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Volumn 5, Issue 7, 2011, Pages 5390-5399

The shape effect of mesoporous silica nanoparticles on biodistribution, clearance, and biocompatibility in vivo

Author keywords

biocompatibility; biodistribution; clearance; in vivo; mesoporous silica nanoparticles (MSNs); shape

Indexed keywords

BIODISTRIBUTIONS; CLEARANCE; IN VIVO; MESOPOROUS SILICA NANOPARTICLES; SHAPE;

EID: 79961071789     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn200365a     Document Type: Conference Paper
Times cited : (780)

References (48)
  • 1
    • 51049108389 scopus 로고    scopus 로고
    • Preclinical Studies to Understand Nanoparticle Interaction with the Immune System and Its Potential Effects on Nanoparticle Biodistribution
    • Dobrovolskaia, M. A.; Aggarwal, P.; Hall, J. B.; McNeil, S. E. Preclinical Studies to Understand Nanoparticle Interaction with the Immune System and Its Potential Effects on Nanoparticle Biodistribution Mol. Pharmaceutics 2008, 5, 487-495
    • (2008) Mol. Pharmaceutics , vol.5 , pp. 487-495
    • Dobrovolskaia, M.A.1    Aggarwal, P.2    Hall, J.B.3    McNeil, S.E.4
  • 2
    • 78751545634 scopus 로고    scopus 로고
    • Multifunctional Gold Nanoshells on Silica Nanorattles: A Platform for the Combination of Photothermal Therapy and Chemotherapy with Low Systemic Toxicity
    • Liu, H. Y.; Chen, D.; Li, L. L.; Liu, T. L.; Tan, L. F.; Wu, X. L.; Tang, F. Q. Multifunctional Gold Nanoshells on Silica Nanorattles: A Platform for the Combination of Photothermal Therapy and Chemotherapy with Low Systemic Toxicity Angew. Chem., Int. Ed. 2011, 50, 891-895
    • (2011) Angew. Chem., Int. Ed. , vol.50 , pp. 891-895
    • Liu, H.Y.1    Chen, D.2    Li, L.L.3    Liu, T.L.4    Tan, L.F.5    Wu, X.L.6    Tang, F.Q.7
  • 3
    • 78649595321 scopus 로고    scopus 로고
    • In Vivo Delivery of Silica Nanorattle Encapsulated Docetaxel for Liver Cancer Therapy with Low Toxicity and High Efficacy
    • Li, L. L.; Tang, F. Q.; Liu, H. Y.; Liu, T. L.; Hao, N. J.; Chen, D.; Teng, X.; He, J. Q. In Vivo Delivery of Silica Nanorattle Encapsulated Docetaxel for Liver Cancer Therapy with Low Toxicity and High Efficacy ACS Nano 2010, 4, 6874-6882
    • (2010) ACS Nano , vol.4 , pp. 6874-6882
    • Li, L.L.1    Tang, F.Q.2    Liu, H.Y.3    Liu, T.L.4    Hao, N.J.5    Chen, D.6    Teng, X.7    He, J.Q.8
  • 4
    • 38049161380 scopus 로고    scopus 로고
    • Mesoporous Silica Particles Induce Size Dependent Effects on Human Dendritic Cells
    • Vallhov, H.; Gabrielsson, S.; Stromme, M.; Scheynius, A.; Garcia-Bennett, A. E. Mesoporous Silica Particles Induce Size Dependent Effects on Human Dendritic Cells Nano Lett. 2007, 7, 3576-3582
    • (2007) Nano Lett. , vol.7 , pp. 3576-3582
    • Vallhov, H.1    Gabrielsson, S.2    Stromme, M.3    Scheynius, A.4    Garcia-Bennett, A.E.5
  • 5
    • 40449122796 scopus 로고    scopus 로고
    • Nanoparticle-mediated cellular response is size-dependent
    • DOI 10.1038/nnano.2008.30, PII NNANO200830
