-
1
-
-
75949083202
-
Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates
-
PMID:19725834
-
Martinez A, Portero-Otin M, Pamplona R, Ferrer I. Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates. Brain Pathol 2010; 20:281-97;PMID:19725834; http://dx.doi.org/10.1111/j.1750-3639.2009.00326.x.
-
(2010)
Brain Pathol
, vol.20
, pp. 281-297
-
-
Martinez, A.1
Portero-Otin, M.2
Pamplona, R.3
Ferrer, I.4
-
2
-
-
84862248517
-
Protein oxidation in Huntington disease
-
PMID:22473822
-
Sorolla MA, Rodriguez-Colman MJ, Vall-llaura N, Tamarit J, Ros J, Cabiscol E. Protein oxidation in Huntington disease. BioFactors 2012; 38:173-85; PMID:22473822; http://dx.doi.org/10.1002/biof.1013.
-
(2012)
Biofactors
, vol.38
, pp. 173-185
-
-
Sorolla, M.A.1
Rodriguez-Colman, M.J.2
Vall-Llaura, N.3
Tamarit, J.4
Ros, J.5
Cabiscol, E.6
-
3
-
-
0025790342
-
Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease
-
PMID:1683703
-
Smith CD, Carney JM, Starke-Reed PE, Oliver CN, Stadtman ER, Floyd RA, Markesbery WR. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Natl Acad Sci U S A 1991; 88:10540-3; PMID:1683703; http://dx.doi.org/10.1073/pnas.88.23.10540.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 10540-10543
-
-
Smith, C.D.1
Carney, J.M.2
Starke-Reed, P.E.3
Oliver, C.N.4
Stadtman, E.R.5
Floyd, R.A.6
Markesbery, W.R.7
-
4
-
-
0036284021
-
Early accumulation of p62 in neurofibrillary tangles in Alzheimer’s disease: Possible role in tangle formation
-
PMID:12060347
-
Kuusisto E, Salminen A, Alafuzoff I. Early accumulation of p62 in neurofibrillary tangles in Alzheimer’s disease: possible role in tangle formation. Neuropathol Appl Neurobiol 2002; 28:228-37;PMID:12060347; http://dx.doi.org/10.1046/j.1365-2990.2002.00394.x.
-
(2002)
Neuropathol Appl Neurobiol
, vol.28
, pp. 228-237
-
-
Kuusisto, E.1
Salminen, A.2
Alafuzoff, I.3
-
5
-
-
0036144410
-
P62 Is a common component of cytoplasmic inclusions in protein aggregation diseases
-
PMID:11786419
-
Zatloukal K, Stumptner C, Fuchsbichler A, Heid H, Schnoelzer M, Kenner L, Kleinert R, Prinz M, Aguzzi A, Denk H. p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases. Am J Pathol 2002; 160:255-63; PMID:11786419; http://dx.doi.org/10.1016/S0002-9440(10)64369-6.
-
(2002)
Am J Pathol
, vol.160
, pp. 255-263
-
-
Zatloukal, K.1
Stumptner, C.2
Fuchsbichler, A.3
Heid, H.4
Schnoelzer, M.5
Kenner, L.6
Kleinert, R.7
Prinz, M.8
Aguzzi, A.9
Denk, H.10
-
6
-
-
4744349602
-
Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions
-
PMID:15379887
-
Nagaoka U, Kim K, Jana NR, Doi H, Maruyama M, Mitsui K, Oyama F, Nukina N. Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions. J Neurochem 2004; 91:57-68; PMID:15379887; http://dx.doi.org/10.1111/j.1471-4159.2004.02692.x.
-
(2004)
J Neurochem
, vol.91
, pp. 57-68
-
-
Nagaoka, U.1
Kim, K.2
Jana, N.R.3
Doi, H.4
Maruyama, M.5
Mitsui, K.6
Oyama, F.7
Nukina, N.8
-
7
-
-
79959208615
-
Age-related macular degeneration (AMD): Alzheimer’s disease in the eye?
-
PMID:21297256
-
Kaarniranta K, Salminen A, Haapasalo A, Soininen H, Hiltunen M. Age-related macular degeneration (AMD): Alzheimer’s disease in the eye? J Alzheimers Dis 2011; 24:615-31; PMID:21297256.
-
(2011)
J Alzheimers Dis
, vol.24
, pp. 615-631
-
-
Kaarniranta, K.1
Salminen, A.2
Haapasalo, A.3
Soininen, H.4
Hiltunen, M.5
-
8
-
-
84880797112
-
Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration
-
PMID:23590900
-
Kaarniranta K, Sinha D, Blasiak J, Kauppinen A, Vereb Z, Salminen A, Boulton ME, Petrovski G. Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration. Autophagy 2013; 9:973-84; PMID:23590900; http://dx.doi.org/10.4161/auto.24546.
-
(2013)
Autophagy
, vol.9
, pp. 973-984
-
-
Kaarniranta, K.1
Sinha, D.2
Blasiak, J.3
Kauppinen, A.4
Vereb, Z.5
Salminen, A.6
Boulton, M.E.7
Petrovski, G.8
-
9
-
-
33751103471
-
Age-related macular degeneration–emerging pathogenetic and therapeutic concepts
-
PMID:17101537
-
Gehrs KM, Anderson DH, Johnson LV, Hageman GS. Age-related macular degeneration–emerging pathogenetic and therapeutic concepts. Ann Med 2006; 38:450-71; PMID:17101537; http://dx.doi.org/10.1080/07853890600946724.
-
(2006)
Ann Med
, vol.38
, pp. 450-471
-
-
Gehrs, K.M.1
Erson, D.H.2
Johnson, L.V.3
Hageman, G.S.4
-
10
-
-
84863726788
-
Consequences of oxidative stress in age-related macular degeneration
-
PMID:22510306
-
Jarrett SG, Boulton ME. Consequences of oxidative stress in age-related macular degeneration. Mol Aspects Med 2012; 33:399-417; PMID:22510306; http://dx.doi.org/10.1016/j.mam.2012.03.009.
-
(2012)
Mol Aspects Med
, vol.33
, pp. 399-417
-
-
Jarrett, S.G.1
Boulton, M.E.2
-
11
-
-
0024378477
-
Cell loss in the aging retina. Relationship to lipofuscin accumulation and macular degeneration
-
PMID:2759786
-
Dorey CK, Wu G, Ebenstein D, Garsd A, Weiter JJ. Cell loss in the aging retina. Relationship to lipofuscin accumulation and macular degeneration. Invest Ophthalmol Vis Sci 1989; 30:1691-9; PMID:2759786.
-
(1989)
Invest Ophthalmol Vis Sci
, vol.30
, pp. 1691-1699
-
-
Dorey, C.K.1
Wu, G.2
Ebenstein, D.3
Garsd, A.4
Weiter, J.J.5
-
12
-
-
0033026846
-
Patterns of increased in vivo fundus autofluorescence in the junctional zone of geographic atrophy of the retinal pigment epithelium associated with age-related macular degeneration
-
Holz FG, Bellmann C, Margaritidis M, Schutt F, Otto TP, Volcker HE. Patterns of increased in vivo fundus autofluorescence in the junctional zone of geographic atrophy of the retinal pigment epithelium associated with age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 1999; 237:145-52; http://dx.doi.org/10.1007/s004170050209.
