-
1
-
-
84868473102
-
Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment
-
COI: 1:CAS:528:DC%2BC38Xhs1arsb%2FJ, PID: 23007741
-
Schett G, Gravallese E (2012) Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment. Nat Rev Rheumatol 8:656–664
-
(2012)
Nat Rev Rheumatol
, vol.8
, pp. 656-664
-
-
Schett, G.1
Gravallese, E.2
-
2
-
-
0033789358
-
Cellular mechanisms and the role of cytokines in bone erosions in rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BD3cXnslWjsrs%3D, PID: 11037873
-
Gravallese EM, Goldring SR (2000) Cellular mechanisms and the role of cytokines in bone erosions in rheumatoid arthritis. Arthritis Rheum 43:2143–2151
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2143-2151
-
-
Gravallese, E.M.1
Goldring, S.R.2
-
3
-
-
84979854444
-
-
Academic Press, London, Burlington MA, San Diego CA
-
Gravallese EM, Goldring SR, Schett G (2015) The role of the immune system in the local and systemic bone loss in inflammatory arthritis, in Osteimmunology: interaction of the Immune and skeletal systems, 2nd edn. Academic Press, London, Burlington MA, San Diego CA
-
(2015)
The role of the immune system in the local and systemic bone loss in inflammatory arthritis, in Osteimmunology: interaction of the Immune and skeletal systems
-
-
Gravallese, E.M.1
Goldring, S.R.2
Schett, G.3
-
4
-
-
0029868840
-
Bone mass measurement and bone metabolism in rheumatoid arthritis: a review
-
COI: 1:STN:280:DyaK283hs12itA%3D%3D, PID: 8624634
-
Deodhar AA, Woolf AD (1996) Bone mass measurement and bone metabolism in rheumatoid arthritis: a review. Br J Rheumatol 35:309–322
-
(1996)
Br J Rheumatol
, vol.35
, pp. 309-322
-
-
Deodhar, A.A.1
Woolf, A.D.2
-
5
-
-
3042666553
-
Bone loss in inflammatory arthritis: mechanisms and treatment strategies
-
PID: 15201606
-
Walsh NC, Gravallese EM (2004) Bone loss in inflammatory arthritis: mechanisms and treatment strategies. Curr Opin Rheumatol 16:419–427
-
(2004)
Curr Opin Rheumatol
, vol.16
, pp. 419-427
-
-
Walsh, N.C.1
Gravallese, E.M.2
-
6
-
-
0025983905
-
Rheumatoid factors antedating clinical rheumatoid arthritis
-
COI: 1:STN:280:DyaK38%2FpvFahug%3D%3D, PID: 1757925
-
Aho K, Heliovaara M, Maatela J, Tuomi T, Palosuo T (1991) Rheumatoid factors antedating clinical rheumatoid arthritis. J Rheumatol 18:1282–1284
-
(1991)
J Rheumatol
, vol.18
, pp. 1282-1284
-
-
Aho, K.1
Heliovaara, M.2
Maatela, J.3
Tuomi, T.4
Palosuo, T.5
-
7
-
-
18744430797
-
Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis
-
PID: 14558078
-
Rantapaa-Dahlqvist S, de Jong BA, Berglin E et al (2003) Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. Arthritis Rheum 48:2741–2749
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2741-2749
-
-
Rantapaa-Dahlqvist, S.1
de Jong, B.A.2
Berglin, E.3
-
8
-
-
84886014796
-
Anti-citrullinated peptide autoantibodies, human leukocyte antigen shared epitope and risk of future rheumatoid arthritis: a nested case–control study
-
PID: 24286474
-
Arkema EV, Goldstein BL, Robinson W et al (2013) Anti-citrullinated peptide autoantibodies, human leukocyte antigen shared epitope and risk of future rheumatoid arthritis: a nested case–control study. Arthritis Res Ther 15:R159
-
(2013)
Arthritis Res Ther
, vol.15
, pp. R159
-
-
Arkema, E.V.1
Goldstein, B.L.2
Robinson, W.3
-
9
-
-
84925438428
-
The role of citrullinated protein antibodies in predicting erosive disease in rheumatoid arthritis: a systematic literature review and meta-analysis
-
COI: 1:STN:280:DC%2BC2Mnpt1Sgug%3D%3D, PID: 25821469
-
Jilani AA, Mackworth-Young CG (2015) The role of citrullinated protein antibodies in predicting erosive disease in rheumatoid arthritis: a systematic literature review and meta-analysis. Int J Rheumatol 2015:728610
-
(2015)
Int J Rheumatol
, vol.2015
, pp. 728610
-
-
Jilani, A.A.1
Mackworth-Young, C.G.2
-
10
-
-
84898013615
-
Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies
-
PID: 23520034
-
Kleyer A, Finzel S, Rech J et al (2014) Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies. Ann Rheum Dis 73:854–860
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 854-860
-
-
Kleyer, A.1
Finzel, S.2
Rech, J.3
-
11
-
-
0035153246
-
TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis
-
COI: 1:STN:280:DC%2BD3Mnltl2rsA%3D%3D, PID: 11696430
-
Pettit AR, Ji H, von Stechow D et al (2001) TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. Am J Pathol 159:1689–1699
-
(2001)
Am J Pathol
, vol.159
, pp. 1689-1699
-
-
Pettit, A.R.1
Ji, H.2
von Stechow, D.3
-
12
-
-
0036853902
-
Osteoclasts are essential for TNF-alpha-mediated joint destruction
-
COI: 1:CAS:528:DC%2BD38XovFOnu7s%3D, PID: 12438440
-
Redlich K, Hayer S, Ricci R et al (2002) Osteoclasts are essential for TNF-alpha-mediated joint destruction. J Clin Invest 110:1419–1427
-
(2002)
J Clin Invest
, vol.110
, pp. 1419-1427
-
-
Redlich, K.1
Hayer, S.2
Ricci, R.3
-
13
-
-
0031894140
-
Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis
-
COI: 1:STN:280:DyaK1c3gs1Cgsw%3D%3D, PID: 9546355
-
Gravallese EM, Harada Y, Wang JT, Gorn AH, Thornhill TS, Goldring SR (1998) Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis. Am J Pathol 152:943–951
-
(1998)
Am J Pathol
, vol.152
, pp. 943-951
-
-
Gravallese, E.M.1
Harada, Y.2
Wang, J.T.3
Gorn, A.H.4
Thornhill, T.S.5
Goldring, S.R.6
-
14
-
-
0033581952
-
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
-
COI: 1:CAS:528:DyaK1MXnvFShsLg%3D, PID: 10580503
-
Kong YY, Feige U, Sarosi I et al (1999) Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature 402:304–309
-
(1999)
Nature
, vol.402
, pp. 304-309
-
-
Kong, Y.Y.1
Feige, U.2
Sarosi, I.3
-
15
-
-
0034122050
-
Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor
-
COI: 1:STN:280:DC%2BD3c7lsFGgsg%3D%3D, PID: 10693863
-
Gravallese EM, Manning C, Tsay A et al (2000) Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor. Arthritis Rheum 43:250–258
-
(2000)
Arthritis Rheum
, vol.43
, pp. 250-258
-
-
Gravallese, E.M.1
Manning, C.2
Tsay, A.3
-
16
-
-
34347348860
-
Bone erosions in rheumatoid arthritis can be repaired through reduction in disease activity with conventional disease-modifying antirheumatic drugs
-
PID: 16646983
-
Ideguchi H, Ohno S, Hattori H, Senuma A, Ishigatsubo Y (2006) Bone erosions in rheumatoid arthritis can be repaired through reduction in disease activity with conventional disease-modifying antirheumatic drugs. Arthritis Res Ther 8:R76
-
(2006)
Arthritis Res Ther
, vol.8
, pp. R76
-
-
Ideguchi, H.1
Ohno, S.2
Hattori, H.3
Senuma, A.4
Ishigatsubo, Y.5
-
17
-
-
73249137735
-
Bone remodeling in rheumatic disease: a question of balance
-
COI: 1:CAS:528:DC%2BC3cXjslaqsrk%3D, PID: 20193007
-
Walsh NC, Gravallese EM (2010) Bone remodeling in rheumatic disease: a question of balance. Immunol Rev 233:301–312
-
(2010)
Immunol Rev
, vol.233
, pp. 301-312
-
-
Walsh, N.C.1
Gravallese, E.M.2
-
18
-
-
79958131583
-
Structural damage in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: traditional views, novel insights gained from TNF blockade, and concepts for the future
-
PID: 21624183
-
Schett G, Coates LC, Ash ZR, Finzel S, Conaghan PG (2011) Structural damage in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: traditional views, novel insights gained from TNF blockade, and concepts for the future. Arthritis Res Ther 13(Suppl 1):S4
-
(2011)
Arthritis Res Ther
, vol.13
, pp. S4
-
-
Schett, G.1
Coates, L.C.2
Ash, Z.R.3
Finzel, S.4
Conaghan, P.G.5
-
19
-
-
84901444670
-
The genetic basis of ankylosing spondylitis: new insights into disease pathogenesis
-
COI: 1:CAS:528:DC%2BC2MXivFWnsL8%3D, PID: 24971029
-
Tsui FW, Tsui HW, Akram A, Haroon N, Inman RD (2014) The genetic basis of ankylosing spondylitis: new insights into disease pathogenesis. Appl Clin Genet 7:105–115
-
(2014)
Appl Clin Genet
, vol.7
, pp. 105-115
-
-
Tsui, F.W.1
Tsui, H.W.2
Akram, A.3
Haroon, N.4
Inman, R.D.5
-
20
-
-
84928783399
-
Concepts of pathogenesis in psoriatic arthritis: genotype determines clinical phenotype
-
PID: 25948071
-
