expression is related to proliferative activity in high-grade sarcomas
    • Kuhnen C, Herter P, Muller O et a l (2000) Beta-catenin in soft tissue sarcomas: expression is related to proliferative activity in high-grade sarcomas. Mod Pathol 13:1005-1013
    • (2000) Mod Pathol , vol.13 , pp. 1005-1013
    • Kuhnen, C.1    Herter, P.2    Muller, O.3
  • 159
    • 80054083352 scopus 로고    scopus 로고
    • An eval uation of cediranib as new agent for alveolar soft part sarcoma (ASPS
    • Kummar S, Strassberger A, Monks A et al (2011) An eval uation of cediranib as new agent for alveolar soft part sarcoma (ASPS). J Clin Oncol 29:10001. http://meeting.ascopubs.org/cgi/content/abstract/29/15-suppl/10001? sid=629fd0d8-f8f1-4905-816e-134f8d1ad715
    • (2011) J Clin Oncol , vol.29 , pp. 10001
    • Kummar, S.1    Strassberger, A.2    Monks, A.3
  • 160
    • 47849098044 scopus 로고    scopus 로고
    • Inflammation: Gearing the journey to cancer
    • Kundu JK, S urh YJ (2008) Inflammation: gearing the journey to cancer. Mutat Res 659:15-30
    • (2008) Mutat Res , vol.659 , pp. 15-30
    • Kundu, J.K.1    Surh, Y.J.2
  • 161
    • 84859635458 scopus 로고    scopus 로고
    • Emerging avenues linking inflammation and cancer
    • Kundu JK, Surh YJ (2012) Emerging avenues linking inflammation and cancer. Free Radic Biol Med 52:2013-2037
    • (2012) Free Radic Biol Med , vol.52 , pp. 2013-2037
    • Kundu, J.K.1    Surh, Y.J.2
  • 162
    • 0034535302 scopus 로고    scopus 로고
    • Vascular endothelium growth fac tor and angiogenin in the serum of patients with osteosarcoma and Ewing's tumor
    • Kushlinskii NE, Babkina IV, Solov'ev YN et al (2000) Vascular endothelium growth fac tor and angiogenin in the serum of patients with osteosarcoma and Ewing's tumor. Bull Exp Biol Med 130:691-693
    • (2000) Bull Exp Biol Med , vol.130 , pp. 691-693
    • Kushlinskii, N.E.1    Babkina, I.V.2    Solov'Ev, Y.N.3
  • 163
    • 0027508958 scopus 로고
    • MDM2 gene amplification in metastatic osteosarcoma
    • Ladanyi M, Cha C, Lewis R et al (1993) MDM2 gene amplification in metastatic osteosarcoma. Cancer Res 53:16-18
    • (1993) Cancer Res , vol.53 , pp. 16-18
    • Ladanyi, M.1    Cha, C.2    Lewis, R.3
  • 164
    • 20444422917 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) is frequently expressed in multiple myeloma and is an independent predictor of poor outcome
    • Ladetto M, Vallet S, Trojan A et al (2005) Cyclooxygenase-2 (COX-2) is frequently expressed in multiple myeloma and is an independent predictor of poor outcome. Blood 105:4784-4791
    • (2005) Blood , vol.105 , pp. 4784-4791
    • Ladetto, M.1    Vallet, S.2    Trojan, A.3
  • 165
    • 44349145029 scopus 로고    scopus 로고
    • Sarcoma epidemiology and etiology: Potential environmental and genetic factors
    • Lahat G, Lazar A, Lev D (2008) Sarcoma epidemiology and etiology: potential environmental and genetic factors. Surg Clin North Am 88:451-481
    • (2008) Surg Clin North Am , vol.88 , pp. 451-481
    • Lahat, G.1    Lazar, A.2    Lev, D.3
  • 166
    • 80053312080 scopus 로고    scopus 로고
    • The expression of c-Met pathway components in unclassified pleomorphic sarcoma/malignant fibrous histiocytoma (UPS/MFH): A tissue microarray study
    • Lahat G, Zhang P, Zhu QS et al (2011) The expression of c-Met pathway components in unclassified pleomorphic sarcoma/malignant fibrous histiocytoma (UPS/MFH): a tissue microarray study. Histopathology 59:556-561
    • (2011) Histopathology , vol.59 , pp. 556-561
    • Lahat, G.1    Zhang, P.2    Zhu, Q.S.3
  • 167
    • 54249104991 scopus 로고    scopus 로고
    • Autophagy: A novel mechanism of synergistic cytotoxicity between doxorubicin and roscovitine in a sarcoma model
    • Lambert LA, Qiao N, Hunt KK et al (2008) Autophagy: a novel mechanism of synergistic cytotoxicity between doxorubicin and roscovitine in a sarcoma model. Cancer Res 68:7966-7974
    • (2008) Cancer Res , vol.68 , pp. 7966-7974
    • Lambert, L.A.1    Qiao, N.2    Hunt, K.K.3
  • 168
    • 34249905448 scopus 로고    scopus 로고
    • Effects of RAS on the genesis of embryonal rhabdomyosarcoma
    • Langenau DM, Keefe MD, Storer NY et al (2007) Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Genes Dev 21:1382-1395
    • (2007) Genes Dev , vol.21 , pp. 1382-1395
    • Langenau, D.M.1    Keefe, M.D.2    Storer, N.Y.3
  • 169
    • 13944274222 scopus 로고    scopus 로고
    • FoxM1 is required for execution of the mitotic programme and chromosome stability
    • Laoukili J, Kooistra MR, Bras A et al (2005) FoxM1 is required for execution of the mitotic programme and chromosome stability. Nat Cell Biol 7:126-136
    • (2005) Nat Cell Biol , vol.7 , pp. 126-136
    • Laoukili, J.1    Kooistra, M.R.2    Bras, A.3
  • 170
    • 0035853166 scopus 로고    scopus 로고
    • Inherited susceptibility to uterine leiomyomas and renal cell cancer
    • Launonen V, Vierimaa O, Kiuru M et al (2001) Inherited susceptibility to uterine leiomyomas and renal cell cancer. Proc Natl Acad Sci USA 98:3387-3392
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3387-3392
    • Launonen, V.1    Vierimaa, O.2    Kiuru, M.3
  • 171
    • 37549023043 scopus 로고    scopus 로고
    • Angiogenesis-promoting gene patterns in alveolar soft part sarcoma
    • Lazar AJ, Das P, Tuvin D et al (2007) Angiogenesis-promoting gene patterns in alveolar soft part sarcoma. Clin Cancer Res 13:7314-7321
    • (2007) Clin Cancer Res , vol.13 , pp. 7314-7321
    • Lazar, A.J.1    Das, P.2    Tuvin, D.3
  • 172
    • 77957341199 scopus 로고    scopus 로고
    • Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: An open-label multicentre randomised phase 3 trial
    • Le Cesne A, Ray-Coquard I, Bui BN et al (2010) Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: an open-label multicentre randomised phase 3 trial. Lancet Oncol 11:942-949
    • (2010) Lancet Oncol , vol.11 , pp. 942-949
    • Le Cesne, A.1    Ray-Coquard, I.2    Bui, B.N.3
  • 173
    • 0027232042 scopus 로고
    • P53 Mutation and MDM2 amplification in human soft tissue sarcomas
    • Lea ch FS, Tokino T, Meltzer P et al (1993) p53 Mutation and MDM2 amplification in human soft tissue sarcomas. Cancer Res 53:2231-2234
    • (1993) Cancer Res , vol.53 , pp. 2231-2234
    • Lea Ch, F.S.1    Tokino, T.2    Meltzer, P.3
  • 174
    • 77957875746 scopus 로고    scopus 로고
    • Paeonol oxime inhibits bFGF-induced angiogenesis and reduces VEGF levels in fibrosarcoma cells
    • Lee HJ, Kim SA, Lee HJ et al (2010) Paeonol oxime inhibits bFGF-induced angiogenesis and reduces VEGF levels in fibrosarcoma cells. PLoS ONE 5:e12358
    • (2010) PLoS ONE , vol.5
    • Lee, H.J.1    Kim, S.A.2    Lee, H.J.3
  • 175
    • 84858158912 scopus 로고    scopus 로고
    • Blockade of VEGF-A suppresses tumor growth via inhibition of autocrine signaling through FAK and AKT
    • Lee J, Ku T, Yu H et al (2012) Blockade of VEGF-A suppresses tumor growth via inhibition of autocrine signaling through FAK and AKT. Cancer Lett 318:221-225
    • (2012) Cancer Lett , vol.318 , pp. 221-225
    • Lee, J.1    Ku, T.2    Yu, H.3
  • 176
    • 79960840344 scopus 로고    scopus 로고
    • Differential dependency of human cancer cells on vascular endothelial growth factor-mediated autocrine growth and survival
    • Lee J, Lee J, Yu H et al (2011) Differential dependency of human cancer cells on vascular endothelial growth factor-mediated autocrine growth and survival. Cancer Lett 309:145-150
    • (2011) Cancer Lett , vol.309 , pp. 145-150
    • Lee, J.1    Lee, J.2    Yu, H.3
  • 177
    • 0024592142 scopus 로고
    • Constitutive and PMA-induced interleukin-1 production by the human astrocytoma cell line T24
    • Lee JC, Simon PL, Young PR (1989) Constitutive and PMA-induced interleukin-1 production by the human astrocytoma cell line T24. Cell Immunol 118:298-311
    • (1989) Cell Immunol , vol.118 , pp. 298-311
    • Lee, J.C.1    Simon, P.L.2    Young, P.R.3
  • 178
    • 18744373874 scopus 로고    scopus 로고
    • Downregulation of Skp2 and p27/Kip1 synergistically induces apoptosis in T98G glioblastoma cells
    • Lee SH, McCormick F (2005) Downregulation of Skp2 and p27/Kip1 synergistically induces apoptosis in T98G glioblastoma cells. J Mol Med (Berl) 83:296-307
    • (2005) J Mol Med (Berl , vol.83 , pp. 296-307
    • Lee, S.H.1    McCormick, F.2
  • 179
    • 33745234207 scopus 로고    scopus 로고
    • Increased risk of cancer in patients with fumarate hydratase germline mutation
    • Lehtonen HJ, Kiuru M, Ylisaukko-oja SK et al (2006) Increased risk of cancer in patients with fumarate hydratase germline mutation. J Med Genet 43:523-526
    • (2006) J Med Genet , vol.43 , pp. 523-526
    • Lehtonen, H.J.1    Kiuru, M.2    Ylisaukko-Oja, S.K.3
  • 180
    • 27344455930 scopus 로고    scopus 로고
    • Recrudescent Kaposi's sarcoma after initiation of HAART: A manifestation of immune reconstitution syndrome
    • Leidner RS, Aboulafia DM (2005) Recrudescent Kaposi's sarcoma after initiation of HAART: a manifestation of immune reconstitution syndrome. AIDS Patient Care STDS 19:635-644
    • (2005) AIDS Patient Care STDS , vol.19 , pp. 635-644
    • Leidner, R.S.1    Aboulafia, D.M.2
  • 181
    • 0034029126 scopus 로고    scopus 로고
    • Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling
    • Lemay S Davidson D Latour S et al 2000 Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling Mol Cell Biol 20: 2743-2754
    • (2000) Mol Cell Biol , vol.20 , pp. 2743-2754
    • Lemay, S.1    Davidson, D.2    Latour, S.3
  • 182
    • 33845212729 scopus 로고    scopus 로고
    • Interleukin-1 and cancer progression: The emerging role of interleukin-1
    • doi:10.1186/1479-5876-4-48
    • Lewis AM, Varghese S, Xu H et al (2006) Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment. J Transl Med 4:48. doi:10.1186/1479-5876- 4-48
    • (2006) J Transl Med , vol.4 , pp. 48
    • Lewis, A.M.1    Varghese, S.2    Xu, H.3
  • 183
    • 0037443760 scopus 로고    scopus 로고
    • IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis
    • Li A, Dubey S, Varney ML et al (2003) IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J Immunol 170:3369-3376
    • (2003) J Immunol , vol.170 , pp. 3369-3376
    • Li, A.1    Dubey, S.2    Varney, M.L.3
  • 184
    • 0014587529 scopus 로고
    • Soft-tissue sarcomas, breast cancer, and other neoplasms A familial syndrome?