-
(1999)
Graefes Arch Clin Exp Ophthalmol
, vol.237
, pp. 145-152
-
-
Holz, F.G.1
Bellmann, C.2
Margaritidis, M.3
Schutt, F.4
Otto, T.P.5
Volcker, H.E.6
-
13
-
-
0034800655
-
AREDS report no. 8
-
Age-Related Eye Disease Study Research G. A randomized, placebo-controlled, clinical trial of highdose supplementation with vitamins C and E, b carotene, and zinc for age-related macular degeneration and vision loss, PMID:11594942
-
Age-Related Eye Disease Study Research G. A randomized, placebo-controlled, clinical trial of highdose supplementation with vitamins C and E, b carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol 2001; 119:1417-36; PMID:11594942; http://dx.doi.org/10.1001/archopht.119.10.1417.
-
(2001)
Arch Ophthalmol
, vol.119
, pp. 1417-1436
-
-
-
14
-
-
78651369886
-
Compositional studies of human RPE lipofuscin: Mechanisms of molecular modifications
-
PMID:21182214
-
Murdaugh LS, Mandal S, Dill AE, Dillon J, Simon JD, Gaillard ER. Compositional studies of human RPE lipofuscin: mechanisms of molecular modifications. J Mass Spectrom 2011; 46:90-5;PMID:21182214; http://dx.doi.org/10.1002/jms.1865.
-
(2011)
J Mass Spectrom
, vol.46
, pp. 90-95
-
-
Murdaugh, L.S.1
Mandal, S.2
Dill, A.E.3
Dillon, J.4
Simon, J.D.5
Gaillard, E.R.6
-
15
-
-
0034012166
-
Rusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
-
PMID:10783137
-
Mullins RF, Russell SR, Anderson DH, Hageman GS. rusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease. FASEB J 2000; 14:835-46; PMID:10783137.
-
(2000)
FASEB J
, vol.14
, pp. 835-846
-
-
Mullins, R.F.1
Russell, S.R.2
Erson, D.H.3
Hageman, G.S.4
-
16
-
-
11144258543
-
Drusen proteome analysis: An approach to the etiology of age-related macular degeneration
-
PMID:12391305
-
Crabb JW, Miyagi M, Gu X, Shadrach K, West KA, Sakaguchi H, Kamei M, Hasan A, Yan L, Rayborn ME, et al. Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. Proc Natl Acad Sci U S A 2002; 99:14682-7;PMID:12391305; http://dx.doi.org/10.1073/pnas.222551899.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 14682-14687
-
-
Crabb, J.W.1
Miyagi, M.2
Gu, X.3
Shadrach, K.4
West, K.A.5
Sakaguchi, H.6
Kamei, M.7
Hasan, A.8
Yan, L.9
Rayborn, M.E.10
-
17
-
-
84923829587
-
The proteomics of drusen
-
Crabb JW. The proteomics of drusen. Cold Spring Harb Perspect Med 2014; 4:a017194; PMID:24799364; http://dx.doi.org/10.1101/cshperspect.a017194
-
(2014)
Cold Spring Harb Perspect Med
, vol.4
-
-
Crabb, J.W.1
-
19
-
-
60949098753
-
Heat shock proteins as gatekeepers of proteolytic pathways- Implications for age-related macular degeneration (AMD)
-
PMID:19274853
-
Kaarniranta K, Salminen A, Eskelinen EL, Kopitz J. Heat shock proteins as gatekeepers of proteolytic pathways- Implications for age-related macular degeneration (AMD). Ageing Res Rev 2009; 8:128-39;PMID:19274853; http://dx.doi.org/10.1016/j.arr.2009.01.001.
-
(2009)
Ageing Res Rev
, vol.8
, pp. 128-139
-
-
Kaarniranta, K.1
Salminen, A.2
Eskelinen, E.L.3
Kopitz, J.4
-
20
-
-
84863722159
-
How does the macula protect itself from oxidative stress?
-
PMID:22503691
-
Handa JT. How does the macula protect itself from oxidative stress? Mol Aspects Med 2012; 33:418-35;PMID:22503691; http://dx.doi.org/10.1016/j.mam.2012.03.006.
-
(2012)
Mol Aspects Med
, vol.33
, pp. 418-435
-
-
Handa, J.T.1
-
21
-
-
50649116818
-
Misfolded proteins partition between two distinct quality control compartments
-
PMID:18756251
-
Kaganovich D, Kopito R, Frydman J. Misfolded proteins partition between two distinct quality control compartments. Nature 2008; 454:1088-95;PMID:18756251; http://dx.doi.org/10.1038/nature07195.
-
(2008)
Nature
, vol.454
, pp. 1088-1095
-
-
Kaganovich, D.1
Kopito, R.2
Frydman, J.3
-
22
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
PMID:15483602
-
Arrasate M, Mitra S, Schweitzer ES, Segal MR, Finkbeiner S. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature 2004; 431:805-10; PMID:15483602; http://dx.doi.org/10.1038/nature02998.
-
(2004)
Nature
, vol.431
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
Schweitzer, E.S.3
Segal, M.R.4
Finkbeiner, S.5
-
23
-
-
84886952788
-
Protein oxidation in aging and the removal of oxidized proteins
-
PMID:23333925
-
Heohn A, Keonig J, Grune T. Protein oxidation in aging and the removal of oxidized proteins. J Proteomics 2013; 92:132-59; PMID:23333925; http://dx.doi.org/10.1016/j.jprot.2013.01.004.
-
(2013)
J Proteomics
, vol.92
, pp. 132-159
-
-
Heohn, A.1
Keonig, J.2
Grune, T.3
-
24
-
-
34848886914
-
Autophagosome formation: Core machinery and adaptations
-
PMID:17909521
-
Xie Z, Klionsky DJ. Autophagosome formation: core machinery and adaptations. Nat Cell Biol 2007; 9:1102-9; PMID:17909521; http://dx.doi.org/10.1038/ncb1007-1102.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1102-1109
-
-
Xie, Z.1
Klionsky, D.J.2
-
25
-
-
33846189759
-
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-b, and Bcl 2
-
PMID:17244528
-
Hoyer-Hansen M, Bastholm L, Szyniarowski P, Campanella M, Szabadkai G, Farkas T, Bianchi K, Fehrenbacher N, Elling F, Rizzuto R, et al. Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-b, and Bcl 2. Mol Cell 2007; 25:193-205; PMID:17244528; http://dx.doi.org/10.1016/j.molcel.2006.12.009.
-
(2007)
Mol Cell
, vol.25
, pp. 193-205
-
-
Hoyer-Hansen, M.1
Bastholm, L.2
Szyniarowski, P.3
Campanella, M.4
Szabadkai, G.5
Farkas, T.6
Bianchi, K.7
Fehrenbacher, N.8
Elling, F.9
Rizzuto, R.10
-
26
-
-
34247186472
-
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
-
PMID:17347651
-
Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J 2007; 26:1749-60; PMID:17347651; http://dx.doi.org/10.1038/sj.emboj.7601623.
-
(2007)
EMBO J
, vol.26
, pp. 1749-1760
-
-
Scherz-Shouval, R.1
Shvets, E.2
Fass, E.3
Shorer, H.4
Gil, L.5
Elazar, Z.6
-
27
-
-
79959415069
-
Biogenesis and cargo selectivity of autophagosomes
-
PMID:21548784
-
Weidberg H, Shvets E, Elazar Z. Biogenesis and cargo selectivity of autophagosomes. Ann Rev Biochem 2011; 80:125-56; PMID:21548784; http://dx.doi.org/10.1146/annurev-biochem-052709-094552.
-
(2011)
Ann Rev Biochem
, vol.80
, pp. 125-156
-
-
Weidberg, H.1
Shvets, E.2
Elazar, Z.3
-
28
-
-
34548259958
-
P62/ SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
PMID:17580304
-
Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Overvatn A, Bjorkoy G, Johansen T. p62/ SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem 2007; 282:24131-45;PMID:17580304; http://dx.doi.org/10.1074/jbc.M702824200.