    • Jiang, W.; Kim, B. Y. S.; Rutka, J. T.; Chan, W. C. W. Nanoparticle-Mediated Cellular Response Is Size-Dependent Nat. Nanotechnol. 2008, 3, 145-150 (Pubitemid 351355131)
    • (2008) Nature Nanotechnology , vol.3 , Issue.3 , pp. 145-150
    • Jiang, W.1    Kim, B.Y.S.2    Rutka, J.T.3    Chan, W.C.W.4
  • 6
    • 33646397592 scopus 로고    scopus 로고
    • Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian cells
    • Chithrani, B. D.; Ghazani, A. A.; Chan, W. C. Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian cells Nano Lett. 2006, 6, 662-668
    • (2006) Nano Lett. , vol.6 , pp. 662-668
    • Chithrani, B.D.1    Ghazani, A.A.2    Chan, W.C.3
  • 7
    • 34147144905 scopus 로고    scopus 로고
    • The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles in 3T3-L1 cells and human mesenchymal stem cells
    • DOI 10.1016/j.biomaterials.2007.03.006, PII S0142961207002049
    • Chung, T. H.; Wu, S. H.; Yao, M.; Lu, C. W.; Lin, Y. S.; Hung, Y.; Mou, C. Y.; Chen, Y. C.; Huang, D. M. The Effect of Surface Charge on the Uptake and Biological Function of Mesoporous Silica Nanoparticles 3T3-L1 Cells and Human Mesenchymal Stem Cells Biomaterials 2007, 28, 2959-2966 (Pubitemid 46560868)
    • (2007) Biomaterials , vol.28 , Issue.19 , pp. 2959-2966
    • Chung, T.-H.1    Wu, S.-H.2    Yao, M.3    Lu, C.-W.4    Lin, Y.-S.5    Hung, Y.6    Mou, C.-Y.7    Chen, Y.-C.8    Huang, D.-M.9
  • 9
    • 33847095924 scopus 로고    scopus 로고
    • Effect of PEG conformation and particle size on the cellular uptake efficiency of nanoparticles with the HepG2 cells
    • DOI 10.1016/j.jconrel.2006.11.028, PII S0168365906006936
    • Hu, Y.; Xie, J. W.; Tong, Y. W.; Wang, C. H. Effect of PEG Conformation and Particle Size on the Cellular Uptake Efficiency of Nanoparticles with the HepG2 Cells J. Controlled Release 2007, 118, 7-17 (Pubitemid 46283099)
    • (2007) Journal of Controlled Release , vol.118 , Issue.1 , pp. 7-17
    • Hu, Y.1    Xie, J.2    Tong, Y.W.3    Wang, C.-H.4
  • 10
    • 73349127843 scopus 로고    scopus 로고
    • Control of the in Vivo Biodistribution of Hybrid Nanoparticles with Different Poly(ethylene glycol) Coatings
    • Faure, A. C.; Dufort, S.; Josserand, V.; Perriat, P.; Coll, J. L.; Roux, S.; Tillement, O. Control of the in Vivo Biodistribution of Hybrid Nanoparticles with Different Poly(ethylene glycol) Coatings Small 2009, 5, 2565-2575
    • (2009) Small , vol.5 , pp. 2565-2575
    • Faure, A.C.1    Dufort, S.2    Josserand, V.3    Perriat, P.4    Coll, J.L.5    Roux, S.6    Tillement, O.7
  • 11
    • 77950850818 scopus 로고    scopus 로고
    • Impacts of Mesoporous Silica Nanoparticle Size, Pore Ordering, and Pore Integrity on Hemolytic Activity
    • Lin, Y. S.; Haynes, C. L. Impacts of Mesoporous Silica Nanoparticle Size, Pore Ordering, and Pore Integrity on Hemolytic Activity J. Am. Chem. Soc. 2010, 132, 4834-4842
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 4834-4842
    • Lin, Y.S.1    Haynes, C.L.2
  • 12
    • 66749179382 scopus 로고    scopus 로고
    • Tissue- and Organ-Selective Biodistribution of NIR Fluorescent Quantum Dots