FitzGerald O, Haroon M, Giles JT, Winchester R (2015) Concepts of pathogenesis in psoriatic arthritis: genotype determines clinical phenotype. Arthritis Res Ther 17:115
-
(2015)
Arthritis Res Ther
, vol.17
, pp. 115
-
-
FitzGerald, O.1
Haroon, M.2
Giles, J.T.3
Winchester, R.4
-
21
-
-
67651154370
-
Progress in spondylarthritis. Mechanisms of new bone formation in spondyloarthritis
-
PID: 19439035
-
Lories RJ, Luyten FP, de Vlam K (2009) Progress in spondylarthritis. Mechanisms of new bone formation in spondyloarthritis. Arthritis Res Ther 11:221
-
(2009)
Arthritis Res Ther
, vol.11
, pp. 221
-
-
Lories, R.J.1
Luyten, F.P.2
de Vlam, K.3
-
22
-
-
0021285154
-
Chondroclasts and osteoclasts at subchondral sites of erosion in the rheumatoid joint
-
COI: 1:STN:280:DyaL2czgslyqsg%3D%3D, PID: 6236824
-
Bromley M, Woolley DE (1984) Chondroclasts and osteoclasts at subchondral sites of erosion in the rheumatoid joint. Arthritis Rheum 27:968–975
-
(1984)
Arthritis Rheum
, vol.27
, pp. 968-975
-
-
Bromley, M.1
Woolley, D.E.2
-
23
-
-
0031823129
-
Osteoclast-like cells in murine collagen induced arthritis
-
COI: 1:CAS:528:DyaK1cXjvVemtr4%3D, PID: 9632079
-
Suzuki Y, Nishikaku F, Nakatuka M, Koga Y (1998) Osteoclast-like cells in murine collagen induced arthritis. J Rheumatol 25:1154–1160
-
(1998)
J Rheumatol
, vol.25
, pp. 1154-1160
-
-
Suzuki, Y.1
Nishikaku, F.2
Nakatuka, M.3
Koga, Y.4
-
24
-
-
0033850752
-
Expression of osteoclast differentiation factor at sites of bone erosion in collagen-induced arthritis
-
COI: 1:CAS:528:DC%2BD3cXivFOitrs%3D, PID: 10765926
-
Romas E, Bakharevski O, Hards DK et al (2000) Expression of osteoclast differentiation factor at sites of bone erosion in collagen-induced arthritis. Arthritis Rheum 43:821–826
-
(2000)
Arthritis Rheum
, vol.43
, pp. 821-826
-
-
Romas, E.1
Bakharevski, O.2
Hards, D.K.3
-
25
-
-
0031818057
-
Induction of abundant osteoclast-like multinucleated giant cells in adjuvant arthritic rats with accompanying disordered high bone turnover
-
COI: 1:STN:280:DyaK1czlsVGqsg%3D%3D, PID: 9690133
-
Kuratani T, Nagata K, Kukita T, Hotokebuchi T, Nakasima A, Iijima T (1998) Induction of abundant osteoclast-like multinucleated giant cells in adjuvant arthritic rats with accompanying disordered high bone turnover. Histol Histopathol 13:751–759
-
(1998)
Histol Histopathol
, vol.13
, pp. 751-759
-
-
Kuratani, T.1
Nagata, K.2
Kukita, T.3
Hotokebuchi, T.4
Nakasima, A.5
Iijima, T.6
-
26
-
-
0038342686
-
Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice
-
COI: 1:CAS:528:DC%2BD3sXmtFartbY%3D, PID: 12847699
-
Schett G, Redlich K, Hayer S et al (2003) Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice. Arthritis Rheum 48:2042–2051
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2042-2051
-
-
Schett, G.1
Redlich, K.2
Hayer, S.3
-
27
-
-
0036792512
-
Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis
-
COI: 1:CAS:528:DC%2BD38Xotl2jsbg%3D, PID: 12368214
-
Romas E, Sims NA, Hards DK et al (2002) Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis. Am J Pathol 161:1419–1427
-
(2002)
Am J Pathol
, vol.161
, pp. 1419-1427
-
-
Romas, E.1
Sims, N.A.2
Hards, D.K.3
-
28
-
-
3142741595
-
Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis
-
COI: 1:CAS:528:DC%2BD2cXmsVantrs%3D, PID: 15248234
-
Herrak P, Gortz B, Hayer S et al (2004) Zoledronic acid protects against local and systemic bone loss in tumor necrosis factor-mediated arthritis. Arthritis Rheum 50:2327–2337
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2327-2337
-
-
Herrak, P.1
Gortz, B.2
Hayer, S.3
-
29
-
-
3142763806
-
Targeting osteoclasts with zoledronic acid prevents bone destruction in collagen-induced arthritis
-
COI: 1:CAS:528:DC%2BD2cXmsVantrg%3D, PID: 15248235
-
Sims NA, Green JR, Glatt M et al (2004) Targeting osteoclasts with zoledronic acid prevents bone destruction in collagen-induced arthritis. Arthritis Rheum 50:2338–2346
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2338-2346
-
-
Sims, N.A.1
Green, J.R.2
Glatt, M.3
-
30
-
-
33646484359
-
Preliminary evidence for a structural benefit of the new bisphosphonate zoledronic acid in early rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BD28XlsFSqurg%3D, PID: 16645968
-
Jarrett SJ, Conaghan PG, Sloan VS et al (2006) Preliminary evidence for a structural benefit of the new bisphosphonate zoledronic acid in early rheumatoid arthritis. Arthritis Rheum 54:1410–1414
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1410-1414
-
-
Jarrett, S.J.1
Conaghan, P.G.2
Sloan, V.S.3
-
31
-
-
77950451127
-
Denosumab-mediated increase in hand bone mineral density associated with decreased progression of bone erosion in rheumatoid arthritis patients
-
COI: 1:CAS:528:DC%2BC3cXhtFKjs7nI
-
Deodhar A, Dore RK, Mandel D et al (2010) Denosumab-mediated increase in hand bone mineral density associated with decreased progression of bone erosion in rheumatoid arthritis patients. Arthritis Care Res (Hoboken) 62:569–574
-
(2010)
Arthritis Care Res (Hoboken)
, vol.62
, pp. 569-574
-
-
Deodhar, A.1
Dore, R.K.2
Mandel, D.3
-
32
-
-
43949139580
-
Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: a twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial
-
COI: 1:CAS:528:DC%2BD1cXms1ehu70%3D, PID: 18438830
-
Cohen SB, Dore RK, Lane NE et al (2008) Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: a twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial. Arthritis Rheum 58:1299–1309
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1299-1309
-
-
Cohen, S.B.1
Dore, R.K.2
Lane, N.E.3
-
33
-
-
84925533641
-
Three-year denosumab treatment in postmenopausal Japanese women and men with osteoporosis: results from a 1-year open-label extension of the Denosumab Fracture Intervention Randomized Placebo Controlled Trial (DIRECT)
-
COI: 1:CAS:528:DC%2BC2cXitVSgsbbO, PID: 25403903
-
Sugimoto T, Matsumoto T, Hosoi T et al (2015) Three-year denosumab treatment in postmenopausal Japanese women and men with osteoporosis: results from a 1-year open-label extension of the Denosumab Fracture Intervention Randomized Placebo Controlled Trial (DIRECT). Osteoporos Int 26:765–774
-
(2015)
Osteoporos Int
, vol.26
, pp. 765-774
-
-
Sugimoto, T.1
Matsumoto, T.2
Hosoi, T.3
-
34
-
-
14944371405
-
IL-1 mediates TNF-induced osteoclastogenesis
-
COI: 1:CAS:528:DC%2BD2MXhtFyjsLo%3D, PID: 15668736
-
Wei S, Kitaura H, Zhou P, Ross FP, Teitelbaum SL (2005) IL-1 mediates TNF-induced osteoclastogenesis. J Clin Invest 115:282–290
-
(2005)
J Clin Invest
, vol.115
, pp. 282-290
-
-
Wei, S.1
Kitaura, H.2
Zhou, P.3
Ross, F.P.4
Teitelbaum, S.L.5
-
35
-
-
0032055597
-
IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages
-
COI: 1:CAS:528:DyaK1cXitFWqsLs%3D, PID: 9531313
-
Jovanovic DV, Di Battista JA, Martel-Pelletier J et al (1998) IL-17 stimulates the production and expression of proinflammatory cytokines, IL-beta and TNF-alpha, by human macrophages. J Immunol 160:3513–3521
-
(1998)
J Immunol
, vol.160
, pp. 3513-3521
-
-
Jovanovic, D.V.1
Di Battista, J.A.2
Martel-Pelletier, J.3
-
36
-
-
0033134608
-
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
-
COI: 1:CAS:528:DyaK1MXivFans7c%3D, PID: 10225978
-
Kotake S, Udagawa N, Takahashi N et al (1999) IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 103:1345–1352
-
(1999)
J Clin Invest
, vol.103
, pp. 1345-1352
-
-
Kotake, S.1
Udagawa, N.2
Takahashi, N.3
-
37
-
-
0037371262
-
IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balance
-
COI: 1:CAS:528:DC%2BD3sXht12htLc%3D, PID: 12594294
-
Lubberts E, van den Bersselaar L, Oppers-Walgreen B et al (2003) IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balance. J Immunol 170:2655–2662
-
(2003)
J Immunol
, vol.170
, pp. 2655-2662
-
-
Lubberts, E.1
van den Bersselaar, L.2
Oppers-Walgreen, B.3
-
38
-
-
54449101331
-
IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17
-
COI: 1:CAS:528:DC%2BD1cXht1Oisr%2FF
-
Hashizume M, Hayakawa N, Mihara M (2008) IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17. Rheumatology (Oxford) 47:1635–1640