-
(2007)
J Biol Chem
, vol.282
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.A.5
Outzen, H.6
Overvatn, A.7
Bjorkoy, G.8
Johansen, T.9
-
29
-
-
27944504351
-
Johansen T. P62/ SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtininduced cell death
-
PMID:16286508
-
Bjorkoy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T. p62/ SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtininduced cell death. J Cell Biol 2005; 171:603-14;PMID:16286508; http://dx.doi.org/10.1083/jcb.200507002.
-
(2005)
J Cell Biol
, vol.171
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
Overvatn, A.6
Stenmark, H.7
-
30
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
PMID:16625204
-
Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, Yokoyama M, Mishima K, Saito I, Okano H, et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 2006; 441:885-9; PMID:16625204; http://dx.doi.org/10.1038/nature04724.
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
Yokoyama, M.7
Mishima, K.8
Saito, I.9
Okano, H.10
-
31
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
PMID:16625205
-
Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, Tanida I, Ueno T, Koike M, Uchiyama Y, Kominami E, et al. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006; 441:880-4; PMID:16625205; http://dx.doi.org/10.1038/nature04723.
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
Tanida, I.6
Ueno, T.7
Koike, M.8
Uchiyama, Y.9
Kominami, E.10
-
32
-
-
84905497318
-
Autophagy is required for glucose homeostasis and lung tumor maintenance
-
PMID:24875857
-
Karsli-Uzunbas G, Guo JY, Price S, Teng X, Laddha SV, Khor S, Kalaany NY, Jacks T, Chan CS, Rabinowitz JD, et al. Autophagy is required for glucose homeostasis and lung tumor maintenance. Cancer Discov 2014; 4:914-27; PMID:24875857; http://dx.doi.org/10.1158/2159-8290.CD-14-0363.
-
(2014)
Cancer Discov
, vol.4
, pp. 914-927
-
-
Karsli-Uzunbas, G.1
Guo, J.Y.2
Price, S.3
Teng, X.4
Laddha, S.V.5
Khor, S.6
Kalaany, N.Y.7
Jacks, T.8
Chan, C.S.9
Rabinowitz, J.D.10
-
33
-
-
77956420489
-
Can autophagy promote longevity?
-
PMID:20811357
-
Madeo F, Tavernarakis N, Kroemer G. Can autophagy promote longevity? Nat Cell Biol 2010; 12:842-6;PMID:20811357; http://dx.doi.org/10.1038/ncb0910-842.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 842-846
-
-
Madeo, F.1
Tavernarakis, N.2
Kroemer, G.3
-
34
-
-
84896903811
-
Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/ betaA3/A1-crystallin via V-ATPase-MTORC1 signaling
-
PMID:24468901
-
Valapala M, Wilson C, Hose S, Bhutto IA, Grebe R, Dong A, Greenbaum S, Gu L, Sengupta S, Cano M, et al. Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/ betaA3/A1-crystallin via V-ATPase-MTORC1 signaling. Autophagy 2014; 10:480-96; PMID:24468901; http://dx.doi.org/10.4161/auto.27292.
-
(2014)
Autophagy
, vol.10
, pp. 480-496
-
-
Valapala, M.1
Wilson, C.2
Hose, S.3
Bhutto, I.A.4
Grebe, R.5
Dong, A.6
Greenbaum, S.7
Gu, L.8
Sengupta, S.9
Cano, M.10
-
35
-
-
0030466371
-
The retardation of aging by caloric restriction: Studies in rodents and primates
-
PMID:8994305
-
Weindruch R. The retardation of aging by caloric restriction: studies in rodents and primates. Toxicol Pathol 1996; 24:742-5; PMID:8994305; http://dx.doi.org/10.1177/019262339602400618.
-
(1996)
Toxicol Pathol
, vol.24
, pp. 742-745
-
-
Weindruch, R.1
-
36
-
-
84868101259
-
The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction
-
PMID:22868943
-
Rascon B, Hubbard BP, Sinclair DA, Amdam GV. The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction. Aging 2012; 4:499-508; PMID:22868943.
-
(2012)
Aging
, vol.4
, pp. 499-508
-
-
Rascon, B.1
Hubbard, B.P.2
Sinclair, D.A.3
Amdam, G.V.4
-
37
-
-
51649088498
-
The relationship of dietary omega-3 long-chain polyunsaturated fatty acid intake with incident age-related macular degeneration: AREDS report no. 23
-
PMID:18779490
-
SanGiovanni JP, Chew EY, Agron E, Clemons TE, Ferris FL, 3rd, Gensler G, Lindblad AS, Milton RC, Seddon JM, Klein R, et al. The relationship of dietary omega-3 long-chain polyunsaturated fatty acid intake with incident age-related macular degeneration: AREDS report no. 23. Arch Ophthalmol 2008; 126:1274-9; PMID:18779490; http://dx.doi.org/10.1001/archopht.126.9.1274.
-
(2008)
Arch Ophthalmol
, vol.126
, pp. 1274-1279
-
-
Sangiovanni, J.P.1
Chew, E.Y.2
Agron, E.3
Clemons, T.E.4
Ferris, F.L.5
Gensler, G.6
Lindblad, A.S.7
Milton, R.C.8
Seddon, J.M.9
Klein, R.10
-
38
-
-
0344305692
-
Progression of agerelated macular degeneration: Association with dietary fat, transunsaturated fat, nuts, and fish intake
-
PMID:14662593
-
Seddon JM, Cote J, Rosner B. Progression of agerelated macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish intake. Arch Ophthalmol 2003; 121:1728-37; PMID:14662593; http://dx.doi.org/10.1001/archopht.121.12.1728.
-
(2003)
Arch Ophthalmol
, vol.121
, pp. 1728-1737
-
-
Seddon, J.M.1
Cote, J.2
Rosner, B.3
-
39
-
-
33745839872
-
Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: The US Twin Study of Age-Related Macular Degeneration
-
PMID:16832023
-
Seddon JM, George S, Rosner B. Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: the US Twin Study of Age-Related Macular Degeneration. Arch Ophthalmol 2006; 124:995-1001;PMID:16832023; http://dx.doi.org/10.1001/archopht.124.7.995.
-
(2006)
Arch Ophthalmol
, vol.124
, pp. 995-1001
-
-
Seddon, J.M.1
George, S.2
Rosner, B.3
-
40
-
-
45149132510
-
Dietary omega-3 fatty acid and fish intake in the primary prevention of age-related macular degeneration: A systematic review and meta-analysis
-
PMID:18541848
-
Chong EW, Kreis AJ, Wong TY, Simpson JA, Guymer RH. Dietary omega-3 fatty acid and fish intake in the primary prevention of age-related macular degeneration: a systematic review and meta-analysis. Archives of ophthalmology 2008; 126:826-33;PMID:18541848; http://dx.doi.org/10.1001/archopht.126.6.826.
-
(2008)
Archives of Ophthalmology
, vol.126
, pp. 826-833
-
-
Chong, E.W.1
Kreis, A.J.2
Wong, T.Y.3
Simpson, J.A.4
Guymer, R.H.5
-
41
-
-
84875770625
-
High concentrations of plasma n3 fatty acids are associated with decreased risk for late age-related macular degeneration
-
PMID:23406618
-
Merle BM, Delyfer MN, Korobelnik JF, Rougier MB, Malet F, Feart C, Le Goff M, Peuchant E, Letenneur L, Dartigues JF, et al. High concentrations of plasma n3 fatty acids are associated with decreased risk for late age-related macular degeneration. J Nutr 2013; 143:505-11; PMID:23406618; http://dx.doi.org/10.3945/jn.112.171033.
