Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia

Bone

Volumn 39, Issue 4, 2006, Pages 754-766

  Li, Ji ^a   Sarosi, Ildiko ^a   Cattley, Russell C ^a   Pretorius, James ^a   Asuncion, Frank ^a   Grisanti, Mario ^a   Morony, Sean ^a   Adamu, Stephen ^a   Geng, Zhaopo ^a   Qiu, Wanrong ^a   Kostenuik, Paul ^a   Lacey, David L ^a   Simonet, W Scott ^a   Bolon, Brad ^b   Qian, Xueming ^a   Shalhoub, Victoria ^a   Ominsky, Michael S ^a   Zhu Ke, Hua ^a   Li, Xiaodong ^a   Richards, William G ^a  

^a AMGEN INC   (United States)

^b GEMpath Inc   (United States)

Author keywords

Bone mass; Dickkopf 1; Expression; Osteoporosis; Transgenic

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 1 A 1; DICKKOPF 1 PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; OSTEOCALCIN; PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ALOPECIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MASS; BONE MINERAL; BONE MINERALIZATION; CELL COUNT; CONTROLLED STUDY; DISEASE SEVERITY; EMBRYO; FEMALE; FORELIMB; GENE OVEREXPRESSION; LIMB DEFECT; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; NUDE MOUSE; OSSIFICATION; OSTEOBLAST; OSTEOCYTE; OSTEOPENIA; PHENOTYPE; PROMOTER REGION; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; TRANSGENIC MOUSE;

3T3 CELLS; ANIMALS; BONE AND BONES; BONE DENSITY; BONE DISEASES, METABOLIC; CELLS, CULTURED; EMBRYO; EMBRYO, MAMMALIAN; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IN SITU HYBRIDIZATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LDL-RECEPTOR RELATED PROTEINS; MALE; MICE; MICE, TRANSGENIC; OSTEOBLASTS; OSTEOCALCIN; OSTEOGENESIS; PREGNANCY; RATS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 33748156090     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2006.03.017     Document Type: Article

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