Omega-3 free fatty acids suppress macrophage inflammasome activation by inhibiting NF-κB activation and enhancing autophagy

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Williams Bey, Yolanda ^a   Boularan, Cedric ^a   Vural, Ali ^a   Huang, Ning Na ^a   Hwang, Il Young ^a   Shan Shi, Chong ^a   Kehrl, John H ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN; CALCIUM; CRYOPYRIN; DOCOSAHEXAENOIC ACID; G PROTEIN COUPLED RECEPTOR 120; G PROTEIN COUPLED RECEPTOR 40; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; LIGAND; OMEGA 3 FATTY ACID; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; G PROTEIN COUPLED RECEPTOR; LIPOPOLYSACCHARIDE; O3FAR1 PROTEIN, MOUSE; RETINA S ANTIGEN;

ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CALCIUM CELL LEVEL; CONTROLLED STUDY; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INNATE IMMUNITY; MACROPHAGE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; RECEPTOR BINDING; WILD TYPE; ACTIVE TRANSPORT; ANIMAL; BIOSYNTHESIS; BONE MARROW CELL; C57BL MOUSE; CELL NUCLEUS; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HELA CELL LINE; HUMAN; IMMUNOLOGY; INTRACELLULAR SPACE; MACROPHAGE ACTIVATION; METABOLISM; SECRETION (PROCESS);

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ARRESTINS; AUTOPHAGY; BONE MARROW CELLS; CALCIUM; CELL NUCLEUS; DOCOSAHEXAENOIC ACIDS; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; INTRACELLULAR SPACE; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; NF-KAPPA B; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84902673006     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097957     Document Type: Article

References (18)

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