    • Li FP, Fraumeni JF Jr (1969) Soft-tissue sarcomas, breast cancer, and other neoplasms. A familial syndrome? Ann Intern Med 71:747-752
    • (1969) Ann Intern Med , vol.71 , pp. 747-752
    • Li, F.P.1    Fraumeni Jr., J.F.2
  • 185
    • 79959770652 scopus 로고    scopus 로고
    • Efficient virotherapy for osteosarcoma by telomerasespecific oncolytic adenovirus
    • Li G, Kawashima H, Ogose A et al (2011) Efficient virotherapy for osteosarcoma by telomerasespecific oncolytic adenovirus. J Cancer Res Clin Oncol 137:1037-1051
    • (2011) J Cancer Res Clin Oncol , vol.137 , pp. 1037-1051
    • Li, G.1    Kawashima, H.2    Ogose, A.3
  • 186
    • 84861910687 scopus 로고    scopus 로고
    • Curcumin inhibits proliferation and invasion of osteosarcoma cells through inactivation of Notch-1 signaling
    • Li Y, Zhang J, Ma D et al (2012) Curcumin inhibits proliferation and invasion of osteosarcoma cells through inactivation of Notch-1 signaling. FEBS J 279:2247-2259
    • (2012) FEBS J , vol.279 , pp. 2247-2259
    • Li, Y.1    Zhang, J.2    Ma, D.3
  • 187
    • 34248141100 scopus 로고    scopus 로고
    • A cytokine-mediated link between innate immunity, inflammation, and cancer
    • Lin WW, Karin M (2007) A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117:1175-1183
    • (2007) J Clin Invest , vol.117 , pp. 1175-1183
    • Lin, W.W.1    Karin, M.2
  • 188
    • 0035129306 scopus 로고    scopus 로고
    • Osteogenic sarcoma associated with Diamond-Blackfan anemia: A report from the Diamond-Blackfan Anemia Registry
    • Lipton JM, Federman N, Khabbaze Y et al (2001) Osteogenic sarcoma associated with Diamond-Blackfan anemia: a report from the Diamond-Blackfan Anemia Registry. J Pediatr Hematol Oncol 23:39-44
    • (2001) J Pediatr Hematol Oncol , vol.23 , pp. 39-44
    • Lipton, J.M.1    Federman, N.2    Khabbaze, Y.3
  • 189
    • 84861454453 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors induce anoikis in osteosarcoma via PI3K/Akt pathway
    • Liu B, Qu L, Yang Z et al (2012a) Cyclooxygenase-2 inhibitors induce anoikis in osteosarcoma via PI3K/Akt pathway. Med Hypotheses 79:98-100
    • (2012) Med Hypotheses , vol.79 , pp. 98-100
    • Liu, B.1    Qu, L.2    Yang, Z.3
  • 190
    • 84865637125 scopus 로고    scopus 로고
    • Induction of histiocytic sarcoma in mouse skeletal muscle
    • Liu J, Hettmer S, Milsom MD et al (2012b) Induction of histiocytic sarcoma in mouse skeletal muscle. PLoS ONE 7:e44044
    • (2012) PLoS ONE , vol.7
    • Liu, J.1    Hettmer, S.2    Milsom, M.D.3
  • 191
    • 33645734725 scopus 로고    scopus 로고
    • FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells
    • Liu M, Dai B, Kang SH et al (2006) FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells. Cancer Res 66:3593-3602
    • (2006) Cancer Res , vol.66 , pp. 3593-3602
    • Liu, M.1    Dai, B.2    Kang, S.H.3
  • 192
    • 43549085520 scopus 로고    scopus 로고
    • The inhibition of in vivo tumorigenesis of osteosarcoma (OS)-732 cells by antisense human osteopontin RNA
    • Liu SJ, Zhang DQ, Sui XM et al (2008) The inhibition of in vivo tumorigenesis of osteosarcoma (OS)-732 cells by antisense human osteopontin RNA. Cell Mol Biol Lett 13:11-19
    • (2008) Cell Mol Biol Lett , vol.13 , pp. 11-19
    • Liu, S.J.1    Zhang, D.Q.2    Sui, X.M.3
  • 193
    • 73449111266 scopus 로고    scopus 로고
    • Developing c-MET pathway inhibitors for cancer therapy: Progress and challenges
    • Liu X, Newton RC, Scherle PA (2010) Developing c-MET pathway inhibitors for cancer therapy: progress and challenges. Trends Mol Med 16:37-45
    • (2010) Trends Mol Med , vol.16 , pp. 37-45
    • Liu, X.1    Newton, R.C.2    Scherle, P.A.3
  • 195
    • 0141994730 scopus 로고    scopus 로고
    • Src family protein-tyrosine kinases alter the function of PTEN to regu late phosphatidylinositol 3-kinase/AKT cascades
    • Lu Y, Yu Q, Liu JH et al (2003) Src family protein-tyrosine kinases alter the function of PTEN to regu late phosphatidylinositol 3-kinase/AKT cascades. J Biol Chem 278:40057-40066
    • (2003) J Biol Chem , vol.278 , pp. 40057-40066
    • Lu, Y.1    Yu, Q.2    Liu, J.H.3
  • 196
    • 84860512314 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor flavopiridol potentiates doxorubicin efficacy in advanced sarcomas: Preclinical investigations and results of a phase i dose-escalation clinical trial
    • Luke JJ, D'Adamo DR, Dickson MA et al (2012) The cyclin-dependent kinase inhibitor flavopiridol potentiates doxorubicin efficacy in advanced sarcomas: preclinical investigations and results of a phase I dose-escalation clinical trial. Clin Cancer Res 18:2638-2647
    • (2012) Clin Cancer Res , vol.18 , pp. 2638-2647
    • Luke, J.J.1    D'Adamo, D.R.2    Dickson, M.A.3
  • 198
    • 84864858481 scopus 로고    scopus 로고
    • In vitro effects of the tyrosine kinase inhibitor, masitinib mesylate, on canine hemangiosarcoma cell lines
    • Lyles SE, Milner RJ, Kow K et al (2012) In vitro effects of the tyrosine kinase inhibitor, masitinib mesylate, on canine hemangiosarcoma cell lines. Vet Comp Oncol 10:223-235
    • (2012) Vet Comp Oncol , vol.10 , pp. 223-235
    • Lyles, S.E.1    Milner, R.J.2    Kow, K.3
  • 199
    • 66649121354 scopus 로고    scopus 로고
    • Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma
    • Ma Q, Cavallin LE, Yan B et al (2009) Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcoma. Proc Natl Acad Sci USA 106:8683-8688
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 8683-8688
    • Ma, Q.1    Cavallin, L.E.2    Yan, B.3
  • 200
    • 0035174752 scopus 로고    scopus 로고
    • Familial gastrointestinal stromal tumor with hyperpigmentation: Association with a germline mutation of the c-kit gene
    • Maeyama H, Hidaka E, Ota H et al (2001) Familial gastrointestinal stromal tumor with hyperpigmentation: association with a germline mutation of the c-kit gene. Gastroenterology 120:210-215
    • (2001) Gastroenterology , vol.120 , pp. 210-215
    • Maeyama, H.1    Hidaka, E.2    Ota, H.3
  • 201
    • 67650293850 scopus 로고    scopus 로고
    • Phase II study of sorafenib in patients with metastatic or recurrent sarcomas
    • Maki RG, D'Adamo DR, Keohan ML et al (2009) Phase II study of sorafenib in patients with metastatic or recurrent sarcomas. J Clin Oncol 27:3133-3140
    • (2009) J Clin Oncol , vol.27 , pp. 3133-3140
    • Maki, R.G.1    D'Adamo, D.R.2    Keohan, M.L.3
  • 202
    • 34447572873 scopus 로고    scopus 로고
    • Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: Results of sarcoma alliance for research through collaboration study 002 (corrected
    • Maki RG Wathen JK Patel SR et al 2007 Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: results of sarcoma alliance for research through collaboration study 002 (corrected J Clin Oncol 25 2755-2763
    • (2007) J Clin Oncol , vol.25 , pp. 2755-2763
    • Maki, R.G.1    Wathen, J.K.2    Patel, S.R.3
  • 203
    • 84862907964 scopus 로고    scopus 로고
    • Phase I/II trial and pharmacokinetic study of cixutumumab in pediatric patients with refractory solid tumors and Ewing sarcoma: A report from the Children's Oncology Group
    • Malempati S, Weigel B, Ingle AM et al (2012) Phase I/II trial and pharmacokinetic study of cixutumumab in pediatric patients with refractory solid tumors and Ewing sarcoma: a report from the Children's Oncology Group. J Clin Oncol 30:256-262
    • (2012) J Clin Oncol , vol.30 , pp. 256-262
    • Malempati, S.1    Weigel, B.2    Ingle, A.M.3
  • 204
    • 0025633582 scopus 로고
    • Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
    • Malkin D, Li FP, Strong LC et al (1990) Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 250:1233-1238
    • (1990) Science , vol.250 , pp. 1233-1238
    • Malkin, D.1    Li, F.P.2    Strong, L.C.3
  • 205
    • 16544378834 scopus 로고    scopus 로고
    • Implications for oxidative and nitrative stress in the pathogenesis of AIDS-related Kaposi's sarcoma
    • Mallery SR, Pei P, Landwehr DJ et al (2004) Implications for oxidative and nitrative stress in the pathogenesis of AIDS-related Kaposi's sarcoma. Carcinogenesis 25:597-603
    • (2004) Carcinogenesis , vol.25 , pp. 597-603
    • Mallery, S.R.1    Pei, P.2    Landwehr, D.J.3
  • 206
    • 47949096781 scopus 로고    scopus 로고
    • Cancer-related inflammation
    • Mantovani A, Allavena P, Sica A et al (2008) Cancer-related inflammation. Nature 454:436-444
    • (2008) Nature , vol.454 , pp. 436-444
    • Mantovani, A.1    Allavena, P.2    Sica, A.3
  • 207
    • 66449129841 scopus 로고    scopus 로고
    • MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma
    • Marampon F, Bossi G, Ciccarelli C et al (2009) MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma. Mol Cancer Ther 8:543-551
    • (2009) Mol Cancer Ther , vol.8 , pp. 543-551
    • Marampon, F.1    Bossi, G.2    Ciccarelli, C.3
  • 208
    • 58049202910 scopus 로고    scopus 로고
    • Risk of second malignancies in survivors of retinoblastoma: More than 40 years of follow-up
    • Marees T, Moll AC, Imhof SM et al (2008) Risk of second malignancies in survivors of retinoblastoma: more than 40 years of follow-up. J Natl Cancer Inst 100:1771-1779
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1771-1779
    • Marees, T.1    Moll, A.C.2    Imhof, S.M.3
  • 209
    • 84864529527 scopus 로고    scopus 로고
    • Targeted therapies in sarcomas: Challenging the challenge
    • doi:10.1155/2012/626094
    • Martin Liberal J, Lagares-Tena L, Sainz-Jaspeado M et al (2012) Targeted therapies in sarcomas: challenging the challenge. Sarcoma 2012:626094. doi:10.1155/2012/626094
    • (2012) Sarcoma , vol.2012 , pp. 626094
    • Martin Liberal, J.1    Lagares-Tena, L.2    Sainz-Jaspeado, M.3
  • 210
    • 70349310228 scopus 로고    scopus 로고
    • RAS signaling dysregulation in human embryonal Rhabdomyosarcoma
    • Martinelli S, McDowell HP, Vigne SD et al (2009) RAS signaling dysregulation in human embryonal Rhabdomyosarcoma. Genes Chromosom Cancer 48:975-982
    • (2009) Genes Chromosom Cancer , vol.48 , pp. 975-982
    • Martinelli, S.1    McDowell, H.P.2    Vigne, S.D.3
  • 211
    • 77956254269 scopus 로고    scopus 로고
    • Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma
    • Mashima R, Honda K, Yang Y et al (2010) Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma. Lab Invest 90:1357-1364
    • (2010) Lab Invest , vol.90 , pp. 1357-1364
    • Mashima, R.1    Honda, K.2    Yang, Y.3
  • 212
    • 0027230568 scopus 로고
    • Ewing sarcoma 11; 22 translocation pr oduces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation
    • May WA, Gishizky ML, Lessnick SL et al (1993) Ewing sarcoma 11; 22 translocation pr oduces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation. Proc Natl Acad Sci USA 90:5752-5756
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5752-5756
    • May, W.A.1    Gishizky, M.L.2    Lessnick, S.L.3
  • 213
    • 84867404688 scopus 로고    scopus 로고
    • A phase II tri al of thalidomide in patients with refractory uterine carcinosarcoma and correlation with biomarkers of angiogenesis: A Gynecologic Oncology Group study
    • McMeekin DS, Sill MW, Darcy KM et al (2012) A phase II tri al of thalidomide in patients with refractory uterine carcinosarcoma and correlation with biomarkers of angiogenesis: a Gynecologic Oncology Group study. Gynecol Oncol 127:356-361
    • (2012) Gynecol Oncol , vol.127 , pp. 356-361
    • McMeekin, D.S.1    Sill, M.W.2    Darcy, K.M.3
  • 214
    • 0027489713 scopus 로고
    • Cytokines in inflammatory malignant fibrous histiocytoma presenting with leukemoid reaction
    • Melhem MF, Meisler AI, Saito R et al (1993) Cytokines in inflammatory malignant fibrous histiocytoma presenting with leukemoid reaction. Blood 82:2038-2044
    • (1993) Blood , vol.82 , pp. 2038-2044
    • Melhem, M.F.1    Meisler, A.I.2    Saito, R.3
  • 216
    • 33646265602 scopus 로고    scopus 로고
    • Mirk/Dyrk1b mediates cell survival in rhabdomyosarcomas
