Interleukin-6 directly inhibits osteoclast differentiation by suppressing receptor activator of NF-κB signaling pathways

Journal of Biological Chemistry

Volumn 283, Issue 17, 2008, Pages 11535-11540

  Yoshitake, Fumio ^a   Itoh, Shousaku ^a   Narita, Hiroko ^a   Ishihara, Katsuhiko ^b   Ebisu, Shigeyuki ^a  

^a OSAKA UNIVERSITY   (Japan)

^b KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; DIFFERENTIATION (CALCULUS); PIGMENTS; PROTEINS; SIGNALING; TRANSCRIPTION;

BONE HOMEOSTASISES; COSTIMULATION; CYTOKINE; IMMUNE RESPONSES; JNK ACTIVATIONS; MICROARRAY ANALYSIS; MULTI-FUNCTIONAL; OSTEOCLAST DIFFERENTIATIONS; RANK SIGNALING; RECEPTOR ACTIVATORS; SIGNALING PATHWAYS; UBIQUITIN PATHWAYS;

ELECTRIC LOAD MANAGEMENT;

CULLIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 7; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN CUL4A; PROTEIN SENP2; PROTEINASE; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; DUAL SPECIFICITY PHOSPHATASE; DUSP1 PROTEIN, MOUSE; DUSP16 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UBIQUITINATION; ANIMAL; BIOLOGICAL MODEL; BONE MARROW CELL; CYTOLOGY; GENE EXPRESSION REGULATION; METABOLISM; PHOSPHORYLATION;

ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; DUAL SPECIFICITY PHOSPHATASE 1; DUAL-SPECIFICITY PHOSPHATASES; GENE EXPRESSION REGULATION; INTERLEUKIN-6; MAP KINASE KINASE 4; MICE; MITOGEN-ACTIVATED PROTEIN KINASE PHOSPHATASES; MODELS, BIOLOGICAL; NF-KAPPA B; OSTEOCLASTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 45549097409     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M607999200     Document Type: Article

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