메뉴 건너뛰기




Volumn 8, Issue 6, 2013, Pages 969-981

Nanoparticles and the blood coagulation system. Part II: Safety concerns

Author keywords

coagulopathy; disseminated intravascular coagulation; endothelial cell; leukocyte; nanoparticle; procoagulant activity platelet; thrombosis

Indexed keywords

BLOOD CLOTTING FACTOR; DENDRIMER; GOLD NANOPARTICLE; IRON OXIDE; LIPOSOME; QUANTUM DOT; SILICON DIOXIDE; SILVER NANOPARTICLE;

EID: 84878691367     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.13.49     Document Type: Review
Times cited : (178)

References (103)
  • 1
    • 84877676645 scopus 로고    scopus 로고
    • Nanoparticles and the blood coagulation system. Part I: Benefits of nanotechnology
    • Ilinskaya AN, Dobrovolskaia MA. Nanoparticles and the blood coagulation system. Part I: benefits of nanotechnology. Nanomedicine (Lond.) 8(5), 773-784 (2013).
    • (2013) Nanomedicine (Lond.) , vol.8 , Issue.5 , pp. 773-784
    • Ilinskaya, A.N.1    Dobrovolskaia, M.A.2
  • 2
    • 77953229216 scopus 로고    scopus 로고
    • Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association
    • Brook RD, Rajagopalan S, Pope CA 3rd et al. Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association. Circulation 121(21), 2331-2378 (2010).
    • (2010) Circulation , vol.121 , Issue.21 , pp. 2331-2378
    • Brook, R.D.1    Rajagopalan, S.2    Pope Iii, C.A.3
  • 3
    • 32444433552 scopus 로고    scopus 로고
    • Air pollution and markers of inflammation and coagulation in patients with coronary heart disease
    • Rückerl R, Ibald-Mulli A, Koenig W et al. Air pollution and markers of inflammation and coagulation in patients with coronary heart disease. Am. J. Respir. Crit. Care Med. 173(4), 432-441 (2006).
    • (2006) Am. J. Respir. Crit. Care Med. , vol.173 , Issue.4 , pp. 432-441
    • Rückerl, R.1    Ibald-Mulli, A.2    Koenig, W.3
  • 4
    • 43549115503 scopus 로고    scopus 로고
    • Exposure to particulate air pollution and risk of deep vein thrombosis
    • Baccarelli A, Martinelli I, Zanobetti A et al. Exposure to particulate air pollution and risk of deep vein thrombosis. Arch. Intern. Med. 168(9), 920-927 (2008).
    • (2008) Arch. Intern. Med. , vol.168 , Issue.9 , pp. 920-927
    • Baccarelli, A.1    Martinelli, I.2    Zanobetti, A.3
  • 5
    • 0036917225 scopus 로고    scopus 로고
    • Cardiovascular effects associated with air pollution: Potential mechanisms and methods of testing
    • Utell MJ, Frampton MW, Zareba W, Devlin RB, Cascio WE. Cardiovascular effects associated with air pollution: potential mechanisms and methods of testing. Inhal. Toxicol. 14(12), 1231-1247 (2002).
    • (2002) Inhal. Toxicol. , vol.14 , Issue.12 , pp. 1231-1247
    • Utell, M.J.1    Frampton, M.W.2    Zareba, W.3    Devlin, R.B.4    Cascio, W.E.5
  • 6
    • 50449098285 scopus 로고    scopus 로고
    • Mechanisms of thrombus formation
    • Furie B, Furie BC. Mechanisms of thrombus formation. N. Engl. J. Med. 359(9), 938-949 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , Issue.9 , pp. 938-949
    • Furie, B.1    Furie, B.C.2
  • 7
    • 84867528048 scopus 로고    scopus 로고
    • Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles
    • Greish K, Thiagarajan G, Herd H et al. Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles. Nanotoxicology 6(7), 713-723. (2011).
    • (2011) Nanotoxicology , vol.6 , Issue.7 , pp. 713-723
    • Greish, K.1    Thiagarajan, G.2    Herd, H.3
  • 8
    • 84855606424 scopus 로고    scopus 로고
    • Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure
    • Nabeshi H, Yoshikawa T, Matsuyama K et al. Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure. Nanotechnology 23(4), 045101 (2012).
    • (2012) Nanotechnology , vol.23 , Issue.4 , pp. 045101
    • Nabeshi, H.1    Yoshikawa, T.2    Matsuyama, K.3
  • 9
    • 27744508593 scopus 로고    scopus 로고
    • Nanoparticle-induced platelet aggregation and vascular thrombosis
    • Radomski A, Jurasz P, Alonso-Escolano D et al. Nanoparticle-induced platelet aggregation and vascular thrombosis. Br. J. Pharmacol. 146(6), 882-893 (2005).
    • (2005) Br. J. Pharmacol. , vol.146 , Issue.6 , pp. 882-893
    • Radomski, A.1    Jurasz, P.2    Alonso-Escolano, D.3
  • 11
    • 67649491055 scopus 로고    scopus 로고
    • Understanding biophysicochemical interactions at the nano-bio interface
    • Nel AE, Madler L, Velegol D et al. Understanding biophysicochemical interactions at the nano-bio interface. Nat. Mater. 8(7), 543-557 (2009).
    • (2009) Nat. Mater. , vol.8 , Issue.7 , pp. 543-557
    • Nel, A.E.1    Madler, L.2    Velegol, D.3
  • 12
    • 80053328840 scopus 로고    scopus 로고
    • Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: A comprehensive quantitative proteomic analysis
    • Tenzer S, Docter D, Rosfa S et al. Nanoparticle size is a critical physicochemical determinant of the human blood plasma corona: a comprehensive quantitative proteomic analysis. ACS Nano 5(9), 7155-7167 (2011).