    • Choi, H. S.; Ipe, B. I.; Misra, P.; Lee, J. H.; Bawendi, M. G.; Frangioni, J. V. Tissue- and Organ-Selective Biodistribution of NIR Fluorescent Quantum Dots Nano Lett. 2009, 9, 2354-2359
    • (2009) Nano Lett. , vol.9 , pp. 2354-2359
    • Choi, H.S.1    Ipe, B.I.2    Misra, P.3    Lee, J.H.4    Bawendi, M.G.5    Frangioni, J.V.6
  • 14
    • 77953020259 scopus 로고    scopus 로고
    • Surface Charge-Mediated Rapid Hepatobiliary Excretion of Mesoporous Silica Nanoparticles
    • Souris, J. S.; Lee, C. H.; Cheng, S. H.; Chen, C. T.; Yang, C. S.; Ho, J. A.; Mou, C. Y.; Lo, L. W. Surface Charge-Mediated Rapid Hepatobiliary Excretion of Mesoporous Silica Nanoparticles Biomaterials 2010, 31, 5564-5574
    • (2010) Biomaterials , vol.31 , pp. 5564-5574
    • Souris, J.S.1    Lee, C.H.2    Cheng, S.H.3    Chen, C.T.4    Yang, C.S.5    Ho, J.A.6    Mou, C.Y.7    Lo, L.W.8
  • 15
    • 39649115201 scopus 로고    scopus 로고
    • Particle Size-Dependent Organ Distribution of Gold Nanoparticles after Intravenous Administration
    • De Jong, W. H.; Hagens, W. I.; Krystek, P.; Burger, M. C.; Sips, A. J.; Geertsma, R. E. Particle Size-Dependent Organ Distribution of Gold Nanoparticles after Intravenous Administration Biomaterials 2008, 29, 1912-1919
    • (2008) Biomaterials , vol.29 , pp. 1912-1919
    • De Jong, W.H.1    Hagens, W.I.2    Krystek, P.3    Burger, M.C.4    Sips, A.J.5    Geertsma, R.E.6
  • 16
    • 58149113055 scopus 로고    scopus 로고
    • In Vivo Study of Biodistribution and Urinary Excretion of Surface-Modified Silica Nanoparticles
    • He, X. X.; Nie, H. L.; Wang, K. M.; Tan, W. H.; Wu, X.; Zhang, P. F. In Vivo Study of Biodistribution and Urinary Excretion of Surface-Modified Silica Nanoparticles Anal. Chem. 2008, 80, 9597-9603
    • (2008) Anal. Chem. , vol.80 , pp. 9597-9603
    • He, X.X.1    Nie, H.L.2    Wang, K.M.3    Tan, W.H.4    Wu, X.5    Zhang, P.F.6
  • 17
    • 34248402413 scopus 로고    scopus 로고
    • Shape effects of filaments versus spherical particles in flow and drug delivery
    • DOI 10.1038/nnano.2007.70, PII NNANO200770
    • Geng, Y.; Dalhaimer, P.; Cai, S. S.; Tsai, R.; Tewari, M.; Minko, T.; Discher, D. E. Shape Effects of Filaments versus Spherical Particles in Flow and Drug Delivery Nat. Nanotechnol. 2007, 2, 249-255 (Pubitemid 46739812)
    • (2007) Nature Nanotechnology , vol.2 , Issue.4 , pp. 249-255
    • Geng, Y.1    Dalhaimer, P.2    Cai, S.3    Tsai, R.4    Tewari, M.5    Minko, T.6    Discher, D.E.7
  • 19
    • 52249093974 scopus 로고    scopus 로고
    • Shape Effects of Nanoparticles Conjugated with Cell-Penetrating Peptides (HIV Tat PTD) on CHO Cell Uptake
    • Zhang, K.; Fang, H. F.; Chen, Z. Y.; Taylor, J. S. A.; Wooley, K. L. Shape Effects of Nanoparticles Conjugated with Cell-Penetrating Peptides (HIV Tat PTD) on CHO Cell Uptake Bioconjugate Chem. 2008, 19, 1880-1887
    • (2008) Bioconjugate Chem. , vol.19 , pp. 1880-1887
    • Zhang, K.1    Fang, H.F.2    Chen, Z.Y.3    Taylor, J.S.A.4    Wooley, K.L.5
  • 20
    • 34248402413 scopus 로고    scopus 로고