    • Mercer SE, Ewton DZ, Shah S et al (2006) Mirk/Dyrk1b mediates cell survival in rhabdomyosarcomas. Cancer Res 66:5143-5150
    • (2006) Cancer Res , vol.66 , pp. 5143-5150
    • Mercer, S.E.1    Ewton, D.Z.2    Shah, S.3
  • 217
    • 77957121811 scopus 로고    scopus 로고
    • Kaposi's sarcoma and its associated herpesvirus
    • Mesri EA, Cesarman E, Boshoff C (2010) Kaposi's sarcoma and its associated herpesvirus. Nat Rev Cancer 10:707-719
    • (2010) Nat Rev Cancer , vol.10 , pp. 707-719
    • Mesri, E.A.1    Cesarman, E.2    Boshoff, C.3
  • 218
    • 77949898532 scopus 로고    scopus 로고
    • Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors: A meta-analysis of 1,640 patients
    • Meta-analysis
    • Meta-analysis (2010) Comparison of two doses of imatinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors: a meta-analysis of 1,640 patients. J Clin Oncol 28:1247-1253
    • (2010) J Clin Oncol , vol.28 , pp. 1247-1253
  • 219
    • 80052696673 scopus 로고    scopus 로고
    • Mesna, doxorubicin, ifosfamide and dacarbazine chemotherapy for uterine leiomyosarcoma: A report of two cases
    • Minobe S, Todo Y, Suzuki Y et al (2011) Mesna, doxorubicin, ifosfamide and dacarbazine chemotherapy for uterine leiomyosarcoma: a report of two cases. J Obstet Gynaecol Res 37:645-649
    • (2011) J Obstet Gynaecol Res , vol.37 , pp. 645-649
    • Minobe, S.1    Todo, Y.2    Suzuki, Y.3
  • 220
    • 63449118087 scopus 로고    scopus 로고
    • Osteosarcoma incidence and survival rates from 1973 to 2004: Data from the Surveillance
    • Epidemiology, and End Results Program
    • Mirabello L, Troisi RJ, Sava ge SA (2009) Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program. Cancer 115:1531-1543
    • (2009) Cancer , vol.115 , pp. 1531-1543
    • Mirabello, L.1    Troisi, R.J.2    Sava Ge, S.A.3
  • 221
    • 84875633556 scopus 로고    scopus 로고
    • Phase I/IIa trial of the mammalian target of rapamycin inhibitor ridaforolimus (AP23573; MK-8669) administered orally in patients with refractory or advanced malignancies and sarcoma
    • Mita MM, Poplin E, Britten CD et al (201 3) Phase I/IIa trial of the mammalian target of rapamycin inhibitor ridaforolimus (AP23573; MK-8669) administered orally in patients with refractory or advanced malignancies and sarcoma. Ann Oncol 24:1104-1111
    • (2013) Ann Oncol , vol.24 , pp. 1104-1111
    • Mita, M.M.1    Poplin, E.2    Britten, C.D.3
  • 222
    • 77954155576 scopus 로고    scopus 로고
    • Hsp90 phosphorylation,Wee1 and the cell cycle
    • Mollapou r M, Tsutsumi S, Neckers L (2010) Hsp90 phosphorylation, Wee1 and the cell cycle. Cell Cycle 9:2310-2316
    • (2010) Cell Cycle , vol.9 , pp. 2310-2316
    • Mollapou, R.M.1    Tsutsumi, S.2    Neckers, L.3
  • 223
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand J, Zambetti GP, Olson DC et al (1992) The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69:1237-1245
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3
  • 224
    • 38449111748 scopus 로고    scopus 로고
    • Receptor activator of nuclear factor-kappaB ligand (RANKL) directly modu lates the gene expression profile of RANK-positive Saos-2 human osteosarcoma cells
    • Mori K, Berreur M, Blanchard F et al (2007) Receptor activator of nuclear factor-kappaB ligand (RANKL) directly modu lates the gene expression profile of RANK-positive Saos-2 human osteosarcoma cells. Oncol Rep 18:1365-1371
    • (2007) Oncol Rep , vol.18 , pp. 1365-1371
    • Mori, K.1    Berreur, M.2    Blanchard, F.3
  • 225
    • 0027943685 scopus 로고
    • Nuclear translocation of angiogenic proteins in endothelial cells: An essential step in angiogenesis
    • Moroianu J, Riordan JF (1994) Nuclear translocation of angiogenic proteins in endothelial cells: an essential step in angiogenesis. Biochemistry 33:12535-12539
    • (1994) Biochemistry , vol.33 , pp. 12535-12539
    • Moroianu, J.1    Riordan, J.F.2
  • 226
    • 55749095542 scopus 로고    scopus 로고
    • The clinical characteristics of Werner syndrome: Molecular and biochemical diagnosis
    • Muftuoglu M, Oshima J, von Kobbe C et al (2008) The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis. Hum Genet 124:369-377
    • (2008) Hum Genet , vol.124 , pp. 369-377
    • Muftuoglu, M.1    Oshima, J.2    Von Kobbe, C.3
  • 227
    • 84863601838 scopus 로고    scopus 로고
    • Chronic inflammation in cancer development
    • doi:10.3389/fimmu.2011.00098
    • Multhoff G, Molls M, Radons J (2012) Chronic inflammation in cancer development. Front Immunol 2:98. doi:10.3389/fimmu.2011.00098
    • (2012) Front Immunol , vol.2 , pp. 98
    • Multhoff, G.1    Molls, M.2    Radons, J.3
  • 228
    • 84875221247 scopus 로고    scopus 로고
    • Radiation, inflammation, and immune responses in cancer
    • doi:10.3389/fonc.2012.00058
    • Multhoff G, Radons J (2012) Radiation, inflammation, and immune responses in cancer. Front Oncol 2:58. doi:10.3389/fonc.2012.00058
    • (2012) Front Oncol , vol.2 , pp. 58
    • Multhoff, G.1    Radons, J.2
  • 229
    • 84868618609 scopus 로고    scopus 로고
    • Immunohistochemical analysis of the Akt/mTOR/4E-BP1 signalling pathway in canine haemangiomas and haemangiosarcomas
    • Murai A, Abou AS, Kodama A et al (2012a) Immunohistochemical analysis of the Akt/mTOR/4E-BP1 signalling pathway in canine haemangiomas and haemangiosarcomas. J Comp Pat hol 147:430-440
    • (2012) J Comp Pat Hol , vol.147 , pp. 430-440
    • Murai, A.1    Abou, A.S.2    Kodama, A.3
  • 230
    • 84864202400 scopus 로고    scopus 로고
    • Constitutive phosphorylation of the mTORC2/Akt/4EBP1 pathway in newly derived canine hemangiosarcoma cell lines
    • d oi:10.1186/1746-6148-8-128
    • Murai A, Asa SA, Kodama A et al (2012b) Constitutive phosphorylation of the mTORC2/Akt/4EBP1 pathway in newly derived canine hemangiosarcoma cell lines. BMC Vet Res 8:128. d oi:10.1186/1746-6148-8-128
    • (2012) BMC Vet Res , vol.8 , pp. 128
    • Murai, A.1    Asa, S.A.2    Kodama, A.3
  • 231
    • 0029964163 scopus 로고    scopus 로고
    • Modulation of transforming growth factor-beta secretio n from malignant glioma cells by interleukin-1 beta
    • Naganuma H, Sasaki A, Satoh E et al (1996) Modulation of transforming growth factor-beta secretio n from malignant glioma cells by interleukin-1 beta. Neurol Med Chir (Tokyo) 36:145-150
    • (1996) Neurol Med Chir (Tokyo , vol.36 , pp. 145-150
    • Naganuma, H.1    Sasaki, A.2    Satoh, E.3
  • 232
    • 5144226211 scopus 로고    scopus 로고
    • PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
    • Nagata Y, Lan KH, Zhou X et al (2004) PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 6:117-127
    • (2004) Cancer Cell , vol.6 , pp. 117-127
    • Nagata, Y.1    Lan, K.H.2    Zhou, X.3
  • 233
    • 84860506226 scopus 로고    scopus 로고
    • Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor te msirolimus in patients with refractory Ewing's sarcoma family tumors
    • Naing A, LoRusso P, Fu S et al (2012) Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor te msirolimus in patients with refractory Ewing's sarcoma family tumors. Clin Cancer Res 18:2625-2631
    • (2012) Clin Cancer Res , vol.18 , pp. 2625-2631
    • Naing, A.1    Lorusso, P.2    Fu, S.3
  • 234
    • 77955296367 scopus 로고    scopus 로고
    • Nitric oxide synthases, cyclooxygenase-2, nitrotyrosine, and angiogenesis in chondrosarcoma and their relation to prognosis
    • Nakagawa SA, Lopes A, de Lopes CA et al (2010) Nitric oxide synthases, cyclooxygenase-2, nitrotyrosine, and angiogenesis in chondrosarcoma and their relation to prognosis. J Bone Joint Surg Am 92:1738-1746
    • (2010) J Bone Joint Surg Am , vol.92 , pp. 1738-1746
    • Nakagawa, S.A.1    Lopes, A.2    De Lopes, C.A.3
  • 235
    • 7044239633 scopus 로고    scopus 로고
    • Effect of TNF-alpha on human osteosarcoma cell line Saos2-T NF-alpha regulation of bone sialoprotein gene expression in Saos2 osteoblastlike cells
    • Nakayama Y, Kato N, Nakajima Y et al (2004) Effect of TNF-alpha on human osteosarcoma cell line Saos2-T NF-alpha regulation of bone sialoprotein gene expression in Saos2 osteoblastlike cells. Cell Biol Int 28:653-660
    • (2004) Cell Biol Int , vol.28 , pp. 653-660
    • Nakayama, Y.1    Kato, N.2    Nakajima, Y.3
  • 236
    • 0033638672 scopus 로고    scopus 로고
    • Autocrine transforming growth factor-beta gro wth pathway in murine osteosarcoma cell lines associated with inability to affect phosphorylation of retinoblastoma protein
    • Navid F, Letterio JJ, Yeung CL et al (2000) Autocrine transforming growth factor-beta gro wth pathway in murine osteosarcoma cell lines associated with inability to affect phosphorylation of retinoblastoma protein. Sarcoma 4:93-102
    • (2000) Sarcoma , vol.4 , pp. 93-102
    • Navid, F.1    Letterio, J.J.2    Yeung, C.L.3
  • 237
    • 34347407347 scopus 로고    scopus 로고
    • Dok-3 plays a nonredundant role in negative regulation of B-cell activation
    • Ng CH, Xu S, Lam KP (2007) Dok-3 plays a nonredundant role in negative regulation of B-cell activation. Blood 110:259-266
    • (2007) Blood , vol.110 , pp. 259-266
    • Ng, C.H.1    Xu, S.2    Lam, K.P.3
  • 238
    • 77952017371 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein beta is up-regulated in giant cell tumor of bone and regulates RANKL expression
    • Ng PK, Tsui SK, Lau CP et al (2010) CCAAT/enhancer binding protein beta is up-regulated in giant cell tumor of bone and regulates RANKL expression. J Cell Biochem 110:438-446
    • (2010) J Cell Biochem , vol.110 , pp. 438-446
    • Ng, P.K.1    Tsui, S.K.2    Lau, C.P.3
  • 239
    • 0030864083 scopus 로고    scopus 로고
    • Establishment and characterization of a new synovial sarcoma cell line, SN-SY-1: Special reference to bcl-2 protein and SYT-SSX1 hy brid transcripts
    • Noguchi SI, Ueki T, Kawauchi S et al (1997) Establishment and characterization of a new synovial sarcoma cell line, SN-SY-1: special reference to bcl-2 protein and SYT-SSX1 hy brid transcripts. Int J Cancer 72:995-1002
    • (1997) Int J Cancer , vol.72 , pp. 995-1002
    • Noguchi, S.I.1    Ueki, T.2    Kawauchi, S.3
  • 240
    • 0032963472 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell surv ival and induction of Bcl-2 expression
    • Nö r JE, Christensen J, Mooney DJ et al (1999) Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell surv ival and induction of Bcl-2 expression. Am J Pathol 154:375-384
    • (1999) Am J Pathol , vol.154 , pp. 375-384
    • Nö, R.J.E.1    Christensen, J.2    Mooney, D.J.3
  • 241
    • 67651100893 scopus 로고    scopus 로고
    • Tumor suppressor microRNAs are underrepresented in primary effusion lymphoma and Kaposi sarcoma
    • O'Hara AJ, Wang L, Dezube BJ et al (2009) Tumor suppressor microRNAs are underrepresented in primary effusion lymphoma and Kaposi sarcoma. Blood 113:5938-5941
    • (2009) Blood , vol.113 , pp. 5938-5941
    • O'Hara, A.J.1    Wang, L.2    Dezube, B.J.3
  • 242
    • 0037193834 scopus 로고    scopus 로고
    • Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: A randomised trial
    • O'Sullivan B, Davis AM, Turcotte R et al (2002) Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial. Lancet 359:2235-2241
    • (2002) Lancet , vol.359 , pp. 2235-2241
    • O'Sullivan, B.1    Davis, A.M.2    Turcotte, R.3
  • 243
    • 2442471534 scopus 로고    scopus 로고
    • Aberrations of p16INK4A, p14ARF and p15INK4B genes in pediatric solid tumors
    • Obana K, Yang HW, Piao HY et al (2003) Aberrations of p16INK4A, p14ARF and p15INK4B genes in pediatric solid tumors. Int J Oncol 23:1151-1157
    • (2003) Int J Oncol , vol.23 , pp. 1151-1157
    • Obana, K.1    Yang, H.W.2    Piao, H.Y.3
  • 244
    • 33745853157 scopus 로고    scopus 로고
    • 8-nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species: Formation, occurrence, and implications in inflammation and carcinogenesis
