Quantum dots targeted to the assigned organelle in living cells

Microbiology and Immunology

Volumn 48, Issue 12, 2004, Pages 985-994

  Hoshino, Akiyoshi ^a,b,c   Fujioka, Kouki ^a   Oku, Taisuke ^a,d   Nakamura, Shun ^e   Suga, Masakazu ^a   Yamaguchi, Yukio ^d   Suzuki, Kazuo ^c   Yasuhara, Masato ^b   Yamamoto, Kenji ^a,b  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

Bioimaging; Mitochondria targeting signal; Nanocrystal; Nuclear localizing signal; Quantum dot; Signal peptide

Indexed keywords

NANOPARTICLE; PEPTIDE DERIVATIVE; PROTEIN; QUANTUM DOT;

ANIMAL CELL; CELL NUCLEUS; CELL ORGANELLE; CONTROLLED STUDY; CULTURE MEDIUM; FLUORESCENCE; FLUORESCENT NANOCRYSTAL QUANTUM DOT; IMAGE ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; LUMINESCENCE; MITOCHONDRION; NONHUMAN; PROTEIN LOCALIZATION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 11144326721     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2004.tb03621.x     Document Type: Review

References (41)

1. Aglipay, J.A., Lee, S.W., Okada, S., Fujiuchi, N., Ohtsuka, T., Kwak, J.C., Wang, Y., Johnstone, R.W., Deng, C., Qin, J., and Ouchi, T. 2003. Oncogene 22: 8931-8938.
2. Akerman, M.E., Chan, W.C., Laakkonen, P., Bhatia, S.N., and Ruoslahti, E. 2002. Nanocrystal targeting in vivo. Proc. Natl. Acad. Sci. U.S.A. 99: 12617-12621.
3. Ballou, B., Lagerholm, B.C., Ernst, L.A., Brachez, M.P., and Waggoner, A.S. 2004. Noninvasive imaging of quantum dots in mice. Bioconjugate Chem. 15: 79-86.
4. Brachez, M., Jr., Moronne, M., Gin, P., Weiss, S., and Alivisatos, A.P. 1998. Semiconductor nanocrystals as fluorescent biological labels. Science 281: 2013-2016.
5. Chan, W.C., and Nie, S. 1998. Quantum dot bioconjugates for ultrasensitive nonisotopic detection. Science 281: 2016-2018.
6. Dabboussi, B.O., Rodriguez-Viejo, J., Mikulec, F.V., Hein, J.R., Mattoussi, H., Ober, R., Jensen, K.F., and Bawendi, M.G. 1997. (CdSe)ZnS core-shell quantum dots; synthesis and characterization of size series of highly luminescent nanocrystallites. J. Phys. Chem. 101: 9463-9475.
7. Dubertret, B., Skourides, P., Norris, D.J., Noireaux, V., Brivanlou, A.H., and Libchaber, A. 2002. In vivo imaging of quantum dots encapsulated in phospholipid micelles. Science 298: 1759-1762.
8. Gao, X., Chan, W.C., and Nie, S. 2002. Quantum-dot nanocrystals for ultrasensitive biological labeling and multicolor optical encoding. J. Biomed. Opt. 7: 532-537.
9. Gao, X., Cui, Y., Levenson, R.M., Chung, L.W.K., and Nie, S. 2004. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotechnol. 22: 969-976.
10. Gerion, D., Pinaud, F., Williams, S.C., Parak, W.J., Zanchet, D., Weiss, S., and Alivisatos, A.P. 2001. Synthesis and properties of biocompatible water-soluble silica-coated CdSe/ZnS semiconductor quantum dots. J. Phys. Chem. 105: 8861-8871.
11. Goldman, E.R., Anderson, O.P., Tran, P.T., Mattoussi, H., Charles, P.T., and Mauro, J.M. 2002. Conjugation of luminescent quantum dots with antibodies using an engineered adaptor protein to provide new reagents for fluoroimmunoassays. Anal. Chem. 74: 841-847.