    • Shape effects of filaments versus spherical particles in flow and drug delivery
    • DOI 10.1038/nnano.2007.70, PII NNANO200770
    • Geng, Y.; Dalhaimer, P.; Cai, S.; Tsai, R.; Tewari, M.; Minko, T.; Discher, D. E. Shape Effects of Filaments versus Spherical Particles in Flow and Drug Delivery Nat. Nanotechnol. 2007, 2, 249-255 (Pubitemid 46739812)
    • (2007) Nature Nanotechnology , vol.2 , Issue.4 , pp. 249-255
    • Geng, Y.1    Dalhaimer, P.2    Cai, S.3    Tsai, R.4    Tewari, M.5    Minko, T.6    Discher, D.E.7
  • 21
    • 34547178393 scopus 로고    scopus 로고
    • Particle shape: A new design parameter for micro- and nanoscale drug delivery carriers
    • DOI 10.1016/j.jconrel.2007.03.022, PII S0168365907001769
    • Champion, J. A.; Katare, Y. K.; Mitragotri, S. Particle Shape: A New Design Parameter for Micro- and Nanoscale Drug Delivery Carriers J. Controlled Release 2007, 121, 3-9 (Pubitemid 47126059)
    • (2007) Journal of Controlled Release , vol.121 , Issue.1-2 , pp. 3-9
    • Champion, J.A.1    Katare, Y.K.2    Mitragotri, S.3
  • 22
    • 34249779229 scopus 로고    scopus 로고
    • Mesoporous silica nanomaterial-based biotechnological and biomedical delivery systems
    • DOI 10.2217/17435889.2.1.99
    • Giri, S.; Trewyn, B. G.; Lin, V. S. Y. Mesoporous Silica Nanomaterial-Based Biotechnological and Biomedical Delivery Systems Nanomedicine 2007, 2, 99-111 (Pubitemid 46845781)
    • (2007) Nanomedicine , vol.2 , Issue.1 , pp. 99-111
    • Giri, S.1    Trewyn, B.G.2    Lin, V.S.Y.3
  • 24
    • 34249780352 scopus 로고    scopus 로고
    • Mesoporous silica nanoparticles for drug delivery and biosensing applications
    • DOI 10.1002/adfm.200601191
    • Slowing, I. I.; Trewyn, B. G.; Giri, S.; Lin, V. S. Y. Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications Adv. Funct. Mater. 2007, 17, 1225-1236 (Pubitemid 46847636)
    • (2007) Advanced Functional Materials , vol.17 , Issue.8 , pp. 1225-1236
    • Slowing, I.I.1    Trewyn, B.G.2    Giri, S.3    Lin, V.S.-Y.4
  • 25
    • 39449103683 scopus 로고    scopus 로고
    • High-contrast paramagnetic fluorescent mesoporous silica nanorods as a multifunctional cell-imaging probe
    • DOI 10.1002/smll.200700457
    • Tsai, C. P.; Hung, Y.; Chou, Y. H.; Huang, D. M.; Hsiao, J. K.; Chang, C.; Chen, Y. C.; Mou, C. Y. High-Contrast Paramagnetic Fluorescent Mesoporous Silica Nanorods as a Multifunctional Cell-Imaging Probe Small 2008, 4, 186-191 (Pubitemid 351271148)
    • (2008) Small , vol.4 , Issue.2 , pp. 186-191
    • Tsai, C.-P.1    Hung, Y.2    Chou, Y.-H.3    Huang, D.-M.4    Hsiao, J.-K.5    Chang, C.6    Chen, Y.-C.7    Mou, C.-Y.8
  • 26
    • 70449088926 scopus 로고    scopus 로고
    • The Effect of the Shape of Mesoporous Silica Nanoparticles on Cellular Uptake and Cell Function
    • Huang, X. L.; Teng, X.; Chen, D.; Tang, F. Q.; He, J. Q. The Effect of the Shape of Mesoporous Silica Nanoparticles on Cellular Uptake and Cell Function Biomaterials 2010, 31, 438-448
    • (2010) Biomaterials , vol.31 , pp. 438-448