-
(2008)
Rheumatology (Oxford)
, vol.47
, pp. 1635-1640
-
-
Hashizume, M.1
Hayakawa, N.2
Mihara, M.3
-
39
-
-
33744955055
-
Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression
-
COI: 1:CAS:528:DC%2BD28Xjslensrs%3D, PID: 16461346
-
Yao Z, Li P, Zhang Q et al (2006) Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression. J Biol Chem 281:11846–11855
-
(2006)
J Biol Chem
, vol.281
, pp. 11846-11855
-
-
Yao, Z.1
Li, P.2
Zhang, Q.3
-
40
-
-
0033602023
-
Interleukin 1 induces multinucleation and bone-resorbing activity of osteoclasts in the absence of osteoblasts/stromal cells
-
COI: 1:CAS:528:DyaK1MXht12ku7w%3D, PID: 10047450
-
Jimi E, Nakamura I, Duong LT et al (1999) Interleukin 1 induces multinucleation and bone-resorbing activity of osteoclasts in the absence of osteoblasts/stromal cells. Exp Cell Res 247:84–93
-
(1999)
Exp Cell Res
, vol.247
, pp. 84-93
-
-
Jimi, E.1
Nakamura, I.2
Duong, L.T.3
-
41
-
-
78649732752
-
Intercellular adhesion molecule-1 on synovial cells attenuated interleukin-6-induced inhibition of osteoclastogenesis induced by receptor activator for nuclear factor kappaB ligand
-
COI: 1:CAS:528:DC%2BC3MXnvFSmug%3D%3D, PID: 21039424
-
Suzuki M, Hashizume M, Yoshida H, Shiina M, Mihara M (2011) Intercellular adhesion molecule-1 on synovial cells attenuated interleukin-6-induced inhibition of osteoclastogenesis induced by receptor activator for nuclear factor kappaB ligand. Clin Exp Immunol 163:88–95
-
(2011)
Clin Exp Immunol
, vol.163
, pp. 88-95
-
-
Suzuki, M.1
Hashizume, M.2
Yoshida, H.3
Shiina, M.4
Mihara, M.5
-
42
-
-
45549097409
-
Interleukin-6 directly inhibits osteoclast differentiation by suppressing receptor activator of NF-kappaB signaling pathways
-
COI: 1:CAS:528:DC%2BD1cXkvVSgtL0%3D, PID: 18296709
-
Yoshitake F, Itoh S, Narita H, Ishihara K, Ebisu S (2008) Interleukin-6 directly inhibits osteoclast differentiation by suppressing receptor activator of NF-kappaB signaling pathways. J Biol Chem 283:11535–11540
-
(2008)
J Biol Chem
, vol.283
, pp. 11535-11540
-
-
Yoshitake, F.1
Itoh, S.2
Narita, H.3
Ishihara, K.4
Ebisu, S.5
-
43
-
-
69449090213
-
Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo
-
COI: 1:CAS:528:DC%2BD1MXht1WhtLbJ, PID: 19714627
-
Axmann R, Bohm C, Kronke G, Zwerina J, Smolen J, Schett G (2009) Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo. Arthritis Rheum 60:2747–2756
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2747-2756
-
-
Axmann, R.1
Bohm, C.2
Kronke, G.3
Zwerina, J.4
Smolen, J.5
Schett, G.6
-
44
-
-
0033393367
-
Interleukin 6 knock-out mice are resistant to antigen-induced experimental arthritis
-
COI: 1:CAS:528:DC%2BD3cXht1CjsA%3D%3D, PID: 10623431
-
Boe A, Baiocchi M, Carbonatto M, Papoian R, Serlupi-Crescenzi O (1999) Interleukin 6 knock-out mice are resistant to antigen-induced experimental arthritis. Cytokine 11:1057–1064
-
(1999)
Cytokine
, vol.11
, pp. 1057-1064
-
-
Boe, A.1
Baiocchi, M.2
Carbonatto, M.3
Papoian, R.4
Serlupi-Crescenzi, O.5
-
45
-
-
13344250490
-
Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation
-
COI: 1:CAS:528:DyaK28Xht1Gnurw%3D, PID: 8770701
-
Kotake S, Sato K, Kim KJ et al (1996) Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation. J Bone Miner Res 11:88–95
-
(1996)
J Bone Miner Res
, vol.11
, pp. 88-95
-
-
Kotake, S.1
Sato, K.2
Kim, K.J.3
-
46
-
-
0032429668
-
Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis
-
COI: 1:CAS:528:DyaK1MXksl2gtg%3D%3D, PID: 9870868
-
Takagi N, Mihara M, Moriya Y et al (1998) Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis. Arthritis Rheum 41:2117–2121
-
(1998)
Arthritis Rheum
, vol.41
, pp. 2117-2121
-
-
Takagi, N.1
Mihara, M.2
Moriya, Y.3
-
47
-
-
34247214078
-
Bone erosions and bone marrow edema as defined by magnetic resonance imaging reflect true bone marrow inflammation in rheumatoid arthritis
-
PID: 17393390
-
Jimenez-Boj E, Nobauer-Huhmann I, Hanslik-Schnabel B et al (2007) Bone erosions and bone marrow edema as defined by magnetic resonance imaging reflect true bone marrow inflammation in rheumatoid arthritis. Arthritis Rheum 56:1118–1124
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1118-1124
-
-
Jimenez-Boj, E.1
Nobauer-Huhmann, I.2
Hanslik-Schnabel, B.3
-
48
-
-
45349090842
-
Magnetic resonance imaging findings in 84 patients with early rheumatoid arthritis: bone marrow oedema predicts erosive progression
-
COI: 1:STN:280:DC%2BD1czgvFSqtw%3D%3D, PID: 17981915
-
Haavardsholm EA, Boyesen P, Ostergaard M, Schildvold A, Kvien TK (2008) Magnetic resonance imaging findings in 84 patients with early rheumatoid arthritis: bone marrow oedema predicts erosive progression. Ann Rheum Dis 67:794–800
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 794-800
-
-
Haavardsholm, E.A.1
Boyesen, P.2
Ostergaard, M.3
Schildvold, A.4
Kvien, T.K.5
-
49
-
-
61549139043
-
MRI bone oedema is the strongest predictor of subsequent radiographic progression in early rheumatoid arthritis. Results from a 2-year randomised controlled trial (CIMESTRA)
-
COI: 1:CAS:528:DC%2BD1MXjs1WitLY%3D, PID: 18388160
-
Hetland ML, Ejbjerg B, Horslev-Petersen K et al (2009) MRI bone oedema is the strongest predictor of subsequent radiographic progression in early rheumatoid arthritis. Results from a 2-year randomised controlled trial (CIMESTRA). Ann Rheum Dis 68:384–390
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 384-390
-
-
Hetland, M.L.1
Ejbjerg, B.2
Horslev-Petersen, K.3
-
50
-
-
58849124261
-
Cellular characterisation of magnetic resonance imaging bone oedema in rheumatoid arthritis; implications for pathogenesis of erosive disease
-
COI: 1:STN:280:DC%2BD1M%2FmsFSquw%3D%3D, PID: 18765428
-
Dalbeth N, Smith T, Gray S et al (2009) Cellular characterisation of magnetic resonance imaging bone oedema in rheumatoid arthritis; implications for pathogenesis of erosive disease. Ann Rheum Dis 68:279–282
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 279-282
-
-
Dalbeth, N.1
Smith, T.2
Gray, S.3
-
51
-
-
33644895018
-
Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: results from the ASPIRE trial
-
COI: 1:CAS:528:DC%2BD28XjtV2ls74%3D, PID: 16508926
-
Smolen JS, Van Der Heijde DM, St Clair EW et al (2006) Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: results from the ASPIRE trial. Arthritis Rheum 54:702–710
-
(2006)
Arthritis Rheum
, vol.54
, pp. 702-710
-
-
Smolen, J.S.1
Van Der Heijde, D.M.2
St Clair, E.W.3
-
52
-
-
34447300492
-
Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab
-
COI: 1:CAS:528:DC%2BD2sXhtVKltL7O, PID: 17485422
-
Nishimoto N, Hashimoto J, Miyasaka N et al (2007) Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab. Ann Rheum Dis 66:1162–1167
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 1162-1167
-
-
Nishimoto, N.1
Hashimoto, J.2
Miyasaka, N.3
-
53
-
-
84864716411
-
Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC38Xht1SisrbI, PID: 22873530
-
Fleischmann R, Kremer J, Cush J et al (2012) Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis. N Engl J Med 367:495–507
-
(2012)
N Engl J Med
, vol.367
, pp. 495-507
-
-
Fleischmann, R.1
Kremer, J.2
Cush, J.3
-
54
-
-
84864703156
-
Tofacitinib or adalimumab versus placebo in rheumatoid arthritis
-
PID: 22873531
-
van Vollenhoven RF, Fleischmann R, Cohen S et al (2012) Tofacitinib or adalimumab versus placebo in rheumatoid arthritis. N Engl J Med 367:508–519
-
(2012)
N Engl J Med
, vol.367
, pp. 508-519
-
-
van Vollenhoven, R.F.1
Fleischmann, R.2
Cohen, S.3
-
55
-
-
84902593564
-
Tofacitinib versus methotrexate in rheumatoid arthritis
-
PID: 24941177
-
Lee EB, Fleischmann R, Hall S et al (2014) Tofacitinib versus methotrexate in rheumatoid arthritis. N Engl J Med 370:2377–2386
-
(2014)
N Engl J Med
, vol.370
, pp. 2377-2386
-
-
Lee, E.B.1
Fleischmann, R.2
Hall, S.3
-
56
-
-
10444241015
-
Predicting erosive disease in rheumatoid arthritis. A longitudinal study of changes in bone density using digital X-ray radiogrammetry: a pilot study
-
COI: 1:STN:280:DC%2BD2crpt1WqsA%3D%3D
-