    • (2011) ACS Nano , vol.5 , Issue.9 , pp. 7155-7167
    • Tenzer, S.1    Docter, D.2    Rosfa, S.3
  • 13
    • 55749091647 scopus 로고    scopus 로고
    • Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts
    • Lundqvist M, Stigler J, Elia G, Lynch I, Cedervall T, Dawson KA. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc. Natl Acad. Sci. USA 105(38), 14265-14270 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , Issue.38 , pp. 14265-14270
    • Lundqvist, M.1    Stigler, J.2    Elia, G.3    Lynch, I.4    Cedervall, T.5    Dawson, K.A.6
  • 14
    • 65749117793 scopus 로고    scopus 로고
    • Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy
    • Aggarwal P, Hall JB, McLeland CB, Dobrovolskaia MA, McNeil SE. Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy. Adv. Drug Deliv. Rev. 61(6), 428-437 (2009).
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , Issue.6 , pp. 428-437
    • Aggarwal, P.1    Hall, J.B.2    McLeland, C.B.3    Dobrovolskaia, M.A.4    McNeil, S.E.5
  • 15
    • 67651175853 scopus 로고    scopus 로고
    • Blood coagulation on biomaterials requires the combination of distinct activation processes
    • Sperling C, Fischer M, Maitz MF, Werner C. Blood coagulation on biomaterials requires the combination of distinct activation processes. Biomaterials 30(27), 4447-4456 (2009).
    • (2009) Biomaterials , vol.30 , Issue.27 , pp. 4447-4456
    • Sperling, C.1    Fischer, M.2    Maitz, M.F.3    Werner, C.4
  • 16
    • 84864083902 scopus 로고    scopus 로고
    • Polystyrene nanoparticles affecting blood coagulation
    • Oslakovic C, Cedervall T, Linse S, Dahlback B. Polystyrene nanoparticles affecting blood coagulation. Nanomedicine 8(6), 981-986 (2012).
    • (2012) Nanomedicine , vol.8 , Issue.6 , pp. 981-986
    • Oslakovic, C.1    Cedervall, T.2    Linse, S.3    Dahlback, B.4
  • 17
    • 0034005436 scopus 로고    scopus 로고
    • Dendrimers: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I labelled polyamidoamine dendrimers in vivo
    • Malik N, Wiwattanapatapee R, Klopsch R et al. Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I labelled polyamidoamine dendrimers in vivo. J. Control. Release 65(1-2), 133-148 (2000).
    • (2000) J. Control. Release , vol.65 , Issue.1-2 , pp. 133-148
    • Malik, N.1    Wiwattanapatapee, R.2    Klopsch, R.3
  • 20
    • 84858042094 scopus 로고    scopus 로고
    • Nanoparticle size and surface charge determine effects of PAMAM dendrimers on human platelets in vitro
    • Dobrovolskaia MA, Patri AK, Simak J et al. Nanoparticle size and surface charge determine effects of PAMAM dendrimers on human platelets in vitro. Mol. Pharm. 9(3), 382-393 (2011).
    • (2011) Mol. Pharm. , vol.9 , Issue.3 , pp. 382-393
    • Dobrovolskaia, M.A.1    Patri, A.K.2    Simak, J.3
  • 21
    • 84862001474 scopus 로고    scopus 로고
    • Cationic PAMAM dendrimers disrupt key platelet functions
    • Jones CF, Campbell RA, Franks Z et al. Cationic PAMAM dendrimers disrupt key platelet functions. Mol. Pharm. 9(6), 1599-1611 (2012).
    • (2012) Mol. Pharm. , vol.9 , Issue.6 , pp. 1599-1611
    • Jones, C.F.1    Campbell, R.A.2    Franks, Z.3
  • 22
    • 79952371250 scopus 로고    scopus 로고
    • Aggravating impact of nanoparticles on immune-mediated pulmonary inflammation
    • Inoue K, Takano H. Aggravating impact of nanoparticles on immune-mediated pulmonary inflammation. ScientificWorldJournal 11, 382-390 (2011).
    • (2011) ScientificWorldJournal , vol.11 , pp. 382-390
    • Inoue, K.1    Takano, H.2
  • 24
    • 79961050714 scopus 로고    scopus 로고
    • Promoting effects of nanoparticles/ materials on sensitive lung inflammatory diseases
    • Inoue K. Promoting effects of nanoparticles/ materials on sensitive lung inflammatory diseases. Environ. Health Prev. Med. 16(3), 139-143 (2011).
    • (2011) Environ. Health Prev. Med. , vol.16 , Issue.3 , pp. 139-143
    • Inoue, K.1
  • 25
    • 78751699054 scopus 로고    scopus 로고
    • Surface derivatization state of polystyrene latex nanoparticles determines both their potency and their mechanism of causing human platelet aggregation in vitro
    • McGuinnes C, Duffin R, Brown S et al. Surface derivatization state of polystyrene latex nanoparticles determines both their potency and their mechanism of causing human platelet aggregation in vitro. Toxicol. Sci. 119(2), 359-368 (2011).
    • (2011) Toxicol. Sci. , vol.119 , Issue.2 , pp. 359-368
    • McGuinnes, C.1    Duffin, R.2    Brown, S.3
  • 26
    • 0020630443 scopus 로고
    • Interactions of conventional or photopolymerized liposomes with platelets in vitro
    • Juliano RL, Hsu MJ, Peterson D, Regen SL, Singh A. Interactions of conventional or photopolymerized liposomes with platelets in vitro. Exp. Cell Res. 146(2), 422-427 (1983).
    • (1983) Exp. Cell Res. , vol.146 , Issue.2 , pp. 422-427
    • Juliano, R.L.1    Hsu, M.J.2    Peterson, D.3    Regen, S.L.4    Singh, A.5
  • 27
    • 27144525821 scopus 로고    scopus 로고
    • Blood compatibility of cetyl alcohol/polysorbate-based nanoparticles
    • Koziara JM, Oh JJ, Akers WS, Ferraris SP, Mumper RJ. Blood compatibility of cetyl alcohol/polysorbate-based nanoparticles. Pharm. Res. 22(11), 1821-1828 (2005).