    • Huang, X.L.1    Teng, X.2    Chen, D.3    Tang, F.Q.4    He, J.Q.5
  • 27
    • 12844286088 scopus 로고    scopus 로고
    • Bright and stable core-shell fluorescent silica nanoparticles
    • DOI 10.1021/nl0482478
    • Ow, H.; Larson, D. R.; Srivastava, M.; Baird, B. A.; Webb, W. W.; Wiesner, U. Bright and Stable Core-Shell Fluorescent Silica Nanoparticles Nano Lett. 2005, 5, 113-117 (Pubitemid 40168913)
    • (2005) Nano Letters , vol.5 , Issue.1 , pp. 113-117
    • Ow, H.1    Larson, D.R.2    Srivastava, M.3    Baird, B.A.4    Webb, W.W.5    Wiesnert, U.6
  • 28
    • 31544456670 scopus 로고    scopus 로고
    • Multicolor FRET silica nanoparticles by single wavelength excitation
    • DOI 10.1021/nl052105b
    • Wang, L.; Tan, W. H. Multicolor FRET Silica Nanoparticles by Single Wavelength Excitation Nano Lett. 2006, 6, 84-88 (Pubitemid 43166106)
    • (2006) Nano Letters , vol.6 , Issue.1 , pp. 84-88
    • Wang, L.1    Tan, W.2
  • 29
    • 33750234489 scopus 로고    scopus 로고
    • Fluorescent core-shell silica nanoparticles: Towards 'lab on a particle' architectures for nanobiotechnology
    • DOI 10.1039/b600562b
    • Burns, A.; Ow, H.; Wiesner, U. Fluorescent Core-Shell Silica Nanoparticles: Towards "Lab on a Particle" Architectures for Nanobiotechnology Chem. Soc. Rev. 2006, 35, 1028-1042 (Pubitemid 44611717)
    • (2006) Chemical Society Reviews , vol.35 , Issue.11 , pp. 1028-1042
    • Burns, A.1    Ow, H.2    Wiesner, U.3
  • 30
    • 51049104302 scopus 로고    scopus 로고
    • Pharmacokinetics and Biodistribution of Nanoparticles
    • Li, S. D.; Huang, L. Pharmacokinetics and Biodistribution of Nanoparticles Mol. Pharm. 2008, 5, 496-504
    • (2008) Mol. Pharm. , vol.5 , pp. 496-504
    • Li, S.D.1    Huang, L.2
  • 31
    • 18244410117 scopus 로고    scopus 로고
    • Phase behaviour of polymer-grafted DPPC membranes for drug delivery systems design
    • DOI 10.1007/s10973-005-0669-7
    • Pappalardo, M.; Milardi, D.; Grasso, D.; La Rosa, C. Phase Behaviour of Polymer-Grafted DPPC Membranes for Drug Delivery Systems Design J. Therm. Anal. Calorim. 2005, 80, 413-418 (Pubitemid 40626516)
    • (2005) Journal of Thermal Analysis and Calorimetry , vol.80 , Issue.2 , pp. 413-418
    • Pappalardo, M.1    Milardi, D.2    Grasso, D.3    La Rosa, C.4
  • 32
    • 0032115878 scopus 로고    scopus 로고
    • Poly(ethylene oxide) grafted to silicon surfaces: Grafting density and protein adsorption
    • Sofia, S.; Premnath, V.; Merrill, E. Poly(Ethylene Oxide) Grafted to Silicon Surfaces: Grafting Density and Protein Adsorption Macromolecules 1998, 31, 5059-5070 (Pubitemid 128565524)
    • (1998) Macromolecules , vol.31 , Issue.15 , pp. 5059-5070
    • Sofia, S.J.1    Premnath, V.2    Merrill, E.W.3
  • 33
    • 77950862458 scopus 로고    scopus 로고
    • Fluorescence Lymph Node Mapping in Living Mice Using Quantum Dots and a Compression Technique
    • Inoue, Y.; Kiryu, S.; Watanabe, M.; Oyaizu, N.; Ohtomo, K. Fluorescence Lymph Node Mapping in Living Mice Using Quantum Dots and a Compression Technique J. Fluoresc. 2010, 20, 599-606