Stewart A, Mackenzie LM, Black AJ, Reid DM (2004) Predicting erosive disease in rheumatoid arthritis. A longitudinal study of changes in bone density using digital X-ray radiogrammetry: a pilot study. Rheumatology (Oxford) 43:1561–1564
-
(2004)
Rheumatology (Oxford)
, vol.43
, pp. 1561-1564
-
-
Stewart, A.1
Mackenzie, L.M.2
Black, A.J.3
Reid, D.M.4
-
57
-
-
0021969110
-
Quantitative histologic studies on the pathogenesis of periarticular osteoporosis in rheumatoid arthritis
-
COI: 1:STN:280:DyaL2M%2FpslWhsA%3D%3D, PID: 3966938
-
Shimizu S, Shiozawa S, Shiozawa K, Imura S, Fujita T (1985) Quantitative histologic studies on the pathogenesis of periarticular osteoporosis in rheumatoid arthritis. Arthritis Rheum 28:25–31
-
(1985)
Arthritis Rheum
, vol.28
, pp. 25-31
-
-
Shimizu, S.1
Shiozawa, S.2
Shiozawa, K.3
Imura, S.4
Fujita, T.5
-
58
-
-
34250626806
-
Meta-analysis: diagnostic accuracy of anti-cyclic citrullinated peptide antibody and rheumatoid factor for rheumatoid arthritis
-
PID: 17548411
-
Nishimura K, Sugiyama D, Kogata Y et al (2007) Meta-analysis: diagnostic accuracy of anti-cyclic citrullinated peptide antibody and rheumatoid factor for rheumatoid arthritis. Ann Intern Med 146:797–808
-
(2007)
Ann Intern Med
, vol.146
, pp. 797-808
-
-
Nishimura, K.1
Sugiyama, D.2
Kogata, Y.3
-
59
-
-
84873988058
-
Baseline anti-citrullinated peptide antibody (ACPA) titers and serum interleukin-6 (IL-6) levels possibly predict progression of bone destruction in early stages of rheumatoid arthritis (ERA)
-
COI: 1:CAS:528:DC%2BC3sXhvV2ls7g%3D, PID: 22457007
-
Saeki Y, Kudo-Tanaka E, Ohshima S et al (2013) Baseline anti-citrullinated peptide antibody (ACPA) titers and serum interleukin-6 (IL-6) levels possibly predict progression of bone destruction in early stages of rheumatoid arthritis (ERA). Rheumatol Int 33:451–456
-
(2013)
Rheumatol Int
, vol.33
, pp. 451-456
-
-
Saeki, Y.1
Kudo-Tanaka, E.2
Ohshima, S.3
-
60
-
-
84954374409
-
-
Additive effect of anti-citrullinated protein antibodies and rheumatoid factor on bone erosions in patients with RA
-
Hecht C., Englbrecht M., Rech J., et al. (2014) Additive effect of anti-citrullinated protein antibodies and rheumatoid factor on bone erosions in patients with RA. Ann Rheum Dis. doi:10.1136/annrheumdis-2014-205428
-
(2014)
Ann Rheum Dis
-
-
Hecht, C.1
Englbrecht, M.2
Rech, J.3
-
62
-
-
70350475800
-
Immune complexes from rheumatoid arthritis synovial fluid induce FcgammaRIIa dependent and rheumatoid factor correlated production of tumour necrosis factor-alpha by peripheral blood mononuclear cells
-
PID: 16569263
-
Mathsson L, Lampa J, Mullazehi M, Ronnelid J (2006) Immune complexes from rheumatoid arthritis synovial fluid induce FcgammaRIIa dependent and rheumatoid factor correlated production of tumour necrosis factor-alpha by peripheral blood mononuclear cells. Arthritis Res Ther 8:R64
-
(2006)
Arthritis Res Ther
, vol.8
, pp. R64
-
-
Mathsson, L.1
Lampa, J.2
Mullazehi, M.3
Ronnelid, J.4
-
63
-
-
40549142075
-
Induction of macrophage secretion of tumor necrosis factor alpha through Fcgamma receptor IIa engagement by rheumatoid arthritis-specific autoantibodies to citrullinated proteins complexed with fibrinogen
-
COI: 1:CAS:528:DC%2BD1cXjslWqur0%3D, PID: 18311806
-
Clavel C, Nogueira L, Laurent L et al (2008) Induction of macrophage secretion of tumor necrosis factor alpha through Fcgamma receptor IIa engagement by rheumatoid arthritis-specific autoantibodies to citrullinated proteins complexed with fibrinogen. Arthritis Rheum 58:678–688
-
(2008)
Arthritis Rheum
, vol.58
, pp. 678-688
-
-
Clavel, C.1
Nogueira, L.2
Laurent, L.3
-
64
-
-
77951726471
-
Anti-citrullinated protein antibodies bind surface-expressed citrullinated Grp78 on monocyte/macrophages and stimulate tumor necrosis factor alpha production
-
COI: 1:CAS:528:DC%2BC3cXhtFGnu7jP, PID: 20213805
-
Lu MC, Lai NS, Yu HC, Huang HB, Hsieh SC, Yu CL (2010) Anti-citrullinated protein antibodies bind surface-expressed citrullinated Grp78 on monocyte/macrophages and stimulate tumor necrosis factor alpha production. Arthritis Rheum 62:1213–1223
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1213-1223
-
-
Lu, M.C.1
Lai, N.S.2
Yu, H.C.3
Huang, H.B.4
Hsieh, S.C.5
Yu, C.L.6
-
65
-
-
84860561645
-
Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin
-
COI: 1:CAS:528:DC%2BC38Xmsl2js7g%3D, PID: 22505457
-
Harre U, Georgess D, Bang H et al (2012) Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin. J Clin Invest 122:1791–1802
-
(2012)
J Clin Invest
, vol.122
, pp. 1791-1802
-
-
Harre, U.1
Georgess, D.2
Bang, H.3
-
66
-
-
84879542387
-
Inflammatory monocytes and Fcgamma receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice
-
COI: 1:CAS:528:DC%2BC3sXhtFejs7vE, PID: 23754379
-
Seeling M, Hillenhoff U, David JP et al (2013) Inflammatory monocytes and Fcgamma receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice. Proc Natl Acad Sci U S A 110:10729–10734
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 10729-10734
-
-
Seeling, M.1
Hillenhoff, U.2
David, J.P.3
-
67
-
-
84926378835
-
Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss
-
COI: 1:CAS:528:DC%2BC2MXhtF2ksrjE, PID: 25825024
-
Harre U, Lang SC, Pfeifle R et al (2015) Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss. Nat Commun 6:6651
-
(2015)
Nat Commun
, vol.6
, pp. 6651
-
-
Harre, U.1
Lang, S.C.2
Pfeifle, R.3
-
68
-
-
33746888249
-
Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation
-
COI: 1:CAS:528:DC%2BD28Xnsl2hsbY%3D, PID: 16888140
-
Kaneko Y, Nimmerjahn F, Ravetch JV (2006) Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation. Science 313:670–673
-
(2006)
Science
, vol.313
, pp. 670-673
-
-
Kaneko, Y.1
Nimmerjahn, F.2
Ravetch, J.V.3
-
69
-
-
7044269900
-
A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BD2cXkvVOhur4%3D, PID: 15225365
-
Berglin E, Padyukov L, Sundin U et al (2004) A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis. Arthritis Res Ther 6:R303–308
-
(2004)
Arthritis Res Ther
, vol.6
, pp. R303-R308
-
-
Berglin, E.1
Padyukov, L.2
Sundin, U.3
-
70
-
-
1042290337
-
Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors
-
PID: 14872479
-
Nielen MM, van Schaardenburg D, Reesink HW et al (2004) Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors. Arthritis Rheum 50:380–386
-
(2004)
Arthritis Rheum
, vol.50
, pp. 380-386
-
-
Nielen, M.M.1
van Schaardenburg, D.2
Reesink, H.W.3
-
71
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
COI: 1:CAS:528:DC%2BD2cXhtVals7o%3D, PID: 14744438
-
Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281–297
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
72
-
-
38349169664
-
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
-
COI: 1:CAS:528:DC%2BD1cXnt1ensA%3D%3D, PID: 18197166
-
Filipowicz W, Bhattacharyya SN, Sonenberg N (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9:102–114
-
(2008)
Nat Rev Genet
, vol.9
, pp. 102-114
-
-
Filipowicz, W.1
Bhattacharyya, S.N.2
Sonenberg, N.3
-
73
-
-
84862169420
-
Horizontal transfer of microRNAs: molecular mechanisms and clinical applications
-
COI: 1:CAS:528:DC%2BC38XitFCms70%3D, PID: 22314808
-
Chen X, Liang H, Zhang J, Zen K, Zhang CY (2012) Horizontal transfer of microRNAs: molecular mechanisms and clinical applications. Protein Cell 3:28–37
-
(2012)
Protein Cell
, vol.3
, pp. 28-37
-
-
Chen, X.1
Liang, H.2
Zhang, J.3
Zen, K.4
Zhang, C.Y.5
-
74
-
-
84862777377
-
Secreted microRNAs: a new form of intercellular communication
-
COI: 1:CAS:528:DC%2BC38XjsVCgsb8%3D, PID: 22260888
-
Chen X, Liang H, Zhang J, Zen K, Zhang CY (2012) Secreted microRNAs: a new form of intercellular communication. Trends Cell Biol 22:125–132
-
(2012)
Trends Cell Biol
, vol.22
, pp. 125-132
-
-
Chen, X.1
Liang, H.2
Zhang, J.3
Zen, K.4
Zhang, C.Y.5
-
75
-
-
81055157988
-
Exosome secretion: molecular mechanisms and roles in immune responses
-
COI: 1:CAS:528:DC%2BC3MXhs1SqtrbJ, PID: 21645191
-
Bobrie A, Colombo M, Raposo G, Thery C (2011) Exosome secretion: molecular mechanisms and roles in immune responses. Traffic 12:1659–1668