12. Gorlich, D., and Mattaj, I.W. 1996. Nucleocytoplasmic transport. Science 271: 1513-1518.
13. Haggie, P.M., and Verkman, A.S. 2002. Diffusion of tricarboxylic acid cycle enzymes in the mitochondrial matrix in vivo. Evidence for restricted mobility of a multienzyme complex. J. Biol. Chem. 277: 40782-40788.
14. Hanaki, K., Momo, A., Oku, T., Komoto, A., Maenosono, S., Yamaguchi, Y., and Yamamoto, K. 2003. Semiconductor quantum dot/albumin complex is a long-life and highly photostable endosome marker. Biochem. Biophys. Res. Commun. 302: 496-501.
15. Hines, M.A., and Guyot-Sionnest, P. 1996. Synthesis and characterization of strongly luminescing ZnS-capped CdSe nanocrystals. J. Phys. Chem. 100: 468-471.
16. Hoshino, A., Fujioka, K., Oku, T., Suga, M., Sasaki, Y.F., Ohta, T., Yasuhara, M., Suzuki, K., and Yamamoto, K. 2004. Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification. Nano Lett. 4: 2163-2169.
17. Hoshino, A., Hanaki, K., Suzuki, K., and Yamamoto, K. 2004. The applications T-lymphoma labeled with fluorescent quantum dots to cell trafficking markers in a mouse body. Biochem. Biophys. Res. Commun. 314: 46-53.
18. Ishii, D., Kinbara, K., Ishida, Y., Ishii, N., Okochi, M., Yohda, M., and Aida, T. 2003. Chaperonin-mediated stabilization and ATP-triggered release of semiconductor nanoparticles. Nature 423: 628-632.
19. Jaiswal, J.K., Mattoussi, H., Mauro, J.M., and Simon, S.M. 2003. Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nat. Biotechnol. 21: 47-51.
20. Johnson, L.V., Walsh, M.L., and Chen, L.B. 1980. Localization of mitochondria in living cells with rhodamine 123. Proc. Natl. Acad. Sci. U.S.A. 77: 990-994.
21. Kaether, C., and Gerdes, H.H. 1995. Visualization of protein transport along the secretory pathway using green fluorescent protein. FEBS Lett. 369: 267-271.
22. Kaul, Z., Yaguchi, T., Kaul, S.C., Hirano, T., Wadhwa, R., and Taira, K. 2003. Mortalin imaging in normal and cancer cells with quantum dot immuno-conjugates. Cell Res. 13: 503-507.
23. Larson, D.R., Zipfel, W.R., Williams, R.M., Clark, S.W., Bruchez, M.P., Wise, F.W., and Webb, W.W. 2003. Water-soluble quantum dots for multiphoton fluorescence imaging in vivo. Science 300: 1434-1436.
24. Lidke, D.S., Nagy, P., Heintzmann, R., Arndt-Jovin, D.J., Post, J.N., Grecco, H.E., Jares-Erijman, E.A., and Jovin, T.M. 2004. Quantum dot ligands provide new insights into erbB/HER receptor-mediated signal transduction. Nat. Biotechnol. 22: 198-203.
25. Matsushita, M., Tomizawa, K., Moriwaki, A., Li, S.T., Terada, H., and Matsui, H.J. 2001. A high-efficiency protein transduction system demonstrating the role of PKA in long-lasting long-term potentiation. J. Neurosci. 21: 6000-6007.
26. Mattaj, I.W., and Englmeier, L. 1998. Nucleocytoplasmic transport: the soluble phase. Annu. Rev. Biochem. 67: 265-306.
27. Mattoussi, H., Mauro, J.M., Goldman, E.R., Anderson, G.P., Sundar, V.C., Mikulec, F.V., and Bawendi, M.G. 2000. Self-assembly of CdSe-ZnS quantum dot bioconjugates using an engineered recombinant protein. J. Am. Chem. Soc. 122: 12142-12150.