    • (2005) Pharm. Res. , vol.22 , Issue.11 , pp. 1821-1828
    • Koziara, J.M.1    Oh, J.J.2    Akers, W.S.3    Ferraris, S.P.4    Mumper, R.J.5
  • 28
    • 0024601847 scopus 로고
    • Assessment of thrombogenic potential of liposomes
    • Zbinden G, Wunderli-Allenspach H, Grimm L. Assessment of thrombogenic potential of liposomes. Toxicology 54(3), 273-280 (1989).
    • (1989) Toxicology , vol.54 , Issue.3 , pp. 273-280
    • Zbinden, G.1    Wunderli-Allenspach, H.2    Grimm, L.3
  • 32
    • 0030570523 scopus 로고    scopus 로고
    • Interaction of RGD liposomes with platelets
    • Nishiya T, Sloan S. Interaction of RGD liposomes with platelets. Biochem. Biophys. Res. Commun. 224(1), 242-245 (1996).
    • (1996) Biochem. Biophys. Res. Commun. , vol.224 , Issue.1 , pp. 242-245
    • Nishiya, T.1    Sloan, S.2
  • 34
    • 48549093418 scopus 로고    scopus 로고
    • Importance of the liposomal cationic lipid content and type in tumor vascular targeting: Physicochemical characterization and in vitro studies using human primary and transformed endothelial cells
    • Dabbas S, Kaushik RR, Dandamudi S, Kuesters GM, Campbell RB. Importance of the liposomal cationic lipid content and type in tumor vascular targeting: physicochemical characterization and in vitro studies using human primary and transformed endothelial cells. Endothelium 15(4), 189-201 (2008).
    • (2008) Endothelium , vol.15 , Issue.4 , pp. 189-201
    • Dabbas, S.1    Kaushik, R.R.2    Dandamudi, S.3    Kuesters, G.M.4    Campbell, R.B.5
  • 35
    • 0036897324 scopus 로고    scopus 로고
    • Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors
    • Campbell RB, Fukumura D, Brown EB et al. Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. Cancer Res. 62(23), 6831-6836 (2002).
    • (2002) Cancer Res , vol.62 , Issue.23 , pp. 6831-6836
    • Campbell, R.B.1    Fukumura, D.2    Brown, E.B.3
  • 36
    • 0037846456 scopus 로고    scopus 로고
    • Effect of the surface charge of liposomes on their uptake by angiogenic tumor vessels
    • Krasnici S, Werner A, Eichhorn ME et al. Effect of the surface charge of liposomes on their uptake by angiogenic tumor vessels. Int. J. Cancer 105(4), 561-567 (2003).
    • (2003) Int. J. Cancer , vol.105 , Issue.4 , pp. 561-567
    • Krasnici, S.1    Werner, A.2    Eichhorn, M.E.3
  • 38
    • 0021994233 scopus 로고
    • Present status of clinical studies of Fluosol-DA (20%) in Japan
    • Mitsuno T, Ohyanagi H. Present status of clinical studies of Fluosol-DA (20%) in Japan. Int. Anesthesiol. Clin. 23(1), 169-184 (1985).
    • (1985) Int. Anesthesiol. Clin. , vol.23 , Issue.1 , pp. 169-184
    • Mitsuno, T.1    Ohyanagi, H.2
  • 39
    • 0019985544 scopus 로고
    • Activation of plasma complement by perfluorocarbon artificial blood: Probable mechanism of adverse pulmonary reactions in treated patients and rationale for corticosteroids prophylaxis
    • Vercellotti GM, Hammerschmidt DE, Craddock PR, Jacob HS. Activation of plasma complement by perfluorocarbon artificial blood: probable mechanism of adverse pulmonary reactions in treated patients and rationale for corticosteroids prophylaxis. Blood 59(6), 1299-1304 (1982).
    • (1982) Blood , vol.59 , Issue.6 , pp. 1299-1304
    • Vercellotti, G.M.1    Hammerschmidt, D.E.2    Craddock, P.R.3    Jacob, H.S.4
  • 40
    • 0034087593 scopus 로고    scopus 로고
    • A second-generation blood substitute (perfluorodichlorooctane emulsion) generates spurious elevations in platelet counts from automated hematology analyzers
    • Cuignet OY, Wood BL, Chandler WL, Spiess BD. A second-generation blood substitute (perfluorodichlorooctane emulsion) generates spurious elevations in platelet counts from automated hematology analyzers. Anesth. Analg. 90(3), 517-522 (2000).
    • (2000) Anesth. Analg. , vol.90 , Issue.3 , pp. 517-522
    • Cuignet, O.Y.1    Wood, B.L.2    Chandler, W.L.3    Spiess, B.D.4
  • 41
    • 49249120915 scopus 로고    scopus 로고
    • Spurious propofol-induced coagulopathy in a patient with hepatic rupture
    • Thomson H, Ali A, Harper NJ. Spurious propofol-induced coagulopathy in a patient with hepatic rupture. Anaesthesia 63(9), 1024-1025 (2008).
    • (2008) Anaesthesia , vol.63 , Issue.9 , pp. 1024-1025
    • Thomson, H.1    Ali, A.2    Harper, N.J.3
  • 43
    • 42949125475 scopus 로고    scopus 로고
    • Experimental exposure to wood smoke: Effects on airway inflammation and oxidative stress
    • Barregard L, Sallsten G, Andersson L et al. Experimental exposure to wood smoke: effects on airway inflammation and oxidative stress. Occup. Environ. Med. 65(5), 319-324 (2008).
