Antihyperalgesic effects induced by the IL-1 receptor antagonist anakinra and increased IL-1β levels in inflamed and osteosarcoma-bearing mice

Life Sciences

Volumn 81, Issue 8, 2007, Pages 673-682

  Baamonde, Ana ^a   Curto Reyes, Verdad ^a   Juárez, Lucía ^a   Meana, Álvaro ^b   Hidalgo, Agustín ^a   Menéndez, Luis ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^b Centro Comunitario de Sangre y Tejidos del Principado de Asturias   (Spain)

Author keywords

Allodynia; Anakinra; Hyperalgesia; IL 1 ; IL 1ra; Inflammation; Mouse; Osteosarcoma; Pain

Indexed keywords

FREUND ADJUVANT; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PAIN; CHRONIC INFLAMMATION; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG SCREENING; HYPERALGESIA; MECHANICAL STIMULATION; MOUSE; NONHUMAN; OSTEOSARCOMA; SPINAL CORD; THERMAL STIMULATION; TIBIA;

ANIMALS; BEHAVIOR, ANIMAL; BONE NEOPLASMS; CELLS, CULTURED; DINOPROSTONE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FREUND'S ADJUVANT; HYPERALGESIA; INFLAMMATION; INJECTIONS, SPINAL; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; MICE; MICE, INBRED C3H; OSTEOSARCOMA; PAIN MEASUREMENT; PHYSICAL STIMULATION; PRESSURE; RECEPTORS, INTERLEUKIN-1; SPINAL CORD;

MURINAE; MUS;

EID: 34547946896     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.07.003     Document Type: Article

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