-
(2011)
Traffic
, vol.12
, pp. 1659-1668
-
-
Bobrie, A.1
Colombo, M.2
Raposo, G.3
Thery, C.4
-
76
-
-
79955070767
-
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells
-
PID: 21505438
-
Mittelbrunn M, Gutierrez-Vazquez C, Villarroya-Beltri C et al (2011) Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. Nat Commun 2:282
-
(2011)
Nat Commun
, vol.2
, pp. 282
-
-
Mittelbrunn, M.1
Gutierrez-Vazquez, C.2
Villarroya-Beltri, C.3
-
77
-
-
84875846330
-
BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression
-
COI: 1:CAS:528:DC%2BC3sXlvVKhsLo%3D, PID: 23454749
-
Roccaro AM, Sacco A, Maiso P et al (2013) BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression. J Clin Invest 123:1542–1555
-
(2013)
J Clin Invest
, vol.123
, pp. 1542-1555
-
-
Roccaro, A.M.1
Sacco, A.2
Maiso, P.3
-
78
-
-
79955846123
-
miRNAs and rheumatoid arthritis - promising novel biomarkers
-
PID: 21416408
-
Duroux-Richard I, Jorgensen C, Apparailly F (2011) miRNAs and rheumatoid arthritis - promising novel biomarkers. Swiss Med Wkly 141:w13175
-
(2011)
Swiss Med Wkly
, vol.141
, pp. w13175
-
-
Duroux-Richard, I.1
Jorgensen, C.2
Apparailly, F.3
-
79
-
-
79958053053
-
The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis
-
COI: 1:CAS:528:DC%2BC3MXmslOkurk%3D, PID: 21425254
-
Nakasa T, Shibuya H, Nagata Y, Niimoto T, Ochi M (2011) The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis. Arthritis Rheum 63:1582–1590
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1582-1590
-
-
Nakasa, T.1
Shibuya, H.2
Nagata, Y.3
Niimoto, T.4
Ochi, M.5
-
80
-
-
80052452625
-
MicroRNAs in rheumatoid arthritis
-
COI: 1:CAS:528:DC%2BC3MXhsFSis7%2FI, PID: 21600203
-
Ceribelli A, Nahid MA, Satoh M, Chan EK (2011) MicroRNAs in rheumatoid arthritis. FEBS Lett 585:3667–3674
-
(2011)
FEBS Lett
, vol.585
, pp. 3667-3674
-
-
Ceribelli, A.1
Nahid, M.A.2
Satoh, M.3
Chan, E.K.4
-
81
-
-
84863686039
-
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-alpha
-
COI: 1:CAS:528:DC%2BC38XnvVyrs7Y%3D, PID: 22660635
-
Zhu S, Pan W, Song X et al (2012) The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-alpha. Nat Med 18:1077–1086
-
(2012)
Nat Med
, vol.18
, pp. 1077-1086
-
-
Zhu, S.1
Pan, W.2
Song, X.3
-
82
-
-
79960595150
-
MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis
-
COI: 1:CAS:528:DC%2BC3MXptV2hurs%3D, PID: 21690378
-
Kurowska-Stolarska M, Alivernini S, Ballantine LE et al (2011) MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proc Natl Acad Sci U S A 108:11193–11198
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 11193-11198
-
-
Kurowska-Stolarska, M.1
Alivernini, S.2
Ballantine, L.E.3
-
83
-
-
38049030287
-
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
-
COI: 1:CAS:528:DC%2BD2sXhtFWitrvM, PID: 17911593
-
Tili E, Michaille JJ, Cimino A et al (2007) Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol 179:5082–5089
-
(2007)
J Immunol
, vol.179
, pp. 5082-5089
-
-
Tili, E.1
Michaille, J.J.2
Cimino, A.3
-
84
-
-
79955561084
-
Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice
-
PID: 21321928
-
Bluml S, Bonelli M, Niederreiter B et al (2011) Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice. Arthritis Rheum 63:1281–1288
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1281-1288
-
-
Bluml, S.1
Bonelli, M.2
Niederreiter, B.3
-
85
-
-
79953686494
-
A microRNA expression signature of osteoclastogenesis
-
COI: 1:CAS:528:DC%2BC3MXkslagurw%3D, PID: 21273303
-
Sugatani T, Vacher J, Hruska KA (2011) A microRNA expression signature of osteoclastogenesis. Blood 117:3648–3657
-
(2011)
Blood
, vol.117
, pp. 3648-3657
-
-
Sugatani, T.1
Vacher, J.2
Hruska, K.A.3
-
86
-
-
84866596352
-
Interferon-beta-induced miR-155 inhibits osteoclast differentiation by targeting SOCS1 and MITF
-
COI: 1:CAS:528:DC%2BC38XhtVymt7%2FK, PID: 22771905
-
Zhang J, Zhao H, Chen J et al (2012) Interferon-beta-induced miR-155 inhibits osteoclast differentiation by targeting SOCS1 and MITF. FEBS Lett 586:3255–3262
-
(2012)
FEBS Lett
, vol.586
, pp. 3255-3262
-
-
Zhang, J.1
Zhao, H.2
Chen, J.3
-
87
-
-
84939179482
-
NF-kappaB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation
-
PID: 25601191
-
de la Rica L, Garcia-Gomez A, Comet NR et al (2015) NF-kappaB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation. Genome Biol 16:2
-
(2015)
Genome Biol
, vol.16
, pp. 2
-
-
de la Rica, L.1
Garcia-Gomez, A.2
Comet, N.R.3
-
88
-
-
84958989804
-
MicroRNA-124 inhibits the progression of adjuvant-induced arthritis in rats. Ann Rheum Dis
-
Nakamachi Y., Ohnuma K., Uto K., Noguchi Y., Saegusa J., Kawano S. (2015) MicroRNA-124 inhibits the progression of adjuvant-induced arthritis in rats. Ann Rheum Dis. doi:10.1136/annrheumdis-2014-206417
-
(2015)
Ann Rheum Dis
-
-
Nakamachi, Y.1
Ohnuma, K.2
Uto, K.3
Noguchi, Y.4
Saegusa, J.5
Kawano, S.6
-
89
-
-
84893845161
-
Bone marrow mesenchymal stem cells and TGF-beta signaling in bone remodeling
-
COI: 1:CAS:528:DC%2BC2cXis1eku7o%3D, PID: 24487640
-
Crane JL, Cao X (2014) Bone marrow mesenchymal stem cells and TGF-beta signaling in bone remodeling. J Clin Invest 124:466–472
-
(2014)
J Clin Invest
, vol.124
, pp. 466-472
-
-
Crane, J.L.1
Cao, X.2
-
90
-
-
84155188831
-
Update on Wnt signaling in bone cell biology and bone disease
-
COI: 1:CAS:528:DC%2BC3MXhs1Krur%2FO, PID: 22079544
-
Monroe DG, McGee-Lawrence ME, Oursler MJ, Westendorf JJ (2012) Update on Wnt signaling in bone cell biology and bone disease. Gene 492:1–18
-
(2012)
Gene
, vol.492
, pp. 1-18
-
-
Monroe, D.G.1
McGee-Lawrence, M.E.2
Oursler, M.J.3
Westendorf, J.J.4
-
91
-
-
84943659307
-
Bone morphogenetic protein signaling in bone homeostasis. Bone
-
Sanchez-Duffhues G., Hiepen C., Knaus P., Ten Dijke P. (2015) Bone morphogenetic protein signaling in bone homeostasis. Bone. doi:10.1016/j.bone.2015.05.025
-
(2015)
Bone
-
-
Sanchez-Duffhues, G.1
Hiepen, C.2
Knaus, P.3
Ten Dijke, P.4
-
93
-
-
33646856033
-
Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass
-
COI: 1:CAS:528:DC%2BD28XlvVamu7o%3D, PID: 16753024
-
Morvan F, Boulukos K, Clement-Lacroix P et al (2006) Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass. J Bone Miner Res 21:934–945
-
(2006)
J Bone Miner Res
, vol.21
, pp. 934-945
-
-
Morvan, F.1
Boulukos, K.2
Clement-Lacroix, P.3
-
94
-
-
33748156090
-
Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia
-
COI: 1:CAS:528:DC%2BD28XpsVOhtL4%3D, PID: 16730481
-
Li J, Sarosi I, Cattley RC et al (2006) Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. Bone 39:754–766
-
(2006)
Bone
, vol.39
, pp. 754-766
-
-
Li, J.1
Sarosi, I.2
Cattley, R.C.3
-
95
-
-
2342529836
-
The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice
-
COI: 1:CAS:528:DC%2BD2cXjvVOkt70%3D, PID: 14976225
-
Bodine PV, Zhao W, Kharode YP et al (2004) The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice. Mol Endocrinol 18:1222–1237
-
(2004)
Mol Endocrinol
, vol.18
, pp. 1222-1237
-
-
Bodine, P.V.1
Zhao, W.2
Kharode, Y.P.3
-
96
-
-
77951998251
-
Overexpression of secreted frizzled-related protein 1 inhibits bone formation and attenuates parathyroid hormone bone anabolic effects
-
COI: 1:CAS:528:DC%2BC3cXksl2ks7w%3D, PID: 19594295
-
Yao W, Cheng Z, Shahnazari M, Dai W, Johnson ML, Lane NE (2010) Overexpression of secreted frizzled-related protein 1 inhibits bone formation and attenuates parathyroid hormone bone anabolic effects. J Bone Miner Res 25:190–199
-
(2010)
J Bone Miner Res
, vol.25
, pp. 190-199
-
-
Yao, W.1
Cheng, Z.2
Shahnazari, M.3
Dai, W.4
Johnson, M.L.5
Lane, N.E.6
-
97
-
-
33846949349
-
Dickkopf-1 is a master regulator of joint remodeling
-
COI: 1:CAS:528:DC%2BD2sXhsVyktbY%3D, PID: 17237793
-
Diarra D, Stolina M, Polzer K et al (2007) Dickkopf-1 is a master regulator of joint remodeling. Nat Med 13:156–163
-
(2007)
Nat Med
, vol.13
, pp. 156-163
-
-
Diarra, D.1
Stolina, M.2
Polzer, K.3
-
98
-
-
80755189018
-
The emerging role of Dickkopf-1 in bone biology: is it the main switch controlling bone and joint remodeling?
