메뉴 건너뛰기




Volumn 137, Issue 6, 2011, Pages 1037-1051

Efficient virotherapy for osteosarcoma by telomerase-specific oncolytic adenovirus

Author keywords

Apoptosis; Oncolytic adenovirus; Osteosarcoma; Telomerase; Virotherapy

Indexed keywords

E1A PROTEIN; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; OBP 301; ONCOLYTIC ADENOVIRUS; TELOMELYSIN; UNCLASSIFIED DRUG;

EID: 79959770652     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-010-0969-6     Document Type: Article
Times cited : (25)

References (48)
  • 1
    • 0033817601 scopus 로고    scopus 로고
    • The development of conditionally replicative adenovirus for cancer therapy
    • Alemany M, Curiel DT (2000) The development of conditionally replicative adenovirus for cancer therapy. Clin Cancer Res 6:3395-3399
    • (2000) Clin Cancer Res , vol.6 , pp. 3395-3399
    • Alemany, M.1    Curiel, D.T.2
  • 3
    • 0036885116 scopus 로고    scopus 로고
    • Oncolytic viruses
    • Chiocca EA (2002) Oncolytic viruses. Nat Rev Cancer 2:938-950
    • (2002) Nat Rev Cancer , vol.2 , pp. 938-950
    • Chiocca, E.A.1
  • 4
    • 0002093123 scopus 로고    scopus 로고
    • Osteosarcoma
    • Dorfman HD, Czerniak B (eds) 1st edn. Mosby, St. Louis
    • Dorfman HD, Czerniak B (1998) Osteosarcoma. In: Dorfman HD, Czerniak B (eds) Bone tumors, 1st edn. Mosby, St. Louis, pp 128-129
    • (1998) Bone Tumors , pp. 128-129
    • Dorfman, H.D.1    Czerniak, B.2
  • 5
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1beta-converting enzyme
    • Fernandes-Alnemri T, Litwack G, Alnemri ES (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J Biol Chem 269:30761-30764 (Pubitemid 24377553)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.49 , pp. 30761-30764
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 7
    • 33745190090 scopus 로고    scopus 로고
    • Enhanced antitumor efficacy of telomerase-selective oncolytic adenoviral agent OBP-401 with docetaxel: Preclinical evaluation of chemovirotherapy
    • Fujiwara T, Kagawa S, Kishimoto H, Endo Y, Hioki M, Ikeda Y, Sakai R, Urata Y, Tanaka N, Fujiwara T (2006) Enhanced antitumor efficacy of telomerase-selective oncolytic adenoviral agent OBP-401 with docetaxel: preclinical evaluation of chemovirotherapy. Int J Cancer 119:432-440
    • (2006) Int J Cancer , vol.119 , pp. 432-440
    • Fujiwara, T.1    Kagawa, S.2    Kishimoto, H.3    Endo, Y.4    Hioki, M.5    Ikeda, Y.6    Sakai, R.7    Urata, Y.8    Tanaka, N.9    Fujiwara, T.10
  • 8
    • 67549146091 scopus 로고    scopus 로고
    • Phase I trial of intratumoral administration of OBP-301, a novel telomerase-specific oncolytic virus in patients with advanced solid cancer: Evaluation of biodistribution and immune response
    • Fujiwara T, Tanaka N, Nemunaitis JJ, Senzer NN, Tong A, Ichimaru D, Shelby SM, Hashimoto Y, Kawamura H, Urata Y (2008) Phase I trial of intratumoral administration of OBP-301, a novel telomerase-specific oncolytic virus in patients with advanced solid cancer: evaluation of biodistribution and immune response. J Clin Oncol 26:171s
    • (2008) J Clin Oncol , vol.26