    • Ohshima H, Sawa T, Akaike T (2006) 8-nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species: formation, occurrence, and implications in inflammation and carcinogenesis. Antioxid Redox Signal 8:1033-1045
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1033-1045
    • Ohshima, H.1    Sawa, T.2    Akaike, T.3
  • 245
    • 0035794312 scopus 로고    scopus 로고
    • CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis
    • Oldenborg PA Gresham HD Lindberg FP 2001 CD47-signal regulatory protein alpha (SIRPalpha) regulates Fcgamma and complement receptor-mediated phagocytosis J Exp Med 193:855-862
    • (2001) J Exp Med , vol.193 , pp. 855-862
    • Oldenborg, P.A.1    Gresham, H.D.2    Lindberg, F.P.3
  • 246
    • 75249097799 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751, 871) in patients with sarcoma and Ewing's sarcoma: A phase 1 expansion cohort study
    • Olmos D, Pos tel-Vinay S, Molife LR et al (2010) Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study. Lancet Oncol 11:129-135
    • (2010) Lancet Oncol , vol.11 , pp. 129-135
    • Olmos, D.1    Pos Tel-Vinay, S.2    Molife, L.R.3
  • 247
    • 70350572180 scopus 로고    scopus 로고
    • FoxM1, a critical regulator of oxidative stress during oncogenesis
    • Park HJ, Carr JR, Wang Z et al (2009) FoxM1, a critical regulator of oxidative stress during oncogenesis. EMBO J 28:2908-2918
    • (2009) EMBO J , vol.28 , pp. 2908-2918
    • Park, H.J.1    Carr, J.R.2    Wang, Z.3
  • 248
    • 79961219491 scopus 로고    scopus 로고
    • Activity of temozolomide and bevacizumab in the treatment of locally advanced, recurrent, and metastatic hemangiopericytoma and malignant solitary fibrous tumor
    • Park MS, Patel SR, Ludwig JA et al (2011) Activity of temozolomide and bevacizumab in the treatment of locally advanced, recurrent, and metastatic hemangiopericytoma and malignant solitary fibrous tumor. Cancer 117:4939-4947
    • (2011) Cancer , vol.117 , pp. 4939-4947
    • Park, M.S.1    Patel, S.R.2    Ludwig, J.A.3
  • 249
    • 26444506232 scopus 로고    scopus 로고
    • Asbestos exposure, pleural mesothelioma, and serum osteopontin levels
    • Pass HI, Lott D, Lon ardo F et al (2005) Asbestos exposure, pleural mesothelioma, and serum osteopontin levels. N Engl J Med 353:1564-1573
    • (2005) N Engl J Med , vol.353 , pp. 1564-1573
    • Pass, H.I.1    Lott, D.2    Lon Ardo, F.3
  • 250
    • 84863577285 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associat ed herpesvirus latency-associated nuclear antigen interacts with multifunctional angiogenin to utilize its antiapoptotic functions
    • Paudel N, Sadagopan S, Chakraborty S et al (2012) Kaposi's sarcoma-associat ed herpesvirus latency-associated nuclear antigen interacts with multifunctional angiogenin to utilize its antiapoptotic functions. J Virol 86:5974-5991
    • (2012) J Virol , vol.86 , pp. 5974-5991
    • Paudel, N.1    Sadagopan, S.2    Chakraborty, S.3
  • 251
    • 72449133456 scopus 로고    scopus 로고
    • Sorafenib induc es growth inhibition and apoptosis in human synovial sarcoma cells via inhibiting the RAF/MEK/ERK signaling pathway
    • Peng CL, Guo W, Ji T et al (2009) Sorafenib induc es growth inhibition and apoptosis in human synovial sarcoma cells via inhibiting the RAF/MEK/ERK signaling pathway. Cancer Biol Ther 8:1729-1736
    • (2009) Cancer Biol Ther , vol.8 , pp. 1729-1736
    • Peng, C.L.1    Guo, W.2    Ji, T.3
  • 252
    • 49049089340 scopus 로고    scopus 로고
    • A sys tematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma
    • Pervaiz N, Colterjohn N, Farrokhyar F et al (2008) A sys tematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma. Cancer 113:573-581
    • (2008) Cancer , vol.113 , pp. 573-581
    • Pervaiz, N.1    Colterjohn, N.2    Farrokhyar, F.3
  • 253
    • 34248216623 scopus 로고    scopus 로고
    • Phosphopro tein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival
    • Petricoin EFI, Espina V, Araujo RP et al (2007) Phosphopro tein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival. Cancer Res 67:3431-3440
    • (2007) Cancer Res , vol.67 , pp. 3431-3440
    • Efi, P.1    Espina, V.2    Araujo, R.P.3
  • 254
    • 0036793736 scopus 로고    scopus 로고
    • Adjuvant epirubicin with or without ifosfamide for adult soft-tissue sarcoma
    • Petrioli R, Coratti A, Correale P et al (2002) Adjuvant epirubicin with or without ifosfamide for adult soft-tissue sarcoma. Am J Clin Oncol 25:468-473
    • (2002) Am J Clin Oncol , vol.25 , pp. 468-473
    • Petrioli, R.1    Coratti, A.2    Correale, P.3
  • 255
    • 11144280578 scopus 로고    scopus 로고
    • Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data
    • Pilarsky C, Wenzig M, Specht T et al (2004) Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data. Neoplasia 6:744-750
    • (2004) Neoplasia , vol.6 , pp. 744-750
    • Pilarsky, C.1    Wenzig, M.2    Specht, T.3
  • 256
    • 0030826131 scopus 로고    scopus 로고
    • P27/kip1 expression in human astrocytic gliomas
    • Piva R, Cavalla P, Bortolotto S et al (1997) p27/kip1 expression in human astrocytic gliomas. Neurosci Lett 234:127-130
    • (1997) Neurosci Lett , vol.234 , pp. 127-130
    • Piva, R.1    Cavalla, P.2    Bortolotto, S.3
  • 257
    • 56749184290 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor signalling in neoplasia
    • Pollak M (2008) Insulin and insulin-like growth factor signalling in neoplasia. Nat Rev Cancer 8:915-928
    • (2008) Nat Rev Cancer , vol.8 , pp. 915-928
    • Pollak, M.1
  • 258
    • 11144284227 scopus 로고    scopus 로고
    • Evidence of increased microvessel density and activation of the hypoxia pathway in tumours from the hereditary leiomyomatosis and renal cell cancer syndrome
    • Pollard P, Wortham N, Barclay E et al (2005a ) Evidence of increased microvessel density and activation of the hypoxia pathway in tumours from the hereditary leiomyomatosis and renal cell cancer syndrome. J Pathol 205:41-49
    • (2005) J Pathol , vol.205 , pp. 41-49
    • Pollard, P.1    Wortham, N.2    Barclay, E.3
  • 259
    • 26444570010 scopus 로고    scopus 로고
    • Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations
    • Pollard PJ, Briere JJ, Alam NA et al (2005b ) Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. Hum Mol Genet 14:2231-2239
    • (2005) Hum Mol Genet , vol.14 , pp. 2231-2239
    • Pollard, P.J.1    Briere, J.J.2    Alam, N.A.3
  • 260
    • 84857640771 scopus 로고    scopus 로고
    • Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma
    • Postel-Vinay S, Veron AS, Tirode F et al (2012) Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma. Nat Genet 44:323-327
    • (2012) Nat Genet , vol.44 , pp. 323-327
    • Postel-Vinay, S.1    Veron, A.S.2    Tirode, F.3
  • 261
    • 20844453394 scopus 로고    scopus 로고
    • Activation of Src kinase Lyn by the Kaposi sarcoma-associated herpesvirus K1 protein: Implications for lymphomagenesis
    • Prakash O, Swamy OR, Peng X et al (2005) Activation of Src kinase Lyn by the Kaposi sarcoma-associated herpesvirus K1 protein: implications for lymphomagenesis. Blood 105:3987-3994
    • (2005) Blood , vol.105 , pp. 3987-3994
    • Prakash, O.1    Swamy, O.R.2    Peng, X.3
  • 262
    • 3543026281 scopus 로고    scopus 로고
    • EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3
    • Prieur A, Tirode F, Cohen P et al (2004) EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3. Mol Cell Biol 24:7275-7283
    • (2004) Mol Cell Biol , vol.24 , pp. 7275-7283
    • Prieur, A.1    Tirode, F.2    Cohen, P.3
  • 263
    • 80455162327 scopus 로고    scopus 로고
    • Expression of FoxM1 is required for the proliferation of medulloblastoma cells and indicates worse survival of patients
    • Priller M, Poschl J, Abrao L et al (2011) Expression of FoxM1 is required for the proliferation of medulloblastoma cells and indicates worse survival of patients. Clin Cancer Res 17:6791-6801
    • (2011) Clin Cancer Res , vol.17 , pp. 6791-6801
    • Priller, M.1    Poschl, J.2    Abrao, L.3
  • 264
    • 84873250219 scopus 로고    scopus 로고
    • Systemic therapy in soft tissue sarcomas: Past, present and future
    • Purohit S, Bhise R, Appachu S et al (2011) Systemic therapy in soft tissue sarcomas: past, present and future. Indian J Surg Oncol 2:327-331
    • (2011) Indian J Surg Oncol , vol.2 , pp. 327-331
    • Purohit, S.1    Bhise, R.2    Appachu, S.3
  • 265
    • 79951816312 scopus 로고    scopus 로고
    • Combination mTOR and IGF-1R inhibitio n: Phase i trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors
    • Quek R, Wang Q, Morgan JA et al (2011) Combination mTOR and IGF-1R inhibitio n: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors. Clin Cancer Res 17:871-879
    • (2011) Clin Cancer Res , vol.17 , pp. 871-879
    • Quek, R.1    Wang, Q.2    Morgan, J.A.3
  • 266
    • 84862275926 scopus 로고    scopus 로고
    • The molecular biology of soft-tissue sarcomas and current trends in therapy
    • doi:10.1155/2012/849456
    • Quesada J Amato R 2012The molecular biology of soft-tissue sarcomas and current trends in therapy Sarcoma 2012:849456 doi:10.1155/2012/849456
    • (2012) Sarcoma , vol.2012 , pp. 849456
    • Quesada, J.1    Amato, R.2
  • 267
    • 33746674531 scopus 로고    scopus 로고
    • P38MAPK mediates IL-1-induced down-regulation of aggrecan gene expression in human chondrocytes
    • Radons J, Bosserhoff AK, Grassel S et al (2006a ) p38MAPK mediates IL-1-induced down-regulation of aggrecan gene expression in human chondrocytes. Int J Mol Med 17:661-668
    • (2006) Int J Mol Med , vol.17 , pp. 661-668
    • Radons, J.1    Bosserhoff, A.K.2    Grassel, S.3
  • 268
    • 33644864148 scopus 로고    scopus 로고
    • Interleukin-10 does not affect IL-1-induced interleukin-6 and metalloproteinase production in human chondrosarcoma cells, SW1353
    • Radons J, Falk W, Schubert TE (2006 b ) Interleukin-10 does not affect IL-1-induced interleukin-6 and metalloproteinase production in human chondrosarcoma cells, SW1353. Int J Mol Med 17:377-383
    • (2006) Int J Mol Med , vol.17 , pp. 377-383
    • Radons, J.1    Falk, W.2    Schubert, T.E.3
  • 269
    • 77956621053 scopus 로고    scopus 로고
    • Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells
    • Rao PK, Missiaglia E, Shields L et al (2010) Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells. FASEB J 24:3427-3437
    • (2010) FASEB J , vol.24 , pp. 3427-3437
    • Rao, P.K.1    Missiaglia, E.2    Shields, L.3
  • 270
    • 22344443289 scopus 로고    scopus 로고
    • Celecoxib inhibits angiogenesis by inducing endothelial cell apoptosis in human pancreatic tumor xe nografts
    • Raut CP, Nawrocki S, Lashinger LM et al (2004) Celecoxib inhibits angiogenesis by inducing endothelial cell apoptosis in human pancreatic tumor xe nografts. Cancer Biol Ther 3:1217-1224
    • (2004) Cancer Biol Ther , vol.3 , pp. 1217-1224
    • Raut, C.P.1    Nawrocki, S.2    Lashinger, L.M.3
  • 271
    • 84857427678 scopus 로고    scopus 로고
    • Sorafenib for patients with advanced angiosarcoma: A phase II Trial from the French Sarcoma Group (GSF/GETO
    • Ray-Coquard I, Italiano A, Bompas E et al (2012) Sorafenib for patients with advanced angiosarcoma: a phase II Trial from the French Sarcoma Group (GSF/GETO). Oncologist 17:260-266
    • (2012) Oncologist , vol.17 , pp. 260-266
    • Ray-Coquard, I.1    Italiano, A.2    Bompas, E.3
  • 272
    • 79954464419 scopus 로고    scopus 로고
    • Celecoxib inhibits STAT3 phosphorylation and suppresses cell migration and colony forming ability in rhabdomyosarcoma cells
    • Reed S, Li H, Li C et al (2011) Celecoxib inhibits STAT3 phosphorylation and suppresses cell migration and colony forming ability in rhabdomyosarcoma cells. Biochem Biophys Res Commun 407:450-455
    • (2011) Biochem Biophys Res Commun , vol.407 , pp. 450-455
    • Reed, S.1    Li, H.2    Li, C.3
  • 274
    • 78049370987 scopus 로고    scopus 로고
    • Oxidative stress, inflammation, and cancer: How are they linked?