-
COI: 1:CAS:528:DC%2BC3MXhsVSqsbjJ, PID: 21435697
-
Daoussis D, Andonopoulos AP (2011) The emerging role of Dickkopf-1 in bone biology: is it the main switch controlling bone and joint remodeling? Semin Arthritis Rheum 41:170–177
-
(2011)
Semin Arthritis Rheum
, vol.41
, pp. 170-177
-
-
Daoussis, D.1
Andonopoulos, A.P.2
-
99
-
-
84860461357
-
Resolution of inflammation induces osteoblast function and regulates the Wnt signaling pathway
-
COI: 1:CAS:528:DC%2BC38XmtFWgsrY%3D, PID: 22139865
-
Matzelle MM, Gallant MA, Condon KW et al (2012) Resolution of inflammation induces osteoblast function and regulates the Wnt signaling pathway. Arthritis Rheum 64:1540–1550
-
(2012)
Arthritis Rheum
, vol.64
, pp. 1540-1550
-
-
Matzelle, M.M.1
Gallant, M.A.2
Condon, K.W.3
-
100
-
-
21244480924
-
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
-
COI: 1:CAS:528:DC%2BD2MXktFylsbs%3D, PID: 15778503
-
Li X, Zhang Y, Kang H et al (2005) Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. J Biol Chem 280:19883–19887
-
(2005)
J Biol Chem
, vol.280
, pp. 19883-19887
-
-
Li, X.1
Zhang, Y.2
Kang, H.3
-
101
-
-
18444400214
-
A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population
-
PID: 12116252
-
Staehling-Hampton K, Proll S, Paeper BW et al (2002) A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population. Am J Med Genet 110:144–152
-
(2002)
Am J Med Genet
, vol.110
, pp. 144-152
-
-
Staehling-Hampton, K.1
Proll, S.2
Paeper, B.W.3
-
102
-
-
18244403197
-
Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease
-
COI: 1:CAS:528:DC%2BD38XitV2itbo%3D, PID: 11836356
-
Balemans W, Patel N, Ebeling M et al (2002) Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease. J Med Genet 39:91–97
-
(2002)
J Med Genet
, vol.39
, pp. 91-97
-
-
Balemans, W.1
Patel, N.2
Ebeling, M.3
-
103
-
-
84875343487
-
Van Buchem disease: clinical, biochemical, and densitometric features of patients and disease carriers
-
PID: 23074140
-
van Lierop AH, Hamdy NA, van Egmond ME, Bakker E, Dikkers FG, Papapoulos SE (2013) Van Buchem disease: clinical, biochemical, and densitometric features of patients and disease carriers. J Bone Miner Res 28:848–854
-
(2013)
J Bone Miner Res
, vol.28
, pp. 848-854
-
-
van Lierop, A.H.1
Hamdy, N.A.2
van Egmond, M.E.3
Bakker, E.4
Dikkers, F.G.5
Papapoulos, S.E.6
-
104
-
-
0035282968
-
Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)
-
COI: 1:CAS:528:DC%2BD3MXhslSitbw%3D, PID: 11181578
-
Balemans W, Ebeling M, Patel N et al (2001) Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST). Hum Mol Genet 10:537–543
-
(2001)
Hum Mol Genet
, vol.10
, pp. 537-543
-
-
Balemans, W.1
Ebeling, M.2
Patel, N.3
-
105
-
-
0041630893
-
The natural history of sclerosteosis
-
COI: 1:STN:280:DC%2BD3s7ns1eqsg%3D%3D, PID: 12694228
-
Hamersma H, Gardner J, Beighton P (2003) The natural history of sclerosteosis. Clin Genet 63:192–197
-
(2003)
Clin Genet
, vol.63
, pp. 192-197
-
-
Hamersma, H.1
Gardner, J.2
Beighton, P.3
-
106
-
-
44449099165
-
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
-
PID: 18269310
-
Li X, Ominsky MS, Niu QT et al (2008) Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength. J Bone Miner Res 23:860–869
-
(2008)
J Bone Miner Res
, vol.23
, pp. 860-869
-
-
Li, X.1
Ominsky, M.S.2
Niu, Q.T.3
-
107
-
-
10744221383
-
Osteocyte control of bone formation via sclerostin, a novel BMP antagonist
-
COI: 1:CAS:528:DC%2BD3sXpvVemsb4%3D, PID: 14633986
-
Winkler DG, Sutherland MK, Geoghegan JC et al (2003) Osteocyte control of bone formation via sclerostin, a novel BMP antagonist. EMBO J 22:6267–6276
-
(2003)
EMBO J
, vol.22
, pp. 6267-6276
-
-
Winkler, D.G.1
Sutherland, M.K.2
Geoghegan, J.C.3
-
108
-
-
84863040008
-
TGF-beta and BMP signaling in osteoblast differentiation and bone formation
-
COI: 1:CAS:528:DC%2BC38XisFCjsr0%3D, PID: 22298955
-
Chen G, Deng C, Li YP (2012) TGF-beta and BMP signaling in osteoblast differentiation and bone formation. Int J Biol Sci 8:272–288
-
(2012)
Int J Biol Sci
, vol.8
, pp. 272-288
-
-
Chen, G.1
Deng, C.2
Li, Y.P.3
-
109
-
-
77649187445
-
Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse
-
COI: 1:CAS:528:DC%2BC3cXivFGrt78%3D, PID: 20079730
-
Gaur T, Hussain S, Mudhasani R et al (2010) Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse. Dev Biol 340:10–21
-
(2010)
Dev Biol
, vol.340
, pp. 10-21
-
-
Gaur, T.1
Hussain, S.2
Mudhasani, R.3
-
110
-
-
84862624955
-
miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2
-
COI: 1:CAS:528:DC%2BC38XnsVSrtbY%3D, PID: 22564414
-
Wei J, Shi Y, Zheng L et al (2012) miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol 197:509–521
-
(2012)
J Cell Biol
, vol.197
, pp. 509-521
-
-
Wei, J.1
Shi, Y.2
Zheng, L.3
-
111
-
-
84862777464
-
MicroRNA control of bone formation and homeostasis
-
COI: 1:CAS:528:DC%2BC38Xkt1Chsrc%3D, PID: 22290358
-
Lian JB, Stein GS, van Wijnen AJ et al (2012) MicroRNA control of bone formation and homeostasis. Nat Rev Endocrinol 8:212–227
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 212-227
-
-
Lian, J.B.1
Stein, G.S.2
van Wijnen, A.J.3
-
112
-
-
78650548873
-
A network connecting Runx2, SATB2, and the miR-23a ∼ 27a ∼ 24-2 cluster regulates the osteoblast differentiation program
-
COI: 1:CAS:528:DC%2BC3cXhsVyjt7bP, PID: 20980664
-
Hassan MQ, Gordon JA, Beloti MM et al (2010) A network connecting Runx2, SATB2, and the miR-23a ∼ 27a ∼ 24-2 cluster regulates the osteoblast differentiation program. Proc Natl Acad Sci U S A 107:19879–19884
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 19879-19884
-
-
Hassan, M.Q.1
Gordon, J.A.2
Beloti, M.M.3
-
113
-
-
70349504171
-
Erosive progression is minimal, but erosion healing rare, in patients with rheumatoid arthritis treated with adalimumab. A 1 year investigator-initiated follow-up study using high-resolution computed tomography as the primary outcome measure
-
PID: 19019887
-
Moller DU, Boonen A, Hetland ML et al (2009) Erosive progression is minimal, but erosion healing rare, in patients with rheumatoid arthritis treated with adalimumab. A 1 year investigator-initiated follow-up study using high-resolution computed tomography as the primary outcome measure. Ann Rheum Dis 68:1585–1590
-
(2009)
Ann Rheum Dis
, vol.68
, pp. 1585-1590
-
-
Moller, D.U.1
Boonen, A.2
Hetland, M.L.3
-
114
-
-
78751695115
-
No overall progression and occasional repair of erosions despite persistent inflammation in adalimumab-treated rheumatoid arthritis patients: results from a longitudinal comparative MRI, ultrasonography, CT and radiography study
-
PID: 20980282
-
Dohn UM, Ejbjerg B, Boonen A et al (2011) No overall progression and occasional repair of erosions despite persistent inflammation in adalimumab-treated rheumatoid arthritis patients: results from a longitudinal comparative MRI, ultrasonography, CT and radiography study. Ann Rheum Dis 70:252–258
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 252-258
-
-
Dohn, U.M.1
Ejbjerg, B.2
Boonen, A.3
-
115
-
-
80051474129
-
Repair of bone erosions in rheumatoid arthritis treated with tumour necrosis factor inhibitors is based on bone apposition at the base of the erosion
-
COI: 1:CAS:528:DC%2BC3MXht1Cru7rP, PID: 21622765
-
Finzel S, Rech J, Schmidt S et al (2011) Repair of bone erosions in rheumatoid arthritis treated with tumour necrosis factor inhibitors is based on bone apposition at the base of the erosion. Ann Rheum Dis 70:1587–1593
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1587-1593
-
-
Finzel, S.1
Rech, J.2
Schmidt, S.3
-
116
-
-
84873720321
-
Interleukin-6 receptor blockade induces limited repair of bone erosions in rheumatoid arthritis: a micro CT study
-
COI: 1:CAS:528:DC%2BC3sXjvFOjur4%3D, PID: 22586162
-
Finzel S, Rech J, Schmidt S, Engelke K, Englbrecht M, Schett G (2013) Interleukin-6 receptor blockade induces limited repair of bone erosions in rheumatoid arthritis: a micro CT study. Ann Rheum Dis 72:396–400
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 396-400
-
-
Finzel, S.1
Rech, J.2
Schmidt, S.3
Engelke, K.4
Englbrecht, M.5
Schett, G.6
-
117
-
-
0033695186
-
Inhibition of osteoblast differentiation by tumor necrosis factor-alpha
-
COI: 1:CAS:528:DC%2BD3cXnslKhtbo%3D, PID: 11089525
-
Gilbert L, He X, Farmer P et al (2000) Inhibition of osteoblast differentiation by tumor necrosis factor-alpha. Endocrinology 141:3956–3964
-
(2000)
Endocrinology
, vol.141
, pp. 3956-3964
-
-
Gilbert, L.1
He, X.2
Farmer, P.3
-
118
-
-
0037169482
-
Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2alpha A) is inhibited by tumor necrosis factor-alpha
-
COI: 1:CAS:528:DC%2BD38XhtVSgsbw%3D, PID: 11723115
-