    • (2008) Occup. Environ. Med. , vol.65 , Issue.5 , pp. 319-324
    • Barregard, L.1    Sallsten, G.2    Andersson, L.3
  • 44
    • 1842767079 scopus 로고    scopus 로고
    • Possible mechanisms of the cardiovascular effects of inhaled particles: Systemic translocation and prothrombotic effects
    • Nemmar A, Hoylaerts MF, Hoet PH, Nemery B. Possible mechanisms of the cardiovascular effects of inhaled particles: systemic translocation and prothrombotic effects. Toxicol. Lett. 149(1-3), 243-253 (2004).
    • (2004) Toxicol. Lett. , vol.149 , Issue.1-3 , pp. 243-253
    • Nemmar, A.1    Hoylaerts, M.F.2    Hoet, P.H.3    Nemery, B.4
  • 45
    • 80051950685 scopus 로고    scopus 로고
    • Pulmonary biocompatibility assessment of inhaled single-wall and multiwall carbon nanotubes in BALB/c mice
    • Ravichandran P, Baluchamy S, Gopikrishnan R et al. Pulmonary biocompatibility assessment of inhaled single-wall and multiwall carbon nanotubes in BALB/c mice. J. Biol. Chem. 286(34), 29725-29733 (2011).
    • (2011) J. Biol. Chem. , vol.286 , Issue.34 , pp. 29725-29733
    • Ravichandran, P.1    Baluchamy, S.2    Gopikrishnan, R.3
  • 46
    • 41549129392 scopus 로고    scopus 로고
    • The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles
    • Li N, Xia T, Nel AE. The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. Free Radic. Biol. Med. 44(9), 1689-1699 (2008).
    • (2008) Free Radic. Biol. Med. , vol.44 , Issue.9 , pp. 1689-1699
    • Li, N.1    Xia, T.2    Nel, A.E.3
  • 47
    • 27144533136 scopus 로고    scopus 로고
    • Diesel exhaust activates redox-sensitive transcription factors and kinases in human airways
    • Pourazar J, Mudway IS, Samet JM et al. Diesel exhaust activates redox-sensitive transcription factors and kinases in human airways. Am. J. Physiol. Lung Cell. Mol. Physiol. 289(5), L724-L730 (2005).
    • (2005) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.289 , Issue.5
    • Pourazar, J.1    Mudway, I.S.2    Samet, J.M.3
  • 48
    • 0032985046 scopus 로고    scopus 로고
    • Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers
    • Salvi S, Blomberg A, Rudell B et al. Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers. Am. J. Respir. Crit. Care Med. 159(3), 702-709 (1999).
    • (1999) Am. J. Respir. Crit. Care Med. , vol.159 , Issue.3 , pp. 702-709
    • Salvi, S.1    Blomberg, A.2    Rudell, B.3
  • 49
    • 0034016108 scopus 로고    scopus 로고
    • Acute exposure to diesel exhaust increases IL 8 and GRO-alpha production in healthy human airways
    • Salvi SS, Nordenhall C, Blomberg A et al. Acute exposure to diesel exhaust increases IL 8 and GRO-alpha production in healthy human airways. Am. J. Respir. Crit. Care Med. 161(2 Pt 1), 550-557 (2000).
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , Issue.2 PART 1 , pp. 550-557
    • Salvi, S.S.1    Nordenhall, C.2    Blomberg, A.3
  • 50
    • 0043011674 scopus 로고    scopus 로고
    • Involvement of reactive oxygen species in the metabolic pathways triggered by diesel exhaust particles in human airway epithelial cells
    • Baulig A, Garlatti M, Bonvallot V et al. Involvement of reactive oxygen species in the metabolic pathways triggered by diesel exhaust particles in human airway epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 285(3), L671-L679 (2003).
    • (2003) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.285 , Issue.3
    • Baulig, A.1    Garlatti, M.2    Bonvallot, V.3
  • 51
    • 33846585546 scopus 로고    scopus 로고
    • Particulate matter in the environment: Pulmonary and cardiovascular effects
    • Alfaro-Moreno E, Nawrot TS, Nemmar A, Nemery B. Particulate matter in the environment: pulmonary and cardiovascular effects. Curr. Opin. Pulm. Med. 13(2), 98-106 (2007).
    • (2007) Curr. Opin. Pulm. Med. , vol.13 , Issue.2 , pp. 98-106
    • Alfaro-Moreno, E.1    Nawrot, T.S.2    Nemmar, A.3    Nemery, B.4
  • 52
    • 61649085299 scopus 로고    scopus 로고
    • Cross-talk between lung and systemic circulation during carbon nanotube respiratory exposure. Potential biomarkers
    • Erdely A, Hulderman T, Salmen R et al. Cross-talk between lung and systemic circulation during carbon nanotube respiratory exposure. Potential biomarkers. Nano Lett. 9(1), 36-43 (2009).
    • (2009) Nano Lett , vol.9 , Issue.1 , pp. 36-43
    • Erdely, A.1    Hulderman, T.2    Salmen, R.3
  • 53
    • 77954403383 scopus 로고    scopus 로고
    • Disseminated intravascular coagulation in infectious disease
    • Levi M, Schultz M, van der Poll T. Disseminated intravascular coagulation in infectious disease. Semin. Thromb. Hemost. 36(4), 367-377 (2010).
    • (2010) Semin. Thromb. Hemost. , vol.36 , Issue.4 , pp. 367-377
    • Levi, M.1    Schultz, M.2    Van Der Poll, T.3
  • 54
    • 23744470215 scopus 로고    scopus 로고
    • Association of criteria pollutants with plasma hemostatic/inflammatory markers: A population-based study
    • Liao D, Heiss G, Chinchilli VM et al. Association of criteria pollutants with plasma hemostatic/inflammatory markers: a population-based study. J. Expo. Anal. Environ. Epidemiol. 15(4), 319-328 (2005).