    • Reuter S, Gupta SC, Chaturvedi MM et al (2010) Oxidative stress, inflammation, and cancer: how are they linked? Free Radic Biol Med 49:1603-1616
    • (2010) Free Radic Biol Med , vol.49 , pp. 1603-1616
    • Reuter, S.1    Gupta, S.C.2    Chaturvedi, M.M.3
  • 275
    • 77951785861 scopus 로고    scopus 로고
    • EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells
    • Riggi N, Suva ML, De Vito C et al (2010) EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells. Genes Dev 24:916-932
    • (2010) Genes Dev , vol.24 , pp. 916-932
    • Riggi, N.1    Suva, M.L.2    De Vito, C.3
  • 276
    • 79551717942 scopus 로고    scopus 로고
    • Notch pathway inhibition significantly reduces rhabdomyosarcoma invasiveness and mobility in vitro
    • Roma J, Masia A, Reventos J et al (2011) Notch pathway inhibition significantly reduces rhabdomyosarcoma invasiveness and mobility in vitro. Clin Cancer Res 17:505-513
    • (2011) Clin Cancer Res , vol.17 , pp. 505-513
    • Roma, J.1    Masia, A.2    Reventos, J.3
  • 277
    • 33947500486 scopus 로고    scopus 로고
    • Cytokines are a therapeutic target for the prevention of inflammation-induced cancers
    • Rose-John S, Schooltink H (2007) Cytokines are a therapeutic target for the prevention of inflammation-induced cancers. Recent Results Cancer Res 174:57-66
    • (2007) Recent Results Cancer Res , vol.174 , pp. 57-66
    • Rose-John, S.1    Schooltink, H.2
  • 278
    • 77953965177 scopus 로고    scopus 로고
    • Partial response to bevacizumab of an extensive cutaneous angiosarcoma of the face
    • Rosen A, Thimon S, Ternant D et al (2010) Partial response to bevacizumab of an extensive cutaneous angiosarcoma of the face. Br J Dermatol 163:225-227
    • (2010) Br J Dermatol , vol.163 , pp. 225-227
    • Rosen, A.1    Thimon, S.2    Ternant, D.3
  • 279
    • 0022930029 scopus 로고
    • Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues
    • Rosen N, Bolen JB, Schwartz AM et al (1986) Analysis of pp60c-src protein kinase activity in human tumor cell lines and tissues. J Biol Chem 261:13754-13759
    • (1986) J Biol Chem , vol.261 , pp. 13754-13759
    • Rosen, N.1    Bolen, J.B.2    Schwartz, A.M.3
  • 280
    • 84885383985 scopus 로고    scopus 로고
    • The biology of Ewing sarcoma
    • doi:10.1155/2013/759725
    • Ross KA, Smyth NA, Murawski CD et al (2013) The biology of Ewing sarcoma. ISRN Oncol 2013:759725. doi:10.1155/2013/759725
    • (2013) ISRN Oncol , vol.2013 , pp. 759725
    • Ross, K.A.1    Smyth, N.A.2    Murawski, C.D.3
  • 281
    • 0036211528 scopus 로고    scopus 로고
    • A listing of skin conditions exhibiting the Koebner and pseudo-Koebner phenomena with eliciting stimuli
    • Rubin AI, Stiller MJ (2002) A listing of skin conditions exhibiting the Koebner and pseudo-Koebner phenomena with eliciting stimuli. J Cutan Med Surg 6:29-34
    • (2002) J Cutan Med Surg , vol.6 , pp. 29-34
    • Rubin, A.I.1    Stiller, M.J.2
  • 283
    • 79751484162 scopus 로고    scopus 로고
    • Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma
    • Rubin BP, Nishijo K, Chen HI et al (2011) Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma. Cancer Cell 19:177-191
    • (2011) Cancer Cell , vol.19 , pp. 177-191
    • Rubin, B.P.1    Nishijo, K.2    Chen, H.I.3
  • 284
    • 0242361563 scopus 로고    scopus 로고
    • Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: Correlations with local tumor extent and prognosis
    • R utkowski P, Kaminska J, Kowalska M et al (2003) Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: correlations with local tumor extent and prognosis. J Surg Oncol 84:151-159
    • (2003) J Surg Oncol , vol.84 , pp. 151-159
    • Utkowski P, R.1    Kaminska, J.2    Kowalska, M.3
  • 285
    • 63149182116 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus upregulates angiogenin during infection of human dermal microvascular endothelial cells, which induces 45S rRNA synthesis, antiapoptosis, cell proliferation, migration, and angiogenesis
    • Sa dagopan S, Sharma-Walia N, Veettil MV et al (2009) Kaposi's sarcoma-associated herpesvirus upregulates angiogenin during infection of human dermal microvascular endothelial cells, which induces 45S rRNA synthesis, antiapoptosis, cell proliferation, migration, and angiogenesis. J Virol 83:3342-3364
    • (2009) J Virol , vol.83 , pp. 3342-3364
    • Sa Dagopan, S.1    Sharma-Walia, N.2    Veettil, M.V.3
  • 286
    • 84869504554 scopus 로고    scopus 로고
    • Angiogenin functionally interacts with p53 and regulates p53-mediated apoptosis and cell survival
    • Sadagopan S, Veettil MV, Chakraborty S et al (2012) Angiogenin functionally interacts with p53 and regulates p53-mediated apoptosis and cell survival. Oncogene 31:4835-4847
    • (2012) Oncogene , vol.31 , pp. 4835-4847
    • Sadagopan, S.1    Veettil, M.V.2    Chakraborty, S.3
  • 287
    • 0034638623 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway
    • Sandau KB, Faus HG, Brune B (2000) Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway. Biochem Biophys Res Commun 278:263-267
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 263-267
    • Sandau, K.B.1    Faus, H.G.2    Brune, B.3
  • 288
    • 0031566814 scopus 로고    scopus 로고
    • Adjuvant chemotherapy for localised resectable soft-tissue sarcoma of adults: Meta-analysis of individual data
    • Sarcoma Meta-analysis Collaboration
    • Sarcoma Meta-analysis Collaboration (1997) Adjuvant chemotherapy for localised resectable soft-tissue sarcoma of adults: meta-analysis of individual data. Sarcoma Meta-analysis Collaboration. Lancet 350:1647-1654
    • (1997) Sarcoma Meta-analysis Collaboration. Lancet , vol.350 , pp. 1647-1654
  • 289
    • 79953235832 scopus 로고    scopus 로고
    • The role of MAPK pathway in bone and soft tissue tumors
    • Sasaki K, Hitora T, Nakamura O et al (2011) The role of MAPK pathway in bone and soft tissue tumors. Anticancer Res 31:549-553
    • (2011) Anticancer Res , vol.31 , pp. 549-553
    • Sasaki, K.1    Hitora, T.2    Nakamura, O.3
  • 290
    • 48749104292 scopus 로고    scopus 로고
    • The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma
    • Sasaki M, Ikeda H, Itatsu K et al (2008) The overexpression of polycomb group proteins Bmi1 and EZH2 is associated with the progression and aggressive biological behavior of hepatocellular carcinoma. Lab Invest 88:873-882
    • (2008) Lab Invest , vol.88 , pp. 873-882
    • Sasaki, M.1    Ikeda, H.2    Itatsu, K.3
  • 291
    • 0345061664 scopus 로고    scopus 로고
    • Aural cholesteatoma: Role of tumor necrosis factoralpha in bone destruction
    • Sastry KV, Sharma SC, Mann SB et al (1999) Aural cholesteatoma: role of tumor necrosis factoralpha in bone destruction. Am J Otol 20:158-161
    • (1999) Am J Otol , vol.20 , pp. 158-161
    • Sastry, K.V.1    Sharma, S.C.2    Mann, S.B.3
  • 292
    • 79955086282 scopus 로고    scopus 로고
    • Using epidemiology and genomics to understand osteosarcoma etiology
    • doi:10.1155/2011/548151
    • Savage SA, Mirabello L (2011) Using epidemiology and genomics to understand osteosarcoma etiology. Sarcoma 2011:548151. doi:10.1155/2011/548151
    • (2011) Sarcoma , vol.2011 , pp. 548151
    • Savage, S.A.1    Mirabello, L.2
  • 293
    • 0029796402 scopus 로고    scopus 로고
    • The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture
    • Scheidler S, Fredericks WJ, Rauscher FJ III et al (1996) The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture. Proc Natl Acad Sci USA 93:9805-9809
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9805-9809
    • Scheidler, S.1    Fredericks, W.J.2    Rauscher III, F.J.3
  • 294
    • 0037047477 scopus 로고    scopus 로고
    • Inverse relationship between p27/ Kip.1 and the F-box protein Skp2 in human astrocytic gliomas by immunohistochemistry and Western blot
    • Schiffer D, Cavalla P, Fiano V et al (2002) Inverse relationship between p27/ Kip.1 and the F-box protein Skp2 in human astrocytic gliomas by immunohistochemistry and Western blot. Neurosci Lett 328:125-128
    • (2002) Neurosci Lett , vol.328 , pp. 125-128
    • Schiffer, D.1    Cavalla, P.2    Fiano, V.3
  • 295
    • 80054078985 scopus 로고    scopus 로고
    • Phase II trial of anti-IGF-IR ant ibody cixutumumab in patients with advanced or metastatic soft-tissue sarcoma and Ewing family of tumors
    • Schoffski P, Adkins D, Blay J et al (2011a) Phase II trial of anti-IGF-IR ant ibody cixutumumab in patients with advanced or metastatic soft-tissue sarcoma and Ewing family of tumors. J Clin Oncol 29:10004. http://meeting. ascopubs.org/cgi/content/abstract/29/15-suppl/10004? sid=a6464a16-77fd-4537- baa7-c98ad3b1 e0bc
    • (2011) J Clin Oncol , vol.29 , pp. 10004
    • Schoffski, P.1    Adkins, D.2    Blay, J.3
  • 296
    • 80053383254 scopus 로고    scopus 로고
    • Activity of eribulin mesylate in patients with soft-tissue sarcoma: A phase 2 study in four independent histological subtypes
    • Schoffski P, Ray-Coquard IL, Cioffi A et al (2011b) Activity of eribulin mesylate in patients with soft-tissue sarcoma: a phase 2 study in four independent histological subtypes. Lancet Oncol 12:1045-10 52
    • (2011) Lancet Oncol , vol.12 , pp. 1045-1052
    • Schoffski, P.1    Ray-Coquard, I.L.2    Cioffi, A.3
  • 297
    • 84861335102 scopus 로고    scopus 로고
    • Results of a phase II study of sirolimus and cyclophosphamide in patients with advanced sarcoma
    • Schuetze SM, Zhao L, Chugh R et al (2012) Results of a phase II study of sirolimus and cyclophosphamide in patients with advanced sarcoma. Eur J Cancer 48:1347-1353
    • (2012) Eur J Cancer , vol.48 , pp. 1347-1353
    • Schuetze, S.M.1    Zhao, L.2    Chugh, R.3
  • 298
    • 84855541297 scopus 로고    scopus 로고
    • Brivanib (BMS-582664) in advanced soft-tissue sarcoma (STS): Biomarker and subset results of a phase II randomized discontinuation trial
    • Schwartz GK, Maki RG, Undevia SD et al (2011) Brivanib (BMS-582664) in advanced soft-tissue sarcoma (STS): biomarker and subset results of a phase II randomized discontinuation trial. J Clin Oncol 29:1000
    • (2011) J Clin Oncol , vol.29 , pp. 1000
    • Schwartz, G.K.1    Maki, R.G.2    Undevia, S.D.3
  • 299
    • 84871638156 scopus 로고    scopus 로고
    • A phase II multicenter study of the IGF-1 receptor antibody cixutumumab (A12) and the mTOR inhibitor temsirolimus (TEM) in patients (pts) with refractory IGF-1R positive (+) and negative (- ) bone and soft tissue sarcomas (STS
    • Schwartz GK, Tap WD, Qin LX et al (2012) A phase II multicenter study of the IGF-1 receptor antibody cixutumumab (A12) and the mTOR inhibitor temsirolimus (TEM) in patients (pts) with refractory IGF-1R positive (+) and negative (- ) bone and soft tissue sarcomas (STS). J Clin Oncol 30:10003. http://meeting.ascopubs.org/cgi/content/abstract/30/15-suppl/10003 ?sid=80ce8716-8c84-4aa3-a0db-6843813c51d1
    • (2012) J Clin Oncol , vol.30 , pp. 10003
    • Schwartz, G.K.1    Tap, W.D.2    Qin, L.X.3
  • 300
    • 0036722799 scopus 로고    scopus 로고
    • Expression of an IGF-I receptor dominant negative mutant induces apoptosis, inhibits tumorigenesis and enhances chemosensitivity in Ewing's sarcoma cells
    • Scotlandi K, Avnet S, Benini S et a l (2002) Expression of an IGF-I receptor dominant negative mutant induces apoptosis, inhibits tumorigenesis and enhances chemosensitivity in Ewing's sarcoma cells. Int J Cancer 101:11-16
    • (2002) Int J Cancer , vol.101 , pp. 11-16
    • Scotlandi, K.1    Avnet, S.2    Benini, S.3
  • 301
    • 0029993450 scopus 로고    scopus 로고
    • Role of the INK4a locus in tumor suppression and cell mortality
    • Serrano M, Lee H, C hin L et al (1996) Role of the INK4a locus in tumor suppression and cell mortality. Cell 85:27-37
    • (1996) Cell , vol.85 , pp. 27-37
    • Serrano, M.1    Lee, H.2    Hin L, C.3
  • 303
    • 77649258068 scopus 로고    scopus 로고
    • Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: A key factor in latency, inflammation, angiogenesis, cell survival and invasion
    • Sharma-Walia N, Paul AG, Bottero V et al (2010) Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion. PLoS Pathog 6:e1000777
    • (2010) PLoS Pathog , vol.6
    • Sharma-Walia, N.1    Paul, A.G.2    Bottero, V.3
  • 304
    • 33745286003 scopus 로고    scopus 로고
    • Cyclooxygenase 2 induced by Kaposi's sarcoma-associated herpesvirus early during in vitro infection of target cells plays a role in the maintenance of latent viral gene express ion
    • Sharma-Walia N, Raghu H, Sadagopan S et al (2006) Cyclooxygenase 2 induced by Kaposi's sarcoma-associated herpesvirus early during in vitro infection of target cells plays a role in the maintenance of latent viral gene express ion. J Virol 80:6534-6552
    • (2006) J Virol , vol.80 , pp. 6534-6552
    • Sharma-Walia, N.1    Raghu, H.2    Sadagopan, S.3
  • 305
    • 23044467557 scopus 로고    scopus 로고
    • Mechanism of constitutive phosphoinositide 3-kinase activation by oncogenic mutants of the p85 regulatory subunit
    • Shekar SC, Wu H, Fu Z et al (2005) Mechanism of constitutive phosphoinositide 3-kinase activation by oncogenic mutants of the p85 regulatory subunit. J Biol Chem 280: 27850-27855
    • (2005) J Biol Chem , vol.280 , pp. 27850-27855
    • Shekar, S.C.1    Wu, H.2    Fu, Z.3
  • 306
    • 84864037660 scopus 로고    scopus 로고
    • More than just skin deep: Faciocutaneous clues to genetic syndromes with malignancies