-
(2013)
J Nutr
, vol.143
, pp. 505-511
-
-
Merle, B.M.1
Delyfer, M.N.2
Korobelnik, J.F.3
Rougier, M.B.4
Malet, F.5
Feart, C.6
Le Goff, M.7
Peuchant, E.8
Letenneur, L.9
Dartigues, J.F.10
-
42
-
-
84897140274
-
Nutritional AMDTSG. Circulating omega-3 Fatty acids and neovascular age-related macular degeneration
-
PMID:24557349
-
Merle BM, Benlian P, Puche N, Bassols A, Delcourt C, Souied EH, Nutritional AMDTSG. Circulating omega-3 Fatty acids and neovascular age-related macular degeneration. Invest Ophthalmol Visual Sci 2014; 55:2010-9; PMID:24557349; http://dx.doi.org/10.1167/iovs.14-13916.
-
(2014)
Invest Ophthalmol Visual Sci
, vol.55
, pp. 2010-2019
-
-
Merle, B.M.1
Benlian, P.2
Puche, N.3
Bassols, A.4
Delcourt, C.5
Souied, E.H.6
-
43
-
-
80052235755
-
Differential anti-cancer effects of purified EPA and DHA and possible mechanisms involved
-
PMID:21824086
-
Serini S, Fasano E, Piccioni E, Cittadini AR, Calviello G. Differential anti-cancer effects of purified EPA and DHA and possible mechanisms involved. Curr Med Chem 2011; 18:4065-75; PMID:21824086; http://dx.doi.org/10.2174/092986711796957310.
-
(2011)
Curr Med Chem
, vol.18
, pp. 4065-4075
-
-
Serini, S.1
Fasano, E.2
Piccioni, E.3
Cittadini, A.R.4
Calviello, G.5
-
44
-
-
69449087035
-
Cellular and molecular events mediated by docosahexaenoic acid-derived neuroprotectin D1 signaling in photoreceptor cell survival and brain protection
-
PMID:19520558
-
Bazan NG. Cellular and molecular events mediated by docosahexaenoic acid-derived neuroprotectin D1 signaling in photoreceptor cell survival and brain protection. Prostaglandins Leukot Essent Fatty Acids 2009; 81:205-11; PMID:19520558; http://dx.doi.org/10.1016/j.plefa.2009.05.024.
-
(2009)
Prostaglandins Leukot Essent Fatty Acids
, vol.81
, pp. 205-211
-
-
Bazan, N.G.1
-
45
-
-
0024652027
-
Coronary heart disease in Greenland Inuit: A paradox. Implications for western diet patterns
-
PMID:2736000
-
Dyerberg J. Coronary heart disease in Greenland Inuit: a paradox. Implications for western diet patterns. Arctic Med Res 1989; 48:47-54;PMID:2736000.
-
(1989)
Arctic Med Res
, vol.48
, pp. 47-54
-
-
Dyerberg, J.1
-
46
-
-
0037700424
-
Fish consumption and the risk of Alzheimer disease: Is it time to make dietary recommendations?
-
PMID:12873846
-
Friedland RP. Fish consumption and the risk of Alzheimer disease: is it time to make dietary recommendations? Arch Neurol 2003; 60:923-4;PMID:12873846; http://dx.doi.org/10.1001/archneur.60.7.923.
-
(2003)
Arch Neurol
, vol.60
, pp. 923-924
-
-
Friedland, R.P.1
-
47
-
-
0029068579
-
Fish, n-3 fatty acids and human colorectal and breast cancer mortality
-
PMID:7549825
-
Caygill CP, Hill MJ. Fish, n-3 fatty acids and human colorectal and breast cancer mortality. Eur J Cancer Prev 1995; 4:329-32; PMID:7549825; http://dx.doi.org/10.1097/00008469-199508000-00008.
-
(1995)
Eur J Cancer Prev
, vol.4
, pp. 329-332
-
-
Caygill, C.P.1
Hill, M.J.2
-
48
-
-
80655134737
-
Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53
-
PMID:21811093
-
Jing K, Song KS, Shin S, Kim N, Jeong S, Oh HR, Park JH, Seo KS, Heo JY, Han J, et al. Docosahexaenoic acid induces autophagy through p53/AMPK/mTOR signaling and promotes apoptosis in human cancer cells harboring wild-type p53. Autophagy 2011; 7:1348-58; PMID:21811093; http://dx.doi. org/10.4161/auto.7.11.16658.
-
(2011)
Autophagy
, vol.7
, pp. 1348-1358
-
-
Jing, K.1
Song, K.S.2
Shin, S.3
Kim, N.4
Jeong, S.5
Oh, H.R.6
Park, J.H.7
Seo, K.S.8
Heo, J.Y.9
Han, J.10
-
49
-
-
84874218519
-
Omega-3 PUFA ethanolamides DHEA and EPEA induce autophagy through PPARgamma activation in MCF-7 breast cancer cells
-
PMID:23168911
-
Rovito D, Giordano C, Vizza D, Plastina P, Barone I, Casaburi I, Lanzino M, De Amicis F, Sisci D, Mauro L, et al. Omega-3 PUFA ethanolamides DHEA and EPEA induce autophagy through PPARgamma activation in MCF-7 breast cancer cells. J Cell Physiol 2013; 228:1314-22; PMID:23168911; http://dx.doi.org/10.1002/jcp.24288.
-
(2013)
J Cell Physiol
, vol.228
, pp. 1314-1322
-
-
Rovito, D.1
Giordano, C.2
Vizza, D.3
Plastina, P.4
Barone, I.5
Casaburi, I.6
Lanzino, M.7
De Amicis, F.8
Sisci, D.9
Mauro, L.10
-
50
-
-
84880124645
-
The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROSmediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53
-
PMID:23841076
-
Shin S, Jing K, Jeong S, Kim N, Song KS, Heo JY, Park JH, Seo KS, Han J, Park JI, et al. The omega-3 polyunsaturated fatty acid DHA induces simultaneous apoptosis and autophagy via mitochondrial ROSmediated Akt-mTOR signaling in prostate cancer cells expressing mutant p53. Biomed Res Int 2013; 2013:568671; PMID:23841076; http://dx.doi.org/10.1155/2013/568671.
-
(2013)
Biomed Res Int
, vol.2013
, pp. 568671
-
-
Shin, S.1
Jing, K.2
Jeong, S.3
Kim, N.4
Song, K.S.5
Heo, J.Y.6
Park, J.H.7
Seo, K.S.8
Han, J.9
Park, J.I.10
-
51
-
-
84902673006
-
Omega-3 free fatty acids suppress macrophage inflammasome activation by inhibiting NF-kappaB activation and enhancing autophagy
-
PMID:24911523
-
Williams-Bey Y, Boularan C, Vural A, Huang NN, Hwang IY, Shan-Shi C, Kehrl JH. Omega-3 free fatty acids suppress macrophage inflammasome activation by inhibiting NF-kappaB activation and enhancing autophagy. PloS One 2014; 9:e97957;PMID:24911523; http://dx.doi.org/10.1371/journal.pone.0097957.
-
(2014)
Plos One
, vol.9
-
-
Williams-Bey, Y.1
Boularan, C.2
Vural, A.3
Huang, N.N.4
Hwang, I.Y.5
Shan-Shi, C.6
Kehrl, J.H.7
-
52
-
-
84896715810
-
Eicosapentaenoic acid attenuated oxidative stress-induced cardiomyoblast apoptosis by activating adaptive autophagy
-
PMID:23887854
-
Hsu HC, Chen CY, Chiang CH, Chen MF. Eicosapentaenoic acid attenuated oxidative stress-induced cardiomyoblast apoptosis by activating adaptive autophagy. Eur J Nutr 2014; 53:541-7;PMID:23887854; http://dx.doi.org/10.1007/s00394-013-0562-2.
