Overexpression of secreted frizzled-related protein 1 inhibits bone formation and attenuates parathyroid hormone bone anabolic effects

Journal of Bone and Mineral Research

Volumn 25, Issue 2, 2010, Pages 190-199

  Yao, Wei ^a   Cheng, Zhiqiang ^a   Shahnazari, Mohammad ^a   Dai, Wewei ^a   Johnson, Mark L ^b   Lane, Nancy E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF DENTISTRY   (United States)

Author keywords

Bone mass; PTH; Sex difference; sFRP1; Transgenic

Indexed keywords

BIOCHEMICAL MARKER; PARATHYROID HORMONE[1-34]; SECRETED FRIZZLED RELATED PROTEIN 1; MEMBRANE PROTEIN; PARATHYROID HORMONE; SFRP1 PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE; BONE DEVELOPMENT; BONE MARROW CELL; BONE MASS; BONE TURNOVER; CELL CULTURE; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; FEMALE; FEMUR; GENE CONTROL; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HORMONE RECEPTOR INTERACTION; LUMBAR SPINE; MALE; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; SEX DIFFERENCE; TRABECULAR BONE; TREATMENT DURATION; WILD TYPE; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; BONE RESORPTION; CELL DIFFERENTIATION; CELLS, CULTURED; FEMALE; GENE EXPRESSION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; OSTEOBLASTS; OSTEOCLASTS; OSTEOGENESIS; PARATHYROID HORMONE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 77951998251     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.090719     Document Type: Article

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