    • Shen Z, Hoffman JD, Hao F et al (2012) More than just skin deep: faciocutaneous clues to genetic syndromes with malignancies. Oncologist 17:930-936
    • (2012) Oncologist , vol.17 , pp. 930-936
    • Shen, Z.1    Hoffman, J.D.2    Hao, F.3
  • 307
    • 33747858764 scopus 로고    scopus 로고
    • The value of MDM2 and CDK4 amplification levels using real-time polymerase chain reaction for the differential diagnosis of liposarcomas and their histologic mimickers
    • Shimada S Ishizawa T Ishizawa K et al 2006 The value of MDM2 and CDK4 amplification levels using real-time polymerase chain reaction for the differential diagnosis of liposarcomas and their histologic mimickers Hum Pathol 37: 1123-1129
    • (2006) Hum Pathol , vol.37 , pp. 1123-1129
    • Shimada, S.1    Ishizawa, T.2    Ishizawa, K.3
  • 308
    • 34047265691 scopus 로고    scopus 로고
    • Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival
    • Shor AC, Keschman EA, Lee FY et al (2007) Dasatinib inhibits migration and invasion in diverse human sarcoma cell lines and induces apoptosis in bone sarcoma cells dependent on SRC kinase for survival. Cancer Res 67:2800-2808
    • (2007) Cancer Res , vol.67 , pp. 2800-2808
    • Shor, A.C.1    Keschman, E.A.2    Lee, F.Y.3
  • 309
    • 67649217824 scopus 로고    scopus 로고
    • Alterations in gene expression in human mesothelial cells correlate with mineral pathogenicity
    • Shukla A, MacPherson MB, Hillegass J et al (2009) Alterations in gene expression in human mesothelial cells correlate with mineral pathogenicity. Am J Respir Cell Mol Biol 41:114-123
    • (2009) Am J Respir Cell Mol Biol , vol.41 , pp. 114-123
    • Shukla, A.1    Macpherson, M.B.2    Hillegass, J.3
  • 310
    • 84858684687 scopus 로고    scopus 로고
    • Rank/Rankl/opg: Literature review
    • Silva I, Branco JC (2011) Rank/Rankl/opg: literature review. Acta Reumatol Port 36:209-218
    • (2011) Acta Reumatol Port , vol.36 , pp. 209-218
    • Silva, I.1    Branco, J.C.2
  • 311
    • 0036435625 scopus 로고    scopus 로고
    • Interleukin-1 beta increases the BCL-2/BAX ratio in Kaposi's sarcoma cells
    • Simonart T, Van Vooren JP (2002) Interleukin-1 beta increases the BCL-2/BAX ratio in Kaposi's sarcoma cells. Cytokine 19:259-266
    • (2002) Cytokine , vol.19 , pp. 259-266
    • Simonart, T.1    Van Vooren, J.P.2
  • 312
    • 79951770891 scopus 로고    scopus 로고
    • Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1
    • Singh M, Pandey A, Karikari CA et al (2010) Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1. Med Oncol 27:1096-1101
    • (2010) Med Oncol , vol.27 , pp. 1096-1101
    • Singh, M.1    Pandey, A.2    Karikari, C.A.3
  • 313
    • 33846508581 scopus 로고    scopus 로고
    • Adult human sarcomas I. Basic science
    • Sinkovics JG (2007 a ) Adult human sarcomas. I. Basic science. Expert Rev Anticancer Ther 7:31-56
    • (2007) Expert Rev Anticancer Ther , vol.7 , pp. 31-56
    • Sinkovics, J.G.1
  • 314
    • 33847240144 scopus 로고    scopus 로고
    • Adult human sarcomas. II. Medical oncology
    • Sinkovics JG (2007 b ) Adult human sarcomas. II. Medical oncology. Expert Rev Anticancer Ther 7:183-210
    • (2007) Expert Rev Anticancer Ther , vol.7 , pp. 183-210
    • Sinkovics, J.G.1
  • 315
    • 84855693136 scopus 로고    scopus 로고
    • Molecular biology of oncogenic inflammatory processes. I. Non-oncogenic and oncogenic pathogens, intrinsic inf lammatory reactions without pathogens, and micro-RNA/DNA interactions (Review
    • Sinkovics JG (2012) Molecular biology of oncogenic inflammatory processes. I. Non-oncogenic and oncogenic pathogens, intrinsic inf lammatory reactions without pathogens, and micro-RNA/DNA interactions (Review). Int J Oncol 40:305-349
    • (2012) Int J Oncol , vol.40 , pp. 305-349
    • Sinkovics, J.G.1
  • 316
    • 38849143913 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus induces sustai ned levels of vascular endothelial growth factors A and C early during in vitro infection of human microvascular dermal endothelial cells: Biological implications
    • Sivakumar R, Sharma-Walia N, Raghu H et al (2008) Kaposi's sarcoma-associated herpesvirus induces sustai ned levels of vascular endothelial growth factors A and C early during in vitro infection of human microvascular dermal endothelial cells: biological implications. J Virol 82:1759-1776
    • (2008) J Virol , vol.82 , pp. 1759-1776
    • Sivakumar, R.1    Sharma-Walia, N.2    Raghu, H.3
  • 317
    • 22244463891 scopus 로고    scopus 로고
    • Paclitaxel and pegylated-liposomal doxorubicin are both active in angiosarcoma
    • Skubitz KM, Haddad PA (2005) Paclitaxel and pegylated-liposomal doxorubicin are both active in angiosarcoma. Cancer 104:361-366
    • (2005) Cancer , vol.104 , pp. 361-366
    • Skubitz, K.M.1    Haddad, P.A.2
  • 318
    • 71049122368 scopus 로고    scopus 로고
    • Prognostic and predictive factors for outcome to first-line ifosfamide-containing chemotherapy for adult patients with advanced soft tissue sarcomas: An exploratory, retrospective analysis on large series from the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group ( EORTC-STBSG
    • Sleijfer S, Ouali M, van Glabbeke M et al (2010) Prognostic and predictive factors for outcome to first-line ifosfamide-containing chemotherapy for adult patients with advanced soft tissue sarcomas: an exploratory, retrospective analysis on large series from the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group ( EORTC-STBSG). Eur J Cancer 46:72-83
    • (2010) Eur J Cancer , vol.46 , pp. 72-83
    • Sleijfer, S.1    Ouali, M.2    Van Glabbeke, M.3
  • 319
    • 67650337802 scopus 로고    scopus 로고
    • Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: A phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC study 62043
    • Sleijfer S, Ray-Coquard I, Papai Z et al (2009) Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC study 62043). J Clin Oncol 27:3126-3132
    • (2009) J Clin Oncol , vol.27 , pp. 3126-3132
    • Sleijfer, S.1    Ray-Coquard, I.2    Papai, Z.3
  • 320
    • 77955744323 scopus 로고    scopus 로고
    • Genomic alterations and allelic imbalances are strong prognostic predictors in osteosarcoma
    • Smida J, Baumhoer D, Rosemann M et al (2010) Genomic alterations and allelic imbalances are strong prognostic predictors in osteosarcoma. Clin Cancer Res 16:4256-4267
    • (2010) Clin Cancer Res , vol.16 , pp. 4256-4267
    • Smida, J.1    Baumhoer, D.2    Rosemann, M.3
  • 321
    • 7944223098 scopus 로고    scopus 로고
    • Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis
    • Sparmann A, Bar-Sagi D (2004) Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis. Cancer Cell 6:447-458
    • (2004) Cancer Cell , vol.6 , pp. 447-458
    • Sparmann, A.1    Bar-Sagi, D.2
  • 322
    • 16244423721 scopus 로고    scopus 로고
    • Prognostic factors in advanced synovial sarcoma: An analysis of 104 patients treated at the R oyal Marsden Hospital
    • Spurrell EL, Fisher C, Thomas JM et al (2005) Prognostic factors in advanced synovial sarcoma: an analysis of 104 patients treated at the R oyal Marsden Hospital. Ann Oncol 16:437-444
    • (2005) Ann Oncol , vol.16 , pp. 437-444
    • Spurrell, E.L.1    Fisher, C.2    Thomas, J.M.3
  • 323
    • 84885946639 scopus 로고    scopus 로고
    • Extraskeletal myxoid chondrosarcoma: Tumor response to sunitinib
    • doi:10.1186/2045-3329-2-22
    • Stacchiotti S, Dagrada GP, Morosi C et al (2012a) Extraskeletal myxoid chondrosarcoma: tumor response to sunitinib. Clin Sarcoma Res 2:22. doi:10.1186/2045-3329-2-22
    • (2012) Clin Sarcoma Res , vol.2 , pp. 22
    • Stacchiotti, S.1    Dagrada, G.P.2    Morosi, C.3
  • 324
    • 84869792128 scopus 로고    scopus 로고
    • Sunitinib malate in solitary fibrous tumor (SFT
    • Stacchiotti S, Negri T, Libertini M et al (2012b) Sunitinib malate in solitary fibrous tumor (SFT). Ann Oncol 23:3171-3179
    • (2012) Ann Oncol , vol.23 , pp. 3171-3179
    • Stacchiotti, S.1    Negri, T.2    Libertini, M.3
  • 325
    • 21344470873 scopus 로고    scopus 로고
    • Lyn kinase activity is the predominant cellular SRC kinase activity in glioblastoma tumor cells
    • Stettner MR, Wang W, Nabors LB et al (2005) Lyn kinase activity is the predominant cellular SRC kinase activity in glioblastoma tumor cells. Cancer Res 65:5535-5543
    • (2005) Cancer Res , vol.65 , pp. 5535-5543
    • Stettner, M.R.1    Wang, W.2    Nabors, L.B.3
  • 326
    • 84872678571 scopus 로고    scopus 로고
    • Descriptive epidemiology of sarcomas in Europe: Report from the RARECARE project
    • Stiller CA, Trama A, Serraino D et al (2013) Descriptive epidemiology of sarcomas in Europe: report from the RARECARE project. Eur J Cancer 49:684-695
    • (2013) Eur J Cancer , vol.49 , pp. 684-695
    • Stiller, C.A.1    Trama, A.2    Serraino, D.3
  • 327
    • 0036192221 scopus 로고    scopus 로고
    • Analysis of the prognostic significance of microscopic margins in 2,084 localized primary adult soft tissue sarcomas
    • Stojadinovic A, Leung DH, Hoos A et al (2002) Analysis of the prognostic significance of microscopic margins in 2,084 localized primary adult soft tissue sarcomas. Ann Surg 235:424-434
    • (2002) Ann Surg , vol.235 , pp. 424-434
    • Stojadinovic, A.1    Leung, D.H.2    Hoos, A.3
  • 328
    • 0038686947 scopus 로고    scopus 로고
    • Sarcomas of the head and neck region
    • Sturgis EM Potter BO 2003Sarcomas of the head and neck region Curr Opin Oncol 15:239-252
    • (2003) Curr Opin Oncol , vol.15 , pp. 239-252
    • Sturgis, E.M.1    Potter, B.O.2
  • 329
    • 41149100145 scopus 로고    scopus 로고
    • MicroRNA expression signature of human sarcomas
    • Subramanian S, Lui WO, Lee CH et al (2008) MicroRNA expression signature of human sarcomas. Oncogene 27:2015-2026
    • (2008) Oncogene , vol.27 , pp. 2015-2026
    • Subramanian, S.1    Lui, W.O.2    Lee, C.H.3
  • 330
    • 84873646761 scopus 로고    scopus 로고
    • DNA helicases associated with genetic instability, cancer, and aging
    • Suhasini AN, Brosh RM Jr (2013) DNA helicases associated with genetic instability, cancer, and aging. Adv Exp Med Biol 767:123-144
    • (2013) Adv Exp Med Biol , vol.767 , pp. 123-144
    • Suhasini, A.N.1    Brosh Jr., R.M.2
  • 331
    • 33645987648 scopus 로고    scopus 로고
    • Bone stromal cells in pagetic bone and Paget's sarcoma express RANKL and support human osteoclast formation
    • Sun SG, Lau YS, Itonaga I e t al (2006) Bone stromal cells in pagetic bone and Paget's sarcoma express RANKL and support human osteoclast formation. J Pathol 209:114-120
    • (2006) J Pathol , vol.209 , pp. 114-120
    • Sun, S.G.1    Lau, Y.S.2    Itonaga, I.3
  • 333
    • 0037051673 scopus 로고    scopus 로고
    • Osteopontin induces angiogenesis of murine neuroblastoma cells in mice
    • Takahashi F, Akutagawa S, Fukumoto H et al (2002) Osteopontin induces angiogenesis of murine neuroblastoma cells in mice. Int J Cancer 98:707-712
    • (2002) Int J Cancer , vol.98 , pp. 707-712
    • Takahashi, F.1    Akutagawa, S.2    Fukumoto, H.3
  • 334
    • 0033917904 scopus 로고    scopus 로고
    • Autocrine growth effect of IL-8 and GROα on a human pancreatic cancer cell line
    • Takamori H, Oades ZG, Hoch OC et al (2000) Autocrine growth effect of IL-8 and GROα on a human pancreatic cancer cell line, Capan-1. Pancreas 21:52-56
    • (2000) Capan-1. Pancreas , vol.21 , pp. 52-56
    • Takamori, H.1    Oades, Z.G.2    Hoch, O.C.3
  • 335
    • 79551600015 scopus 로고    scopus 로고
    • Targeting cancer stem cells by inhibiting Wnt,Notch, and Hedgehog pathways
    • Takebe N, Harris PJ, Warren RQ et al (2011) Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol 8:97-106
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 97-106
    • Takebe, N.1    Harris, P.J.2    Warren, R.Q.3
  • 336
    • 78049516078 scopus 로고    scopus 로고
    • Gen e expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma
    • doi:10.1186/1471-2407-10-619
    • Tamburini BA, Phang TL, Fosmire SP et al (2010) Gen e expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma. BMC Cancer 10:619. doi:10.1186/1471-2407-10-619
    • (2010) BMC Cancer , vol.10 , pp. 619
    • Tamburini, B.A.1    Phang, T.L.2    Fosmire, S.P.3
  • 337
    • 67349182923 scopus 로고    scopus 로고
    • Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation
    • Tanaka M, Setoguchi T, Hirotsu M et al (2009) Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation. Br J Cancer 100:1957-1965
    • (2009) Br J Cancer , vol.100 , pp. 1957-1965
    • Tanaka, M.1    Setoguchi, T.2    Hirotsu, M.3
  • 338
    • 84863908472 scopus 로고    scopus 로고
    • Phase II study of ganitumab, a ful ly human antitype-1 insulin-like growth factor receptor antibody, in patients with metastatic Ewing family tumors or desmoplastic small round cell tumors
    • Tap WD, Demetri G, Barnette P et al (2012) Phase II study of ganitumab, a ful ly human antitype-1 insulin-like growth factor receptor antibody, in patients with metastatic Ewing family tumors or desmoplastic small round cell tumors. J Clin Oncol 30:1849-1856
    • (2012) J Clin Oncol , vol.30 , pp. 1849-1856
    • Tap, W.D.1    Demetri, G.2    Barnette, P.3
  • 339
    • 65949100790 scopus 로고    scopus 로고
    • New perspective in osteoarthritis:The OPG and RANKL system as a potential therapeutic target?
