Kaposi's sarcoma tumor cells preferentially express Bcl-x(L)

American Journal of Pathology

Volumn 149, Issue 3, 1996, Pages 795-803

  Foreman, Kimberly E ^a,b   Wrone Smith, Tamara ^a   Boise, Lawrence H ^c   Thompson, Craig B ^c   Polverini, Peter J ^d   Simonian, Philip L ^a   Nunez, Gabriel ^a   Nickoloff, Brian J ^a,b,e  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 2;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CELL DEATH; CLINICAL ARTICLE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOHISTOCHEMISTRY; KAPOSI SARCOMA; PRIORITY JOURNAL; PSORIASIS; PYOGENIC GRANULOMA;

BCL-X PROTEIN; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; FLOW CYTOMETRY; GRANULOMA, PYOGENIC; GTP-BINDING PROTEINS; HUMANS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PSORIASIS; SARCOMA, KAPOSI; SKIN NEOPLASMS;

EID: 0029785175     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Folkman J: The role of angiogenesis in tumor growth. Semin Cancer Biol 1992, 3:65-71
2. Re F, Zanetti A, Sironi M, Polentaratti N, Lanfrancone L, Dejana E, Colotta F: Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells. J Cell Biol 1994, 127:537-546
3. 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994, 79:1157-1164
4. Hengartner MO: Programmed cell death: a rich harvest. Curr Biol 1994, 4:950-952
5. Boise LH, Gonzalez-Garcia GM, Postema CE, Diag L, Lindsten T, Turka LA, Mao X, Nunez G, Thompson CB: bcl-x, a bcl-2 related gene that functions as a dominant regulator of apoptotic cell death. Cell 1993, 74:597-608
6. Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1992, 348:334-337
7. Reed JC: Bcl-2 and the regulation of programmed cell death. J Cell Biol 1994, 124:1-6
8. Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 1995, 267:1456-1462
9. Hockenbery DM, Zutter M, Hickey W, Nahm M, Korsmeyer SJ: Bcl-2 protein is topographically restricted in tissues characterized by apoptotic cell death. Proc Natl Acad Sci USA 1991, 88:6961-6965
10. Krajewski S, Krajewska M, Shabaik A, Wang HG, Irie S, Fong L, Reed JC: Immunohistochemical analysis of in vivo patterns of Bcl-x expression. Cancer Res 1994, 54:5501-5507
11. Krajewski S, Krajewska M, Shabaik A, Miyahita HT, Wang HG, Reed JC: Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2. Am J Pathol 1994, 145:1323-1333
12. Haake AR, Polakowska RR: Cell death by apoptosis in epidermal biology. J Invest Dermatol 1993, 101:107-112
13. Lu Q-L, Poulsom R, Wong L, Hanby AM: Bcl-2 expression in adult and embryonic non-hematopoietic tissues. J Pathol 1993, 169:431-437
14. Folkman J: Angiogenesis in psoriasis: therapeutic implications. J Invest Dermatol 1972, 59:40-43
15. Wrone-Smith T, Johnson T, Nelson B, Boise LH, Thompson CB, Nunez G, Nickoloff BJ: Discordant expression of Bcl-x and Bcl-2 by keratinocytes in vitro and psoriatic keratinocytes in vivo. Am J Pathol 1995, 146: 1079-1088
16. Rutgers JF, Wieczorek R, Bonetti F, Kaplan KE, Posenett DN, Friedman-Kien AE, Knowles DM: The expression of endothelial cell surface antigen by AIDS-associated Kaposi's sarcoma: evidence for a vascular endothelial cell origin. Am J Pathol 1986, 122:493-499
17. Naidu M, Rosen EM, Zitnick R, Goldberg I, Park M, Naujokas M, Polverini PJ, Nickoloff BJ: Role of scatter factor in the pathogenesis of AIDS-related Kaposi's sarcoma. Proc Natl Acad Sci USA 1994, 91:5281-5285
18. Huang YQ, Friedman-Kien AE, Li JJ, Nickoloff BJ: Cultured Kaposi's sarcoma cell lines express factor XIIIa, CD14, and VCAM-1, but not factor VIII or ELAM-1. Arch Dermatol 1993, 129:1291-1296
19. Brooks JJ: Kaposi's sarcoma: a reversible hyperplasia. Lancet 1986, 2:1309-1311
20. Costa J, Rabson AS: Generalized Kaposi s sarcoma is not a neoplasm. Lancet 1983, 1:58
21. Ensoli B, Barillari G, Gallo RC: Pathogenesis of AIDS-associated Kaposi's sarcoma. Hematol Oncol Clin North Am 1995, 5:281-295
22. Jaffe EA: Culture and identification of large vessel endothelial cells. Biology of Endothelial Cells. Edited by EA Jaffe. The Hague, Martinus Nijoff, 1984, pp 1-13
23. Nickoloff BJ, Karabin GD, Barker JN, Griffiths CEM, Sarma V, Mitra RS, Kunkel SL, Dixit V: Cellular localization of interleukin-8 and its inducer tumor necrosis factor-α in psoriasis. Am J Pathol 1991, 138:129-140
24. Gottschalk AR, Boise LH, Thompson CB, Quintans J: Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2. Proc Natl Acad Sci USA 1994, 91:7350-7354
25. Mansbridge JN, Nickoloff BJ, Morhenn VB: Induction of new proteins by γ-interferon in cultured human keratinocytes. J Invest Dermatol 1987, 88:602-610
26. L is the major bcl-x mRNA expressed during murine development and its product localizes to mitochondria. Development 1994, 120:3033-3042
27. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-686
28. Modlin RL, Hoffman FM, Meyer PR, Vaccaro SA, Ammann AJ, Conant MA, Rea TH, Taylor CR: Altered distribution of B and T lymphocytes in lymph nodes from homosexual men with Kaposi's sarcoma. Lancet 1983, 2:768-771
29. O'Connell KA, Rudmann AA: Cloned spindle and epithelioid cells from murine Kaposi's sarcoma-like tumors are of endothelial origin. J Invest Dermatol 1993, 100: 742-745
30. O'Connell KA, Edidin M: A mouse lymphoid endothelial cell line immortalized by simian virus 40 binds lymphocytes and retains functional characteristics of normal endothelial cells. J Immunol 1990, 144:521-525
31. Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ: Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 1993, 75:229-240
32. Reed JC, Meister L, Tanaka S, Cuddy M, Yum S, Geyer C, Pleasure D: Differential expression of Bcl-2 protooncogene in neuroblastoma and other tumor cell lines of neural origin. Cancer Res 1991, 51:6529-6538
33. Nunez G, Merino R, Grillot D, Gonzalez-Garcia M: Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival, Immunol Today 1994, 15:582-588
34. Joensuu HL, Pylkkanen L, Toikkanen S: Bcl-2 protein expression and long term survival in breast cancer. Am J Pathol 1994, 145:1191-1198
35. L is expressed in neuroblastoma cells and modulate chemotherapy-induced apoptosis. Cancer Res 1995, 55:2576-2582
36. Reiners JJ, Rupp T, Colby A, Cantu AR, Pavone A: Tumor co-promoting activity of γ-interferon in the murine skin multistage carcinogenesis model. Cancer Res 1989, 49:1202-1206
37. Nickoloff BJ, Foreman KE: Charting a new course through the chaos of KS (Kaposi's sarcoma). Am J Pathol 1996, 148:1323-1329