    • Fujiwara, T.1    Tanaka, N.2    Nemunaitis, J.J.3    Senzer, N.N.4    Tong, A.5    Ichimaru, D.6    Shelby, S.M.7    Hashimoto, Y.8    Kawamura, H.9    Urata, Y.10
  • 11
    • 0033022039 scopus 로고    scopus 로고
    • p53-independent and -dependent requirements for E1B-55K in adenovirus type 5 replication
    • Harada JN, Berk AJ (1999) p53-independent and -dependent requirements for E1B-55 k in adenovirus type 5 replication. J. Virol 73:5333-5344 (Pubitemid 29274815)
    • (1999) Journal of Virology , vol.73 , Issue.7 , pp. 5333-5344
    • Harada, J.N.1    Berk, A.J.2
  • 13
    • 0025769025 scopus 로고
    • Redundant elements in the adenovirus type 5 inverted terminal repeat promote bidirectional transcription in vitro and are important for virus growth in vivo
    • Hatfield L, Hearing P (1991) Redundant elements in the adenovirus type 5 inverted terminal repeat promote bidirectional transcription in vitro and are important for virus growth in vivo. Virology 184:265-276
    • (1991) Virology , vol.184 , pp. 265-276
    • Hatfield, L.1    Hearing, P.2
  • 15
    • 42549129252 scopus 로고    scopus 로고
    • Combination of oncolytic adenovirotherapy and Bax gene therapy in human cancer xenografted models. Potential merits and hurdles for combination therapy
    • DOI 10.1002/ijc.23438
    • Hioki M, Kagawa S, Fujiwara T, Sakai R, Kojima T, Watanabe Y, Hashimoto Y, Uno F, Tanaka N, Fujiwara T (2008) Combination of oncolytic adenovirotherapy and Bax gene therapy in human cancer xenografted models. Potential merits and hurdles for combination therapy. Int J Cancer 122:2628-2633 (Pubitemid 351590501)
    • (2008) International Journal of Cancer , vol.122 , Issue.11 , pp. 2628-2633
    • Hioki, M.1    Kagawa, S.2    Fujiwara, T.3    Sakai, R.4    Kojima, T.5    Watanabe, Y.6    Hashimoto, Y.7    Uno, F.8    Tanaka, N.9    Fujiwara, T.10
  • 17
    • 0026563921 scopus 로고
    • Three human osteosarcoma cell lines exhibiting different phenotypic expressions
    • Hotta T, Motoyama T, Watanabe H (1992) Three human osteosarcoma cell lines exhibiting different phenotypic expressions. Acta Pathol Jpn 42:595-603
    • (1992) Acta Pathol Jpn , vol.42 , pp. 595-603
    • Hotta, T.1    Motoyama, T.2    Watanabe, H.3
  • 18
    • 1442348829 scopus 로고    scopus 로고
    • Conditionally replicative adenovirus driven by the human telomerase promoter provides broad-spectrum antitumor activity without liver toxicity
    • DOI 10.1038/sj.cgt.7700666
    • Irving J, Wang Z, Powell S, O'Sullivan C, Mok M, Murphy B, Cardoza L, Lebkowski JS, Majumdar AS (2004) Conditionally replicative adenovirus driven by the human telomerase promoter provides broad-spectrum antitumor activity without liver toxicity. Cancer Gene Ther 11:174-185 (Pubitemid 38280520)
    • (2004) Cancer Gene Therapy , vol.11 , Issue.3 , pp. 174-185
    • Irving, J.1    Wang, Z.2    Powell, S.3    O'Sullivan, C.4    Mok, M.5    Murphy, B.6    Cardoza, L.7    Lebkowski, J.S.8    Majumdar, A.S.9
  • 22
    • 0035134629 scopus 로고    scopus 로고
    • Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: What have we learned?