-
(2014)
Eur J Nutr
, vol.53
, pp. 541-547
-
-
Hsu, H.C.1
Chen, C.Y.2
Chiang, C.H.3
Chen, M.F.4
-
53
-
-
84869392417
-
EPA, an omega-3 fatty acid, induces apoptosis in human pancreatic cancer cells: Role of ROS accumulation, caspase-8 activation, and autophagy induction
-
PMID:22903547
-
Fukui M, Kang KS, Okada K, Zhu BT. EPA, an omega-3 fatty acid, induces apoptosis in human pancreatic cancer cells: role of ROS accumulation, caspase-8 activation, and autophagy induction. J Cell Biochem 2013; 114:192-203; PMID:22903547; http://dx.doi.org/10.1002/jcb.24354.
-
(2013)
J Cell Biochem
, vol.114
, pp. 192-203
-
-
Fukui, M.1
Kang, K.S.2
Okada, K.3
Zhu, B.T.4
-
54
-
-
33846257298
-
Enhanced incorporation of n-3 fatty acids from fish compared with fish oils
-
PMID:17269556
-
Elvevoll EO, Barstad H, Breimo ES, Brox J, Eilertsen KE, Lund T, Olsen JO, Osterud B. Enhanced incorporation of n-3 fatty acids from fish compared with fish oils. Lipids 2006; 41:1109-14; PMID:17269556; http://dx.doi.org/10.1007/s11745-006-5060-3.
-
(2006)
Lipids
, vol.41
, pp. 1109-1114
-
-
Elvevoll, E.O.1
Barstad, H.2
Breimo, E.S.3
Brox, J.4
Eilertsen, K.E.5
Lund, T.6
Olsen, J.O.7
Osterud, B.8
-
55
-
-
0029872876
-
ARPE-19, a human retinal pigment epithelial cell line with differentiated properties
-
PMID:8698076
-
Dunn KC, Aotaki-Keen AE, Putkey FR, Hjelmeland LM. ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res 1996; 62:155-69; PMID:8698076; http://dx.doi.org/10.1006/exer.1996.0020.
-
(1996)
Exp Eye Res
, vol.62
, pp. 155-169
-
-
Dunn, K.C.1
Aotaki-Keen, A.E.2
Putkey, F.R.3
Hjelmeland, L.M.4
-
56
-
-
84877263161
-
Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitro
-
PMID:23663688
-
Dai J, Shen J, Pan W, Shen S, Das UN. Effects of polyunsaturated fatty acids on the growth of gastric cancer cells in vitro. Lipids Health Dis 2013; 12:71;PMID:23663688; http://dx.doi.org/10.1186/1476-511X-12-71.
-
(2013)
Lipids Health Dis
, vol.12
, pp. 71
-
-
Dai, J.1
Shen, J.2
Pan, W.3
Shen, S.4
Das, U.N.5
-
57
-
-
58849102749
-
DHA induces ER stress and growth arrest in human colon cancer cells: Associations with cholesterol and calcium homeostasis
-
PMID:18566476
-
Jakobsen CH, Storvold GL, Bremseth H, Follestad T, Sand K, Mack M, Olsen KS, Lundemo AG, Iversen JG, Krokan HE, et al. DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis. J Lipid Res 2008; 49:2089-100; PMID:18566476; http://dx.doi.org/10.1194/jlr.M700389-JLR200.
-
(2008)
J Lipid Res
, vol.49
, pp. 2089-2100
-
-
Jakobsen, C.H.1
Storvold, G.L.2
Bremseth, H.3
Follestad, T.4
Sand, K.5
Mack, M.6
Olsen, K.S.7
Lundemo, A.G.8
Iversen, J.G.9
Krokan, H.E.10
-
58
-
-
84897421970
-
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
-
PMID:24647116
-
Hayes JD, Dinkova-Kostova AT. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Trends Biochem Sci 2014; 39:199-218; PMID:24647116; http://dx.doi.org/10.1016/j.tibs.2014.02.002.
-
(2014)
Trends Biochem Sci
, vol.39
, pp. 199-218
-
-
Hayes, J.D.1
Dinkova-Kostova, A.T.2
-
59
-
-
20444456655
-
Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: Role of mitogen-activated protein kinases and Nrf2
-
PMID:15964514
-
Anwar AA, Li FY, Leake DS, Ishii T, Mann GE, Siow RC. Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2. Free Radic Biol Med 2005; 39:227-36; PMID:15964514; http://dx.doi.org/10.1016/j.freeradbiomed.2005.03.012.
-
(2005)
Free Radic Biol Med
, vol.39
, pp. 227-236
-
-
Anwar, A.A.1
Li, F.Y.2
Leake, D.S.3
Ishii, T.4
Mann, G.E.5
Siow, R.C.6
-
60
-
-
84865287281
-
Keap1 degradation by autophagy for the maintenance of redox homeostasis
-
PMID:22872865
-
Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, Yamamoto M. Keap1 degradation by autophagy for the maintenance of redox homeostasis. Proc Natl Acad Sci U S A 2012; 109:13561-6; PMID:22872865; http://dx.doi.org/10.1073/pnas.1121572109.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 13561-13566
-
-
Taguchi, K.1
Fujikawa, N.2
Komatsu, M.3
Ishii, T.4
Unno, M.5
Akaike, T.6
Motohashi, H.7
Yamamoto, M.8
-
61
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3- based E3 ligase to regulate proteasomal degradation of Nrf2
-
PMID:15282312
-
Kobayashi A, Kang MI, Okawa H, Ohtsuji M, Zenke Y, Chiba T, Igarashi K, Yamamoto M. Oxidative stress sensor Keap1 functions as an adaptor for Cul3- based E3 ligase to regulate proteasomal degradation of Nrf2. Mol Cell Biol 2004; 24:7130-9;PMID:15282312; http://dx.doi.org/10.1128/MCB.24.16.7130-7139.2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7130-7139
-
-
Kobayashi, A.1
Kang, M.I.2
Okawa, H.3
Ohtsuji, M.4
Zenke, Y.5
Chiba, T.6
Igarashi, K.7
Yamamoto, M.8
-
62
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
PMID:9887101
-
Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, Yamamoto M. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 1999; 13:76-86;PMID:9887101; http://dx.doi.org/10.1101/gad.13.1.76.