    • Tat SK, Pelletier JP, Velasco CR et al (2009) New perspective in osteoarthritis: the OPG and RANKL system as a potential therapeutic target? Keio J Med 58:29-40
    • (2009) Keio J Med , vol.58 , pp. 29-40
    • Tat, S.K.1    Pelletier, J.P.2    Velasco, C.R.3
  • 340
    • 68849118992 scopus 로고    scopus 로고
    • The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation
    • Taulli R, Bersani F, Foglizzo V et al (2009) The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation. J Clin Invest 119:2366-2378
    • (2009) J Clin Invest , vol.119 , pp. 2366-2378
    • Taulli, R.1    Bersani, F.2    Foglizzo, V.3
  • 341
    • 80052455224 scopus 로고    scopus 로고
    • Ewing sarcoma cells express RANKL and support osteoclastogenesis
    • Taylor R, Knowles HJ, Athanasou NA (2011) Ewing sarcoma cells express RANKL and support osteoclastogenesis. J Pathol 225:195-202
    • (2011) J Pathol , vol.225 , pp. 195-202
    • Taylor, R.1    Knowles, H.J.2    Athanasou, N.A.3
  • 342
    • 36849071808 scopus 로고    scopus 로고
    • Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment
    • Thomas ES, Gomez HL, Li RK et al (2007) Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment. J Clin Oncol 25:5210-5217
    • (2007) J Clin Oncol , vol.25 , pp. 5210-5217
    • Thomas, E.S.1    Gomez, H.L.2    Li, R.K.3
  • 343
    • 79953197948 scopus 로고    scopus 로고
    • Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer
    • Tili E, Michaille JJ, Wernicke D et al (2011) Mutator activity induced by microRNA-155 (miR-155) links inflammation and cancer. Proc Natl Acad Sci USA 108:4908-4913
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4908-4913
    • Tili, E.1    Michaille, J.J.2    Wernicke, D.3
  • 344
    • 73349099049 scopus 로고    scopus 로고
    • Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1
    • Tolcher AW, Sarantopoulos J, Patnaik A et al (2009) Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1. J Clin Oncol 27:5800-5807
    • (2009) J Clin Oncol , vol.27 , pp. 5800-5807
    • Tolcher, A.W.1    Sarantopoulos, J.2    Patnaik, A.3
  • 345
    • 18544365990 scopus 로고    scopus 로고
    • Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
    • Tomlinson IP, Alam NA, Rowan AJ et al (2002) Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer. Nat Genet 30:406-410
    • (2002) Nat Genet , vol.30 , pp. 406-410
    • Tomlinson, I.P.1    Alam, N.A.2    Rowan, A.J.3
  • 346
    • 75249095926 scopus 로고    scopus 로고
    • IGF-1R targeted treatment of sarcoma
    • Toretsky JA, Gorlick R (2010) IGF-1R targeted treatment of sarcoma. Lancet Oncol 11:105-106
    • (2010) Lancet Oncol , vol.11 , pp. 105-106
    • Toretsky, J.A.1    Gorlick, R.2
  • 347
    • 33751585501 scopus 로고    scopus 로고
    • Incidence patterns of soft tissue sarcomas, regardless of primary site, in the surveil lance, epidemiology and end results program, 1978-2001: An analysis of 26,758 cases
    • Toro JR, Travis LB, Wu HJ et al (2006) Incidence patterns of soft tissue sarcomas, regardless of primary site, in the surveil lance, epidemiology and end results program, 1978-2001: an analysis of 26,758 cases. Int J Cancer 119:2922-2930
    • (2006) Int J Cancer , vol.119 , pp. 2922-2930
    • Toro, J.R.1    Travis, L.B.2    Wu, H.J.3
  • 348
    • 33845684374 scopus 로고    scopus 로고
    • Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice
    • Tsumura H, Yoshida T, Saito H et al (2006) Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice. Oncogene 25:7673-7679
    • (2006) Oncogene , vol.25 , pp. 7673-7679
    • Tsumura, H.1    Yoshida, T.2    Saito, H.3
  • 349
    • 70449535760 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression predicts poor survival in patients with hi gh-grade extremity osteosarcoma: A pilot study
    • Urakawa H, Nishida Y, Naruse T et al (2009) Cyclooxygenase-2 overexpression predicts poor survival in patients with hi gh-grade extremity osteosarcoma: a pilot study. Clin Orthop Relat Res 467:2932-2938
    • (2009) Clin Orthop Relat Res , vol.467 , pp. 2932-2938
    • Urakawa, H.1    Nishida, Y.2    Naruse, T.3
  • 350
    • 84864756216 scopus 로고    scopus 로고
    • Maintenance of clinical efficacy after dose reduction of ixabepilone plus capecita bine in patients with anthracycline-and taxane-resistant metastatic breast cancer: A retrospective analysis of pooled data from 2 phase III randomized clinical trials
    • Valero V, Vrdoljak E, Xu B et al (2012) Maintenance of clinical efficacy after dose reduction of ixabepilone plus capecita bine in patients with anthracycline-and taxane-resistant metastatic breast cancer: a retrospective analysis of pooled data from 2 phase III randomized clinical trials. Clin Breast Cancer 12:240-246
    • (2012) Clin Breast Cancer , vol.12 , pp. 240-246
    • Valero, V.1    Vrdoljak, E.2    Xu, B.3
  • 351
    • 0042425741 scopus 로고    scopus 로고
    • Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction
    • van den Boom J, Wolte r M, Kuick R et al (2003) Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction. Am J Pathol 163:1033-1043
    • (2003) Am J Pathol , vol.163 , pp. 1033-1043
    • Van Den Boom, J.1    Wolte, R.M.2    Kuick, R.3
  • 352
    • 84861098484 scopus 로고    scopus 로고
    • Pazopanib for metastatic soft-tissue sarcoma (PALETTE): A randomised, double-blind, placebo-controlled phase 3 trial
    • van der Graaf WT, Blay JY, Chawla SP et al (2012) Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet 379:1879-1886
    • (2012) Lancet , vol.379 , pp. 1879-1886
    • Van Der Graaf, W.T.1    Blay, J.Y.2    Chawla, S.P.3
  • 353
    • 0036892122 scopus 로고    scopus 로고
    • Results of randomised studies of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) with two different ifosfamide regimens in first-and second-line chemotherapy in ad vanced soft tissue sarcoma patients
    • van Oosterom AT, Mouridsen HT, Nielsen OS et al (2002) Results of randomised studies of the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) with two different ifosfamide regimens in first-and second-line chemotherapy in ad vanced soft tissue sarcoma patients. Eur J Cancer 38:2397-2406
    • (2002) Eur J Cancer , vol.38 , pp. 2397-2406
    • Van Oosterom, A.T.1    Mouridsen, H.T.2    Nielsen, O.S.3
  • 354
    • 79957509564 scopus 로고    scopus 로고
    • The emerging role of mammalian target of rapamycin inhibitors in the treatment of sarcomas
    • Vemulapalli S, Mita A, Alvarado Y et al (2011) The emerging role of mammalian target of rapamycin inhibitors in the treatment of sarcomas. Target Oncol 6:29-39
    • (2011) Target Oncol , vol.6 , pp. 29-39
    • Vemulapalli, S.1    Mita, A.2    Alvarado, Y.3
  • 355
    • 43949084697 scopus 로고    scopus 로고
    • Meta-analysis of ifosfamide-based combination chemotherapy in advanced soft tissue sarcoma
    • Verma S, Younus J, Stys-Norman D et al (2008) Meta-analysis of ifosfamide-based combination chemotherapy in advanced soft tissue sarcoma. Cancer Treat Rev 34:339-347
    • (2008) Cancer Treat Rev , vol.34 , pp. 339-347
    • Verma, S.1    Younus, J.2    Stys-Norman, D.3
  • 356
    • 77349116791 scopus 로고    scopus 로고
    • Future treatment of soft tissue sarcomas will be driven by histological subtype and molecular aberrations
    • Verweij J, Baker LH (2010) Future treatment of soft tissue sarcomas will be driven by histological subtype and molecular aberrations. Eur J Cancer 46:863-868
    • (2010) Eur J Cancer , vol.46 , pp. 863-868
    • Verweij, J.1    Baker, L.H.2
  • 357
    • 20844433223 scopus 로고    scopus 로고
    • Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: Randomised trial
    • Verweij J, Casali PG, Zalcberg J et al (2004) Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial. Lancet 364:1127-1134
    • (2004) Lancet , vol.364 , pp. 1127-1134
    • Verweij, J.1    Casali, P.G.2    Zalcberg, J.3
  • 360
    • 84856233838 scopus 로고    scopus 로고
    • Phase 2 Southwest Oncology Groupdirected intergroup trial (S0505) of sor afenib in advanced soft tissue sarcomas
    • von Mehren M, Rankin C, Goldblum JR et al (2012) Phase 2 Southwest Oncology Groupdirected intergroup trial (S0505) of sor afenib in advanced soft tissue sarcomas. Cancer 118:770-776
    • (2012) Cancer , vol.118 , pp. 770-776
    • Von Mehren, M.1    Rankin, C.2    Goldblum, J.R.3
  • 361
    • 34848903024 scopus 로고    scopus 로고
    • Role of IL-1-mediated inflammation in tumor angiogenesis
    • Voronov E, Carmi Y, Apte RN (2007) Role of IL-1-mediated inflammation in tumor angiogenesis. Adv Exp Med Biol 601:265-270
    • (2007) Adv Exp Med Biol , vol.601 , pp. 265-270
    • Voronov, E.1    Carmi, Y.2    Apte, R.N.3
  • 362
    • 84869493002 scopus 로고    scopus 로고
    • Tivantinib (ARQ 197), a selective inhibitor of MET, in patients with microphthalmia transcription factor-associated tumors: Results of a multicenter phase 2 trial
    • W agner AJ, Goldberg JM, Dubois SG et al (2012) Tivantinib (ARQ 197), a selective inhibitor of MET, in patients with microphthalmia transcription
    • (2012) Cancer , vol.118 , pp. 5894-5902
    • Wagner, A.J.1    Goldberg, J.M.2    Dubois, S.G.3
  • 363
    • 34548427415 scopus 로고    scopus 로고
    • The biology behind mTOR inhibition in sarcoma
    • Wan X, Helman LJ (2007) The biology behind mTOR inhibition in sarcoma. Oncologist 12:1007-1018
    • (2007) Oncologist , vol.12 , pp. 1007-1018
    • Wan, X.1    Helman, L.J.2
  • 364
    • 28544449224 scopus 로고    scopus 로고
    • Forkhead box M1 regulates th e transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase
    • Wang IC, Chen YJ, Hughes D et al (2005a ) Forkhead box M1 regulates th e transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. Mol Cell Biol 25:10875-10894
    • (2005) Mol Cell Biol , vol.25 , pp. 10875-10894
    • Wang, I.C.1    Chen, Y.J.2    Hughes, D.3
  • 365
    • 23044475761 scopus 로고    scopus 로고
    • Loss of tu mor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation
    • Wang J, Ouyang W, Li J et al (2005b ) Loss of tu mor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation. Cancer Res 65:6601-6611
    • (2005) Cancer Res , vol.65 , pp. 6601-6611
    • Wang, J.1    Ouyang, W.2    Li, J.3
  • 366
    • 0038288850 scopus 로고    scopus 로고
    • Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome
    • Wang LL, Gannavarapu A , Kozinetz CA et al (2003) Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome. J Natl Cancer Inst 95:669-674
