Osteoblast programmed cell death (apoptosis): Modulation by growth factors and cytokines

Journal of Bone and Mineral Research

Volumn 13, Issue 5, 1998, Pages 793-802

  Jilka, Robert L ^a   Weinstein, Robert S ^a   Bellido, Teresita ^a   Parfitt, A Michael ^a   Manolagas, Stavros C ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DNA FRAGMENT; FAS ANTIGEN; GROWTH FACTOR; INTERLEUKIN 6; ONCOSTATIN M; PROTEIN BAX; PROTEIN BCL 2; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MATRIX; BONE REMODELING; CELL DEATH; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOID;

ANIMALS; APOPTOSIS; BONE AND BONES; BONE REMODELING; CELL LINE; CYTOKINES; GROWTH SUBSTANCES; HUMANS; INTERLEUKIN-6; MICE; OSTEOBLASTS; RECEPTORS, INTERLEUKIN-6; RECOMBINANT PROTEINS; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031976864     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1998.13.5.793     Document Type: Article

References (40)

1. Parfitt AM 1994 Osteonal and hemi-osteonal remodeling: The spatial and temporal framework for signal traffic in adult human bone. J Cell Biochem 55:273-286.
2. Manolagas SC, Jilka RL 1995 Mechanisms of disease: Bone marrow, cytokines, and bone remodeling - Emerging insights into the pathophysiology of osteoporosis. N Engl J Med 332: 305-311.
3. Jilka RL, Weinstein RS, Takahashi K, Parfitt AM, Manolagas SC 1996 Linkage of decreased bone mass with impaired osteoblastogenesis in a murine model of accelerated senescence. J Clin Invest 97:1732-1740.
4. Steller H 1995 Mechanisms and genes of cellular suicide. Science 267:1445-1449.
5. Polunovsky VA, Chen B, Henke C, Snover D, Wendt C, Ingbar DH, Bitterman PB 1993 Role of mesenchymal cell death in lung remodeling after injury. J Clin Invest 92:388-397.
6. Hughes DE, Wright KR, Uy HL, Sasaki A, Yoneda T, Roodman GD, Mundy GR, Boyce BF 1995 Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo. J Bone Miner Res 10:1478-1487.
7. Lutton JD, Moonga BS, Dempster DW 1996 Osteoclast demise in the rat: Physiological versus degenerative cell death. Exp Physiol 81:251-260.
8. Hughes DE, Dai A, Tiffee JC, Li HH, Mundy GR, Boyce BF 1996 Estrogen promotes apoptosis of murine osteoclasts mediated by TGF-β. Nature Med 2:1132-1136.
9. Hill PA, Tumber A, Meikle MC 1997 Multiple extracellular signals promote osteoblast survival and apoptosis. Endocrinology 138:3849-3858.
10. Kitajima I, Soejima Y, Takasaki I, Beppu H, Tokioka T, Maruyama I 1996 Ceramide-induced nuclear translocation of NF-kappaB is a potential mediator of the apoptotic response to TNF-α in murine clonal osteoblasts. Bone 19:263-270.
11. Bronkers ALJJ, Goei W, Luo G, Karsenty G, D'Souza RN, Lyaruu DM, Burger EH 1996 DNA fragmentation during bone formation in neonatal rodents assessed by transferase-mediated end labeling. J Bone Miner Res 11:1281-1291.
12. Arnott N, Skerry TM, Beresford JN 1995 Evidence for a role of programmed cell death in the regulation of bone formation in adult human bone. J Bone Miner Res 10:S216 (abstract).
13. Parfitt AM 1990 Bone-forming cells in clinical conditions. In: Hall BK (ed.) Bone, Vol 1: The Osteoblast and Osteocyte. Telford Press and CRC Press, Boca Raton, FL, U.S.A., pp. 351-429.
14. Collins MK, Perkins GR, Rodriguez-Tarduchy G, Nieto MA, Lopez-Rivas A 1994 Growth factors as survival factors: Regulation of apoptosis. BioEssays 16:133-138.
15. Beck TW, Magnuson NS, Rapp UR 1995 Growth factor regulation of cell cycle progression and cell fate determination. Curr Top Microbiol Immunol 194:291-303.
16. Ben-Sasson SA, Sherman Y, Gavrieli Y 1995 Methods in Cell Biology: Identification of Dying Cells - In Situ Staining. Academic Press, Inc., New York, NY, U.S.A., pp. 29-39.
17. Wang E 1995 Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved. Cancer Res 55:2284-2292.
18. Earnshaw WC 1995 Nuclear changes in apoptosis. Curr Opin Cell Biol 7:337-343.