    • Kirn D (2001) Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned? Gene Ther 8:89-98
    • (2001) Gene Ther , vol.8 , pp. 89-98
    • Kirn, D.1
  • 23
    • 0034927057 scopus 로고    scopus 로고
    • Replication-selective virotherapy for cancer: Biological principles, risk management and future directions
    • DOI 10.1038/89901
    • Kirn D, Martuza RL, Zwiebel J (2001) Replication-selective virotherapy for cancer: biological principles, risk management and future directions. Nat Med 7:781-787 (Pubitemid 32691631)
    • (2001) Nature Medicine , vol.7 , Issue.7 , pp. 781-787
    • Kirn, D.1    Martuza, R.L.2    Zwiebel, J.3
  • 25
    • 0032498630 scopus 로고    scopus 로고
    • E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by zVAD-fmk
    • DOI 10.1083/jcb.140.3.637
    • Lavoie JN, Nguyen M, Marcellus RC, Branton PE, Shore GC (1998) E4orf4, a novel adenovirus death factor that induces p53-independent apoptosis by a pathway that is not inhibited by zVAD-fmk. J Cell Biol 140:637-645 (Pubitemid 28134066)
    • (1998) Journal of Cell Biology , vol.140 , Issue.3 , pp. 637-645
    • Lavoie, J.N.1    Nguyen, M.2    Marcellus, R.C.3    Branton, P.E.4    Shore, G.C.5
  • 26
    • 0024456615 scopus 로고
    • The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism
    • Leppard KN, Shenk T (1989) The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism. EMBO J 8:2329-2336 (Pubitemid 19273312)
    • (1989) EMBO Journal , vol.8 , Issue.8 , pp. 2329-2336
    • Leppard, K.N.1    Shenk, T.2
  • 27
    • 33846981552 scopus 로고    scopus 로고
    • Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: A randomized phase III trial of the European Osteosarcoma intergroup
    • MRC, MRC BO06 and EORTC 80931 collaborators; European Osteosarcoma Intergroup
    • Lewis IJ, Nooij MA, Whelan J, Sydes MR, Grimer R, Hogendoorn PC, Memon MA, Weeden S, Uscinska BM, van Glabbeke M, Kirkpatrick A, Hauben EI, Craft AW, Taminiau AH MRC, MRC BO06 and EORTC 80931 collaborators; European Osteosarcoma Intergroup (2007) Improvement in histologic response but not survival in osteosarcoma patients treated with intensified chemotherapy: a randomized phase III trial of the European Osteosarcoma intergroup. J Natl Cancer Inst 99:112-128
    • (2007) J Natl Cancer Inst , vol.99 , pp. 112-128
    • Lewis, I.J.1    Nooij, M.A.2    Whelan, J.3    Sydes, M.R.4    Grimer, R.5    Hogendoorn, P.C.6    Memon, Ma.7    Weeden, S.8    Uscinska, B.M.9    Van Glabbeke, M.10    Kirkpatrick, A.11    Hauben, E.I.12    Craft, A.W.13    Taminiau, A.H.14
  • 28
    • 65749087841 scopus 로고    scopus 로고
    • Cytogenetic and real-time quantitative reverse-transcriptase polymerase chain reaction analyses in pleomorphic rhabdomyosarcoma
    • Li G, Ogose A, Kawashima H, Umezu H, Hotta T, Tohyama T, Ariizumi T, Endo N (2009) Cytogenetic and real-time quantitative reverse-transcriptase polymerase chain reaction analyses in pleomorphic rhabdomyosarcoma. Cancer Genet Cytogent 192:1-9
    • (2009) Cancer Genet Cytogent , vol.192 , pp. 1-9
    • Li, G.1    Ogose, A.2    Kawashima, H.3    Umezu, H.4    Hotta, T.5    Tohyama, T.6    Ariizumi, T.7    Endo, N.8
  • 30
  • 31
    • 0020700258 scopus 로고
    • Far upstream initiation sites for adenovirus early region 1A transcription are utilized after the onset of viral DNA replication
