The response of macrophages to titanium particles is determined by macrophage polarization

Acta Biomaterialia

Volumn 9, Issue 11, 2013, Pages 9229-9240

  Pajarinen, Jukka ^a,b   Kouri, Vesa Petteri ^b   Jämsen, Eemeli ^a,b   Li, Tian Fang ^c   Mandelin, Jami ^b   Konttinen, Yrjö T ^a,b,d  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^d ORTON ORTHOPAEDIC HOSPITAL   (Finland)

Author keywords

Foreign body response; Joint replacement; Macrophage; Titanium; Wear debris

Indexed keywords

ARTHROPLASTY; GENES; JOINT PROSTHESES; POLARIZATION; TITANIUM;

ASEPTIC LOOSENING; CYTOKINES; FOREIGN BODIES; FOREIGN BODY RESPONSE; JOINT REPLACEMENT; MICROENVIRONMENTS; PARTICLE CHARACTERISTICS; TITANIUM PARTICLES; TOTAL JOINT REPLACEMENT; WEAR DEBRIS;

MACROPHAGES;

ACTIVATING TRANSCRIPTION FACTOR; CALCIUM BINDING PROTEIN; CATHEPSIN K; CHEMOKINE RECEPTOR CXCR4; COLONY STIMULATING FACTOR 1; CXCL1 CHEMOKINE; CXCL11 CHEMOKINE; CXCL2 CHEMOKINE; CXCL3 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HERPESVIRUS ENTRY MEDIATOR LIGAND; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 2; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 7; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 3; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PROSTAGLANDIN SYNTHASE; PROTEIN C JUN; SECONDARY LYMPHOID TISSUE CHEMOKINE; THROMBOSPONDIN 1; TITANIUM; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BIOFILM; CELL DIFFERENTIATION; CELL MOTILITY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; FOREIGN BODY REACTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMAGE ANALYSIS; MACROPHAGE; MACROPHAGE CULTURE; MICROARRAY ANALYSIS; MONOCYTE; OSTEOLYSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PHAGOCYTOSIS; PHASE CONTRAST MICROSCOPY; POLARIZATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SIGNAL TRANSDUCTION; UPREGULATION;

BACTERIA (MICROORGANISMS);

FOREIGN BODY RESPONSE; JOINT REPLACEMENT; MACROPHAGE; TITANIUM; WEAR DEBRIS;

ADULT; CELL DEATH; CELL DIFFERENTIATION; CELL MOVEMENT; CELL POLARITY; CYTOKINES; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE ONTOLOGY; HUMANS; MACROPHAGES; MALE; MONOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARTICULATE MATTER; PHAGOCYTOSIS; PROTEIN ARRAY ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TITANIUM; UP-REGULATION; YOUNG ADULT;

EID: 84885037820     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.06.027     Document Type: Article

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