    • (2010) J. Fluoresc. , vol.20 , pp. 599-606
    • Inoue, Y.1    Kiryu, S.2    Watanabe, M.3    Oyaizu, N.4    Ohtomo, K.5
  • 34
    • 77950859837 scopus 로고    scopus 로고
    • The Blood-Brain Barrier Penetration and Distribution of PEGylated Fluorescein-Doped Magnetic Silica Nanoparticles in Rat Brain
    • Ku, S. T.; Yan, F.; Wang, Y.; Sun, Y.; Yang, N.; Ye, L. The Blood-Brain Barrier Penetration and Distribution of PEGylated Fluorescein-Doped Magnetic Silica Nanoparticles in Rat Brain Biochem. Biophys. Res. Commun. 2010, 394, 871-876
    • (2010) Biochem. Biophys. Res. Commun. , vol.394 , pp. 871-876
    • Ku, S.T.1    Yan, F.2    Wang, Y.3    Sun, Y.4    Yang, N.5    Ye, L.6
  • 37
    • 78651342869 scopus 로고    scopus 로고
    • In Vivo Biodistribution and Urinary Excretion of Mesoporous Silica Nanoparticles: Effects of Particle Size and PEGylation
    • He, Q. J.; Zhang, Z. W.; Gao, F.; Li, Y. P.; Shi, J. L. In Vivo Biodistribution and Urinary Excretion of Mesoporous Silica Nanoparticles: Effects of Particle Size and PEGylation Small 2011, 7, 271-280
    • (2011) Small , vol.7 , pp. 271-280
    • He, Q.J.1    Zhang, Z.W.2    Gao, F.3    Li, Y.P.4    Shi, J.L.5
  • 38
    • 78650266662 scopus 로고    scopus 로고
    • Single and Repeated Dose Toxicity of Mesoporous Hollow Silica Nanoparticles in Intravenously Exposed Mice
    • Liu, T. L.; Li, L. L.; Teng, X.; Huang, X. L.; Liu, H. Y.; Chen, D.; Ren, J.; He, J. Q.; Tang, F. Q. Single and Repeated Dose Toxicity of Mesoporous Hollow Silica Nanoparticles in Intravenously Exposed Mice Biomaterials 2011, 32, 1657-1668
    • (2011) Biomaterials , vol.32 , pp. 1657-1668
    • Liu, T.L.1    Li, L.L.2    Teng, X.3    Huang, X.L.4    Liu, H.Y.5    Chen, D.6    Ren, J.7    He, J.Q.8    Tang, F.Q.9
  • 39
    • 40349112868 scopus 로고    scopus 로고
    • Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy
    • DOI 10.1073/pnas.0707654105
    • Liu, Z.; Davis, C.; Cai, W. B.; He, L. N.; Chen, X. Y.; Dai, H. J. Circulation and Long-Term Fate of Functionalized, Biocompatible Single-Walled Carbon Nanotubes in Mice Probed by Raman Spectroscopy Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 1410-1415 (Pubitemid 351346531)
    • (2008) Proceedings of the National Academy of Sciences of the United States of America , vol.105 , Issue.5 , pp. 1410-1415
    • Liu, Z.1    Davis, C.2    Cai, W.3    He, L.4    Chen, X.5    Dai, H.6
  • 40
    • 77955613395 scopus 로고    scopus 로고
    • Biocompatibility, Biodistribution, and Drug-Delivery Efficiency of Mesoporous Silica Nanoparticles for Cancer Therapy in Animals
    • Lu, J.; Liong, M.; Li, Z.; Zink, J. I.; Tamanoi, F. Biocompatibility, Biodistribution, and Drug-Delivery Efficiency of Mesoporous Silica Nanoparticles for Cancer Therapy in Animals Small 2010, 6, 1794-1805
    • (2010) Small , vol.6 , pp. 1794-1805
    • Lu, J.1    Liong, M.2    Li, Z.3    Zink, J.I.4    Tamanoi, F.5
  • 42
    • 42549152143 scopus 로고    scopus 로고
    • Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats
    • DOI 10.1021/mp7001285