-
(1999)
Genes Dev
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
63
-
-
77953366801
-
A noncanonical mechanism of Nrf2 activation by autophagy deficiency: Direct interaction between Keap1 and p62
-
PMID:20421418
-
Lau A, Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD. A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62. Mol Cell Biol 2010; 30:3275-85; PMID:20421418; http://dx.doi.org/10.1128/MCB.00248-10.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 3275-3285
-
-
Lau, A.1
Wang, X.J.2
Zhao, F.3
Villeneuve, N.F.4
Wu, T.5
Jiang, T.6
Sun, Z.7
White, E.8
Zhang, D.D.9
-
64
-
-
77954599053
-
P62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
-
PMID:20452972
-
Jain A, Lamark T, Sjottem E, Larsen KB, Awuh JA, Overvatn A, McMahon M, Hayes JD, Johansen T. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. J Biol Chem 2010; 285:22576-91; PMID:20452972; http://dx.doi.org/10.1074/jbc.M110.118976
-
(2010)
J Biol Chem
, vol.285
, pp. 22576-22591
-
-
Jain, A.1
Lamark, T.2
Sjottem, E.3
Larsen, K.B.4
Awuh, J.A.5
Overvatn, A.6
McMahon, M.7
Hayes, J.D.8
Johansen, T.9
-
65
-
-
77649265091
-
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
-
PMID:20173742
-
Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, et al. The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol 2010; 12:213-23; PMID:20173742
-
(2010)
Nat Cell Biol
, vol.12
, pp. 213-223
-
-
Komatsu, M.1
Kurokawa, H.2
Waguri, S.3
Taguchi, K.4
Kobayashi, A.5
Ichimura, Y.6
Sou, Y.S.7
Ueno, I.8
Sakamoto, A.9
Tong, K.I.10
-
66
-
-
84883830467
-
Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
-
PMID:24011591
-
Ichimura Y, Waguri S, Sou Y-S, Kageyama S, Hasegawa J, Ishimura R, Saito T, Yang Y, Kouno T, Fukutomi T, et al. Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy. Mol Cell 2013; 51:618-31; PMID:24011591; http://dx.doi.org/10.1016/j.molcel.2013.08.003
-
(2013)
Mol Cell
, vol.51
, pp. 618-631
-
-
Ichimura, Y.1
Waguri, S.2
Sou, Y.-S.3
Kageyama, S.4
Hasegawa, J.5
Ishimura, R.6
Saito, T.7
Yang, Y.8
Kouno, T.9
Fukutomi, T.10
-
67
-
-
33646204392
-
Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size
-
PMID:16647067
-
Hosokawa N, Hara Y, Mizushima N. Generation of cell lines with tetracycline-regulated autophagy and a role for autophagy in controlling cell size. FEBS Lett 2006; 580:2623-9; PMID:16647067; http://dx.doi.org/10.1016/j.febslet.2006.04.008
-
(2006)
FEBS Lett
, vol.580
, pp. 2623-2629
-
-
Hosokawa, N.1
Hara, Y.2
Mizushima, N.3
-
68
-
-
84892859905
-
Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy
-
PMID:24462201
-
Rogov V, Dotsch V, Johansen T, Kirkin V. Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy. Mol Cell 2014; 53:167-78; PMID:24462201; http://dx.doi.org/10.1016/j.molcel.2013.12.014
-
(2014)
Mol Cell
, vol.53
, pp. 167-178
-
-
Rogov, V.1
Dotsch, V.2
Johansen, T.3
Kirkin, V.4
-
69
-
-
33745824614
-
ALIS are stress-induced protein storage compartments for substrates of the proteasome and autophagy
-
PMID:16874109
-
Szeto J, Kaniuk NA, Canadien V, Nisman R, Mizushima N, Yoshimori T, Bazett-Jones DP, Brumell JH. ALIS are stress-induced protein storage compartments for substrates of the proteasome and autophagy. Autophagy 2006; 2:189-99; PMID:16874109; http://dx.doi.org/10.4161/auto.2731.
-
(2006)
Autophagy
, vol.2
, pp. 189-199
-
-
Szeto, J.1
Kaniuk, N.A.2
Canadien, V.3
Nisman, R.4
Mizushima, N.5
Yoshimori, T.6
Bazett-Jones, D.P.7
Brumell, J.H.8
-
70
-
-
84921533914
-
Dual labeling with 5-bromo-20-deoxyuridine and 5-ethynyl-20-deoxyuridine for estimation of cell migration rate in the small intestinal epithelium
-
Asano M, Yamamoto T, Tsuruta T, Nishimura N, Sonoyama K. Dual labeling with 5-bromo-20-deoxyuridine and 5-ethynyl-20-deoxyuridine for estimation of cell migration rate in the small intestinal epithelium. Dev Growth Differ 2014; 57(1):68-73.
-
(2014)
Dev Growth Differ
, vol.57
, Issue.1
, pp. 68-73
-
-
Asano, M.1
Yamamoto, T.2
Tsuruta, T.3
Nishimura, N.4
Sonoyama, K.5
-
71
-
-
65949121134
-
Oxidative stress and neurodegenerative diseases: A review of upstream and downstream antioxidant therapeutic options
-
PMID:19721819
-
Uttara B, Singh AV, Zamboni P, Mahajan RT. Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Curr Neuropharmacol 2009; 7:65-74; PMID:19721819; http://dx.doi.org/10.2174/157015909787602823.
-
(2009)
Curr Neuropharmacol
, vol.7
, pp. 65-74
-
-
Uttara, B.1
Singh, A.V.2
Zamboni, P.3
Mahajan, R.T.4
-
72
-
-
84864348569
-
NRF2 and cancer: The good, the bad and the importance of context
-
PMID:22810811
-
Sporn MB, Liby KT. NRF2 and cancer: the good, the bad and the importance of context. Nat Rev Cancer 2012; 12:564-71; PMID:22810811; http://dx.doi.org/10.1038/nrc3278.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 564-571
-
-
Sporn, M.B.1
Liby, K.T.2
-
73
-
-
79955765832
-
Age-related retinopathy in NRF2-deficient mice
-
PMID:21559389
-
Zhao Z, Chen Y, Wang J, Sternberg P, Freeman ML, Grossniklaus HE, Cai J. Age-related retinopathy in NRF2-deficient mice. PloS One 2011; 6:e19456; PMID:21559389; http://dx.doi.org/10.1371/journal.pone.0019456.
-
(2011)
Plos One
, vol.6
-
-
Zhao, Z.1
Chen, Y.2
Wang, J.3
Sternberg, P.4
Freeman, M.L.5
Grossniklaus, H.E.6
Cai, J.7
-
74
-
-
34047273206
-
Novel n-3 fatty acid oxidation products activate Nrf2 by destabilizing the association between Keap1 and Cullin3
-
PMID:17127771
-
Gao L, Wang J, Sekhar KR, Yin H, Yared NF, Schneider SN, Sasi S, Dalton TP, Anderson ME, Chan JY, et al. Novel n-3 fatty acid oxidation products activate Nrf2 by destabilizing the association between Keap1 and Cullin3. J Biol Chem 2007; 282:2529-37; PMID:17127771; http://dx.doi.org/10.1074/jbc.M607622200.
-
(2007)
J Biol Chem
, vol.282
, pp. 2529-2537
-
-
Gao, L.1
Wang, J.2
Sekhar, K.R.3
Yin, H.4
Yared, N.F.5
Schneider, S.N.6
Sasi, S.7
Dalton, T.P.8
Erson, M.E.9
Chan, J.Y.10
-
75
-
-
84899725321
-
Generation and dietary modulation of anti-inflammatory electrophilic omega-3 fatty acid derivatives
-
PMID:24736647
-
Cipollina C, Salvatore SR, Muldoon MF, Freeman BA, Schopfer FJ. Generation and dietary modulation of anti-inflammatory electrophilic omega-3 fatty acid derivatives. PloS One 2014; 9:e94836; PMID:24736647; http://dx.doi.org/10.1371/journal.pone.0094836.
-
(2014)
Plos One
, vol.9
-
-
Cipollina, C.1
Salvatore, S.R.2
Muldoon, M.F.3
Freeman, B.A.4
Schopfer, F.J.5
-
76
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132:27-42; PMID:18191218; http://dx.doi.org/10.1016/j.cell.2007.12.018
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
77
-
-
57649203344
-
Autophagy in aging, disease and death: The true identity of a cell death impostor
-
PMID:19079285
-
Levine B, Kroemer G. Autophagy in aging, disease and death: the true identity of a cell death impostor. Cell Death Differ 2009; 16:1-2; PMID:19079285; http://dx.doi.org/10.1038/cdd.2008.139.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1-2
-
-
Levine, B.1
Kroemer, G.2
-
78
-
-
33750363298
-
The roles of intracellular proteindegradation pathways in neurodegeneration
-
PMID:17051204
-
Rubinsztein DC. The roles of intracellular proteindegradation pathways in neurodegeneration. Nature 2006; 443:780-6; PMID:17051204; http://dx.doi.org/10.1038/nature05291.
