EPA, an omega-3 fatty acid, induces apoptosis in human pancreatic cancer cells: Role of ROS accumulation, caspase-8 activation, and autophagy induction

Journal of Cellular Biochemistry

Volumn 114, Issue 1, 2013, Pages 192-203

  Fukui, Masayuki ^a,b   Kang, Ki Sung ^a,c   Okada, Kazushi ^a   Zhu, Bao Ting ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF THE RYUKYUS   (Japan)

^c Korea Institute of Science and Technology   (South Korea)

Author keywords

APOPTOSIS; AUTOPHAGY; DOCOSAHEXAENOIC ACID; EICOSAPENTAENOIC ACID; OMEGA 3 POLYUNSATURATED FATTY ACIDS; PANCREATIC CANCER

Indexed keywords

CASPASE 8; DOCOSAHEXAENOIC ACID; FISH OIL; ICOSAPENTAENOIC ACID; LINOLEIC ACID; OMEGA 3 FATTY ACID; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVATION; FEEDING; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PANCREAS CANCER; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TRANSMISSION ELECTRON MICROSCOPY; TUMOR VOLUME;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CASPASE 8; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; HUMANS; MICE; MICE, NUDE; OXIDATIVE STRESS; PANCREATIC NEOPLASMS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

AGOUTI PACA; ANIMALIA; MUS MUSCULUS;

EID: 84869392417     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24354     Document Type: Article

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