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Volumn 72, Issue 10, 2012, Pages 2501-2511

Phosphoproteomics identifies driver tyrosine kinases in sarcoma cell lines and tumors

Author keywords

[No Author keywords available]

Indexed keywords

3 [4 METHYL 2 (2 OXO 3 INDOLINYLMETHYLIDENYL) 3 PYRROLYL]PROPIONIC ACID; 5 (2,6 DICHLOROBENZYLSULFONYL) 3 [3,5 DIMETHYL 4 [2 (1 PYRROLIDINYLMETHYL) 1 PYRROLIDINYLCARBONYL] 1H PYRROL 2 YLMETHYLENE] 1,3 DIHYDRO 2H INDOL 2 ONE; DASATINIB; ENZYME ANTIBODY; ERLOTINIB; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; IMATINIB; INSULIN RECEPTOR; JANUS KINASE 1; JANUS KINASE 2; JANUS KINASE 3; OSI 868; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN AXL; PROTEIN DDR1; PROTEIN DDR2; PROTEIN EPHB4; PROTEIN FAK; PROTEIN KINASE; PROTEIN KINASE LYN; PROTEIN SRC; PROTEIN TYR2; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SCATTER FACTOR RECEPTOR; SOMATOMEDIN C; SOMATOMEDIN RECEPTOR; UNCLASSIFIED DRUG; VANDETANIB;

EID: 84861158485     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-3015     Document Type: Article
Times cited : (98)