-
(2006)
Nature
, vol.443
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
79
-
-
84876570034
-
Deletion of autophagy-related 5 (Atg5) and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation
-
PMID:23479732
-
Morishita H, Eguchi S, Kimura H, Sasaki J, Sakamaki Y, Robinson ML, Sasaki T, Mizushima N. Deletion of autophagy-related 5 (Atg5) and Pik3c3 genes in the lens causes cataract independent of programmed organelle degradation. J Biol Chem 2013; 288:11436-47; PMID:23479732; http://dx.doi.org/10.1074/jbc.M112.437103.
-
(2013)
J Biol Chem
, vol.288
, pp. 11436-11447
-
-
Morishita, H.1
Eguchi, S.2
Kimura, H.3
Sasaki, J.4
Sakamaki, Y.5
Robinson, M.L.6
Sasaki, T.7
Mizushima, N.8
-
80
-
-
84880551919
-
Noncanonical autophagy promotes the visual cycle
-
PMID:23870125
-
Kim JY, Zhao H, Martinez J, Doggett TA, Kolesnikov AV, Tang PH, Ablonczy Z, Chan CC, Zhou Z, Green DR, et al. Noncanonical autophagy promotes the visual cycle. Cell 2013; 154:365-76; PMID:23870125; http://dx.doi.org/10.1016/j.cell.2013.06.012.
-
(2013)
Cell
, vol.154
, pp. 365-376
-
-
Kim, J.Y.1
Zhao, H.2
Martinez, J.3
Doggett, T.A.4
Kolesnikov, A.V.5
Tang, P.H.6
Ablonczy, Z.7
Chan, C.C.8
Zhou, Z.9
Green, D.R.10
-
81
-
-
85005842121
-
Retinal damage in chloroquine maculopathy, revealed by high resolution imaging: A case report utilizing adaptive optics scanning laser ophthalmoscopy
-
PMID:24505207
-
Bae EJ, Kim KR, Tsang SH, Park SP, Chang S. Retinal damage in chloroquine maculopathy, revealed by high resolution imaging: a case report utilizing adaptive optics scanning laser ophthalmoscopy. Korean J Ophthalmol 2014; 28:100-7; PMID:24505207; http://dx.doi.org/10.3341/kjo.2014.28.1.100.
-
(2014)
Korean J Ophthalmol
, vol.28
, pp. 100-107
-
-
Bae, E.J.1
Kim, K.R.2
Tsang, S.H.3
Park, S.P.4
Chang, S.5
-
82
-
-
84877819153
-
Balance between autophagic pathways preserves retinal homeostasis
-
PMID:23521856
-
Rodriguez-Muela N, Koga H, Garcia-Ledo L, de la Villa P, de la Rosa EJ, Cuervo AM, Boya P. Balance between autophagic pathways preserves retinal homeostasis. Aging cell 2013; 12:478-88; PMID:23521856; http://dx.doi.org/10.1111/acel.12072.
-
(2013)
Aging Cell
, vol.12
, pp. 478-488
-
-
Rodriguez-Muela, N.1
Koga, H.2
Garcia-Ledo, L.3
De La Villa, P.4
De La Rosa, E.J.5
Cuervo, A.M.6
Boya, P.7
-
83
-
-
11144353613
-
SUMO modification of Huntingtin and Huntington’s disease pathology
-
PMID:15064418
-
Steffan JS, Agrawal N, Pallos J, Rockabrand E, Trotman LC, Slepko N, Illes K, Lukacsovich T, Zhu YZ, Cattaneo E, et al. SUMO modification of Huntingtin and Huntington’s disease pathology. Science 2004; 304:100-4; PMID:15064418; http://dx.doi.org/10.1126/science.1092194.
-
(2004)
Science
, vol.304
, pp. 100-104
-
-
Steffan, J.S.1
Agrawal, N.2
Pallos, J.3
Rockabrand, E.4
Trotman, L.C.5
Slepko, N.6
Illes, K.7
Lukacsovich, T.8
Zhu, Y.Z.9
Cattaneo, E.10
-
84
-
-
0036566266
-
Aggregateprone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
-
PMID:11978769
-
Ravikumar B, Duden R, Rubinsztein DC. Aggregateprone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Hum Mol Genet 2002; 11:1107-17; PMID:11978769; http://dx.doi.org/10.1093/hmg/11.9.1107.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1107-1117
-
-
Ravikumar, B.1
Duden, R.2
Rubinsztein, D.C.3
-
85
-
-
44449090993
-
Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: A pathway for latestage quality control
-
PMID:18391222
-
Pan M, Maitin V, Parathath S, Andreo U, Lin SX, St Germain C, Yao Z, Maxfield FR, Williams KJ, Fisher EA. Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: a pathway for latestage quality control. Proc Natl Acad Sci U S A 2008; 105:5862-7; PMID:18391222; http://dx.doi.org/10.1073/pnas.0707460104.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 5862-5867
-
-
Pan, M.1
Maitin, V.2
Parathath, S.3
Reo, U.4
Lin, S.X.5
St Germain, C.6
Yao, Z.7
Maxfield, F.R.8
Williams, K.J.9
Fisher, E.A.10
-
86
-
-
66449099090
-
Autophagy suppresses tumorigenesis through elimination of p62
-
PMID:19524509
-
Mathew R, Karp CM, Beaudoin B, Vuong N, Chen G, Chen HY, Bray K, Reddy A, Bhanot G, Gelinas C, et al. Autophagy suppresses tumorigenesis through elimination of p62. Cell 2009; 137:1062-75; PMID:19524509; http://dx.doi.org/10.1016/j.cell.2009.03.048.
-
(2009)
Cell
, vol.137
, pp. 1062-1075
-
-
Mathew, R.1
Karp, C.M.2
Beaudoin, B.3
Vuong, N.4
Chen, G.5
Chen, H.Y.6
Bray, K.7
Reddy, A.8
Bhanot, G.9
Gelinas, C.10
-
87
-
-
79955929541
-
Transcriptional regulation of activating transcription factor 4 under oxidative stress in retinal pigment epithelial ARPE- 19/HPV-16 cells
-
PMID:21087962
-
Miyamoto N, Izumi H, Miyamoto R, Bin H, Kondo H, Tawara A, Sasaguri Y, Kohno K. Transcriptional regulation of activating transcription factor 4 under oxidative stress in retinal pigment epithelial ARPE- 19/HPV-16 cells. Invest Ophthalmol Vis Sci 2011; PMID:21087962; http://dx.doi.org/10.1167/iovs.10-5775.
-
(2011)
Invest Ophthalmol Vis Sci
-
-
Miyamoto, N.1
Izumi, H.2
Miyamoto, R.3
Bin, H.4
Kondo, H.5
Tawara, A.6
Sasaguri, Y.7
Kohno, K.8
-
88
-
-
84885455062
-
The eIF2alpha/ATF4 pathway is essential for stress-induced autophagy gene expression
-
PMID:23804767
-
B’Chir W, Maurin AC, Carraro V, Averous J, Jousse C, Muranishi Y, Parry L, Stepien G, Fafournoux P, Bruhat A. The eIF2alpha/ATF4 pathway is essential for stress-induced autophagy gene expression. Nucleic Acids Res 2013; 41:7683-99; PMID:23804767; http://dx.doi.org/10.1093/nar/gkt563.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 7683-7699
-
-
B’Chir, W.1
Maurin, A.C.2
Carraro, V.3
Averous, J.4
Jousse, C.5
Muranishi, Y.6
Parry, L.7
Stepien, G.8
Fafournoux, P.9
Bruhat, A.10
-
89
-
-
77955467319
-
Regulation of autophagy by ATF4 in response to severe hypoxia
-
PMID:20514020
-
Rzymski T, Milani M, Pike L, Buffa F, Mellor HR, Winchester L, Pires I, Hammond E, Ragoussis I, Harris AL. Regulation of autophagy by ATF4 in response to severe hypoxia. Oncogene 2010; 29:4424-35; PMID:20514020; http://dx.doi.org/10.1038/onc.2010.191.