28. Medintz, I.L., Clapp, A.R., Mattoussi, H., Goldman, E.R., Fisher, B., and Mauro, J.M. 2003. Self-assembled nanoscale biosensors based on quantum dot FRET donors. Nat. Mater. 2: 630-639.
29. Osaki, F., Kanamori, T., and Sando, S., Sera, T., and Aoyama, Y. 2004. Quantum dot conjugated sugar ball and its cellular uptake. On the size effects of endocytosis in the subviral region. J. Am. Chem. Soc. 126: 6520-6521.
30. Pinaud, F., King, D., Moore, H.P., and Weiss, S. 2004. Bioactivation and cell targeting of semiconductor CdSe/ZnS nanocrystals with phytochelatin-related peptides. J. Am. Chem. Soc. 126: 6115-6123.
31. Rizzuto, R., Brini, M., Pizzo, P., Murgia, M., and Pozzan, T. 1995. Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells. Curr. Biol. 5: 635-642.
32. Rosenthal, S.J., Tomlinson, I., Adkins, E.M., Schroeter, S., Adams, S., Swafford, L., McBride, J., Wang, Y., DeFelice, L.J., and Blakely, R.D. 2002. Targeting cell surface receptors with ligand-conjugated nanocrystals. J. Am. Chem. Soc. 124: 4586-4594.
33. Shibahara, A., Hoshino, A., Hanaki, K., Suzuki, K., and Yamamoto, K. 2004. On the cyto-toxicity caused by quantum dots. Microbiol. Immunol. 48: 669-675.
34. Shubeita, G.T., Sekatskii, S.K., Dietler, G., Potapova, I., Mews, A., and Basch, T. 2003. Scanning near-field optical microscopy using semiconductor nanocrystals as a local fluorescence and fluorescence resonance energy transfer source. J. Microsc. 210: 274-278.
35. Smith, A.M., Gao, X., and Nie, S. 2004. Quantum-dot nanocrystals for in-vivo molecular and cellular imaging. Photochem. Photobiol. (in press).
36. Su, X.L., and Li, Y. 2004. Quantum dot biolabeling coupled with immunomagnetic separation for detection of Escherichia coli O157:H7. Anal. Chem. 76: 4806-4810.
37. Taguchi, T., Shimura, M., Osawa, Y., Suzuki, Y., Mizoguchi, I., Niino, K., Takaku, F., and Ishizaka, Y. 2004. Nuclear trafficking of macromolecules by an oligopeptide derived from Vpr of human immunodeficiency virus type-1. Biochem. Biophys. Res. Commun. 320: 18-26.
38. Voura, E.B., Jaiswal, J.K., Mattoussi, H., and Simon, S.M. 2004. Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy. Nat. Med. 10: 993-998.
39. Wu, H.Y., Tomizawa, K., Matsushita, M., Lu, Y.F., Li, S.T., and Matsui, H. 2003. Poly-arginine-fused calpastatin peptide, a living cell membrane-permeable and specific inhibitor for calpain. Neurosci. Res. 47: 131-135.
40. Wu, X., Liu, H., Liu, J., Haley, K.N., Treadway, J.A., Larson, J.P., Ge, N., Peale, F., and Bruchez, M.P. 2003. Immunofluorescent labeling of cancer marker Her2 and other cellular targets with semiconductor quantum dots. Nat. Biotechnol. 21: 41-46.
41. Xu, H., Sha, M.Y., Wong, E.Y., Uphoff, J., Xu, Y., Treadway, J.A., Truong, A., O'Brien, E., Asquith, S., Stubbins, M., Spurr, N.K., Lai, E.H., and Mahoney, W. 2003. Multiplexed SNP genotyping using the Qbead system: a quantum dot-encoded microsphere-based assay. Nucleic Acids Res. 31: 43.