Gilbert L, He X, Farmer P et al (2002) Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2alpha A) is inhibited by tumor necrosis factor-alpha. J Biol Chem 277:2695–2701
-
(2002)
J Biol Chem
, vol.277
, pp. 2695-2701
-
-
Gilbert, L.1
He, X.2
Farmer, P.3
-
119
-
-
33645226966
-
Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts
-
COI: 1:CAS:528:DC%2BD28XhtlKkurY%3D, PID: 16373342
-
Kaneki H, Guo R, Chen D et al (2006) Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts. J Biol Chem 281:4326–4333
-
(2006)
J Biol Chem
, vol.281
, pp. 4326-4333
-
-
Kaneki, H.1
Guo, R.2
Chen, D.3
-
120
-
-
0031976864
-
Osteoblast programmed cell death (apoptosis): modulation by growth factors and cytokines
-
COI: 1:CAS:528:DyaK1cXjsVaqurs%3D, PID: 9610743
-
Jilka RL, Weinstein RS, Bellido T, Parfitt AM, Manolagas SC (1998) Osteoblast programmed cell death (apoptosis): modulation by growth factors and cytokines. J Bone Miner Res 13:793–802
-
(1998)
J Bone Miner Res
, vol.13
, pp. 793-802
-
-
Jilka, R.L.1
Weinstein, R.S.2
Bellido, T.3
Parfitt, A.M.4
Manolagas, S.C.5
-
121
-
-
0023465885
-
Interleukin-1 beta is a potent inhibitor of bone formation in vitro
-
COI: 1:CAS:528:DyaL1cXntlGhsA%3D%3D, PID: 3502684
-
Stashenko P, Dewhirst FE, Rooney ML, Desjardins LA, Heeley JD (1987) Interleukin-1 beta is a potent inhibitor of bone formation in vitro. J Bone Miner Res 2:559–565
-
(1987)
J Bone Miner Res
, vol.2
, pp. 559-565
-
-
Stashenko, P.1
Dewhirst, F.E.2
Rooney, M.L.3
Desjardins, L.A.4
Heeley, J.D.5
-
122
-
-
84877092346
-
IL-1beta inhibits human osteoblast migration
-
COI: 1:CAS:528:DC%2BC3sXotVKhu7s%3D, PID: 23508571
-
Hengartner NE, Fiedler J, Ignatius A, Brenner RE (2013) IL-1beta inhibits human osteoblast migration. Mol Med 19:36–42
-
(2013)
Mol Med
, vol.19
, pp. 36-42
-
-
Hengartner, N.E.1
Fiedler, J.2
Ignatius, A.3
Brenner, R.E.4
-
123
-
-
15444362701
-
Cross-talk between the interleukin-6 and prostaglandin E(2) signaling systems results in enhancement of osteoclastogenesis through effects on the osteoprotegerin/receptor activator of nuclear factor-{kappa}B (RANK) ligand/RANK system
-
COI: 1:CAS:528:DC%2BD2MXis1yqurY%3D, PID: 15618359
-
Liu XH, Kirschenbaum A, Yao S, Levine AC (2005) Cross-talk between the interleukin-6 and prostaglandin E(2) signaling systems results in enhancement of osteoclastogenesis through effects on the osteoprotegerin/receptor activator of nuclear factor-{kappa}B (RANK) ligand/RANK system. Endocrinology 146:1991–1998
-
(2005)
Endocrinology
, vol.146
, pp. 1991-1998
-
-
Liu, X.H.1
Kirschenbaum, A.2
Yao, S.3
Levine, A.C.4
-
124
-
-
72749102524
-
Osteoblast function is compromised at sites of focal bone erosion in inflammatory arthritis
-
COI: 1:CAS:528:DC%2BD1MXht1Wju7%2FK, PID: 19338457
-
Walsh NC, Reinwald S, Manning CA et al (2009) Osteoblast function is compromised at sites of focal bone erosion in inflammatory arthritis. J Bone Miner Res 24:1572–1585
-
(2009)
J Bone Miner Res
, vol.24
, pp. 1572-1585
-
-
Walsh, N.C.1
Reinwald, S.2
Manning, C.A.3
-
125
-
-
84875920469
-
Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis
-
PID: 23041840
-
de Rooy DP, Yeremenko NG, Wilson AG et al (2013) Genetic studies on components of the Wnt signalling pathway and the severity of joint destruction in rheumatoid arthritis. Ann Rheum Dis 72:769–775
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 769-775
-
-
de Rooy, D.P.1
Yeremenko, N.G.2
Wilson, A.G.3
-
126
-
-
84908313333
-
Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-kappaB
-
COI: 1:CAS:528:DC%2BC2cXhtlahurnN, PID: 25108526
-
Yu B, Chang J, Liu Y et al (2014) Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-kappaB. Nat Med 20:1009–1017
-
(2014)
Nat Med
, vol.20
, pp. 1009-1017
-
-
Yu, B.1
Chang, J.2
Liu, Y.3
-
127
-
-
20444478272
-
Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis
-
COI: 1:CAS:528:DC%2BD2MXkvF2mu7c%3D, PID: 15902307
-
Lories RJ, Derese I, Luyten FP (2005) Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis. J Clin Invest 115:1571–1579
-
(2005)
J Clin Invest
, vol.115
, pp. 1571-1579
-
-
Lories, R.J.1
Derese, I.2
Luyten, F.P.3
-
128
-
-
84867836732
-
Pathophysiology of new bone formation and ankylosis in spondyloarthritis
-
PID: 23083755
-
Lories RJ, Schett G (2012) Pathophysiology of new bone formation and ankylosis in spondyloarthritis. Rheum Dis Clin North Am 38:555–567
-
(2012)
Rheum Dis Clin North Am
, vol.38
, pp. 555-567
-
-
Lories, R.J.1
Schett, G.2
-
129
-
-
84906319227
-
Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation
-
COI: 1:CAS:528:DC%2BC2cXht1GqtLnM, PID: 25092332
-
Yang L, Tsang KY, Tang HC, Chan D, Cheah KS (2014) Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation. Proc Natl Acad Sci U S A 111:12097–12102
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 12097-12102
-
-
Yang, L.1
Tsang, K.Y.2
Tang, H.C.3
Chan, D.4
Cheah, K.S.5
-
130
-
-
0034069191
-
Quantitative analyses of sacroiliac biopsies in spondyloarthropathies: T cells and macrophages predominate in early and active sacroiliitis- cellularity correlates with the degree of enhancement detected by magnetic resonance imaging
-
COI: 1:STN:280:DC%2BD3c7ivFCgsQ%3D%3D, PID: 10666170
-
Bollow M, Fischer T, Reisshauer H et al (2000) Quantitative analyses of sacroiliac biopsies in spondyloarthropathies: T cells and macrophages predominate in early and active sacroiliitis- cellularity correlates with the degree of enhancement detected by magnetic resonance imaging. Ann Rheum Dis 59:135–140
-
(2000)
Ann Rheum Dis
, vol.59
, pp. 135-140
-
-
Bollow, M.1
Fischer, T.2
Reisshauer, H.3
-
131
-
-
70350558488
-
Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis
-
PID: 19877044
-
Appel H, Ruiz-Heiland G, Listing J et al (2009) Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis. Arthritis Rheum 60:3257–3262
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3257-3262
-
-
Appel, H.1
Ruiz-Heiland, G.2
Listing, J.3
-
132
-
-
84906991087
-
Serum levels of novel noggin and sclerostin-immune complexes are elevated in ankylosing spondylitis
-
Tsui F. W., Tsui H. W., Las Heras F., Pritzker K. P., Inman R. D. (2013) Serum levels of novel noggin and sclerostin-immune complexes are elevated in ankylosing spondylitis. Ann Rheum Dis 73:1873–1879
-
(2013)
Ann Rheum Dis
, vol.73
, pp. 1873-1879
-
-
Tsui, F.W.1
Tsui, H.W.2
Las Heras, F.3
Pritzker, K.P.4
Inman, R.D.5
-
133
-
-
84883818516
-
Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis
-
COI: 1:CAS:528:DC%2BC3sXhs1eis7bO, PID: 23666928
-
Chen XX, Baum W, Dwyer D et al (2013) Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis. Ann Rheum Dis 72:1732–1736
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 1732-1736
-
-
Chen, X.X.1
Baum, W.2
Dwyer, D.3
-
134
-
-
77949473288
-
Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints
-
COI: 1:STN:280:DC%2BC3c7nsFChsA%3D%3D, PID: 19304568
-
Uderhardt S, Diarra D, Katzenbeisser J et al (2010) Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints. Ann Rheum Dis 69:592–597
-
(2010)
Ann Rheum Dis
, vol.69
, pp. 592-597
-
-
Uderhardt, S.1
Diarra, D.2
Katzenbeisser, J.3
-
135
-
-
84869869829
-
Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors
-
PID: 23171658
-
Haynes KR, Pettit AR, Duan R et al (2012) Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors. Arthritis Res Ther 14:R253
-
(2012)
Arthritis Res Ther
, vol.14
, pp. R253
-
-
Haynes, K.R.1
Pettit, A.R.2
Duan, R.3
-
136
-
-
84857910076
-
High level of functional dickkopf-1 predicts protection from syndesmophyte formation in patients with ankylosing spondylitis
-
COI: 1:CAS:528:DC%2BC38XnsFGjs78%3D, PID: 22186710
-
Heiland GR, Appel H, Poddubnyy D et al (2012) High level of functional dickkopf-1 predicts protection from syndesmophyte formation in patients with ankylosing spondylitis. Ann Rheum Dis 71:572–574
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 572-574
-
-
Heiland, G.R.1
Appel, H.2
Poddubnyy, D.3
-
137
-
-
84903700269
-
Biomarkers of bone metabolism in ankylosing spondylitis in relation to osteoproliferation and osteoporosis
-
PID: 24931960
-
Klingberg E, Nurkkala M, Carlsten H, Forsblad-d'Elia H (2014) Biomarkers of bone metabolism in ankylosing spondylitis in relation to osteoproliferation and osteoporosis. J Rheumatol 41:1349–1356
-
(2014)
J Rheumatol
, vol.41
, pp. 1349-1356
-
-
Klingberg, E.1
Nurkkala, M.2
Carlsten, H.3
Forsblad-d'Elia, H.4
-
138
-
-
77957885722
-
Association of bone morphogenetic proteins with spinal fusion in ankylosing spondylitis
-
COI: 1:CAS:528:DC%2BC3cXhsVGhtbvE, PID: 20682677
-
Chen HA, Chen CH, Lin YJ et al (2010) Association of bone morphogenetic proteins with spinal fusion in ankylosing spondylitis. J Rheumatol 37:2126–2132
