A spatially and temporally restricted mouse model of soft tissue sarcoma

Nature Medicine

Volumn 13, Issue 8, 2007, Pages 992-997

  Kirsch, David G ^a,b,h   Dinulescu, Daniela M ^a,c   Miller, John B ^a   Grimm, Jan ^b,i   Santiago, Philip M ^a   Young, Nathan P ^a   Nielsen, G Petur ^b   Quade, Bradley J ^c   Chaber, Christopher J ^a   Schultz, Christian P ^d   Takeuchi, Osamu ^e   Bronson, Roderick T ^f   Crowley, Denise ^a   Korsmeyer, Stanley J ^e   Yoon, Sam S ^b   Hornicek, Francis J ^b   Weissleder, Ralph ^b   Jacks, Tyler ^a,g  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d SIEMENS CORPORATE RESEARCH   (United States)

^e DANA FARBER CANCER INSTITUTE   (United States)

^f TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^h DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; PROTEIN BAK; PROTEIN BAK 1; PROTEIN BAX; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; GENE DELETION; GENE LOCUS; GENE MUTATION; LUNG METASTASIS; LYMPH NODE METASTASIS; MOLECULAR IMAGING; MOUSE; NONHUMAN; ONCOGENE K RAS; PATHOGENESIS; PRIORITY JOURNAL; SOFT TISSUE SARCOMA; TRP53 GENE;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, NEOPLASTIC; LUNG NEOPLASMS; MICE; MICE, KNOCKOUT; SARCOMA; TIME FACTORS; TUMOR SUPPRESSOR PROTEIN P14ARF; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

ADENOVIRIDAE; MUS;

EID: 34547660321     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1602     Document Type: Article

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