    • (2005) J. Expo. Anal. Environ. Epidemiol. , vol.15 , Issue.4 , pp. 319-328
    • Liao, D.1    Heiss, G.2    Chinchilli, V.M.3
  • 55
    • 0348241415 scopus 로고    scopus 로고
    • Exposure to concentrated ambient air particles alters hematologic indices in humans
    • Ghio AJ, Hall A, Bassett MA, Cascio WE, Devlin RB. Exposure to concentrated ambient air particles alters hematologic indices in humans. Inhal. Toxicol. 15(14), 1465-1478 (2003).
    • (2003) Inhal. Toxicol. , vol.15 , Issue.14 , pp. 1465-1478
    • Ghio, A.J.1    Hall, A.2    Bassett, M.A.3    Cascio, W.E.4    Devlin, R.B.5
  • 56
    • 0033229884 scopus 로고    scopus 로고
    • Inflammatory effect of intratracheal instillation of ultrafine particles in the rabbit: Role of C fiber and mast cells
    • Nemmar A, Delaunois A, Nemery B et al. Inflammatory effect of intratracheal instillation of ultrafine particles in the rabbit: role of C fiber and mast cells. Toxicol. Appl. Pharmacol. 160(3), 250-261 (1999).
    • (1999) Toxicol. Appl. Pharmacol. , vol.160 , Issue.3 , pp. 250-261
    • Nemmar, A.1    Delaunois, A.2    Nemery, B.3
  • 57
    • 0017573437 scopus 로고
    • A microanalytic study of particles transport across the alveoli: Role of blood platelets
    • Berry JP, Arnoux B, Stanislas G, Galle P, Chretien J. A microanalytic study of particles transport across the alveoli: role of blood platelets. Biomedicine 27(9-10), 354-357 (1977).
    • (1977) Biomedicine , vol.27 , Issue.9-10 , pp. 354-357
    • Berry, J.P.1    Arnoux, B.2    Stanislas, G.3    Galle, P.4    Chretien, J.5
  • 58
    • 0037192333 scopus 로고    scopus 로고
    • Passage of inhaled particles into the blood circulation in humans
    • Nemmar A, Hoet PH, Vanquickenborne B et al. Passage of inhaled particles into the blood circulation in humans. Circulation 105(4), 411-414 (2002).
    • (2002) Circulation , vol.105 , Issue.4 , pp. 411-414
    • Nemmar, A.1    Hoet, P.H.2    Vanquickenborne, B.3
  • 59
    • 32444451791 scopus 로고    scopus 로고
    • Do inhaled carbon nanoparticles translocate directly into the circulation in humans?
    • Mills NL, Amin N, Robinson SD et al. Do inhaled carbon nanoparticles translocate directly into the circulation in humans? Am. J. Respir. Crit. Care Med. 173(4), 426-431 (2006).
    • (2006) Am. J. Respir. Crit. Care Med. , vol.173 , Issue.4 , pp. 426-431
    • Mills, N.L.1    Amin, N.2    Robinson, S.D.3
  • 60
    • 0037418167 scopus 로고    scopus 로고
    • Diesel exhaust particles in lung acutely enhance experimental peripheral thrombosis
    • Nemmar A, Hoet PH, Dinsdale D, Vermylen J, Hoylaerts MF, Nemery B. Diesel exhaust particles in lung acutely enhance experimental peripheral thrombosis. Circulation 107(8), 1202-1208 (2003).
    • (2003) Circulation , vol.107 , Issue.8 , pp. 1202-1208
    • Nemmar, A.1    Hoet, P.H.2    Dinsdale, D.3    Vermylen, J.4    Hoylaerts, M.F.5    Nemery, B.6
  • 61
    • 26944500505 scopus 로고    scopus 로고
    • Pulmonary exposure to diesel exhaust particles induces airway inflammation and cytokine expression in NC/Nga mice
    • Inoue K, Takano H, Yanagisawa R, Ichinose T, Shimada A, Yoshikawa T. Pulmonary exposure to diesel exhaust particles induces airway inflammation and cytokine expression in NC/Nga mice. Arch. Toxicol. 79(10), 595-599 (2005).
    • (2005) Arch. Toxicol. , vol.79 , Issue.10 , pp. 595-599
    • Inoue, K.1    Takano, H.2    Yanagisawa, R.3    Ichinose, T.4    Shimada, A.5    Yoshikawa, T.6
  • 62
    • 20544461398 scopus 로고    scopus 로고
    • The rat ear vein model for investigating in vivo thrombogenicity of ultrafine particles (UFP)
    • Silva VM, Corson N, Elder A, Oberdorster G. The rat ear vein model for investigating in vivo thrombogenicity of ultrafine particles (UFP). Toxicol. Sci. 85(2), 983-989 (2005).
    • (2005) Toxicol. Sci. , vol.85 , Issue.2 , pp. 983-989
    • Silva, V.M.1    Corson, N.2    Elder, A.3    Oberdorster, G.4
  • 63
    • 1542726626 scopus 로고    scopus 로고
    • Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation
    • Lam CW, James JT, McCluskey R, Hunter RL. Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicol. Sci. 77(1), 126-134 (2004).
    • (2004) Toxicol. Sci. , vol.77 , Issue.1 , pp. 126-134
    • Lam, C.W.1    James, J.T.2    McCluskey, R.3    Hunter, R.L.4
  • 65
    • 24944566939 scopus 로고    scopus 로고
    • Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice
    • Shvedova AA, Kisin ER, Mercer R et al. Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. Am. J. Physiol. Lung Cell. Mol. Physiol. 289(5), L698-L708 (2005).
    • (2005) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.289 , Issue.5
    • Shvedova, A.A.1    Kisin, E.R.2    Mercer, R.3
  • 66
    • 77949917704 scopus 로고    scopus 로고
    • Single-walled carbon nanotubes activate platelets and accelerate thrombus formation in the microcirculation
    • Bihari P, Holzer M, Praetner M et al. Single-walled carbon nanotubes activate platelets and accelerate thrombus formation in the microcirculation. Toxicology 269(2-3), 148-154 (2010).
