Paeonol oxime inhibits bfGF-induced angiogenesis and reduces VEGF levels in fibrosarcoma cells

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  Lee, Hyo Jeong ^a   Kim, Seung Ae ^a   Lee, Hyo Jung ^a   Jeong, Soo Jin ^a   Han, Ihn ^a   Jung, Ji Hoon ^a   Lee, Eun Ok ^a   Zhu, Shudong ^b   Chen, Chang Yan ^b   Kim, Sung Hoon ^a  

^a Kyung Hee University   (South Korea)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BASIC FIBROBLAST GROWTH FACTOR; PEONOL; PEONOL DERIVATIVE; PEONOL OXIME; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; VASCULOTROPIN; ACETOPHENONE DERIVATIVE; FIBROBLAST GROWTH FACTOR 2; OXIME; PAEONOL OXIME; VASCULOTROPIN A;

ANGIOGENESIS; ARTICLE; CAPILLARY; CELL LINE; CELL MIGRATION; CELL STRAIN HT 1080; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; FIBROSARCOMA; HUMAN; HUMAN CELL; IC 50; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; IN VIVO STUDY; NEOVASCULARIZATION (PATHOLOGY); PROTEIN EXPRESSION; SARCOMA CELL; UMBILICAL VEIN; VASCULAR TUMOR; ANIMAL; CELL DIFFERENTIATION; CELL MOTION; CELL PROLIFERATION; CHEMICALLY INDUCED DISORDER; CHICKEN; CHORIOALLANTOIS; CYTOLOGY; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; VASCULARIZATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETOPHENONES; ANIMALS; CAPILLARIES; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CHICKENS; CHORIOALLANTOIC MEMBRANE; DOWN-REGULATION; ENDOTHELIAL CELLS; FIBROBLAST GROWTH FACTOR 2; FIBROSARCOMA; HUMANS; NEOVASCULARIZATION, PATHOLOGIC; OXIMES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; UMBILICAL VEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77957875746     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012358     Document Type: Article

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