19. Kawano MM, Mihara K, Huang N, Tsujimoto T, Kuramoto A 1995 Differentiation of early plasma cells on bone marrow stromal cells requires interleukin-6 for escaping from apoptosis. Blood 85:487-494.
20. Pesce M, Farrace MG, Piacentini M, Dolci S, De Felici M 1993 Stem cell factor and leukemia inhibitory factor promote primordial germ cell survival by suppressing programmed cell death (apoptosis). Development 118:1089-1094.
21. Manolagas SC, Jilka RL, Bellido T, O'Brien CA, Parfitt AM 1996 Interleukin-6-type cytokines and their receptors. In: Bilezikian JP, Raisz LG, Rodan GA (eds.) Principles of Bone Biology. Academic Press, San Diego, CA, U.S.A., pp. 701-713.
22. Bellido T, Stahl N, Farruggella TJ, Borba V, Yancopoulos GD, Manolagas SC 1996 Detection of receptors for interleukin-6, interleukin-11, leukemia inhibitory factor, oncostatin M, and ciliary neurotrophic factor in bone marrow stromal/osteoblastic cells. J Clin Invest 97:431-437.
23. + human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro. Blood 85:3183-3190.
24. Gajewski TF, Thompson CB 1996 Apoptosis meets signal transduction: Elimination of a BAD influence. Cell 87:589-592.
25. Taichman RS, Hauschka PV 1992 Effects of interleukin-1β and tumor necrosis factor-α on osteoblastic expression of osteocalcin and mineralized extracellular matrix in vitro. Inflammation 16:587-601.
26. Ware CF, VanArsdale S, VanArsdale TL 1996 Apoptosis mediated by the TNF-related cytokine and receptor families. J Cell Biochem 60:47-55.
27. Van Antwerp DJ, Martin SJ, Kafri T, Green DR, Verma IM 1996 Suppression of TNF-α-induced apoptosis by NF-kappaB. Science 274:787-789.
28. Chauhan D, Kharbanda S, Ogata A, Urashima M, Teoh G, Robertson M, Kufe DW, Anderson KC 1997 Interleukin-6 inhibits Fas-induced apoptosis and stress-activated protein kinase activation in multiple myeloma cells. Blood 89:227-234.
29. Kawakami A, Eguchi K, Matsuoka N, Tsuboi M, Kawabe Y, Aoyagi T, Nagataki S 1996 Inhibition of Fas antigen-mediated apoptosis of rheumatoid synovial cells in vitro by transforming growth factor β1. Arthritis Rheum 39:1267-1276.
30. WAF1,CIP1 gene in osteoblasts: A prerequisite for the biologic effects of IL-6 type cytokines. J Bone Miner Res 12:S159 (abstract).
31. Moulton BC 1994 Transforming growth factor-β stimulates endometrial stromal apoptosis in vitro. Endocrinology 134: 1055-1060.
32. Bursch W, Paffe S, Putz B, Barthel G, Schulte-Hermann R 1990 Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats. Carcinogenesis 11:847-853.
33. Gavrieli Y, Sherman Y, Ben-Sasson SA 1992 Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501.
34. Tanaka S, Amling M, Neff L, Peyman A, Uhlmannn E, Levy JB, Baron R 1996 c-Cb1 is downstream of c-Src in a signaling pathway necessary for bone resorption. Nature 383:528-531.
35. Weinstein RS, Jilka RL, Parfitt AM, Manolagas SC 1997 The effects of androgen deficiency on murine bone remodeling and bone mineral density are mediated via cells of the osteoblastic lineage. Endocrinology 138:4013-4021.
36. Parfitt AM, Drezner MK, Glorieuxn FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR 1987 Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2:595-610.
37. Jilka RL, Takahashi K, Munshi M, Williams DC, Roberson PK, Manolagas SC 1998 Loss of estrogen upregulates osteoblastogenesis in the murine bone marrow: Evidence for autonomy from factors released during bone resorption. J Clin Invest (in press).
38. Yang NN, Bryant HU, Hardikar S, Sato M, Galvin RJS, Glasebrook AL, Termine JD 1996 Estrogen and raloxifene stimulate transforming growth factor-β3 gene expression in rat bone: A potential mechanism for estrogen-or raloxifene-mediated bone maintenance. Endocrinology 137:2075-2084.
39. Lin S-C, Yamate T, Yaguchi Y, Borba VCZ, Girasole G, O'Brien CA, Bellido T, Abe E, Manolagas SC 1997 Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow. J Clin Invest 100:1980-1990.
40. Stashenko P, Obernesser MS, Dewhirst FE 1989 Effect of immune cytokines on bone. Immunol Invest 18:239-249.