Blockade of VEGF-A suppresses tumor growth via inhibition of autocrine signaling through FAK and AKT

Cancer Letters

Volumn 318, Issue 2, 2012, Pages 221-225

  Lee, Jungwhoi ^a   Ku, Taeyun ^a   Yu, Hana ^a   Chong, Kyuha ^a   Ryu, Seung Wook ^a   Choi, Kyungsun ^a   Choi, Chulhee ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

AKT; Apoptosis; Autocrine signaling; FAK; VEGF

Indexed keywords

DOXYCYCLINE; FOCAL ADHESION KINASE; PROTEIN KINASE B; VASCULOTROPIN A; VASCULOTROPIN ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASTROCYTOMA; AUTOCRINE EFFECT; CANCER INHIBITION; CELL VIABILITY; DOSE RESPONSE; ENZYME INHIBITION; FIBROSARCOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; ASTROCYTOMA; BASE SEQUENCE; CELL LINE, TUMOR; FIBROSARCOMA; FOCAL ADHESION PROTEIN-TYROSINE KINASES; MICE; MICE, INBRED BALB C; MICE, NUDE; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MURINAE;

EID: 84858158912     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.12.014     Document Type: Article

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