    • (2010) Toxicology , vol.269 , Issue.2-3 , pp. 148-154
    • Bihari, P.1    Holzer, M.2    Praetner, M.3
  • 67
    • 70350017968 scopus 로고    scopus 로고
    • Carbon nanotubes activate blood platelets by inducing extracellular Ca2+ influx sensitive to calcium entry inhibitors
    • Semberova J, De Paoli Lacerda SH, Simakova O, Holada K, Gelderman MP, Simak J. Carbon nanotubes activate blood platelets by inducing extracellular Ca2+ influx sensitive to calcium entry inhibitors. Nano Lett. 9(9), 3312-3317 (2009).
    • (2009) Nano Lett , vol.9 , Issue.9 , pp. 3312-3317
    • Semberova, J.1    De Paoli Lacerda, S.H.2    Simakova, O.3    Holada, K.4    Gelderman, M.P.5    Simak, J.6
  • 68
    • 79961088119 scopus 로고    scopus 로고
    • Carbon nanotubes activate store-operated calcium entry in human blood platelets
    • Lacerda SH, Semberova J, Holada K, Simakova O, Hudson SD, Simak J. Carbon nanotubes activate store-operated calcium entry in human blood platelets. ACS Nano 5(7), 5808-5813 (2011).
    • (2011) ACS Nano , vol.5 , Issue.7 , pp. 5808-5813
    • Lacerda, S.H.1    Semberova, J.2    Holada, K.3    Simakova, O.4    Hudson, S.D.5    Simak, J.6
  • 69
    • 77955044118 scopus 로고    scopus 로고
    • Platelet adhesion and fibrinogen deposition in murine microvessels upon inhalation of nanosized carbon particles
    • Khandoga A, Stoeger T, Khandoga AG et al. Platelet adhesion and fibrinogen deposition in murine microvessels upon inhalation of nanosized carbon particles. J. Thromb. Haemost. 8(7), 1632-1640 (2010).
    • (2010) J. Thromb. Haemost. , vol.8 , Issue.7 , pp. 1632-1640
    • Khandoga, A.1    Stoeger, T.2    Khandoga, A.G.3
  • 70
    • 1642364266 scopus 로고    scopus 로고
    • Ultrafine particles exert prothrombotic but not inflammatory effects on the hepatic microcirculation in healthy mice in vivo
    • Khandoga A, Stampfl A, Takenaka S et al. Ultrafine particles exert prothrombotic but not inflammatory effects on the hepatic microcirculation in healthy mice in vivo. Circulation 109(10), 1320-1325 (2004).
    • (2004) Circulation , vol.109 , Issue.10 , pp. 1320-1325
    • Khandoga, A.1    Stampfl, A.2    Takenaka, S.3
  • 71
    • 79959956905 scopus 로고    scopus 로고
    • Determinants of the thrombogenic potential of multiwalled carbon nanotubes
    • Burke AR, Singh RN, Carroll DL et al. Determinants of the thrombogenic potential of multiwalled carbon nanotubes. Biomaterials 32(26), 5970-5978 (2011).
    • (2011) Biomaterials , vol.32 , Issue.26 , pp. 5970-5978
    • Burke, A.R.1    Singh, R.N.2    Carroll, D.L.3
  • 73
    • 29644439882 scopus 로고    scopus 로고
    • Mechanisms underlying nano-sized air-pollution-mediated progression of atherosclerosis: Carbon black causes cytotoxic injury/inflammation and inhibits cell growth in vascular endothelial cells
    • Yamawaki H, Iwai N. Mechanisms underlying nano-sized air-pollution- mediated progression of atherosclerosis: carbon black causes cytotoxic injury/inflammation and inhibits cell growth in vascular endothelial cells. Circ. J. 70(1), 129-140 (2006).
    • (2006) Circ. J. , vol.70 , Issue.1 , pp. 129-140
    • Yamawaki, H.1    Iwai, N.2
  • 74
    • 33748329694 scopus 로고    scopus 로고
    • The importance of an endotoxin-free environment during the production of nanoparticles used in medical applications
    • Vallhov H, Qin J, Johansson SM et al. The importance of an endotoxin-free environment during the production of nanoparticles used in medical applications. Nano Lett. 6(8), 1682-1686 (2006).
    • (2006) Nano Lett , vol.6 , Issue.8 , pp. 1682-1686
    • Vallhov, H.1    Qin, J.2    Johansson, S.M.3
  • 75
    • 33845410139 scopus 로고    scopus 로고
    • Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants
    • Pulskamp K, Diabate S, Krug HF. Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants. Toxicol. Lett. 168(1), 58-74 (2007).
    • (2007) Toxicol. Lett. , vol.168 , Issue.1 , pp. 58-74
    • Pulskamp, K.1    Diabate, S.2    Krug, H.F.3
  • 77
    • 58149340533 scopus 로고    scopus 로고
    • Acute toxicity and prothrombotic effects of quantum dots: Impact of surface charge
    • Geys J, Nemmar A, Verbeken E et al. Acute toxicity and prothrombotic effects of quantum dots: impact of surface charge. Environ. Health Perspect. 116(12), 1607-1613 (2008).
    • (2008) Environ. Health Perspect. , vol.116 , Issue.12 , pp. 1607-1613
    • Geys, J.1    Nemmar, A.2    Verbeken, E.3
  • 78
    • 77749315431 scopus 로고    scopus 로고
    • Pulmonary thrombosis in the mouse following intravenous administration of quantum dot-labeled mesenchymal cells
    • Ramot Y, Steiner M, Morad V et al. Pulmonary thrombosis in the mouse following intravenous administration of quantum dot-labeled mesenchymal cells. Nanotoxicology 4(1), 98-105 (2010).