    • (2003) J Natl Cancer Inst , vol.95 , pp. 669-674
    • Wang, L.L.1    Gannavarapu, A.2    Kozinetz, C.A.3
  • 367
    • 79958800720 scopus 로고    scopus 로고
    • FoxM1 in tumorigenicity of the neuroblastoma cells and renewal of the neural progenitors
    • Wang Z, Park HJ, Carr JR et a l (2011) FoxM1 in tumorigenicity of the neuroblastoma cells and renewal of the neural progenitors. Cancer Res 71:4292-4302
    • (2011) Cancer Res , vol.71 , pp. 4292-4302
    • Wang, Z.1    Park, H.J.2    Carr, J.R.3
  • 368
    • 0042338788 scopus 로고    scopus 로고
    • Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors
    • Wardelmann E, Losen I, Hans V et al (2003) Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors. Int J Cancer 106:887-895
    • (2003) Int J Cancer , vol.106 , pp. 887-895
    • Wardelmann, E.1    Losen, I.2    Hans, V.3
  • 369
    • 0033059976 scopus 로고    scopus 로고
    • Enhanc ement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice
    • Wilker E, Bol D, Kiguchi K et al (1999) Enhanc ement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice. Mol Carcinog 25:122-131
    • (1999) Mol Carcinog , vol.25 , pp. 122-131
    • Wilker, E.1    Bol, D.2    Kiguchi, K.3
  • 370
    • 0030848527 scopus 로고    scopus 로고
    • Cancer incidence after retinoblastoma Radiation dose and sarcoma risk
    • Wong FL, Boice JD Jr, Abramson DH et al (1997) Cancer incidence after retinoblastoma. Radiation dose and sarcoma risk. JAMA 278:1262-1267
    • (1997) JAMA , vol.278 , pp. 1262-1267
    • Wong, F.L.1    Boice Jr., J.D.2    Abramson, D.H.3
  • 371
    • 79957757038 scopus 로고    scopus 로고
    • Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition
    • Wong TF, Takeda T, Li B et al (2011) Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition. Gynecol Oncol 122:141-148
    • (2011) Gynecol Oncol , vol.122 , pp. 141-148
    • Wong, T.F.1    Takeda, T.2    Li, B.3
  • 372
    • 84865963859 scopus 로고    scopus 로고
    • Pardaxin, a fish antimicrobial peptide, exhibits antitumor activity toward murine fibrosarcoma in vitro and in vivo
    • Wu SP Huang TC Lin CC et al 2012) Pardaxin, a fish antimicrobial peptide, exhibits antitumor activity toward murine fibrosarcoma in vitro and in vivo. Mar Drugs 10: 1852-1872
    • (2012) Mar Drugs , vol.10 , pp. 1852-1872
    • Wu, S.P.1    Huang, T.C.2    Lin, C.C.3
  • 373
    • 77957734800 scopus 로고    scopus 로고
    • Celecoxib inhibits beta-catenin-dependent survival of the human osteosarcoma MG-63 cell line
    • Xia JJ, Pei LB, Zhuang JP et al (2010) Celecoxib inhibits beta-catenin-dependent survival of the human osteosarcoma MG-63 cell line. J Int Med Res 38:1294-1304
    • (2010) J Int Med Res , vol.38 , pp. 1294-1304
    • Xia, J.J.1    Pei, L.B.2    Zhuang, J.P.3
  • 374
    • 27544471889 scopus 로고    scopus 로고
    • Chromosome translocations in sarcomas and the emergence of oncogenic transcription factors
    • Xia SJ, Barr FG (2005) Chromosome translocations in sarcomas and the emergence of oncogenic transcription factors. Eur J Cancer 41:2513-2527
    • (2005) Eur J Cancer , vol.41 , pp. 2513-2527
    • Xia, S.J.1    Barr, F.G.2
  • 375
    • 80052833534 scopus 로고    scopus 로고
    • Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma
    • Xie X, Ghadimi MP, Young ED et al (2011) Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma. Clin Cancer Res 17:5901-5912
    • (2011) Clin Cancer Res , vol.17 , pp. 5901-5912
    • Xie, X.1    Ghadimi, M.P.2    Young, E.D.3
  • 376
    • 84869010521 scopus 로고    scopus 로고
    • Sirolimus for the treatment of Kaposi sarcoma after renal transplantation: A series of 10 cases
    • Yaich S, Charfeddine K, Zaghdane S et al (2012) Sirolimus for the treatment of Kaposi sarcoma after renal transplantation: a series of 10 cases. Transpl Proc 44:2824-2826
    • (2012) Transpl Proc , vol.44 , pp. 2824-2826
    • Yaich, S.1    Charfeddine, K.2    Zaghdane, S.3
  • 377
    • 70350383632 scopus 로고    scopus 로고
    • MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development
    • Yan D, Dong XE, Chen X et al (2009) MicroRNA-1/206 targets c-Met and inhibits rhabdomyosarcoma development. J Biol Chem 284:29596-29604
    • (2009) J Biol Chem , vol.284 , pp. 29596-29604
    • Yan, D.1    Dong, X.E.2    Chen, X.3
  • 378
    • 77950897711 scopus 로고    scopus 로고
    • The kinase Mirk is a potential therapeutic target in osteosarcoma
    • Yang C, Ji D, Weinstein EJ et al (2010a) The kinase Mirk is a potential therapeutic target in osteosarcoma. Carcinogenesis 31:552-558
    • (2010) Carcinogenesis , vol.31 , pp. 552-558
    • Yang, C.1    Ji, D.2    Weinstein, E.J.3
  • 379
    • 77957583439 scopus 로고    scopus 로고
    • Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition
    • Yang MH, Hsu DS, Wang HW et al (2010b) Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition. Nat Cell Biol 12:982-992
    • (2010) Nat Cell Biol , vol.12 , pp. 982-992
    • Yang, M.H.1    Hsu, D.S.2    Wang, H.W.3
  • 380
    • 34547907805 scopus 로고    scopus 로고
    • Expanding mTOR signaling
    • Yang Q, Guan KL (2007) Expanding mTOR signaling. Cell Res 17:666-681
    • (2007) Cell Res , vol.17 , pp. 666-681
    • Yang, Q.1    Guan, K.L.2
  • 381
    • 34648822606 scopus 로고    scopus 로고
    • Interleukin-8 modulates growth and invasiveness of estrogen receptor-negative breast cancer cells
    • Yao C, Lin Y, Chua MS et al (2007) Interleukin-8 modulates growth and invasiveness of estrogen receptor-negative breast cancer cells. Int J Cancer 121:1949-1957
    • (2007) Int J Cancer , vol.121 , pp. 1949-1957
    • Yao, C.1    Lin, Y.2    Chua, M.S.3
  • 382
    • 79958791448 scopus 로고    scopus 로고
    • Targeted therapies in bone sarcomas: Current approach and future directions
    • Yarber JL, Agulnik M (2011) Targeted therapies in bone sarcomas: current approach and future directions. Expert Opin Investig Drugs 20:973-979
    • (2011) Expert Opin Investig Drugs , vol.20 , pp. 973-979
    • Yarber, J.L.1    Agulnik, M.2
  • 383
    • 84860341318 scopus 로고    scopus 로고
    • Nutlin-3 induces apoptosis, disrupts viral latency and inhibits expression of angiopoietin-2 in Kaposi sarcoma tumor cells
    • Ye F, La ttif AA, Xie J et al (2012) Nutlin-3 induces apoptosis, disrupts viral latency and inhibits expression of angiopoietin-2 in Kaposi sarcoma tumor cells. Cell Cycle 11:1393-1399
    • (2012) Cell Cycle , vol.11 , pp. 1393-1399
    • Ye, F.1    La Ttif, A.A.2    Xie, J.3
  • 384
    • 17844377079 scopus 로고    scopus 로고
    • Effects of transforming growth factor beta 1 on the growth of rhabdomyosarcoma cell line RD
    • (Engl
    • Ye L, Zhang HY, Wang H et al (2005) Effects of transforming growth factor beta 1 on the growth of rhabdomyosarcoma cell line RD. Chin Med J 118:678-686 (Engl
    • (2005) Chin Med J , vol.118 , pp. 678-686
    • Ye, L.1    Zhang, H.Y.2    Wang, H.3
  • 385
    • 0036734818 scopus 로고    scopus 로고
    • Expression of epidermal growth factor, tumor necrosis factoralpha, and interleukin-1alpha in chronic otitis media with or without cholesteatoma
    • Yetiser S, Satar B, Aydin N (2002) Expression of epidermal growth factor, tumor necrosis factoralpha, and interleukin-1alpha in chronic otitis media with or without cholesteatoma. Otol Neurotol 23:647-652
    • (2002) Otol Neurotol , vol.23 , pp. 647-652
    • Yetiser, S.1    Satar, B.2    Aydin, N.3
  • 386
    • 0032819299 scopus 로고    scopus 로고
    • H-ras and K-ras gene mutations in primary human soft tissue sarcoma: Concomitant mutations of the ras genes
    • Yoo J, Robinson RA, Lee JY (1999) H-ras and K-ras gene mutations in primary human soft tissue sarcoma: concomitant mutations of the ras genes. Mod Pathol 12:775-780
    • (1999) Mod Pathol , vol.12 , pp. 775-780
    • Yoo, J.1    Robinson, R.A.2    Lee, J.Y.3
  • 387
    • 1542398698 scopus 로고    scopus 로고
    • Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients
    • Yovine A, Riofrio M, Blay JY et al (2004) Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients. J Clin Oncol 22:890-899
    • (2004) J Clin Oncol , vol.22 , pp. 890-899
    • Yovine, A.1    Riofrio, M.2    Blay, J.Y.3
  • 388
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: A leading role for STAT3
    • Yu H, Pardoll D, Jove R (2009) STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer 9:798-809
    • (2009) Nat Rev Cancer , vol.9 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 389
    • 1442304609 scopus 로고    scopus 로고
    • Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators
    • Yu Y, Khan J, Khanna C et al (2004) Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. Nat Me d 10:175-181
    • (2004) Nat Me D , vol.10 , pp. 175-181
    • Yu, Y.1    Khan, J.2    Khanna, C.3
  • 390
    • 77951709259 scopus 로고    scopus 로고
    • Targeting the insulin-like growth factor receptor-1R pathway for cancer therapy
    • Zha J, Lackner MR (2010) Targeting the insulin-like growth factor receptor-1R pathway for cancer therapy. Clin Cancer Res 16:2512-2517
    • (2010) Clin Cancer Res , vol.16 , pp. 2512-2517
    • Zha, J.1    Lackner, M.R.2
  • 391
    • 84859408905 scopus 로고    scopus 로고
    • MiR-155 is a liposarcoma oncogene that targets casein kinase-1alpha and enhances beta-catenin signaling
    • Zhang P, Bill K, Liu J et al (2012) MiR-155 is a liposarcoma oncogene that targets casein kinase-1alpha and enhances beta-catenin signaling. Cancer Res 72:1751-1762
    • (2012) Cancer Res , vol.72 , pp. 1751-1762
    • Zhang, P.1    Bill, K.2    Liu, J.3
  • 392
    • 55349089547 scopus 로고    scopus 로고
    • FoxM1B transcriptiona lly regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells
    • Zhang Y, Zhang N, Dai B et al (2008) FoxM1B transcriptiona lly regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells. Cancer Res 68:8733-8742
    • (2008) Cancer Res , vol.68 , pp. 8733-8742
    • Zhang, Y.1    Zhang, N.2    Dai, B.3
  • 393
    • 78649814616 scopus 로고    scopus 로고
    • Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma
    • Zibat A Missiaglia E Rosenberger A et al 2010 Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma Oncogene 29: 6323-6330
    • (2010) Oncogene , vol.29 , pp. 6323-6330
    • Zibat, A.1    Missiaglia, E.2    Rosenberger, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.