-
(2010)
Oncogene
, vol.29
, pp. 4424-4435
-
-
Rzymski, T.1
Milani, M.2
Pike, L.3
Buffa, F.4
Mellor, H.R.5
Winchester, L.6
Pires, I.7
Hammond, E.8
Ragoussis, I.9
Harris, A.L.10
-
90
-
-
80955177196
-
TFEB links autophagy to lysosomal biogenesis
-
PMID:21617040
-
Settembre C, Di Malta C, Polito VA, Garcia Arencibia M, Vetrini F, Erdin S, Erdin SU, Huynh T, Medina D, Colella P, et al. TFEB links autophagy to lysosomal biogenesis. Science 2011; 332:1429-33; PMID:21617040; http://dx.doi.org/10.1126/science.1204592.
-
(2011)
Science
, vol.332
, pp. 1429-1433
-
-
Settembre, C.1
Di Malta, C.2
Polito, V.A.3
Garcia Arencibia, M.4
Vetrini, F.5
Erdin, S.6
Erdin, S.U.7
Huynh, T.8
Medina, D.9
Colella, P.10
-
91
-
-
84922968506
-
Transcriptional regulation of autophagy by an FXR-CREB axis
-
PMID:25383523
-
Seok S, Fu T, Choi SE, Li Y, Zhu R, Kumar S, Sun X, Yoon G, Kang Y, Zhong W, et al. Transcriptional regulation of autophagy by an FXR-CREB axis. Nature 2014; 516:108-11; PMID:25383523.
-
(2014)
Nature
, vol.516
, pp. 108-111
-
-
Seok, S.1
Fu, T.2
Choi, S.E.3
Li, Y.4
Zhu, R.5
Kumar, S.6
Sun, X.7
Yoon, G.8
Kang, Y.9
Zhong, W.10
-
92
-
-
84923031534
-
Nutrient-sensing nuclear receptors coordinate autophagy
-
Lee JM, Wagner M, Xiao R, Kim KH, Feng D, Lazar MA, Moore DD. Nutrient-sensing nuclear receptors coordinate autophagy. Nature 2014; 516:112-5; PMID:25383539
-
(2014)
Nature
, vol.516
, pp. 112-115
-
-
Lee, J.M.1
Wagner, M.2
Xiao, R.3
Kim, K.H.4
Feng, D.5
Lazar, M.A.6
Moore, D.D.7
-
93
-
-
84861600073
-
Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration
-
PMID:22112056
-
Kinnunen K, Petrovski G, Moe MC, Berta A, Kaarniranta K. Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration. Acta Ophthalmol 2012; 90:299-309; PMID:22112056; http://dx.doi.org/10.1111/j.1755-3768.2011.02179.x.
-
(2012)
Acta Ophthalmol
, vol.90
, pp. 299-309
-
-
Kinnunen, K.1
Petrovski, G.2
Moe, M.C.3
Berta, A.4
Kaarniranta, K.5
-
94
-
-
84863727273
-
Understanding age-related macular degeneration (AMD): Relationships between the photoreceptor/retinal pigment epithelium/Bruch’s membrane/choriocapillaris complex
-
PMID:22542780
-
Bhutto I, Lutty G. Understanding age-related macular degeneration (AMD): relationships between the photoreceptor/retinal pigment epithelium/Bruch’s membrane/choriocapillaris complex. Mol Aspects Med 2012; 33:295-317; PMID:22542780; http://dx.doi.org/10.1016/j.mam.2012.04.005.
-
(2012)
Mol Aspects Med
, vol.33
, pp. 295-317
-
-
Bhutto, I.1
Lutty, G.2
-
95
-
-
65649087058
-
Fat consumption and its association with age-related macular degeneration
-
PMID:19433719
-
Chong EW, Robman LD, Simpson JA, Hodge AM, Aung KZ, Dolphin TK, English DR, Giles GG, Guymer RH. Fat consumption and its association with age-related macular degeneration. Arch Ophthalmol 2009; 127:674-80; PMID:19433719; http://dx.doi.org/10.1001/archophthalmol.2009.60.
-
(2009)
Arch Ophthalmol
, vol.127
, pp. 674-680
-
-
Chong, E.W.1
Robman, L.D.2
Simpson, J.A.3
Hodge, A.M.4
Aung, K.Z.5
Dolphin, T.K.6
English, D.R.7
Giles, G.G.8
Guymer, R.H.9
-
96
-
-
79960178230
-
Dietary omega-3 fatty acid and fish intake and incident age-related macular degeneration in women
-
PMID:21402976
-
Christen WG, Schaumberg DA, Glynn RJ, Buring JE. Dietary omega-3 fatty acid and fish intake and incident age-related macular degeneration in women. Arch Ophthalmol 2011; 129:921-9; PMID:21402976; http://dx.doi.org/10.1001/archophthalmol.2011.34.
-
(2011)
Arch Ophthalmol
, vol.129
, pp. 921-929
-
-
Christen, W.G.1
Schaumberg, D.A.2
Glynn, R.J.3
Buring, J.E.4
-
97
-
-
65649127117
-
Dietary fatty acids and the 10-year incidence of age-related macular degeneration: The Blue Mountains Eye Study
-
PMID:19433717
-
Tan JS, Wang JJ, Flood V, Mitchell P. Dietary fatty acids and the 10-year incidence of age-related macular degeneration: the Blue Mountains Eye Study. Arch Ophthalmol 2009; 27:656-65; PMID:19433717; http://dx.doi.org/10.1001/archophthalmol.2009.76.
-
(2009)
Arch Ophthalmol
, vol.27
, pp. 656-665
-
-
Tan, J.S.1
Wang, J.J.2
Flood, V.3
Mitchell, P.4
-
98
-
-
84881144615
-
Nutritional AMDTSG. Oral docosahexaenoic acid in the prevention of exudative age-related macular degeneration: The Nutritional AMD Treatment 2 study
-
PMID:23395546
-
Souied EH, Delcourt C, Querques G, Bassols A, Merle B, Zourdani A, Smith T, Benlian P, Nutritional AMDTSG. Oral docosahexaenoic acid in the prevention of exudative age-related macular degeneration: the Nutritional AMD Treatment 2 study. Ophthalmology 2013; 120:1619-31; PMID:23395546; http://dx.doi.org/10.1016/j.ophtha.2013.01.005.
-
(2013)
Ophthalmology
, vol.120
, pp. 1619-1631
-
-
Souied, E.H.1
Delcourt, C.2
Querques, G.3
Bassols, A.4
Merle, B.5
Zourdani, A.6
Smith, T.7
Benlian, P.8
-
99
-
-
84877734641
-
Lutein C zeaxanthin and omega-3 fatty acids for age-related macular degeneration: The Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial
-
Age-Related Eye Disease Study 2 Research G, PMID:23644932
-
Age-Related Eye Disease Study 2 Research G. Lutein C zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. Jama 2013; 309:2005-15; PMID:23644932; http://dx.doi.org/10.1001/jama.2013.4997.
-
(2013)
Jama
, vol.309
, pp. 2005-2015
-
-
-
100
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
PMID:15461798
-
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 2004; 5:R80; PMID:15461798; http://dx.doi.org/10.1186/gb-2004-5-10-r80.
-
(2004)
Genome Biol
, vol.5
, pp. 80
-
-
Gentleman, R.C.1
Carey, V.J.2
Bates, D.M.3
Bolstad, B.4
Dettling, M.5
Dudoit, S.6
Ellis, B.7
Gautier, L.8
Ge, Y.9
Gentry, J.10
|