    • (2010) Nanotoxicology , vol.4 , Issue.1 , pp. 98-105
    • Ramot, Y.1    Steiner, M.2    Morad, V.3
  • 79
    • 79952314659 scopus 로고    scopus 로고
    • An in vitro study of vascular endothelial toxicity of CdTe quantum dots
    • Yan M, Zhang Y, Xu K, Fu T, Qin H, Zheng X. An in vitro study of vascular endothelial toxicity of CdTe quantum dots. Toxicology 282(3), 94-103 (2011).
    • (2011) Toxicology , vol.282 , Issue.3 , pp. 94-103
    • Yan, M.1    Zhang, Y.2    Xu, K.3    Fu, T.4    Qin, H.5    Zheng, X.6
  • 80
    • 79952112034 scopus 로고    scopus 로고
    • Bioeffects of CdTe quantum dots on human umbilical vein endothelial cells
    • Wang L, Zhang J, Zheng Y, Yang J, Zhang Q, Zhu X. Bioeffects of CdTe quantum dots on human umbilical vein endothelial cells. J. Nanosci. Nanotechnol. 10(12), 8591-8596 (2010).
    • (2010) J. Nanosci. Nanotechnol. , vol.10 , Issue.12 , pp. 8591-8596
    • Wang, L.1    Zhang, J.2    Zheng, Y.3    Yang, J.4    Zhang, Q.5    Zhu, X.6
  • 81
    • 79955799430 scopus 로고    scopus 로고
    • Fibrinogen clot induced by gold-nanoparticle in vitro
    • Chen G, Ni N, Zhou J et al. Fibrinogen clot induced by gold-nanoparticle in vitro. J. Nanosci. Nanotechnol. 11(1), 74-81 (2011).
    • (2011) J. Nanosci. Nanotechnol. , vol.11 , Issue.1 , pp. 74-81
    • Chen, G.1    Ni, N.2    Zhou, J.3
  • 82
    • 67349191427 scopus 로고    scopus 로고
    • Interaction of colloidal gold nanoparticles with human blood: Effects on particle size and analysis of plasma protein binding profiles
    • Dobrovolskaia MA, Patri AK, Zheng J et al. Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles. Nanomedicine 5(2), 106-117 (2009).
    • (2009) Nanomedicine , vol.5 , Issue.2 , pp. 106-117
    • Dobrovolskaia, M.A.1    Patri, A.K.2    Zheng, J.3
  • 84
    • 84855441832 scopus 로고    scopus 로고
    • Interactions of human endothelial cells with gold nanoparticles of different morphologies
    • Bartczak D, Muskens OL, Nitti S, Sanchez Elsner T, Millar TM, Kanaras AG. Interactions of human endothelial cells with gold nanoparticles of different morphologies. Small 8(1), 122-130 (2012).
    • (2012) Small , vol.8 , Issue.1 , pp. 122-130
    • Bartczak, D.1    Muskens, O.L.2    Nitti, S.3    Sanchez Elsner, T.4    Millar, T.M.5    Kanaras, A.G.6
  • 85
    • 77956274546 scopus 로고    scopus 로고
    • Toxicity and cellular uptake of gold nanoparticles: What we have learned so far?
    • Alkilany AM, Murphy CJ. Toxicity and cellular uptake of gold nanoparticles: what we have learned so far? J. Nanopart. Res. 12(7), 2313-2333 (2010).
    • (2010) J. Nanopart. Res. , vol.12 , Issue.7 , pp. 2313-2333
    • Alkilany, A.M.1    Murphy, C.J.2
  • 86
    • 70349470888 scopus 로고    scopus 로고
    • Gold nanoparticles of diameter 1.4 nm trigger necrosis by oxidative stress and mitochondrial damage
    • Pan Y, Leifert A, Ruau D et al. Gold nanoparticles of diameter 1.4 nm trigger necrosis by oxidative stress and mitochondrial damage. Small 5(18), 2067-2076 (2009).
    • (2009) Small , vol.5 , Issue.18 , pp. 2067-2076
    • Pan, Y.1    Leifert, A.2    Ruau, D.3
  • 87
    • 84856583763 scopus 로고    scopus 로고
    • The antithrombotic and antimicrobial properties of PEG-protected silver nanoparticle coated surfaces
    • Ragaseema VM, Unnikrishnan S, Kalliyana Krishnan V, Krishnan LK. The antithrombotic and antimicrobial properties of PEG-protected silver nanoparticle coated surfaces. Biomaterials 33(11), 3083-3092 (2012).
    • (2012) Biomaterials , vol.33 , Issue.11 , pp. 3083-3092
    • Ragaseema, V.M.1    Unnikrishnan, S.2    Kalliyana Krishnan, V.3    Krishnan, L.K.4
  • 90
    • 79957824814 scopus 로고    scopus 로고
    • Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity
    • Jun EA, Lim KM, Kim K et al. Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity. Nanotoxicology 5(2), 157-167 (2011).
    • (2011) Nanotoxicology , vol.5 , Issue.2 , pp. 157-167
    • Jun, E.A.1    Lim, K.M.2    Kim, K.3
  • 91
    • 71049165212 scopus 로고    scopus 로고
    • Nanoparticles of a different source induce different patterns of activation in key biochemical and cellular components of the host response
    • Guildford AL, Poletti T, Osbourne LH, Di Cerbo A, Gatti AM, Santin M. Nanoparticles of a different source induce different patterns of activation in key biochemical and cellular components of the host response. J. R. Soc. Interface 6(41), 1213-1221 (2009).
    • (2009) J. R. Soc. Interface , vol.6 , Issue.41 , pp. 1213-1221
    • Guildford, A.L.1    Poletti, T.2    Osbourne, L.H.3    Di Cerbo, A.4    Gatti, A.M.5    Santin, M.6
  • 92
    • 42749096668 scopus 로고    scopus 로고
    • Comparative study of pulmonary responses to nano- and submicron-sized ferric oxide in rats
    • Zhu MT, Feng WY, Wang B et al. Comparative study of pulmonary responses to nano- and submicron-sized ferric oxide in rats. Toxicology 247(2-3), 102-111 (2008).