    • Jain, T. K.; Reddy, M. K.; Morales, M. A.; Leslie-Pelecky, D. L.; Labhasetwar, V. Biodistribution, Clearance, and Biocompatibility of Iron Oxide Magnetic Nanoparticles in Rats Mol. Pharm. 2008, 5, 316-327 (Pubitemid 351579134)
    • (2008) Molecular Pharmaceutics , vol.5 , Issue.2 , pp. 316-327
    • Jain, T.K.1    Reddy, M.K.2    Morales, M.A.3    Leslie-Pelecky, D.L.4    Labhasetwar, V.5
  • 43
    • 77950850818 scopus 로고    scopus 로고
    • Impacts of Mesoporous Silica Nanoparticle Size, Pore Ordering, and Pore Integrity on Hemolytic Activity
    • Lin, Y. S.; Haynes, C. L. Impacts of Mesoporous Silica Nanoparticle Size, Pore Ordering, and Pore Integrity on Hemolytic Activity J. Am. Chem. Soc. 2010, 132, 4834-4842
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 4834-4842
    • Lin, Y.S.1    Haynes, C.L.2
  • 44
    • 58149465609 scopus 로고    scopus 로고
    • Mesoporous Silica Nanoparticles for Reducing Hemolytic Activity towards Mammalian Red Blood Cells
    • Slowing, I. I.; Wu, C. W.; Vivero-Escoto, J. L.; Lin, V. S. Y. Mesoporous Silica Nanoparticles for Reducing Hemolytic Activity towards Mammalian Red Blood Cells Small 2009, 5, 57-62
    • (2009) Small , vol.5 , pp. 57-62
    • Slowing, I.I.1    Wu, C.W.2    Vivero-Escoto, J.L.3    Lin, V.S.Y.4
  • 45
    • 46749123819 scopus 로고    scopus 로고
    • Mesoporous Silica Nanoparticles as Controlled Release Drug Delivery and Gene Transfection Carriers
    • Slowing, I. I.; Vivero-Escoto, J. L.; Wu, C. W.; Lin, V. S. Y. Mesoporous Silica Nanoparticles as Controlled Release Drug Delivery and Gene Transfection Carriers Adv. Drug Delivery Rev. 2008, 60, 1278-1288
    • (2008) Adv. Drug Delivery Rev. , vol.60 , pp. 1278-1288
    • Slowing, I.I.1    Vivero-Escoto, J.L.2    Wu, C.W.3    Lin, V.S.Y.4
  • 46
    • 49549098376 scopus 로고    scopus 로고
    • Internalization of Mesoporous Silica Nanoparticles Induces Transient but Not Sufficient Osteogenic Signals in Human Mesenchymal Stem Cells
    • Huang, D. M.; Chung, T. H.; Hung, Y.; Lu, F.; Wu, S. H.; Mou, C. Y.; Yao, M.; Chen, Y. C. Internalization of Mesoporous Silica Nanoparticles Induces Transient but Not Sufficient Osteogenic Signals in Human Mesenchymal Stem Cells Toxicol. Appl. Pharmacol. 2008, 231, 208-215
    • (2008) Toxicol. Appl. Pharmacol. , vol.231 , pp. 208-215
    • Huang, D.M.1    Chung, T.H.2    Hung, Y.3    Lu, F.4    Wu, S.H.5    Mou, C.Y.6    Yao, M.7    Chen, Y.C.8
  • 47
    • 72149133357 scopus 로고    scopus 로고
    • Tuning the Cellular Uptake and Cytotoxicity Properties of Oligonucleotide Intercalator-Functionalized Mesoporous Silica Nanoparticles with Human Cervical Cancer Cells HeLa
    • Vivero-Escoto, J. L.; Slowing, I. I.; Lin, V. S. Y. Tuning the Cellular Uptake and Cytotoxicity Properties of Oligonucleotide Intercalator- Functionalized Mesoporous Silica Nanoparticles with Human Cervical Cancer Cells HeLa Biomaterials 2010, 31, 1325-1333
    • (2010) Biomaterials , vol.31 , pp. 1325-1333
    • Vivero-Escoto, J.L.1    Slowing, I.I.2    Lin, V.S.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.