-
(2010)
J Rheumatol
, vol.37
, pp. 2126-2132
-
-
Chen, H.A.1
Chen, C.H.2
Lin, Y.J.3
-
139
-
-
45549083413
-
Relationship of bone morphogenetic proteins to disease activity and radiographic damage in patients with ankylosing spondylitis
-
COI: 1:CAS:528:DC%2BD1cXnsVyqsLc%3D, PID: 18465455
-
Park MC, Park YB, Lee SK (2008) Relationship of bone morphogenetic proteins to disease activity and radiographic damage in patients with ankylosing spondylitis. Scand J Rheumatol 37:200–204
-
(2008)
Scand J Rheumatol
, vol.37
, pp. 200-204
-
-
Park, M.C.1
Park, Y.B.2
Lee, S.K.3
-
140
-
-
34248178540
-
Serum IL-17, BMP-7, and bone turnover markers in patients with ankylosing spondylitis
-
COI: 1:CAS:528:DC%2BD2sXnsFSmtbc%3D, PID: 17369068
-
Wendling D, Cedoz JP, Racadot E, Dumoulin G (2007) Serum IL-17, BMP-7, and bone turnover markers in patients with ankylosing spondylitis. Joint Bone Spine 74:304–305
-
(2007)
Joint Bone Spine
, vol.74
, pp. 304-305
-
-
Wendling, D.1
Cedoz, J.P.2
Racadot, E.3
Dumoulin, G.4
-
141
-
-
84884414051
-
HLA-B27 misfolding and ankylosing spondylitis
-
COI: 1:CAS:528:DC%2BC3sXhtlGksrzN, PID: 23993278
-
Colbert RA, Tran TM, Layh-Schmitt G (2014) HLA-B27 misfolding and ankylosing spondylitis. Mol Immunol 57:44–51
-
(2014)
Mol Immunol
, vol.57
, pp. 44-51
-
-
Colbert, R.A.1
Tran, T.M.2
Layh-Schmitt, G.3
-
142
-
-
84863697312
-
IL-23 induces spondyloarthropathy by acting on ROR-gammat + CD3 + CD4-CD8- entheseal resident T cells
-
COI: 1:CAS:528:DC%2BC38XpsVWjtLk%3D, PID: 22772566
-
Sherlock JP, Joyce-Shaikh B, Turner SP et al (2012) IL-23 induces spondyloarthropathy by acting on ROR-gammat + CD3 + CD4-CD8- entheseal resident T cells. Nat Med 18:1069–1076
-
(2012)
Nat Med
, vol.18
, pp. 1069-1076
-
-
Sherlock, J.P.1
Joyce-Shaikh, B.2
Turner, S.P.3
-
143
-
-
0035188095
-
The anatomical basis for disease localisation in seronegative spondyloarthropathy at entheses and related sites
-
COI: 1:STN:280:DC%2BD38%2FjsVKjtg%3D%3D, PID: 11760883
-
Benjamin M, McGonagle D (2001) The anatomical basis for disease localisation in seronegative spondyloarthropathy at entheses and related sites. J Anat 199:503–526
-
(2001)
J Anat
, vol.199
, pp. 503-526
-
-
Benjamin, M.1
McGonagle, D.2
-
144
-
-
84884411123
-
The critical role of interleukin-23 in spondyloarthropathy
-
COI: 1:CAS:528:DC%2BC3sXht1SkurjN, PID: 23910729
-
Sherlock JP, Buckley CD, Cua DJ (2014) The critical role of interleukin-23 in spondyloarthropathy. Mol Immunol 57:38–43
-
(2014)
Mol Immunol
, vol.57
, pp. 38-43
-
-
Sherlock, J.P.1
Buckley, C.D.2
Cua, D.J.3
-
145
-
-
84873725322
-
Microscopic gut inflammation in axial spondyloarthritis: a multiparametric predictive model
-
PID: 23139267
-
Van Praet L, Van den Bosch FE, Jacques P et al (2013) Microscopic gut inflammation in axial spondyloarthritis: a multiparametric predictive model. Ann Rheum Dis 72:414–417
-
(2013)
Ann Rheum Dis
, vol.72
, pp. 414-417
-
-
Van Praet, L.1
Van den Bosch, F.E.2
Jacques, P.3
-
146
-
-
84903907928
-
Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation
-
COI: 1:CAS:528:DC%2BC2cXhsFKntLjL, PID: 23740229
-
Ciccia F, Accardo-Palumbo A, Rizzo A et al (2014) Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation. Ann Rheum Dis 73:1566–1574
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 1566-1574
-
-
Ciccia, F.1
Accardo-Palumbo, A.2
Rizzo, A.3
-
147
-
-
84896285523
-
Review: The interleukin-23/interleukin-17 axis in spondyloarthritis pathogenesis: Th17 and beyond
-
COI: 1:CAS:528:DC%2BC2cXhtl2gt7rP, PID: 24504793
-
Smith JA, Colbert RA (2014) Review: The interleukin-23/interleukin-17 axis in spondyloarthritis pathogenesis: Th17 and beyond. Arthritis Rheumatol 66:231–241
-
(2014)
Arthritis Rheumatol
, vol.66
, pp. 231-241
-
-
Smith, J.A.1
Colbert, R.A.2
-
148
-
-
84857624302
-
Associations between interleukin-23R polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis
-
COI: 1:CAS:528:DC%2BC38XhtlWitr0%3D, PID: 22089529
-
Lee YH, Choi SJ, Ji JD, Song GG (2012) Associations between interleukin-23R polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis. Inflamm Res 61:143–149
-
(2012)
Inflamm Res
, vol.61
, pp. 143-149
-
-
Lee, Y.H.1
Choi, S.J.2
Ji, J.D.3
Song, G.G.4
-
149
-
-
84902975020
-
IL-23 promotes osteoclastogenesis in osteoblast-osteoclast co-culture system
-
COI: 1:CAS:528:DC%2BC2cXhslaitrzL, PID: 25036517
-
Kang YK, Zhang MC (2014) IL-23 promotes osteoclastogenesis in osteoblast-osteoclast co-culture system. Genet Mol Res 13:4673–4679
-
(2014)
Genet Mol Res
, vol.13
, pp. 4673-4679
-
-
Kang, Y.K.1
Zhang, M.C.2
-
150
-
-
58149242827
-
IL-23 promotes osteoclast formation by up-regulation of receptor activator of NF-kappaB (RANK) expression in myeloid precursor cells
-
COI: 1:CAS:528:DC%2BD1cXhtlOjsL7K, PID: 18958885
-
Chen L, Wei XQ, Evans B, Jiang W, Aeschlimann D (2008) IL-23 promotes osteoclast formation by up-regulation of receptor activator of NF-kappaB (RANK) expression in myeloid precursor cells. Eur J Immunol 38:2845–2854
-
(2008)
Eur J Immunol
, vol.38
, pp. 2845-2854
-
-
Chen, L.1
Wei, X.Q.2
Evans, B.3
Jiang, W.4
Aeschlimann, D.5
-
151
-
-
36448931232
-
IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats
-
PID: 17888176
-
Yago T, Nanke Y, Kawamoto M et al (2007) IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats. Arthritis Res Ther 9:R96
-
(2007)
Arthritis Res Ther
, vol.9
, pp. R96
-
-
Yago, T.1
Nanke, Y.2
Kawamoto, M.3
-
152
-
-
0034795511
-
An enthesitis based model for the pathogenesis of spondyloarthropathy. additive effects of microbial adjuvant and biomechanical factors at disease sites
-
COI: 1:STN:280:DC%2BD3MrmsFyluw%3D%3D, PID: 11669149
-
McGonagle D, Stockwin L, Isaacs J, Emery P (2001) An enthesitis based model for the pathogenesis of spondyloarthropathy. additive effects of microbial adjuvant and biomechanical factors at disease sites. J Rheumatol 28:2155–2159
-
(2001)
J Rheumatol
, vol.28
, pp. 2155-2159
-
-
McGonagle, D.1
Stockwin, L.2
Isaacs, J.3
Emery, P.4
-
153
-
-
84891747499
-
Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells
-
PID: 23921997
-
Jacques P, Lambrecht S, Verheugen E et al (2014) Proof of concept: enthesitis and new bone formation in spondyloarthritis are driven by mechanical strain and stromal cells. Ann Rheum Dis 73:437–445
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 437-445
-
-
Jacques, P.1
Lambrecht, S.2
Verheugen, E.3
-
154
-
-
43949140512
-
Radiographic progression of ankylosing spondylitis after up to two years of treatment with etanercept
-
PID: 18438853
-
van der Heijde D, Landewe R, Einstein S et al (2008) Radiographic progression of ankylosing spondylitis after up to two years of treatment with etanercept. Arthritis Rheum 58:1324–1331
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1324-1331
-
-
van der Heijde, D.1
Landewe, R.2
Einstein, S.3
-
155
-
-
54949113223
-
Radiographic findings following two years of infliximab therapy in patients with ankylosing spondylitis
-
PID: 18821688
-
van der Heijde D, Landewe R, Baraliakos X et al (2008) Radiographic findings following two years of infliximab therapy in patients with ankylosing spondylitis. Arthritis Rheum 58:3063–3070
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3063-3070
-
-
van der Heijde, D.1
Landewe, R.2
Baraliakos, X.3
-
156
-
-
73349110978
-
Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years
-
PID: 19703304
-
van der Heijde D, Salonen D, Weissman BN et al (2009) Assessment of radiographic progression in the spines of patients with ankylosing spondylitis treated with adalimumab for up to 2 years. Arthritis Res Ther 11:R127
-
(2009)
Arthritis Res Ther
, vol.11
, pp. R127
-
-
van der Heijde, D.1
Salonen, D.2
Weissman, B.N.3
-
157
-
-
84885126123
-
The impact of tumor necrosis factor alpha inhibitors on radiographic progression in ankylosing spondylitis
-
COI: 1:CAS:528:DC%2BC3sXhsF2htL3L, PID: 23818109
-
Haroon N, Inman RD, Learch TJ et al (2013) The impact of tumor necrosis factor alpha inhibitors on radiographic progression in ankylosing spondylitis. Arthritis Rheum 65:2645–2654
-
(2013)
Arthritis Rheum
, vol.65
, pp. 2645-2654
-
-
Haroon, N.1
Inman, R.D.2
Learch, T.J.3
-
158
-
-
84895490291
-
Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis
-
COI: 1:CAS:528:DC%2BC2cXosVehs70%3D, PID: 23505240
-
Baraliakos X, Haibel H, Listing J, Sieper J, Braun J (2014) Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis. Ann Rheum Dis 73:710–715
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 710-715
-
-
Baraliakos, X.1
Haibel, H.2
Listing, J.3
Sieper, J.4
Braun, J.5
|