    • (2008) Toxicology , vol.247 , Issue.2-3 , pp. 102-111
    • Zhu, M.T.1    Feng, W.Y.2    Wang, B.3
  • 93
    • 80053126245 scopus 로고    scopus 로고
    • Iron core/shell nanoparticles as magnetic drug carriers: Possible interactions with the vascular compartment
    • Herrmann IK, Urner M, Hasler M et al. Iron core/shell nanoparticles as magnetic drug carriers: possible interactions with the vascular compartment. Nanomedicine (Lond.) 6(7), 1199-1213 (2011).
    • (2011) Nanomedicine (Lond.) , vol.6 , Issue.7 , pp. 1199-1213
    • Herrmann, I.K.1    Urner, M.2    Hasler, M.3
  • 94
    • 70450250214 scopus 로고    scopus 로고
    • Contact activation of kallikrein-kinin system by superparamagnetic iron oxide nanoparticles in vitro and in vivo
    • Simberg D, Zhang WM, Merkulov S et al. Contact activation of kallikrein-kinin system by superparamagnetic iron oxide nanoparticles in vitro and in vivo. J. Control. Release 140(3), 301-305 (2009).
    • (2009) J. Control. Release , vol.140 , Issue.3 , pp. 301-305
    • Simberg, D.1    Zhang, W.M.2    Merkulov, S.3
  • 95
    • 70350639581 scopus 로고    scopus 로고
    • Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs
    • Xia T, Kovochich M, Liong M et al. Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs. ACS Nano 3(10), 3273-3286 (2009).
    • (2009) ACS Nano , vol.3 , Issue.10 , pp. 3273-3286
    • Xia, T.1    Kovochich, M.2    Liong, M.3
  • 96
    • 34547838187 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs
    • Lu J, Liong M, Zink JI, Tamanoi F. Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs. Small 3(8), 1341-1346 (2007).
    • (2007) Small , vol.3 , Issue.8 , pp. 1341-1346
    • Lu, J.1    Liong, M.2    Zink, J.I.3    Tamanoi, F.4
  • 97
    • 0035715512 scopus 로고    scopus 로고
    • Health hazards due to the inhalation of amorphous silica
    • Merget R, Bauer T, Kupper HU et al. Health hazards due to the inhalation of amorphous silica. Arch. Toxicol. 75(11-12), 625-634 (2002).
    • (2002) Arch. Toxicol. , vol.75 , Issue.11-12 , pp. 625-634
    • Merget, R.1    Bauer, T.2    Kupper, H.U.3
  • 98
    • 77956076510 scopus 로고    scopus 로고
    • Procoagulant properties of bare and highly PEGylated vinyl-modified silica nanoparticles
    • Tavano R, Segat D, Reddi E et al. Procoagulant properties of bare and highly PEGylated vinyl-modified silica nanoparticles. Nanomedicine (Lond.) 5(6), 881-896 (2010).
    • (2010) Nanomedicine (Lond.) , vol.5 , Issue.6 , pp. 881-896
    • Tavano, R.1    Segat, D.2    Reddi, E.3
  • 99
    • 84865616187 scopus 로고    scopus 로고
    • Amorphous silica nanoparticles aggregate human platelets: Potential implications for vascular homeostasis
    • Corbalan JJ, Medina C, Jacoby A, Malinski T, Radomski MW. Amorphous silica nanoparticles aggregate human platelets: potential implications for vascular homeostasis. Int. J. Nanomed. 7, 631-639 (2012).
    • (2012) Int. J. Nanomed. , vol.7 , pp. 631-639
    • Corbalan, J.J.1    Medina, C.2    Jacoby, A.3    Malinski, T.4    Radomski, M.W.5
  • 100
    • 84861715726 scopus 로고    scopus 로고
    • Amorphous silica nanoparticles trigger nitric oxide/ peroxynitrite imbalance in human endothelial cells: Inflammatory and cytotoxic effects
    • Corbalan JJ, Medina C, Jacoby A, Malinski T, Radomski MW. Amorphous silica nanoparticles trigger nitric oxide/ peroxynitrite imbalance in human endothelial cells: inflammatory and cytotoxic effects. Int. J. Nanomed. 6, 2821-2835 (2011).
    • (2011) Int. J. Nanomed. , vol.6 , pp. 2821-2835
    • Corbalan, J.J.1    Medina, C.2    Jacoby, A.3    Malinski, T.4    Radomski, M.W.5
  • 101
    • 77956161513 scopus 로고    scopus 로고
    • Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF kappaB pathways
    • Liu X, Sun J. Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF kappaB pathways. Biomaterials 31(32), 8198-8209 (2010).
    • (2010) Biomaterials , vol.31 , Issue.32 , pp. 8198-8209
    • Liu, X.1    Sun, J.2
  • 102
    • 65449178474 scopus 로고    scopus 로고
    • Size-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cells
    • Napierska D, Thomassen LC, Rabolli V et al. Size-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cells. Small 5(7), 846-853 (2009).
    • (2009) Small , vol.5 , Issue.7 , pp. 846-853
    • Napierska, D.1    Thomassen, L.C.2    Rabolli, V.3
  • 103
    • 80052966765 scopus 로고    scopus 로고
    • Cytotoxicity of silica nanoparticles through exocytosis of von Willebrand factor and necrotic cell death in primary human endothelial cells
    • Bauer AT, Strozyk EA, Gorzelanny C et al. Cytotoxicity of silica nanoparticles through exocytosis of von Willebrand factor and necrotic cell death in primary human endothelial cells. Biomaterials 32(33), 8385-8393 (2011).
    • (2011) Biomaterials , vol.32 , Issue.33 , pp. 8385-8393
    • Bauer, A.T.1    Strozyk, E.A.2    Gorzelanny, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.