Delivery of drugs and macromolecules to mitochondria

Advanced Drug Delivery Reviews

Volumn 59, Issue 8, 2007, Pages 729-738

  Mukhopadhyay, Abhijit ^a   Weiner, Henry ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Lipophilic cations; Membrane insertion; Mitochondrial disease; Mitochondrial DNA; Protein and RNA import; Translocators

Indexed keywords

APOPTOTIC PATHWAY; ENERGY PRODUCTION; MITOCHONDRIA; MITOCHONDRIAL FUNCTION;

ADENOSINETRIPHOSPHATE; CELLS; DNA; GENE ENCODING; MACROMOLECULES; METABOLISM; RNA;

DRUG DELIVERY;

ALPHA TOCOPHEROL; CARRIER PROTEIN; CATION; DEQUALINIUM; NUCLEIC ACID; PEPTIDE NUCLEIC ACID; TRANSFER RNA; TRIPHENYLPHOSPHONIUM; UBIDECARENONE; UNCLASSIFIED DRUG;

ALCOHOL LIVER DISEASE; APOPTOSIS; CELL MEMBRANE PERMEABILITY; DNA REPAIR; DRUG BINDING; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG SOLUTION; DYSTONIA; ELECTRON TRANSPORT; ENERGY YIELD; EXTRACELLULAR MATRIX; FRIEDREICH ATAXIA; GENE MUTATION; GENE THERAPY; GENETIC DAMAGE; HEARING IMPAIRMENT; HUMAN; HYDROPHOBICITY; MACROMOLECULE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; OXALOSIS 1; OXIDATIVE PHOSPHORYLATION; POINT MUTATION; PRIORITY JOURNAL; PYRUVATE DEHYDROGENASE COMPLEX DEFICIENCY; REVIEW;

ANTIOXIDANTS; APOPTOSIS; CARRIER PROTEINS; DNA REPAIR; DNA, MITOCHONDRIAL; DRUG DELIVERY SYSTEMS; HUMANS; MACROMOLECULAR SUBSTANCES; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL MEMBRANES; ONIUM COMPOUNDS; OXIDATIVE STRESS; PEPTIDE NUCLEIC ACIDS; PROTEIN SORTING SIGNALS; REACTIVE OXYGEN SPECIES; SACCHAROMYCES CEREVISIAE; TRITYL COMPOUNDS;

EID: 34548240181     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2007.06.004     Document Type: Review

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