    • Osborne TF, Berk AJ (1983) Far upstream initiation sites for adenovirus early region 1A transcription are utilized after the onset of viral DNA replication. J Virol 45:594-599 (Pubitemid 13225424)
    • (1983) Journal of Virology , vol.45 , Issue.2 , pp. 594-599
    • Osborne, T.F.1    Berk, A.J.2
  • 32
    • 0030739355 scopus 로고    scopus 로고
    • Induction of DNA synthesis and apoptosis are separable functions of E2F- 1
    • Phillips AC, Bates S, Ryan KM, Helin K, Vousden KH (1997) Induction of DNA synthesis and apoptosis are separable functions of E2F-1. Genes Dev 11:1853-1863 (Pubitemid 27315214)
    • (1997) Genes and Development , vol.11 , Issue.14 , pp. 1853-1863
    • Phillips, A.C.1    Bates, S.2    Ryan, K.M.3    Helin, K.4    Vousden, K.H.5
  • 33
    • 0030790684 scopus 로고    scopus 로고
    • Prostate attenuated replication competent adenovirus (ARCA) CN706: A selective cytotoxic for prostate-specific antigen-positive prostate cancer cells
    • Rodriguez R, Schuur ER, Lim HY, Henderson GA, Simons JW, Henderson DR (1997) Prostate attenuated replication competent adenovirus (ARCA) CN706: a selective cytotoxic for prostate-specific antigen-positive prostate cancer cells. Cancer Res 57:2559-2563 (Pubitemid 27283756)
    • (1997) Cancer Research , vol.57 , Issue.13 , pp. 2559-2563
    • Rodriguez, R.1    Schuur, E.R.2    Lim, H.Y.3    Henderson, G.A.4    Simons, J.W.5    Henderson, D.R.6
  • 35
    • 0031010342 scopus 로고    scopus 로고
    • A survey of telomerase activity in human cancer
    • Shay JW, Bacchetti S (1997) A survey of telomerase activity in human cancer. Eur J Cancer 33:787-791
    • (1997) Eur J Cancer , vol.33 , pp. 787-791
    • Shay, J.W.1    Bacchetti, S.2
  • 37
    • 1642555901 scopus 로고    scopus 로고
    • Telomerase activity and telomere length in primary and metastatic tumors from pediatric bone cancer patients
    • Sotillo-Piñeiro E, Sierrasesúmaga L, Patiñno- García A (2004) Telomerase activity and telomere length in primary and metastatic tumors from pediatric bone cancer patients. Pediatr Res 55:231-235
    • (2004) Pediatr Res , vol.55 , pp. 231-235
    • Sotillo-Piñeiro, E.1    Sierrasesúmaga, L.2    Patiñno- García, A.3
  • 38
    • 0033082526 scopus 로고    scopus 로고
    • Cloning of human telomerase catalytic subunit (hTERT) gene for transcriptional activation in immortalized and cancer cells
    • Takakura M, Kyo S, Kanaya T, Hirano H, Takeda J, Yutsudo M, Inoue M (1999) Cloning of human telomerase catalytic subunit (hTERT) gene for transcriptional activation in immortalized and cancer cells. Cancer Res 59:551-557
    • (1999) Cancer Res , vol.59 , pp. 551-557
    • Takakura, M.1    Kyo, S.2    Kanaya, T.3    Hirano, H.4    Takeda, J.5    Yutsudo, M.6    Inoue, M.7
  • 39
    • 72449124142 scopus 로고    scopus 로고
    • Intraperitoneal administration of telomerase-specific oncolytic adenovirus sensitizes ovarian cancer cells to cisplatin and affects survival in a xenograft model with peritoneal dissemination
    • Takakura M, Nakamura M, Kyo S, Hashimoto M, Mori N, Ikoma T, Mizumoto Y, Fujiwara T, Urata Y, Inoue M (2010) Intraperitoneal administration of telomerase-specific oncolytic adenovirus sensitizes ovarian cancer cells to cisplatin and affects survival in a xenograft model with peritoneal dissemination. Cancer Gene Ther 17:11-19
    • (2010) Cancer Gene Ther , vol.17 , pp. 11-19
    • Takakura, M.1    Nakamura, M.2    Kyo, S.3    Hashimoto, M.4    Mori, N.5    Ikoma, T.6    Mizumoto, Y.7    Fujiwara, T.8    Urata, Y.9    Inoue, M.10