References (36)
  • 3
    • 79952234603 scopus 로고    scopus 로고
    • Receptor tyrosine kinases as therapeutic targets in rhabdomyosarcoma
    • Crose LE, Linardic CM. Receptor tyrosine kinases as therapeutic targets in rhabdomyosarcoma. Sarcoma 2011;2011:756982.
    • (2011) Sarcoma , vol.2011 , pp. 756982
    • Crose, L.E.1    Linardic, C.M.2
  • 4
    • 40749125333 scopus 로고    scopus 로고
    • Therapeutic potential of directed tyrosine kinase inhibitor therapy in sarcomas
    • Shor AC, Agresta SV, D'Amato GZ, Sondak VK. Therapeutic potential of directed tyrosine kinase inhibitor therapy in sarcomas. Cancer Control 2008;15:47-54. (Pubitemid 351481991)
    • (2008) Cancer Control , vol.15 , Issue.1 , pp. 47-54
    • Shor, A.C.1    Agresta, S.V.2    D'Amato, G.Z.3    Sondak, V.K.4
  • 7
    • 33745800293 scopus 로고    scopus 로고
    • Interpreting the protein language using proteomics
    • DOI 10.1038/nrm1939, PII NRM1939
    • Jensen ON. Interpreting the protein language using proteomics. Nat Rev Mol Cell Biol 2006;7:391-403. (Pubitemid 44050093)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.6 , pp. 391-403
    • Jensen, O.N.1
  • 8
    • 0031457622 scopus 로고    scopus 로고
    • Signaling through scaffold, anchoring, and adaptor proteins
    • DOI 10.1126/science.278.5346.2075
    • Pawson T, Scott JD. Signaling through scaffold, anchoring, and adaptor proteins. Science 1997;278:2075-80. (Pubitemid 28028310)
    • (1997) Science , vol.278 , Issue.5346 , pp. 2075-2080
    • Pawson, T.1    Scott, J.D.2
  • 12
    • 77949848665 scopus 로고    scopus 로고
    • A chemical and phosphoproteomic characterization of dasatinib action in lung cancer
    • Li J, Rix U, Fang B, Bai Y, Edwards A, Colinge J, et al. A chemical and phosphoproteomic characterization of dasatinib action in lung cancer. Nat Chem Biol 2010;6:291-9.
    • (2010) Nat Chem Biol , vol.6 , pp. 291-299
    • Li, J.1    Rix, U.2    Fang, B.3    Bai, Y.4    Edwards, A.5    Colinge, J.6
  • 15
    • 84855645086 scopus 로고    scopus 로고
    • MK1775, a selective Wee1 inhibitor, shows single-agent antitumor activity against sarcoma cells
    • Kreahling JM, Gemmer JY, Reed D, Letson D, Bui M, Altiok S. MK1775, a selective Wee1 inhibitor, shows single-agent antitumor activity against sarcoma cells. Mol Cancer Ther 2012;11:174-82.
    • (2012) Mol Cancer Ther , vol.11 , pp. 174-182
    • Kreahling, J.M.1    Gemmer, J.Y.2    Reed, D.3    Letson, D.4    Bui, M.5    Altiok, S.6
  • 16
    • 0037032835 scopus 로고    scopus 로고
    • The protein kinase complement of the human genome
    • DOI 10.1126/science.1075762
    • Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. The protein kinase complement of the human genome. Science 2002;298:1912-34. (Pubitemid 35425239)
    • (2002) Science , vol.298 , Issue.5600 , pp. 1912-1934
    • Manning, G.1    Whyte, D.B.2    Martinez, R.3    Hunter, T.4    Sudarsanam, S.5
  • 20
    • 42049123098 scopus 로고    scopus 로고
    • Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib
    • DOI 10.1080/10428190801896103, PII 791364886
    • Hantschel O, Rix U, Superti-Furga G. Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib. Leuk Lymphoma 2008; 49:615-9. (Pubitemid 351517198)
    • (2008) Leukemia and Lymphoma , vol.49 , Issue.4 , pp. 615-619
    • Hantschel, O.1    Rix, U.2    Superti-Furga, G.3
  • 21
    • 77949848665 scopus 로고    scopus 로고
    • A chemical and phosphoproteomic characterization of dasatinib action in lung cancer
    • Li J, Rix U, Fang B, Bai Y, Edwards A, Colinge J, et al. A chemical and phosphoproteomic characterization of dasatinib action in lung cancer. Nat Chem Biol 2010;6:291-9.
    • (2010) Nat Chem Biol , vol.6 , pp. 291-299
    • Li, J.1    Rix, U.2    Fang, B.3    Bai, Y.4    Edwards, A.5    Colinge, J.6
  • 22
    • 62549166213 scopus 로고    scopus 로고
    • Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells
    • Remsing Rix LL, Rix U, Colinge J, Hantschel O, Bennett KL, Stranzl T, et al. Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells. Leukemia 2009;23:477-85.
    • (2009) Leukemia , vol.23 , pp. 477-485
    • Remsing Rix, L.L.1    Rix, U.2    Colinge, J.3    Hantschel, O.4    Bennett, K.L.5    Stranzl, T.6
  • 24
    • 65949104526 scopus 로고    scopus 로고
    • Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors
    • McDermott U, Ames RY, Iafrate AJ, Maheswaran S, Stubbs H, Greninger P, et al. Ligand-dependent platelet-derived growth factor receptor (PDGFR)-alpha activation sensitizes rare lung cancer and sarcoma cells to PDGFR kinase inhibitors. Cancer Res 2009;69: 3937-46.
    • (2009) Cancer Res , vol.69 , pp. 3937-3946
    • McDermott, U.1    Ames, R.Y.2    Iafrate, A.J.3    Maheswaran, S.4    Stubbs, H.5    Greninger, P.6
  • 27
    • 0022472582 scopus 로고
    • Mechanism of met oncogene activation
    • Park M, Dean M, Cooper CS, Schmidt M, O'Brien SJ, Blair DG, et al. Mechanism of met oncogene activation. Cell 1986;45:895-904. (Pubitemid 16083694)
    • (1986) Cell , vol.45 , Issue.6 , pp. 895-904
    • Park, M.1    Dean, M.2    Cooper, C.S.3
  • 28
  • 29
    • 77958067823 scopus 로고    scopus 로고
    • Compensatory insulin receptor (IR) activation on inhibition of insulinlike growth factor-1 receptor (IGF-1R): Rationale for cotargeting IGF-1R and IR in cancer
    • Buck E, Gokhale PC, Koujak S, Brown E, Eyzaguirre A, Tao N, et al. Compensatory insulin receptor (IR) activation on inhibition of insulinlike growth factor-1 receptor (IGF-1R): rationale for cotargeting IGF-1R and IR in cancer. Mol Cancer Ther 2010;9:2652-64.
    • (2010) Mol Cancer Ther , vol.9 , pp. 2652-2664
    • Buck, E.1    Gokhale, P.C.2    Koujak, S.3    Brown, E.4    Eyzaguirre, A.5    Tao, N.6
  • 30
    • 79959265311 scopus 로고    scopus 로고
    • Targeting the insulin-like growth factor 1 receptor in Ewing's Sarcoma: Reality and expectations
    • Olmos D, Martins AS, Jones RL, Alam S, Scurr M, Judson IR. Targeting the insulin-like growth factor 1 receptor in Ewing's Sarcoma: reality and expectations. Sarcoma 2011;2011:402508.
    • (2011) Sarcoma , vol.2011 , pp. 402508
    • Olmos, D.1    Martins, A.S.2    Jones, R.L.3    Alam, S.4    Scurr, M.5    Judson, I.R.6
  • 31
    • 80053062871 scopus 로고    scopus 로고
    • Preliminary efficacy of the anti-insulin-like growth factor type 1 receptor antibody figitumumab in patients with refractory Ewing sarcoma
    • Juergens H, Daw NC, Geoerger B, Ferrari S, Villarroel M, Aerts I, et al. Preliminary efficacy of the anti-insulin-like growth factor type 1 receptor antibody figitumumab in patients with refractory Ewing sarcoma. J Clin Oncol 2011;29:4534-40.
    • (2011) J Clin Oncol , vol.29 , pp. 4534-4540
    • Juergens, H.1    Daw, N.C.2    Geoerger, B.3    Ferrari, S.4    Villarroel, M.5    Aerts, I.6
  • 32
    • 83255163333 scopus 로고    scopus 로고
    • R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: Results of a phase II Sarcoma Alliance for Research through Collaboration study
    • Pappo AS, Patel SR, Crowley J, Reinke DK, Kuenkele KP, Chawla SP, et al. R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: results of a phase II Sarcoma Alliance for Research through Collaboration study. J Clin Oncol 2011;29:4541-7.
    • (2011) J Clin Oncol , vol.29 , pp. 4541-4547
    • Pappo, A.S.1    Patel, S.R.2    Crowley, J.3    Reinke, D.K.4    Kuenkele, K.P.5    Chawla, S.P.6
  • 33
    • 75849125610 scopus 로고    scopus 로고
    • Quantifying oncogenic phosphotyrosine signaling networks through systems biology
    • Del Rosario AM, White FM. Quantifying oncogenic phosphotyrosine signaling networks through systems biology. Curr Opin Genet Dev 2010;20:23-30.
    • (2010) Curr Opin Genet Dev , vol.20 , pp. 23-30
    • Del Rosario, A.M.1    White, F.M.2
  • 34
    • 33744493376 scopus 로고    scopus 로고
    • Targeting tyrosine kinases in cancer: The second wave
    • DOI 10.1126/science.1125951
    • Baselga J. Targeting tyrosine kinases in cancer: the second wave. Science 2006;312:1175-8. (Pubitemid 43801135)
    • (2006) Science , vol.312 , Issue.5777 , pp. 1175-1178
    • Baselga, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.