  • 40
    • 21044457510 scopus 로고    scopus 로고
    • Enhanced oncolysis by a tropism-modified telomerase-specific replication-selective adenoviral agent OBP-405 ('Telomelysin-RGD')
    • DOI 10.1038/sj.onc.1208460
    • Taki M, Kagawa S, Nishizaki M, Mizuguchi H, Hayakawa T, Kyo S, Nagai K, Urata Y, Tanaka N, Fujiwara T (2005) Enhanced oncolysis by a tropism-modified telomerase-specific replication-selective adenoviral agent OBP-405 ('Telomelysin-RGD'). Oncogene 24:3130-3140 (Pubitemid 40695082)
    • (2005) Oncogene , vol.24 , Issue.19 , pp. 3130-3140
    • Taki, M.1    Kagawa, S.2    Nishizaki, M.3    Mizuguchi, H.4    Hayakawa, T.5    Kyo, S.6    Nagai, K.7    Urata, Y.8    Tanaka, N.9    Fujiwara, T.10
  • 41
    • 0037096881 scopus 로고    scopus 로고
    • An E2F-responsive replication-selective adenovirus targeted to the defective cell cycle in cancer cells: Potent antitumoral efficacy but no toxicity to normal cell
    • Tsukuda K, Wiewrodt R, Molnar-Kimber K, Jovanovic VP, Amin KM (2002) An E2F-responsive replication-selective adenovirus targeted to the defective cell cycle in cancer cells: potent antitumoral efficacy but no toxicity to normal cell. Cancer Res 62:3438-3447 (Pubitemid 34651390)
    • (2002) Cancer Research , vol.62 , Issue.12 , pp. 3438-3447
    • Tsukuda, K.1    Wiewrodt, R.2    Molnar-Kimber, K.3    Jovanovic, V.P.4    Amin, K.M.5
  • 43
    • 4344706615 scopus 로고    scopus 로고
    • Visualization of intrathoracically disseminated solid tumors in mice with optical imaging by telomerase-specific amplification of a transferred green fluorescent protein gene
    • DOI 10.1158/0008-5472.CAN-04-1335
    • Umeoka T, Kawashima T, Kagawa S, Teraishi F, Taki M, Nishizaki M, Kyo S, Nagai K, Urata Y, Tanaka N, Fujiwara T (2004) Visualization of intrathoracically disseminated solid tumors in mice with optical imaging by telomerase-specific amplification of a transferred green fluorescent protein gene. Cancer Res 64:6259-6265 (Pubitemid 39129429)
    • (2004) Cancer Research , vol.64 , Issue.17 , pp. 6259-6265
    • Umeoka, T.1    Kawashima, T.2    Kagawa, S.3    Teraishi, F.4    Taki, M.5    Nishizaki, M.6    Kyo, S.7    Nagai, K.8    Urata, Y.9    Tanaka, N.10    Fujiwara, T.11
  • 44
    • 29144485434 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor FR901228 enhances the antitumor effect of telomerase-specific replication-selective adenoviral agent OBP-301 in human lung cancer cells
    • DOI 10.1016/j.yexcr.2005.10.026, PII S0014482705004829
    • Watanabe T, Hioki M, Fujiwara T, Nishizaki M, Kagawa S, Taki M, Kishimoto H, Endo Y, Urata Y, Tanaka N, Fujiwara T (2006) Histone deacetylase inhibitor FR901228 enhances the antitumor effect of telomerase-specific replication-selective adenoviral agent OBP-301 in human lung cancer cells. Exp Cell Res 312:256-265 (Pubitemid 41814835)
    • (2006) Experimental Cell Research , vol.312 , Issue.3 , pp. 256-265
    • Watanabe, T.1    Hioki, M.2    Fujiwara, T.3    Nishizaki, M.4    Kagawa, S.5    Taki, M.6    Kishimoto, H.7    Endo, Y.8    Urata, Y.9    Tanaka, N.10    Fujiwara, T.11
  • 46
    • 0026560315 scopus 로고
    • Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein
    • Yew PR, Berk AJ (1992) Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein. Nature 357:82-85
    • (1992) Nature , vol.357 , pp. 82-85
    • Yew, P.R.1    Berk, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.